Medication reference facts with explicit FDA-approval, off-label, source-limited, and safety context. Roxee does not sell, prescribe, or dispense medications.
BothReference completeFDA data linkedRx requiredTabletMultiple FDA sponsors
Official label facts
Owner quick guide first
A source-aware map of what to know, what is uncertain, and what to verify with your veterinarian.
Source Backed Signals
What to know
Evidence-backed contextLimited
Roxee has limited cited overview evidence for Maropitant Citrate; use the official documents and your veterinarian's instructions for product-specific decisions.
Source: openFDA reaction aggregate term
Safety signal coverageReported signals
32 tracked reaction signals; 62 reported cases; 3 serious reports; 2 species groups. These are reporting and label-derived signals for interpretation with a veterinarian.
Source: openFDA reaction aggregate term
Interpretation guardrailNot causation
Adverse-event reports help form a watch list, but they do not prove the medication caused the reaction and they are not a risk ranking between medications.
Evidence tension
Stronger signalLabel / review
Official labels, package inserts, and reviewed summaries carry more weight than isolated reports.
Source: openFDA reaction aggregate term
Weaker signalReported data
Case reports and openFDA terms are useful for pattern awareness, but they are incomplete, can include multiple exposures, and do not estimate an individual pet's probability of harm.
Retriever - Labrador (2), Schnauzer - Miniature (1), Pug (1), ['Mastiff (unspecified)', 'Crossbred Canine/dog'] (1). These are report metadata, not proof that a breed is at higher risk.
What your vet may verify
Fit for this patientVet check
Verify whether Maropitant Citrate fits the pet's species, current diagnosis, age, weight, organ status, pregnancy/lactation status, and concurrent medications.
Evidence limitationsEvidence review
Separate label-backed warnings from adverse-event reports and owner observations before changing the plan.
What to watch next
Watch listOwner-safe
Use caution with severe liver disease, Hepatomegaly, Hypokalaemia, Anaphylaxis
Call sooner ifEscalation
Repeated vomiting or diarrhea. Severe lethargy (hard to wake, very low energy). Collapse or fainting.
Bottom line: Use this Maropitant Citrate brief as a structured watch list and source map, not as a reason to start, stop, or change treatment without your veterinarian.
Lethargy (see also Central nervous system depression in Neurological)VomitingAnorexiaTachycardiaFeverIncreased salivationAbnormal radiograph findingNeurological signs NOSIntentional misuseAgitation
Body systems
NeurologicDigestiveOther
Outcomes
Ongoing
USA-USFDACVM-2026-US-012640
Received 2026-03-16
· MSK
· MSK
Serious
Species
Dog
Breed
Chihuahua
Size / weight
Under 10 lb (2.54 Kilogram)
Age
8+ years (8.25 Year)
Sex
Female Unknown
Region
USA
Reactions
Muscle tremorOpisthotonusRigidity of limbsStar-gazingProlonged anaesthesiaIntentional misuse
Not eatingWalking difficultyPantingSeizure NOSDeathIntentional misuse
Body systems
OtherNeurologic
Outcomes
Died
USA-USFDACVM-2026-US-007418
Received 2026-02-09
· MSK
· MSK
Serious
Species
Cat
Breed
Domestic Shorthair
Size / weight
10-24 lb (8.7 Kilogram)
Age
1-3 years (2.8 Year)
Sex
Male Neutered
Region
USA
Reactions
Lack of efficacy - NOSNot eatingLethargy (see also Central nervous system depression in Neurological)General pain (see other SOCs for specific pain)Facial oedemaTrigeminus paralysisOral ulcerationIntentional misuse
Body systems
EffectivenessOtherNeurologic
Outcomes
Ongoing
USA-USFDACVM-2026-US-003352
Received 2026-01-27
· MSK
· MSK
Serious
Species
Cat
Breed
Domestic Shorthair
Size / weight
Under 10 lb (3.992 Kilogram)
