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Fluralaner Spot-On Solution

Detailed information about Fluralaner Spot-On Solution

Official label facts Owner quick guide first Marketing clearly labeled
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Reviewed / Updated / Sources

Reviewed: Not available

Updated: February 12, 2026, 10:44 PM UTC

Sources:

Pet Owner Quick Guide

Start here first for the simple next-step summary.

Used for:

Your vet decides this. Here's what owners typically ask/watch for.

What to watch for:

  • Wheezing (1 reports)
  • Vomiting (1 reports)
  • Vocalisation (1 reports)

When to call the vet:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
  • Facial swelling or hives.
  • Blood in vomit or stool.

What to ask your vet today:

  • Is this medicine the right fit for my pet’s current symptoms?
  • Which warning signs mean I should call back right away?
  • How should I handle missed doses or refusal to take the medicine?
Safety & side effects

What to watch:

  • Wheezing
  • Vomiting
  • Vocalisation

Most reported reactions:

  • Wheezing (1 reports)
  • Vomiting (1 reports)
  • Vocalisation (1 reports)

When to call your vet:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
Talk to a Vet / Find a Vet Near You Start Symptom Intake

Data freshness: source data appears current.

Latest refresh: Mar 21, 2026, 10:01 a.m.

Data freshness
  • Medication catalog: Source Roxee | Refreshed Feb 12, 2026, 10:44 PM UTC
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed Mar 21, 2026, 10:01 AM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
  • openFDA reaction terms: Source FDA openFDA | Refreshed Mar 16, 2026, 10:04 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Feb 12, 2026, 10:42 PM UTC
Image coming soon
Fluralaner Spot-On Solution

Fluralaner Spot-On Solution

Drug type: Generic ingredient • Generic profile • No FDA branded products linked

Species: Both

Manufacturer: Not available (source)

Quick Facts

Official label facts first, then secondary summaries. Marketing content is separated below.

Species: Both
Manufacturer: Not available

Adverse Reactions

Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.

Tap or hover a reaction to see what it means in plain language.

Tracked signals
29
Reported cases
26
Serious reports
17
Species represented
2
Grouped by Body System
Digestive (2) · Vomiting, Decreased appetite Skin & allergy (2) · Application site hair loss, Hair loss at application site Neurologic (1) · Tiredness (lethargy) Behavior (1) · Behavioral disorder (unspecified) Effectiveness (2) · Lack of efficacy (endoparasite) - tapeworm, Lack of efficacy (ectoparasite) - flea Other (21) · Wheezing, Vocalisation, Sneezing
Most Reported Reactions
Reaction Body system Cases Species Serious cases
Other 1 Cat 1
Digestive 1 Cat 1
Other 1 Cat 1
Neurologic 1 Cat 1
Other 1 Cat 1
Other 1 Cat 1
Other 1 Cat 1
Effectiveness 1 Dog 1

Species coverage: Cat (22) Dog (7)

View detailed reaction table
Reaction Body system Species Seriousness Frequency Reports
Other Cat Serious - 1
Digestive Cat Serious - 1
Other Cat Serious - 1
Neurologic Cat Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Dog Non-serious - 1
Effectiveness Dog Serious - 1
Effectiveness Dog Non-serious - 1
Other Cat Serious - 1
Other Dog Non-serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Dog Non-serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Digestive Cat Serious - 1
Behavior Cat Serious - 1
Other Cat Non-serious - 1
Skin & allergy Cat Non-serious - 1
Other Cat Non-serious - 1
Other Cat Non-serious - 1
Other Dog Non-serious - 1
Skin & allergy Cat Unknown - -
Other Cat Unknown - -
Other Dog Unknown - -
Source metadata:
Veterinary reference (advanced)

Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.

At a Glance

Quick facts and links to official labeling and safety signals.

