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Roxee Meds Catalog

Estriol Tablets

Medication catalog facts with explicit FDA-approval, off-label, source-limited, and safety context.

Both Catalog complete FDA data linked Rx required Tablet Intervet, Inc. Official label facts Owner quick guide first
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Data freshness

Storefront facts
Catalog refreshed
Apr 16, 2026, 10:01 a.m.

These are the storefront facts Roxee uses on browse cards and quick facts.

FDA applications
FDA application data refreshed
May 5, 2026, 10:00 a.m.

Sponsor, product, and application records imported from Animal Drugs @ FDA.

Safety reports
Safety data refreshed
May 5, 2026, 10:01 a.m.

openFDA reaction terms and case summaries are supporting evidence, not proof of causality.

Source timing details
Source timing details
  • Storefront facts: Source Roxee | Refreshed Apr 16, 2026, 10:01 AM UTC
    The storefront fact projection used for browse cards and quick facts.
  • Animal Drugs @ FDA: Source FDA | Refreshed May 5, 2026, 10:00 AM UTC
    Applications/products are imported from FDA export data.
  • Animal Drugs @ FDA previews: Source FDA | Refreshed Apr 11, 2026, 10:01 AM UTC
    Label highlights/doc links are fetched from FDA preview endpoints.
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed May 5, 2026, 10:00 AM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
  • openFDA reaction terms: Source FDA openFDA | Refreshed May 5, 2026, 10:04 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed May 5, 2026, 10:04 AM UTC

Evidence

Reviewed / Updated / Sources

Reviewed by: Not available

Last reviewed: April 11, 2026

Updated: April 11, 2026, 10:04 AM UTC

Sources:
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Estriol Tablets

Estriol Tablets

Drug type: Generic ingredient • Branded profile • FDA branded products available

Both Tablet Rx required 100% storefront ready

Species: Both

Manufacturer: Intervet, Inc.

Medication Snapshot

Merged from the current Roxee medication system with field-level provenance, freshness, and completeness tracking.

Estriol Tablets

For the control of estrogen-responsive urinary incontinence in ovariohysterectomized female dogs. Species commonly shown: Both, Ovariohysterectomized Females.

Generic name
Estriol Tablets
Brand names
Incurin®, AX Pharmaceutical Corp
Manufacturer
Intervet, Inc.
Species
Both, Ovariohysterectomized Females
Dosage forms
Tablet
Prescription
Prescription required
Completeness
100%
Validation
Complete
Brand names
Incurin® AX Pharmaceutical Corp
Dosage forms
Tablet

Indications / Uses

For the control of estrogen-responsive urinary incontinence in ovariohysterectomized female dogs.

Warnings / Contraindications

Dogs should not receive more than 2 mg Incurin™ Tablets per day (2 tablets). If the dog does not respond to 2 mg of Incurin™ Tablets per day, the diagnosis should be re-assessed. For Oral Use in Dogs Only. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

  • Dogs should not receive more than 2 mg Incurin™ Tablets per day (2 tablets). If the dog does not respond to 2 mg of Incurin™ Tablets per day, the diagnosis should be re-assessed. For Oral Use in Dogs Only. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Side Effects

Top reported reactions (openFDA): Lack of efficacy - NOS, Swollen vulva, Genital tract licking, Vaginal discharge, Death by euthanasia, Decreased appetite.

FAQ

Both, Ovariohysterectomized Females

Yes. Roxee shows this as prescription-only.

Tablet

Related Conditions

Urinary incontinence (spay incontinence, neurogenic)

Source Transparency

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Pet Owner Quick Guide

Start here first for the safest next-step summary before the deeper medication detail.

Used for:

For the control of estrogen-responsive urinary incontinence in ovariohysterectomized female dogs.

Dosing note:

Exact dosing depends on your pet's species, weight, and health status. Use your veterinarian's instructions for the exact dose and schedule.

What to watch for:

  • Dogs should not receive more than 2 mg Incurin™ Tablets per day (2 tablets)
  • If the dog does not respond to 2 mg of Incurin™ Tablets per day, the diagnosis should be re-assessed
  • For Oral Use in Dogs Only
  • Vomiting (1 reports)
  • wobbly/unsteady walking (1 reports)
  • Loss of appetite (1 reports)

When to call the vet:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
  • Facial swelling or hives.
  • Blood in vomit or stool.

Regulatory restrictions are shown in Vet View.

