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Famotidine

Detailed information about Famotidine

Official label facts Owner quick guide first Marketing clearly labeled
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Reviewed / Updated / Sources

Reviewed: Not available

Updated: February 12, 2026, 7:40 PM UTC

Sources:

Pet Owner Quick Guide

Start here first for the simple next-step summary.

Used for:

Acid-reducing medication used for GI upset and reflux.

What to watch for:

  • Dose adjustments may be needed in kidney disease
  • wobbly/unsteady walking (1 reports)
  • trouble breathing (1 reports)
  • Loss of appetite (1 reports)

When to call the vet:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Facial swelling or hives.
  • Blood in vomit or stool.

What to ask your vet today:

  • Is this medicine the right fit for my pet’s current symptoms?
  • Which warning signs mean I should call back right away?
  • How should I handle missed doses or refusal to take the medicine?
Safety & side effects

What to watch:

  • Dose adjustments may be needed in kidney disease
  • wobbly/unsteady walking
  • trouble breathing
  • Loss of appetite

Most reported reactions:

  • Unsteady walking (ataxia) (1 reports)
  • Trouble breathing (dyspnea) (1 reports)
  • Loss of appetite (1 reports)

When to call your vet:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Facial swelling or hives.
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Data freshness: source data appears current.

Latest refresh: Mar 21, 2026, 10:02 a.m.

Data freshness
  • Medication catalog: Source Roxee | Refreshed Feb 12, 2026, 7:40 PM UTC
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed Mar 21, 2026, 10:01 AM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
  • openFDA reaction terms: Source FDA openFDA | Refreshed Mar 21, 2026, 10:02 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Feb 9, 2026, 3:19 AM UTC
Image coming soon
Famotidine

Famotidine

Drug type: Generic ingredient • Generic profile • No FDA branded products linked

Species: Both

Manufacturer: Not available (source)

Quick Facts

Official label facts first, then secondary summaries. Marketing content is separated below.

Species: Both
Manufacturer: Not available

Warnings / Contraindications

Dose adjustments may be needed in kidney disease.

  • High: Dose adjustments may be needed in kidney disease.
Source metadata:

Adverse Reactions

Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.

Tap or hover a reaction to see what it means in plain language.

Tracked signals
32
Reported cases
32
Serious reports
22
Species represented
2
Grouped by Body System
Digestive (4) · Loss of appetite, Drooling, Diarrhea Neurologic (1) · Unsteady walking (ataxia) Behavior (1) · Behavioral disorder (unspecified) Effectiveness (1) · Lack of efficacy (ectoparasite) - flea Other (25) · Trouble breathing (dyspnea), Increased respiratory rate, Hypotension
Most Reported Reactions
Reaction Body system Cases Species Serious cases
Neurologic 1 Dog 1
Other 1 Dog 1
Digestive 1 Dog 1
Other 1 Dog 1
Other 1 Dog 1
Other 1 Dog 1
Other 1 Dog 1
Other 1 Cat 1

Species coverage: Dog (22) Cat (10)

View detailed reaction table
Reaction Body system Species Seriousness Frequency Reports
Neurologic Dog Serious - 1
Other Dog Serious - 1
Digestive Dog Serious - 1
Effectiveness Cat Non-serious - 1
Other Cat Non-serious - 1
Other Cat Non-serious - 1
Other Cat Non-serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Cat Non-serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Other Dog Non-serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Other Dog Serious - 1
Other Cat Non-serious - 1
Digestive Dog Serious - 1
Digestive Dog Serious - 1
Other Dog Non-serious - 1
Digestive Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Cat Non-serious - 1
Behavior Dog Serious - 1
Other Dog Non-serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Source metadata:

Storage & Handling

Store at room temperature.

Veterinary reference (advanced)

Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.

At a Glance

Quick facts and links to official labeling and safety signals.

