Roxee Meds Catalog

Florfenicol

Medication catalog facts with explicit FDA-approval, off-label, source-limited, and safety context.

Both Catalog complete FDA data linked Rx required Injectable Solution Multiple FDA labelers Official label facts Owner quick guide first

Start Symptom Intake Talk to a Vet / Find a Vet Near You

Veterinary professional?

Showing simplified owner view. Switch to Vet View for full technical detail.

Data freshness

Storefront facts

Catalog refreshed

May 5, 2026, 10:00 a.m.

These are the storefront facts Roxee uses on browse cards and quick facts.

FDA applications

FDA application data refreshed

May 5, 2026, 10:00 a.m.

Sponsor, product, and application records imported from Animal Drugs @ FDA.

Safety reports

No safety reports linked

No refresh timestamp yet

openFDA reaction terms and case summaries are supporting evidence, not proof of causality.

Source timing details

Storefront facts: Source Roxee | Refreshed May 5, 2026, 10:00 AM UTC
The storefront fact projection used for browse cards and quick facts.
Animal Drugs @ FDA: Source FDA | Refreshed May 5, 2026, 10:00 AM UTC
Applications/products are imported from FDA export data.
Animal Drugs @ FDA previews: Source FDA | Refreshed Feb 9, 2026, 3:05 AM UTC
Label highlights/doc links are fetched from FDA preview endpoints.
Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed May 5, 2026, 10:00 AM UTC
Package/product NDCs from FDA’s electronic listing directory (XLS).

Evidence

Reviewed / Updated / Sources

Reviewed by: Not available

Last reviewed: February 12, 2026

Updated: February 12, 2026, 10:44 PM UTC

Sources:

FDA application profile · official_label
FDA application profile · official_label
Medication usage source · fda_animal_drugs
FLORFENICOL INJECTION · official_label
openFDA case USA-USFDACVM-2025-US-068768 · adverse_reaction

Image coming soon

Florfenicol

Drug type: Generic ingredient • Branded profile • FDA branded products available

Both Injectable Solution Rx required 100% storefront ready

Species: Both

Manufacturer: Multiple FDA labelers

Medication Snapshot

Merged from the current Roxee medication system with field-level provenance, freshness, and completeness tracking.

Florfenicol

For control of respiratory disease in cattle at high risk of developing BRD associated with Mannheimia haemolytica , Pasteurella multocida , and Histophilus somni . For treatment of bovine respiratory disease (BRD) associated with Mannheimia haemolytica , Pasteurella multocida , and Haemophilus somni . For treatment of bovine interdigital phlegmon (foot rot, acute interdigital necrobacillosis, infectious pododermatitis) associated with Fusobacterium necrophorum and Bacteroides melaninogenicus . Species commonly shown: Both, Beef, excluding veal calves, Dairy, females Under 20 months of age.

Generic name

Florfenicol

Brand names

Nuflor® Nuflor®-S, Nuflor® Concentrate Solution, Aquaflor® Type A Medicated Article, Nuflor®

Manufacturer

Multiple FDA labelers

Species

Both, Beef, excluding veal calves, Dairy, females Under 20 months of age, No use class stated or implied

Dosage forms

Injectable Solution, Liquid (Solution), Medicated Feed, Type A Medicated Article

Prescription

Prescription required

Completeness

100%

Validation

Complete

Brand names

Nuflor® Nuflor®-S Nuflor® Concentrate Solution Aquaflor® Type A Medicated Article Nuflor® NuflorGOLD™ Florvio™ 2.3% Concentrate Solution Loncor® 300 FLORFENICOL INJECTION FLORCON Norfenicol® Florfeniject™ PAQFLOR™ Nuflor Florfenicol Florfeniject Loncor 300 X PAQFLOR Aquaflor Type A Medicated Article Nuflor-S Norfenicol

Dosage forms

Injectable Solution Liquid (Solution) Medicated Feed Type A Medicated Article Oral Concentrate Solution Solution Type A medicated articles to be used in the manufacture of Type C medicated feeds

Indications / Uses

Warnings / Contraindications

Federal law restricts this drug to use by or on the order of a licensed veterinarian. Feed containing florfenicol shall not be fed for more than 10 days. Following administration, fish should be reevaluated by a licensed veterinarian before initiating a further course of therapy. For catfish, a dose-related decrease in hematopoietic/lymphopoietic tissue may occur. The time required for hematopoietic/lymphopoietic tissues to regenerate was not evaluated. Not for use in animals intended for breeding purposes. The effects of florfenicol on reproductive performance have not been determined. Toxicity studies in dogs, rats, and mice have associated the use of florfenicol with testicular degeneration and atrophy. Federal law limits this drug to use under the professional supervision of a licensed veterinarian. See Sec. 558.6 of this chapter for additional requirements. The expiration date of veterinary feed directives (VFDs) for florfenicol must not exceed 6 months from the date of issuance. VFDs for florfenicol shall not be refilled. Feed containing florfenicol shall not be fed for more than 10 days. Following administration, fish should be reevaluated by a licensed veterinarian before initiating a further course of therapy. A dose-related decrease in hematopoietic/lymphopoietic tissue may occur. The time required for hematopoietic/lymphopoietic tissues to regenerate was not evaluated. Not for use in animals intended for breeding purposes. The effects of florfenicol on reproductive performance have not been determined. Toxicity studies in dogs, rats, and mice have associated the use of florfenicol with testicular degeneration and atrophy. Federal law limits this drug to use under the professional supervision of a licensed veterinarian. See Sec. 558.6 of this chapter for additional requirements. The expiration date of veterinary feed directives (VFDs) for florfenicol must not exceed 6 months from the date of issuance. VFDs for florfenicol shall not be refilled.

Federal law restricts this drug to use by or on the order of a licensed veterinarian. Feed containing florfenicol shall not be fed for more than 10 days. Following administration, fish should be reevaluated by a licensed veterinarian before initiating a further course of therapy. For catfish, a dose-related decrease in hematopoietic/lymphopoietic tissue may occur. The time required for hematopoietic/lymphopoietic tissues to regenerate was not evaluated. Not for use in animals intended for breeding purposes. The effects of florfenicol on reproductive performance have not been determined. Toxicity studies in dogs, rats, and mice have associated the use of florfenicol with testicular degeneration and atrophy. Federal law limits this drug to use under the professional supervision of a licensed veterinarian. See Sec. 558.6 of this chapter for additional requirements. The expiration date of veterinary feed directives (VFDs) for florfenicol must not exceed 6 months from the date of issuance. VFDs for florfenicol shall not be refilled. Feed containing florfenicol shall not be fed for more than 10 days. Following administration, fish should be reevaluated by a licensed veterinarian before initiating a further course of therapy. A dose-related decrease in hematopoietic/lymphopoietic tissue may occur. The time required for hematopoietic/lymphopoietic tissues to regenerate was not evaluated. Not for use in animals intended for breeding purposes. The effects of florfenicol on reproductive performance have not been determined. Toxicity studies in dogs, rats, and mice have associated the use of florfenicol with testicular degeneration and atrophy. Federal law limits this drug to use under the professional supervision of a licensed veterinarian. See Sec. 558.6 of this chapter for additional requirements. The expiration date of veterinary feed directives (VFDs) for florfenicol must not exceed 6 months from the date of issuance. VFDs for florfenicol shall not be refilled.

Side Effects

Top reported reactions (openFDA): Lack of efficacy - NOS, Vomiting, Head tilt - ear disorder, Ataxia, Ear discharge, Corneal ulcer.

FAQ

Both, Beef, excluding veal calves, Dairy, females Under 20 months of age, No use class stated or implied, Finfish, Freshwater-Reared, Salmonids, Freshwater-Reared, Catfish, Warmwater Finfish, Freshwater-Reared, Beef, Beef And Non-Lactating Dairy, Freshwater-Reared Salmonids, Freshwater-reared warmwater finfish, Freshwater-reared finfish

Yes. Roxee shows this as prescription-only.

