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Meds A-Z

Glucosamine

Detailed information about Glucosamine

Official label facts Owner quick guide first Marketing clearly labeled

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Reviewed / Updated / Sources

Reviewed: Not available

Updated: February 12, 2026, 10:44 PM UTC

Sources:

Pet Owner Quick Guide

Start here first for the simple next-step summary.

Used for:

Your vet decides this. Here's what owners typically ask/watch for.

What to watch for:

  • wobbly/unsteady walking (1 reports)
  • Proprioception deficit (1 reports)
  • Polyuria (1 reports)

When to call the vet:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
  • Facial swelling or hives.
  • Blood in vomit or stool.

What to ask your vet today:

  • Is this medicine the right fit for my pet’s current symptoms?
  • Which warning signs mean I should call back right away?
  • How should I handle missed doses or refusal to take the medicine?
Safety & side effects

What to watch:

  • wobbly/unsteady walking
  • Proprioception deficit
  • Polyuria

Most reported reactions:

  • Unsteady walking (ataxia) (1 reports)
  • Proprioception deficit (1 reports)
  • Polyuria (1 reports)

When to call your vet:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.

Data freshness: source data appears current.

Latest refresh: Mar 21, 2026, 10:01 a.m.

Data freshness
  • Medication catalog: Source Roxee | Refreshed Feb 12, 2026, 10:44 PM UTC
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed Mar 21, 2026, 10:01 AM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
  • openFDA reaction terms: Source FDA openFDA | Refreshed Mar 9, 2026, 10:04 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Feb 24, 2026, 11:07 AM UTC
Image coming soon
Glucosamine

Glucosamine

Drug type: Generic ingredient • Generic profile No FDA branded products linked

Species: Both

Manufacturer: Not available (source)

Quick Facts

Official label facts first, then secondary summaries. Marketing content is separated below.

Species: Both
Manufacturer: Not available
Identifiers:
NDC Package: 16244-1004-1 NDC Package: 45732-013-30 NDC Package: 45732-013-60 NDC Package: 45732-075-10 NDC Package: 73309-352-01 NDC Product: 16244 NDC Product: 45732 NDC Product: 73309

Adverse Reactions

Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.

Tap or hover a reaction to see what it means in plain language.

Tracked signals
32
Reported cases
32
Serious reports
22
Species represented
2
Grouped by Body System
Digestive (2) · Loss of appetite, Diarrhea Neurologic (2) · Unsteady walking (ataxia), Tiredness (lethargy) Behavior (1) · Biting -aggression Effectiveness (1) · Lack of efficacy - NOS Other (26) · Proprioception deficit, Prescribing error, Polyuria
Most Reported Reactions
Reaction Body system Cases Species Serious cases
Neurologic 1 Dog 1
Other 1 Dog 1
Other 1 Cat 1
Other 1 Cat 1
Other 1 Cat 1
Other 1 Dog 1
Other 1 Dog 1
Other 1 Dog 1

Species coverage: Dog (18) Cat (14)

View detailed reaction table
Reaction Body system Species Seriousness Frequency Reports
Neurologic Dog Serious - 1
Neurologic Cat Non-serious - 1
Other Dog Serious - 1
Other Dog Non-serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Dog Serious - 1
Other Dog Non-serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Other Dog Serious - 1
Digestive Cat Non-serious - 1
Other Cat Serious - 1
Other Dog Serious - 1
Other Dog Non-serious - 1
Effectiveness Dog Serious - 1
Other Dog Serious - 1
Other Cat Non-serious - 1
Other Cat Serious - 1
Other Dog Serious - 1
Other Dog Non-serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Dog Non-serious - 1
Digestive Cat Non-serious - 1
Other Dog Serious - 1
Other Cat Non-serious - 1
Behavior Dog Serious - 1
Other Cat Serious - 1
Source metadata:
Veterinary reference (advanced)

Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.

At a Glance

Quick facts and links to official labeling and safety signals.

