Medication reference facts with explicit FDA-approval, off-label, source-limited, and safety context. Roxee does not sell, prescribe, or dispense medications.
BothReference completeFDA data linkedRx requiredLiquid (Solution)Multiple FDA sponsors
Official label facts
Owner quick guide first
Merged from the current Roxee medication system with field-level provenance, freshness, and completeness tracking.
Dexmedetomidine Hydrochloride
For use as a sedative and analgesic to facilitate clinical examinations, clinical procedures, minor surgical procedures, and minor dental procedures. For use as a preanesthetic to general anesthesia. For use as a sedative and analgesic in dogs to facilitate clinical examinations, clinical procedures, minor surgical procedures, and minor dental procedures. Species commonly shown: Both, Dog, Cat.
For use as a sedative and analgesic to facilitate clinical examinations, clinical procedures, minor surgical procedures, and minor dental procedures. For use as a preanesthetic to general anesthesia. For use as a sedative and analgesic in dogs to facilitate clinical examinations, clinical procedures, minor surgical procedures, and minor dental procedures.
Warnings / Contraindications
Federal law restricts this drug to use by or on the order of a licensed veterinarian. Do not use DEXDOMITOR in dogs or cats with cardiovascular disease, respiratory disorders, liver or kidney diseases, or in conditions of shock, severe debilitation, or stress due to extreme heat, cold or fatigue.
Federal law restricts this drug to use by or on the order of a licensed veterinarian. Do not use DEXDOMITOR in dogs or cats with cardiovascular disease, respiratory disorders, liver or kidney diseases, or in conditions of shock, severe debilitation, or stress due to extreme heat, cold or fatigue.
Side Effects
Top reported reactions (openFDA): Lack of efficacy - NOS, Bradycardia, INEFFECTIVE, SEDATION, Vomiting, Sedation, Lethargy (see also Central nervous system depression in 'Neurological').
Start here first for the safest next-step summary before the deeper medication detail.
Used for:
For use as a sedative and analgesic to facilitate clinical examinations, clinical procedures, minor surgical procedures, and minor dental procedures.
Dosing note:
Exact dosing depends on your pet's species, weight, and health status. Use your veterinarian's instructions for the exact dose and schedule.
What to watch for:
Do not use DEXDOMITOR in dogs or cats with cardiovascular disease, respiratory disorders, liver or kidney diseases, or in conditions of shock, severe debilitation, or stress due to extreme heat, cold or fatigue
wobbly/unsteady walking (1 reports)
Loss of appetite (1 reports)
Bladder distension (1 reports)
When to call the vet:
Repeated vomiting or diarrhea.
Severe lethargy (hard to wake, very low energy).
Collapse or fainting.
Trouble breathing.
Facial swelling or hives.
Blood in vomit or stool.
Regulatory restrictions are shown in Vet View.
What to tell or ask your vet today:
Is this medicine the right fit for my pet’s current symptoms?
Which warning signs mean I should call back right away?
How should I handle missed doses or refusal to take the medicine?
A source-aware map of what to know, what is uncertain, and what to verify with your veterinarian.
Source Backed Signals
What to know
Evidence-backed contextLimited
Roxee has limited cited overview evidence for Dexmedetomidine Hydrochloride; use the official documents and your veterinarian's instructions for product-specific decisions.
Source: openFDA case USA-USFDACVM-2026-US-014066
Safety signal coverageReported signals
32 tracked reaction signals; 32 reported cases; 22 serious reports; 2 species groups. These are reporting and label-derived signals for interpretation with a veterinarian.
Source: openFDA case USA-USFDACVM-2026-US-014066
Interpretation guardrailNot causation
Adverse-event reports help form a watch list, but they do not prove the medication caused the reaction and they are not a risk ranking between medications.
Evidence tension
Stronger signalLabel / review
Official labels, package inserts, and reviewed summaries carry more weight than isolated reports.
Source: openFDA case USA-USFDACVM-2026-US-014066
Weaker signalReported data
Case reports and openFDA terms are useful for pattern awareness, but they are incomplete, can include multiple exposures, and do not estimate an individual pet's probability of harm.