Data freshness
  • Medication catalog: Source Roxee | Refreshed Feb 12, 2026, 7:40 PM UTC
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed Mar 21, 2026, 10:01 AM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
  • openFDA reaction terms: Source FDA openFDA | Refreshed Mar 21, 2026, 10:02 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Feb 9, 2026, 3:19 AM UTC
Official (FDA)
Identity: Generic ingredient • No FDA branded products linked
No official FDA brand rows linked yet for this ingredient.
Case-reported brands (openFDA): MSK
Catalog species: Both
Safety (openFDA)
Top reactions: Dog 27 • Cat 24 • View
Case summaries: 10 (showing 8) • View
openFDA reports are unverified and do not prove causation.
Diagnosis Codes

Diagnosis-code mappings are not available for this medication yet.

Counseling and Monitoring Highlights

Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.

Owner-facing counseling points
  • Dose adjustments may be needed in kidney disease. (Contraindication, High)
Top reaction signals
Unsteady walking (ataxia) (1) Trouble breathing (dyspnea) (1) Loss of appetite (1) Hyperthermia (1) Hyperphosphataemia (1) Hind limb paresis (1) General pain (1) Gastroenteritis (1)

Data Sources & Change Log

Every non-trivial field is expected to include provenance and update timestamps.

Official 1 Clinical 3 Manufacturer 0 Marketing 0
Current Field Facts
  • contraindications: Dose adjustments may be needed in kidney disease. (Clinical, 2026-02-12)
  • storage_handling: Store at room temperature. (Clinical, 2026-02-12)
  • usage: Acid-reducing medication used for GI upset and reflux. (Clinical, 2026-02-12)
  • side_effects: Generally well tolerated; occasional GI upset. (Official, 2026-02-12)
Recent Revisions
  • side_effects updated 2026-02-12 19:40 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-02-12 19:40 by etl_backfill • Backfilled from existing medication fields
  • usage updated 2026-02-12 19:40 by etl_backfill • Backfilled from existing medication fields

Usage

Acid-reducing medication used for GI upset and reflux.

Contraindications

Dose adjustments may be needed in kidney disease.

Side Effects

Generally well tolerated; occasional GI upset.

Source: FDA openFDA • Reference

Top Reported Reactions (openFDA)

De-duplicated reaction terms grouped by body system from FDA openFDA reports (not verified; does not prove causation).

Digestive
Loss of appetite (1) • Dog Drooling (1) • Dog Diarrhea (1) • Dog Decreased appetite (1) • Dog

Showing top 5 for Digestive.

Neurologic
Unsteady walking (1) • Dog

Showing top 5 for Neurologic.

Behavior
Behavioral disorder (1) • Dog

Showing top 5 for Behavior.

Effectiveness
Lack of efficacy (ectoparasite) - flea (1) • Cat

Showing top 5 for Effectiveness.

Other
Trouble breathing (1) • Dog Increased respiratory rate (1) • Cat Hypotension (1) • Cat Hypochloraemia (1) • Cat Hyperthermia (1) • Dog
Show more (20)
Hyperphosphataemia (1) • Dog Hyperglycaemia (1) • Cat Hind limb paresis (1) • Dog General pain (1) • Dog Gastroenteritis (1) • Cat Gait abnormality (1) • Dog Fever (1) • Dog Elevated serum alkaline phosphatase (1) • Dog Elevated globulins (1) • Cat Elevated creatinine (1) • Dog Elevated blood urea nitrogen (1) • Cat Depressed reflexes (1) • Dog Corneal ulcer (1) • Dog Cognitive disorder NOS (1) • Dog Bradycardia (1) • Cat Balance impaired (1) • Dog Bacterial skin infection NOS (1) • Dog Arthritis (1) • Dog Acid-base disorder (1) • Dog Abnormal radiograph finding (1) • Cat

Showing top 5 for Other.

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Adverse Event Case Summaries (openFDA)

These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.

Dog, Chihuahua, Female, 16 year, 3.12 kilogram • Drug: MSK, Unknown • Reactions: Reduced responses, Elevated creatinine, Corneal ulcer, Sleepiness - systemic disorder, Elevated blood urea nitrogen… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-055817
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 16.00 Year
  • Weight: 3.120 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Reduced responses Elevated creatinine Corneal ulcer Sleepiness - systemic disorder Elevated blood urea nitrogen Lack of efficacy - NOS Hyperphosphataemia
Outcomes: Ongoing

