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Hydromorphone

Detailed information about Hydromorphone

Official label facts Owner quick guide first Marketing clearly labeled
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Reviewed / Updated / Sources

Reviewed: Not available

Updated: February 12, 2026, 10:44 PM UTC

Sources:

Pet Owner Quick Guide

Start here first for the simple next-step summary.

Used for:

Your vet decides this. Here's what owners typically ask/watch for.

What to watch for:

  • wobbly/unsteady walking (1 reports)
  • Loss of appetite (1 reports)
  • Heart murmur (1 reports)

When to call the vet:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
  • Facial swelling or hives.
  • Blood in vomit or stool.

What to ask your vet today:

  • Is this medicine the right fit for my pet’s current symptoms?
  • Which warning signs mean I should call back right away?
  • How should I handle missed doses or refusal to take the medicine?
Safety & side effects

What to watch:

  • wobbly/unsteady walking
  • Loss of appetite
  • Heart murmur

Most reported reactions:

  • Unsteady walking (ataxia) (1 reports)
  • Loss of appetite (1 reports)
  • Heart murmur (1 reports)

When to call your vet:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
Talk to a Vet / Find a Vet Near You Start Symptom Intake

Data freshness: source data appears current.

Latest refresh: Mar 21, 2026, 10:01 a.m.

Data freshness
  • Medication catalog: Source Roxee | Refreshed Feb 12, 2026, 10:44 PM UTC
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed Mar 21, 2026, 10:01 AM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
  • openFDA reaction terms: Source FDA openFDA | Refreshed Mar 4, 2026, 11:04 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Feb 9, 2026, 3:22 AM UTC
Image coming soon
Hydromorphone

Hydromorphone

Drug type: Generic ingredient • Generic profile • No FDA branded products linked

Species: Both

Manufacturer: Not available (source)

Quick Facts

Official label facts first, then secondary summaries. Marketing content is separated below.

Species: Both
Manufacturer: Not available

Adverse Reactions

Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.

Tap or hover a reaction to see what it means in plain language.

Tracked signals
32
Reported cases
32
Serious reports
29
Species represented
2
Grouped by Body System
Digestive (3) · Loss of appetite, Drooling, Decreased appetite Skin & allergy (1) · Facial swelling (possible allergy) Neurologic (3) · Unsteady walking (ataxia), Head tilt - neurological disorder, Grand mal seizure Behavior (2) · Biting -aggression, Behavioral disorder (unspecified) Other (23) · Heart murmur, Head bobbing, Haematemesis
Most Reported Reactions
Reaction Body system Cases Species Serious cases
Neurologic 1 Cat 1
Digestive 1 Cat 1
Other 1 Cat 1
Neurologic 1 Cat 1
Other 1 Cat 1
Other 1 Dog 1
Neurologic 1 Cat 1
Other 1 Cat 1

Species coverage: Cat (22) Dog (10)

View detailed reaction table
Reaction Body system Species Seriousness Frequency Reports
Neurologic Cat Serious - 1
Digestive Cat Serious - 1
Other Cat Serious - 1
Neurologic Cat Serious - 1
Other Cat Serious - 1
Other Dog Serious - 1
Neurologic Cat Serious - 1
Other Cat Serious - 1
Other Cat Non-serious - 1
Skin & allergy Dog Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Digestive Cat Non-serious - 1
Other Cat Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Digestive Dog Serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Dog Serious - 1
Behavior Dog Serious - 1
Behavior Cat Serious - 1
Other Cat Serious - 1
Other Cat Non-serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Source metadata:
Veterinary reference (advanced)

Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.

At a Glance

Quick facts and links to official labeling and safety signals.

Data freshness
  • Medication catalog: Source Roxee | Refreshed Feb 12, 2026, 10:44 PM UTC
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed Mar 21, 2026, 10:01 AM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
  • openFDA reaction terms: Source FDA openFDA | Refreshed Mar 4, 2026, 11:04 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Feb 9, 2026, 3:22 AM UTC
Official (FDA)
Identity: Generic ingredient • No FDA branded products linked
No official FDA brand rows linked yet for this ingredient.
Case-reported brands (openFDA): MSK
Catalog species: Both
Safety (openFDA)
Top reactions: Dog 19 • Cat 14 • View
Case summaries: 10 (showing 8) • View
openFDA reports are unverified and do not prove causation.
Diagnosis Codes

Diagnosis-code mappings are not available for this medication yet.

Counseling and Monitoring Highlights

Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.

Top reaction signals
Unsteady walking (ataxia) (1) Loss of appetite (1) Heart murmur (1) Head tilt - neurological disorder (1) Head bobbing (1) Haematemesis (1) Grand mal seizure (1) Glazed eye (1)

Data Sources & Change Log

Every non-trivial field is expected to include provenance and update timestamps.

Official 1 Clinical 0 Manufacturer 0 Marketing 0
Current Field Facts
  • side_effects: Top reported reactions (openFDA): Vomiting, Death, Injection site swelling, Not eating, Lack of efficacy - NOS, Tachycardia. (Official, 2026-02-12)
Recent Revisions
  • side_effects updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields

Top Reported Reactions (openFDA)

De-duplicated reaction terms grouped by body system from FDA openFDA reports (not verified; does not prove causation).

Digestive
Loss of appetite (1) • Cat Drooling (1) • Cat Decreased appetite (1) • Dog

Showing top 5 for Digestive.

Skin & allergy
Facial swelling (possible allergy) (1) • Dog

Showing top 5 for Skin & allergy.

Neurologic
Unsteady walking (1) • Cat Head tilt - neurological disorder (1) • Cat Grand mal seizure (1) • Cat

Showing top 5 for Neurologic.

