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Thiabendazole

Detailed information about Thiabendazole

Official label facts Owner quick guide first Marketing clearly labeled
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Reviewed / Updated / Sources

Reviewed: Not available

Updated: February 12, 2026, 10:44 PM UTC

Sources:

Pet Owner Quick Guide

Start here first for the simple next-step summary.

Used for:

For control of infections of gastrointestinal roundworms ( Trichostrongylus , Haemonchus Ostertagia , and Cooperia ).

What to watch for:

  • As a single oral dose
  • Milk taken from animals during treatment and within 96 hours (8 milkings) after the latest treatment must not be used for food
  • In severe infections in sheep, treatment should be repeated in 2 to 3 weeks
  • Milk taken from treated animals within 96 hours (8 milkings) after the latest treatment must not be used for food
  • Treatment should be repeated in 2 to 3 weeks
  • Loss of hearing (1 reports)
  • Deafness (1 reports)
  • Vomiting (1 reports)

When to call the vet:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
  • Facial swelling or hives.
  • Blood in vomit or stool.

What to ask your vet today:

  • Is this medicine the right fit for my pet’s current symptoms?
  • Which warning signs mean I should call back right away?
  • How should I handle missed doses or refusal to take the medicine?
Safety & side effects

What to watch:

  • As a single oral dose
  • Milk taken from animals during treatment and within 96 hours (8 milkings) after the latest treatment must not be used for food
  • In severe infections in sheep, treatment should be repeated in 2 to 3 weeks
  • Milk taken from treated animals within 96 hours (8 milkings) after the latest treatment must not be used for food
  • Treatment should be repeated in 2 to 3 weeks

Most reported reactions:

  • Loss of hearing (1 reports)
  • Deafness (1 reports)
  • Vomiting (1 reports)

When to call your vet:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
Talk to a Vet / Find a Vet Near You Start Symptom Intake

Data freshness: source data appears current.

Latest refresh: Mar 21, 2026, 10:01 a.m.

Data freshness
  • Medication catalog: Source Roxee | Refreshed Feb 12, 2026, 10:44 PM UTC
  • Animal Drugs @ FDA: Source FDA | Refreshed Mar 21, 2026, 10:01 AM UTC
    Applications/products are imported from FDA export data.
  • Animal Drugs @ FDA previews: Source FDA | Refreshed Feb 9, 2026, 3:05 AM UTC
    Label highlights/doc links are fetched from FDA preview endpoints.
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed Mar 21, 2026, 10:01 AM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
  • openFDA reaction terms: Source FDA openFDA | Refreshed Mar 14, 2026, 10:07 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Feb 9, 2026, 3:22 AM UTC
Image coming soon
Thiabendazole

Thiabendazole

Drug type: Generic ingredient • Branded profile • FDA branded products available

Species: Both

Manufacturer: Boehringer lngelheim Animal Health USA Inc.

Quick Facts

Official label facts first, then secondary summaries. Marketing content is separated below.

Species: Both
Manufacturer: Boehringer lngelheim Animal Health USA Inc.
Form: Drench, Liquid, Liquid (Solution), Medicated Feed, Medicated Feed Block, Paste
Identifiers:
ANADA: 200565 NADA: 13022 NADA: 13407 NADA: 13954 NADA: 14350 NADA: 15123 NADA: 15875 NADA: 30103 NADA: 30578 NADA: 34114 NADA: 35631 NADA: 37410 NADA: 40205 NADA: 42633 NADA: 42910 NADA: 43141 NADA: 44654 NADA: 47333 NADA: 48487 NADA: 49461
Source metadata:

Warnings / Contraindications

As a single oral dose. Milk taken from animals during treatment and within 96 hours (8 milkings) after the latest treatment must not be used for food. In severe infections in sheep, treatment should be repeated in 2 to 3 weeks. As a single oral dose. Milk taken from animals during treatment and within 96 hours (8 milkings) after the latest treatment must not be used for food. As a single oral dose. Milk taken from treated animals within 96 hours (8 milkings) after the latest treatment must not be used for food. Treatment should be repeated in 2 to 3 weeks.

  • High: As a single oral dose. Milk taken from animals during treatment and within 96 hours (8 milkings) after the latest treatment must not be used for food. In severe infections in sheep, treatment should be repeated in 2 to 3 weeks. As a single oral dose. Milk taken from animals during treatment and within 96 hours (8 milkings) after the latest treatment must not be used for food. As a single oral dose. Milk taken from treated animals within 96 hours (8 milkings) after the latest treatment must not be used for food. Treatment should be repeated in 2 to 3 weeks.
Source metadata:

Adverse Reactions

Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.

Tap or hover a reaction to see what it means in plain language.

Tracked signals
26
Reported cases
26
Serious reports
2
Species represented
2
Grouped by Body System
Digestive (3) · Vomiting, Loss of appetite, Decreased appetite Neurologic (2) · Unsteady walking (ataxia), Tiredness (lethargy) Effectiveness (2) · Lack of efficacy - NOS, Lack of efficacy (fungi) - NOS Other (19) · Vocalisation, Tympanic alteration, Scratching
Most Reported Reactions
Reaction Body system Cases Species Serious cases
Other 1 Cat 1
Other 1 Dog 1
Digestive 1 Cat 0
Other 1 Dog 0
Neurologic 1 Cat 0
Other 1 Cat 0
Neurologic 1 Cat 0
Other 1 Dog 0

Species coverage: Cat (14) Dog (12)

View detailed reaction table
Reaction Body system Species Seriousness Frequency Reports
Digestive Cat Non-serious - 1
Other Dog Non-serious - 1
Neurologic Cat Non-serious - 1
Other Cat Non-serious - 1
Neurologic Cat Non-serious - 1
Other Dog Non-serious - 1
Other Cat Non-serious - 1
Other Dog Non-serious - 1
Other Dog Non-serious - 1
Other Cat Non-serious - 1
Other Dog Non-serious - 1
Other Cat Non-serious - 1
Other Cat Non-serious - 1
Other Cat Serious - 1
Digestive Cat Non-serious - 1
Other Dog Non-serious - 1
Effectiveness Dog Non-serious - 1
Effectiveness Dog Non-serious - 1
Other Cat Non-serious - 1
Other Dog Non-serious - 1
Other Dog Non-serious - 1
Digestive Cat Non-serious - 1
Other Dog Serious - 1
Other Dog Non-serious - 1
Other Cat Non-serious - 1
Other Cat Non-serious - 1
Source metadata:

Documents

Owner handouts and official technical documents are grouped for faster access.

