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Phenylpropropanolamine Hcl

Detailed information about Phenylpropropanolamine Hcl

Official label facts Owner quick guide first Marketing clearly labeled
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Reviewed / Updated / Sources

Reviewed: Not available

Updated: February 12, 2026, 10:44 PM UTC

Sources:

Pet Owner Quick Guide

Start here first for the simple next-step summary.

Used for:

Your vet decides this. Here's what owners typically ask/watch for.

What to watch for:

  • Weakness (1 reports)
  • Vomiting (1 reports)
  • Urinary retention (1 reports)

When to call the vet:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
  • Facial swelling or hives.
  • Blood in vomit or stool.

What to ask your vet today:

  • Is this medicine the right fit for my pet’s current symptoms?
  • Which warning signs mean I should call back right away?
  • How should I handle missed doses or refusal to take the medicine?
Safety & side effects

What to watch:

  • Weakness
  • Vomiting
  • Urinary retention

Most reported reactions:

  • Weakness (1 reports)
  • Vomiting (1 reports)
  • Urinary retention (1 reports)

When to call your vet:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
Talk to a Vet / Find a Vet Near You Start Symptom Intake

Data freshness: source data appears current.

Latest refresh: Mar 21, 2026, 10:01 a.m.

Data freshness
  • Medication catalog: Source Roxee | Refreshed Feb 12, 2026, 10:44 PM UTC
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed Mar 21, 2026, 10:01 AM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
  • openFDA reaction terms: Source FDA openFDA | Refreshed Mar 15, 2026, 10:05 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Feb 9, 2026, 3:22 AM UTC
Image coming soon
Phenylpropropanolamine Hcl

Phenylpropropanolamine Hcl

Drug type: Generic ingredient • Generic profile • No FDA branded products linked

Species: Both

Manufacturer: Not available (source)

Quick Facts

Official label facts first, then secondary summaries. Marketing content is separated below.

Species: Both
Manufacturer: Not available

Adverse Reactions

Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.

Tap or hover a reaction to see what it means in plain language.

Tracked signals
28
Reported cases
27
Serious reports
24
Species represented
2
Grouped by Body System
Digestive (1) · Vomiting Neurologic (2) · Unsteady walking (ataxia), Tiredness (lethargy) Effectiveness (1) · Lack of efficacy - NOS Other (24) · Weakness, Urinary retention, Urinary incontinence
Most Reported Reactions
Reaction Body system Cases Species Serious cases
Other 1 Dog 1
Digestive 1 Dog 1
Other 1 Dog 1
Neurologic 1 Dog 1
Other 1 Dog 1
Neurologic 1 Cat 1
Other 1 Dog 1
Other 1 Dog 1

Species coverage: Dog (22) Cat (6)

View detailed reaction table
Reaction Body system Species Seriousness Frequency Reports
Other Dog Serious - 1
Digestive Dog Serious - 1
Other Dog Serious - 1
Other Dog Non-serious - 1
Neurologic Dog Serious - 1
Other Dog Serious - 1
Neurologic Cat Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Effectiveness Dog Serious - 1
Other Cat Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Cat Non-serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Other Dog Serious - 1
Other Cat Non-serious - 1
Other Cat Serious - 1
Other Dog Unknown - -
Source metadata:
Veterinary reference (advanced)

Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.

At a Glance

Quick facts and links to official labeling and safety signals.

Data freshness
  • Medication catalog: Source Roxee | Refreshed Feb 12, 2026, 10:44 PM UTC
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed Mar 21, 2026, 10:01 AM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
  • openFDA reaction terms: Source FDA openFDA | Refreshed Mar 15, 2026, 10:05 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Feb 9, 2026, 3:22 AM UTC
Official (FDA)
Identity: Generic ingredient • No FDA branded products linked
No official FDA brand rows linked yet for this ingredient.
Case-reported brands (openFDA): MSK
Catalog species: Both
Safety (openFDA)
Top reactions: Dog 18 • Cat 7 • View
Case summaries: 7 (showing 7) • View
openFDA reports are unverified and do not prove causation.
Diagnosis Codes

Diagnosis-code mappings are not available for this medication yet.

Counseling and Monitoring Highlights

Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.

Top reaction signals
Weakness (1) Vomiting (1) Urinary retention (1) Unsteady walking (ataxia) (1) Underdose (1) Tiredness (lethargy) (1) Stranguria (1) Pacing (1)

Data Sources & Change Log

Every non-trivial field is expected to include provenance and update timestamps.

Official 1 Clinical 0 Manufacturer 0 Marketing 0
Current Field Facts
  • side_effects: Top reported reactions (openFDA): Vomiting, Overdose, Underdose, Lack of efficacy - NOS, Panting, Emesis (multiple). (Official, 2026-02-12)
Recent Revisions
  • side_effects updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields

Top Reported Reactions (openFDA)

De-duplicated reaction terms grouped by body system from FDA openFDA reports (not verified; does not prove causation).

Digestive
Vomiting (1) • Dog

Showing top 5 for Digestive.

Neurologic
Unsteady walking (1) • Dog Tiredness (1) • Cat

Showing top 5 for Neurologic.

Effectiveness
Lack of efficacy - NOS (1) • Dog

Showing top 5 for Effectiveness.

