Skip to main content
Start triage

Start triage first, then route to emergency care.

Start symptom intake Emergency vets near you

Need urgent help? Start triage first, then route to emergency care.

Start symptom intake Emergency vets near you

Meds A-Z

Febantel

Detailed information about Febantel

Official label facts Owner quick guide first Marketing clearly labeled
Talk to a Vet / Find a Vet Near You Start Symptom Intake

Veterinary professional?

Showing simplified owner view. Switch to Vet View for full technical detail.

Add to My Pet's Meds

Choose a pet, confirm current or past, and optionally add reminder notes.

Sign in to save this medication to your pet profile.

Sign in to continue

Reviewed / Updated / Sources

Reviewed: Not available

Updated: February 12, 2026, 10:44 PM UTC

Sources:

Pet Owner Quick Guide

Start here first for the simple next-step summary.

Used for:

For the removal of tapeworms ( Dipylidium caninum , Taenia pisiformis , Echinococcus granulosus ); hookworms ( Ancylostoma caninum , Uncinaria stenocephala ); ascarids ( Toxocara canis , Toxascaris leonina ); and whipwor...

What to watch for:

  • The paste may be administered on the base of the tongue or well mixed into a portion of the normal grain ration
  • For animals maintained on premises where reinfection is likely to occur, re-treatment may be necessary
  • For most effective results, retreat in 6 to 8 weeks
  • Not for use in horses intended for food
  • Consult your veterinarian for assistance in the diagnosis treatment, and control of parasitism
  • Administer by stomach tube or drench, or by mixing well into a portion of the normal grain ration
  • Febantel suspension may be used in combination with trichlorfon oral liquid when combining 1 part febantel suspension with 5 parts trichlorfon liquid
  • Do not use in pregnant animals
  • Consider alternative therapy or use with caution in animals with pre-existing liver or kidney dysfunction
  • very low energy (1 reports)
  • Soft stool (1 reports)
  • Pericardial effusion (1 reports)

When to call the vet:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
  • Facial swelling or hives.
  • Blood in vomit or stool.

Regulatory restrictions are shown in Vet View.

What to ask your vet today:

  • Is this medicine the right fit for my pet’s current symptoms?
  • Which warning signs mean I should call back right away?
  • How should I handle missed doses or refusal to take the medicine?
Safety & side effects

What to watch:

  • The paste may be administered on the base of the tongue or well mixed into a portion of the normal grain ration
  • For animals maintained on premises where reinfection is likely to occur, re-treatment may be necessary
  • For most effective results, retreat in 6 to 8 weeks
  • Not for use in horses intended for food
  • Consult your veterinarian for assistance in the diagnosis treatment, and control of parasitism

Most reported reactions:

  • Tiredness (lethargy) (1 reports)
  • Soft stool (1 reports)
  • Pericardial effusion (1 reports)

When to call your vet:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
Talk to a Vet / Find a Vet Near You Start Symptom Intake

Data freshness: source data appears current.

Latest refresh: Mar 21, 2026, 10:02 a.m.

Data freshness
  • Medication catalog: Source Roxee | Refreshed Feb 12, 2026, 10:44 PM UTC
  • Animal Drugs @ FDA: Source FDA | Refreshed Mar 21, 2026, 10:00 AM UTC
    Applications/products are imported from FDA export data.
  • Animal Drugs @ FDA previews: Source FDA | Refreshed Feb 9, 2026, 3:05 AM UTC
    Label highlights/doc links are fetched from FDA preview endpoints.
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed Mar 21, 2026, 10:01 AM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
  • openFDA reaction terms: Source FDA openFDA | Refreshed Mar 21, 2026, 10:02 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Mar 3, 2026, 11:05 AM UTC
Image coming soon
Febantel

Febantel

Drug type: Generic ingredient • Branded profile • FDA branded products available

Species: Both

Manufacturer: Elanco US Inc.

Quick Facts

Official label facts first, then secondary summaries. Marketing content is separated below.

Species: Both
Manufacturer: Elanco US Inc.
Form: Liquid (Suspension), Paste, Tablet
Identifiers:
NADA: 107345 NADA: 107346 NADA: 131412 NADA: 133953 NADA: 140912 NADA: 141007 NDC Package: 30798-201-63 NDC Package: 30798-202-61 NDC Package: 30798-203-61 NDC Package: 52133-0047-0 NDC Package: 58198-0056-1 NDC Package: 58198-0056-2 NDC Package: 58198-0057-1 NDC Package: 58198-0057-2 NDC Package: 58198-0058-1 NDC Package: 58198-0058-2 NDC Package: 58198-0065-1 NDC Package: 58198-0066-1 NDC Package: 58198-0067-1 NDC Package: 58198-0068-1
Source metadata:

Warnings / Contraindications

The paste may be administered on the base of the tongue or well mixed into a portion of the normal grain ration. For animals maintained on premises where reinfection is likely to occur, re-treatment may be necessary. For most effective results, retreat in 6 to 8 weeks. Not for use in horses intended for food. Consult your veterinarian for assistance in the diagnosis treatment, and control of parasitism. Administer by stomach tube or drench, or by mixing well into a portion of the normal grain ration. For animals maintained on premises where reinfection is likely to occur, re-treatment may be necessary. For most effective results, retreat in 6 to 8 weeks. Not for use in horses intended for food. Federal law restricts this drug to use by or on the order of a licensed veterinarian. Febantel suspension may be used in combination with trichlorfon oral liquid when combining 1 part febantel suspension with 5 parts trichlorfon liquid. Do not use in pregnant animals. Federal law restricts this drug to use by or on the order of a licensed veterinarian. Consider alternative therapy or use with caution in animals with pre-existing liver or kidney dysfunction.