Injectable Solution, Liquid (Solution), Medicated Feed, Type A Medicated Article

Related Conditions

Pneumonia (aspiration, bacterial, viral) Pododermatitis

Source Transparency

Verified source: https://www.roxee.ai/meds/
Verified source: https://animaldrugsatfda.fda.gov
Verified source: https://animaldrugsatfda.fda.gov/adafda/views/#/search
Verified source: https://api.fda.gov/animalandveterinary/event.json
Verified source: https://www.roxee.ai/conditions/
Verified source: https://animaldrugsatfda.fda.gov/adafda/app/search/public/document/downloadFoi/17866
Last refreshed: May 5, 2026, 10:00 a.m.
Last verified: Feb 12, 2026, 10:44 p.m.
Validation status: Complete

Add to My Pet's Meds

Choose a pet, confirm current or past, and optionally add reminder notes.

Pet Owner Quick Guide

Start here first for the safest next-step summary before the deeper medication detail.

Used for:

For control of respiratory disease in cattle at high-risk of developing BRD.

Dosing note:

Exact dosing depends on your pet's species, weight, and health status. Use your veterinarian's instructions for the exact dose and schedule.

What to watch for:

Feed containing florfenicol shall not be fed for more than 10 days
Following administration, fish should be reevaluated by a licensed veterinarian before initiating a further course of therapy
For catfish, a dose-related decrease in hematopoietic/lymphopoietic tissue may occur
The time required for hematopoietic/lymphopoietic tissues to regenerate was not evaluated
Not for use in animals intended for breeding purposes
The effects of florfenicol on reproductive performance have not been determined
Toxicity studies in dogs, rats, and mice have associated the use of florfenicol with testicular degeneration and atrophy
Federal law limits this drug to use under the professional supervision of a licensed veterinarian
See Sec
558.6 of this chapter for additional requirements
The expiration date of veterinary feed directives (VFDs) for florfenicol must not exceed 6 months from the date of issuance
VFDs for florfenicol shall not be refilled
A dose-related decrease in hematopoietic/lymphopoietic tissue may occur
Loss of appetite (1 reports)
Hind limb paresis (1 reports)
Head shake - ear disorder (1 reports)

When to call the vet:

Repeated vomiting or diarrhea.
Severe lethargy (hard to wake, very low energy).
Collapse or fainting.
Trouble breathing.
Facial swelling or hives.
Blood in vomit or stool.

Regulatory restrictions are shown in Vet View.

What to tell or ask your vet today:

Is this medicine the right fit for my pet’s current symptoms?
Which warning signs mean I should call back right away?
How should I handle missed doses or refusal to take the medicine?

Major cautions & emergency warning signs

Side effects to monitor:

Feed containing florfenicol shall not be fed for more than 10 days
Following administration, fish should be reevaluated by a licensed veterinarian before initiating a further course of therapy
For catfish, a dose-related decrease in hematopoietic/lymphopoietic tissue may occur
The time required for hematopoietic/lymphopoietic tissues to regenerate was not evaluated
Not for use in animals intended for breeding purposes

Most reported reactions:

Loss of appetite (1 reports)
Hind limb paresis (1 reports)
Head shake - ear disorder (1 reports)

Emergency warning signs:

Repeated vomiting or diarrhea.
Severe lethargy (hard to wake, very low energy).
Collapse or fainting.
Trouble breathing.

Talk to a Vet / Find a Vet Near You Start Symptom Intake

Quick Facts

Official label facts first, then secondary summaries. Marketing content is separated below.

Species: Both

Manufacturer: Multiple FDA labelers

Form: Injectable Solution, Liquid (Solution), Medicated Feed, Oral Concentrate Solution, Solution, Type A Medicated Article

Identifiers:

ANADA: 200519 ANADA: 200582 ANADA: 200588 ANADA: 200589 ANADA: 200591 ANADA: 200719 ANADA: 200760 ANADA: 200803 ANADA: 200828 ANADA: 200829 ANADA: 200848 NADA: 141063 NADA: 141206 NADA: 141246 NADA: 141264 NADA: 141265 NADA: 141299 NADA: 141437 NADA: 141440 NDC Package: 0061-1116-04

Source metadata:

https://animaldrugsatfda.fda.gov/adafda/views/#/home/previewsearch/200582 · official_label · FDA application profile
https://animaldrugsatfda.fda.gov/adafda/views/#/home/previewsearch/200803 · official_label · FDA application profile
https://animaldrugsatfda.fda.gov · fda_animal_drugs · Medication usage source

Warnings / Contraindications

High: Federal law restricts this drug to use by or on the order of a licensed veterinarian. Feed containing florfenicol shall not be fed for more than 10 days. Following administration, fish should be reevaluated by a licensed veterinarian before initiating a further course of therapy. For catfish, a dose-related decrease in hematopoietic/lymphopoietic tissue may occur. The time required for hematopoietic/lymphopoietic tissues to regenerate was not evaluated. Not for use in animals intended for breeding purposes. The effects of florfenicol on reproductive performance have not been determined. Toxicity studies in dogs, rats, and mice have associated the use of florfenicol with testicular degeneration and atrophy. Federal law limits this drug to use under the professional supervision of a licensed veterinarian. See Sec. 558.6 of this chapter for additional requirements. The expiration date of veterinary feed directives (VFDs) for florfenicol must not exceed 6 months from the date of issuance. VFDs for florfenicol shall not be refilled. Feed containing florfenicol shall not be fed for more than 10 days. Following administration, fish should be reevaluated by a licensed veterinarian before initiating a further course of therapy. A dose-related decrease in hematopoietic/lymphopoietic tissue may occur. The time required for hematopoietic/lymphopoietic tissues to regenerate was not evaluated. Not for use in animals intended for breeding purposes. The effects of florfenicol on reproductive performance have not been determined. Toxicity studies in dogs, rats, and mice have associated the use of florfenicol with testicular degeneration and atrophy. Federal law limits this drug to use under the professional supervision of a licensed veterinarian. See Sec. 558.6 of this chapter for additional requirements. The expiration date of veterinary feed directives (VFDs) for florfenicol must not exceed 6 months from the date of issuance. VFDs for florfenicol shall not be refilled.

Source metadata:

https://animaldrugsatfda.fda.gov · fda_animal_drugs · Contraindication source

Adverse Reactions

Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.

Tap or hover a reaction to see what it means in plain language.

Tracked signals

Reported cases

Serious reports

Species represented

Grouped by Body System

Digestive (3) · Loss of appetite, Decreased appetite, Bloody diarrhoea Skin & allergy (2) · Hair loss at application site, Application site swelling Neurologic (3) · Unsteady walking (ataxia), Head tilt - neurological disorder, Circling - neurological disorder Other (24) · Hind limb paresis, High blood pressure, Hiding

Most Reported Reactions

Body system	Cases	Species	Serious cases
Digestive	1	Cat	1
Other	1	Dog	1
Other	1	Cat	1
Other	1	Dog	1
Other	1	Cat	1
Other	1	Dog	1
Other	1	Cat	1
Other	1	Cat	1

Species coverage: Cat (20) Dog (12)

View detailed reaction table

Body system	Species	Seriousness	Frequency	Reports
Neurologic	Cat	Non-serious	-	1
Digestive	Cat	Serious	-	1
Other	Dog	Serious	-	1
Other	Dog	Non-serious	-	1
Other	Cat	Non-serious	-	1
Neurologic	Cat	Non-serious	-	1
Other	Dog	Non-serious	-	1
Other	Cat	Serious	-	1
Skin & allergy	Dog	Non-serious	-	1
Other	Cat	Non-serious	-	1
Other	Cat	Non-serious	-	1
Other	Dog	Serious	-	1
Other	Cat	Serious	-	1
Other	Dog	Serious	-	1
Other	Dog	Non-serious	-	1
Other	Cat	Serious	-	1
Other	Dog	Non-serious	-	1
Other	Dog	Non-serious	-	1
Other	Cat	Serious	-	1
Digestive	Cat	Non-serious	-	1
Other	Dog	Serious	-	1
Other	Cat	Serious	-	1
Other	Dog	Serious	-	1
Other	Cat	Non-serious	-	1
Neurologic	Cat	Non-serious	-	1
Digestive	Dog	Serious	-	1
Other	Cat	Serious	-	1
Other	Cat	Non-serious	-	1
Skin & allergy	Cat	Serious	-	1
Other	Cat	Serious	-	1
Other	Cat	Non-serious	-	1
Other	Cat	Serious	-	1

Source metadata:

https://api.fda.gov/animalandveterinary/event.json · adverse_reaction · openFDA case USA-USFDACVM-2025-US-068768

Documents

Owner handouts and official technical documents open on-page first, with the original source still one click away.