Age
8+ years (13 Year)
Sex
Female Neutered
Region
USA
Reactions
DiarrhoeaDecreased appetiteLethargy (see also Central nervous system depression in Neurological)Bloody diarrhoeaDry mucous membraneOpen mouth breathingUnresponsive to stimuliDecreased haematocritIncreased percentage reticulocytesRegenerative anaemiaIntentional misuseThrombocytopeniaHypersalivationHeart murmur
Body systems
DigestiveNeurologicOther
Outcomes
Ongoing
USA-USFDACVM-2026-US-002976
Received 2026-01-20
· MSK
· MSK
Serious
Species
Dog
Breed
Shih Tzu
Size / weight
Under 10 lb (2.449 Kilogram)
Age
Under 1 year (2 Month)
Sex
Male Intact
Region
USA
Reactions
Lethargy (see also Central nervous system depression in Neurological)VomitingBloody diarrhoeaDiarrhoeaReluctant to moveDecreased body temperaturePale mucous membraneHypoglycaemiaFluid in abdomen NOSFeverDistension of abdomenNeutropeniaLeukocytosis NOSDecreased haematocritNot eatingObtundedHypersalivationAbdominal discomfortDecreased skin turgorBreathing difficultyFlaccid musclesProlonged capillary refill timeRegurgitationLack of efficacy - NOSLymphopeniaMonocytosisLeukopenia NOSHyponatremiaHypercalcaemiaIncreased band neutrophiliaIleusAbnormal radiograph findingIntestinal thickeningHypokalaemiaNasal dischargeIncreased respiratory rateLymphocytosisAbnormal ultrasound findingLateral recumbencyWeak pulseIntentional misuse
Body systems
NeurologicDigestiveOtherEffectiveness
Outcomes
Ongoing
USA-USFDACVM-2025-US-072888
Received 2025-12-11
· MSK
· MSK
Serious
Species
Cat
Breed
Domestic Longhair
Size / weight
10-24 lb (5.715 Kilogram)
Age
8+ years (14 Year)
Sex
Male Neutered
Region
USA
Reactions
SyncopeCollapse NOS (see also Cardio-vascular and Neurological disorders)AnorexiaHidingLow blood pressureHepatomegalyHepato-biliary disorder NOSIntentional misuse
Body systems
OtherNeurologicDigestive
Outcomes
Ongoing
USA-USFDACVM-2025-US-067364
Received 2025-11-14
· MSK
· MSK
Serious
Species
Cat
Breed
Domestic Shorthair
Size / weight
10-24 lb (6.804 Kilogram)
Age
8+ years (14 Year)
Sex
Female Unknown
Region
USA
Reactions
DehydrationEmesis (multiple)Elevated cholesterol (total)Abnormal radiograph findingLack of efficacy - NOSWeaknessUrinary incontinenceAtaxiaDullRecumbencyIncreased coagulation timeElevated aspartate aminotransferase (AST)Elevated creatinineHypokalaemiaElevated gamma-glutamyl transferase (GGT)Elevated triglycerideBlood in urineHypothermiaDisseminated intravascular coagulationCardiorespiratory arrestDeathIntentional misuseShockDistension of abdomen
Body systems
OtherDigestiveEffectivenessNeurologic
Outcomes
Died
USA-USFDACVM-2025-US-067000
Received 2025-11-14
· MSK
· MSK
Serious
Species
Cat
Breed
Domestic Shorthair
Size / weight
Under 10 lb (3.992 Kilogram)
Age
8+ years (13 Year)
Sex
Female Unknown
Region
USA
Reactions
DiarrhoeaDecreased appetiteLethargy (see also Central nervous system depression in Neurological)Bloody diarrhoeaDry mucous membraneOpen mouth breathingUnresponsive to stimuliDecreased haematocritIncreased percentage reticulocytesRegenerative anaemiaIntentional misuseUnderdoseThrombocytopeniaHeart murmurHypersalivation
Body systems
DigestiveNeurologicOther
Outcomes
Ongoing
USA-USFDACVM-2025-US-065982
Received 2025-11-03
· MSK
· MSK
Serious
Species
Dog
Breed
Dachshund (unspecified)
Size / weight
10-24 lb (9.344 Kilogram)
Age
8+ years (14 Year)
Sex
Male Neutered
Region
USA
Reactions
Lethargy (see also Central nervous system depression in Neurological)AnorexiaPale mucous membraneDecreased haematocritThrombocytopeniaImmune mediated haemolytic anaemiaHyperthermiaHeavy breathingFluid in abdomen NOSWeight lossIntentional misuse
Body systems
NeurologicDigestiveOther
Outcomes
Ongoing
Tap or hover a reaction to see what it means in plain language.
Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.
Sponsor
Felix Pharmaceuticals Pvt. Ltd.
ANADA
200-833
Status
RX
Form
Chewable Tablets
Route
Oral
Composition / specifications
16 mg, 24 mg, 60 mg, or 160 mg of maropitant as maropitant citrate per tablet
Dogs
Indication
For the prevention of acute vomiting and the prevention of vomiting due to motion sickness in dogs.
Dosage
For Prevention of Acute Vomiting in dogs 2 - 7 months of age: Administer Maropitant Citrate Tablets orally at a minimum dose of 2 mg/kg (0.9 mg/lb) body weight once daily for up to 5 consecutive days. For Prevention of Acute Vomiting in dogs 7 months of age and older: Administer Maropitant Citrate Tablets orally at a minimum dose of 2 mg/kg (0.9 mg/lb) body weight once daily until resolution of acute vomiting. For Prevention of Vomiting due to motion sickness in dogs 4 months of age and older: Administer Maropitant Citrate Tablets orally at a minimum dose of 8 mg/kg (3.6 mg/lb) body weight once daily for up to 2 consecutive days.
Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.
Sponsor
Felix Pharmaceuticals Pvt. Ltd.
ANADA
200-785
Status
RX
Form
Tablet
Route
Oral
Composition / specifications
16 mg, 24 mg, 60 mg, or 160 mg of maropitant citrate per tablet
Dogs
Indication
For the prevention of acute vomiting and the prevention of vomiting due to motion sickness in dogs.
Dosage
For Prevention of Acute Vomiting in dogs 2 -7 months of age: Administer orally at a minimum dose of 2 mg/kg (0.9 mg/lb) body weight once daily for up to 5 consecutive days.
For Prevention of Acute Vomiting in dogs 7 months of age and older: Administer orally at a minimum dose of 2 mg/kg (0.9 mg/lb) body weight once daily until resolution of acute vomiting.
For Prevention of Vomiting due to motion sickness in dogs 4 months of age and older: Administer orally at a minimum dose of 8 mg/kg (3.6 mg/lb) body weight once daily for up to 2 consecutive days.
Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.
Sponsor
Zoetis Inc.
NADA
141-262
Status
RX
Form
Tablet
Route
Oral
Species
Dog
Composition / specifications
Each tablet contains 16, 24, 60, or 160 milligrams (mg) maropitant as maropitant citrate.
Dogs (7 Months of Age and Older)
Indication
For the prevention of acute vomiting.
Dosage
Administer CERENIA Tablets orally at a minimum dose of 2 mg/kg (0.9 mg/lb) body weight once daily until resolution of acute vomiting.
Limitations
For oral use in dogs only.
Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Dogs (4 Months of Age and Older)
Indication
For the prevention of vomiting due to motion sickness.
Dosage
Administer CERENIA Tablets orally at a minimum dose of 8 mg/kg (3.6 mg/lb) body weight
once daily for up to 2 consecutive days
Limitations
For oral use in dogs only.
Federal law restricts this drug to use by or on the order of a licensed veterinarian.
CERENIA injectable solution should not be used interchangeably with CERENIA tablets for the prevention of vomiting due to motion sickness (8mg/kg).
Dogs (2-7 Months)
Indication
For the prevention of acute vomiting.
Dosage
Administer CERENIA Tablets orally at a minimum dose of 2 mg/kg (0.9 mg/lb) body weight once daily for up to 5 consecutive days
Limitations
For oral use in dogs only.
Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.
Sponsor
Zoetis Inc.
NADA
141-263
Status
RX
Form
Liquid (Solution)
Route
Subcutaneous, Intravenous
Species
Dog • Cat
Composition / specifications
Each milliliter of solution contains 10 milligrams (mg) maropitant as maropitant citrate.
Dogs (2-4 Months of Age)
Indication
For Prevention and Treatment of Acute Vomiting in Dogs:
Dogs 2-4 Months of Age:
Dosage
Administer subcutaneously at 1 mg/kg (0.45 mg/lb) equal to 0.1 mL/kg (0.1 mL/2.2 lb) of body weight once daily for up to 5 consecutive days.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian.
