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Ivermectin 272Mcg, Pyrantel 227Mg

Detailed information about Ivermectin 272Mcg, Pyrantel 227Mg

Official label facts Owner quick guide first Marketing clearly labeled
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Reviewed / Updated / Sources

Reviewed: Not available

Updated: February 12, 2026, 10:44 PM UTC

Sources:

Pet Owner Quick Guide

Start here first for the simple next-step summary.

Used for:

Your vet decides this. Here's what owners typically ask/watch for.

What to watch for:

  • Vomiting (1 reports)
  • very low energy (1 reports)
  • Tenesmus (1 reports)

When to call the vet:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
  • Facial swelling or hives.
  • Blood in vomit or stool.

What to ask your vet today:

  • Is this medicine the right fit for my pet’s current symptoms?
  • Which warning signs mean I should call back right away?
  • How should I handle missed doses or refusal to take the medicine?
Safety & side effects

What to watch:

  • Vomiting
  • very low energy
  • Tenesmus

Most reported reactions:

  • Vomiting (1 reports)
  • Tiredness (lethargy) (1 reports)
  • Tenesmus (1 reports)

When to call your vet:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
Talk to a Vet / Find a Vet Near You Start Symptom Intake

Data freshness: source data appears current.

Latest refresh: Mar 21, 2026, 10:01 a.m.

Data freshness
  • Medication catalog: Source Roxee | Refreshed Feb 12, 2026, 10:44 PM UTC
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed Mar 21, 2026, 10:01 AM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
  • openFDA reaction terms: Source FDA openFDA | Refreshed Feb 9, 2026, 3:15 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Feb 9, 2026, 3:22 AM UTC
Image coming soon
Ivermectin 272Mcg, Pyrantel 227Mg

Ivermectin 272Mcg, Pyrantel 227Mg

Drug type: Generic ingredient • Generic profile • No FDA branded products linked

Species: Both

Manufacturer: Not available (source)

Quick Facts

Official label facts first, then secondary summaries. Marketing content is separated below.

Species: Both
Manufacturer: Not available

Adverse Reactions

Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.

Tap or hover a reaction to see what it means in plain language.

Tracked signals
20
Reported cases
16
Serious reports
0
Species represented
1
Grouped by Body System
Digestive (2) · Vomiting, Diarrhea Skin & allergy (2) · Itching, Alopecia NOS Neurologic (2) · Tiredness (lethargy), Lethargy (see also Central nervous system depression in 'Neurological') Effectiveness (2) · Lack of efficacy (ectoparasite) - flea, Lack of efficacy (endoparasite) - hookworm Other (12) · Tenesmus, Skin irritation, Scooting
Most Reported Reactions
Reaction Body system Cases Species Serious cases
Digestive 1 Dog 0
Neurologic 1 Dog 0
Other 1 Dog 0
Other 1 Dog 0
Other 1 Dog 0
Other 1 Dog 0
Other 1 Dog 0
Effectiveness 1 Dog 0

Species coverage: Dog (20)

View detailed reaction table
Reaction Body system Species Seriousness Frequency Reports
Digestive Dog Non-serious - 1
Neurologic Dog Non-serious - 1
Other Dog Non-serious - 1
Other Dog Non-serious - 1
Other Dog Non-serious - 1
Other Dog Non-serious - 1
Other Dog Non-serious - 1
Effectiveness Dog Non-serious - 1
Skin & allergy Dog Non-serious - 1
Other Dog Non-serious - 1
Other Dog Non-serious - 1
Other Dog Non-serious - 1
Other Dog Non-serious - 1
Other Dog Non-serious - 1
Other Dog Non-serious - 1
Skin & allergy Dog Non-serious - 1
Neurologic Dog Unknown - -
Effectiveness Dog Unknown - -
Other Dog Unknown - -
Digestive Dog Unknown - -
Source metadata:
Veterinary reference (advanced)

Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.

At a Glance

Quick facts and links to official labeling and safety signals.

Data freshness
  • Medication catalog: Source Roxee | Refreshed Feb 12, 2026, 10:44 PM UTC
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed Mar 21, 2026, 10:01 AM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
  • openFDA reaction terms: Source FDA openFDA | Refreshed Feb 9, 2026, 3:15 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Feb 9, 2026, 3:22 AM UTC
Official (FDA)
Identity: Generic ingredient • No FDA branded products linked
No official FDA brand rows linked yet for this ingredient.
Case-reported brands (openFDA): MSK
Catalog species: Both
Safety (openFDA)
Top reactions: Dog 8 • Cat 0 • View
Case summaries: 5 (showing 5) • View
openFDA reports are unverified and do not prove causation.
Diagnosis Codes

Diagnosis-code mappings are not available for this medication yet.

Counseling and Monitoring Highlights

Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.

Top reaction signals
Vomiting (1) Tiredness (lethargy) (1) Tenesmus (1) Skin irritation (1) Scooting (1) Reddening of the skin (1) Overdose (1) Lack of efficacy (ectoparasite) - flea (1)

Data Sources & Change Log

Every non-trivial field is expected to include provenance and update timestamps.