Owner handouts

No owner handouts linked yet.

Official label / PI

SPL

Open original

Loncor® 300

SPL · SPL

Open original

FDA Structured Product Label

Loncor® 300

Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.

Sponsor: Zoetis Inc.
ANADA: 200-582
Status: RX
Form: Injectable Solution
Route: Intramuscular, Subcutaneous
Species: Beef And Non-Lactating Dairy

Composition / specifications

300 mg/mL

Beef and non-lactating dairy cattle

Indication

For control of respiratory disease in cattle at high-risk of developing BRD.

Dosage

Administer by a single subcutaneous injection to cattle at a dose rate of 40 mg/kg body weight (6 mL/100 lbs). Do not administer more than 10 mL at each site. The injection should be given only in the neck.

Indication

For treatment of bovine respiratory disease (BRD) and bovine interdigital phlegmon (foot rot).

Dosage

Administer by intramuscular injection to cattle at a dose rate of 20 mg/kg body weight (3 mL/100 lbs). A second dose should be administered 48 hours later. Alternatively, it can be administered by a single subcutaneous (SC) injection to cattle at a dose rate of 40 mg/kg body weight (6 mL/100 lbs). Do not administer more than 10 mL at each site. The injection should be given only in the neck. NOTE: Intramuscular injection may result in local tissue reaction which persists beyond 28 days. This may result in trim loss of edible tissue at slaughter. Tissue reaction at injection sites other than the neck is likely to be more severe.

PAQFLOR™

SPL · SPL

Open original

FDA Structured Product Label

PAQFLOR™

Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.

Sponsor: Phibro Animal Health Corp.
ANADA: 200-803
Status: VFD
Form: Type A medicated articles to be used in the manufacture of Type C medicated feeds
Route: Oral
Species: Catfish • Freshwater-Reared Salmonids • Freshwater-reared warmwater finfish • Freshwater-reared finfish

Composition / specifications

500 g/kg (227.27 g/lb) florfenicol

Freshwater-reared salmonids

Indication

For the control of mortality due to furunculosis associated with Aeromonas salmonicida. For the control of mortality due to coldwater disease associated with Flavobacterium psychrophilum.

Dosage

10-15 mg/kg body weight/day for 10 consecutive days

Freshwater-reared finfish

Indication

For the control of mortality due to columnaris disease associated with Flavobacterium columnare.

Dosage

10-15 mg/kg body weight/day for 10 consecutive days

Catfish

Indication

For the control of mortality due to enteric septicemia of catfish associated with Edwardsiella ictaluri.

Dosage

10-15 mg/kg body weight/day for 10 consecutive days

Freshwater-reared warmwater finfish

Indication

For the control of mortality due to streptococcal septicemia associated with Streptococcus iniae.

Dosage

15 mg/kg body weight/day for 10 consecutive days

FLORFENICOL INJECTION

SPL · SPL

Open original

FDA Structured Product Label

FLORFENICOL INJECTION

Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.

Sponsor: Sparhawk Laboratories, Inc.
ANADA: 200-588
Status: RX
Form: Injectable Solution
Route: Subcutaneous, Intramuscular
Species: Beef And Non-Lactating Dairy

Composition / specifications

300 mg/mL

Beef and non-lactating dairy cattle

Indication

For treatment of bovine respiratory disease (BRD) associated with Mannheimia haemolytica, Pasteurella multocida, and Histophilus somni.

For the treatment of bovine interdigital phlegmon (foot rot, acute interdigital necrobacillosis, infectious pododermatitis) associated with Fusobacterium necrophorum and Bacteroides melaninogenicus.

Dosage

Indication

For the control of respiratory disease in cattle at high risk of developing BRD associated with Mannheimia haemolytica, Pasteurella multocida, and Histophilus somni.

Dosage

Nuflor®

SPL · SPL

Open original

FDA Structured Product Label

Nuflor® Nuflor®-S

Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.

Sponsor: Intervet, Inc.
NADA: 141-063
Status: RX
Form: Injectable Solution
Route: Intramuscular, Subcutaneous
Species: Beef, excluding veal calves • Dairy, females Under 20 months of age

Composition / specifications

Each milliliter of sterile solution contains 300 milligrams of florfenicol.

Cattle (Beef and Non-Lactating Dairy)

Indication

For control of respiratory disease in cattle at high risk of developing BRD associated with Mannheimia haemolytica, Pasteurella multocida, and Histophilus somni.

Dosage

Administer by a single subcutaneous injection to cattle at a dose rate of 40 mg/kg body weight. Do not administer more than 10 mL at each site. The injection should be given only in the neck.

Indication

For treatment of bovine respiratory disease (BRD) associated with Mannheimia haemolytica, Pasteurella multocida, and Haemophilus somni.

Dosage

Administer by intramuscular injection to cattle at a dose rate of 20 mg/kg body weight. A second dose should be administered 48 hours later. Alternatively, administer by a single subcutaneous injection to cattle at a dose rate of 40 mg/kg body weight. Do not administer more than 10 mL at each site. The injection should be given only in the neck.

Indication

For treatment of bovine interdigital phlegmon (foot rot, acute interdigital necrobacillosis, infectious pododermatitis) associated with Fusobacterium necrophorum and Bacteroides melaninogenicus.

Dosage

Nuflor®-S

SPL · SPL

Open original

FDA Structured Product Label

Nuflor® Nuflor®-S

Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.

Sponsor: Intervet, Inc.
NADA: 141-063
Status: RX
Form: Injectable Solution
Route: Intramuscular, Subcutaneous
Species: Beef, excluding veal calves • Dairy, females Under 20 months of age

Composition / specifications

Each milliliter of sterile solution contains 300 milligrams of florfenicol.

Cattle (Beef and Non-Lactating Dairy)

Indication

For control of respiratory disease in cattle at high risk of developing BRD associated with Mannheimia haemolytica, Pasteurella multocida, and Histophilus somni.

Dosage

Administer by a single subcutaneous injection to cattle at a dose rate of 40 mg/kg body weight. Do not administer more than 10 mL at each site. The injection should be given only in the neck.

Indication

For treatment of bovine respiratory disease (BRD) associated with Mannheimia haemolytica, Pasteurella multocida, and Haemophilus somni.

Dosage

Indication

For treatment of bovine interdigital phlegmon (foot rot, acute interdigital necrobacillosis, infectious pododermatitis) associated with Fusobacterium necrophorum and Bacteroides melaninogenicus.

Dosage

Florfeniject™

SPL · SPL

Open original

FDA Structured Product Label

Florfeniject™

Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.

Sponsor: Cronus Pharma Specialities India Private Ltd.
ANADA: 200-760
Status: RX
Form: Injectable Solution
Route: Subcutaneous, Intramuscular
Species: Beef And Non-Lactating Dairy

Composition / specifications

300 mg/mL

Beef and non-lactating dairy cattle

Indication

For treatment of bovine respiratory disease (BRD) associated with Mannheimia haemolytica, Pasteurella multocida, and Histophilus somni, and for the treatment of bovine interdigital phlegmon (foot rot, acute interdigital necrobacillosis, infectious pododermatitis) associated with Fusobacterium necrophorum and Bacteroides melaninogenicus. Also, it is indicated for the control of respiratory disease in cattle at high risk of developing BRD associated with Mannheimia haemolytica, Pasteurella multocida, and Histophilus somni.