  • High: The paste may be administered on the base of the tongue or well mixed into a portion of the normal grain ration. For animals maintained on premises where reinfection is likely to occur, re-treatment may be necessary. For most effective results, retreat in 6 to 8 weeks. Not for use in horses intended for food. Consult your veterinarian for assistance in the diagnosis treatment, and control of parasitism. Administer by stomach tube or drench, or by mixing well into a portion of the normal grain ration. For animals maintained on premises where reinfection is likely to occur, re-treatment may be necessary. For most effective results, retreat in 6 to 8 weeks. Not for use in horses intended for food. Federal law restricts this drug to use by or on the order of a licensed veterinarian. Febantel suspension may be used in combination with trichlorfon oral liquid when combining 1 part febantel suspension with 5 parts trichlorfon liquid. Do not use in pregnant animals. Federal law restricts this drug to use by or on the order of a licensed veterinarian. Consider alternative therapy or use with caution in animals with pre-existing liver or kidney dysfunction.
Source metadata:

Adverse Reactions

Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.

Tap or hover a reaction to see what it means in plain language.

Tracked signals
32
Reported cases
32
Serious reports
11
Species represented
2
Grouped by Body System
Digestive (4) · Vomiting, Partial anorexia, Loss of appetite Neurologic (1) · Tiredness (lethargy) Behavior (1) · Behavioral disorder (unspecified) Effectiveness (2) · Lack of efficacy - NOS, Lack of efficacy (endoparasite) - hookworm Other (24) · Weight loss, Unclassifiable adverse event, Soft stool
Most Reported Reactions
Reaction Body system Cases Species Serious cases
Neurologic 1 Dog 1
Other 1 Dog 1
Other 1 Dog 1
Other 1 Dog 1
Other 1 Dog 1
Other 1 Dog 1
Other 1 Dog 1
Other 1 Dog 1

Species coverage: Dog (18) Cat (14)

View detailed reaction table
Reaction Body system Species Seriousness Frequency Reports
Other Cat Non-serious - 1
Digestive Cat Non-serious - 1
Other Cat Non-serious - 1
Neurologic Dog Serious - 1
Other Dog Serious - 1
Other Cat Non-serious - 1
Other Dog Serious - 1
Digestive Cat Non-serious - 1
Other Dog Serious - 1
Other Dog Non-serious - 1
Other Dog Non-serious - 1
Other Cat Non-serious - 1
Other Cat Non-serious - 1
Other Cat Non-serious - 1
Other Dog Non-serious - 1
Digestive Cat Non-serious - 1
Effectiveness Cat Non-serious - 1
Effectiveness Dog Non-serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Cat Non-serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Digestive Cat Non-serious - 1
Other Dog Non-serious - 1
Other Dog Serious - 1
Other Dog Non-serious - 1
Behavior Dog Non-serious - 1
Other Cat Non-serious - 1
Other Cat Non-serious - 1
Source metadata:

Documents

Owner handouts and official technical documents are grouped for faster access.

Owner handouts (0)
  • No owner handouts linked yet.
Official label / PI (0)
  • No official label or package insert links yet.
SPL (10)
  • Drontal™ Plus Taste Tabs™ · SPL
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/spl/file/1392/Drontal%E2%84%A2%20Plus%20Taste%20Tabs%E2%84%A2
  • Drontal™ Plus · SPL
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/spl/file/1391/Drontal%E2%84%A2%20Plus
  • Quad Dewormer · SPL
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/spl/file/1393/Quad%20Dewormer
  • Vercom Paste Anthelmintic · SPL
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/spl/file/2047/Vercom%20Paste%20Anthelmintic
  • Negabot Plus Paste · SPL
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/spl/file/540/Negabot%20Plus%20Paste
  • Combotel · SPL
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/spl/file/539/Combotel
  • Rintal® Paste · SPL
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/spl/file/1612/Rintal%C2%AE%20Paste
  • Cutter Paste · SPL
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/spl/file/1611/Cutter%20Paste
  • Rintal® Suspension · SPL
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/spl/file/1624/Rintal%C2%AE%20Suspension
  • Rintal® Tabs Anthelmintic Tablets · SPL
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/spl/file/1364/Rintal%C2%AE%20Tabs%20Anthelmintic%20Tablets
FOI (6)
  • ucm116081.pdf · FOI
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/document/downloadFoi/557
  • ucm116050.pdf · FOI
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/document/downloadFoi/556
  • N141007_Supp_03-28-1996.pdf · FOI
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/document/downloadFoi/2505
  • N141007_Orig_5_19_1994.pdf · FOI
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/document/downloadFoi/3619
  • N133953_Supp_09_12_1991.pdf · FOI
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/document/downloadFoi/1635
  • UCM478240.pdf · FOI
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/document/downloadFoi/526
Source metadata:
Veterinary reference (advanced)

Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.

At a Glance

Quick facts and links to official labeling and safety signals.

