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Phenylpropanolamine Hcl

Detailed information about Phenylpropanolamine Hcl

Official label facts Owner quick guide first Marketing clearly labeled
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Reviewed / Updated / Sources

Reviewed: Not available

Updated: February 12, 2026, 10:44 PM UTC

Sources:

Pet Owner Quick Guide

Start here first for the simple next-step summary.

Used for:

Your vet decides this. Here's what owners typically ask/watch for.

What to watch for:

  • Regurgitation (1 reports)
  • Peritonitis (1 reports)
  • Gastric ulcer (1 reports)

When to call the vet:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
  • Facial swelling or hives.
  • Blood in vomit or stool.

What to ask your vet today:

  • Is this medicine the right fit for my pet’s current symptoms?
  • Which warning signs mean I should call back right away?
  • How should I handle missed doses or refusal to take the medicine?
Safety & side effects

What to watch:

  • Regurgitation
  • Peritonitis
  • Gastric ulcer

Most reported reactions:

  • Regurgitation (1 reports)
  • Peritonitis (1 reports)
  • Gastric ulcer (1 reports)

When to call your vet:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
Talk to a Vet / Find a Vet Near You Start Symptom Intake

Data freshness: source data appears current.

Latest refresh: Mar 21, 2026, 10:01 a.m.

Data freshness
  • Medication catalog: Source Roxee | Refreshed Feb 12, 2026, 10:44 PM UTC
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed Mar 21, 2026, 10:01 AM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
  • openFDA reaction terms: Source FDA openFDA | Refreshed Feb 9, 2026, 3:14 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Feb 9, 2026, 3:21 AM UTC
Image coming soon
Phenylpropanolamine Hcl

Phenylpropanolamine Hcl

Drug type: Generic ingredient • Generic profile • No FDA branded products linked

Species: Both

Manufacturer: Not available (source)

Quick Facts

Official label facts first, then secondary summaries. Marketing content is separated below.

Species: Both
Manufacturer: Not available

Adverse Reactions

Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.

Tap or hover a reaction to see what it means in plain language.

Tracked signals
21
Reported cases
16
Serious reports
3
Species represented
2
Grouped by Body System
Digestive (1) · Vomiting Skin & allergy (1) · Erythema (for urticaria see Immune SOC) Neurologic (1) · Lethargy (see also Central nervous system depression in 'Neurological') Effectiveness (4) · Lack of efficacy - NOS, Lack of efficacy (endoparasite) - hookworm, Lack of efficacy (ectoparasite) - tick NOS Other (14) · Uncomfortable, Strabismus, Shaking
Most Reported Reactions
Reaction Body system Cases Species Serious cases
Other 1 Dog 1
Other 1 Dog 1
Other 1 Dog 1
Digestive 1 Cat 0
Other 1 Dog 0
Other 1 Dog 0
Other 1 Dog 0
Other 1 Dog 0

Species coverage: Dog (18) Cat (3)

View detailed reaction table
Reaction Body system Species Seriousness Frequency Reports
Digestive Cat Non-serious - 1
Other Dog Non-serious - 1
Other Dog Non-serious - 1
Other Dog Non-serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Non-serious - 1
Effectiveness Cat Non-serious - 1
Effectiveness Dog Non-serious - 1
Effectiveness Dog Non-serious - 1
Effectiveness Dog Non-serious - 1
Other Dog Non-serious - 1
Other Dog Non-serious - 1
Other Dog Serious - 1
Other Dog Non-serious - 1
Other Cat Non-serious - 1
Other Dog Unknown - -
Other Dog Unknown - -
Neurologic Dog Unknown - -
Skin & allergy Dog Unknown - -
Other Dog Unknown - -
Source metadata:
Veterinary reference (advanced)

Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.

At a Glance

Quick facts and links to official labeling and safety signals.

Data freshness
  • Medication catalog: Source Roxee | Refreshed Feb 12, 2026, 10:44 PM UTC
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed Mar 21, 2026, 10:01 AM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
  • openFDA reaction terms: Source FDA openFDA | Refreshed Feb 9, 2026, 3:14 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Feb 9, 2026, 3:21 AM UTC
Official (FDA)
Identity: Generic ingredient • No FDA branded products linked
No official FDA brand rows linked yet for this ingredient.
Case-reported brands (openFDA): MSK
Catalog species: Both
Safety (openFDA)
Top reactions: Dog 8 • Cat 3 • View
Case summaries: 7 (showing 7) • View
openFDA reports are unverified and do not prove causation.
Diagnosis Codes

Diagnosis-code mappings are not available for this medication yet.

Counseling and Monitoring Highlights

Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.

Top reaction signals
Regurgitation (1) Peritonitis (1) Gastric ulcer (1) Vomiting (1) Uncomfortable (1) Strabismus (1) Shaking (1) Overdose (1)

Data Sources & Change Log

Every non-trivial field is expected to include provenance and update timestamps.

Official 1 Clinical 0 Manufacturer 0 Marketing 0
Current Field Facts
  • side_effects: Top reported reactions (openFDA): Overdose, Underdose, Emesis, Lethargy (see also Central nervous system depression in 'Neurological'), Accidental exposure, Pa… (Official, 2026-02-12)
Recent Revisions
  • side_effects updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields

Top Reported Reactions (openFDA)

De-duplicated reaction terms grouped by body system from FDA openFDA reports (not verified; does not prove causation).