Behavior
Biting -aggression (1) • Dog Behavioral disorder (1) • Cat

Showing top 5 for Behavior.

Other
Heart murmur (1) • Cat Head bobbing (1) • Cat Haematemesis (1) • Dog Glazed eye (1) • Cat Fever (1) • Cat
Show more (18)
Excessive chewing, licking and/or grooming (1) • Cat Elevated renal parameters (1) • Cat Dysphoria (1) • Cat Dilated pupils (1) • Cat Dehydration (1) • Dog Dehiscence (1) • Dog Decreased haematocrit (1) • Dog Decreased drinking (1) • Dog Death (1) • Dog Crying (1) • Cat Constipation (1) • Cat Cardiomyopathy (1) • Cat Brain disorder NOS (1) • Cat Bradycardia (1) • Dog Agonal breathing (1) • Cat Agitation (1) • Cat Adipsia (1) • Cat Abnormal menace reflex test (1) • Cat

Showing top 5 for Other.

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Adverse Event Case Summaries (openFDA)

These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.

Dog, Crossbred Canine/dog, Male, 5 month, 10.433 kilogram • Drug: MSK, Unknown • Reactions: Facial swelling (possible allergy), Swollen eyelid, Hypersensitivity reaction • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-052734
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 5.00 Month
  • Weight: 10.433 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Facial swelling (possible allergy) Swollen eyelid Hypersensitivity reaction
Outcomes: Ongoing

Dog, Mixed (Dog), Mixed, 5 year, 3.8 kilogram • Drug: MSK, Intravenous, Dose: 0.05 Milligram per kilogram • Reactions: INEFFECTIVE, ANESTHESIA • Outcome: Recovered/Normal

  • Report ID: KOR-USFDACVM-2025-KR-000003
  • Serious AE: Yes
  • Treated For AE: No
  • Sex: Mixed
  • Age: 5.00 Year
  • Weight: 3.800 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Intravenous
  • Dose: 0.05 Milligram per kilogram
Reactions Reported:
INEFFECTIVE, ANESTHESIA
Outcomes: Recovered/Normal

Dog, Dog (other), Male, 8 year, 7.711 kilogram • Drug: MSK, Unknown, Frequency: 1 per day • Reactions: Overdose, Tarry or black stool, Oral bleeding, Haematemesis, Dehiscence… • Outcome: Died

  • Report ID: USA-USFDACVM-2025-US-052403
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 8.00 Year
  • Weight: 7.711 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Frequency: 1 per day
Reactions Reported:
Overdose Tarry or black stool Oral bleeding Haematemesis Dehiscence Death Bradycardia Decreased haematocrit
Outcomes: Died

Cat, Maine Coon, Male, 3 year, 5.44 kilogram • Drug: MSK, Unknown • Reactions: Unable to walk, Dysphoria, Head bobbing, Excessive chewing, licking and/or grooming, Not eating… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-050195
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 3.00 Year
  • Weight: 5.440 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Unable to walk Dysphoria Head bobbing Excessive chewing, licking and/or grooming Not eating Rolling Lying down Not drinking Hiding Unsteady walking (ataxia) Constipation Vestibular disorder NOS Head tilt - neurological disorder Not himself/herself
Outcomes: Ongoing

Dog, Bulldog - English, Female, 7 month, 16.148 kilogram • Drug: MSK, Injection, solution, Intramuscular • Reactions: Death, Pale mucous membrane, Respiratory arrest • Outcome: Died

  • Report ID: USA-USFDACVM-2025-US-050328
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 7.00 Month
  • Weight: 16.148 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Intramuscular
  • Form: Injection, solution
Reactions Reported:
Death Pale mucous membrane Respiratory arrest
Outcomes: Died

Dog, Terrier - Yorkshire, Male, 1 year, 4.536 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Tiredness (lethargy), Trembling, Decreased appetite, Not drinking, Biting -aggression… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-048901
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 1.00 Year
  • Weight: 4.536 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Unassigned
Reactions Reported:
Tiredness (lethargy) Trembling Decreased appetite Not drinking Biting -aggression Fever Dehydration Shaking Not himself/herself Decreased drinking
Outcomes: Ongoing

Cat, Domestic Shorthair, Male, 15.83 year, 5.49 kilogram • Drug: MSK, Unknown • Reactions: Pyelonephritis, Tiredness (lethargy), Grand mal seizure, Proteinuria, Dysphoria… • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-043133
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 15.83 Year
  • Weight: 5.490 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Pyelonephritis Tiredness (lethargy) Grand mal seizure Proteinuria Dysphoria Weakness Not eating Behavioral disorder (unspecified) Hypothermia Obtunded Hypotension Hypovolaemic shock
Outcomes: Outcome Unknown

Cat, Domestic Longhair, Male, 10 year, 6.66 kilogram • Drug: MSK, Unknown • Reactions: Adipsia, Lateral recumbency, Urinary tract obstruction/blockage, Death, Inappropriate urination… • Outcome: Died

  • Report ID: USA-USFDACVM-2025-US-035176
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 10.00 Year
  • Weight: 6.660 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Adipsia Lateral recumbency Urinary tract obstruction/blockage Death Inappropriate urination Tiredness (lethargy) Loss of appetite Behavioral disorder (unspecified) Glazed eye Hyperglycaemia Elevated renal parameters Hyperexcitation
Outcomes: Died

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Overdose Information

No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.

Storage & Handling

No approved storage guidance is linked yet for this ingredient. Use manufacturer packaging and veterinary guidance for handling/storage.

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