Data freshness
  • Medication catalog: Source Roxee | Refreshed Feb 12, 2026, 10:44 PM UTC
  • Animal Drugs @ FDA: Source FDA | Refreshed Mar 21, 2026, 10:00 AM UTC
    Applications/products are imported from FDA export data.
  • Animal Drugs @ FDA previews: Source FDA | Refreshed Feb 9, 2026, 3:05 AM UTC
    Label highlights/doc links are fetched from FDA preview endpoints.
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed Mar 21, 2026, 10:01 AM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
  • openFDA reaction terms: Source FDA openFDA | Refreshed Mar 21, 2026, 10:02 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Mar 3, 2026, 11:05 AM UTC
Official (FDA)
Identity: Generic ingredient • FDA branded products available
Official FDA brands: Drontal™ Plus Taste Tabs™ Drontal™ Plus Quad Dewormer Negabot Plus Paste Combotel Rintal® Paste Cutter Paste Rintal® Suspension Rintal® Tabs Anthelmintic Tablets Vercom Paste Anthelmintic
Case-reported brands (openFDA): MSK
Catalog species: Both • FDA-labeled species: Cat, Dog, Dog And Puppy, Horse, Pony
Rx/OTC: OTC, RX
Form/route: Liquid (Suspension), Paste, Tablet • Nasogastric, Oral
Applications: NADA 141-007 • NADA 133-953 • NADA 131-412 • NADA 107-345 • NADA 107-346 • NADA 140-912
Documents: 6 (FOI: 6) • SPL: 10 • Label highlights • Official documents
Safety (openFDA)
Top reactions: Dog 16 • Cat 8 • View
Case summaries: 13 (showing 8) • View
openFDA reports are unverified and do not prove causation.
Diagnosis Codes

Diagnosis-code mappings are not available for this medication yet.

Counseling and Monitoring Highlights

Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.

Owner-facing counseling points
  • The paste may be administered on the base of the tongue or well mixed into a portion of the normal grain ration. For animals maintained on premises where reinfection is likely to occur, re-treatment may be necessary. For most effective results, retreat in 6 to 8 weeks. Not for use in horses intended for food. Consult your veterinarian for assistance in the diagnosis treatment, and control of parasitism. Administer by stomach tube or drench, or by mixing well into a portion of the normal grain ration. For animals maintained on premises where reinfection is likely to occur, re-treatment may be necessary. For most effective results, retreat in 6 to 8 weeks. Not for use in horses intended for food. Federal law restricts this drug to use by or on the order of a licensed veterinarian. Febantel suspension may be used in combination with trichlorfon oral liquid when combining 1 part febantel suspension with 5 parts trichlorfon liquid. Do not use in pregnant animals. Federal law restricts this drug to use by or on the order of a licensed veterinarian. Consider alternative therapy or use with caution in animals with pre-existing liver or kidney dysfunction. (Contraindication, High)
Top reaction signals
Tiredness (lethargy) (1) Soft stool (1) Pericardial effusion (1) Pancytopenia (1) Increased respiratory rate (1) Inappropriate urination (1) Fluid in abdomen NOS (1) Febrile (1)

Identifiers & Packages

Normalized identifiers (NDC/NADA/ANADA) and package metadata from regulator listings.

Identifiers
NADA: 107345 NADA: 107346 NADA: 131412 NADA: 133953 NADA: 140912 NADA: 141007 NDC Package: 30798-201-63 NDC Package: 30798-202-61 NDC Package: 30798-203-61 NDC Package: 52133-0047-0 NDC Package: 58198-0056-1 NDC Package: 58198-0056-2 NDC Package: 58198-0057-1 NDC Package: 58198-0057-2 NDC Package: 58198-0058-1 NDC Package: 58198-0058-2 NDC Package: 58198-0065-1 NDC Package: 58198-0066-1 NDC Package: 58198-0067-1 NDC Package: 58198-0068-1 NDC Package: 58198-0069-1 NDC Package: 58198-0070-1 NDC Package: 62157-442-01 NDC Product: 30798
Package NDC Product NDC Form / Route Status
30798-201-63 30798 -
30798-202-61 30798 -
30798-203-61 30798 -
52133-0047-0 52133 -
58198-0056-1 58198 -
58198-0056-2 58198 -
58198-0057-1 58198 -
58198-0057-2 58198 -
58198-0058-1 58198 -
58198-0058-2 58198 -
58198-0065-1 58198 -
58198-0066-1 58198 -
58198-0067-1 58198 -
58198-0068-1 58198 -
58198-0069-1 58198 -
58198-0070-1 58198 -
62157-442-01 62157 -

Enriched Documents

Documents are tiered by source trust: Official, Clinical, Manufacturer, Marketing.

  • N141007_Orig_5_19_1994.pdf • FOI summary • Official • June 15, 2022
    FDA FOI summary for application 141007
  • N141007_Supp_03-28-1996.pdf • FOI summary • Official • June 15, 2022
    FDA FOI summary for application 141007
  • ucm116050.pdf • FOI summary • Official • June 15, 2022
    FDA FOI summary for application 141007
  • ucm116081.pdf • FOI summary • Official • June 15, 2022
    FDA FOI summary for application 141007
  • N133953_Supp_09_12_1991.pdf • FOI summary • Official • July 10, 2017
    FDA FOI summary for application 133953
  • UCM478240.pdf • FOI summary • Official • June 1, 2016
    FDA FOI summary for application 140912

Data Sources & Change Log

Every non-trivial field is expected to include provenance and update timestamps.