Domestic Shorthair (2), Pug (1), ['Mastiff (unspecified)', 'Crossbred Canine/dog'] (1), Ragdoll (1). These are report metadata, not proof that a breed is at higher risk.
What your vet may verify
Fit for this patientVet check
Verify whether Dexmedetomidine Hydrochloride fits the pet's species, current diagnosis, age, weight, organ status, pregnancy/lactation status, and concurrent medications.
Evidence limitationsEvidence review
Separate label-backed warnings from adverse-event reports and owner observations before changing the plan.
What to watch next
Watch listOwner-safe
Do not use DEXDOMITOR in dogs or cats with cardiovascular disease, respiratory disorders, liver or k, wobbly/unsteady walking, Loss of appetite, Bladder distension
Call sooner ifEscalation
Repeated vomiting or diarrhea. Severe lethargy (hard to wake, very low energy). Collapse or fainting.
Bottom line: Use this Dexmedetomidine Hydrochloride brief as a structured watch list and source map, not as a reason to start, stop, or change treatment without your veterinarian.
Do not use DEXDOMITOR in dogs or cats with cardiovascular disease, respiratory disorders, liver or kidney diseases, or in conditions of shock, severe debilitation, or stress due to extreme heat, cold or fatigue
Federal law restricts this drug to use by or on the order of a licensed veterinarian. Do not use DEXDOMITOR in dogs or cats with cardiovascular disease, respiratory disorders, liver or kidney diseases, or in conditions of shock, severe debilitation, or stress due to extreme heat, cold or fatigue.
High: Federal law restricts this drug to use by or on the order of a licensed veterinarian. Do not use DEXDOMITOR in dogs or cats with cardiovascular disease, respiratory disorders, liver or kidney diseases, or in conditions of shock, severe debilitation, or stress due to extreme heat, cold or fatigue.
HypersalivationTachypnoeaAbnormal radiograph findingHypothermiaHyperactivityNot eatingLethargy (see also Central nervous system depression in Neurological)Hiding
Not eatingVomitingCardiac enlargementSplenomegalyAbnormal ultrasound findingHaematuriaPyuriaNon-regenerative anaemiaDecreased haematocritHypokalaemiaBladder distensionDehydrationElevated creatinineNot urinatingIntentional misuseUrinary tract disorder NOS
Body systems
OtherDigestive
Outcomes
Ongoing
USA-USFDACVM-2025-US-067945
Received 2025-11-12
· MSK
· MSK
Serious
Species
Cat
Breed
Domestic Longhair
Size / weight
10-24 lb (5.7 Kilogram)
Age
8+ years (14 Year)
Sex
Male Neutered
Region
USA
Reactions
Hind limb paresisHidingNot eatingNot drinkingDry mucous membraneWeak pulseHyperthermiaDepressionLethargy (see also Central nervous system depression in Neurological)
Body systems
OtherNeurologic
Outcomes
Ongoing
USA-USFDACVM-2025-US-065439
Received 2025-11-04
· MSK
· MSK
Serious
Species
Dog
Breed
['Retriever - Labrador', 'Dog (unknown)']
Size / weight
25-49 lb (18.144 Kilogram)
Age
1-3 years (3 Year)
Sex
Female Unknown
Region
USA
Reactions
VocalisationPain NOSLimb non-weight bearingNot eatingNot drinkingBiting -aggression (see also Skin and appendages disorders)Stiffness NOSReluctant to moveAbnormal posture NOS
Body systems
OtherBehavior
Outcomes
Ongoing
Tap or hover a reaction to see what it means in plain language.
Tracked signals
32
Reported cases
32
Serious reports
22
Species represented
2
Grouped by Body System
Digestive (1)
· Loss of appetite
Skin & allergy (3)
· Hair loss at application site, Application site hair loss, Alopecia local
Neurologic (1)
· Unsteady walking (ataxia)
Behavior (4)
· Biting -aggression, Behavioral disorder (unspecified), Anxiety
Other (23)
· Bladder distension, Bilirubinuria, Basophilia
Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.
Sponsor
Parnell Technologies Pty. Ltd.
