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Firocoxib

Detailed information about Firocoxib

Official label facts Owner quick guide first Marketing clearly labeled
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Reviewed / Updated / Sources

Reviewed: Not available

Updated: February 12, 2026, 10:44 PM UTC

Sources:

Pet Owner Quick Guide

Start here first for the simple next-step summary.

Used for:

For the control of pain and inflammation associated with osteoarthritis.

What to watch for:

  • Do not use in horses intended for human consumption
  • For intravenous use in horses only
  • Vomiting (1 reports)
  • very low energy (1 reports)
  • Overdose (1 reports)

When to call the vet:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
  • Facial swelling or hives.
  • Blood in vomit or stool.

Regulatory restrictions are shown in Vet View.

What to ask your vet today:

  • Is this medicine the right fit for my pet’s current symptoms?
  • Which warning signs mean I should call back right away?
  • How should I handle missed doses or refusal to take the medicine?
Safety & side effects

What to watch:

  • Do not use in horses intended for human consumption
  • For intravenous use in horses only
  • Vomiting
  • very low energy
  • Overdose

Most reported reactions:

  • Vomiting (1 reports)
  • Tiredness (lethargy) (1 reports)
  • Overdose (1 reports)

When to call your vet:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
Talk to a Vet / Find a Vet Near You Start Symptom Intake

Data freshness: source data appears current.

Latest refresh: Mar 21, 2026, 10:01 a.m.

Data freshness
  • Medication catalog: Source Roxee | Refreshed Feb 12, 2026, 10:44 PM UTC
  • Animal Drugs @ FDA: Source FDA | Refreshed Mar 21, 2026, 10:00 AM UTC
    Applications/products are imported from FDA export data.
  • Animal Drugs @ FDA previews: Source FDA | Refreshed Mar 3, 2026, 11:00 AM UTC
    Label highlights/doc links are fetched from FDA preview endpoints.
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed Mar 21, 2026, 10:01 AM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
  • openFDA reaction terms: Source FDA openFDA | Refreshed Mar 16, 2026, 10:04 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Feb 9, 2026, 3:20 AM UTC
Image coming soon
Firocoxib

Firocoxib

Drug type: Generic ingredient • Branded profile • FDA branded products available

Species: Both

Manufacturer: Boehringer lngelheim Animal Health USA, Inc.

Quick Facts

Official label facts first, then secondary summaries. Marketing content is separated below.

Species: Both
Manufacturer: Boehringer lngelheim Animal Health USA, Inc.
Form: Chewable Tablets, Non-Aqueous Injectable Solution, Oral Solution, Paste, Tablet
Identifiers:
ANADA: 200722 ANADA: 200726 ANADA: 200751 ANADA: 200755 ANADA: 200756 ANADA: 200766 ANADA: 200841 NADA: 141230 NADA: 141253 NADA: 141313 NADA: 141458 NDC Package: 0010-3309-01 NDC Package: 0010-3309-02 NDC Package: 0010-9140-02 NDC Package: 0010-9140-03 NDC Package: 0010-9140-06 NDC Package: 0010-9150-02 NDC Package: 0010-9150-03 NDC Package: 0010-9150-05 NDC Package: 11695-7018-1
Source metadata:

Warnings / Contraindications

Federal law restricts this drug to use by or on the order of a licensed veterinarian. Do not use in horses intended for human consumption. Federal law restricts this drug to use by or on the order of a licensed veterinarian. Do not use in horses intended for human consumption. Federal law restricts this drug to use by or on the order of a licensed veterinarian. For intravenous use in horses only.

  • High: Federal law restricts this drug to use by or on the order of a licensed veterinarian. Do not use in horses intended for human consumption. Federal law restricts this drug to use by or on the order of a licensed veterinarian. Do not use in horses intended for human consumption. Federal law restricts this drug to use by or on the order of a licensed veterinarian. For intravenous use in horses only.
Source metadata:

Adverse Reactions

Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.

Tap or hover a reaction to see what it means in plain language.