Official 9 Clinical 0 Manufacturer 0 Marketing 0
Current Field Facts
  • contraindications: The paste may be administered on the base of the tongue or well mixed into a portion of the normal grain ration. For animals maintained on premises where reinf… (Official, 2026-02-12)
  • side_effects: Top reported reactions (openFDA): Vomiting, Emesis (multiple), Emesis, Diarrhoea, Lack of efficacy (endoparasite) - tapeworm, Lethargy (see also Central nervou… (Official, 2026-02-12)
  • usage: For removal of large strongyles (Strongylus vulgaris S. edentatus, S. equinus); ascarids (Parascaris equorum, sexually mature and immature); pinworms (Oxyuris … (Official, 2026-02-12)
Recent Revisions
  • side_effects updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields
  • usage updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields

FDA Products & Applications (Animal Drugs @ FDA)

Official sponsor/proprietary-name/application-status records linked by active ingredient.

Product Sponsor Application Status Published
Drontal™ Plus Taste Tabs™ Drontal™ Plus Quad Dewormer
RX
Febantel Praziquantel Pyrantel Pamoate
Tablet • Oral
Label highlights
Official documents
Elanco US Inc. NADA 141-007 Approved Jun 15, 2022
Vercom Paste Anthelmintic
RX
Febantel Praziquantel
Paste • Oral
Label highlights
Official documents
Elanco US Inc. NADA 133-953 Approved Jul 10, 2017
Negabot Plus Paste Combotel
OTC
Febantel Trichlorfon
Official documents
Bayer HealthCare LLC, Animal Health Division NADA 131-412 W Jun 1, 2016
Rintal® Paste Cutter Paste
OTC
Febantel
Paste • Oral
Label highlights
Official documents
Elanco US Inc. NADA 107-345 Approved Jun 1, 2016
Rintal® Suspension
OTC
Febantel
Liquid (Suspension) • Nasogastric, Oral
Label highlights
Official documents
Elanco US Inc. NADA 107-346 Approved Jun 1, 2016
Rintal® Tabs Anthelmintic Tablets
RX
Febantel
Tablet • Oral
Label highlights
Official documents
Elanco US Inc. NADA 140-912 Approved Jun 1, 2016

Data source: FDA Animal Drugs @ FDA (public search export).

What It's For (FDA Label Highlights)

Extracted from FDA Animal Drugs @ FDA product labeling. Always confirm details with your veterinarian.

