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Amoxicillin, Clavulanate

Detailed information about Amoxicillin, Clavulanate

Official label facts Owner quick guide first Marketing clearly labeled
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Reviewed / Updated / Sources

Reviewed: Not available

Updated: February 12, 2026, 10:44 PM UTC

Sources:

Pet Owner Quick Guide

Start here first for the simple next-step summary.

Used for:

Your vet decides this. Here's what owners typically ask/watch for.

What to watch for:

  • wobbly/unsteady walking (1 reports)
  • Erythematous rash (1 reports)
  • Erosion (1 reports)

When to call the vet:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
  • Facial swelling or hives.
  • Blood in vomit or stool.

What to ask your vet today:

  • Is this medicine the right fit for my pet’s current symptoms?
  • Which warning signs mean I should call back right away?
  • How should I handle missed doses or refusal to take the medicine?
Safety & side effects

What to watch:

  • wobbly/unsteady walking
  • Erythematous rash
  • Erosion

Most reported reactions:

  • Unsteady walking (ataxia) (1 reports)
  • Erythematous rash (1 reports)
  • Erosion (1 reports)

When to call your vet:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
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Data freshness: source data appears current.

Latest refresh: Mar 21, 2026, 10:01 a.m.

Data freshness
  • Medication catalog: Source Roxee | Refreshed Feb 12, 2026, 10:44 PM UTC
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed Mar 21, 2026, 10:01 AM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
  • openFDA reaction terms: Source FDA openFDA | Refreshed Feb 9, 2026, 3:13 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Feb 9, 2026, 3:20 AM UTC
Image coming soon
Amoxicillin, Clavulanate

Amoxicillin, Clavulanate

Drug type: Generic ingredient • Generic profile • No FDA branded products linked

Species: Both

Manufacturer: Not available (source)

Quick Facts

Official label facts first, then secondary summaries. Marketing content is separated below.

Species: Both
Manufacturer: Not available

Adverse Reactions

Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.

Tap or hover a reaction to see what it means in plain language.

Tracked signals
32
Reported cases
32
Serious reports
32
Species represented
2
Grouped by Body System
Digestive (2) · Decreased appetite, Appetite disorder NOS Skin & allergy (1) · Erythematous rash Neurologic (2) · Unsteady walking (ataxia), Depression Behavior (1) · Behavioral disorder (unspecified) Other (26) · Erosion, Elevated total bilirubin, Elevated liver enzymes
Most Reported Reactions
Reaction Body system Cases Species Serious cases
Neurologic 1 Dog 1
Skin & allergy 1 Cat 1
Other 1 Cat 1
Other 1 Dog 1
Other 1 Dog 1
Other 1 Dog 1
Other 1 Dog 1
Other 1 Dog 1

Species coverage: Dog (28) Cat (4)

View detailed reaction table
Reaction Body system Species Seriousness Frequency Reports
Neurologic Dog Serious - 1
Skin & allergy Cat Serious - 1
Other Cat Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Neurologic Dog Serious - 1
Other Dog Serious - 1
Digestive Dog Serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Behavior Dog Serious - 1
Digestive Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Source metadata:
Veterinary reference (advanced)

Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.

At a Glance

Quick facts and links to official labeling and safety signals.

Data freshness
  • Medication catalog: Source Roxee | Refreshed Feb 12, 2026, 10:44 PM UTC
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed Mar 21, 2026, 10:01 AM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
  • openFDA reaction terms: Source FDA openFDA | Refreshed Feb 9, 2026, 3:13 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Feb 9, 2026, 3:20 AM UTC
Official (FDA)
Identity: Generic ingredient • No FDA branded products linked
No official FDA brand rows linked yet for this ingredient.
Case-reported brands (openFDA): MSK
Catalog species: Both
Safety (openFDA)
Top reactions: Dog 8 • Cat 8 • View
Case summaries: 6 (showing 6) • View
openFDA reports are unverified and do not prove causation.
Diagnosis Codes

Diagnosis-code mappings are not available for this medication yet.

Counseling and Monitoring Highlights

Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.

Top reaction signals
Unsteady walking (ataxia) (1) Erythematous rash (1) Erosion (1) Elevated total bilirubin (1) Elevated liver enzymes (1) Elevated lactate (1) Elevated gamma-glutamyl transferase (1) Elevated blood urea nitrogen (1)

Data Sources & Change Log

Every non-trivial field is expected to include provenance and update timestamps.

Official 1 Clinical 0 Manufacturer 0 Marketing 0
Current Field Facts
  • side_effects: Top reported reactions (openFDA): Elevated blood urea nitrogen (BUN), Hypoalbuminaemia, Not eating, Vomiting, Abnormal radiograph finding, Depression. (Official, 2026-02-12)
Recent Revisions
  • side_effects updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields

Top Reported Reactions (openFDA)

De-duplicated reaction terms grouped by body system from FDA openFDA reports (not verified; does not prove causation).

Digestive
Decreased appetite (1) • Dog Appetite disorder NOS (1) • Dog

Showing top 5 for Digestive.

Skin & allergy
Erythematous rash (1) • Cat

Showing top 5 for Skin & allergy.

Neurologic
Unsteady walking (1) • Dog Depression (1) • Dog

Showing top 5 for Neurologic.

Behavior
Behavioral disorder (1) • Dog

Showing top 5 for Behavior.