Tracked signals
32
Reported cases
32
Serious reports
28
Species represented
2
Grouped by Body System
Digestive (2) · Vomiting, Loss of appetite Neurologic (2) · Unsteady walking (ataxia), Tiredness (lethargy) Effectiveness (1) · Lack of efficacy - NOS Other (27) · Overdose, Other abnormal test result NOS, Not drinking
Most Reported Reactions
Reaction Body system Cases Species Serious cases
Digestive 1 Dog 1
Neurologic 1 Dog 1
Other 1 Dog 1
Other 1 Cat 1
Other 1 Dog 1
Other 1 Dog 1
Other 1 Dog 1
Digestive 1 Dog 1

Species coverage: Dog (25) Cat (7)

View detailed reaction table
Reaction Body system Species Seriousness Frequency Reports
Digestive Dog Serious - 1
Neurologic Dog Non-serious - 1
Neurologic Dog Serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Other Dog Serious - 1
Other Dog Non-serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Digestive Dog Serious - 1
Other Cat Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Effectiveness Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Cat Non-serious - 1
Other Dog Serious - 1
Other Dog Non-serious - 1
Other Dog Serious - 1
Source metadata:

Documents

Owner handouts and official technical documents are grouped for faster access.

Owner handouts (0)
  • No owner handouts linked yet.
Official label / PI (15)
SPL (11)
  • Firocoxib Tablets for Horses · SPL
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/spl/file/18470/Firocoxib%20Tablets%20for%20Horses
  • Firocoxib · SPL
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/spl/file/14554/Firocoxib
  • Previcox® · SPL
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/spl/file/268/Previcox%C2%AE
  • EquiCoxib™ · SPL
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/spl/file/15183/EquiCoxib%E2%84%A2
  • Firocoxib Chewable Tablets for Dogs · SPL
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/spl/file/14422/Firocoxib%20Chewable%20Tablets%20for%20Dogs
  • Firodyl™ · SPL
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/spl/file/14556/Firodyl%E2%84%A2
  • Firox™ · SPL
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/spl/file/12217/Firox%E2%84%A2
  • Firocoxib Tablets for Horses · SPL
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/spl/file/12807/Firocoxib%20Tablets%20for%20Horses
  • Equioxx® Oral Paste · SPL
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/spl/file/315/Equioxx%C2%AE%20Oral%20Paste
  • Equioxx® · SPL
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/spl/file/2567/Equioxx%C2%AE
  • Equioxx® Injection · SPL
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/spl/file/2201/Equioxx%C2%AE%20Injection
FOI (13)
Source metadata:
Veterinary reference (advanced)

Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.

At a Glance

Quick facts and links to official labeling and safety signals.

Data freshness
  • Medication catalog: Source Roxee | Refreshed Feb 12, 2026, 10:44 PM UTC
  • Animal Drugs @ FDA: Source FDA | Refreshed Mar 21, 2026, 10:00 AM UTC
    Applications/products are imported from FDA export data.
  • Animal Drugs @ FDA previews: Source FDA | Refreshed Mar 3, 2026, 11:00 AM UTC
    Label highlights/doc links are fetched from FDA preview endpoints.
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed Mar 21, 2026, 10:01 AM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
  • openFDA reaction terms: Source FDA openFDA | Refreshed Mar 16, 2026, 10:04 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Feb 9, 2026, 3:20 AM UTC
Official (FDA)
Identity: Generic ingredient • FDA branded products available
Official FDA brands: EquiCoxib™ Equioxx® Equioxx® Injection Equioxx® Oral Paste Firocoxib Firocoxib Chewable Tablets for Dogs Firocoxib Tablets for Horses Firodyl™ Firox™ Previcox®
Case-reported brands (openFDA): MSK
Catalog species: Both • FDA-labeled species: Dog, Horse, No Use Class Stated Or Implied
Rx/OTC: RX
Form/route: Chewable Tablets, Non-Aqueous Injectable Solution, Oral Solution, Paste, Tablet • Intravenous, Oral
Applications: ANADA 200-841 • ANADA 200-755 • NADA 141-230 • ANADA 200-766 • ANADA 200-751 • ANADA 200-756 • ANADA 200-722 • ANADA 200-726 • NADA 141-253 • NADA 141-458 • NADA 141-313
NDC: Packages 11695-7018-1 11695-7018-2 11695-7019-1 11695-7019-2 51604-1190-0 71052-020-50 • Products 11695 11695 11695 11695 51604 71052
Documents: 28 (FOI: 13) • SPL: 11 • Label highlights • Official documents
Safety (openFDA)
Top reactions: Dog 22 • Cat 8 • View
Case summaries: 10 (showing 8) • View
openFDA reports are unverified and do not prove causation.
Explore
Linked using: Fda_Label (0.95), Fda_Label (0.95), Fda_Label (0.95)
Diagnosis Codes
ICD10_CM: M19.90
Unspecified osteoarthritis, unspecified site

