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Midazolam

Detailed information about Midazolam

Official label facts Owner quick guide first Marketing clearly labeled
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Reviewed / Updated / Sources

Reviewed: Not available

Updated: February 12, 2026, 10:44 PM UTC

Sources:

Pet Owner Quick Guide

Start here first for the simple next-step summary.

Used for:

Your vet decides this. Here's what owners typically ask/watch for.

What to watch for:

  • Vomiting (1 reports)
  • wobbly/unsteady walking (1 reports)
  • trouble breathing (1 reports)

When to call the vet:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Facial swelling or hives.
  • Blood in vomit or stool.

What to ask your vet today:

  • Is this medicine the right fit for my pet’s current symptoms?
  • Which warning signs mean I should call back right away?
  • How should I handle missed doses or refusal to take the medicine?
Safety & side effects

What to watch:

  • Vomiting
  • wobbly/unsteady walking
  • trouble breathing

Most reported reactions:

  • Vomiting (1 reports)
  • Unsteady walking (ataxia) (1 reports)
  • Trouble breathing (dyspnea) (1 reports)

When to call your vet:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Facial swelling or hives.
Talk to a Vet / Find a Vet Near You Start Symptom Intake

Data freshness: source data appears current.

Latest refresh: Mar 21, 2026, 10:01 a.m.

Data freshness
  • Medication catalog: Source Roxee | Refreshed Feb 12, 2026, 10:44 PM UTC
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed Mar 21, 2026, 10:01 AM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
  • openFDA reaction terms: Source FDA openFDA | Refreshed Mar 16, 2026, 10:05 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Feb 12, 2026, 10:43 PM UTC
Image coming soon
Midazolam

Midazolam

Drug type: Generic ingredient • Generic profile • No FDA branded products linked

Species: Both

Manufacturer: Not available (source)

Quick Facts

Official label facts first, then secondary summaries. Marketing content is separated below.

Species: Both
Manufacturer: Not available

Adverse Reactions

Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.

Tap or hover a reaction to see what it means in plain language.

Tracked signals
32
Reported cases
32
Serious reports
31
Species represented
2
Grouped by Body System
Digestive (4) · Vomiting, Loss of appetite, Haemorrhagic diarrhoea Skin & allergy (1) · Injection site swelling Neurologic (3) · Unsteady walking (ataxia), Tiredness (lethargy), Head tilt - neurological disorder Effectiveness (1) · Lack of efficacy - NOS Other (23) · Trouble breathing (dyspnea), Leucopenia NOS, Injection site skin change NOS
Most Reported Reactions
Reaction Body system Cases Species Serious cases
Digestive 1 Dog 1
Neurologic 1 Cat 1
Other 1 Dog 1
Neurologic 1 Dog 1
Digestive 1 Dog 1
Other 1 Dog 1
Effectiveness 1 Dog 1
Skin & allergy 1 Dog 1

Species coverage: Dog (16) Cat (16)

View detailed reaction table
Reaction Body system Species Seriousness Frequency Reports
Digestive Dog Serious - 1
Neurologic Cat Serious - 1
Other Dog Serious - 1
Neurologic Dog Serious - 1
Digestive Dog Serious - 1
Other Dog Serious - 1
Effectiveness Dog Serious - 1
Skin & allergy Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Cat Non-serious - 1
Other Cat Serious - 1
Neurologic Cat Serious - 1
Other Cat Serious - 1
Digestive Cat Serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Digestive Dog Serious - 1
Other Cat Serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Dog Serious - 1
Source metadata:
Veterinary reference (advanced)

Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.

At a Glance

Quick facts and links to official labeling and safety signals.

Data freshness
  • Medication catalog: Source Roxee | Refreshed Feb 12, 2026, 10:44 PM UTC
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed Mar 21, 2026, 10:01 AM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
  • openFDA reaction terms: Source FDA openFDA | Refreshed Mar 16, 2026, 10:05 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Feb 12, 2026, 10:43 PM UTC
Official (FDA)
Identity: Generic ingredient • No FDA branded products linked
No official FDA brand rows linked yet for this ingredient.
Case-reported brands (openFDA): MSK
Catalog species: Both
Safety (openFDA)
Top reactions: Dog 30 • Cat 18 • View
Case summaries: 11 (showing 8) • View
openFDA reports are unverified and do not prove causation.
Diagnosis Codes

Diagnosis-code mappings are not available for this medication yet.

Counseling and Monitoring Highlights

Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.

Top reaction signals
Vomiting (1) Unsteady walking (ataxia) (1) Trouble breathing (dyspnea) (1) Tiredness (lethargy) (1) Loss of appetite (1) Leucopenia NOS (1) Lack of efficacy - NOS (1) Injection site swelling (1)

Data Sources & Change Log

Every non-trivial field is expected to include provenance and update timestamps.

Official 1 Clinical 0 Manufacturer 0 Marketing 0
Current Field Facts
  • side_effects: Top reported reactions (openFDA): Vomiting, Seizure NOS, Death, Lethargy (see also Central nervous system depression in Neurological), Diarrhoea, Death by euth… (Official, 2026-02-12)
Recent Revisions
  • side_effects updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields

Top Reported Reactions (openFDA)

De-duplicated reaction terms grouped by body system from FDA openFDA reports (not verified; does not prove causation).

Digestive
Vomiting (1) • Dog Loss of appetite (1) • Dog Haemorrhagic diarrhoea (1) • Cat Drooling (1) • Dog

Showing top 5 for Digestive.