Owner handouts (0)
  • No owner handouts linked yet.
Official label / PI (0)
  • No official label or package insert links yet.
SPL (24)
  • E-Z-EX Wormer Mintrate Block · SPL
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/spl/file/787/E-Z-EX%20Wormer%20Mintrate%20Block
  • E-Z-EX Wormer Pellets · SPL
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/spl/file/1153/E-Z-EX%20Wormer%20Pellets
  • Equizole® · SPL
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/spl/file/377/Equizole%C2%AE
  • Equizole® 50% Wormer Paste For Horses · SPL
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/spl/file/2526/Equizole%C2%AE%2050%25%20Wormer%20Paste%20For%20Horses
  • Equizole® 50% Wormer Paste · SPL
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/spl/file/2525/Equizole%C2%AE%2050%25%20Wormer%20Paste
  • Equizole® A · SPL
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/spl/file/431/Equizole%C2%AE%20A
  • Equizole® A Liquid · SPL
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/spl/file/891/Equizole%C2%AE%20A%20Liquid
  • Equizole® Horse Wormer · SPL
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/spl/file/1671/Equizole%C2%AE%20Horse%20Wormer
  • Equizole® Horse Wormer Pellets · SPL
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/spl/file/811/Equizole%C2%AE%20Horse%20Wormer%20Pellets
  • Omnizole · SPL
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/spl/file/1692/Omnizole
  • TBZ 200 Medicated Feed Premix · SPL
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/spl/file/1715/TBZ%20200%20Medicated%20Feed%20Premix
  • TBZ® Cattle Wormer (Drench) · SPL
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/spl/file/1698/TBZ%C2%AE%20Cattle%20Wormer%20%28Drench%29
  • TBZ® Wormer Paste 43% · SPL
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/spl/file/949/TBZ%C2%AE%20Wormer%20Paste%2043%25
  • TBZ® Wormer Paste 50% · SPL
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/spl/file/919/TBZ%C2%AE%20Wormer%20Paste%2050%25
  • Thibenzole (18 mg) · SPL
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/spl/file/1720/Thibenzole%20%2818%20mg%29
  • Thibenzole 20% Swine Premix · SPL
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/spl/file/1642/Thibenzole%2020%25%20Swine%20Premix
  • Thibenzole 300 Medicated · SPL
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/spl/file/790/Thibenzole%20300%20Medicated
  • Thibenzole Pig Wormer · SPL
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/spl/file/418/Thibenzole%20Pig%20Wormer
  • Thibenzole Sheep & Goat Wormer · SPL
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/spl/file/1651/Thibenzole%20Sheep%20%26%20Goat%20Wormer
  • Purina® Horse Wormer Medicated · SPL
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/spl/file/11/Purina%C2%AE%20Horse%20Wormer%20Medicated
  • Equizole®-B · SPL
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/spl/file/1290/Equizole%C2%AE-B
  • Equivet-14 · SPL
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/spl/file/1289/Equivet-14
  • Thiabendazole, Dexamethasone, Neomycin Sulfate Solution · SPL
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/spl/file/2271/Thiabendazole%2C%20Dexamethasone%2C%20Neomycin%20Sulfate%20Solution
  • Tresaderm Dermatologic Solution · SPL
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/spl/file/794/Tresaderm%20Dermatologic%20Solution
FOI (2)
  • UCM452230.pdf · FOI
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/document/downloadFoi/295
  • UCM457231.pdf · FOI
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/document/downloadFoi/1245
Source metadata:
Veterinary reference (advanced)

Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.

At a Glance

Quick facts and links to official labeling and safety signals.

Data freshness
  • Medication catalog: Source Roxee | Refreshed Feb 12, 2026, 10:44 PM UTC
  • Animal Drugs @ FDA: Source FDA | Refreshed Mar 21, 2026, 10:01 AM UTC
    Applications/products are imported from FDA export data.
  • Animal Drugs @ FDA previews: Source FDA | Refreshed Feb 9, 2026, 3:05 AM UTC
    Label highlights/doc links are fetched from FDA preview endpoints.
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed Mar 21, 2026, 10:01 AM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
  • openFDA reaction terms: Source FDA openFDA | Refreshed Mar 14, 2026, 10:07 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Feb 9, 2026, 3:22 AM UTC
Official (FDA)
Identity: Generic ingredient • FDA branded products available
Official FDA brands: E-Z-EX Wormer Mintrate Block E-Z-EX Wormer Pellets Equizole® Equizole® 50% Wormer Paste For Horses Equizole® 50% Wormer Paste Equizole® A Equizole® A Liquid Equizole® Horse Wormer Equizole® Horse Wormer Pellets Equizole®-B Equivet-14 Omnizole Purina® Horse Wormer Medicated TBZ 200 Medicated Feed Premix TBZ® Cattle Wormer (Drench) TBZ® Wormer Paste 43% TBZ® Wormer Paste 50% Thiabendazole, Dexamethasone, Neomycin Sulfate Solution Thibenzole (18 mg) Thibenzole 20% Swine Premix Thibenzole 300 Medicated Thibenzole Pig Wormer Thibenzole Sheep & Goat Wormer Tresaderm Dermatologic Solution
Case-reported brands (openFDA): MSK
Catalog species: Both • FDA-labeled species: 1 to 8 weeks of age, Cat, Dog, Goat, Horse, No Use Class Stated Or Implied, No use class stated or implied, Pasture, Pheasant, Sheep
Rx/OTC: OTC, RX
Form/route: Drench, Liquid, Liquid (Solution), Medicated Feed, Medicated Feed Block, Paste, Pellet, Solution, Suspension, Top Dressing In Feed • Nasogastric, Oral, Topical
Applications: NADA 42910 • NADA 30578 • NADA 34114 • NADA 98689 • NADA 37410 • NADA 47333 • NADA 13407 • NADA 44654 • NADA 14350 • NADA 15875 • NADA 15123 • NADA 49461 • NADA 48487 • NADA 30103 • NADA 13954 • NADA 43141 • NADA 35631 • NADA 13022 • NADA 40205 • NADA 91067 • ANADA 200-565 • NADA 42633
Documents: 2 (FOI: 2) • SPL: 24 • Label highlights • Official documents
Safety (openFDA)
Top reactions: Dog 7 • Cat 17 • View
Case summaries: 10 (showing 8) • View
openFDA reports are unverified and do not prove causation.
Explore
Linked using: Fda_Label (0.95), Fda_Label (0.95)
Diagnosis Codes
ICD10_CM: H60.90
Otitis externa, unspecified ear

Counseling and Monitoring Highlights

Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.

Owner-facing counseling points
  • As a single oral dose. Milk taken from animals during treatment and within 96 hours (8 milkings) after the latest treatment must not be used for food. In severe infections in sheep, treatment should be repeated in 2 to 3 weeks. As a single oral dose. Milk taken from animals during treatment and within 96 hours (8 milkings) after the latest treatment must not be used for food. As a single oral dose. Milk taken from treated animals within 96 hours (8 milkings) after the latest treatment must not be used for food. Treatment should be repeated in 2 to 3 weeks. (Contraindication, High)
Top reaction signals
Loss of hearing (1) Deafness (1) Vomiting (1) Vocalisation (1) Unsteady walking (ataxia) (1) Tympanic alteration (1) Tiredness (lethargy) (1) Scratching (1)

Identifiers & Packages

Normalized identifiers (NDC/NADA/ANADA) and package metadata from regulator listings.

