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Diazepam

Detailed information about Diazepam

Official label facts Owner quick guide first Marketing clearly labeled
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Reviewed / Updated / Sources

Reviewed: Not available

Updated: February 12, 2026, 10:44 PM UTC

Sources:

Pet Owner Quick Guide

Start here first for the simple next-step summary.

Used for:

As a preanesthetic agent to reduce the amount of barbiturate required for short duration anesthesia.

What to watch for:

  • Not for use in dogs with known sensitivity to benzodiazepines
  • Safety in animals intended for breeding and pregnant animals has not been established
  • Vomiting (1 reports)
  • wobbly/unsteady walking (1 reports)
  • Hypernatremia (1 reports)

When to call the vet:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
  • Facial swelling or hives.
  • Blood in vomit or stool.

Regulatory restrictions are shown in Vet View.

What to ask your vet today:

  • Is this medicine the right fit for my pet’s current symptoms?
  • Which warning signs mean I should call back right away?
  • How should I handle missed doses or refusal to take the medicine?
Safety & side effects

What to watch:

  • Not for use in dogs with known sensitivity to benzodiazepines
  • Safety in animals intended for breeding and pregnant animals has not been established
  • Vomiting
  • wobbly/unsteady walking
  • Hypernatremia

Most reported reactions:

  • Vomiting (1 reports)
  • Unsteady walking (ataxia) (1 reports)
  • Hypernatremia (1 reports)

When to call your vet:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
Talk to a Vet / Find a Vet Near You Start Symptom Intake

Data freshness: source data appears current.

Latest refresh: Mar 21, 2026, 10:04 a.m.

Data freshness
  • Medication catalog: Source Roxee | Refreshed Feb 12, 2026, 10:44 PM UTC
  • Animal Drugs @ FDA: Source FDA | Refreshed Mar 21, 2026, 10:01 AM UTC
    Applications/products are imported from FDA export data.
  • Animal Drugs @ FDA previews: Source FDA | Refreshed Feb 9, 2026, 3:05 AM UTC
    Label highlights/doc links are fetched from FDA preview endpoints.
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed Mar 21, 2026, 10:01 AM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
  • openFDA reaction terms: Source FDA openFDA | Refreshed Mar 21, 2026, 10:04 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Feb 9, 2026, 3:22 AM UTC
Image coming soon
Diazepam

Diazepam

Drug type: Generic ingredient • Branded profile • FDA branded products available

Species: Both

Manufacturer: Not available (source)

Quick Facts

Official label facts first, then secondary summaries. Marketing content is separated below.

Species: Both
Manufacturer: Not available
Form: Liquid (Solution)
Identifiers:
NADA: 140848
Source metadata:

Warnings / Contraindications

Not for use in dogs with known sensitivity to benzodiazepines. Safety in animals intended for breeding and pregnant animals has not been established. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

  • High: Not for use in dogs with known sensitivity to benzodiazepines. Safety in animals intended for breeding and pregnant animals has not been established. Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Source metadata:

Adverse Reactions

Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.

Tap or hover a reaction to see what it means in plain language.

Tracked signals
32
Reported cases
32
Serious reports
32
Species represented
2
Grouped by Body System
Digestive (5) · Vomiting, Drooling, Diarrhea Neurologic (1) · Unsteady walking (ataxia) Behavior (1) · Behavioral disorder (unspecified) Other (25) · Hypernatremia, Hyperglycaemia, Hyperchloraemia
Most Reported Reactions
Reaction Body system Cases Species Serious cases
Digestive 1 Dog 1
Neurologic 1 Dog 1
Other 1 Dog 1
Other 1 Dog 1
Other 1 Dog 1
Other 1 Dog 1
Other 1 Dog 1
Other 1 Dog 1

Species coverage: Dog (23) Cat (9)

View detailed reaction table
Reaction Body system Species Seriousness Frequency Reports
Digestive Dog Serious - 1
Neurologic Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Digestive Cat Serious - 1
Other Dog Serious - 1
Digestive Cat Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Digestive Cat Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Digestive Dog Serious - 1
Behavior Cat Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Source metadata:

Documents

Owner handouts and official technical documents are grouped for faster access.