Aquaflor® Type A Medicated Article

SPL · SPL

Open original

FDA Structured Product Label

Aquaflor® Type A Medicated Article

Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.

Sponsor: Intervet, Inc.
NADA: 141-246
Status: VFD
Form: Medicated Feed
Route: Oral
Species: Finfish, Freshwater-Reared • Salmonids, Freshwater-Reared • Catfish • Warmwater Finfish, Freshwater-Reared

Composition / specifications

Type A medicated article containing 500 grams florfenicol per kilogram.

Freshwater-reared warmwater finfish

Indication

For the control of mortality due to streptococcal septicemia associated with Streptococcus iniae

Dosage

15 mg florfenicol per kg of fish

Limitations

Feed containing florfenicol shall not be fed for more than 10 days. Following administration, fish should be reevaluated by a licensed veterinarian before initiating a further course of therapy. For catfish, a dose-related decrease in hematopoietic/lymphopoietic tissue may occur. The time required for hematopoietic/lymphopoietic tissues to regenerate was not evaluated. Not for use in animals intended for breeding purposes. The effects of florfenicol on reproductive performance have not been determined. Toxicity studies in dogs, rats, and mice have associated the use of florfenicol with testicular degeneration and atrophy. Federal law limits this drug to use under the professional supervision of a licensed veterinarian. See Sec. 558.6 of this chapter for additional requirements. The expiration date of veterinary feed directives (VFDs) for florfenicol must not exceed 6 months from the date of issuance. VFDs for florfenicol shall not be refilled.

Catfish

Indication

For the control of mortality due to enteric septicemia of catfish associated with Edwardsiella ictaluri.

Dosage

10 to 15 milligrams (mg) florfenicol per kilogram (kg) of fish

Limitations

Feed containing florfenicol shall not be fed for more than 10 days. Following administration, fish should be reevaluated by a licensed veterinarian before initiating a further course of therapy. A dose-related decrease in hematopoietic/lymphopoietic tissue may occur. The time required for hematopoietic/lymphopoietic tissues to regenerate was not evaluated. Not for use in animals intended for breeding purposes. The effects of florfenicol on reproductive performance have not been determined. Toxicity studies in dogs, rats, and mice have associated the use of florfenicol with testicular degeneration and atrophy. Federal law limits this drug to use under the professional supervision of a licensed veterinarian. See Sec. 558.6 of this chapter for additional requirements. The expiration date of veterinary feed directives (VFDs) for florfenicol must not exceed 6 months from the date of issuance. VFDs for florfenicol shall not be refilled.

Finfish

Indication

For the control of mortality due to columnaris disease associated with Flavobacterium columnare.

Dosage

10 to 15 mg florfenicol per kg of fish

Limitations

Salmonids

Indication

For the control of mortality due to coldwater disease associated with Flavobacterium psychrophilum and furunculosis associated with Aeromonas salmonicida.

Dosage

10 to 15 mg florfenicol per kg of fish

Limitations

Following administration, fish should be reevaluated by a licensed veterinarian before initiating a further course of therapy. Not for use in animals intended for breeding purposes. The effects of florfenicol on reproductive performance have not been determined. Toxicity studies in dogs, rats, and mice have associated the use of florfenicol with testicular degeneration and atrophy. Federal law limits this drug to use under the professional supervision of a licensed veterinarian. See Sec. 558.6 of this chapter for additional requirements. The expiration date of veterinary feed directives (VFDs) for florfenicol must not exceed 6 months from the date of issuance. VFDs for florfenicol shall not be refilled.

Norfenicol®

SPL · SPL

Open original

FDA Structured Product Label

Norfenicol®

Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.

Sponsor: Norbrook Laboratories, Ltd.
ANADA: 200-591
Status: RX
Form: Solution
Route: Intramuscular, Subcutaneous
Species: Beef And Non-Lactating Dairy

Label highlights

Indication

For the treatment of bovine respiratory disease (BRD) associated with Mannheimia haemolytica, Pasteurella multocida, and Histophilus somni, and for the treatment of bovine interdigital phlegmon (foot rot, acute interdigital necrobacillosis, infectious pododermatitis) associated with Fusobacterium necrophorum and Bacteriodes melaninogenicus. Also, it is indicated for the control of respiratory disease in cattle at high risk of developing BRD associated with Mannheimia haemolytica, Pasteurella multocida, and Histophilus somni.</

Dosage

For treatment of bovine respiratory disease (BRD) and bovine interdigital phlegmon (foot rot):

Norfenicol® Injectable Solution should be administered by intramuscular injection to cattle at a dose rate of 20 mg/kg body weight (3 mL/100 lbs). A second dose should be administered 48 hours later. Alternatively, Norfenicol® Injectable Solution can be administered by a single subcutaneous (SC) injection to cattle at a dose rate of 40 mg/kg body weight (6 mL/100 lbs). Do not administer more than 10 mL at each site. The injection should be given only in the neck. NOTE: Intramuscular injection may result in local tissue reaction which persists beyond 28 days. This may result in trim loss of edible tissue at slaughter. Tissue reaction at injection sites other than the neck is likely to be more severe.

For control of respiratory disease in cattle at high-risk of developing BRD:

Norfenicol® Injectable Solution should be administered by a single subcutaneous injection to cattle at a dose rate of 40 mg/kg body weight (6 mL/100 lbs). Do not administer more than 10 mL at each site. The injection should be given only in the neck.

Limitations

This drug product is not approved for use in female dairy cattle 20 months of age or older, including dry dairy cows. Use in these cattle may cause drug residues in milk and/or in calves born to these cows. A withdrawal period has not been established in preruminating calves

Nuflor®

SPL · SPL

Open original

FDA Structured Product Label

Nuflor®

Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.

Sponsor: Intervet, Inc.
NADA: 141-264
Status: VFD
Form: Type A Medicated Article
Route: Oral
Species: No use class stated or implied

Composition / specifications

Type A medicated article containing florfenicol at 18.2 g/lb (40 g/kg).

Swine

Indication

For the control of swine respiratory disease (SRD) associated with Actinobacillus pleuropneumoniae, Pasteurella multocida, Streptococcus suis, and Bordetella bronchiseptica in groups of swine in buildings experiencing an outbreak of SRD.

Dosage

Feed 182 grams per ton of feed (200 parts per million) continuously as the sole ration for 5 days.

Limitations

The safety of florfenicol on swine reproductive performance, pregnancy, and lactation has not been determined. Feed containing florfenicol shall not be fed to pigs for more than 5 days. The expiration date of veterinary feed directives (VFDs) for florfenicol medicated feeds for swine must not exceed 90 days from the date of issuance. VFDs for florfenicol shall not be refilled.

FLORCON

SPL · SPL

Open original

FDA Structured Product Label

FLORCON

Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.

Sponsor: Med-Pharmex, Inc.
ANADA: 200-589
Status: RX
Form: Liquid (Solution)
Route: Oral
Species: No use class stated or implied

Composition / specifications

23 mg florfenicol/ml

Swine

Indication

For the treatment of swine respiratory disease associated with Actinobacillus pleuropneumoniae, Pasteurella multocida, Salmonella choleraesuis, and Streptococcus suis in swine.

Dosage

Dilute to 400 mg/gallon of water (100 ppm) and administer as the only source of drinking water for five (5) consecutive days.

Limitations

Not for use in swine intended for breeding. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Florvio™ 2.3% Concentrate Solution

SPL · SPL

Open original

FDA Structured Product Label

Florvio™ 2.3% Concentrate Solution

Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.