Cat, Cat (other), Male, 13 year, 3.49 kilogram • Drug: MSK, Unknown • Reactions: Slow heart rate, Recovery prolonged • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2025-US-055510
  • Serious AE: No
  • Treated For AE: Yes
  • Sex: Male
  • Age: 13.00 Year
  • Weight: 3.490 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Slow heart rate Recovery prolonged
Outcomes: Recovered/Normal

Dog, Terrier - Bull - American Pit, Male, 14 year, 24.494 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Stiff gait, Cognitive disorder NOS, Malaise, Vomiting, Diarrhea… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-055236
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 14.00 Year
  • Weight: 24.494 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Unassigned
Reactions Reported:
Stiff gait Cognitive disorder NOS Malaise Vomiting Diarrhea Hind limb paresis Unable to stand Unable to walk Proprioception deficit Tremors Fever Unsteady walking (ataxia) Behavioral disorder (unspecified)
Outcomes: Ongoing

Dog, Dog (unknown), Male, 10 year, 32.659 kilogram • Drug: MSK, Unknown • Reactions: Mass NOS, Lymph node abscess, Lymphadenopathy, Tachycardia, Drooling… • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-055759
  • Serious AE: Yes
  • Treated For AE: No
  • Sex: Male
  • Age: 10.00 Year
  • Weight: 32.659 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Mass NOS Lymph node abscess Lymphadenopathy Tachycardia Drooling Elevated serum alkaline phosphatase Monocytosis Neutrophilia Leucocytosis NOS Acid-base disorder Musculoskeletal disorder NOS Luxation/subluxation Arthritis Muscle tremor Tachypnoea Trouble breathing (dyspnea) Bacterial skin infection NOS Trauma NOS Hyperthermia Loss of appetite Oedema NOS Tiredness (lethargy) General pain
Outcomes: Outcome Unknown

Dog, Shepherd Dog - Australian, Male, 13 year • Drug: MSK, Tablet, Oral, Dose: 20 Milligram per animal, Frequency: 12 per hour • Reactions: Gait abnormality, Balance impaired, Whining, Lameness, Proprioception deficit… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-054764
  • Serious AE: No
  • Treated For AE: Yes
  • Sex: Male
  • Age: 13.00 Year
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet
  • Dose: 20 Milligram per animal
  • Frequency: 12 per hour
Reactions Reported:
Gait abnormality Balance impaired Whining Lameness Proprioception deficit Depressed reflexes Loss of strength
Outcomes: Ongoing

Dog, ['Hound - Basset', 'Dog (unknown)'], Female, 8.9 year, 16.33 kilogram • Drug: MSK, Tablet, Oral, Dose: 10 Milligram per animal, Frequency: 12 per hour • Reactions: Diarrhea, Vomiting, Decreased appetite, Low thyroxine • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-055287
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 8.90 Year
  • Weight: 16.330 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet
  • Dose: 10 Milligram per animal
  • Frequency: 12 per hour
Reactions Reported:
Diarrhea Vomiting Decreased appetite Low thyroxine
Outcomes: Outcome Unknown

Cat, Domestic Shorthair, Female, 15 year, 3.402 kilogram • Drug: MSK, Tablet, Unknown • Reactions: Weight loss, Medication error NOS, Vomiting, Not eating, Weakness… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-053375
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 15.00 Year
  • Weight: 3.402 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Tablet
Reactions Reported:
Weight loss Medication error NOS Vomiting Not eating Weakness Tiredness (lethargy) Elevated globulins Lymphopenia Abnormal radiograph finding Gastroenteritis Musculoskeletal disorder NOS Lack of efficacy - NOS
Outcomes: Ongoing

Cat, Domestic Shorthair, Male, 13 year, 6.35 kilogram • Drug: MSK, Unknown • Reactions: Hyperglycaemia, Elevated blood urea nitrogen, Poor coat condition, Weight loss, Hypochloraemia… • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-052366
  • Serious AE: No
  • Treated For AE: Yes
  • Sex: Male
  • Age: 13.00 Year
  • Weight: 6.350 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Hyperglycaemia Elevated blood urea nitrogen Poor coat condition Weight loss Hypochloraemia Polyuria Polydipsia
Outcomes: Outcome Unknown

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Overdose Information

No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.

Storage & Handling

Store at room temperature.

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