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Imidacloprid, Flumethrin

Detailed information about Imidacloprid, Flumethrin

Official label facts Owner quick guide first Marketing clearly labeled
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Reviewed / Updated / Sources

Reviewed: Not available

Updated: February 12, 2026, 10:44 PM UTC

Sources:

Pet Owner Quick Guide

Start here first for the simple next-step summary.

Used for:

Your vet decides this. Here's what owners typically ask/watch for.

What to watch for:

  • Scale (1 reports)
  • Polyuria (1 reports)
  • Polydipsia (1 reports)

When to call the vet:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
  • Facial swelling or hives.
  • Blood in vomit or stool.

What to ask your vet today:

  • Is this medicine the right fit for my pet’s current symptoms?
  • Which warning signs mean I should call back right away?
  • How should I handle missed doses or refusal to take the medicine?
Safety & side effects

What to watch:

  • Scale
  • Polyuria
  • Polydipsia

Most reported reactions:

  • Scale (1 reports)
  • Polyuria (1 reports)
  • Polydipsia (1 reports)

When to call your vet:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
Talk to a Vet / Find a Vet Near You Start Symptom Intake

Data freshness: source data appears current.

Latest refresh: Mar 21, 2026, 10:01 a.m.

Data freshness
  • Medication catalog: Source Roxee | Refreshed Feb 12, 2026, 10:44 PM UTC
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed Mar 21, 2026, 10:01 AM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
  • openFDA reaction terms: Source FDA openFDA | Refreshed Feb 9, 2026, 3:15 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Feb 9, 2026, 3:22 AM UTC
Image coming soon
Imidacloprid, Flumethrin

Imidacloprid, Flumethrin

Drug type: Generic ingredient • Generic profile • No FDA branded products linked

Species: Both

Manufacturer: Not available (source)

Quick Facts

Official label facts first, then secondary summaries. Marketing content is separated below.

Species: Both
Manufacturer: Not available

Adverse Reactions

Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.

Tap or hover a reaction to see what it means in plain language.

Tracked signals
28
Reported cases
20
Serious reports
0
Species represented
2
Grouped by Body System
Digestive (1) · Vomiting Skin & allergy (4) · Itching, Hair loss at application site, Hair loss Neurologic (1) · Lethargy (see also Central nervous system depression in Neurological) Behavior (1) · Behavioral disorder (unspecified) Effectiveness (3) · Lack of efficacy (ectoparasite) - flea, Lack of efficacy (bacteria) - Borrelia, Lack of efficacy (ectoparasite) - tick NOS Other (18) · Scale, Polyuria, Polydipsia
Most Reported Reactions
Reaction Body system Cases Species Serious cases
Other 1 Dog 0
Other 1 Dog 0
Other 1 Dog 0
Other 1 Dog 0
Effectiveness 1 Dog 0
Effectiveness 1 Dog 0
Skin & allergy 1 Dog 0
Other 1 Dog 0

Species coverage: Dog (19) Cat (9)

View detailed reaction table
Reaction Body system Species Seriousness Frequency Reports
Other Dog Non-serious - 1
Other Dog Non-serious - 1
Other Dog Non-serious - 1
Other Dog Non-serious - 1
Effectiveness Dog Non-serious - 1
Effectiveness Dog Non-serious - 1
Skin & allergy Dog Non-serious - 1
Other Dog Non-serious - 1
Other Dog Non-serious - 1
Other Dog Non-serious - 1
Skin & allergy Cat Non-serious - 1
Skin & allergy Dog Non-serious - 1
Other Dog Non-serious - 1
Other Dog Non-serious - 1
Other Cat Non-serious - 1
Other Cat Non-serious - 1
Other Cat Non-serious - 1
Other Cat Non-serious - 1
Other Cat Non-serious - 1
Other Dog Non-serious - 1
Digestive Dog Unknown - -
Other Dog Unknown - -
Other Dog Unknown - -
Neurologic Cat Unknown - -
Effectiveness Dog Unknown - -
Other Cat Unknown - -
Behavior Dog Unknown - -
Skin & allergy Cat Unknown - -
Source metadata:
Veterinary reference (advanced)

Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.