Identifiers
ANADA: 200565 NADA: 13022 NADA: 13407 NADA: 13954 NADA: 14350 NADA: 15123 NADA: 15875 NADA: 30103 NADA: 30578 NADA: 34114 NADA: 35631 NADA: 37410 NADA: 40205 NADA: 42633 NADA: 42910 NADA: 43141 NADA: 44654 NADA: 47333 NADA: 48487 NADA: 49461 NADA: 91067 NADA: 98689 NDC Package: 0010-5587-01 NDC Package: 0010-5587-02
Package NDC Product NDC Form / Route Status
0010-5587-01 0010 -
0010-5587-02 0010 -
0010-5587-03 0010 -
0010-5587-04 0010 -
66651-101-11 66651 -
66651-101-12 66651 -
66651-101-13 66651 -
66651-101-14 66651 -
66651-101-15 66651 -
66651-101-16 66651 -
66651-101-17 66651 -

Enriched Documents

Documents are tiered by source trust: Official, Clinical, Manufacturer, Marketing.

  • UCM452230.pdf • FOI summary • Official • May 3, 2023
    FDA FOI summary for application 15875
  • UCM457231.pdf • FOI summary • Official • June 1, 2016
    FDA FOI summary for application 200565

Data Sources & Change Log

Every non-trivial field is expected to include provenance and update timestamps.

Official 5 Clinical 0 Manufacturer 0 Marketing 0
Current Field Facts
  • contraindications: As a single oral dose. Milk taken from animals during treatment and within 96 hours (8 milkings) after the latest treatment must not be used for food. In sever… (Official, 2026-02-12)
  • side_effects: Top reported reactions (openFDA): Lethargy (see also Central nervous system depression in 'Neurological'), Loss of hearing, Deafness, Lack of efficacy - NOS, V… (Official, 2026-02-12)
  • usage: For control of infections of gastrointestinal roundworms in sheep and goats. (Trichostrongylus species, Haemonchus species, Ostertagia species, Cooperia specie… (Official, 2026-02-12)
Recent Revisions
  • side_effects updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields
  • usage updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields

FDA Products & Applications (Animal Drugs @ FDA)

Official sponsor/proprietary-name/application-status records linked by active ingredient.

Product Sponsor Application Status Published
E-Z-EX Wormer Mintrate Block
OTC
Thiabendazole
Medicated Feed Block • Oral
Label highlights
Official documents
ADM Animal Nutrition NADA 42910 W Feb 27, 2024
E-Z-EX Wormer Pellets
OTC
Thiabendazole
Pellet • Oral
Official documents
ADM Animal Nutrition NADA 30578 W Feb 27, 2024
Equizole®
OTC
Thiabendazole
Suspension • Oral
Label highlights
Official documents
Boehringer lngelheim Animal Health USA Inc. NADA 34114 W May 3, 2023
Equizole® 50% Wormer Paste For Horses Equizole® 50% Wormer Paste
OTC
Thiabendazole
Paste • Oral
Label highlights
Official documents
Boehringer lngelheim Animal Health USA Inc. NADA 98689 W May 3, 2023
Equizole® A
RX
Piperazine Phosphate Thiabendazole
Paste • Oral
Label highlights
Official documents
Boehringer lngelheim Animal Health USA Inc. NADA 37410 W May 3, 2023
Equizole® A Liquid
RX
Piperazine Citrate Thiabendazole
Liquid • Nasogastric, Oral
Label highlights
Official documents
Boehringer lngelheim Animal Health USA Inc. NADA 47333 W May 3, 2023
Equizole® Horse Wormer
RX
Thiabendazole
Top Dressing In Feed • Oral
Label highlights
Official documents
Boehringer lngelheim Animal Health USA Inc. NADA 13407 W May 3, 2023
Equizole® Horse Wormer Pellets
OTC
Thiabendazole
Top Dressing In Feed • Oral
Label highlights
Official documents
Boehringer lngelheim Animal Health USA Inc. NADA 44654 W May 3, 2023
Omnizole
OTC
Thiabendazole
Drench • Oral
Label highlights
Official documents
Boehringer lngelheim Animal Health USA Inc. NADA 14350 W May 3, 2023
TBZ 200 Medicated Feed Premix
OTC
Thiabendazole
Medicated Feed • Oral
Label highlights
Official documents
Boehringer lngelheim Animal Health USA Inc. NADA 15875 W May 3, 2023
TBZ® Cattle Wormer (Drench)
OTC
Thiabendazole
Liquid (Solution) • Oral
Label highlights
Official documents
Boehringer lngelheim Animal Health USA Inc. NADA 15123 W May 3, 2023
TBZ® Wormer Paste 43%
OTC
Thiabendazole
Paste • Oral
Label highlights
Official documents
Boehringer lngelheim Animal Health USA Inc. NADA 49461 W May 3, 2023
TBZ® Wormer Paste 50%
OTC
Thiabendazole
Paste • Oral
Label highlights
Official documents
Boehringer lngelheim Animal Health USA Inc. NADA 48487 W May 3, 2023
Thibenzole (18 mg)
OTC
Thiabendazole
Drench • Oral
Label highlights
Official documents
Boehringer lngelheim Animal Health USA Inc. NADA 30103 W May 3, 2023
Thibenzole 20% Swine Premix
OTC
Thiabendazole
Medicated Feed • Oral
Label highlights
Official documents
Boehringer lngelheim Animal Health USA Inc. NADA 13954 W May 3, 2023
Thibenzole 300 Medicated
OTC
Thiabendazole
Paste • Oral
Label highlights
Official documents
Boehringer lngelheim Animal Health USA Inc. NADA 43141 W May 3, 2023
Thibenzole Pig Wormer
OTC
Thiabendazole
Paste • Oral
Label highlights
Official documents
Boehringer lngelheim Animal Health USA Inc. NADA 35631 W May 3, 2023
Thibenzole Sheep & Goat Wormer
OTC
Thiabendazole
Liquid (Solution) • Oral
Label highlights
Official documents
Boehringer lngelheim Animal Health USA Inc. NADA 13022 W May 3, 2023
Purina® Horse Wormer Medicated
OTC
Thiabendazole
Top Dressing In Feed • Oral
Label highlights
Official documents
Virbac AH, Inc. NADA 40205 W Mar 15, 2019
Equizole®-B Equivet-14
RX
Thiabendazole Trichlorfon
Liquid • Oral, Nasogastric
Label highlights
Official documents
Farnam Companies, Inc. NADA 91067 Approved Jun 1, 2016
Thiabendazole, Dexamethasone, Neomycin Sulfate Solution
RX
Dexamethasone Neomycin Sulfate Thiabendazole
Solution • Topical
Label highlights
Official documents
Dechra Veterinary Products LLC ANADA 200-565 Approved Jun 1, 2016
Tresaderm Dermatologic Solution
RX
Dexamethasone Neomycin Sulfate Thiabendazole
Liquid (Solution) • Topical
Label highlights
Official documents
Boehringer lngelheim Animal Health USA, Inc. NADA 42633 Approved Jun 1, 2016

Data source: FDA Animal Drugs @ FDA (public search export).