What to tell or ask your vet today:

  • Is this medicine the right fit for my pet’s current symptoms?
  • Which warning signs mean I should call back right away?
  • How should I handle missed doses or refusal to take the medicine?
Major cautions & emergency warning signs

Side effects to monitor:

  • Dogs should not receive more than 2 mg Incurin™ Tablets per day (2 tablets)
  • If the dog does not respond to 2 mg of Incurin™ Tablets per day, the diagnosis should be re-assessed
  • For Oral Use in Dogs Only
  • Vomiting
  • wobbly/unsteady walking

Most reported reactions:

  • Vomiting (1 reports)
  • Unsteady walking (ataxia) (1 reports)
  • Loss of appetite (1 reports)

Emergency warning signs:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
Talk to a Vet / Find a Vet Near You Start Symptom Intake

Quick Facts

Official label facts first, then secondary summaries. Marketing content is separated below.

Species: Both
Manufacturer: Intervet, Inc.
Form: Tablet
Identifiers:
NADA: 141325 NDC Package: 0061-4323-01 NDC Package: 62157-460-01 NDC Product: 0061 NDC Product: 62157
Source metadata:

Warnings / Contraindications

Dogs should not receive more than 2 mg Incurin™ Tablets per day (2 tablets). If the dog does not respond to 2 mg of Incurin™ Tablets per day, the diagnosis should be re-assessed. For Oral Use in Dogs Only. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

  • High: Dogs should not receive more than 2 mg Incurin™ Tablets per day (2 tablets). If the dog does not respond to 2 mg of Incurin™ Tablets per day, the diagnosis should be re-assessed. For Oral Use in Dogs Only. Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Source metadata:

Adverse Reactions

Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.

Tap or hover a reaction to see what it means in plain language.

Tracked signals
32
Reported cases
32
Serious reports
23
Species represented
2
Grouped by Body System
Digestive (4) · Vomiting, Loss of appetite, Diarrhea Skin & allergy (1) · Hair loss NOS Neurologic (2) · Unsteady walking (ataxia), Hind limb ataxia Behavior (2) · Biting -aggression, Behavioral disorder (unspecified) Effectiveness (1) · Lack of efficacy - NOS Other (22) · Intentional misuse, Inappetence, Hyperphosphataemia
Most Reported Reactions
Reaction Body system Cases Species Serious cases
Digestive 1 Dog 1
Neurologic 1 Dog 1
Digestive 1 Dog 1
Other 1 Dog 1
Other 1 Dog 1
Other 1 Dog 1
Other 1 Dog 1
Other 1 Dog 1

Species coverage: Dog (30) Cat (2)

View detailed reaction table
Reaction Body system Species Seriousness Frequency Reports
Digestive Dog Serious - 1
Neurologic Dog Serious - 1
Digestive Dog Serious - 1
Effectiveness Dog Non-serious - 1
Other Dog Non-serious - 1
Other Dog Non-serious - 1
Other Dog Serious - 1
Neurologic Dog Non-serious - 1
Skin & allergy Dog Non-serious - 1
Other Dog Serious - 1
Other Dog Non-serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Digestive Dog Non-serious - 1
Other Dog Serious - 1
Digestive Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Behavior Dog Serious - 1
Behavior Cat Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Non-serious - 1
Other Dog Non-serious - 1
Source metadata:

Documents

Owner handouts and official technical documents open on-page first, with the original source still one click away.

Owner handouts

0
No owner handouts linked yet.

Official label / PI

0
No official label or package insert links yet.

SPL

3

FOI

1

Incurin®

SPL · SPL

Open original
FDA Structured Product Label

Incurin®

Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.

Sponsor
Intervet, Inc.
NADA
141-325
Status
RX
Form
Tablet
Route
Oral
Species
Ovariohysterectomized Females
Composition / specifications
1 mg of estriol per tablet

Dogs

Indication
For the control of estrogen-responsive urinary incontinence in ovariohysterectomized female dogs.
Dosage
The dose of Incurin™ Tablets is not dependent upon body weight. All dogs should receive an initial dose of 2 mg Incurin™ Tablets (2 tablets) orally once per day for a minimum of 14 days. After urinary incontinence is controlled, the lowest effective daily dose of Incurin™ Tablets should be determined by decreasing the dose in a step-wise manner from 2 mg once daily (2 tablets) to 1 mg once daily (1 tablet), then 0.5 mg once daily (1/2 tablet) depending upon the response of the individual dog. There should be a minimum of 7 days between each dose adjustment. After the lowest daily dose that controls urinary incontinence is identified, the dose may be decreased further by administering once every two days.
Limitations
Dogs should not receive more than 2 mg Incurin™ Tablets per day (2 tablets). If the dog does not respond to 2 mg of Incurin™ Tablets per day, the diagnosis should be re-assessed. For Oral Use in Dogs Only. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Incurin SPL

SPL · Structured Product Label

Open original
FDA Structured Product Label XML for Incurin. Use the source link for the full official labeling record.

