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Recombinant Human Insulin

Detailed information about Recombinant Human Insulin

Official label facts Owner quick guide first Marketing clearly labeled

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Reviewed / Updated / Sources

Reviewed: Not available

Updated: February 12, 2026, 10:44 PM UTC

Sources:

Pet Owner Quick Guide

Start here first for the simple next-step summary.

Used for:

Your vet decides this. Here's what owners typically ask/watch for.

What to watch for:

  • Weight loss (1 reports)
  • Weakness (1 reports)
  • Vomiting (1 reports)

When to call the vet:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
  • Facial swelling or hives.
  • Blood in vomit or stool.

What to ask your vet today:

  • Is this medicine the right fit for my pet’s current symptoms?
  • Which warning signs mean I should call back right away?
  • How should I handle missed doses or refusal to take the medicine?
Safety & side effects

What to watch:

  • Weight loss
  • Weakness
  • Vomiting

Most reported reactions:

  • Weight loss (1 reports)
  • Weakness (1 reports)
  • Vomiting (1 reports)

When to call your vet:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.

Data freshness: source data appears current.

Latest refresh: Mar 21, 2026, 10:01 a.m.

Data freshness
  • Medication catalog: Source Roxee | Refreshed Feb 12, 2026, 10:44 PM UTC
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed Mar 21, 2026, 10:01 AM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
  • openFDA reaction terms: Source FDA openFDA | Refreshed Feb 9, 2026, 3:14 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Feb 9, 2026, 3:21 AM UTC
Image coming soon
Recombinant Human Insulin

Recombinant Human Insulin

Drug type: Generic ingredient • Generic profile No FDA branded products linked

Species: Both

Manufacturer: Not available (source)

Quick Facts

Official label facts first, then secondary summaries. Marketing content is separated below.

Species: Both
Manufacturer: Not available
Identifiers:
NDC Package: 0010-4499-01 NDC Package: 0010-4499-02 NDC Product: 0010

Adverse Reactions

Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.

Tap or hover a reaction to see what it means in plain language.

Tracked signals
28
Reported cases
19
Serious reports
13
Species represented
2
Grouped by Body System
Digestive (3) · Vomiting, Diarrhea, Decreased appetite Neurologic (3) · Tiredness (lethargy), Seizure NOS, Lethargy (see also Central nervous system depression in 'Neurological') Behavior (1) · Anxiety Effectiveness (2) · Partial lack of efficacy, Lack of efficacy - NOS Other (19) · Weight loss, Weakness, Otitis externa
Most Reported Reactions
Reaction Body system Cases Species Serious cases
Other 1 Cat 1
Other 1 Cat 1
Digestive 1 Cat 1
Neurologic 1 Cat 1
Neurologic 1 Cat 1
Other 1 Cat 1
Other 1 Cat 1
Other 1 Cat 1

Species coverage: Cat (18) Dog (10)

View detailed reaction table
Reaction Body system Species Seriousness Frequency Reports
Other Cat Serious - 1
Other Cat Serious - 1
Digestive Cat Serious - 1
Neurologic Cat Serious - 1
Neurologic Cat Serious - 1
Effectiveness Dog Non-serious - 1
Other Dog Non-serious - 1
Other Dog Non-serious - 1
Other Cat Non-serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Dog Non-serious - 1
Digestive Cat Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Digestive Cat Serious - 1
Other Dog Non-serious - 1
Other Cat Serious - 1
Other Dog Unknown - -
Other Dog Unknown - -
Neurologic Dog Unknown - -
Effectiveness Cat Unknown - -
Other Cat Unknown - -
Other Cat Unknown - -
Other Dog Unknown - -
Behavior Dog Unknown - -
Other Cat Unknown - -
Source metadata:
Veterinary reference (advanced)

Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.

At a Glance

Quick facts and links to official labeling and safety signals.