Counseling and Monitoring Highlights

Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.

Owner-facing counseling points
  • Federal law restricts this drug to use by or on the order of a licensed veterinarian. Do not use in horses intended for human consumption. Federal law restricts this drug to use by or on the order of a licensed veterinarian. Do not use in horses intended for human consumption. Federal law restricts this drug to use by or on the order of a licensed veterinarian. For intravenous use in horses only. (Contraindication, High)
Top reaction signals
Vomiting (1) Tiredness (lethargy) (1) Overdose (1) Other abnormal test result NOS (1) Not drinking (1) Malaise (1) Lymphopenia (1) Loss of appetite (1)

Identifiers & Packages

Normalized identifiers (NDC/NADA/ANADA) and package metadata from regulator listings.

Identifiers
ANADA: 200722 ANADA: 200726 ANADA: 200751 ANADA: 200755 ANADA: 200756 ANADA: 200766 ANADA: 200841 NADA: 141230 NADA: 141253 NADA: 141313 NADA: 141458 NDC Package: 0010-3309-01 NDC Package: 0010-3309-02 NDC Package: 0010-9140-02 NDC Package: 0010-9140-03 NDC Package: 0010-9140-06 NDC Package: 0010-9150-02 NDC Package: 0010-9150-03 NDC Package: 0010-9150-05 NDC Package: 11695-7018-1 NDC Package: 11695-7018-2 NDC Package: 11695-7019-1 NDC Package: 11695-7019-2 NDC Package: 17033-720-18
Package NDC Product NDC Form / Route Status
0010-3309-01 0010 -
0010-3309-02 0010 -
0010-9140-02 0010 -
0010-9140-03 0010 -
0010-9140-06 0010 -
0010-9150-02 0010 -
0010-9150-03 0010 -
0010-9150-05 0010 -
11695-7018-1 11695 -
11695-7018-2 11695 -
11695-7019-1 11695 -
11695-7019-2 11695 -
17033-720-18 17033 -
17033-720-60 17033 -
17033-721-18 17033 -
17033-721-60 17033 -
46066-177-38 46066 -
46066-177-39 46066 -
46066-179-38 46066 -
46066-179-39 46066 -

Enriched Documents

Documents are tiered by source trust: Official, Clinical, Manufacturer, Marketing.

Data Sources & Change Log

Every non-trivial field is expected to include provenance and update timestamps.

Official 31 Clinical 0 Manufacturer 0 Marketing 0
Current Field Facts
  • contraindications: Federal law restricts this drug to use by or on the order of a licensed veterinarian. Do not use in horses intended for human consumption. Federal law restrict… (Official, 2026-02-12)
  • side_effects: Top reported reactions (openFDA): Vomiting, Lethargy (see also Central nervous system depression in 'Neurological'), Diarrhoea, Elevated blood urea nitrogen (B… (Official, 2026-02-12)
  • usage: For the control of pain and inflammation associated with osteoarthritis and for the control of postoperative pain and inflammation associated with soft-tissue … (Official, 2026-02-12)
Recent Revisions
  • side_effects updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields
  • usage updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields

FDA Products & Applications (Animal Drugs @ FDA)

Official sponsor/proprietary-name/application-status records linked by active ingredient.