The safe use of CERENIA Injectable Solution has not been evaluated in dogs or cats with gastrointestinal obstruction or that have ingested toxins.
The safe use of CERENIA Injectable Solution has not been evaluated in dogs or cats used for breeding, or in pregnant or lactating bitches or queens.
Dogs (4 Months of Age and Older)
Indication
For Prevention of Vomiting in Dogs 4 months of Age and Older Caused by Emetogenic Medications or Chemotherapeutic Agents.
Dosage
Administer intravenously over 1-2 minutes or subcutaneously at 1 mg/kg (0.45 mg/lb) of body weight one time, 45-60 minutes prior to use of emetogenic medications or chemotherapeutic agents.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian.
The safe use of CERENIA Injectable Solution has not been evaluated in dogs or cats with gastrointestinal obstruction or that have ingested toxins.
The safe use of CERENIA Injectable Solution has not been evaluated in dogs or cats used for breeding, or in pregnant or lactating bitches or queens.
Indication
For Prevention and Treatment of Acute Vomiting in Dogs:
Dogs 2-4 Months of Age:
Dosage
Administer intravenously over 1-2 minutes or subcutaneously at 1 mg/kg (0.45 mg/lb) equal to 0.1 mL/1 kg (1 mL/22 lb) of body weight once daily for up to 5 consecutive days.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian.
The safe use of CERENIA Injectable Solution has not been evaluated in dogs or cats with gastrointestinal obstruction or that have ingested toxins.
The safe use of CERENIA Injectable Solution has not been evaluated in dogs or cats used for breeding, or in pregnant or lactating bitches or queens.
Cats (4 Months of Age and Older)
Indication
For Treatment of Vomiting in Cats 4 Months of Age and Older
Dosage
Administer intravenously over 1-2 minutes or subcutaneously at 1 mg/kg (0.45 mg/lb) equal to 0.1 mL/kg (0.1 mL/2.2 lb) of body weight once daily for up to 5 consecutive days.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian.
The safe use of CERENIA Injectable Solution has not been evaluated in dogs or cats with gastrointestinal obstruction or that have ingested toxins.
The safe use of CERENIA Injectable Solution has not been evaluated in dogs or cats used for breeding, or in pregnant or lactating bitches or queens.
FOI Summary oA 200-833 Approved January 12, 2026.pdf
UCM050060.pdf • FOI summary • Official • Jan. 31, 2019
FDA FOI summary for application 141262
UCM453543.pdf • FOI summary • Official • Jan. 31, 2019
FDA FOI summary for application 141262
ucm062313.pdf • FOI summary • Official • June 1, 2016
FDA FOI summary for application 141263
UCM314825.pdf • FOI summary • Official • June 1, 2016
FDA FOI summary for application 141263
UCM314823.pdf • FOI summary • Official • June 1, 2016
FDA FOI summary for application 141263
UCM484493.pdf • FOI summary • Official • June 1, 2016
FDA FOI summary for application 141263
Data Sources & Change Log
Every non-trivial field is expected to include provenance and update timestamps.