Sponsor: Elanco US Inc.
ANADA: 200-519
Status: RX
Form: Oral Concentrate Solution
Route: Oral
Species: No use class stated or implied

Composition / specifications

23 mg florfenicol/mL

Label highlights

Indication

For the treatment of swine respiratory disease associated with Actinobacillus pleuropneumoniae, Pasteurella multocida, Salmonella choleraesuis, and Streptococcus suis in swine.

Dosage

400 mg per gallon of water (100 parts per million (ppm)) provided in the drinking water for 5 consecutive days.

Limitations

Federal law restricts this drug to use by or on the order of a licensed veterinarian

Nuflor® Concentrate Solution

SPL · SPL

Open original

FDA Structured Product Label

Nuflor® Concentrate Solution

Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.

Sponsor: Intervet, Inc.
NADA: 141-206
Status: RX
Form: Liquid (Solution)
Route: Oral
Species: No use class stated or implied

Composition / specifications

Each milliliter contains 23 milligrams florfenicol.

Swine

Indication

For the treatment of swine respiratory disease (SRD) associated with Actinobacillus pleuropneumoniae, Pasteurella multocida, Salmonella choleraesuis and Streptococcus suis.

Dosage

Administer in drinking water ad libitum at 400 mg per gallon (100 parts per million) for 5 consecutive days.

Limitations

Federal law restricts this drug to use by or on the order of a licensed veterinarian.

NuflorGOLD™

SPL · SPL

Open original

FDA Structured Product Label

NuflorGOLD™

Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.

Sponsor: Intervet, Inc.
NADA: 141-265
Status: RX
Form: Liquid (Solution)
Route: Subcutaneous
Species: Beef • Dairy, females Under 20 months of age

Composition / specifications

Each mL of solution contains 300 mg florfenicol in the inactive vehicles 2-pyrrolidone and triacetin.

Cattle (Beef and Non-Lactating Dairy)

Source metadata:

https://animaldrugsatfda.fda.gov/adafda/app/search/public/document/downloadFoi/1257 · document · FOI
https://animaldrugsatfda.fda.gov/adafda/app/search/public/spl/file/2273/Loncor%C2%AE%20300 · document · SPL
https://animaldrugsatfda.fda.gov/adafda/app/search/public/document/downloadFoi/16248 · document · FOI
https://animaldrugsatfda.fda.gov/adafda/app/search/public/spl/file/16597/PAQFLOR%E2%84%A2 · document · SPL
https://animaldrugsatfda.fda.gov/adafda/app/search/public/document/downloadFoi/11483 · document · FOI
https://animaldrugsatfda.fda.gov/adafda/app/search/public/spl/file/11586/FLORFENICOL%20INJECTION · document · SPL
https://animaldrugsatfda.fda.gov/adafda/app/search/public/document/downloadFoi/11195 · document · FOI
https://animaldrugsatfda.fda.gov/adafda/app/search/public/document/downloadFoi/3553 · document · FOI
https://animaldrugsatfda.fda.gov/adafda/app/search/public/document/downloadFoi/598 · document · FOI
https://animaldrugsatfda.fda.gov/adafda/app/search/public/document/downloadFoi/597 · document · FOI

Veterinary reference (advanced)

Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.

At a Glance

Quick facts and links to official labeling and safety signals.

Data freshness

Storefront facts: Source Roxee | Refreshed May 5, 2026, 10:00 AM UTC
The storefront fact projection used for browse cards and quick facts.
Animal Drugs @ FDA: Source FDA | Refreshed May 5, 2026, 10:00 AM UTC
Applications/products are imported from FDA export data.
Animal Drugs @ FDA previews: Source FDA | Refreshed Feb 9, 2026, 3:05 AM UTC
Label highlights/doc links are fetched from FDA preview endpoints.
Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed May 5, 2026, 10:00 AM UTC
Package/product NDCs from FDA’s electronic listing directory (XLS).

Official (FDA)

Identity: Generic ingredient • FDA branded products available

Official FDA brands: Aquaflor Type A Medicated Article FLORCON FLORFENICOL Florfenicol Florfeniject Loncor 300 Norfenicol Nuflor Nuflor-S PAQFLOR X

Manufacturer mapping: Multiple FDA labelers

Catalog species: Both • FDA-labeled species: Beef, Beef And Non-Lactating Dairy, Catfish, Dairy, Finfish, Freshwater-Reared Salmonids, Freshwater-reared finfish, Freshwater-reared warmwater finfish, No use class stated or implied, Salmonids, Warmwater Finfish

Rx/OTC: RX, VFD

Form/route: Injectable Solution, Liquid (Solution), Medicated Feed, Oral Concentrate Solution, Solution, Type A Medicated Article, Type A medicated articles to be used in the manufacture of Type C medicated feeds • Intramuscular, Oral, Subcutaneous

Applications: ANADA 200-582 • ANADA 200-803 • ANADA 200-588 • NADA 141-063 • ANADA 200-760 • NADA 141-246 • ANADA 200-591 • NADA 141-264 • ANADA 200-589 • ANADA 200-519 • NADA 141-206 • NADA 141-265

NDC: Packages 0061-1116-04 0061-1116-05 0061-1116-06 0061-1355-01 0061-5581-02 17033-425-22 • Products 0061 17033 54771 55529 58005 62157

Documents: 36 (FOI: 24) • SPL: 13 • Label highlights • Official documents

Safety (openFDA)

Top reactions: Dog 0 • Cat 0 • View

Case summaries: 0

openFDA reports are unverified and do not prove causation.

Explore

Related conditions: Pneumonia (aspiration, bacterial, viral) Pododermatitis

Linked using: Fda_Label (0.95), Fda_Label (0.95)

Diagnosis Codes

ICD10_CM: H60.90

Otitis externa, unspecified ear

Counseling and Monitoring Highlights

Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.

Owner-facing counseling points

Federal law restricts this drug to use by or on the order of a licensed veterinarian. Feed containing florfenicol shall not be fed for more than 10 days. Following administration, fish should be reevaluated by a licensed veterinarian before initiating a further course of therapy. For catfish, a dose-related decrease in hematopoietic/lymphopoietic tissue may occur. The time required for hematopoietic/lymphopoietic tissues to regenerate was not evaluated. Not for use in animals intended for breeding purposes. The effects of florfenicol on reproductive performance have not been determined. Toxicity studies in dogs, rats, and mice have associated the use of florfenicol with testicular degeneration and atrophy. Federal law limits this drug to use under the professional supervision of a licensed veterinarian. See Sec. 558.6 of this chapter for additional requirements. The expiration date of veterinary feed directives (VFDs) for florfenicol must not exceed 6 months from the date of issuance. VFDs for florfenicol shall not be refilled. Feed containing florfenicol shall not be fed for more than 10 days. Following administration, fish should be reevaluated by a licensed veterinarian before initiating a further course of therapy. A dose-related decrease in hematopoietic/lymphopoietic tissue may occur. The time required for hematopoietic/lymphopoietic tissues to regenerate was not evaluated. Not for use in animals intended for breeding purposes. The effects of florfenicol on reproductive performance have not been determined. Toxicity studies in dogs, rats, and mice have associated the use of florfenicol with testicular degeneration and atrophy. Federal law limits this drug to use under the professional supervision of a licensed veterinarian. See Sec. 558.6 of this chapter for additional requirements. The expiration date of veterinary feed directives (VFDs) for florfenicol must not exceed 6 months from the date of issuance. VFDs for florfenicol shall not be refilled. (Contraindication, High)

Top reaction signals

Loss of appetite (1) Hind limb paresis (1) Head shake - ear disorder (1) Eosinophilia (1) Eosinopenia (1) Enamel disorder (1) Elevated blood urea nitrogen (1) Dehydration (1)

Identifiers & Packages

Normalized identifiers (NDC/NADA/ANADA) and package metadata from regulator listings.