Data freshness
  • Medication catalog: Source Roxee | Refreshed Feb 12, 2026, 10:44 PM UTC
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed Mar 21, 2026, 10:01 AM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
  • openFDA reaction terms: Source FDA openFDA | Refreshed Mar 9, 2026, 10:04 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Feb 24, 2026, 11:07 AM UTC
Official (FDA)
Identity: Generic ingredient • No FDA branded products linked
No official FDA brand rows linked yet for this ingredient.
Case-reported brands (openFDA): MSK
Catalog species: Both
Safety (openFDA)
Top reactions: Dog 18 Cat 9 View
Case summaries: 11 (showing 8) View
openFDA reports are unverified and do not prove causation.

Diagnosis Codes

Diagnosis-code mappings are not available for this medication yet.

Counseling and Monitoring Highlights

Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.

Top reaction signals
Unsteady walking (ataxia) (1) Proprioception deficit (1) Polyuria (1) Polydipsia (1) Periodontal disorder (1) Pancreatitis NOS (1) Musculoskeletal disorder NOS (1) Medication error NOS (1)

Identifiers & Packages

Normalized identifiers (NDC/NADA/ANADA) and package metadata from regulator listings.

Identifiers
NDC Package: 16244-1004-1 NDC Package: 45732-013-30 NDC Package: 45732-013-60 NDC Package: 45732-075-10 NDC Package: 73309-352-01 NDC Product: 16244 NDC Product: 45732 NDC Product: 73309
Package NDC Product NDC Form / Route Status
16244-1004-1 16244 -
45732-013-30 45732 -
45732-013-60 45732 -
45732-075-10 45732 -
73309-352-01 73309 -

Data Sources & Change Log

Every non-trivial field is expected to include provenance and update timestamps.

Official 1 Clinical 0 Manufacturer 0 Marketing 0
Current Field Facts
  • side_effects: Top reported reactions (openFDA): Vomiting, Lethargy (see also Central nervous system depression in 'Neurological'), Diarrhoea, Death by euthanasia, Seizure NO… (Official, 2026-02-12)
Recent Revisions
  • side_effects updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields

Top Reported Reactions (openFDA)

De-duplicated reaction terms grouped by body system from FDA openFDA reports (not verified; does not prove causation).

Digestive
Loss of appetite (1) • Cat Diarrhea (1) • Cat

Showing top 5 for Digestive.

Neurologic
Unsteady walking (1) • Dog Tiredness (1) • Cat

Showing top 5 for Neurologic.

Behavior
Biting -aggression (1) • Dog

Showing top 5 for Behavior.

Effectiveness
Lack of efficacy - NOS (1) • Dog

Showing top 5 for Effectiveness.

Other
Proprioception deficit (1) • Dog Prescribing error (1) • Dog Polyuria (1) • Cat Polydipsia (1) • Cat Periodontal disorder (1) • Cat
Show more (21)
Pancreatitis NOS (1) • Dog Overdose (1) • Dog Musculoskeletal disorder NOS (1) • Dog Medication error NOS (1) • Dog Malaise (1) • Cat Lymphopenia (1) • Dog Limb weakness (1) • Cat Lick granuloma (1) • Dog Lameness (1) • Dog Knuckling (1) • Dog Hypokalaemia (1) • Cat Hepatopathy (1) • Cat Eosinopenia (1) • Dog Elevated serum alkaline phosphatase (1) • Dog Elevated lipase (1) • Dog Elevated aspartate aminotransferase (1) • Cat Elevated alanine aminotransferase (1) • Cat Disorder of red blood cell NOS (1) • Dog Death by euthanasia (1) • Dog Cough (1) • Cat Abnormal cytology (1) • Cat

Showing top 5 for Other.

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Adverse Event Case Summaries (openFDA)

These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.