Product Sponsor Application Status Published
Firocoxib Tablets for Horses
RX
Firocoxib
Tablet • Oral
Label highlights
Official documents
Felix Pharmaceuticals Pvt. Ltd. ANADA 200-841 Approved Mar 2, 2026
Firocoxib
RX
Firocoxib
Chewable Tablets • Oral
Label highlights
Official documents
Felix Pharmaceuticals Pvt. Ltd. ANADA 200-755 Approved Apr 24, 2025
Previcox®
RX
Firocoxib
Chewable Tablets • Oral
Label highlights
Official documents
Boehringer lngelheim Animal Health USA, Inc. NADA 141-230 Approved Apr 24, 2025
EquiCoxib™
RX
Firocoxib
Oral Solution • Oral
Label highlights
Official documents
Aurora Pharmaceutical, Inc. ANADA 200-766 Approved Oct 3, 2024
Firocoxib Chewable Tablets for Dogs
RX
Firocoxib
Chewable Tablets • Oral
Label highlights
Official documents
Pegasus Laboratories, Inc. ANADA 200-751 Approved Mar 4, 2024
Firodyl™
RX
Firocoxib
Chewable Tablets • Oral
Label highlights
Official documents
Ceva Sante Animale ANADA 200-756 Approved Sep 1, 2023
Firox™
RX
Firocoxib
Chewable Tablets • Oral
Label highlights
Official documents
Norbrook Laboratories, Ltd. ANADA 200-722 Approved Nov 2, 2022
Firocoxib Tablets for Horses
RX
Firocoxib
Tablet • Oral
Label highlights
Official documents
Pegasus Laboratories, Inc. ANADA 200-726 Approved Aug 1, 2022
Equioxx® Oral Paste
RX
Firocoxib
Paste • Oral
Label highlights
Official documents
Boehringer lngelheim Animal Health USA, Inc. NADA 141-253 Approved Apr 8, 2020
Equioxx®
RX
Firocoxib
Tablet • Oral
Label highlights
Official documents
Boehringer lngelheim Animal Health USA, Inc. NADA 141-458 Approved Dec 17, 2019
Equioxx® Injection
RX
Firocoxib
Non-Aqueous Injectable Solution • Intravenous
Label highlights
Official documents
Boehringer lngelheim Animal Health USA, Inc. NADA 141-313 Approved Nov 13, 2017

Data source: FDA Animal Drugs @ FDA (public search export).

What It's For (FDA Label Highlights)

Extracted from FDA Animal Drugs @ FDA product labeling. Always confirm details with your veterinarian.

Composition / specifications
57 mg firocoxib per tablet
Horses
Indication

For the control of pain and inflammation associated with osteoarthritis.

Dosage

Administer one 57-mg tablet to horses weighing 800 to 1,300 lb once daily for up to 14 days.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Dog, No Use Class Stated Or Implied
Composition / specifications
57 mg or 227 mg of firocoxib per tablet
Dogs
Indication

For the control of pain and inflammation associated with osteoarthritis; and for the control of postoperative pain and inflammation associated with soft-tissue and orthopedic surgery.

Dosage

5 mg/kg (2.27 mg/lb) body weight. Administer once daily as needed for osteoarthritis and for 3 days as needed for postoperative pain and inflammation associated with soft-tissue and orthopedic surgery. Administer approximately 2 hours before soft-tissue or orthopedic surgery.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Dog, No Use Class Stated Or Implied
Composition / specifications
Each chewable tablet contains 57 or 227 mg firocoxib.
Dogs
Indication
For the control of pain and inflammation associated with osteoarthritis and for the control of postoperative pain and inflammation associated with soft-tissue and orthopedic surgery in dogs.
Dosage
5 mg/kg (2.27 mg/lb) body weight once daily as needed for osteoarthritis and for 3 days as needed for postoperative pain and inflammation associated with soft-tissue and orthopedic surgery. Administer approximately 2 hours prior to surgery.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian.