Identifiers

Package NDC	Product NDC	Status
0061-1116-04	0061	-
0061-1116-05	0061	-
0061-1116-06	0061	-
0061-1355-01	0061	-
0061-4305-01	0061	-
0061-4305-02	0061	-
0061-4305-03	0061	-
0061-5581-02	0061	-
17030-001-10	17030	-
17033-283-02	17033	-
17033-283-20	17033	-
17033-425-22	17033	-
51072-122-00	51072	-
51072-122-01	51072	-
51072-122-02	51072	-
54771-7318-1	54771	-
54771-7318-2	54771	-
55529-155-02	55529	-
55529-155-04	55529	-
55529-155-05	55529	-

Enriched Documents

Documents are tiered by source trust: Official, Clinical, Manufacturer, Marketing.

Florfenicol SPL • Structured Product Label • Official
FDA Structured Product Label from the electronic animal drug product listing directory.
FLORFENICOL SPL • Structured Product Label • Official
FDA Structured Product Label from the electronic animal drug product listing directory.
Norfenicol SPL • Structured Product Label • Official
FDA Structured Product Label from the electronic animal drug product listing directory.
Florfeniject SPL • Structured Product Label • Official
FDA Structured Product Label from the electronic animal drug product listing directory.
Nuflor SPL • Structured Product Label • Official
FDA Structured Product Label from the electronic animal drug product listing directory.
Nuflor-S SPL • Structured Product Label • Official
FDA Structured Product Label from the electronic animal drug product listing directory.
Florfenicol SPL • Structured Product Label • Official
FDA Structured Product Label from the electronic animal drug product listing directory.
Loncor 300 SPL • Structured Product Label • Official
FDA Structured Product Label from the electronic animal drug product listing directory.
FLORCON SPL • Structured Product Label • Official
FDA Structured Product Label from the electronic animal drug product listing directory.
Aquaflor Type A Medicated Article SPL • Structured Product Label • Official
FDA Structured Product Label from the electronic animal drug product listing directory.
PAQFLOR SPL • Structured Product Label • Official
FDA Structured Product Label from the electronic animal drug product listing directory.
Florfenicol SPL • Structured Product Label • Official
FDA Structured Product Label from the electronic animal drug product listing directory.
X SPL • Structured Product Label • Official
FDA Structured Product Label from the electronic animal drug product listing directory.
FLORFENICOL SPL • Structured Product Label • Official
FDA Structured Product Label from the electronic animal drug product listing directory.
FOI Summary oA 200-848 Approved April 8, 2026.pdf • FOI summary • Official • April 30, 2026
FDA FOI summary for application 200848
FOI Summary oA 200-828 Approved January 9, 2026.pdf • FOI summary • Official • Feb. 3, 2026
FDA FOI summary for application 200828
FOI Summary oA 200-829 Approved December 22, 2025.pdf • FOI summary • Official • Jan. 5, 2026
FDA FOI summary for application 200829
UCM457225.pdf • FOI summary • Official • Dec. 22, 2025
FDA FOI summary for application 200582
FOI Summary oA 200-803 Approved November 14, 2024.pdf • FOI summary • Official • Dec. 2, 2024
FDA FOI summary for application 200803
UCM203309.pdf • FOI summary • Official • Aug. 6, 2024
FDA FOI summary for application 141299
UCM231147.pdf • FOI summary • Official • Aug. 6, 2024
FDA FOI summary for application 141299
A-200588-Q-0018-OT-AA_foi.pdf • FOI summary • Official • July 10, 2024
FDA FOI summary for application 200588
FOI Summary N 141-063 Orig Approved May 31 1996.pdf • FOI summary • Official • April 30, 2024
FDA FOI summary for application 141063
N141063_Supp_4_2_1998.pdf • FOI summary • Official • April 30, 2024
FDA FOI summary for application 141063
N141063 Supp_6_4_1998_.pdf • FOI summary • Official • April 30, 2024
FDA FOI summary for application 141063
ucm116741.pdf • FOI summary • Official • April 30, 2024
FDA FOI summary for application 141063
ucm116742.pdf • FOI summary • Official • April 30, 2024
FDA FOI summary for application 141063
ucm116745.pdf • FOI summary • Official • April 30, 2024
FDA FOI summary for application 141063
Corrected FOI Summary N 141-063 for cattle Approved May 25, 2018.pdf • FOI summary • Official • April 30, 2024
FDA FOI summary for application 141063
N-141063-Q-0202-OT-AA_foi_2.pdf • FOI summary • Official • April 30, 2024
FDA FOI summary for application 141063
FOI Summary oA 200-760 Approved December 21, 2023.pdf • FOI summary • Official • Jan. 2, 2024
FDA FOI summary for application 200760
FOI Summary oA 200-719 Approved September 28, 2022.pdf • FOI summary • Official • Oct. 3, 2022
FDA FOI summary for application 200719
ucm051491.pdf • FOI summary • Official • Oct. 27, 2021
FDA FOI summary for application 141246
ucm051490.pdf • FOI summary • Official • Oct. 27, 2021
FDA FOI summary for application 141246
ucm051489.pdf • FOI summary • Official • Oct. 27, 2021
FDA FOI summary for application 141246
UCM299146.pdf • FOI summary • Official • Oct. 27, 2021
FDA FOI summary for application 141246
UCM396884.pdf • FOI summary • Official • Oct. 27, 2021
FDA FOI summary for application 141246
UCM465253.pdf • FOI summary • Official • Aug. 3, 2021
FDA FOI summary for application 141440
UCM436650.pdf • FOI summary • Official • Aug. 11, 2020
FDA FOI summary for application 141437
UCM457384.pdf • FOI summary • Official • March 17, 2019
FDA FOI summary for application 200591

Data Sources & Change Log

Every non-trivial field is expected to include provenance and update timestamps.

Official 83 Clinical 2 Manufacturer 0 Marketing 0

Current Field Facts

side_effects: Top reported reactions (openFDA): Lack of efficacy - NOS, Vomiting, Head tilt - ear disorder, Ataxia, Ear discharge, Corneal ulcer. (Clinical, 2026-05-02)
side_effects: Top reported reactions (openFDA): Lack of efficacy - NOS, Vomiting, Head tilt - ear disorder, Ataxia, Ear discharge, Corneal ulcer. (Clinical, 2026-04-11)
contraindications: Federal law restricts this drug to use by or on the order of a licensed veterinarian. Feed containing florfenicol shall not be fed for more than 10 days. Follo… (Official, 2026-05-02)
contraindications: Federal law restricts this drug to use by or on the order of a licensed veterinarian. Feed containing florfenicol shall not be fed for more than 10 days. Follo… (Official, 2026-04-30)
contraindications: Federal law restricts this drug to use by or on the order of a licensed veterinarian. Feed containing florfenicol shall not be fed for more than 10 days. Follo… (Official, 2026-04-11)
contraindications: Federal law restricts this drug to use by or on the order of a licensed veterinarian. Feed containing florfenicol shall not be fed for more than 10 days. Follo… (Official, 2026-02-12)
indications: For the control of mortality in catfish due to enteric septicemia of catfish associated with Edwardsiella ictaluri. For the control of swine respiratory diseas… (Official, 2026-05-05)
indications: For the control of mortality in catfish due to enteric septicemia of catfish associated with Edwardsiella ictaluri. For the control of swine respiratory diseas… (Official, 2026-05-03)
indications: For the control of mortality in catfish due to enteric septicemia of catfish associated with Edwardsiella ictaluri. For the control of swine respiratory diseas… (Official, 2026-05-02)
indications: For the control of mortality in catfish due to enteric septicemia of catfish associated with Edwardsiella ictaluri. For the control of swine respiratory diseas… (Official, 2026-04-29)
indications: For the control of mortality in catfish due to enteric septicemia of catfish associated with Edwardsiella ictaluri. For the control of swine respiratory diseas… (Official, 2026-04-28)
indications: For the control of mortality in catfish due to enteric septicemia of catfish associated with Edwardsiella ictaluri. For the control of swine respiratory diseas… (Official, 2026-04-27)
indications: For the control of mortality in catfish due to enteric septicemia of catfish associated with Edwardsiella ictaluri. For the control of swine respiratory diseas… (Official, 2026-04-26)
indications: For the control of mortality in catfish due to enteric septicemia of catfish associated with Edwardsiella ictaluri. For the control of swine respiratory diseas… (Official, 2026-04-25)
indications: For the control of mortality in catfish due to enteric septicemia of catfish associated with Edwardsiella ictaluri. For the control of swine respiratory diseas… (Official, 2026-04-22)
manufacturer_name: Multiple FDA labelers (Official, 2026-05-05)
manufacturer_name: Multiple FDA labelers (Official, 2026-05-03)
manufacturer_name: Multiple FDA labelers (Official, 2026-05-02)
manufacturer_name: Multiple FDA labelers (Official, 2026-04-29)
manufacturer_name: Multiple FDA labelers (Official, 2026-04-28)