What It's For (FDA Label Highlights)

Extracted from FDA Animal Drugs @ FDA product labeling. Always confirm details with your veterinarian.

Species: Pasture
Composition / specifications
Conforms to National Formulary XII.
Cattle
Indication
For control of infections of gastrointestinal roundworms (Trichostrongylus, Haemonchus Ostertagia, and Cooperia).
Dosage
3.3 percent feed block consumed at the recommended level of 0.11 pound per 100 pounds of body weight per day.
Limitations
Administer to cattle on pasture or range accustomed to mineral protein block feeding for 3 days. Milk taken from animals during treatment and within 96 hours (8 milkings) after the latest treatment must not be used for food. For a satisfactory diagnosis a microscopic fecal examination should be performed by a veterinarian or diagnostic laboratory prior to worming. Animals maintained under conditions of constant worm exposure may require re-treatment within 2 to 3 weeks. Animals that are severely parasitized, sick, or off feed should be isolated and a veterinarian consulted for advice concerning treatment.

FDA page: Open in Animal Drugs @ FDA

Species: Horse, Not For Meat Production • Goat, No Use Class Stated Or Implied • No Use Class Stated Or Implied • Sheep, No Use Class Stated Or Implied
Horses
Indication
For the control of infections of large strongyles (Strongylus vulgaris, Strongylus edentates), small strongyles (Cyathostomum, Cylicobrachytus and related genera, Craterostomum, Oesophagodontus, Poteriostomum), pinworms (Oxyuris), and threadworms (Strongyloides).
Dosage
2 grams per 100 pounds of body weight
Limitations
Not for use in horses to be slaughtered for food purposes. When administered by stomach tube, for use only by or on the order of a licensed veterinarian. When for use as a liquid oral drench or an oral paste, consult your veterinarian for assistance in the diagnosis, treatment, and control of parasitism.

FDA page: Open in Animal Drugs @ FDA

Species: Horse, Not For Meat Production
Composition / specifications
Conforms to National Formulary XII. As a single liquid oral dose, administered as an oral paste.
Horses
Indication
For the control of infections of large strongyles (Strongylus vulgaris, Strongylus edentates), small strongyles (Cyathastomum, Cylicobrachytus and related genera, Craterostomum, Oesophagodontus, Poteriostomum), pinworms (Oxyuris), and threadworms (Strongyloides).
Dosage
2 grams per 100 pounds of body weight.
Limitations
Not for use in horses to be slaughtered for food purposes. When administered by stomach tube, for use only by or on the order of a licensed veterinarian. When for use as a liquid oral drench or an oral paste, consult your veterinarian for assistance in the diagnosis, treatment, and control of parasitism.

FDA page: Open in Animal Drugs @ FDA

Species: Horse, Not For Meat Production
Composition / specifications
Each ounce of water dispersible powder contains 6.67 grams of thiabendazole and 8.33 grams of piperazine (as piperazine phosphate).
Horses
Indication
Treatment of infections of large strongyles (genus Strongylus), small strongyles (genera Cyathostomum, Cylicobrachytus, and related genera Craterostomum, Oesophagodontus, Poteriostomum), pinworms (Oxyuris), threadworms (Strongyloides), and ascarids (Parascaris) in horses.
Dosage
2 grams of thiabendazole and 2.5 grams of piperazine (0.3 ounce of powder) per 100 pounds of body weight.
Limitations
Use a single oral dose. Administer as a drench or by stomach tube suspended in 1 pint of warm water; by dose syringe suspended in ounce of water for each 100 pounds of body weight; or sprinkled over a small amount of daily feed. Not for animals intended for food use. If the label bears directions for administration by stomach tube or drench, it shall also bear the statement “Caution: Federal law restricts this drug to use by or on the order of a licensed veterinarian;” if not labeled for use by stomach tube or drench, the label shall bear the statement “Consult your veterinarian for assistance in the diagnosis, treatment, and control of parasitism.”

FDA page: Open in Animal Drugs @ FDA

Species: Horse, Not For Meat Production
Composition / specifications
Each fluid ounce of suspension contains 2 grams of thiabendazole and 2.5 grams of piperazine (from piperazine citrate).
Horses
Indication
For the control of large strongyles, small strongyles, pinworms, Strongyloides and ascarids (including members of the genera Strongylus species, Cyathostomum species, Cylicobrachytus species and related genera Craterostomum species, Oesophagodontus species, Poteriostomum species, Oxyuris species species, and Parascaris species).
Dosage

It is administered to horses by stomach tube or as a drench at the rate of 1 fluid ounce of suspension per 100 pounds of body weight.

Limitations

Do not use in horses intended to be used for food purposes. For use by or on the order of a licensed veterinarian.

FDA page: Open in Animal Drugs @ FDA

Species: Horse, Not For Meat Production
Composition / specifications
Conforms to National Formulary XII.
Horses
Indication
For control of large and small strongyles, Strongyloides, and pinworms of the genera Strongylus, Cyathostomum, Cylicobrachytus and related genera, Craterostomum, Oesophagodontus, Poteriostomum, Oxyuris, and Strongyloides.
Dosage
2 grams per 100 pounds of body weight in feed, as a top dressing
Limitations
Administer in a single dosage mixed with the normal grain ration given at one feeding. Warning: Not for use in horses intended for food.
Indication
For control of ascarids of the genus Parascaris.
Dosage
4 grams per 100 pounds of body weight in feed, as a top dressing.
Limitations
Administer in a single dosage mixed with the normal grain ration given at one feeding. Warning: Not for use in horses intended for food.

FDA page: Open in Animal Drugs @ FDA

Species: Horse, Not For Meat Production
Composition / specifications
Thiabendazole top dressing and mineral protein feed block.
Horses
Indication
For control of large strongyles, small strongyles, pinworms, and threadworms (including members of the genera Strongylus, Cyathostomum, Cylicobrachytus and related genera, Craterostomum, Oesophagodontus, Poteriostomum, Oxyuris, and Strongyloides).
Dosage
2 grams per 100 pounds of body weight in feed.
Limitations
Add to the usual feed of horses mixed into that amount of the feed normally consumed at one feeding. Warning: Not for use in horses intended for food.
Indication
For control of ascarids of the genus Parascaris.
Dosage
4 grams per 100 pounds of body weight in feed.
Limitations
Administer in a single dosage mixed with the normal grain ration given at one feeding. Warning: Not for use in horses intended for food.