Official 1 Clinical 0 Manufacturer 0 Marketing 0
Current Field Facts
  • side_effects: Top reported reactions (openFDA): INEFFECTIVE, HEARTWORM LARVAE, Vomiting, Lethargy (see also Central nervous system depression in 'Neurological'), Drug dose a… (Official, 2026-02-12)
Recent Revisions
  • side_effects updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields

Top Reported Reactions (openFDA)

De-duplicated reaction terms grouped by body system from FDA openFDA reports (not verified; does not prove causation).

Digestive
Vomiting (1) • Dog Diarrhea • Dog

Showing top 5 for Digestive.

Skin & allergy
Itching (1) • Dog Alopecia NOS (1) • Dog

Showing top 5 for Skin & allergy.

Neurologic
Tiredness (1) • Dog Tiredness (lethargy) • Dog

Showing top 5 for Neurologic.

Effectiveness
Lack of efficacy (ectoparasite) - flea (1) • Dog Lack of efficacy (endoparasite) - hookworm • Dog

Showing top 5 for Effectiveness.

Other
Tenesmus (1) • Dog Skin irritation (1) • Dog Scooting (1) • Dog Reddening of the skin (1) • Dog Overdose (1) • Dog
Show more (7)
INEFFECTIVE, WORMS NOS (1) • Dog INEFFECTIVE, HEARTWORM LARVAE (1) • Dog INEFFECTIVE, ASCARIDS NOS (1) • Dog Inappetence (1) • Dog Excessive licking and/or grooming (1) • Dog Drug dose administration interval too long (1) • Dog Drug dose omission • Dog

Showing top 5 for Other.

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Adverse Event Case Summaries (openFDA)

These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.

Dog, Crossbred Canine/dog, Male, 2 year, 26.308 kilogram • Drug: MSK, Tablet, Oral, Dose: 1 tablet per dose, Frequency: 30 per day • Reactions: INEFFECTIVE, HEARTWORM LARVAE • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2017-US-071147
  • Serious AE: No
  • Treated For AE: Yes
  • Sex: Male
  • Age: 2.00 Year
  • Weight: 26.308 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet
  • Dose: 1 tablet per dose
  • Frequency: 30 per day
Reactions Reported:
INEFFECTIVE, HEARTWORM LARVAE
Outcomes: Outcome Unknown

Dog, Siberian Husky, Female, 2 year, 21.772 kilogram • Drug: MSK, Tablet, Oral, Dose: 1 tablet per dose, Frequency: 1 per day • Reactions: Vomiting, Tiredness (lethargy), Inappetence, INEFFECTIVE, ASCARIDS NOS, Drug dose administration interval too long… • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2017-US-065941
  • Serious AE: No
  • Treated For AE: Yes
  • Sex: Female
  • Age: 2.00 Year
  • Weight: 21.772 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet
  • Dose: 1 tablet per dose
  • Frequency: 1 per day
Reactions Reported:
Vomiting Tiredness (lethargy) Inappetence INEFFECTIVE, ASCARIDS NOS Drug dose administration interval too long Tenesmus Overdose
Outcomes: Outcome Unknown

Dog, Doberman Pinscher, Male, 6.5 year, 33.838 kilogram • Drug: MSK, Tablet, Oral, Dose: 1 tablet per dose, Frequency: 30 per day • Reactions: INEFFECTIVE, HEARTWORM LARVAE • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2017-US-066204
  • Serious AE: No
  • Treated For AE: No
  • Sex: Male
  • Age: 6.50 Year
  • Weight: 33.838 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet
  • Dose: 1 tablet per dose
  • Frequency: 30 per day
Reactions Reported:
INEFFECTIVE, HEARTWORM LARVAE
Outcomes: Outcome Unknown

Dog, Beagle, Male, 9 year, 24.948 kilogram • Drug: MSK, Tablet, Oral, Dose: 1 tablet per dose, Frequency: 1 per month • Reactions: Reddening of the skin, Alopecia NOS, Itching, Skin irritation, Lack of efficacy (ectoparasite) - flea… • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2017-US-065592
  • Serious AE: No
  • Treated For AE: Yes
  • Sex: Male
  • Age: 9.00 Year
  • Weight: 24.948 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet
  • Dose: 1 tablet per dose
  • Frequency: 1 per month
Reactions Reported:
Reddening of the skin Alopecia NOS Itching Skin irritation Lack of efficacy (ectoparasite) - flea Excessive licking and/or grooming
Outcomes: Recovered/Normal

Dog, Retriever - Labrador, Female, 7 year, 39.825 kilogram • Drug: MSK, Tablet, Oral, Dose: 1 tablet per dose, Frequency: 1 per day • Reactions: Scooting, INEFFECTIVE, WORMS NOS • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2017-US-062911
  • Serious AE: No
  • Treated For AE: Yes
  • Sex: Female
  • Age: 7.00 Year
  • Weight: 39.825 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet
  • Dose: 1 tablet per dose
  • Frequency: 1 per day
Reactions Reported:
Scooting INEFFECTIVE, WORMS NOS
Outcomes: Outcome Unknown

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Overdose Information

No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.

Storage & Handling

No approved storage guidance is linked yet for this ingredient. Use manufacturer packaging and veterinary guidance for handling/storage.

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