Recent Revisions

side_effects updated 2026-05-02 10:05 by etl_backfill • Backfilled from existing medication fields
contraindications updated 2026-05-02 10:05 by etl_backfill • Backfilled from existing medication fields
usage updated 2026-05-02 10:05 by etl_backfill • Backfilled from existing medication fields
side_effects updated 2026-04-30 10:09 by etl_backfill • Backfilled from existing medication fields
contraindications updated 2026-04-30 10:09 by etl_backfill • Backfilled from existing medication fields
usage updated 2026-04-30 10:09 by etl_backfill • Backfilled from existing medication fields
side_effects updated 2026-04-11 10:05 by etl_backfill • Backfilled from existing medication fields
contraindications updated 2026-04-11 10:05 by etl_backfill • Backfilled from existing medication fields
usage updated 2026-04-11 10:05 by etl_backfill • Backfilled from existing medication fields
side_effects updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields
contraindications updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields
usage updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields

FDA Products & Applications (Animal Drugs @ FDA)

Official sponsor/proprietary-name/application-status records linked by active ingredient.

Product	Sponsor	Application	Status	Published
Loncor® 300 RX Florfenicol Injectable Solution • Intramuscular, Subcutaneous Label highlights Official documents	Zoetis Inc.	ANADA 200-582	Approved	Dec 22, 2025
PAQFLOR™ VFD Florfenicol Type A medicated articles to be used in the manufacture of Type C medicated feeds • Oral Label highlights Official documents	Phibro Animal Health Corp.	ANADA 200-803	Approved	Dec 2, 2024
FLORFENICOL INJECTION RX Florfenicol Injectable Solution • Subcutaneous, Intramuscular Label highlights Official documents	Sparhawk Laboratories, Inc.	ANADA 200-588	Approved	Jul 10, 2024
Nuflor® Nuflor®-S RX Florfenicol Injectable Solution • Intramuscular, Subcutaneous Label highlights Official documents	Intervet, Inc.	NADA 141-063	Approved	Apr 30, 2024
Florfeniject™ RX Florfenicol Injectable Solution • Subcutaneous, Intramuscular Label highlights Official documents	Cronus Pharma Specialities India Private Ltd.	ANADA 200-760	Approved	Jan 2, 2024
Aquaflor® Type A Medicated Article VFD Florfenicol Medicated Feed • Oral Label highlights Official documents	Intervet, Inc.	NADA 141-246	Approved	Oct 27, 2021
Norfenicol® RX Florfenicol Solution • Intramuscular, Subcutaneous Label highlights Official documents	Norbrook Laboratories, Ltd.	ANADA 200-591	Approved	Mar 17, 2019
Nuflor® VFD Florfenicol Type A Medicated Article • Oral Label highlights Official documents	Intervet, Inc.	NADA 141-264	Approved	Nov 9, 2018
FLORCON RX Florfenicol Liquid (Solution) • Oral Label highlights Official documents	Med-Pharmex, Inc.	ANADA 200-589	Approved	Jan 12, 2017
Florvio™ 2.3% Concentrate Solution RX Florfenicol Oral Concentrate Solution • Oral Label highlights Official documents	Elanco US Inc.	ANADA 200-519	Approved	Jun 1, 2016
Nuflor® Concentrate Solution RX Florfenicol Liquid (Solution) • Oral Label highlights Official documents	Intervet, Inc.	NADA 141-206	Approved	Jun 1, 2016
NuflorGOLD™ RX Florfenicol Liquid (Solution) • Subcutaneous Label highlights Official documents	Intervet, Inc.	NADA 141-265	Approved	Jun 1, 2016

Data source: FDA Animal Drugs @ FDA (public search export).

What It's For (FDA Label Highlights)

Extracted from FDA Animal Drugs @ FDA product labeling. Always confirm details with your veterinarian.

Species: Beef And Non-Lactating Dairy

Composition / specifications

300 mg/mL

Beef and non-lactating dairy cattle

Indication

For control of respiratory disease in cattle at high-risk of developing BRD.

Dosage

Limitations

Indication

For treatment of bovine respiratory disease (BRD) and bovine interdigital phlegmon (foot rot).

Dosage

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Catfish • Freshwater-Reared Salmonids • Freshwater-reared warmwater finfish • Freshwater-reared finfish

Composition / specifications

500 g/kg (227.27 g/lb) florfenicol

Freshwater-reared salmonids

Indication

For the control of mortality due to furunculosis associated with Aeromonas salmonicida. For the control of mortality due to coldwater disease associated with Flavobacterium psychrophilum.

Dosage

10-15 mg/kg body weight/day for 10 consecutive days

Limitations

Freshwater-reared finfish

Indication

For the control of mortality due to columnaris disease associated with Flavobacterium columnare.

Dosage

10-15 mg/kg body weight/day for 10 consecutive days

Limitations

Catfish

Indication

For the control of mortality due to enteric septicemia of catfish associated with Edwardsiella ictaluri.

Dosage

10-15 mg/kg body weight/day for 10 consecutive days

Limitations

Freshwater-reared warmwater finfish

Indication

For the control of mortality due to streptococcal septicemia associated with Streptococcus iniae.

Dosage

15 mg/kg body weight/day for 10 consecutive days

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Beef And Non-Lactating Dairy

Composition / specifications

300 mg/mL

Beef and non-lactating dairy cattle

Indication

Dosage

Limitations

Indication

For the control of respiratory disease in cattle at high risk of developing BRD associated with Mannheimia haemolytica, Pasteurella multocida, and Histophilus somni.

Dosage

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Beef, excluding veal calves • Dairy, females Under 20 months of age

Composition / specifications

Each milliliter of sterile solution contains 300 milligrams of florfenicol.

Cattle (Beef and Non-Lactating Dairy)

Indication

For control of respiratory disease in cattle at high risk of developing BRD associated with Mannheimia haemolytica, Pasteurella multocida, and Histophilus somni.

Dosage

Administer by a single subcutaneous injection to cattle at a dose rate of 40 mg/kg body weight. Do not administer more than 10 mL at each site. The injection should be given only in the neck.

Limitations

Indication

For treatment of bovine respiratory disease (BRD) associated with Mannheimia haemolytica, Pasteurella multocida, and Haemophilus somni.

Dosage

Limitations

Indication

For treatment of bovine interdigital phlegmon (foot rot, acute interdigital necrobacillosis, infectious pododermatitis) associated with Fusobacterium necrophorum and Bacteroides melaninogenicus.

Dosage

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Beef And Non-Lactating Dairy

Composition / specifications

300 mg/mL

Beef and non-lactating dairy cattle

Indication

Dosage

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Finfish, Freshwater-Reared • Salmonids, Freshwater-Reared • Catfish • Warmwater Finfish, Freshwater-Reared

Composition / specifications

Type A medicated article containing 500 grams florfenicol per kilogram.

