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Lokivetmab
Detailed information about Lokivetmab
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Sign in to continueReviewed / Updated / Sources
Reviewed: Not available
Updated: February 12, 2026, 7:40 PM UTC
- Medication contraindications · safety_warning
- openFDA case USA-USFDACVM-2025-US-053873 · adverse_reaction
Pet Owner Quick Guide
Start here first for the simple next-step summary.
Used for:
Monoclonal antibody used to reduce itch associated with atopic dermatitis in dogs.
What to watch for:
- Discuss use in dogs with a history of severe allergic reactions
- Tympanic rupture (1 reports)
- Pinnal ulcer (1 reports)
- Loss of hearing (1 reports)
When to call the vet:
- Repeated vomiting or diarrhea.
- Severe lethargy (hard to wake, very low energy).
- Collapse or fainting.
- Trouble breathing.
- Facial swelling or hives.
- Blood in vomit or stool.
What to ask your vet today:
- Is this medicine the right fit for my pet’s current symptoms?
- Which warning signs mean I should call back right away?
- How should I handle missed doses or refusal to take the medicine?
Safety & side effects
What to watch:
- Discuss use in dogs with a history of severe allergic reactions
- Tympanic rupture
- Pinnal ulcer
- Loss of hearing
Most reported reactions:
- Tympanic rupture (1 reports)
- Pinnal ulcer (1 reports)
- Loss of hearing (1 reports)
When to call your vet:
- Repeated vomiting or diarrhea.
- Severe lethargy (hard to wake, very low energy).
- Collapse or fainting.
- Trouble breathing.
Data freshness: source data appears current.
Latest refresh: Mar 21, 2026, 10:01 a.m.
- Medication catalog: Source Roxee | Refreshed Feb 12, 2026, 7:40 PM UTC
-
Animal Drug Product Listing Directory (NDC):
Source FDA
| Refreshed Mar 21, 2026, 10:01 AM UTC
Package/product NDCs from FDA’s electronic listing directory (XLS).
- openFDA reaction terms: Source FDA openFDA | Refreshed Mar 14, 2026, 10:04 AM UTC
- openFDA case summaries: Source FDA openFDA | Refreshed Feb 9, 2026, 3:19 AM UTC
Lokivetmab
Drug type: Generic ingredient • Generic profile • No FDA branded products linked
Species: Dog
Manufacturer: Not available (source)
Quick Facts
Official label facts first, then secondary summaries. Marketing content is separated below.
Warnings / Contraindications
Discuss use in dogs with a history of severe allergic reactions.
- High: Discuss use in dogs with a history of severe allergic reactions.
- https://animaldrugsatfda.fda.gov · safety_warning · Medication contraindications
Adverse Reactions
Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.
Tap or hover a reaction to see what it means in plain language.
Grouped by Body System
Most Reported Reactions
| Reaction | Body system | Cases | Species | Serious cases |
|---|---|---|---|---|
| Other | 1 | Dog | 1 | |
| Other | 1 | Dog | 1 | |
| Other | 1 | Dog | 1 | |
| Other | 1 | Dog | 1 | |
| Other | 1 | Dog | 1 | |
| Other | 1 | Dog | 0 | |
| Neurologic | 1 | Dog | 0 | |
| Other | 1 | Dog | 0 |
Species coverage: Dog (15)
View detailed reaction table
| Reaction | Body system | Species | Seriousness | Frequency | Reports |
|---|---|---|---|---|---|
| Other | Dog | Non-serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Neurologic | Dog | Non-serious | - | 1 | |
| Other | Dog | Non-serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Skin & allergy | Dog | Non-serious | - | 1 | |
| Other | Dog | Non-serious | - | 1 | |
| Other | Dog | Non-serious | - | 1 | |
| Other | Dog | Non-serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Dog | Non-serious | - | 1 | |
| Other | Dog | Non-serious | - | 1 | |
| Skin & allergy | Dog | Non-serious | - | 1 | |
| Other | Dog | Serious | - | 1 |
- https://api.fda.gov/animalandveterinary/event.json · adverse_reaction · openFDA case USA-USFDACVM-2025-US-053873
Storage & Handling
Refrigerate and protect from light; do not freeze.
Veterinary reference (advanced)
Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.
At a Glance
Quick facts and links to official labeling and safety signals.
- Medication catalog: Source Roxee | Refreshed Feb 12, 2026, 7:40 PM UTC
-
Animal Drug Product Listing Directory (NDC):
Source FDA
| Refreshed Mar 21, 2026, 10:01 AM UTC
Package/product NDCs from FDA’s electronic listing directory (XLS).
- openFDA reaction terms: Source FDA openFDA | Refreshed Mar 14, 2026, 10:04 AM UTC
- openFDA case summaries: Source FDA openFDA | Refreshed Feb 9, 2026, 3:19 AM UTC
Counseling and Monitoring Highlights
Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.