FDA page: Open in Animal Drugs @ FDA

Species: Goat, No Use Class Stated Or Implied • No Use Class Stated Or Implied • Sheep, No Use Class Stated Or Implied
Composition / specifications
Conforms to National Formulary XII.
Cattle
Indication
Control of infections of Cooperia species or severe infections of other species
Dosage
5 grams administered orally as a drench using a dosing gun designed for the product per 100 pounds of body weight.
Limitations
For most effective results, severely parasitized animals or those constantly exposed to helminth infection should be re-treated every 2 to 3 weeks. Milk taken from treated animals within 96 hours (8 milkings) after the latest treatment must not be used for food. For a satisfactory diagnosis, a microscopic fecal examination should be performed prior to worming.
Indication
Control of infections of gastrointestinal roundworms (Trichostrongylus species Haemonchus species, Nematodirus species., Ostertagia species, and Oesophagostomum radiatum).
Dosage
3 grams administered orally as a drench using a dosing gun designed for the product per 100 pounds of body weight.
Limitations
For most effective results, severely parasitized animals or those constantly exposed to helminth infection should be re-treated every 2 to 3 weeks. Milk taken from treated animals within 96 hours (8 milkings) after the latest treatment must not be used for food. For a satisfactory diagnosis, a microscopic fecal examination should be performed prior to worming.
Sheep
Indication
Control of infections of gastrointestinal roundworms in sheep. (Trichostrongylus species, Haemonchus species, Ostertagia species, Cooperia species, Nematodirus species, Bunostomum species, Strongyloides species, Chabertia species and Oesophagostomum species); also active from 3 hours to 3 days following treatment against ova and larvae passed by sheep (good activity against Trichostrongylus colubriformis and axei, Ostertagia species, Bunostomum species, Nematodirus species, and Strongyloides species; less effective against Haemonchus contortus and Oesophagostomum species).
Dosage
2 grams, orally, as a drench, per 100 pounds of body weight.
Limitations
As a single oral dose. Milk taken from treated animals within 96 hours (8 milkings) after the latest treatment must not be used for food. In severe infections in sheep, treatment should be repeated in 2 to 3 weeks.
Goats
Indication
Control of infections of gastrointestinal roundworms in goats. (Trichostrongylus species, Haemonchus species, Ostertagia species, Cooperia species, Nematodirus species, Bunostomum species, Strongyloides species, Chabertia species and Oesophagostomum species); also active from 3 hours to 3 days following treatment against ova and larvae passed by sheep (good activity against Trichostrongylus colubriformis and axei, Ostertagia species, Bunostomum species, Nematodirus species, and Strongyloides species; less effective against Haemonchus contortus and Oesophagostomum species).
Dosage
2 grams, orally, as a drench, per 100 pounds of body weight.
Limitations
As a single oral dose. Milk taken from treated animals within 96 hours (8 milkings) after the latest treatment must not be used for food.
Indication
Control of severe infections of gastrointestinal roundworms (Trichostrongylus species, Haemonchus species, Ostertagia species, Cooperia species, Nematodirus species, Bunostomum species, Strongyloides species, Chabertia species, and Oesophagostomum species).
Dosage
3 grams, orally, as a drench, per 100 pounds of body weight.
Limitations
As a single oral dose. Milk taken from treated animals within 96 hours (8 milkings) after the latest treatment must not be used for food. Treatment should be repeated in 2 to 3 weeks.

FDA page: Open in Animal Drugs @ FDA

Species: Goat, No Use Class Stated Or Implied • No use class stated or implied • No Use Class Stated Or Implied • Pheasant, No Use Class Stated Or Implied • Sheep, No Use Class Stated Or Implied
Composition / specifications
22, 44.1 66.1, or 88.2 percent
Sheep
Indication

Control of infections of gastrointestinal roundworms (Trichostrongylus species, Haemonchus species, Ostertagia species, Cooperia species; Nematodirus species, ,i>Bunostomum species, Strongyloides species, Chabertia species, and Oesophagostomum species); also active against ova and larvae passed by sheep from 3 hours to 3 days after the feed is consumed (good activity against ova and larvae of T. colubriformis and T.axei, Ostertagia species, Nematodirus species, Strongyloides species; less effective against those of Haemonchus contortus and Oesophagostomum species).

Dosage
2 grams in feed per 100 pounds body weight.
Limitations
Do not use in Type B or Type C medicated feed containing bentonite.
Cattle
Indication

Control of severe infections of gastrointestinal roundworms (Trichostrongylus species, Haemonchus species, Ostertagia species, Nematodirus species, Oesophagostomum radiatum); control of infections of Cooperia species.

Dosage
5 grams in feed per 100 pounds body weight.
Limitations
Do not use in Type B or Type C medicated feed containing bentonite.
Indication

Control of infections of gastrointestinal roundworms (Trichostrongylus species, Haemonchus species, Ostertagia species, Nematodirus species, Oesophagostomum radiatum).

Dosage
3 grams in feed per 100 pounds body weight.
Limitations
Do not use in Type B or Type C medicated feed containing bentonite.
Pheasants
Indication
For the treatment of gapeworms (Syngamus trachea) in pheasants.
Dosage
454 grams per ton of feed (0.05 percent) continuously for 2 weeks (14 days).
Limitations
Fertility, hatchability, and other reproductive data are not available on use in breeding animals. Do not use in Type B or Type C medicated feed containing bentonite.
Swine
Indication
Aid in the prevention of infections of large roundworms (genus Ascaris).
Dosage
45.4- 908 grams per ton of feed (0.005-0.1 percent).
Limitations
Do not use in Type B or Type C medicated feed containing bentonite.
Goats
Indication

Control of infections of gastrointestinal roundworms (Trichostrongylus species, Haemonchus species, Ostertagia species, Cooperia species; Nematodirus species, Bunostomum species, Strongyloides species, Chabertia species, and Oesophagostomum species); also active against ova and larvae passed by sheep from 3 hours to 3 days after the feed is consumed (good activity against ova and larvae of T. colubriformis and T. axei, Ostertagia species, Nematodirus species, Strongyloides species; less effective against those of Haemonchus contortus and Oesophagostomum species).

Dosage
2 grams in feed per 100 pounds body weight.
Limitations
Use 2 grams per 100 pounds body weight at a single dose. Do not use in Type B or Type C medicated feed containing bentonite.
Indication

Control of severe infections of gastrointestinal roundworms (Trichostrongylus species, Haemonchus species, Ostertagia species, Cooperia species, Nematodirus species, Bunostomum species, Strongyloides species, Chabertia species, and Oesophagostomum species).

Dosage
3 grams in feed per 100 pounds body weight.
Limitations
Do not use in Type B or Type C medicated feed containing bentonite.

FDA page: Open in Animal Drugs @ FDA

Species: No Use Class Stated Or Implied
Composition / specifications
Conforms to National Formulary XII.
Cattle
Indication
Control of infections of gastrointestinal roundworms (Trichostrongylus species, Haemonchus species, Nematodirus species, Ostertagia species, and Oesophagostomum radiatum).
Dosage
3 grams orally as a drench per 100 pounds of body weight
Limitations
For most effective results, severely parasitized animals or those constantly exposure to helminth infection should be re-treated every 2 to 3 weeks. Milk taken from treated animals within 96 hours (8 milkings) after the latest treatment must not be used for food. Do not treat cattle within 3 days of slaughter. For a satisfactory diagnosis, a microscopic fecal examination should be performed by a veterinarian or diagnostic laboratory prior to worming.
Indication
Control of infections of Cooperia species or severe infections of gastrointestinal roundworms (Trichostrongylus species, Haemonchus species, Nematodirus species, Ostertagia species, and Oesophagostomum radiatum).
Dosage
5 grams orally as a drench per 100 pounds of body
Limitations
For most effective results, severely parasitized animals or those constantly exposure to helminth infection should be re-treated every 2 to 3 weeks. Milk taken from animals during treatment and within 96 hours (8 milkings) after the latest treatment must not be used for food. Do not treat cattle within 3 days of slaughter. For a satisfactory diagnosis a microscopic fecal examination should be performed by a veterinarian or diagnostic laboratory prior to worming.