Freshwater-reared warmwater finfish

Indication

For the control of mortality due to streptococcal septicemia associated with Streptococcus iniae

Dosage

15 mg florfenicol per kg of fish

Limitations

Catfish

Indication

For the control of mortality due to enteric septicemia of catfish associated with Edwardsiella ictaluri.

Dosage

10 to 15 milligrams (mg) florfenicol per kilogram (kg) of fish

Limitations

Feed containing florfenicol shall not be fed for more than 10 days. Following administration, fish should be reevaluated by a licensed veterinarian before initiating a further course of therapy. A dose-related decrease in hematopoietic/lymphopoietic tissue may occur. The time required for hematopoietic/lymphopoietic tissues to regenerate was not evaluated. Not for use in animals intended for breeding purposes. The effects of florfenicol on reproductive performance have not been determined. Toxicity studies in dogs, rats, and mice have associated the use of florfenicol with testicular degeneration and atrophy. Federal law limits this drug to use under the professional supervision of a licensed veterinarian. See Sec. 558.6 of this chapter for additional requirements. The expiration date of veterinary feed directives (VFDs) for florfenicol must not exceed 6 months from the date of issuance. VFDs for florfenicol shall not be refilled.

Finfish

Indication

For the control of mortality due to columnaris disease associated with Flavobacterium columnare.

Dosage

10 to 15 mg florfenicol per kg of fish

Limitations

Salmonids

Indication

For the control of mortality due to coldwater disease associated with Flavobacterium psychrophilum and furunculosis associated with Aeromonas salmonicida.

Dosage

10 to 15 mg florfenicol per kg of fish

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Beef And Non-Lactating Dairy

Label highlights

Indication

Dosage

For treatment of bovine respiratory disease (BRD) and bovine interdigital phlegmon (foot rot):

For control of respiratory disease in cattle at high-risk of developing BRD:

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: No use class stated or implied

Composition / specifications

Type A medicated article containing florfenicol at 18.2 g/lb (40 g/kg).

Swine

Indication

Dosage

Feed 182 grams per ton of feed (200 parts per million) continuously as the sole ration for 5 days.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: No use class stated or implied

Composition / specifications

23 mg florfenicol/ml

Swine

Indication

For the treatment of swine respiratory disease associated with Actinobacillus pleuropneumoniae, Pasteurella multocida, Salmonella choleraesuis, and Streptococcus suis in swine.

Dosage

Dilute to 400 mg/gallon of water (100 ppm) and administer as the only source of drinking water for five (5) consecutive days.

Limitations

Not for use in swine intended for breeding. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

FDA page: Open in Animal Drugs @ FDA

Species: No use class stated or implied

Composition / specifications

23 mg florfenicol/mL

Label highlights

Indication

For the treatment of swine respiratory disease associated with Actinobacillus pleuropneumoniae, Pasteurella multocida, Salmonella choleraesuis, and Streptococcus suis in swine.

Dosage

400 mg per gallon of water (100 parts per million (ppm)) provided in the drinking water for 5 consecutive days.

Limitations

Federal law restricts this drug to use by or on the order of a licensed veterinarian

FDA page: Open in Animal Drugs @ FDA

Species: No use class stated or implied

Composition / specifications

Each milliliter contains 23 milligrams florfenicol.

Swine

Indication

For the treatment of swine respiratory disease (SRD) associated with Actinobacillus pleuropneumoniae, Pasteurella multocida, Salmonella choleraesuis and Streptococcus suis.

Dosage

Administer in drinking water ad libitum at 400 mg per gallon (100 parts per million) for 5 consecutive days.

Limitations

Federal law restricts this drug to use by or on the order of a licensed veterinarian.

FDA page: Open in Animal Drugs @ FDA

Species: Beef • Dairy, females Under 20 months of age

Composition / specifications

Each mL of solution contains 300 mg florfenicol in the inactive vehicles 2-pyrrolidone and triacetin.

Cattle (Beef and Non-Lactating Dairy)

Indication

Dosage

40 mg/kg body weight (6 mL/100 lb) as a single subcutaneous injection.

Limitations

FDA page: Open in Animal Drugs @ FDA

Usage

Source: FDA Animal Drugs @ FDA • Reference

Contraindications

Top Reported Reactions (openFDA)

De-duplicated reaction terms grouped by body system from FDA openFDA reports (not verified; does not prove causation).

Digestive

Loss of appetite (1) • Cat Decreased appetite (1) • Cat Bloody diarrhoea (1) • Dog

Showing top 5 for Digestive.

Skin & allergy

Hair loss at application site (1) • Dog Application site swelling (1) • Cat

Showing top 5 for Skin & allergy.

Neurologic

Unsteady walking (1) • Cat Head tilt - neurological disorder (1) • Cat Circling - neurological disorder (1) • Cat

Showing top 5 for Neurologic.

Other

Hind limb paresis (1) • Dog High blood pressure (1) • Dog Hiding (1) • Cat Head tilt - ear disorder (1) • Dog Head shake - ear disorder (1) • Cat

Show more (19)

General pain (1) • Cat Falling (1) • Cat Eosinophilia (1) • Dog Eosinopenia (1) • Cat Enamel disorder (1) • Dog Elevated temperature (1) • Dog Elevated blood urea nitrogen (1) • Cat Dull (1) • Dog Dilated pupils (1) • Dog Dehydration (1) • Cat Decreased activity (1) • Dog Death by euthanasia (1) • Cat Deafness (1) • Dog Cough (1) • Cat Basophilia (1) • Cat Balance problem (1) • Cat Application site pain (1) • Cat Anisocoria (1) • Cat Abnormal radiograph finding (1) • Cat

Showing top 5 for Other.

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Adverse Event Case Summaries (openFDA)

These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.

No case-level openFDA reports are linked for this medication yet.

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Overdose Information

No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.

Storage & Handling

No approved storage guidance is linked yet for this ingredient. Use manufacturer packaging and veterinary guidance for handling/storage.

Share Your Thoughts

Let others know your experience or advice regarding this medication.

No community reviews yet. Be the first to share your experience.

This medication has not been reviewed by a veterinarian yet.

Medical Disclaimer: The medication details provided on Roxee are for informational purposes only and are not a substitute for professional veterinary advice. Always consult your veterinarian about your pet's specific needs.

Florfenicol

Data freshness

Evidence

Florfenicol

Medication Snapshot

Florfenicol

Indications / Uses

Warnings / Contraindications

Side Effects

FAQ

What species is this commonly shown for?

Does this usually require a prescription?

What dosage forms are listed?

Related Conditions

Source Transparency

Add to My Pet's Meds

Pet Owner Quick Guide

Quick Facts

Warnings / Contraindications

Adverse Reactions

Grouped by Body System

Most Reported Reactions

Documents

Owner handouts

Official label / PI

SPL

FOI

141-063

141-063

141-246

141-246

141-246

141-246

141-246

141-246

141-246

141-246

141-246

141-246

Loncor® 300

Loncor® 300

Beef and non-lactating dairy cattle

PAQFLOR™

PAQFLOR™

Freshwater-reared salmonids

Freshwater-reared finfish

Catfish

Freshwater-reared warmwater finfish

FLORFENICOL INJECTION

FLORFENICOL INJECTION

Beef and non-lactating dairy cattle

Nuflor®

Nuflor® Nuflor®-S

Cattle (Beef and Non-Lactating Dairy)

Nuflor®-S

Nuflor® Nuflor®-S

Cattle (Beef and Non-Lactating Dairy)

Florfeniject™

Florfeniject™

Beef and non-lactating dairy cattle

Aquaflor® Type A Medicated Article

Aquaflor® Type A Medicated Article

Freshwater-reared warmwater finfish

Catfish

Finfish

Salmonids

Norfenicol®

Norfenicol®

Label highlights

Nuflor®

Nuflor®

Swine

FLORCON

FLORCON

Swine

Florvio™ 2.3% Concentrate Solution

Florvio™ 2.3% Concentrate Solution

Label highlights

Nuflor® Concentrate Solution

Nuflor® Concentrate Solution