At a Glance

Quick facts and links to official labeling and safety signals.

Data freshness
  • Medication catalog: Source Roxee | Refreshed Feb 12, 2026, 10:44 PM UTC
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed Mar 21, 2026, 10:01 AM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
  • openFDA reaction terms: Source FDA openFDA | Refreshed Feb 9, 2026, 3:15 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Feb 9, 2026, 3:22 AM UTC
Official (FDA)
Identity: Generic ingredient • No FDA branded products linked
No official FDA brand rows linked yet for this ingredient.
Case-reported brands (openFDA): MSK
Catalog species: Both
Safety (openFDA)
Top reactions: Dog 8 • Cat 8 • View
Case summaries: 10 (showing 8) • View
openFDA reports are unverified and do not prove causation.
Diagnosis Codes

Diagnosis-code mappings are not available for this medication yet.

Counseling and Monitoring Highlights

Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.

Top reaction signals
Scale (1) Polyuria (1) Polydipsia (1) Ocular discharge (1) Lack of efficacy (ectoparasite) - flea (1) Lack of efficacy (bacteria) - Borrelia (1) Itching (1) Injection site skin discolouration (1)

Data Sources & Change Log

Every non-trivial field is expected to include provenance and update timestamps.

Official 1 Clinical 0 Manufacturer 0 Marketing 0
Current Field Facts
  • side_effects: Top reported reactions (openFDA): Lack of efficacy (ectoparasite) - flea, Lack of efficacy (ectoparasite) - tick NOS, Vomiting, Behavioural disorder NOS, Pruri… (Official, 2026-02-12)
Recent Revisions
  • side_effects updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields

Top Reported Reactions (openFDA)

De-duplicated reaction terms grouped by body system from FDA openFDA reports (not verified; does not prove causation).

Digestive
Vomiting • Dog

Showing top 5 for Digestive.

Skin & allergy
Itching (1) • Dog Hair loss at application site (1) • Cat Hair loss (1) • Dog Application site hair loss • Cat

Showing top 5 for Skin & allergy.

Neurologic
Tiredness (lethargy) • Cat

Showing top 5 for Neurologic.

Behavior
Behavioral disorder • Dog

Showing top 5 for Behavior.

Effectiveness
Lack of efficacy (ectoparasite) - flea (1) • Dog Lack of efficacy (bacteria) - Borrelia (1) • Dog Lack of efficacy (ectoparasite) - tick NOS • Dog

Showing top 5 for Effectiveness.

Other
Scale (1) • Dog Polyuria (1) • Dog Polydipsia (1) • Dog Ocular discharge (1) • Dog Injection site skin discolouration (1) • Dog
Show more (13)
Injection site hair change (1) • Dog Inappropriate schedule of drug administration (1) • Dog Hair coat discolouration (1) • Dog Dermatitis (1) • Dog Application site skin change NOS (1) • Cat Application site scratching (1) • Cat Application site scab (1) • Cat Application site lesion (1) • Cat Application site irritation (1) • Cat Allergy NOS (1) • Dog Scratching • Dog Other abnormal test result NOS • Dog Death • Cat

Showing top 5 for Other.

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Adverse Event Case Summaries (openFDA)

These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.

Dog, Corgi (unspecified), Male, 1 year, 9.979 kilogram • Drug: MSK, Unassigned, Topical • Reactions: Hair loss, Hair coat discolouration, Injection site hair change, Injection site skin discolouration, Inappropriate schedule of drug administration • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-020312
  • Serious AE: No
  • Treated For AE: No
  • Sex: Male
  • Age: 1.00 Year
  • Weight: 9.979 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Topical
  • Form: Unassigned
Reactions Reported:
Hair loss Hair coat discolouration Injection site hair change Injection site skin discolouration Inappropriate schedule of drug administration
Outcomes: Ongoing