FDA page: Open in Animal Drugs @ FDA

Species: No Use Class Stated Or Implied
Cattle
Indication
Control of infections of Cooperia species or severe infections of gastrointestinal roundworms (Trichostrongylus species, Haemonchus species, Nematodirus species, Ostertagia species, and Oesophagostomum radiatum).
Dosage
5 grams per 100 pounds of body weight orally as a drench and in paste form using a dosing gun designed for the product.
Limitations
For most effective results, severely parasitized animals or those constantly exposed to helminth should be re-treated every 2 to 3 weeks. Milk taken from treated animals within 96 hours (8 milkings) after the latest treatment must not be used for food. Do not treat cattle within 3 days of slaughter. For a satisfactory diagnosis, a microscopic fecal examination should be performed prior to worming.
Indication
Control of infections of gastrointestinal roundworms (Trichostrongylus species, Haemonchus species, Nematodirus species, Ostertagia species, and Oesophagostomum radiatum).
Dosage
3 grams per 100 pounds of body weight orally as a drench and in paste form using a dosing gun designed for the product.
Limitations
For most effective results, severely parasitized animals or those constantly exposed to helminth infection should be re-treated every 2 to 3 weeks. Milk taken from treated animals within 96 hours (8 milkings) after the latest treatment must not be used for food. Do not treat cattle within 3 days of slaughter. For a satisfactory diagnosis, a microscopic fecal examination should be performed prior to worming.

FDA page: Open in Animal Drugs @ FDA

Species: No Use Class Stated Or Implied
Cattle
Indication
Control of infections of Cooperia species or severe infections of gastrointestinal roundworms (Trichostrongylus species, Haemonchus species, Nematodirus species, Ostertagia species, and Oesophagostomum radiatum).
Dosage
5 grams per 100 pounds of body weight orally as a drench and in paste form using a dosing gun designed for the product.
Limitations
For most effective results, severely parasitized animals or those constantly exposed to helminth should be re-treated every 2 to 3 weeks. Milk taken from treated animals within 96 hours (8 milkings) after the latest treatment must not be used for food. For a satisfactory diagnosis a microscopic fecal examination should be performed prior to worming.
Indication
Control of infections of gastrointestinal roundworms (Trichostrongylus species, Haemonchus species, Nematodirus species, Ostertagia species, and Oesophagostomum radiatum).
Dosage
3 grams per 100 pounds of body weight orally as a drench and in paste form using a dosing gun designed for the product.
Limitations
For most effective results, severely parasitized animals or those constantly exposed to helminth infection should be re-treated every 2 to 3 weeks. Milk taken from treated animals within 96 hours (8 milkings) after the latest treatment must not be used for food. For a satisfactory diagnosis, a microscopic fecal examination should be performed prior to worming.

FDA page: Open in Animal Drugs @ FDA

Species: No Use Class Stated Or Implied
Composition / specifications
Conforms to National Formulary XII.
Cattle
Indication
Control of infections of Cooperia species or severe infections of other species
Dosage
5 grams per 100 pounds of body weight administered orally as a drench using a dosing gun designed for the product.
Limitations
For most effective results, severely parasitized animals or those constantly exposed to helminth should be re-treated every 2 to 3 weeks. Milk taken from treated animals within 96 hours (8 milkings) after the latest treatment must not be used for food. Do not treat cattle within 3 days of slaughter. For a satisfactory diagnosis a microscopic fecal examination should be performed prior to worming.
Indication
Control of infections of gastrointestinal roundworms (Trichostrongylus species Haemonchus species, Nematodirus species, Ostertagia species, and Oesophagostomum radiatum).
Dosage
3 grams per 100 pounds of body weight administered orally as a drench using a dosing gun designed for the product.
Limitations
For most effective results, severely parasitized animals or those constantly exposed to helminth infection should be re-treated every 2 to 3 weeks. Milk taken from treated animals within 96 hours (8 milkings) after the latest treatment must not be used for food. For a satisfactory diagnosis, a microscopic fecal examination should be performed prior to worming.

FDA page: Open in Animal Drugs @ FDA

Species: No use class stated or implied
Composition / specifications
Dry Type A medicated articles: 22, 44.1, or 66.1 percent.
Swine
Indication
Aid in the prevention of infections of large roundworms (genus Ascaris
Dosage
45.4-908 grams per ton of feed (0.005- 0.1 percent).
Limitations
Administer continuously feed containing 0.05-0.1 percent thiabendazole per ton for 2 weeks followed by feed containing 0.005-0.02 percent thiabendazole per ton for 8-14 weeks. Do not treat animals within 30 days of slaughter. Do not use in Type B or Type C medicated feed containing bentonite.

FDA page: Open in Animal Drugs @ FDA

Species: No Use Class Stated Or Implied
Composition / specifications
Conforms to National Formulary.
Cattle
Indication
Control of infections of Cooperia species or severe infections of other species.
Dosage
5 grams per 100 pounds of body weight orally as a drench and in paste form using a dosing gun designed for the product.
Limitations
For most effective results, severely parasitized animals or those constantly exposed to helminth should be re-treated every 2 to 3 weeks. Milk taken from treated animals within 96 hours (8 milkings) after the latest treatment must not be used for food. For a satisfactory diagnosis, a microscopic fecal examination should be performed prior to worming.
Indication
Control of infections of gastrointestinal roundworms (Trichostrongylus species Haemonchus species, Nematodirus species, Ostertagia species, and Oesophagostomum radiatum).
Dosage
3 grams per 100 pounds of body weight orally as a drench and in paste form using a dosing gun designed for the product.
Limitations
For most effective results, severely parasitized animals or those constantly exposed to helminth infection should be re-treated every 2 to 3 weeks. Milk taken from treated animals within 96 hours (8 milkings) after the latest treatment must not be used for food. For a satisfactory diagnosis, a microscopic fecal examination should be performed prior to worming.

FDA page: Open in Animal Drugs @ FDA

Species: 1 to 8 weeks of age
Composition / specifications
Conforms to National Formulary XII.
Swine (baby pigs)
Indication
For control of infections with Strongyloides ransomi. These infections are commonly found in Southeastern United States.
Dosage
200 milligrams for each 5 to 7 pounds of body weight per dose as an oral paste.
Limitations
Administer to baby pigs (1 to 8 weeks of age). Treatment may be repeated in 5 to 7 days if necessary. Before treatment, obtain an accurate diagnosis from a veterinarian or diagnostic laboratory. Do not treat within 30 days of slaughter.