Other
Erosion (1) • Cat Elevated total bilirubin (1) • Dog Elevated liver enzymes (1) • Dog Elevated lactate (1) • Dog Elevated gamma-glutamyl transferase (1) • Dog
Show more (21)
Elevated blood urea nitrogen (1) • Dog Elevated bile acids (1) • Dog Elevated alanine aminotransferase (1) • Dog Duodenal ulcer (1) • Dog Dermatitis (1) • Cat Decreased urine concentration (1) • Dog Death by euthanasia (1) • Dog Crying (1) • Cat Collapse NOS (1) • Dog Cerebral vascular accident (1) • Dog Blood in urine (1) • Dog Apathy (1) • Dog Agitation (1) • Dog Administration error NOS (1) • Dog Addisonian crisis (1) • Dog Addison's disease (1) • Dog Abnormal ultrasound finding (1) • Dog Abnormal radiograph finding (1) • Dog Abnormal menace reflex test (1) • Dog Abnormal adrenocorticotropic hormone (ACTH) stimulation test (1) • Dog Abdominal cavity disorder NOS (1) • Dog

Showing top 5 for Other.

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Adverse Event Case Summaries (openFDA)

These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.

Dog, ['Retriever - Labrador', 'Dog (unknown)'], Female, 11 year, 24.1 kilogram • Drug: MSK • Reactions: Not eating, Collapse NOS, Elevated lactate, Hyperglycaemia, Urinary tract infection… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2024-US-080055
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 11.00 Year
  • Weight: 24.100 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
Reactions Reported:
Not eating Collapse NOS Elevated lactate Hyperglycaemia Urinary tract infection Abnormal adrenocorticotropic hormone (ACTH) stimulation test Hypocortisolaemia Addison's disease Elevated blood urea nitrogen Decreased urine concentration Infectious disease NOS Decreased appetite Tiredness Sleepiness - systemic disorder Appetite disorder NOS Addisonian crisis Polyuria Polydipsia Panting Hypochloraemia Weight loss Sickness Hyponatremia Hyperchloraemia
Outcomes: Ongoing

Cat, Ragdoll, Female, 10 year, 4.536 kilogram • Drug: MSK • Reactions: Erythematous rash, Localised hair loss, Self trauma, Skin ulcer, Skin reaction NOS… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2023-US-066044
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 10.00 Year
  • Weight: 4.536 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
Reactions Reported:
Erythematous rash Localised hair loss Self trauma Skin ulcer Skin reaction NOS Behavioral disorder (unspecified) Crying Haemorrhage NOS Dermatitis Erosion Panniculitis Itching Tiredness (lethargy) Weight loss Skin inflammation NOS Licking Uncomfortable Localised allergic oedema NOS
Outcomes: Ongoing

Dog, Saint Bernard Dog, Male, 2 year, 53.524 kilogram • Drug: MSK, Unassigned, Oral • Reactions: Vomiting, Not eating, Subdued, Haemoconcentration, Leucocytosis NOS… • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2023-US-040236
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 2.00 Year
  • Weight: 53.524 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Unassigned
Reactions Reported:
Vomiting Not eating Subdued Haemoconcentration Leucocytosis NOS Neutrophilia Depression Elevated blood urea nitrogen Hypoalbuminaemia Abnormal radiograph finding Fluid in abdomen NOS Peritonitis Duodenal ulcer Elevated liver enzymes Prolonged one stage prothrombin time
Outcomes: Outcome Unknown

Dog, Saint Bernard Dog, Male, 2 year, 53.524 kilogram • Drug: MSK, Unassigned, Oral • Reactions: Vomiting, Not eating, Subdued, Haemoconcentration, Leucocytosis NOS… • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2023-US-032443
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 2.00 Year
  • Weight: 53.524 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Unassigned
Reactions Reported:
Vomiting Not eating Subdued Haemoconcentration Leucocytosis NOS Neutrophilia Depression Elevated blood urea nitrogen Hypoalbuminaemia Abnormal radiograph finding Fluid in abdomen NOS Peritonitis Duodenal ulcer Elevated liver enzymes Prolonged one stage prothrombin time INEFFECTIVE, ANTIEMETIC Administration error NOS Abnormal ultrasound finding Abdominal cavity disorder NOS Peritoneal fluid, abnormal NOS
Outcomes: Recovered/Normal

Dog, Chihuahua, Male, 10 year, 3.175 kilogram • Drug: MSK • Reactions: Tiredness (lethargy), Vocalisation, Behavioral disorder (unspecified), Agitation, Blood in urine… • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2017-US-067948
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 10.00 Year
  • Weight: 3.175 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
Reactions Reported:
Tiredness (lethargy) Vocalisation Behavioral disorder (unspecified) Agitation Blood in urine Stranguria Vomiting Polydipsia Elevated alanine aminotransferase Elevated gamma-glutamyl transferase Elevated bile acids Elevated total bilirubin Hypoalbuminaemia Other abnormal test result NOS Increased packed cell volume
Outcomes: Recovered/Normal

Dog, Spaniel - Cocker English, Unknown, 11 year, 16 kilogram • Drug: MSK, Implant, Unknown • Reactions: Trembling, Apathy, Unsteady walking (ataxia), Proprioception loss, Unable to rise… • Outcome: Euthanized

  • Report ID: FRA-USFDACVM-2016-FR-000070
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Unknown
  • Age: 11.00 Year
  • Weight: 16.000 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Implant
Reactions Reported:
Trembling Apathy Unsteady walking (ataxia) Proprioception loss Unable to rise Impaired vision Abnormal menace reflex test Death by euthanasia Cerebral vascular accident
Outcomes: Euthanized

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Overdose Information

No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.

Storage & Handling

No approved storage guidance is linked yet for this ingredient. Use manufacturer packaging and veterinary guidance for handling/storage.

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