Species: Dog, Restricted During Pregnancy • Dog, Excluding Under 2 Pounds • Dog And Puppy, Excluding Under 3 Weeks Age
Composition / specifications
Each tablet contains either:
1) 22.7 milligrams praziquantel, 22.7 milligrams pyrantel base, and 113.4 milligrams febantel
2) 68 milligrams praziquantel, 68 milligrams pyrantel base, and 340.2 milligrams febantel
or
3) 136 milligrams praziquantel, 136 milligrams pyrantel base, and 680.4 milligrams febantel
Dogs: Weighing 2 to 4 pounds (0.9 to 1.8 kilograms)
Indication
For the removal of tapeworms (Dipylidium caninum, Taenia pisiformis, Echinococcus granulosus); hookworms (Ancylostoma caninum, Uncinaria stenocephala); ascarids (Toxocara canis, Toxascaris leonina); and whipworms (Trichuris vulpis) and for removal and control of tapeworm (Echinococcus multilocularis).
Dosage
0.5 Tablet No.1
Limitations
Do not use in pregnant animals. Do not use in dogs weighing less than 2 pounds (0.9 kilogram) or in puppies less than 3 weeks of age. Federal law restricts this drug to use by or on the order of a licensed veterinarian
Dogs: Weighing 5 to 7 pounds (2.3 to 3.2 kilograms):
Indication
For the removal of tapeworms (Dipylidium caninum, Taenia pisiformis, Echinococcus granulosus); hookworms (Ancylostoma caninum, Uncinaria stenocephala); ascarids (Toxocara canis, Toxascaris leonina); and whipworms (Trichuris vulpis) and for removal and control of tapeworm (Echinococcus multilocularis).
Dosage
1 tablet No.1
Limitations
Do not use in pregnant animals. Do not use in dogs weighing less than 2 pounds (0.9 kilogram) or in puppies less than 3 weeks of age. Federal law restricts this drug to use by or on the order of a licensed veterinarian
Dogs: Weighing 8 to 12 pounds (3.6 to 5.4 kilograms)
Indication
For the removal of tapeworms (Dipylidium caninum, Taenia pisiformis, Echinococcus granulosus); hookworms (Ancylostoma caninum, Uncinaria stenocephala); ascarids (Toxocara canis, Toxascaris leonina); and whipworms (Trichuris vulpis) and for removal and control of tapeworm (Echinococcus multilocularis).
Dosage
1.5 tablet No.1
Limitations
Do not use in pregnant animals. Do not use in dogs weighing less than 2 pounds (0.9 kilogram) or in puppies less than 3 weeks of age. Federal law restricts this drug to use by or on the order of a licensed veterinarian
Dogs: Weighing 13 to 18 pounds (5.9 to 8.2 kilograms)
Indication
For the removal of tapeworms (Dipylidium caninum, Taenia pisiformis, Echinococcus granulosus); hookworms (Ancylostoma caninum, Uncinaria stenocephala); ascarids (Toxocara canis, Toxascaris leonina); and whipworms (Trichuris vulpis) and for removal and control of tapeworm (Echinococcus multilocularis).
Dosage
2 tablets No.1
Limitations
Do not use in pregnant animals. Do not use in dogs weighing less than 2 pounds (0.9 kilogram) or in puppies less than 3 weeks of age. Federal law restricts this drug to use by or on the order of a licensed veterinarian
Dogs: Weighing 19 to 25 pounds (8.6 to 11.4 kilograms)
Indication
For the removal of tapeworms (Dipylidium caninum, Taenia pisiformis, Echinococcus granulosus); hookworms (Ancylostoma caninum, Uncinaria stenocephala); ascarids (Toxocara canis, Toxascaris leonina); and whipworms (Trichuris vulpis) and for removal and control of tapeworm (Echinococcus multilocularis).
Dosage
2.5 tablets No.1
Limitations
Do not use in pregnant animals. Do not use in dogs weighing less than 2 pounds (0.9 kilogram) or in puppies less than 3 weeks of age. Federal law restricts this drug to use by or on the order of a licensed veterinarian
Dogs: Weighing 26 to 30 pounds (11.8 to 13.6 kilograms)
Indication
For the removal of tapeworms (Dipylidium caninum, Taenia pisiformis, Echinococcus granulosus); hookworms (Ancylostoma caninum, Uncinaria stenocephala); ascarids (Toxocara canis, Toxascaris leonina); and whipworms (Trichuris vulpis) and for removal and control of tapeworm (Echinococcus multilocularis).
Dosage
1 tablet No.2
Limitations
Do not use in pregnant animals. Do not use in dogs weighing less than 2 pounds (0.9 kilogram) or in puppies less than 3 weeks of age. Federal law restricts this drug to use by or on the order of a licensed veterinarian
Dogs: Weighing 31 to 44 pounds (14.1 to 20.0 kilograms)
Indication
For the removal of tapeworms (Dipylidium caninum, Taenia pisiformis, Echinococcus granulosus); hookworms (Ancylostoma caninum, Uncinaria stenocephala); ascarids (Toxocara canis, Toxascaris leonina); and whipworms (Trichuris vulpis) and for removal and control of tapeworm (Echinococcus multilocularis).
Dosage
1.5 tablets No.2
Limitations
Do not use in pregnant animals. Do not use in dogs weighing less than 2 pounds (0.9 kilogram) or in puppies less than 3 weeks of age. Federal law restricts this drug to use by or on the order of a licensed veterinarian
Dogs: Weighing 45 to 60 pounds (20.4 to 27.2 kilograms)
Indication
For the removal of tapeworms (Dipylidium caninum, Taenia pisiformis, Echinococcus granulosus); hookworms (Ancylostoma caninum, Uncinaria stenocephala); ascarids (Toxocara canis, Toxascaris leonina); and whipworms (Trichuris vulpis) and for removal and control of tapeworm (Echinococcus multilocularis).
Dosage
2.0 tablets No.2 or 1.0 Tablet No. 3
Limitations
Do not use in pregnant animals. Do not use in dogs weighing less than 2 pounds (0.9 kilogram) or in puppies less than 3 weeks of age. Federal law restricts this drug to use by or on the order of a licensed veterinarian
Dogs: Weighing 61 to 90 pounds (27.7 to 40.9 kilograms)
Indication
For the removal of tapeworms (Dipylidium caninum, Taenia pisiformis, Echinococcus granulosus); hookworms (Ancylostoma caninum, Uncinaria stenocephala); ascarids (Toxocara canis, Toxascaris leonina); and whipworms (Trichuris vulpis) and for removal and control of tapeworm (Echinococcus multilocularis).
Dosage
1.5 tablets No. 3
Limitations
Do not use in pregnant animals. Do not use in dogs weighing less than 2 pounds (0.9 kilogram) or in puppies less than 3 weeks of age. Federal law restricts this drug to use by or on the order of a licensed veterinarian
Dogs: Weighing 91 to 120 pounds (41.3 to 54.5 kilograms)
Indication
For the removal of tapeworms (Dipylidium caninum, Taenia pisiformis, Echinococcus granulosus); hookworms (Ancylostoma caninum, Uncinaria stenocephala); ascarids (Toxocara canis, Toxascaris leonina); and whipworms (Trichuris vulpis) and for removal and control of tapeworm (Echinococcus multilocularis).
Dosage
2 tablets No. 3
Limitations
Do not use in pregnant animals. Do not use in dogs weighing less than 2 pounds (0.9 kilogram) or in puppies less than 3 weeks of age. Federal law restricts this drug to use by or on the order of a licensed veterinarian