Dog, Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog), Female, 14 year, 24.585 kilogram • Drug: MSK, Unassigned, Oral • Reactions: Stiff gait, Walking difficulty, Lameness • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-055204
  • Serious AE: No
  • Treated For AE: No
  • Sex: Female
  • Age: 14.00 Year
  • Weight: 24.585 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Unassigned
Reactions Reported:
Stiff gait Walking difficulty Lameness
Outcomes: Ongoing

Dog, Retriever - Labrador, Male, 14 year, 29.03 kilogram • Drug: MSK, Unassigned, Oral • Reactions: Vomiting, Loss of appetite, Soft stool, Death by euthanasia, Elevated lipase… • Outcome: Euthanized

  • Report ID: USA-USFDACVM-2025-US-053281
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 14.00 Year
  • Weight: 29.030 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Unassigned
Reactions Reported:
Vomiting Loss of appetite Soft stool Death by euthanasia Elevated lipase Pancreatitis NOS Lymphopenia Eosinopenia
Outcomes: Euthanized

Dog, Retriever - Labrador, Male, 4 year, 32.296 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Lick granuloma, Medication error NOS, Lack of efficacy - NOS, Unable to rise, Knuckling… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-053725
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 4.00 Year
  • Weight: 32.296 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Unassigned
Reactions Reported:
Lick granuloma Medication error NOS Lack of efficacy - NOS Unable to rise Knuckling Musculoskeletal disorder NOS Proprioception deficit Unsteady walking (ataxia)
Outcomes: Ongoing

Dog, Boxer (German Boxer), Female, 12 year, 28.123 kilogram • Drug: MSK, Unassigned, Oral • Reactions: Seizure NOS • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-053150
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 12.00 Year
  • Weight: 28.123 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Unassigned
Reactions Reported:
Seizure NOS
Outcomes: Ongoing

Dog, Schnauzer - Miniature, Female, 15 year, 9.34 kilogram • Drug: MSK, Oral • Reactions: Disorder of red blood cell NOS, Elevated serum alkaline phosphatase, Overdose, Prescribing error • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-051256
  • Serious AE: No
  • Treated For AE: No
  • Sex: Female
  • Age: 15.00 Year
  • Weight: 9.340 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
Reactions Reported:
Disorder of red blood cell NOS Elevated serum alkaline phosphatase Overdose Prescribing error
Outcomes: Ongoing

Dog, ['Rottweiler', 'Dog (unknown)'], Female, 9 year, 34.09 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Unable to rise, Biting -aggression, Death by euthanasia, Medication error NOS • Outcome: Euthanized

  • Report ID: USA-USFDACVM-2025-US-051557
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 9.00 Year
  • Weight: 34.090 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Unassigned
Reactions Reported:
Unable to rise Biting -aggression Death by euthanasia Medication error NOS
Outcomes: Euthanized

Cat, Domestic Shorthair, Male, 6 year, 4.853 kilogram • Drug: MSK, Oral, Dose: 1 tablet per animal • Reactions: Cough, Weight loss • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-050804
  • Serious AE: No
  • Treated For AE: No
  • Sex: Male
  • Age: 6.00 Year
  • Weight: 4.853 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Dose: 1 tablet per animal
Reactions Reported:
Cough Weight loss
Outcomes: Outcome Unknown

Cat, Domestic (unspecified), Male, 14 year, 5.91 kilogram • Drug: MSK, Unknown • Reactions: Malaise, Periodontal disorder, Elevated aspartate aminotransferase, Elevated alanine aminotransferase, Elevated serum alkaline phosphatase… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-038382
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 14.00 Year
  • Weight: 5.910 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Malaise Periodontal disorder Elevated aspartate aminotransferase Elevated alanine aminotransferase Elevated serum alkaline phosphatase Proteinuria Vomiting Hepatopathy Polydipsia Polyuria Limb weakness Abnormal cytology
Outcomes: Ongoing

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Overdose Information

No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.

Storage & Handling

No approved storage guidance is linked yet for this ingredient. Use manufacturer packaging and veterinary guidance for handling/storage.

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This medication has not been reviewed by a veterinarian yet.