AX Pharmaceutical Corp SPL

SPL · Structured Product Label

Open original
FDA Structured Product Label XML for AX Pharmaceutical Corp. Use the source link for the full official labeling record.

UCM265609.pdf

FOI · FOI

Open original
Source metadata:
Veterinary reference (advanced)

Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.

At a Glance

Quick facts and links to official labeling and safety signals.

Data freshness
  • Storefront facts: Source Roxee | Refreshed Apr 16, 2026, 10:01 AM UTC
    The storefront fact projection used for browse cards and quick facts.
  • Animal Drugs @ FDA: Source FDA | Refreshed May 5, 2026, 10:00 AM UTC
    Applications/products are imported from FDA export data.
  • Animal Drugs @ FDA previews: Source FDA | Refreshed Apr 11, 2026, 10:01 AM UTC
    Label highlights/doc links are fetched from FDA preview endpoints.
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed May 5, 2026, 10:00 AM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
  • openFDA reaction terms: Source FDA openFDA | Refreshed May 5, 2026, 10:04 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed May 5, 2026, 10:04 AM UTC
Official (FDA)
Identity: Generic ingredient • FDA branded products available
Official FDA brands: AX Pharmaceutical Corp Incurin
Manufacturer mapping: Multiple FDA labelers
Case-reported brands (openFDA): MSK
Catalog species: Both • FDA-labeled species: Ovariohysterectomized Females
Rx/OTC: RX
Form/route: Tablet • Oral
Applications: NADA 141-325
NDC: Packages 0061-4323-01 62157-460-01 • Products 0061 62157
Documents: 1 (FOI: 1) • SPL: 1 • Label highlights • Official documents
Safety (openFDA)
Top reactions: Dog 33 • Cat 0 • View
Case summaries: 6 (showing 6) • View
openFDA reports are unverified and do not prove causation.
Explore
Linked using: Fda_Label (0.95)
Diagnosis Codes

Diagnosis-code mappings are not available for this medication yet.

Counseling and Monitoring Highlights

Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.

Owner-facing counseling points
  • Dogs should not receive more than 2 mg Incurin™ Tablets per day (2 tablets). If the dog does not respond to 2 mg of Incurin™ Tablets per day, the diagnosis should be re-assessed. For Oral Use in Dogs Only. Federal law restricts this drug to use by or on the order of a licensed veterinarian. (Contraindication, High)
Top reaction signals
Vomiting (1) Unsteady walking (ataxia) (1) Loss of appetite (1) Hyperphosphataemia (1) Growling (1) Genital tract licking (1) Generalised weakness (1) Fever (1)

Identifiers & Packages

Normalized identifiers (NDC/NADA/ANADA) and package metadata from regulator listings.

Identifiers
NADA: 141325 NDC Package: 0061-4323-01 NDC Package: 62157-460-01 NDC Product: 0061 NDC Product: 62157
Package NDC Product NDC Form / Route Status
0061-4323-01 0061 -
62157-460-01 62157 -

Enriched Documents

Documents are tiered by source trust: Official, Clinical, Manufacturer, Marketing.

  • Incurin SPL • Structured Product Label • Official
    FDA Structured Product Label from the electronic animal drug product listing directory.
  • AX Pharmaceutical Corp SPL • Structured Product Label • Official
    FDA Structured Product Label from the electronic animal drug product listing directory.
  • UCM265609.pdf • FOI summary • Official • Sept. 21, 2020
    FDA FOI summary for application 141325

Data Sources & Change Log

Every non-trivial field is expected to include provenance and update timestamps.