Official 121Clinical 9Manufacturer 0Marketing 0
Current Field Facts
contraindications: Use caution with severe liver disease. (Clinical, 2026-02-12)
overdose_info: Overdose causes excessive drooling, lethargy, collapse due to low BP. Emergency care includes IV fluids, blood pressure support, and monitoring. (Clinical, 2026-04-12)
overdose_info: Overdose causes excessive drooling, lethargy, collapse due to low BP. Emergency care includes IV fluids, blood pressure support, and monitoring. (Clinical, 2026-04-11)
overdose_info: Overdose causes excessive drooling, lethargy, collapse due to low BP. Emergency care includes IV fluids, blood pressure support, and monitoring. (Clinical, 2026-02-12)
side_effects: Pain at injection site, lethargy, diarrhea. (Clinical, 2026-04-11)
storage_handling: Store per label; protect injectable from light. (Clinical, 2026-04-12)
storage_handling: Store per label; protect injectable from light. (Clinical, 2026-04-11)
storage_handling: Store per label; protect injectable from light. (Clinical, 2026-02-12)
usage: Antiemetic used to prevent and treat vomiting (and motion sickness in dogs). (Clinical, 2026-02-12)
contraindications: Use caution with severe liver disease. (Official, 2026-04-12)
contraindications: Use caution with severe liver disease. (Official, 2026-04-11)
indications: Dogs:Â For the prevention and treatment of acute vomiting.Cats:Â For the treatment of vomiting. For the prevention and treatment of acute vomiting in dogs. For… (Official, 2026-08-06)
indications: Dogs:Â For the prevention and treatment of acute vomiting.Cats:Â For the treatment of vomiting. For the prevention and treatment of acute vomiting in dogs. For… (Official, 2026-08-05)
indications: Dogs:Â For the prevention and treatment of acute vomiting.Cats:Â For the treatment of vomiting. For the prevention and treatment of acute vomiting in dogs. For… (Official, 2026-08-04)
indications: Dogs:Â For the prevention and treatment of acute vomiting.Cats:Â For the treatment of vomiting. For the prevention and treatment of acute vomiting in dogs. For… (Official, 2026-08-03)
indications: Dogs:Â For the prevention and treatment of acute vomiting.Cats:Â For the treatment of vomiting. For the prevention and treatment of acute vomiting in dogs. For… (Official, 2026-08-02)
indications: Dogs:Â For the prevention and treatment of acute vomiting.Cats:Â For the treatment of vomiting. For the prevention and treatment of acute vomiting in dogs. For… (Official, 2026-08-01)
indications: Dogs:Â For the prevention and treatment of acute vomiting.Cats:Â For the treatment of vomiting. For the prevention and treatment of acute vomiting in dogs. For… (Official, 2026-07-31)
indications: Dogs:Â For the prevention and treatment of acute vomiting.Cats:Â For the treatment of vomiting. For the prevention and treatment of acute vomiting in dogs. For… (Official, 2026-07-30)
indications: Dogs:Â For the prevention and treatment of acute vomiting.Cats:Â For the treatment of vomiting. For the prevention and treatment of acute vomiting in dogs. For… (Official, 2026-07-29)
Recent Revisions
side_effects updated 2026-04-12 10:05 by etl_backfill • Backfilled from existing medication fields
contraindications updated 2026-04-12 10:05 by etl_backfill • Backfilled from existing medication fields
usage updated 2026-04-12 10:05 by etl_backfill • Backfilled from existing medication fields
side_effects updated 2026-04-11 10:05 by etl_backfill • Backfilled from existing medication fields
contraindications updated 2026-04-11 10:05 by etl_backfill • Backfilled from existing medication fields
usage updated 2026-04-11 10:05 by etl_backfill • Backfilled from existing medication fields
side_effects updated 2026-02-12 19:40 by etl_backfill • Backfilled from existing medication fields
contraindications updated 2026-02-12 19:40 by etl_backfill • Backfilled from existing medication fields
usage updated 2026-02-12 19:40 by etl_backfill • Backfilled from existing medication fields
FDA Products & Applications (Animal Drugs @ FDA)
Official sponsor/proprietary-name/application-status records linked by active ingredient.
Data source: FDA Animal Drugs @ FDA (public search export).
What It's For (FDA Label Highlights)
Extracted from FDA Animal Drugs @ FDA product labeling. Always confirm details with your veterinarian.
Composition / specifications
16 mg, 24 mg, 60 mg, or 160 mg of maropitant as maropitant citrate per tablet
Dogs
Indication
For the prevention of acute vomiting and the prevention of vomiting due to motion sickness in dogs.
Dosage
For Prevention of Acute Vomiting in dogs 2 - 7 months of age: Administer Maropitant Citrate Tablets orally at a minimum dose of 2 mg/kg (0.9 mg/lb) body weight once daily for up to 5 consecutive days. For Prevention of Acute Vomiting in dogs 7 months of age and older: Administer Maropitant Citrate Tablets orally at a minimum dose of 2 mg/kg (0.9 mg/lb) body weight once daily until resolution of acute vomiting. For Prevention of Vomiting due to motion sickness in dogs 4 months of age and older: Administer Maropitant Citrate Tablets orally at a minimum dose of 8 mg/kg (3.6 mg/lb) body weight once daily for up to 2 consecutive days.
16 mg, 24 mg, 60 mg, or 160 mg of maropitant citrate per tablet
Dogs
Indication
For the prevention of acute vomiting and the prevention of vomiting due to motion sickness in dogs.