Owner handouts (0)
  • No owner handouts linked yet.
Official label / PI (0)
  • No official label or package insert links yet.
SPL (1)
  • Veteeze® Injection · SPL
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/spl/file/2492/Veteeze%C2%AE%20Injection
FOI (1)
Source metadata:
Veterinary reference (advanced)

Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.

At a Glance

Quick facts and links to official labeling and safety signals.

Data freshness
  • Medication catalog: Source Roxee | Refreshed Feb 12, 2026, 10:44 PM UTC
  • Animal Drugs @ FDA: Source FDA | Refreshed Mar 21, 2026, 10:01 AM UTC
    Applications/products are imported from FDA export data.
  • Animal Drugs @ FDA previews: Source FDA | Refreshed Feb 9, 2026, 3:05 AM UTC
    Label highlights/doc links are fetched from FDA preview endpoints.
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed Mar 21, 2026, 10:01 AM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
  • openFDA reaction terms: Source FDA openFDA | Refreshed Mar 21, 2026, 10:04 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Feb 9, 2026, 3:22 AM UTC
Official (FDA)
Identity: Generic ingredient • FDA branded products available
Official FDA brands: Veteeze® Injection
Case-reported brands (openFDA): MSK
Catalog species: Both • FDA-labeled species: Dog
Rx/OTC: RX
Form/route: Liquid (Solution) • Intravenous
Applications: NADA 140-848
Documents: 1 (FOI: 1) • SPL: 1 • Label highlights • Official documents
Safety (openFDA)
Top reactions: Dog 17 • Cat 12 • View
Case summaries: 10 (showing 8) • View
openFDA reports are unverified and do not prove causation.
Diagnosis Codes

Diagnosis-code mappings are not available for this medication yet.

Counseling and Monitoring Highlights

Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.

Owner-facing counseling points
  • Not for use in dogs with known sensitivity to benzodiazepines. Safety in animals intended for breeding and pregnant animals has not been established. Federal law restricts this drug to use by or on the order of a licensed veterinarian. (Contraindication, High)
Top reaction signals
Vomiting (1) Unsteady walking (ataxia) (1) Hypernatremia (1) Hyperglycaemia (1) Hyperchloraemia (1) Hot spot (1) Gastric ulcer (1) Fluid in abdomen NOS (1)

Identifiers & Packages

Normalized identifiers (NDC/NADA/ANADA) and package metadata from regulator listings.

Identifiers
NADA: 140848

Enriched Documents

Documents are tiered by source trust: Official, Clinical, Manufacturer, Marketing.

Data Sources & Change Log

Every non-trivial field is expected to include provenance and update timestamps.

Official 4 Clinical 0 Manufacturer 0 Marketing 0
Current Field Facts
  • contraindications: Not for use in dogs with known sensitivity to benzodiazepines. Safety in animals intended for breeding and pregnant animals has not been established. Federal l… (Official, 2026-02-12)
  • side_effects: Top reported reactions (openFDA): Seizure NOS, Vomiting, Lethargy (see also Central nervous system depression in 'Neurological'), Death, Death by euthanasia, A… (Official, 2026-02-12)
  • usage: As a preanesthetic agent to reduce the amount of barbiturate required for short duration anesthesia. (Official, 2026-02-12)
Recent Revisions
  • side_effects updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields
  • usage updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields

FDA Products & Applications (Animal Drugs @ FDA)

Official sponsor/proprietary-name/application-status records linked by active ingredient.

Product Sponsor Application Status Published
Veteeze® Injection
RX
Diazepam
Liquid (Solution) • Intravenous
Label highlights
Official documents
Roche Vitamins, Inc. NADA 140-848 W Aug 24, 2017

Data source: FDA Animal Drugs @ FDA (public search export).