FDA page: Open in Animal Drugs @ FDA

Species: Goat, No Use Class Stated Or Implied • Sheep, No Use Class Stated Or Implied
Composition / specifications
Conforms to National Formulary XII.
Sheep
Indication
For control of infections of gastrointestinal roundworms in sheep and goats. (Trichostrongylus species, Haemonchus species, Ostertagia species, Cooperia species, Nematodirus species, Bunostomom species, Strongyloides species, Chabertia species, and Oesophagostomum species); also active from 3 hours to 3 days following treatment against ova and larvae passed by sheep (good activity against Trichostrongylus colubriformis and axei, Ostertagia species, Bunostomom species, Nematodirus species, Strongyloides species; less effective against Haemonchus contortus and Oesophagostomum species).
Dosage
2 grams per 100 pounds of body weight orally, as a drench
Limitations
As a single oral dose. Milk taken from animals during treatment and within 96 hours (8 milkings) after the latest treatment must not be used for food. In severe infections in sheep, treatment should be repeated in 2 to 3 weeks.
Goats
Indication
For control of infections of gastrointestinal roundworms in sheep and goats. (Trichostrongylus species, Haemonchus species, Ostertagia species, Cooperia species, Nematodirus species, Bunostomom species, Strongyloides species, Chabertia species, and Oesophagostomum species); also active from 3 hours to 3 days following treatment against ova and larvae passed by sheep (good activity against Trichostrongylus colubriformis and axei, Ostertagia species, Bunostomom species, Nematodirus species, Strongyloides species; less effective against Haemonchus contortus and Oesophagostomum species).
Dosage
2 grams per 100 pounds of body weight orally, as a drench
Limitations
As a single oral dose. Milk taken from animals during treatment and within 96 hours (8 milkings) after the latest treatment must not be used for food.
Indication
Control of severe infections of gastrointestinal roundworms (Trichostrongylus species, Haemonchus species, Ostertagia species, Cooperia species, Nematodirus species, Bunostomom species, Strongyloides species, Chabertia species, and Oesophagostomum species).
Dosage
3 grams per 100 pounds of body weight orally, as a drench
Limitations
As a single oral dose. Milk taken from treated animals within 96 hours (8 milkings) after the latest treatment must not be used for food. Treatment should be repeated in 2 to 3 weeks.

FDA page: Open in Animal Drugs @ FDA

Species: Horse, Not For Meat Production
Composition / specifications
Conforms to National Formulary XII.
Horses
Indication

For control of large and small strongyles, Strongyloides, and pinworms of the genera Strongylus, Cyathostomum, Cylicobrachytus and related genera, Craterostomum, Oesophagodontus, Poteriostomum, Oxyuris, and Strongyloides.

Dosage
2 grams per 100 pounds in feed.
Limitations
Administer in a single dosage mixed with the normal grain ration given at one feeding. Warning: Not for use in horses intended for food.

FDA page: Open in Animal Drugs @ FDA

Species: Horse, Restricted During Pregnancy • Horse, Foals, 4 Months And Older • Horse, Not For Meat Production
Composition / specifications
The drug contains 5 grams of thiabendazole with 4.5 grams of trichlorfon, or 20 grams of thiabendazole with 18 grams of trichlorfon.
Horses
Indication
Used for the treatment and control of bots (Gasterophilus species), large strongyles (Strongylus species), small strongyles (genera Cyathostomum, Cylicobrachytus, Craterostomum, Oesophagodontus, Poteriostomum), pinworms (Oxyuris species, Strongyloides species), and ascarids (Parascaris species) in horses.
Dosage
Administer 2 grams of thiabendazole with 1.8 grams of trichlorfon per 100 pounds of body weight sprinkled on the animals' usual daily ration of feed, or may be mixed in 5 to 10 fluid ounces of water and administered by stomach tube or drench.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian.

FDA page: Open in Animal Drugs @ FDA

Species: Dog, No Use Class Stated Or Implied • Cat, No Use Class Stated Or Implied
Composition / specifications
Each milliliter of solution contains 40 milligrams (mg) thiabendazole, 3.2 mg neomycin (from neomycin sulfate), and 1 mg dexamethasone.
Label highlights
Indication
As an aid in the treatment of bacterial, mycotic, and inflammatory dermatoses and otitis externa
Dosage
In treating dermatoses affecting areas other than the ear, the surface of the lesions should be well moistened (2 to 4 drops per square inch) twice daily. In treating otitis externa, instill 5 to 15 drops in the ear twice daily. Treat for up to 7 days
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian

FDA page: Open in Animal Drugs @ FDA

Species: Dog, No Use Class Stated Or Implied • Cat, No Use Class Stated Or Implied
Composition / specifications
Each cubic centimeter of neomycin sulfate-thiabendazole-dexamethasone solution contains: 40 milligrams of thiabendazole, 3.2 milligrams of neomycin (from neomycin sulfate), and 1 milligram of dexamethasone.
Cats
Indication
The drug is recommended for use as an aid in the treatment of bacterial, mycotic, and inflammatory dermatoses and otitis externa in cats.
Dosage
In treating dermatoses affecting areas other than the ear, the surface of the lesions should be well moistened (two to four drops per square inch) twice daily. In treating otitis externa, five to 15 drops of the drug should be instilled in the ear twice daily. The is limited to 7 days maximum duration of administration.
Limitations
For use only by or on order of a licensed veterinarian.
Dogs
Indication
The drug is recommended for use as an aid in the treatment of bacterial, mycotic, and inflammatory dermatoses and otitis externa in dogs.
Dosage
In treating dermatoses affecting areas other than the ear, the surface of the lesions should be well moistened (two to four drops per square inch) twice daily. In treating otitis externa, five to 15 drops of the drug should be instilled in the ear twice daily. The is limited to 7 days maximum duration of administration.
Limitations
For use only by or on order of a licensed veterinarian.

FDA page: Open in Animal Drugs @ FDA

Official Documents (FDA)

Direct links to FDA-hosted PDFs and SPL packages (when available).