Skin & allergy
Injection site swelling (1) • Dog

Showing top 5 for Skin & allergy.

Neurologic
Unsteady walking (1) • Cat Tiredness (1) • Dog Head tilt - neurological disorder (1) • Cat

Showing top 5 for Neurologic.

Effectiveness
Lack of efficacy - NOS (1) • Dog

Showing top 5 for Effectiveness.

Other
Trouble breathing (1) • Dog Leucopenia NOS (1) • Dog Injection site skin change NOS (1) • Dog Injection site inflammation (1) • Dog Injection site granuloma (1) • Dog
Show more (18)
Inappropriate defecation (1) • Cat Hyperthermia (1) • Cat Hyperactivity (1) • Cat Hiding (1) • Cat Head bobbing (1) • Cat Haematuria (1) • Dog Haematemesis (1) • Cat Falling (1) • Dog Faecal incontinence (1) • Dog Excessive chewing, licking and/or grooming (1) • Cat Elevated thyroxine (1) • Cat Dysphoria (1) • Cat Dehydration (1) • Cat Death (1) • Dog Constipation (1) • Cat Anaemia NOS (1) • Cat Adipsia (1) • Cat Abnormal cytology (1) • Dog

Showing top 5 for Other.

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Adverse Event Case Summaries (openFDA)

These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.

Cat, Cat (other), Male, 13 year, 3.49 kilogram • Drug: MSK, Unknown • Reactions: Slow heart rate, Recovery prolonged • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2025-US-055510
  • Serious AE: No
  • Treated For AE: Yes
  • Sex: Male
  • Age: 13.00 Year
  • Weight: 3.490 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Slow heart rate Recovery prolonged
Outcomes: Recovered/Normal

Cat, Maine Coon, Female, 11 year, 4.58 kilogram • Drug: MSK, Unknown • Reactions: Recovery prolonged • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2025-US-055867
  • Serious AE: No
  • Treated For AE: No
  • Sex: Female
  • Age: 11.00 Year
  • Weight: 4.580 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Recovery prolonged
Outcomes: Recovered/Normal

Dog, Crossbred Canine/dog, Male, 10 year, 33.112 kilogram • Drug: MSK, Injection, solution, Intramuscular, Dose: 3 Milligram per animal • Reactions: Urinary incontinence, Faecal incontinence, Tiredness (lethargy), Tremors, Loss of appetite… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-054275
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 10.00 Year
  • Weight: 33.112 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Intramuscular
  • Form: Injection, solution
  • Dose: 3 Milligram per animal
Reactions Reported:
Urinary incontinence Faecal incontinence Tiredness (lethargy) Tremors Loss of appetite Sedation prolonged Leucopenia NOS Lymphopenia Lack of efficacy - NOS Unable to walk Pyuria Haematuria Urinary tract infection
Outcomes: Ongoing

Dog, Crossbred Canine/dog, Female, 13.83 year, 16.329 kilogram • Drug: MSK, Injection, solution, Unknown • Reactions: Falling, Shaking, Drooling, Panting, Vomiting… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-053347
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 13.83 Year
  • Weight: 16.329 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Injection, solution
Reactions Reported:
Falling Shaking Drooling Panting Vomiting Not eating Nystagmus Tachycardia
Outcomes: Ongoing

Cat, Domestic Shorthair, Female, 15 year • Drug: MSK, Unknown • Reactions: Inappropriate defecation, Hyperthermia, Dehydration, Weight loss, Adipsia… • Outcome: Ongoing

  • Report ID: GBR-USFDACVM-2025-GB-000057
  • Serious AE: Yes
  • Treated For AE: No
  • Sex: Female
  • Age: 15.00 Year
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Inappropriate defecation Hyperthermia Dehydration Weight loss Adipsia Loss of appetite Polyuria Urine abnormalities NOS Elevated thyroxine Neutrophilia Anaemia NOS Nausea Stomatitis Lip disorder NOS Haemorrhagic diarrhoea Haematemesis
Outcomes: Ongoing

Dog, Dog (unknown), Unknown • Drug: MSK, Unknown • Reactions: Regurgitation • Outcome: Outcome Unknown

  • Report ID: GBR-USFDACVM-2025-GB-000058
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Unknown
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Regurgitation
Outcomes: Outcome Unknown

Dog, Weimaraner, Female, 16 month, 28.1 kilogram • Drug: MSK, Subcutaneous, Dose: 1.13 mL per animal, Frequency: 1 per day • Reactions: Injection site swelling, Hyperactivity, Abnormal cytology, Injection site skin change NOS, Local swelling… • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-054707
  • Serious AE: Yes
  • Treated For AE: No
  • Sex: Female
  • Age: 16.00 Month
  • Weight: 28.100 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Subcutaneous
  • Dose: 1.13 mL per animal
  • Frequency: 1 per day
Reactions Reported:
Injection site swelling Hyperactivity Abnormal cytology Injection site skin change NOS Local swelling Injection site inflammation Injection site granuloma
Outcomes: Outcome Unknown

Dog, Dog (unknown), Unknown • Drug: MSK, Unknown • Reactions: Regurgitation, Death, Trouble breathing (dyspnea) • Outcome: Died

  • Report ID: GBR-USFDACVM-2025-GB-000059
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Unknown
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Regurgitation Death Trouble breathing (dyspnea)
Outcomes: Died

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Overdose Information

No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.

Storage & Handling

No approved storage guidance is linked yet for this ingredient. Use manufacturer packaging and veterinary guidance for handling/storage.

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