Dosage
For Prevention of Acute Vomiting in dogs 2 -7 months of age: Administer orally at a minimum dose of 2 mg/kg (0.9 mg/lb) body weight once daily for up to 5 consecutive days.
For Prevention of Acute Vomiting in dogs 7 months of age and older: Administer orally at a minimum dose of 2 mg/kg (0.9 mg/lb) body weight once daily until resolution of acute vomiting.
For Prevention of Vomiting due to motion sickness in dogs 4 months of age and older: Administer orally at a minimum dose of 8 mg/kg (3.6 mg/lb) body weight once daily for up to 2 consecutive days.
Each tablet contains 16, 24, 60, or 160 milligrams (mg) maropitant as maropitant citrate.
Dogs (7 Months of Age and Older)
Indication
For the prevention of acute vomiting.
Dosage
Administer CERENIA Tablets orally at a minimum dose of 2 mg/kg (0.9 mg/lb) body weight once daily until resolution of acute vomiting.
Limitations
For oral use in dogs only.
Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Dogs (4 Months of Age and Older)
Indication
For the prevention of vomiting due to motion sickness.
Dosage
Administer CERENIA Tablets orally at a minimum dose of 8 mg/kg (3.6 mg/lb) body weight
once daily for up to 2 consecutive days
Limitations
For oral use in dogs only.
Federal law restricts this drug to use by or on the order of a licensed veterinarian.
CERENIA injectable solution should not be used interchangeably with CERENIA tablets for the prevention of vomiting due to motion sickness (8mg/kg).
Dogs (2-7 Months)
Indication
For the prevention of acute vomiting.
Dosage
Administer CERENIA Tablets orally at a minimum dose of 2 mg/kg (0.9 mg/lb) body weight once daily for up to 5 consecutive days
Limitations
For oral use in dogs only.
Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Each milliliter of solution contains 10 milligrams (mg) maropitant as maropitant citrate.
Dogs (2-4 Months of Age)
Indication
For Prevention and Treatment of Acute Vomiting in Dogs:
Dogs 2-4 Months of Age:
Dosage
Administer subcutaneously at 1 mg/kg (0.45 mg/lb) equal to 0.1 mL/kg (0.1 mL/2.2 lb) of body weight once daily for up to 5 consecutive days.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian.
The safe use of CERENIA Injectable Solution has not been evaluated in dogs or cats with gastrointestinal obstruction or that have ingested toxins.
The safe use of CERENIA Injectable Solution has not been evaluated in dogs or cats used for breeding, or in pregnant or lactating bitches or queens.
Dogs (4 Months of Age and Older)
Indication
For Prevention of Vomiting in Dogs 4 months of Age and Older Caused by Emetogenic Medications or Chemotherapeutic Agents.
Dosage
Administer intravenously over 1-2 minutes or subcutaneously at 1 mg/kg (0.45 mg/lb) of body weight one time, 45-60 minutes prior to use of emetogenic medications or chemotherapeutic agents.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian.
The safe use of CERENIA Injectable Solution has not been evaluated in dogs or cats with gastrointestinal obstruction or that have ingested toxins.
The safe use of CERENIA Injectable Solution has not been evaluated in dogs or cats used for breeding, or in pregnant or lactating bitches or queens.
Indication
For Prevention and Treatment of Acute Vomiting in Dogs:
Dogs 2-4 Months of Age:
Dosage
Administer intravenously over 1-2 minutes or subcutaneously at 1 mg/kg (0.45 mg/lb) equal to 0.1 mL/1 kg (1 mL/22 lb) of body weight once daily for up to 5 consecutive days.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian.
The safe use of CERENIA Injectable Solution has not been evaluated in dogs or cats with gastrointestinal obstruction or that have ingested toxins.
The safe use of CERENIA Injectable Solution has not been evaluated in dogs or cats used for breeding, or in pregnant or lactating bitches or queens.
Cats (4 Months of Age and Older)
Indication
For Treatment of Vomiting in Cats 4 Months of Age and Older
Dosage
Administer intravenously over 1-2 minutes or subcutaneously at 1 mg/kg (0.45 mg/lb) equal to 0.1 mL/kg (0.1 mL/2.2 lb) of body weight once daily for up to 5 consecutive days.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian.