Digestive
Vomiting (1) • Cat

Showing top 5 for Digestive.

Skin & allergy
Erythema • Dog

Showing top 5 for Skin & allergy.

Neurologic
Tiredness (lethargy) • Dog

Showing top 5 for Neurologic.

Effectiveness
Lack of efficacy - NOS (1) • Cat Lack of efficacy (endoparasite) - hookworm (1) • Dog Lack of efficacy (ectoparasite) - tick NOS (1) • Dog Lack of efficacy (bacteria) - Ehrlichia (1) • Dog

Showing top 5 for Effectiveness.

Other
Uncomfortable (1) • Dog Strabismus (1) • Dog Shaking (1) • Dog Regurgitation (1) • Dog Peritonitis (1) • Dog
Show more (9)
Overdose (1) • Dog Keratoconjunctivitis (1) • Dog Inappropriate defecation (1) • Dog Gastric ulcer (1) • Dog Eye disorder NOS (1) • Dog Accidental exposure (1) • Cat Underdose • Dog Panting • Dog Agitation • Dog

Showing top 5 for Other.

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Adverse Event Case Summaries (openFDA)

These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.

Dog, Retriever - Labrador, Female, 7 year, 28.18 kilogram • Drug: MSK, Oral • Reactions: Vomiting, Regurgitation, Gastric ulcer, Peritonitis • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2023-US-039145
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 7.00 Year
  • Weight: 28.180 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
Reactions Reported:
Vomiting Regurgitation Gastric ulcer Peritonitis
Outcomes: Outcome Unknown

Dog, ['Retriever - Labrador', 'Dog (unknown)'], Female, 14 year, 17.7 kilogram • Drug: MSK, Oral • Reactions: Lack of efficacy (ectoparasite) - tick NOS, Lack of efficacy (bacteria) - Ehrlichia • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2023-US-023225
  • Serious AE: No
  • Treated For AE: No
  • Sex: Female
  • Age: 14.00 Year
  • Weight: 17.700 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
Reactions Reported:
Lack of efficacy (ectoparasite) - tick NOS Lack of efficacy (bacteria) - Ehrlichia
Outcomes: Outcome Unknown

Dog, Bulldog - American, Male, 8.5 year, 23.9 kilogram • Drug: MSK, Unknown, Dose: 1 dose per animal, Frequency: 1 per day • Reactions: Lack of efficacy (endoparasite) - hookworm • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2023-US-021616
  • Serious AE: No
  • Treated For AE: No
  • Sex: Male
  • Age: 8.50 Year
  • Weight: 23.900 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Dose: 1 dose per animal
  • Frequency: 1 per day
Reactions Reported:
Lack of efficacy (endoparasite) - hookworm
Outcomes: Outcome Unknown

Dog, ['Retriever - Labrador', 'Poodle (unspecified)'], Female, 10 year, 24 kilogram • Drug: MSK, Unknown • Reactions: Shaking, Overdose • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2023-US-017281
  • Serious AE: No
  • Treated For AE: No
  • Sex: Female
  • Age: 10.00 Year
  • Weight: 24.000 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Shaking Overdose
Outcomes: Recovered/Normal

Dog, Chihuahua, Male, 13 year, 3.5 kilogram • Drug: MSK, Unknown • Reactions: Eye disorder NOS, Uncomfortable, Inappropriate defecation, Keratoconjunctivitis, Strabismus • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2023-US-001662
  • Serious AE: No
  • Treated For AE: Yes
  • Sex: Male
  • Age: 13.00 Year
  • Weight: 3.500 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Eye disorder NOS Uncomfortable Inappropriate defecation Keratoconjunctivitis Strabismus
Outcomes: Ongoing

Cat, Domestic Shorthair, Male, 11 year, 5.44 kilogram • Drug: MSK, Tablet, chewable, Oral, Dose: 6.25 Milligram per animal, Frequency: 12 per hour • Reactions: Lack of efficacy - NOS • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2016-US-051398
  • Serious AE: No
  • Treated For AE: No
  • Sex: Male
  • Age: 11.00 Year
  • Weight: 5.440 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet, chewable
  • Dose: 6.25 Milligram per animal
  • Frequency: 12 per hour
Reactions Reported:
Lack of efficacy - NOS
Outcomes: Outcome Unknown

Cat, Domestic Shorthair, Male, 2 year, 2.72 kilogram • Drug: MSK, Tablet, chewable, Oral, Dose: 50 Milligram per animal, Frequency: 1 per day • Reactions: Vomiting, Accidental exposure • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2016-US-008444
  • Serious AE: No
  • Treated For AE: No
  • Sex: Male
  • Age: 2.00 Year
  • Weight: 2.720 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet, chewable
  • Dose: 50 Milligram per animal
  • Frequency: 1 per day
Reactions Reported:
Vomiting Accidental exposure
Outcomes: Recovered/Normal

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Overdose Information

No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.

Storage & Handling

No approved storage guidance is linked yet for this ingredient. Use manufacturer packaging and veterinary guidance for handling/storage.

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