What It's For (FDA Label Highlights)

Extracted from FDA Animal Drugs @ FDA product labeling. Always confirm details with your veterinarian.

Species: Dog, No Use Class Stated Or Implied
Composition / specifications
Each milliliter of sterile solution contains 5 milligrams of diazepam.
Dogs
Indication
As a preanesthetic agent to reduce the amount of barbiturate required for short duration anesthesia.
Dosage
Intravenously, 0.2 milligram per kilogram of body weight 3-5 minutes before anesthesia is to be induced using a short acting barbiturate.
Limitations
Not for use in dogs with known sensitivity to benzodiazepines. Safety in animals intended for breeding and pregnant animals has not been established. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

FDA page: Open in Animal Drugs @ FDA

Official Documents (FDA)

Direct links to FDA-hosted PDFs and SPL packages (when available).

Documents
  • Summary

    As a preanesthetic agent to reduce the amount barbiturate required for short duration anesthesia in dogs.

SPL Packages

FDA page: Open in Animal Drugs @ FDA

Usage

As a preanesthetic agent to reduce the amount of barbiturate required for short duration anesthesia.

Source: FDA Animal Drugs @ FDA • Reference

Contraindications

Not for use in dogs with known sensitivity to benzodiazepines. Safety in animals intended for breeding and pregnant animals has not been established. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Top Reported Reactions (openFDA)

De-duplicated reaction terms grouped by body system from FDA openFDA reports (not verified; does not prove causation).

Digestive
Vomiting (1) • Dog Drooling (1) • Cat Diarrhea (1) • Cat Decreased appetite (1) • Cat Bloody diarrhoea (1) • Dog

Showing top 5 for Digestive.

Neurologic
Unsteady walking (1) • Dog

Showing top 5 for Neurologic.

Behavior
Behavioral disorder (1) • Cat

Showing top 5 for Behavior.

Other
Hypernatremia (1) • Dog Hyperglycaemia (1) • Dog Hyperchloraemia (1) • Dog Hot spot (1) • Dog Gastric ulcer (1) • Dog
Show more (20)
Fluid in abdomen NOS (1) • Dog Fever (1) • Dog Elevated blood urea nitrogen (1) • Dog Dry mucous membrane (1) • Dog Drooping eyelid (1) • Dog Dilated pupils (1) • Dog Dermatitis (1) • Dog Dehydration (1) • Dog Dehiscence (1) • Cat Decreased activity (1) • Dog Death (1) • Dog Constricted pupils (1) • Dog Conjunctival oedema (1) • Cat Chattering of teeth (1) • Cat Anaphylaxis (1) • Cat Administration error NOS (1) • Cat Abnormal ultrasound finding (1) • Dog Abnormal pupil light reflex (1) • Dog Abnormal menace reflex test (1) • Dog Abdominal pain (1) • Dog

Showing top 5 for Other.

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Adverse Event Case Summaries (openFDA)

These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.

Dog, ['Collie (unspecified)', 'Dog (unknown)'], Female, 11 year, 18.234 kilogram • Drug: MSK, Unknown • Reactions: Decreased activity, Otitis NOS, Mucous stool, Bloody diarrhoea, Loss of hearing • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-055634
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 11.00 Year
  • Weight: 18.234 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Decreased activity Otitis NOS Mucous stool Bloody diarrhoea Loss of hearing
Outcomes: Ongoing

Dog, Sheepdog - Old English (Bobtail), Male, 4 year, 37.8 kilogram • Drug: MSK, Unknown • Reactions: Malaise, Gastric ulcer, Peritonitis, Fluid in abdomen NOS, Abdominal pain… • Outcome: Euthanized