Data freshness
  • Medication catalog: Source Roxee | Refreshed Feb 12, 2026, 10:44 PM UTC
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed Mar 21, 2026, 10:01 AM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
  • openFDA reaction terms: Source FDA openFDA | Refreshed Mar 16, 2026, 10:04 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Feb 12, 2026, 10:42 PM UTC
Official (FDA)
Identity: Generic ingredient • No FDA branded products linked
No official FDA brand rows linked yet for this ingredient.
Case-reported brands (openFDA): MSK
Catalog species: Both
Safety (openFDA)
Top reactions: Dog 27 • Cat 21 • View
Case summaries: 12 (showing 8) • View
openFDA reports are unverified and do not prove causation.
Diagnosis Codes

Diagnosis-code mappings are not available for this medication yet.

Counseling and Monitoring Highlights

Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.

Top reaction signals
Wheezing (1) Vomiting (1) Vocalisation (1) Tiredness (lethargy) (1) Sneezing (1) Overdose (1) Ocular discharge (1) Lack of efficacy (endoparasite) - tapeworm (1)

Data Sources & Change Log

Every non-trivial field is expected to include provenance and update timestamps.

Official 1 Clinical 0 Manufacturer 0 Marketing 0
Current Field Facts
  • side_effects: Top reported reactions (openFDA): Lack of efficacy (ectoparasite) - flea, Lack of efficacy (ectoparasite) - tick NOS, Lethargy (see also Central nervous system… (Official, 2026-02-12)
Recent Revisions
  • side_effects updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields

Top Reported Reactions (openFDA)

De-duplicated reaction terms grouped by body system from FDA openFDA reports (not verified; does not prove causation).

Digestive
Vomiting (1) • Cat Decreased appetite (1) • Cat

Showing top 5 for Digestive.

Skin & allergy
Application site hair loss (1) • Cat Hair loss at application site • Cat

Showing top 5 for Skin & allergy.

Neurologic
Tiredness (1) • Cat

Showing top 5 for Neurologic.

Behavior
Behavioral disorder (1) • Cat

Showing top 5 for Behavior.

Effectiveness
Lack of efficacy (endoparasite) - tapeworm (1) • Dog Lack of efficacy (ectoparasite) - flea (1) • Dog

Showing top 5 for Effectiveness.

Other
Wheezing (1) • Cat Vocalisation (1) • Cat Sneezing (1) • Cat Overdose (1) • Cat Ocular discharge (1) • Cat
Show more (16)
Medication error NOS (1) • Dog Intentional misuse (1) • Cat Injection site lump (1) • Dog Excessive chewing, licking and/or grooming (1) • Cat Elevated temperature (1) • Cat Difficulty standing (1) • Dog Dehydration (1) • Cat Decreased urine concentration (1) • Cat Decreased haematocrit (1) • Cat Decreased drinking (1) • Cat Application site scab (1) • Cat Application site burn (1) • Cat Application site blister (1) • Cat Administration error NOS (1) • Dog Appearance, Abnormal • Cat Anaphylaxis • Dog

Showing top 5 for Other.

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Adverse Event Case Summaries (openFDA)

These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.

Cat, Domestic Shorthair, Male, 6 year, 3.221 kilogram • Drug: MSK, Solution, Topical, Dose: 250 Milligram per animal • Reactions: Excessive chewing, licking and/or grooming, Vocalisation, Tiredness (lethargy), Decreased appetite, Decreased drinking… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-056023
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 6.00 Year
  • Weight: 3.221 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Topical
  • Form: Solution
  • Dose: 250 Milligram per animal
Reactions Reported:
Excessive chewing, licking and/or grooming Vocalisation Tiredness (lethargy) Decreased appetite Decreased drinking Behavioral disorder (unspecified) Dehydration Intentional misuse
Outcomes: Ongoing

Cat, Domestic Shorthair, Male, 14 year, 4.536 kilogram • Drug: MSK, Solution, Topical, Dose: 250 Milligram per animal • Reactions: Lack of efficacy (ectoparasite) - flea • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-056028
  • Serious AE: No
  • Treated For AE: No
  • Sex: Male
  • Age: 14.00 Year
  • Weight: 4.536 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Topical
  • Form: Solution
  • Dose: 250 Milligram per animal
Reactions Reported:
Lack of efficacy (ectoparasite) - flea
Outcomes: Ongoing