FDA page: Open in Animal Drugs @ FDA

Species: Dog, Restricted During Pregnancy • Cat, Restricted During Pregnancy
Composition / specifications
Each gram of paste contains 34 milligrams of febantel and 3.4 milligrams of praziquantel.
Dogs (over 6 months of age)
Indication
For removal of hookworms (Ancylostoma caninum and Uncinaria stenocephala), whipworms (Trichuris vulpis), ascarids (Toxocara canis and Toxascaris leonina), and tapeworms (Dipylidium caninum and Taenia pisiformis).
Dosage
10 milligrams of febantel and 1 milligram of praziquantel per kilogram of body weight (1 gram of paste per 7.5 pounds body weight) administered by mouth or in the food once daily for 3 days.
Limitations
Do not use in pregnant animals. Federal law restricts this drug to use by or on the order of a licensed veterinarian. Consider alternative therapy or use with caution in animals with pre-existing liver or kidney dysfunction.
Dogs (puppies less than 6 months of age)
Indication
For removal of hookworms (Ancylostoma caninum and Uncinaria stenocephala), whipworms (Trichuris vulpis), ascarids (Toxocara canis and Toxascaris leonina), and tapeworms (Dipylidium caninum and Taenia pisiformis).
Dosage
15 milligrams of febantel and 1.5 milligrams of praziquantel per kilogram of body weight (1 gram of paste per 5 pounds body weight) administered by mouth on a full stomach once daily for 3 days.
Limitations
Do not use in pregnant animals. Federal law restricts this drug to use by or on the order of a licensed veterinarian. Consider alternative therapy or use with caution in animals with pre-existing liver or kidney dysfunction.
Cats (over 6 months of age)
Indication
For removal of hookworms (Ancylostoma tubaeforme), ascarids (Toxocara cati) and tapeworms (Dipylidium caninum and Taenia taeniaeformis).
Dosage
10 milligrams of febantel and 1 milligram of praziquantel per kilogram of body weight (1 gram of paste per 7.5 pounds body weight) administered by mouth or in the food once daily for 3 days.
Limitations
Do not use in pregnant animals. Federal law restricts this drug to use by or on the order of a licensed veterinarian. Consider alternative therapy or use with caution in animals with pre-existing liver or kidney dysfunction.
Cats (kittens under 6 months of age)
Indication
For removal of hookworms (Ancylostoma tubaeforme), ascarids (Toxocara cati) and tapeworms (Dipylidium caninum and Taenia taeniaeformis).
Dosage
15 milligrams of febantel and 1.5 milligrams of praziquantel per kilogram of body weight (1 gram of paste per 5 pounds body weight) administered by mouth on a full stomach once daily for 3 days.
Limitations
Do not use in pregnant animals. Federal law restricts this drug to use by or on the order of a licensed veterinarian. Consider alternative therapy or use with caution in animals with pre-existing liver or kidney dysfunction.

FDA page: Open in Animal Drugs @ FDA

Species: Horse, Not For Meat Production • Horse, Foals, Not For Food • Pony, Not For Food
Composition / specifications
The drug is a paste containing 45.5 percent febantel.
Horses (and ponies)
Indication
For removal of large strongyles (Strongylus vulgaris S. edentatus, S. equinus); ascarids (Parascaris equorum, sexually mature and immature); pinworms (Oxyuris equi-adult and 4th stage larva); and the various small strongyles in horses, foals, and ponies.
Dosage
6 milligrams per kilogram (2.73 milligrams per pound) of body weight in horses.
Limitations
The paste may be administered on the base of the tongue or well mixed into a portion of the normal grain ration. For animals maintained on premises where reinfection is likely to occur, re-treatment may be necessary. For most effective results, retreat in 6 to 8 weeks. Not for use in horses intended for food. Consult your veterinarian for assistance in the diagnosis treatment, and control of parasitism.

FDA page: Open in Animal Drugs @ FDA

Species: Horse, Not For Meat Production • Horse, Foals, Not For Food • Pony, Not For Food
Composition / specifications
The suspension contains 9.3 percent (2.75 grams per ounce) febantel.
Horses (and ponies)
Indication
For removal of ascarids (Parascaris equorum, adult and sexually immature), pinworms (Oxyuris equi-adult and 4th stage larvae), large strongyles (Strongylus vulgaris, S. edentatus, S. equinus), and the various small strongyles in horses, breeding stallions and mares, pregnant mares, foals, and ponies.
Dosage
3 milliliters per 100 pounds body weight or 1 fluid ounce per 1000 pounds (6 milligrams per kilogram body weight). Allow animal to consume a portion of daily grain ration; administer mixture by stomach tube at rate of 18 milliliters per 100 pounds of body weight.
Limitations
Administer by stomach tube or drench, or by mixing well into a portion of the normal grain ration. For animals maintained on premises where reinfection is likely to occur, re-treatment may be necessary. For most effective results, retreat in 6 to 8 weeks. Not for use in horses intended for food. Federal law restricts this drug to use by or on the order of a licensed veterinarian. Febantel suspension may be used in combination with trichlorfon oral liquid when combining 1 part febantel suspension with 5 parts trichlorfon liquid.

FDA page: Open in Animal Drugs @ FDA

Species: Dog, No Use Class Stated Or Implied • Cat, No Use Class Stated Or Implied
Composition / specifications
Each scored tablet contains 27.2 milligrams of febantel for use in dogs, puppies, cats, and kittens or 163.3 milligrams of febantel for use in dogs, puppies, and cats.
Dogs (Puppies Under 6 Months)
Indication
For removal of hookworms (Ancylostoma caninum and Uncinaria stenocephala), ascarids (Toxocara canis and Toxascaris leonina) and whipworms (Trichuris vulpis).
Dosage
15 milligrams per kilogram body weight. Administer once daily for 3 consecutive days.
Limitations
Do not use in pregnant animals. Consider alternative therapy or use with caution in animals with preexisting liver or kidney dysfunction. Administer to puppies and kittens on a full stomach. Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Dogs (Over 6 Months)
Indication
For removal of hookworms (Ancylostoma caninum and Uncinaria stenocephala), ascarids (Toxocara canis and Toxascaris leonina) and whipworms (Trichuris vulpis).
Dosage
10 milligrams per kilogram body weight. Administer once daily for 3 consecutive days.
Limitations
Do not use in pregnant animals. Consider alternative therapy or use with caution in animals with preexisting liver or kidney dysfunction. Administer to puppies and kittens on a full stomach. Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Cats (Kittens Under 6 Months)
Indication
For removal of hookworms (Ancylostoma tubaeforme) and ascarids (Toxocara cati).
Dosage
15 milligrams per kilogram body weight. Administer once daily for 3 consecutive days.
Limitations
Do not use in pregnant animals. Consider alternative therapy or use with caution in animals with preexisting liver or kidney dysfunction. Administer to puppies and kittens on a full stomach. Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Cats (Over 6 Months)
Indication
For removal of hookworms (Ancylostoma tubaeforme) and ascarids (Toxocara cati).
Dosage
10 milligrams per kilogram body weight. Administer once daily for 3 consecutive days.
Limitations
Do not use in pregnant animals. Consider alternative therapy or use with caution in animals with preexisting liver or kidney dysfunction. Administer to puppies and kittens on a full stomach. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