  • Report ID: DEU-USFDACVM-2025-DE-000039
  • Serious AE: Yes
  • Treated For AE: No
  • Sex: Male
  • Age: 4.00 Year
  • Weight: 37.800 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Malaise Gastric ulcer Peritonitis Fluid in abdomen NOS Abdominal pain Vomiting Abnormal ultrasound finding Death Hyperthermia
Outcomes: Euthanized

Dog, Retriever - Labrador, Male, 6 month, 20.094 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Vomiting, Drooping eyelid, Unsteady walking (ataxia), Dehydration, Abnormal menace reflex test… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-055350
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 6.00 Month
  • Weight: 20.094 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Unassigned
Reactions Reported:
Vomiting Drooping eyelid Unsteady walking (ataxia) Dehydration Abnormal menace reflex test Hyperglycaemia Dilated pupils Seizure NOS Lateral recumbency Strabismus Vertical nystagmus Abnormal pupil light reflex Tremors Dry mucous membrane Injected sclera Wobbliness
Outcomes: Ongoing

Dog, Shepherd Dog - Australian, Female, 10 year, 13.608 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Death, Not eating, Not drinking, Dermatitis, Not himself/herself… • Outcome: Died

  • Report ID: USA-USFDACVM-2025-US-051487
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 10.00 Year
  • Weight: 13.608 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Unassigned
Reactions Reported:
Death Not eating Not drinking Dermatitis Not himself/herself Swollen eye Fever Star-gazing Constricted pupils Trembling Lymphopenia Elevated blood urea nitrogen Hypernatremia Hyperchloraemia Hypokalaemia Medication error NOS Seizure NOS Hot spot
Outcomes: Died

Cat, European, Unknown • Drug: MSK, Intravenous • Reactions: Pharyngeal disorder, Oedema NOS, Anaphylaxis, Conjunctival oedema • Outcome: Recovered/Normal

  • Report ID: DEU-USFDACVM-2025-DE-000033
  • Serious AE: Yes
  • Treated For AE: No
  • Sex: Unknown
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Intravenous
Reactions Reported:
Pharyngeal disorder Oedema NOS Anaphylaxis Conjunctival oedema
Outcomes: Recovered/Normal

Dog, Retriever - Golden, Male, 12 year, 37 kilogram • Drug: MSK, Unknown • Reactions: Lack of efficacy (endoparasite) - hookworm • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-046860
  • Serious AE: No
  • Treated For AE: Yes
  • Sex: Male
  • Age: 12.00 Year
  • Weight: 37.000 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Lack of efficacy (endoparasite) - hookworm
Outcomes: Outcome Unknown

Cat, Domestic Shorthair, Female, 11 year, 4.08 kilogram • Drug: MSK, Intravenous, Dose: 0.20 mL per animal • Reactions: Tiredness (lethargy), Drooling, Dehydration, Loose stool, Decreased appetite… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-047799
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 11.00 Year
  • Weight: 4.080 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Intravenous
  • Dose: 0.20 mL per animal
Reactions Reported:
Tiredness (lethargy) Drooling Dehydration Loose stool Decreased appetite Dehiscence Necrosis NOS Tear flow increased Itching Respiratory signs
Outcomes: Ongoing

Cat, Domestic Shorthair, Male, 7 year, 6.35 kilogram • Drug: MSK, Unknown • Reactions: Tremors, Seizure NOS, Chattering of teeth, Hypothermia, Weakness… • Outcome: Ongoing, Recovered/Normal

  • Report ID: USA-USFDACVM-2025-US-041919
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 7.00 Year
  • Weight: 6.350 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Tremors Seizure NOS Chattering of teeth Hypothermia Weakness Walking difficulty Behavioral disorder (unspecified) Product label issues Mixed Product
Outcomes: Ongoing, Recovered/Normal

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Overdose Information

No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.

Storage & Handling

No approved storage guidance is linked yet for this ingredient. Use manufacturer packaging and veterinary guidance for handling/storage.

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