Data freshness
  • Medication catalog: Source Roxee | Refreshed Feb 12, 2026, 10:44 PM UTC
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed Mar 21, 2026, 10:01 AM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
  • openFDA reaction terms: Source FDA openFDA | Refreshed Feb 9, 2026, 3:14 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Feb 9, 2026, 3:21 AM UTC
Official (FDA)
Identity: Generic ingredient • No FDA branded products linked
No official FDA brand rows linked yet for this ingredient.
Case-reported brands (openFDA): MSK
Catalog species: Both
Safety (openFDA)
Top reactions: Dog 8 Cat 8 View
Case summaries: 10 (showing 8) View
openFDA reports are unverified and do not prove causation.

Diagnosis Codes

Diagnosis-code mappings are not available for this medication yet.

Counseling and Monitoring Highlights

Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.

Top reaction signals
Weight loss (1) Weakness (1) Vomiting (1) Tiredness (lethargy) (1) Seizure NOS (1) Hypothermia (1) Hypoglycaemia (1) Fever (1)

Identifiers & Packages

Normalized identifiers (NDC/NADA/ANADA) and package metadata from regulator listings.

Identifiers
NDC Package: 0010-4499-01 NDC Package: 0010-4499-02 NDC Product: 0010
Package NDC Product NDC Form / Route Status
0010-4499-01 0010 -
0010-4499-02 0010 -

Data Sources & Change Log

Every non-trivial field is expected to include provenance and update timestamps.

Official 1 Clinical 0 Manufacturer 0 Marketing 0
Current Field Facts
  • side_effects: Top reported reactions (openFDA): Vomiting, Lethargy (see also Central nervous system depression in 'Neurological'), Cataract, Decreased appetite, Diarrhoea, P… (Official, 2026-02-12)
Recent Revisions
  • side_effects updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields

Top Reported Reactions (openFDA)

De-duplicated reaction terms grouped by body system from FDA openFDA reports (not verified; does not prove causation).

Digestive
Vomiting (1) • Cat Diarrhea (1) • Cat Decreased appetite (1) • Cat

Showing top 5 for Digestive.

Neurologic
Tiredness (1) • Cat Seizure NOS (1) • Cat Tiredness (lethargy) • Dog

Showing top 5 for Neurologic.

Behavior
Anxiety • Dog

Showing top 5 for Behavior.

Effectiveness
Partial lack of efficacy (1) • Dog Lack of efficacy - NOS • Cat

Showing top 5 for Effectiveness.

Other
Weight loss (1) • Cat Weakness (1) • Cat Otitis externa (1) • Dog Keratoconjunctivitis sicca (1) • Dog INEFFECTIVE, GLYCEMIC CONTROL (1) • Cat
Show more (14)
Hypothermia (1) • Cat Hypoglycaemia (1) • Cat Fever (1) • Cat Enlarged lymph node (1) • Dog Diabetic ketoacidosis (1) • Cat Dehydration (1) • Cat Cough (1) • Dog Blindness (1) • Cat Polyuria • Dog Polydipsia • Dog Death by euthanasia • Cat Death • Cat Cataract • Dog Abnormal test result • Cat

Showing top 5 for Other.

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Adverse Event Case Summaries (openFDA)

These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.

Cat, Domestic Shorthair, Male, 10 year, 6.4 kilogram • Drug: MSK, Suspension, Subcutaneous, Dose: 0.25 [iU] per kilogram, Frequency: 12 per hour • Reactions: Diarrhea, Vomiting, Decreased appetite, Fever, Weakness… • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2017-US-036524
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 10.00 Year
  • Weight: 6.400 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Subcutaneous
  • Form: Suspension
  • Dose: 0.25 [iU] per kilogram
  • Frequency: 12 per hour
Reactions Reported:
Diarrhea Vomiting Decreased appetite Fever Weakness Dehydration Hypothermia Weight loss Diabetic ketoacidosis
Outcomes: Recovered/Normal

Cat, Domestic Shorthair, Male, 13 year, 6.713 kilogram • Drug: MSK, Suspension, Subcutaneous • Reactions: INEFFECTIVE, GLYCEMIC CONTROL • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2017-US-028270
  • Serious AE: No
  • Treated For AE: Yes
  • Sex: Male
  • Age: 13.00 Year
  • Weight: 6.713 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Subcutaneous
  • Form: Suspension
Reactions Reported:
INEFFECTIVE, GLYCEMIC CONTROL
Outcomes: Recovered/Normal