FDA page: Open in Animal Drugs @ FDA

Official Documents (FDA)

Direct links to FDA-hosted PDFs and SPL packages (when available).

Documents
  • Summary
    This supplement amends the approved NADA by adding a flavored tablet formulation with the same indications.
  • Summary
    Effect of Supplement: This supplement amends the NADA to provide for a larger tablet containing 136.0 mg praziquantel, 136.0 mg pyrantel base as pyrantel pamoate and 680.4 mg febantel and the associated label changes.
  • Summary

    This supplemental application amends NADA 141-007, Drontal™ Plus Broad Spectrum Anthelmintic Tablets, by adding the tape-worm Echinococcus multilocularis claim to the label.

  • Summary

    Drontalâ¿¢ Plus Broad Spectrum Anthelmintic Tablets are indicated for the removal of the following intestinal parasites in dogs:

    Tapeworms (Dipylidium caninum, Taenia pisiformis, Echinococcus granulosus)

    Hookworms (Ancylostoma caninum, Incinaria stenocephala)

    Ascarids (Toxocara canis, Toxascaris leonina)

    Whipworms (Trichuris vulpis)

SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    This supplement provides for the addition of the following warning statement to the label: "Warning: Consider alternative therapy or use with caution in animals with pre-existing liver or kidney dysfunction."

SPL Packages

FDA page: Open in Animal Drugs @ FDA

SPL Packages

FDA page: Open in Animal Drugs @ FDA

SPL Packages

FDA page: Open in Animal Drugs @ FDA

SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    Rintal® Tabs Anthelmintic Tablets are indicated for the removal of the following nematode parasites: In Dogs and Puppies: Hookworms (Ancylosotoma caninum, Uncinaria stenocephala); Ascarids (Toxocara canis, Toxascaris leonina); Whipworms (Trichuris vulpis). In Cats and Kittens: Hookworms (ancylostoma tubaeforme); Ascarids (Toxocara cati).
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Usage

For removal of large strongyles (Strongylus vulgaris S. edentatus, S. equinus); ascarids (Parascaris equorum, sexually mature and immature); pinworms (Oxyuris equi-adult and 4th stage larva); and the various small strongyles in horses, foals, and ponies. For removal of ascarids (Parascaris equorum, adult and sexually immature), pinworms (Oxyuris equi-adult and 4th stage larvae), large strongyles (Strongylus vulgaris, S. edentatus, S. equinus), and the various small strongyles in horses, breeding stallions and mares, pregnant mares, foals, and ponies. For removal of hookworms (Ancylostoma caninum and Uncinaria stenocephala), whipworms (Trichuris vulpis), ascarids (Toxocara canis and Toxascaris leonina), and tapeworms (Dipylidium caninum and Taenia pisiformis).

Source: FDA Animal Drugs @ FDA • Reference

Contraindications

The paste may be administered on the base of the tongue or well mixed into a portion of the normal grain ration. For animals maintained on premises where reinfection is likely to occur, re-treatment may be necessary. For most effective results, retreat in 6 to 8 weeks. Not for use in horses intended for food. Consult your veterinarian for assistance in the diagnosis treatment, and control of parasitism. Administer by stomach tube or drench, or by mixing well into a portion of the normal grain ration. For animals maintained on premises where reinfection is likely to occur, re-treatment may be necessary. For most effective results, retreat in 6 to 8 weeks. Not for use in horses intended for food. Federal law restricts this drug to use by or on the order of a licensed veterinarian. Febantel suspension may be used in combination with trichlorfon oral liquid when combining 1 part febantel suspension with 5 parts trichlorfon liquid. Do not use in pregnant animals. Federal law restricts this drug to use by or on the order of a licensed veterinarian. Consider alternative therapy or use with caution in animals with pre-existing liver or kidney dysfunction.

Top Reported Reactions (openFDA)

De-duplicated reaction terms grouped by body system from FDA openFDA reports (not verified; does not prove causation).

Digestive
Vomiting (1) • Cat Partial anorexia (1) • Cat Loss of appetite (1) • Cat Decreased appetite (1) • Cat

Showing top 5 for Digestive.

Neurologic
Tiredness (1) • Dog

Showing top 5 for Neurologic.

Behavior
Behavioral disorder (1) • Dog

Showing top 5 for Behavior.

Effectiveness
Lack of efficacy - NOS (1) • Cat Lack of efficacy (endoparasite) - hookworm (1) • Dog

Showing top 5 for Effectiveness.