FDA page: Open in Animal Drugs @ FDA

Species: No Use Class Stated Or Implied
Composition / specifications
9.0 mg/mL
Horses
Indication

For the control of pain and inflammation associated with osteoarthritis in horses.

Dosage

0.045 mg/lb (0.1 mg/kg) of body weight once daily for up to 14 days

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Dog, No Use Class Stated Or Implied
Composition / specifications
57 mg or 227 mg of firocoxib per tablet
Dogs
Indication

For the control of pain and inflammation associated with osteoarthritis and for the control of postoperative pain and inflammation associated with soft-tissue and orthopedic surgery in dogs.

Dosage

5 mg/kg (2.27 mg/lb) body weight. Administer once daily as needed for osteoarthritis and for 3 days as needed for postoperative pain and inflammation associated with soft-tissue and orthopedic surgery. Administer approximately 2 hours before soft-tissue or orthopedic surgery.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Dog, No Use Class Stated Or Implied
Composition / specifications
57 mg and 227 mg of firocoxib per tablet
Dogs
Indication

For the control of pain and inflammation associated with osteoarthritis and for the control of postoperative pain and inflammation associated with soft-tissue and orthopedic surgery.

Dosage

5 mg/kg (2.27 mg/lb) body weight. Administer once daily as needed for osteoarthritis and for 3 days as needed for postoperative pain and inflammation associated with soft-tissue and orthopedic surgery. Administer approximately 2 hours before soft-tissue or orthopedic surgery.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Dog, No Use Class Stated Or Implied
Composition / specifications
57 mg and 227 mg of firocoxib per tablet
Dogs
Indication

For the control of pain and inflammation associated with osteoarthritis and for the control of postoperative pain and inflammation associated with soft-tissue and orthopedic surgery in dogs.

Dosage

2.27 mg/lb (5.0 mg/kg) body weight once daily as needed for osteoarthritis and for 3 days as needed for postoperative pain and inflammation associated with soft-tissue and orthopedic surgery. Administer approximately 2 hours prior to surgery.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: No Use Class Stated Or Implied
Composition / specifications
57 mg firocoxib per tablet
Horses
Indication

For the control of pain and inflammation associated with osteoarthritis in horses.

Dosage

One 57 mg tablet administered orally to horses weighing 800 – 1300 lbs, once daily for up to 14 days.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Horse, Not For Meat Production
Composition / specifications
Each milligram (mg) of paste contains 0.82 mg firocoxib.
Horses
Indication
For the control of pain and inflammation associated with osteoarthritis.
Dosage
0.1 mg per kilogram (0.045 mg per pound) body weight daily for up to 14 days.
Limitations
Do not use in horses intended for human consumption. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

FDA page: Open in Animal Drugs @ FDA

Species: No Use Class Stated Or Implied
Composition / specifications
57 mg firocoxib
Horses
Indication
For the control of pain and inflammation associated with osteoarthritis in horses.
Dosage
Administer one 57 mg tablet daily for horses weighing 800-1300 lbs for up to 14 days duration.
Limitations
For use in horses only. Do not use in horses intended for human consumption.

FDA page: Open in Animal Drugs @ FDA

Species: No Use Class Stated Or Implied
Composition / specifications
20 mg firocoxib per mL
Horses
Indication
For the control of pain and inflammation associated with osteoarthritis in horses.
Dosage
One intravenous injection once daily for up to 5 days, at a dose of 0.04 mg/lb (0.09 mg/kg) body weight (BW). If further treatment is needed EQUIOXX (firocoxib) Oral Paste for horses can be used at a dosage of 0.045 mg/lb (0.1 mg/kg) body weight for up to an additional 9 days of treatment. The overall duration of treatment EQUIOXX Injection and EQUIOXX Oral Paste will be dependent on the response observed, but should not exceed 14 days.
Limitations
Do not use in horses intended for human consumption. Federal law restricts this drug to use by or on the order of a licensed veterinarian. For intravenous use in horses only.