Cat, Domestic Longhair, Male, 15 year, 5.08 kilogram • Drug: MSK, Suspension, Subcutaneous, Dose: 0.88 [iU] per kilogram, Frequency: 12 per hour • Reactions: Hypoglycaemia, Vomiting • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2017-US-027489
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 15.00 Year
  • Weight: 5.080 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Subcutaneous
  • Form: Suspension
  • Dose: 0.88 [iU] per kilogram
  • Frequency: 12 per hour
Reactions Reported:
Hypoglycaemia Vomiting
Outcomes: Recovered/Normal

Cat, Domestic Shorthair, Unknown, 6.804 kilogram • Drug: MSK, Suspension, Subcutaneous, Dose: 0.59 [iU] per kilogram, Frequency: 12 per hour • Reactions: Hypoglycaemia, Blindness, Seizure NOS, Tiredness (lethargy) • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2017-US-027773
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Unknown
  • Weight: 6.804 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Subcutaneous
  • Form: Suspension
  • Dose: 0.59 [iU] per kilogram
  • Frequency: 12 per hour
Reactions Reported:
Hypoglycaemia Blindness Seizure NOS Tiredness (lethargy)
Outcomes: Ongoing

Cat, Domestic Mediumhair, Female, 12 year, 6.577 kilogram • Drug: MSK, Suspension, Subcutaneous, Dose: 0.30 [iU] per kilogram, Frequency: 12 per hour • Reactions: INEFFECTIVE, GLYCEMIC CONTROL • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2017-US-026168
  • Serious AE: No
  • Treated For AE: Yes
  • Sex: Female
  • Age: 12.00 Year
  • Weight: 6.577 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Subcutaneous
  • Form: Suspension
  • Dose: 0.30 [iU] per kilogram
  • Frequency: 12 per hour
Reactions Reported:
INEFFECTIVE, GLYCEMIC CONTROL
Outcomes: Outcome Unknown

Dog, Pug, Female, 7 year, 15.876 kilogram • Drug: MSK, Suspension, Subcutaneous, Dose: 0.69 [iU] per kilogram, Frequency: 12 per hour • Reactions: Partial lack of efficacy • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2016-US-055394
  • Serious AE: No
  • Treated For AE: No
  • Sex: Female
  • Age: 7.00 Year
  • Weight: 15.876 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Subcutaneous
  • Form: Suspension
  • Dose: 0.69 [iU] per kilogram
  • Frequency: 12 per hour
Reactions Reported:
Partial lack of efficacy
Outcomes: Outcome Unknown

Dog, Bichon Frise, Male, 11 year, 11.3 kilogram • Drug: MSK, Suspension, Subcutaneous, Dose: 0.75 [iU] per kilogram, Frequency: 1 per day • Reactions: Diarrhea • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2016-US-051783
  • Serious AE: No
  • Treated For AE: No
  • Sex: Male
  • Age: 11.00 Year
  • Weight: 11.300 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Subcutaneous
  • Form: Suspension
  • Dose: 0.75 [iU] per kilogram
  • Frequency: 1 per day
Reactions Reported:
Diarrhea
Outcomes: Recovered/Normal

Dog, Crossbred Canine/dog, Male, 12 year, 7.9 kilogram • Drug: MSK, Suspension, Subcutaneous, Dose: 1.65 [iU] per kilogram, Frequency: 1 per day • Reactions: Cough, Enlarged lymph node • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2016-US-051784
  • Serious AE: No
  • Treated For AE: Yes
  • Sex: Male
  • Age: 12.00 Year
  • Weight: 7.900 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Subcutaneous
  • Form: Suspension
  • Dose: 1.65 [iU] per kilogram
  • Frequency: 1 per day
Reactions Reported:
Cough Enlarged lymph node
Outcomes: Recovered/Normal

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Overdose Information

No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.

Storage & Handling

No approved storage guidance is linked yet for this ingredient. Use manufacturer packaging and veterinary guidance for handling/storage.

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This medication has not been reviewed by a veterinarian yet.