The safe use of CERENIA Injectable Solution has not been evaluated in dogs or cats with gastrointestinal obstruction or that have ingested toxins.
The safe use of CERENIA Injectable Solution has not been evaluated in dogs or cats used for breeding, or in pregnant or lactating bitches or queens.
De-duplicated reaction terms grouped by body system from FDA openFDA reports (not verified; does not prove causation).
Digestive
Drooling (2) • Dog
Showing top 5 for Digestive.
Skin & allergy
Hives (2) • Dog
Showing top 5 for Skin & allergy.
Effectiveness
Lack of efficacy (endoparasite) - tapeworm (2) • Dog
Showing top 5 for Effectiveness.
Other
Hepatomegaly (4) • Cat
Hypokalaemia (3) • Cat
Anaphylaxis (3) • Dog
Wobbliness (2) • Cat
Vocalisation (2) • Dog
Show more (24)
Unclassifiable adverse event (2) • Dog
Syncope (2) • Cat
Respiratory tract infection NOS (2) • Dog
Reduced globulins (2) • Dog
Not drinking (2) • Dog
Muscle atrophy (2) • Dog
Loose stool (2) • Dog
Local erythema (2) • Dog
Limb non-weight bearing (2) • Dog
Injection site skin discolouration (2) • Dog
Hypoproteinaemia (2) • Dog
Fracture (2) • Dog
Elevated temperature (2) • Dog
Elevated gamma-glutamyl transferase (2) • Cat
Conjunctivitis (2) • Dog
Collapse NOS (2) • Cat
Cardiac enlargement (2) • Cat
Abdominal pain (2) • Cat
Abnormal radiograph finding (1) • Cat
Abnormal posture NOS (1) • Dog
Abnormal histology NOS (1) • Dog
Abnormal cytology (1) • Cat
Abdominal discomfort (1) • Dog
Abdominal cavity disorder NOS (1) • Dog
Showing top 5 for Other.
Data source: FDA openFDA Animal & Veterinary adverse event reports.
Adverse Event Case Summaries (openFDA)
These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.
Neurogenic keratoconjunctivitis siccaCorneal ulcerNasal cavity disorder NOSAbnormal Schirmer tear test
Outcomes: Ongoing
Dog, ['Mastiff (unspecified)', 'Crossbred Canine/dog'], Male, 1 year, 29.574 kilogram • Drug: MSK, Tablet, Oral, Dose: 60 Milligram per animal, Frequency: 1 per day • Reactions: Hypotension, Not eating, Nausea, Drowsiness - systemic disorder, Pain NOS… • Outcome: Euthanized
Report ID: USA-USFDACVM-2026-US-014066
Serious AE: Yes
Treated For AE: Yes
Sex: Male
Age: 1.00 Year
Weight: 29.574 Kilogram
Case-reported brand: MSK
Case-reported manufacturer: MSK
Route: Oral
Form: Tablet
Dose: 60 Milligram per animal
Frequency: 1 per day
Reactions Reported:
HypotensionNot eatingNauseaDrowsiness - systemic disorderPain NOSVomitingRegurgitationDiscoloured urineCoughCrustHyperproteinaemiaHypoalbuminaemiaLeukocytosis NOSNeutrophiliaFluid in abdomen NOSSepticaemiaIntestinal disorder NOSAbdominal cavity disorder NOSElevated lactateAbnormal cytologyDuodenal ulcerIntestinal perforationDeath by euthanasiaLack of efficacy - NOSIntentional misuse
Outcomes: Euthanized
Dog, Male, 12 year, 4.536 kilogram • Drug: MSK, Injection, Subcutaneous, Dose: 4.50 mL per dose, Frequency: 1 per day • Reactions: Lateral recumbency, Agonal breathing, Death • Outcome: Died
Data source: FDA openFDA Animal & Veterinary adverse event reports.
Overdose Information
Overdose causes excessive drooling, lethargy, collapse due to low BP. Emergency care includes IV fluids, blood pressure support, and monitoring.
Storage & Handling
Store per label; protect injectable from light.
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Medical Disclaimer: The medication details provided on Roxee are for informational purposes only and are not a substitute for professional veterinary advice. Always consult your veterinarian about your pet's specific needs.