FDA page: Open in Animal Drugs @ FDA

Official Documents (FDA)

Direct links to FDA-hosted PDFs and SPL packages (when available).

Documents
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    This supplement provides for the addition of a new indication for the control of postoperative pain and inflammation associated with orthopedic surgery in dogs.
  • Summary
    This supplement provides for the addition of a new indication for the control of postoperative pain and inflammation associated with soft-tissue surgery in dogs.
  • Summary
    For the control of pain and inflammation associated with osteoarthritis in dogs.
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Usage

For the control of pain and inflammation associated with osteoarthritis and for the control of postoperative pain and inflammation associated with soft-tissue and orthopedic surgery in dogs. For the control of pain and inflammation associated with osteoarthritis. For the control of pain and inflammation associated with osteoarthritis in horses.

Source: FDA Animal Drugs @ FDA • Reference

Contraindications

Federal law restricts this drug to use by or on the order of a licensed veterinarian. Do not use in horses intended for human consumption. Federal law restricts this drug to use by or on the order of a licensed veterinarian. Do not use in horses intended for human consumption. Federal law restricts this drug to use by or on the order of a licensed veterinarian. For intravenous use in horses only.

Top Reported Reactions (openFDA)

De-duplicated reaction terms grouped by body system from FDA openFDA reports (not verified; does not prove causation).

Digestive
Vomiting (1) • Dog Loss of appetite (1) • Dog

Showing top 5 for Digestive.

Neurologic
Unsteady walking (1) • Dog Tiredness (1) • Dog

Showing top 5 for Neurologic.

Effectiveness
Lack of efficacy - NOS (1) • Dog

Showing top 5 for Effectiveness.

Other
Overdose (1) • Dog Other abnormal test result NOS (1) • Cat Not drinking (1) • Dog Musculoskeletal disorder NOS (1) • Dog Malaise (1) • Dog
Show more (22)
Lymphopenia (1) • Dog Limb non-weight bearing (1) • Cat Leucopenia NOS (1) • Dog Leucocytosis NOS (1) • Dog Hyperthermia (1) • Dog Haematuria (1) • Dog Gastric ulcer (1) • Dog Fluid in abdomen NOS (1) • Dog Faecal incontinence (1) • Dog Facial paralysis (1) • Dog Facial palsy (1) • Dog Elevated liver enzymes NOS (1) • Cat Elevated creatinine (1) • Dog Elevated blood urea nitrogen (1) • Dog Death by euthanasia (1) • Cat Death (1) • Dog Cold feeling of extremity (1) • Cat Administration error NOS (1) • Cat Accidental exposure (1) • Cat Abnormal ultrasound finding (1) • Dog Abnormal radiograph finding (1) • Dog Abdominal pain (1) • Dog

Showing top 5 for Other.

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Adverse Event Case Summaries (openFDA)

These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.

Dog, Retriever - Labrador, Male, 11 year, 47.174 kilogram • Drug: MSK, Tablet, chewable, Oral, Dose: 4.81 Milligram per kilogram, Frequency: 1 per day • Reactions: Unsteady walking (ataxia), Abnormal radiograph finding, Musculoskeletal disorder NOS • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-056163
  • Serious AE: No
  • Treated For AE: Yes
  • Sex: Male
  • Age: 11.00 Year
  • Weight: 47.174 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet, chewable
  • Dose: 4.81 Milligram per kilogram
  • Frequency: 1 per day
Reactions Reported:
Unsteady walking (ataxia) Abnormal radiograph finding Musculoskeletal disorder NOS
Outcomes: Ongoing

Dog, Crossbred Canine/dog, Male, 10 year, 33.112 kilogram • Drug: MSK, Tablet, Oral • Reactions: Urinary incontinence, Faecal incontinence, Tiredness (lethargy), Tremors, Loss of appetite… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-054275
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 10.00 Year
  • Weight: 33.112 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet
Reactions Reported:
Urinary incontinence Faecal incontinence Tiredness (lethargy) Tremors Loss of appetite Sedation prolonged Leucopenia NOS Lymphopenia Lack of efficacy - NOS Unable to walk Pyuria Haematuria Urinary tract infection
Outcomes: Ongoing