Cat, Domestic Mediumhair, Male, 8 year, 3.6 kilogram • Drug: MSK, Unassigned, Unknown, Dose: 1 dose per animal • Reactions: Application site scratching, Application site irritation, Application site lesion • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-024329
  • Serious AE: No
  • Treated For AE: No
  • Sex: Male
  • Age: 8.00 Year
  • Weight: 3.600 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Unassigned
  • Dose: 1 dose per animal
Reactions Reported:
Application site scratching Application site irritation Application site lesion
Outcomes: Ongoing

Dog, ['Retriever - Golden', 'Poodle - Standard'], Male, 5.5 year, 28.123 kilogram • Drug: MSK, Unassigned, Topical, Dose: 1 collar per animal • Reactions: Lack of efficacy (bacteria) - Borrelia • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-024358
  • Serious AE: No
  • Treated For AE: Yes
  • Sex: Male
  • Age: 5.50 Year
  • Weight: 28.123 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Topical
  • Form: Unassigned
  • Dose: 1 collar per animal
Reactions Reported:
Lack of efficacy (bacteria) - Borrelia
Outcomes: Outcome Unknown

Dog, Shepherd Dog - Australian, Female, 11 year, 24.95 kilogram • Drug: MSK, Unassigned, Topical, Dose: 1 collar per animal • Reactions: Lack of efficacy (ectoparasite) - flea, Itching • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-039259
  • Serious AE: No
  • Treated For AE: Yes
  • Sex: Female
  • Age: 11.00 Year
  • Weight: 24.950 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Topical
  • Form: Unassigned
  • Dose: 1 collar per animal
Reactions Reported:
Lack of efficacy (ectoparasite) - flea Itching
Outcomes: Ongoing

Dog, ['Hound (unspecified)', 'Dog (unknown)'], Male, 10 year, 48.07 kilogram • Drug: MSK, Unassigned, Topical, Dose: 1 collar per animal • Reactions: Scale, Dermatitis, Hair loss, Polydipsia, Polyuria… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-020541
  • Serious AE: No
  • Treated For AE: Yes
  • Sex: Male
  • Age: 10.00 Year
  • Weight: 48.070 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Topical
  • Form: Unassigned
  • Dose: 1 collar per animal
Reactions Reported:
Scale Dermatitis Hair loss Polydipsia Polyuria Itching
Outcomes: Ongoing

Dog, Shih Tzu, Female, 6 year, 7.7 kilogram • Drug: MSK, Unassigned, Topical, Dose: 1 collar per animal • Reactions: Ocular discharge, Itching, Allergy NOS, Lack of efficacy (ectoparasite) - flea • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-020707
  • Serious AE: No
  • Treated For AE: Yes
  • Sex: Female
  • Age: 6.00 Year
  • Weight: 7.700 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Topical
  • Form: Unassigned
  • Dose: 1 collar per animal
Reactions Reported:
Ocular discharge Itching Allergy NOS Lack of efficacy (ectoparasite) - flea
Outcomes: Ongoing

Cat, Domestic Shorthair, Unknown, 1 year • Drug: MSK, Unassigned, Topical, Dose: 1 collar per animal • Reactions: Lack of efficacy (ectoparasite) - flea • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-003672
  • Serious AE: No
  • Treated For AE: No
  • Sex: Unknown
  • Age: 1.00 Year
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Topical
  • Form: Unassigned
  • Dose: 1 collar per animal
Reactions Reported:
Lack of efficacy (ectoparasite) - flea
Outcomes: Outcome Unknown

Cat, Domestic Longhair, Unknown, 1 year • Drug: MSK, Unassigned, Topical, Dose: 1 collar per animal • Reactions: Lack of efficacy (ectoparasite) - flea • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-003637
  • Serious AE: No
  • Treated For AE: No
  • Sex: Unknown
  • Age: 1.00 Year
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Topical
  • Form: Unassigned
  • Dose: 1 collar per animal
Reactions Reported:
Lack of efficacy (ectoparasite) - flea
Outcomes: Outcome Unknown

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Overdose Information

No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.

Storage & Handling

No approved storage guidance is linked yet for this ingredient. Use manufacturer packaging and veterinary guidance for handling/storage.

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