- Discuss use in dogs with a history of severe allergic reactions. (Contraindication, High)
Data Sources & Change Log
Every non-trivial field is expected to include provenance and update timestamps.
- contraindications: Discuss use in dogs with a history of severe allergic reactions. (Clinical, 2026-02-12)
- storage_handling: Refrigerate and protect from light; do not freeze. (Clinical, 2026-02-12)
- usage: Monoclonal antibody used to reduce itch associated with atopic dermatitis in dogs. (Clinical, 2026-02-12)
- side_effects: Injection site reactions, lethargy; generally well tolerated. (Official, 2026-02-12)
- side_effects updated 2026-02-12 19:40 by etl_backfill • Backfilled from existing medication fields
- contraindications updated 2026-02-12 19:40 by etl_backfill • Backfilled from existing medication fields
- usage updated 2026-02-12 19:40 by etl_backfill • Backfilled from existing medication fields
Usage
Monoclonal antibody used to reduce itch associated with atopic dermatitis in dogs.
Contraindications
Discuss use in dogs with a history of severe allergic reactions.
Side Effects
Injection site reactions, lethargy; generally well tolerated.
Source: FDA openFDA • Reference
Top Reported Reactions (openFDA)
De-duplicated reaction terms grouped by body system from FDA openFDA reports (not verified; does not prove causation).
Showing top 5 for Skin & allergy.
Showing top 5 for Neurologic.
Show more (7)
Showing top 5 for Other.
Data source: FDA openFDA Animal & Veterinary adverse event reports.
Adverse Event Case Summaries (openFDA)
These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.
Dog, Terrier - Fox Wire, Male, 10.8 year, 9.68 kilogram • Drug: MSK, Subcutaneous, Dose: 30 Milligram per animal, Frequency: 1 per month • Reactions: Deafness, Tympanic rupture, Application site discharge NOS • Outcome: Outcome Unknown
- Report ID: USA-USFDACVM-2025-US-053873
- Serious AE: Yes
- Treated For AE: No
- Sex: Male
- Age: 10.80 Year
- Weight: 9.680 Kilogram
- Case-reported brand: MSK
- Case-reported manufacturer: MSK
- Route: Subcutaneous
- Dose: 30 Milligram per animal
- Frequency: 1 per month
Dog, Shih Tzu, Female, 8 year, 4.627 kilogram • Drug: MSK, Injection, Unknown, Dose: 1 dose per animal, Frequency: 1 per day • Reactions: Pinnal ulcer • Outcome: Recovered/Normal
- Report ID: USA-USFDACVM-2025-US-052998
- Serious AE: Yes
- Treated For AE: No
- Sex: Female
- Age: 8.00 Year
- Weight: 4.627 Kilogram
- Case-reported brand: MSK
- Case-reported manufacturer: MSK
- Route: Unknown
- Form: Injection
- Dose: 1 dose per animal
- Frequency: 1 per day
Dog, Cattle Dog - Flanders (Bouvier), Female, 10 year, 61.2 kilogram • Drug: MSK, Subcutaneous, Dose: 1 dose per animal • Reactions: Inappropriate urination, Pollakiuria, Blood in urine, Unclassifiable adverse event, Female reproductive tract disorder NOS… • Outcome: Outcome Unknown
- Report ID: USA-USFDACVM-2025-US-050192
- Serious AE: No
- Treated For AE: No
- Sex: Female
- Age: 10.00 Year
- Weight: 61.200 Kilogram
- Case-reported brand: MSK
- Case-reported manufacturer: MSK
- Route: Subcutaneous
- Dose: 1 dose per animal
Dog, ['Terrier - Yorkshire', 'Dog (unknown)'], Female, 11 year, 4.1 kilogram • Drug: MSK, Injection, Subcutaneous • Reactions: Loss of hearing • Outcome: Recovered/Normal
- Report ID: USA-USFDACVM-2025-US-049475
- Serious AE: Yes
- Treated For AE: Yes
- Sex: Female
- Age: 11.00 Year
- Weight: 4.100 Kilogram
- Case-reported brand: MSK
- Case-reported manufacturer: MSK
- Route: Subcutaneous
- Form: Injection
Dog, Terrier - Rat, Female, 6 year, 9.1 kilogram • Drug: MSK, Injection, Subcutaneous • Reactions: Application site reddening, Application site itching • Outcome: Recovered/Normal
- Report ID: USA-USFDACVM-2025-US-051027
- Serious AE: No
- Treated For AE: No
- Sex: Female
- Age: 6.00 Year
- Weight: 9.100 Kilogram
- Case-reported brand: MSK
- Case-reported manufacturer: MSK
- Route: Subcutaneous
- Form: Injection
Data source: FDA openFDA Animal & Veterinary adverse event reports.
Overdose Information
No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.
Storage & Handling
Refrigerate and protect from light; do not freeze.
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This medication has not been reviewed by a veterinarian yet.