Official 36 Clinical 1 Manufacturer 0 Marketing 0
Current Field Facts
  • side_effects: Top reported reactions (openFDA): Lack of efficacy - NOS, Swollen vulva, Genital tract licking, Vaginal discharge, Death by euthanasia, Decreased appetite. (Clinical, 2026-04-11)
  • contraindications: Dogs should not receive more than 2 mg Incurin™ Tablets per day (2 tablets). If the dog does not respond to 2 mg of Incurin™ Tablets per day, the diagnosis sho… (Official, 2026-04-12)
  • contraindications: Dogs should not receive more than 2 mg Incurin™ Tablets per day (2 tablets). If the dog does not respond to 2 mg of Incurin™ Tablets per day, the diagnosis sho… (Official, 2026-04-11)
  • indications: For the control of estrogen-responsive urinary incontinence in ovariohysterectomized female dogs. (Official, 2026-05-05)
  • indications: For the control of estrogen-responsive urinary incontinence in ovariohysterectomized female dogs. (Official, 2026-05-03)
  • indications: For the control of estrogen-responsive urinary incontinence in ovariohysterectomized female dogs. (Official, 2026-05-02)
  • indications: For the control of estrogen-responsive urinary incontinence in ovariohysterectomized female dogs. (Official, 2026-04-29)
  • indications: For the control of estrogen-responsive urinary incontinence in ovariohysterectomized female dogs. (Official, 2026-04-28)
  • indications: For the control of estrogen-responsive urinary incontinence in ovariohysterectomized female dogs. (Official, 2026-04-27)
  • indications: For the control of estrogen-responsive urinary incontinence in ovariohysterectomized female dogs. (Official, 2026-04-26)
  • indications: For the control of estrogen-responsive urinary incontinence in ovariohysterectomized female dogs. (Official, 2026-04-25)
  • indications: For the control of estrogen-responsive urinary incontinence in ovariohysterectomized female dogs. (Official, 2026-04-22)
  • manufacturer_name: Multiple FDA labelers (Official, 2026-05-05)
  • manufacturer_name: Multiple FDA labelers (Official, 2026-05-03)
  • manufacturer_name: Multiple FDA labelers (Official, 2026-05-02)
  • manufacturer_name: Multiple FDA labelers (Official, 2026-04-29)
  • manufacturer_name: Multiple FDA labelers (Official, 2026-04-28)
  • manufacturer_name: Multiple FDA labelers (Official, 2026-04-27)
  • manufacturer_name: Multiple FDA labelers (Official, 2026-04-26)
  • manufacturer_name: Multiple FDA labelers (Official, 2026-04-25)
Recent Revisions
  • side_effects updated 2026-04-12 10:05 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-04-12 10:05 by etl_backfill • Backfilled from existing medication fields
  • usage updated 2026-04-12 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-04-11 10:05 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-04-11 10:05 by etl_backfill • Backfilled from existing medication fields
  • usage updated 2026-04-11 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields

FDA Products & Applications (Animal Drugs @ FDA)

Official sponsor/proprietary-name/application-status records linked by active ingredient.

Product Sponsor Application Status Published
Incurin®
RX
estriol
Tablet • Oral
Label highlights
Official documents
Intervet, Inc. NADA 141-325 Approved Sep 21, 2020

Data source: FDA Animal Drugs @ FDA (public search export).

What It's For (FDA Label Highlights)

Extracted from FDA Animal Drugs @ FDA product labeling. Always confirm details with your veterinarian.

Species: Ovariohysterectomized Females
Composition / specifications
1 mg of estriol per tablet
Dogs
Indication
For the control of estrogen-responsive urinary incontinence in ovariohysterectomized female dogs.
Dosage
The dose of Incurin™ Tablets is not dependent upon body weight. All dogs should receive an initial dose of 2 mg Incurin™ Tablets (2 tablets) orally once per day for a minimum of 14 days. After urinary incontinence is controlled, the lowest effective daily dose of Incurin™ Tablets should be determined by decreasing the dose in a step-wise manner from 2 mg once daily (2 tablets) to 1 mg once daily (1 tablet), then 0.5 mg once daily (1/2 tablet) depending upon the response of the individual dog. There should be a minimum of 7 days between each dose adjustment. After the lowest daily dose that controls urinary incontinence is identified, the dose may be decreased further by administering once every two days.
Limitations
Dogs should not receive more than 2 mg Incurin™ Tablets per day (2 tablets). If the dog does not respond to 2 mg of Incurin™ Tablets per day, the diagnosis should be re-assessed. For Oral Use in Dogs Only. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

FDA page: Open in Animal Drugs @ FDA

Usage

For the control of estrogen-responsive urinary incontinence in ovariohysterectomized female dogs.

Source: FDA Animal Drugs @ FDA • Reference

Contraindications

Dogs should not receive more than 2 mg Incurin™ Tablets per day (2 tablets). If the dog does not respond to 2 mg of Incurin™ Tablets per day, the diagnosis should be re-assessed. For Oral Use in Dogs Only. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Top Reported Reactions (openFDA)

De-duplicated reaction terms grouped by body system from FDA openFDA reports (not verified; does not prove causation).

Digestive
Vomiting (1) • Dog Loss of appetite (1) • Dog Diarrhea (1) • Dog Decreased appetite (1) • Dog

Showing top 5 for Digestive.

Skin & allergy
Hair loss NOS (1) • Dog

Showing top 5 for Skin & allergy.