SPL Packages

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SPL Packages

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SPL Packages

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SPL Packages

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SPL Packages

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Documents
  • Summary
    This supplement provides for the addition of the indication for treatment of gapeworms ( Syngamus trachea) in pheasants.
SPL Packages

FDA page: Open in Animal Drugs @ FDA

SPL Packages

FDA page: Open in Animal Drugs @ FDA

SPL Packages

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SPL Packages

FDA page: Open in Animal Drugs @ FDA

SPL Packages

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SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    As an aid in the treatment of certain bacterial, mycotic, and inflammatory dermatoses and otitis externa in dogs and cats.
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Usage

For control of infections of gastrointestinal roundworms in sheep and goats. (Trichostrongylus species, Haemonchus species, Ostertagia species, Cooperia species, Nematodirus species, Bunostomom species, Strongyloides species, Chabertia species, and Oesophagostomum species); also active from 3 hours to 3 days following treatment against ova and larvae passed by sheep (good activity against Trichostrongylus colubriformis and axei, Ostertagia species, Bunostomom species, Nematodirus species, Strongyloides species; less effective against Haemonchus contortus and Oesophagostomum species). Control of severe infections of gastrointestinal roundworms (Trichostrongylus species, Haemonchus species, Ostertagia species, Cooperia species, Nematodirus species, Bunostomom species, Strongyloides species, Chabertia species, and Oesophagostomum species). For control of large and small strongyles, Strongyloides, and pinworms of the genera Strongylus, Cyathostomum, Cylicobrachytus and related genera, Craterostomum, Oesophagodontus, Poteriostomum, Oxyuris, and Strongyloides.

Source: FDA Animal Drugs @ FDA • Reference

Contraindications

As a single oral dose. Milk taken from animals during treatment and within 96 hours (8 milkings) after the latest treatment must not be used for food. In severe infections in sheep, treatment should be repeated in 2 to 3 weeks. As a single oral dose. Milk taken from animals during treatment and within 96 hours (8 milkings) after the latest treatment must not be used for food. As a single oral dose. Milk taken from treated animals within 96 hours (8 milkings) after the latest treatment must not be used for food. Treatment should be repeated in 2 to 3 weeks.

Top Reported Reactions (openFDA)

De-duplicated reaction terms grouped by body system from FDA openFDA reports (not verified; does not prove causation).

Digestive
Vomiting (1) • Cat Loss of appetite (1) • Cat Decreased appetite (1) • Cat

Showing top 5 for Digestive.

Neurologic
Unsteady walking (1) • Cat Tiredness (1) • Cat

Showing top 5 for Neurologic.

Effectiveness
Lack of efficacy - NOS (1) • Dog Lack of efficacy (fungi) - NOS (1) • Dog

Showing top 5 for Effectiveness.

Other
Vocalisation (1) • Dog Tympanic alteration (1) • Cat Scratching (1) • Dog Reluctant to move (1) • Cat Pustules (1) • Dog
Show more (14)
Pinnal ulcer (1) • Dog Otitis media (1) • Cat Other abnormal test result NOS (1) • Dog Nystagmus (1) • Cat Not eating (1) • Cat Loss of hearing (1) • Cat Leucocytosis NOS (1) • Dog Increased drinking (1) • Cat Ear discharge (1) • Dog Decreased blood urea nitrogen (BUN) or creatinine (1) • Dog Deafness (1) • Dog Anaemia NOS (1) • Dog Abnormal radiograph finding (1) • Cat Abnormal cytology (1) • Cat

Showing top 5 for Other.

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Adverse Event Case Summaries (openFDA)

These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.

Cat, Domestic Shorthair, Male, 3 year, 5.65 kilogram • Drug: MSK, Topical, Dose: 6 drops per animal, Frequency: 12 per hour • Reactions: Tiredness (lethargy), Vomiting, Otitis media, Tympanic alteration, Abnormal radiograph finding… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-056132
  • Serious AE: No
  • Treated For AE: Yes
  • Sex: Male
  • Age: 3.00 Year
  • Weight: 5.650 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Topical
  • Dose: 6 drops per animal
  • Frequency: 12 per hour
Reactions Reported:
Tiredness (lethargy) Vomiting Otitis media Tympanic alteration Abnormal radiograph finding Not eating Abnormal cytology
Outcomes: Ongoing

Cat, Cat (unknown), Unknown • Drug: MSK, Unknown • Reactions: Increased drinking, Reluctant to move, Tiredness (lethargy) • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2025-US-054681
  • Serious AE: No
  • Treated For AE: No
  • Sex: Unknown
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Increased drinking Reluctant to move Tiredness (lethargy)
Outcomes: Recovered/Normal

Cat, American Shorthair, Female, 6 year, 4.781 kilogram • Drug: MSK, Auricular (Otic), Dose: 6 drops per animal, Frequency: 12 per hour • Reactions: Unsteady walking (ataxia), Loss of appetite, Nystagmus • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-054206
  • Serious AE: No
  • Treated For AE: Yes
  • Sex: Female
  • Age: 6.00 Year
  • Weight: 4.781 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Auricular (Otic)
  • Dose: 6 drops per animal
  • Frequency: 12 per hour
Reactions Reported:
Unsteady walking (ataxia) Loss of appetite Nystagmus
Outcomes: Outcome Unknown

Cat, Domestic Shorthair, Male, 8 year, 6.713 kilogram • Drug: MSK, Auricular (Otic) • Reactions: Tiredness (lethargy), Decreased appetite • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-055591
  • Serious AE: No
  • Treated For AE: No
  • Sex: Male
  • Age: 8.00 Year
  • Weight: 6.713 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Auricular (Otic)
Reactions Reported:
Tiredness (lethargy) Decreased appetite
Outcomes: Ongoing

Cat, British cat, Female, 18 month, 3.311 kilogram • Drug: MSK, Auricular (Otic), Dose: 5 drops per animal • Reactions: Loss of hearing • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-052431
  • Serious AE: Yes
  • Treated For AE: No
  • Sex: Female
  • Age: 18.00 Month
  • Weight: 3.311 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Auricular (Otic)
  • Dose: 5 drops per animal
Reactions Reported:
Loss of hearing
Outcomes: Outcome Unknown

Dog, Rottweiler, Female, 3 year, 42.41 kilogram • Drug: MSK • Reactions: Ear discharge • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2025-US-046347
  • Serious AE: No
  • Treated For AE: No
  • Sex: Female
  • Age: 3.00 Year
  • Weight: 42.410 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
Reactions Reported:
Ear discharge
Outcomes: Recovered/Normal

Dog, Chihuahua, Male, 3 month, 2.041 kilogram • Drug: MSK, Topical, Dose: 4 drops per animal, Frequency: 12 per hour • Reactions: Scratching, Vocalisation, Pinnal ulcer • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-037451
  • Serious AE: No
  • Treated For AE: Yes
  • Sex: Male
  • Age: 3.00 Month
  • Weight: 2.041 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Topical
  • Dose: 4 drops per animal
  • Frequency: 12 per hour
Reactions Reported:
Scratching Vocalisation Pinnal ulcer
Outcomes: Ongoing

Dog, Retriever - Golden, Male, 8 week, 7.257 kilogram • Drug: MSK, Unknown • Reactions: Leucocytosis NOS, Anaemia NOS, Decreased blood urea nitrogen (BUN) or creatinine, Other abnormal test result NOS, Ear discharge… • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-036873
  • Serious AE: No
  • Treated For AE: Yes
  • Sex: Male
  • Age: 8.00 Week
  • Weight: 7.257 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Leucocytosis NOS Anaemia NOS Decreased blood urea nitrogen (BUN) or creatinine Other abnormal test result NOS Ear discharge Pustules
Outcomes: Outcome Unknown

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Overdose Information

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Storage & Handling

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