Other
Weakness (1) • Dog Urinary retention (1) • Dog Urinary incontinence (1) • Dog Underdose (1) • Dog Stranguria (1) • Dog
Show more (19)
Pacing (1) • Dog Overdose (1) • Dog Other abnormal test result NOS (1) • Dog Hypothermia (1) • Cat Hypoglycaemia (1) • Dog Hyperphosphataemia (1) • Dog Hyperkalaemia (1) • Dog Foaming at the mouth (1) • Cat Elevated symmetrical dimethylarginine (1) • Dog Elevated serum alkaline phosphatase (1) • Dog Elevated blood urea nitrogen (1) • Dog Elevated alanine aminotransferase (1) • Dog Drug administration duration too long (1) • Dog Death (1) • Dog Bradycardia (1) • Cat Balance problem (1) • Dog Administration error NOS (1) • Cat Accidental exposure (1) • Cat Agitation • Dog

Showing top 5 for Other.

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Adverse Event Case Summaries (openFDA)

These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.

Dog, Doberman Pinscher, Female, 6 year, 43.545 kilogram • Drug: MSK, Tablet, chewable, Oral, Dose: 1 tablet per dose, Frequency: 12 per hour • Reactions: Lack of efficacy - NOS, Death, Other abnormal test result NOS, Underdose, Drug administration duration too long • Outcome: Died

  • Report ID: USA-USFDACVM-2025-US-056129
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 6.00 Year
  • Weight: 43.545 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet, chewable
  • Dose: 1 tablet per dose
  • Frequency: 12 per hour
Reactions Reported:
Lack of efficacy - NOS Death Other abnormal test result NOS Underdose Drug administration duration too long
Outcomes: Died

Dog, Dog (unknown), Female • Drug: MSK, Tablet, chewable, Oral • Reactions: Urinary incontinence • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-056110
  • Serious AE: No
  • Treated For AE: No
  • Sex: Female
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet, chewable
Reactions Reported:
Urinary incontinence
Outcomes: Outcome Unknown

Dog, Chihuahua, Female, 16 year, 4.536 kilogram • Drug: MSK, Tablet, chewable, Oral, Dose: 1 tablet per dose, Frequency: 2 per day • Reactions: Pacing, Vomiting, Tiredness (lethargy), Balance problem, Unsteady walking (ataxia)… • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-051235
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 16.00 Year
  • Weight: 4.536 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet, chewable
  • Dose: 1 tablet per dose
  • Frequency: 2 per day
Reactions Reported:
Pacing Vomiting Tiredness (lethargy) Balance problem Unsteady walking (ataxia) Hyperphosphataemia Elevated blood urea nitrogen Hypoglycaemia Weakness Elevated serum alkaline phosphatase Overdose Hyperkalaemia Elevated alanine aminotransferase Elevated symmetrical dimethylarginine
Outcomes: Outcome Unknown

Dog, Shih Tzu, Female, 13 year, 4.99 kilogram • Drug: MSK, Tablet, chewable, Oral, Dose: 0.50 tablet per dose, Frequency: 12 per hour • Reactions: Urinary retention, Vomiting, Stranguria, Overdose • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-049912
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 13.00 Year
  • Weight: 4.990 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet, chewable
  • Dose: 0.50 tablet per dose
  • Frequency: 12 per hour
Reactions Reported:
Urinary retention Vomiting Stranguria Overdose
Outcomes: Outcome Unknown

Dog, Siberian Husky, Female, 7 year, 31.298 kilogram • Drug: MSK, Tablet, chewable, Oral, Dose: 1 tablet per dose, Frequency: 12 per hour • Reactions: Vomiting, Elevated alanine aminotransferase, Underdose • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-049920
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 7.00 Year
  • Weight: 31.298 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet, chewable
  • Dose: 1 tablet per dose
  • Frequency: 12 per hour
Reactions Reported:
Vomiting Elevated alanine aminotransferase Underdose
Outcomes: Ongoing

Cat, Domestic Shorthair, Female, 16 year • Drug: MSK, Tablet, chewable, Oral, Frequency: 1 per day • Reactions: Foaming at the mouth, Administration error NOS • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2023-US-050503
  • Serious AE: No
  • Treated For AE: No
  • Sex: Female
  • Age: 16.00 Year
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet, chewable
  • Frequency: 1 per day
Reactions Reported:
Foaming at the mouth Administration error NOS
Outcomes: Recovered/Normal

Cat, Domestic Shorthair, Male, 11 year, 3.175 kilogram • Drug: MSK, Tablet, chewable, Oral, Dose: 1 tablet per dose, Frequency: 1 per year • Reactions: Bradycardia, Hypothermia, Tiredness (lethargy), Accidental exposure, Overdose • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2020-US-065384
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 11.00 Year
  • Weight: 3.175 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet, chewable
  • Dose: 1 tablet per dose
  • Frequency: 1 per year
Reactions Reported:
Bradycardia Hypothermia Tiredness (lethargy) Accidental exposure Overdose
Outcomes: Recovered/Normal

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Overdose Information

No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.

Storage & Handling

No approved storage guidance is linked yet for this ingredient. Use manufacturer packaging and veterinary guidance for handling/storage.

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