Neurologic
Unsteady walking (1) • Dog Hind limb ataxia (1) • Dog

Showing top 5 for Neurologic.

Behavior
Biting -aggression (1) • Dog Behavioral disorder (1) • Cat

Showing top 5 for Behavior.

Effectiveness
Lack of efficacy - NOS (1) • Dog

Showing top 5 for Effectiveness.

Other
Intentional misuse (1) • Dog Inappetence (1) • Dog Hyperphosphataemia (1) • Dog Growling (1) • Dog Glazed eye (1) • Dog
Show more (17)
Genital tract licking (1) • Dog Generalised weakness (1) • Dog Fever (1) • Dog Elevated serum alkaline phosphatase (1) • Dog Elevated renal parameters (1) • Dog Elevated alanine aminotransferase (1) • Dog Dry mucous membrane (1) • Dog Distension of abdomen (1) • Cat Dehydration (1) • Dog Death by euthanasia (1) • Dog Death (1) • Dog Cough (1) • Dog Cervical pain (1) • Dog Anal sac disorder (1) • Dog Accidental exposure (1) • Dog Abnormal oestrus NOS (1) • Dog Abnormal cytology (1) • Dog

Showing top 5 for Other.

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Adverse Event Case Summaries (openFDA)

These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.

Dog, Terrier - Bull - American Pit, Female, 3 year, 17.463 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Vomiting, Diarrhea, Intentional misuse • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2025-US-075432
  • Serious AE: No
  • Treated For AE: No
  • Sex: Female
  • Age: 3.00 Year
  • Weight: 17.463 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Unassigned
Reactions Reported:
Vomiting Diarrhea Intentional misuse
Outcomes: Recovered/Normal

Dog, Crossbred Canine/dog, Female, 10 year, 41.277 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Death by euthanasia, Accidental exposure, Overdose, Vomiting, Loss of appetite… • Outcome: Euthanized

  • Report ID: USA-USFDACVM-2025-US-075175
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 10.00 Year
  • Weight: 41.277 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Unassigned
Reactions Reported:
Death by euthanasia Accidental exposure Overdose Vomiting Loss of appetite Polydipsia Generalised weakness Tiredness (lethargy) Dry mucous membrane Unsteady walking (ataxia) Vomiting foam Unsteady gait
Outcomes: Euthanized

Dog, ['Crossbred Canine/dog', 'Chihuahua'], Female, 10 year, 6.36 kilogram • Drug: MSK, Tablet, Unknown, Dose: 0.50 Milligram per animal, Frequency: 24 per hour • Reactions: Dehydration, Fever, Decreased appetite • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-075314
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 10.00 Year
  • Weight: 6.360 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Tablet
  • Dose: 0.50 Milligram per animal
  • Frequency: 24 per hour
Reactions Reported:
Dehydration Fever Decreased appetite
Outcomes: Ongoing

Dog, ['Pointing Dog - Hungarian Short-haired (Vizsla)', 'Dog (unknown)'], Female, 14 year, 19.731 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Weakness, Not eating, Glazed eye • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-074579
  • Serious AE: No
  • Treated For AE: No
  • Sex: Female
  • Age: 14.00 Year
  • Weight: 19.731 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Unassigned
Reactions Reported:
Weakness Not eating Glazed eye
Outcomes: Ongoing

Dog, ['Retriever - Labrador', 'Dog (unknown)'], Female, 11 year, 28.304 kilogram • Drug: MSK, Tablet, Unknown • Reactions: Death, Tiredness (lethargy), Vomiting • Outcome: Died

  • Report ID: USA-USFDACVM-2025-US-073880
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 11.00 Year
  • Weight: 28.304 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Tablet
Reactions Reported:
Death Tiredness (lethargy) Vomiting
Outcomes: Died

Dog, ['Collie - Border', 'Dog (unknown)'], Female, 14 year, 20.321 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Tiredness (lethargy), Growling, Biting -aggression, Not himself/herself, Pacing… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-071646
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 14.00 Year
  • Weight: 20.321 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Unassigned
Reactions Reported:
Tiredness (lethargy) Growling Biting -aggression Not himself/herself Pacing Cough Vomiting Regurgitation Weakness Unsteady walking (ataxia) Not eating Elevated alanine aminotransferase Elevated serum alkaline phosphatase Elevated renal parameters Hyperphosphataemia Unable to walk
Outcomes: Ongoing

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Overdose Information

No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.

Storage & Handling

No approved storage guidance is linked yet for this ingredient. Use manufacturer packaging and veterinary guidance for handling/storage.

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