Dog, Sheepdog - Old English (Bobtail), Male, 4 year, 37.8 kilogram • Drug: MSK, Oral, Dose: 6 Milligram per kilogram, Frequency: 1 per day • Reactions: Malaise, Gastric ulcer, Peritonitis, Fluid in abdomen NOS, Abdominal pain… • Outcome: Euthanized

  • Report ID: DEU-USFDACVM-2025-DE-000039
  • Serious AE: Yes
  • Treated For AE: No
  • Sex: Male
  • Age: 4.00 Year
  • Weight: 37.800 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Dose: 6 Milligram per kilogram
  • Frequency: 1 per day
Reactions Reported:
Malaise Gastric ulcer Peritonitis Fluid in abdomen NOS Abdominal pain Vomiting Abnormal ultrasound finding Death Hyperthermia
Outcomes: Euthanized

Dog, Dog (other), Female, 4 year, 33.29 kilogram • Drug: MSK, Unknown • Reactions: Facial paralysis, Facial palsy • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-056006
  • Serious AE: Yes
  • Treated For AE: No
  • Sex: Female
  • Age: 4.00 Year
  • Weight: 33.290 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Facial paralysis Facial palsy
Outcomes: Outcome Unknown

Dog, Doberman Pinscher, Female, 1 year, 16 kilogram • Drug: MSK, Tablet, chewable, Oral, Dose: 0.50 tablet per dose, Frequency: 24 per hour • Reactions: Vomiting, Not drinking, Elevated creatinine, Elevated blood urea nitrogen, Abdominal pain… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-052666
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 1.00 Year
  • Weight: 16.000 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet, chewable
  • Dose: 0.50 tablet per dose
  • Frequency: 24 per hour
Reactions Reported:
Vomiting Not drinking Elevated creatinine Elevated blood urea nitrogen Abdominal pain Weight loss Unwell Leucocytosis NOS Overdose
Outcomes: Ongoing

Cat, Domestic Shorthair, Male, 6 year, 5.08 kilogram • Drug: MSK, Tablet, chewable, Oral, Dose: 28.50 Milligram per animal • Reactions: Panting, Limb non-weight bearing, Other abnormal test result NOS, Cold feeling of extremity, Death by euthanasia… • Outcome: Euthanized

  • Report ID: USA-USFDACVM-2025-US-003624
  • Serious AE: Yes
  • Treated For AE: No
  • Sex: Male
  • Age: 6.00 Year
  • Weight: 5.080 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet, chewable
  • Dose: 28.50 Milligram per animal
Reactions Reported:
Panting Limb non-weight bearing Other abnormal test result NOS Cold feeling of extremity Death by euthanasia Administration error NOS
Outcomes: Euthanized

Cat, Domestic Shorthair, Male, 8 year, 7.5 kilogram • Drug: MSK, Oral, Dose: 0.50 tablet per dose, Frequency: 1 per day • Reactions: Elevated liver enzymes NOS • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2024-US-062529
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 8.00 Year
  • Weight: 7.500 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Dose: 0.50 tablet per dose
  • Frequency: 1 per day
Reactions Reported:
Elevated liver enzymes NOS
Outcomes: Outcome Unknown

Cat, Domestic Shorthair, Male, 8 year, 7.257 kilogram • Drug: MSK, Tablet, chewable, Oral, Dose: 1 dose per 0.5 tablet, Frequency: 1 per day • Reactions: Elevated liver enzymes NOS • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2024-US-042972
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 8.00 Year
  • Weight: 7.257 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet, chewable
  • Dose: 1 dose per 0.5 tablet
  • Frequency: 1 per day
Reactions Reported:
Elevated liver enzymes NOS
Outcomes: Outcome Unknown

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Overdose Information

No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.

Storage & Handling

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