Other
Weight loss (1) • Cat Unclassifiable adverse event (1) • Cat Soft stool (1) • Dog Sickness (1) • Cat Pericardial effusion (1) • Dog
Show more (19)
Pancytopenia (1) • Dog Overdose (1) • Dog Other abnormal test result NOS (1) • Dog Not himself/herself (1) • Cat Not eating (1) • Cat Not drinking (1) • Cat Lying down (1) • Dog Increased respiratory rate (1) • Dog Inappropriate urination (1) • Dog Fluid in abdomen NOS (1) • Dog Febrile (1) • Dog Distension of abdomen (1) • Cat Discomfort NOS (1) • Dog Discoloured urine (1) • Dog Decreased activity (1) • Dog Death (1) • Dog Bloated stomach (1) • Dog Administration error NOS (1) • Cat Adipsia (1) • Cat

Showing top 5 for Other.

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Adverse Event Case Summaries (openFDA)

These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.

Dog, Newfoundland, Female, 10.66 year, 61.24 kilogram • Drug: MSK, Tablet, Oral, Dose: 2.25 tablet per animal • Reactions: Death • Outcome: Died

  • Report ID: USA-USFDACVM-2025-US-056128
  • Serious AE: Yes
  • Treated For AE: No
  • Sex: Female
  • Age: 10.66 Year
  • Weight: 61.240 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet
  • Dose: 2.25 tablet per animal
Reactions Reported:
Death
Outcomes: Died

Dog, Crossbred Canine/dog, Female, 3 month, 15.195 kilogram • Drug: MSK, Tablet, Oral • Reactions: Lack of efficacy (endoparasite) - hookworm, Other abnormal test result NOS • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-055641
  • Serious AE: No
  • Treated For AE: Yes
  • Sex: Female
  • Age: 3.00 Month
  • Weight: 15.195 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet
Reactions Reported:
Lack of efficacy (endoparasite) - hookworm Other abnormal test result NOS
Outcomes: Outcome Unknown

Dog, Retriever - Labrador, Female, 2.5 year, 26.21 kilogram • Drug: MSK, Tablet, Unknown • Reactions: Lack of efficacy (endoparasite) - hookworm, Other abnormal test result NOS • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-055796
  • Serious AE: No
  • Treated For AE: No
  • Sex: Female
  • Age: 2.50 Year
  • Weight: 26.210 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Tablet
Reactions Reported:
Lack of efficacy (endoparasite) - hookworm Other abnormal test result NOS
Outcomes: Outcome Unknown

Dog, Dog (unknown), Female, 13 week • Drug: MSK, Tablet, Oral • Reactions: Vomiting • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2025-US-055397
  • Serious AE: No
  • Treated For AE: No
  • Sex: Female
  • Age: 13.00 Week
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet
Reactions Reported:
Vomiting
Outcomes: Recovered/Normal

Dog, Greyhound - Italian, Female, 1.33 year, 4.76 kilogram • Drug: MSK, Tablet, Oral, Dose: 1.50 tablet per animal, Frequency: 2 per week • Reactions: Lying down, Behavioral disorder (unspecified) • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-055883
  • Serious AE: No
  • Treated For AE: No
  • Sex: Female
  • Age: 1.33 Year
  • Weight: 4.760 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet
  • Dose: 1.50 tablet per animal
  • Frequency: 2 per week
Reactions Reported:
Lying down Behavioral disorder (unspecified)
Outcomes: Ongoing

Dog, Shepherd Dog - Australian, Female, 14.25 year, 22.67 kilogram • Drug: MSK, Tablet, Oral, Dose: 2 tablet per animal • Reactions: Tiredness (lethargy), Increased respiratory rate, Fluid in abdomen NOS, Pericardial effusion, Death • Outcome: Died

  • Report ID: USA-USFDACVM-2025-US-053307
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 14.25 Year
  • Weight: 22.670 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet
  • Dose: 2 tablet per animal
Reactions Reported:
Tiredness (lethargy) Increased respiratory rate Fluid in abdomen NOS Pericardial effusion Death
Outcomes: Died

Dog, Bulldog - French, Male, 8 year, 13.88 kilogram • Drug: MSK, Tablet, Oral, Dose: 1.50 tablet per animal, Frequency: 1 per day • Reactions: Soft stool, Vomiting, Loss of appetite, Inappropriate urination, Discomfort NOS… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-054237
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 8.00 Year
  • Weight: 13.880 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet
  • Dose: 1.50 tablet per animal
  • Frequency: 1 per day
Reactions Reported:
Soft stool Vomiting Loss of appetite Inappropriate urination Discomfort NOS Febrile Discoloured urine Pancytopenia
Outcomes: Ongoing

Dog, Pit Bull, Male, 10 week, 3.175 kilogram • Drug: MSK, Tablet, Oral, Dose: 3 tablet per animal • Reactions: Bloated stomach, Decreased activity, Overdose • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2025-US-054129
  • Serious AE: No
  • Treated For AE: No
  • Sex: Male
  • Age: 10.00 Week
  • Weight: 3.175 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet
  • Dose: 3 tablet per animal
Reactions Reported:
Bloated stomach Decreased activity Overdose
Outcomes: Recovered/Normal

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Overdose Information

No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.

Storage & Handling

No approved storage guidance is linked yet for this ingredient. Use manufacturer packaging and veterinary guidance for handling/storage.

Share Your Thoughts

Let others know your experience or advice regarding this medication.

This medication has not been reviewed by a veterinarian yet.