Cat, Domestic Shorthair, Female, 14 year, 4.4 kilogram • Drug: MSK, Solution, Topical, Dose: 250 Milligram per animal • Reactions: Lack of efficacy (ectoparasite) - flea • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-056027
  • Serious AE: No
  • Treated For AE: No
  • Sex: Female
  • Age: 14.00 Year
  • Weight: 4.400 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Topical
  • Form: Solution
  • Dose: 250 Milligram per animal
Reactions Reported:
Lack of efficacy (ectoparasite) - flea
Outcomes: Ongoing

Cat, Cat (unknown), Male, 3.175 kilogram • Drug: MSK, Solution, Topical, Dose: 500 Milligram per animal • Reactions: Lack of efficacy (ectoparasite) - flea, Vomiting, Overdose • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-056026
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Weight: 3.175 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Topical
  • Form: Solution
  • Dose: 500 Milligram per animal
Reactions Reported:
Lack of efficacy (ectoparasite) - flea Vomiting Overdose
Outcomes: Ongoing

Cat, Domestic Shorthair, Female, 2 year, 4.536 kilogram • Drug: MSK, Solution, Topical, Dose: 1 Vial per animal, Frequency: 3 per month • Reactions: Application site hair loss, Application site burn, Application site blister, Application site scab • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2025-US-056022
  • Serious AE: No
  • Treated For AE: No
  • Sex: Female
  • Age: 2.00 Year
  • Weight: 4.536 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Topical
  • Form: Solution
  • Dose: 1 Vial per animal
  • Frequency: 3 per month
Reactions Reported:
Application site hair loss Application site burn Application site blister Application site scab
Outcomes: Recovered/Normal

Cat, Domestic Longhair, Female, 12 year, 7.031 kilogram • Drug: MSK, Solution, Topical, Dose: 500 Milligram per animal • Reactions: Tiredness (lethargy), Decreased appetite, Wheezing, Sneezing, Ocular discharge… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-056021
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 12.00 Year
  • Weight: 7.031 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Topical
  • Form: Solution
  • Dose: 500 Milligram per animal
Reactions Reported:
Tiredness (lethargy) Decreased appetite Wheezing Sneezing Ocular discharge Elevated temperature Lack of efficacy (ectoparasite) - flea Decreased haematocrit Decreased urine concentration
Outcomes: Ongoing

Dog, Siberian Husky, Female, 6 year, 30.754 kilogram • Drug: MSK, Solution, Topical, Dose: 1000 Milligram per animal, Frequency: 3 per month • Reactions: Lack of efficacy (ectoparasite) - flea • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-056024
  • Serious AE: No
  • Treated For AE: No
  • Sex: Female
  • Age: 6.00 Year
  • Weight: 30.754 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Topical
  • Form: Solution
  • Dose: 1000 Milligram per animal
  • Frequency: 3 per month
Reactions Reported:
Lack of efficacy (ectoparasite) - flea
Outcomes: Ongoing

Dog, ['Crossbred Canine/dog', 'Shepherd Dog - Australian'], Male, 4 year, 36.287 kilogram • Drug: MSK, Solution, Subcutaneous • Reactions: Medication error NOS, Administration error NOS, Injection site lump • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-056019
  • Serious AE: No
  • Treated For AE: No
  • Sex: Male
  • Age: 4.00 Year
  • Weight: 36.287 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Subcutaneous
  • Form: Solution
Reactions Reported:
Medication error NOS Administration error NOS Injection site lump
Outcomes: Ongoing

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Overdose Information

No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.

Storage & Handling

No approved storage guidance is linked yet for this ingredient. Use manufacturer packaging and veterinary guidance for handling/storage.

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