ANADA
200-699
Status
RX
Form
Injectable Solution
Route
Intravenous, Intramuscular
Species
Dog • Cat
Composition / specifications
0.5 mg/mL
Dogs
Indication
For use as a sedative and analgesic to facilitate clinical examinations, clinical procedures, minor surgical procedures, and minor dental procedures.
Dosage
Administer 375 micrograms (mcg) per square meter (/m2) of body surface area by intravenous injection or 500 mcg/m2 of body surface area by intramuscular injection.
Indication
For use as a preanesthetic to general anesthesia.
Dosage
Administer 125 mcg/m2 of body surface area or 375 mcg/m2 of body surface area by intramuscular injection.
Cats
Indication
For use as a sedative and analgesic to facilitate clinical examinations, clinical procedures, minor surgical procedures, and minor dental procedures; and as a preanesthetic to general anesthesia.
Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.
Sponsor
Felix Pharmaceuticals Pvt. Ltd.
ANADA
200-824
Status
RX
Form
Sterile Injectable Solution
Route
Intravenous, Intramuscular
Composition / specifications
0.5 mg/mL
Dogs
Indication
For use as a sedative and analgesic to facilitate clinical examinations, clinical procedures, minor surgical procedures, and minor dental procedures.
Dosage
Administer 375 micrograms (µg) per square meter (/m2) of body surface area by intravenous injection or 500 µg/m2 of body surface area by intramuscular injection.
Indication
For use as a preanesthetic to general anesthesia.
Dosage
Administer 125 µg/m2 of body surface area or 375 µg/m2 of body surface area by intramuscular injection.
Cats
Indication
For use as a sedative and analgesic to facilitate clinical examinations, clinical procedures, minor surgical procedures, and minor dental procedures; and as a preanesthetic to general anesthesia.
Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.
Sponsor
Cronus Pharma Specialities India Private Ltd.
ANADA
200-752
Status
RX
Form
Sterile Injectable Solution
Route
Intramuscular, Intravenous
Species
Dog • Cat
Composition / specifications
0.5 mg/mL
Dogs
Indication
For use as a sedative and analgesic to facilitate clinical examinations, clinical procedures, minor surgical procedures, and minor dental procedures. It is also indicated for use as a preanesthetic to general anesthesia.
Dosage
Sedation and Analgesia: 500 mcg/m2 intramuscularly (IM) or 375 mcg/m2 intravenously (IV). Preanesthesia: 125 or 375 mcg/m2 IM.
Cats
Indication
For use as a sedative and analgesic to facilitate clinical examinations, clinical procedures, minor surgical procedures, and minor dental procedures. It is also indicated for use as a preanesthetic to general anesthesia.
Dosage
Sedation, Analgesia and Preanesthesia: 40 mcg/kg IM.
Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.
Sponsor
ZyVet Animal Health, Inc.
ANADA
200-735
Status
RX
Form
Injectable Solution
Route
Intravenous, Intramuscular
Species
Dog • Cat
Composition / specifications
0.5 mg/mL
Dogs
Indication
For use as a sedative and analgesic to facilitate clinical examinations, clinical procedures, minor surgical procedures, and minor dental procedures. It is also indicated for use as a preanesthetic to general anesthesia.
Dosage
Sedation and Analgesia: 500 mcg/m2 intramuscularly (IM) or 375 mcg/m2 intravenously (IV). Preanesthesia: 125 or 375 mcg/m2 IM.
Cats
Indication
For use as a sedative and analgesic to facilitate clinical examinations, clinical procedures, minor surgical procedures, and minor dental procedures. It is also indicated for use as a preanesthetic to general anesthesia.
Dosage
Sedation, Analgesia and Preanesthesia: 40 mcg/kg intramuscularly (IM)
Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.
Sponsor
Dechra Veterinary Products LLC
ANADA
200-573
Status
RX
Form
Sterile Solution
Route
Intramuscular, Intravenous
Species
Dog • Cat
Composition / specifications
0.5 mg/mL
<strong>Dogs</strong>
Dosage
For sedative and analgesic administer 375 mcg/m2 by intravenous (IV) injection or 500 mcg/m2 by intramuscular (IM) injection; for preanesthesia administer 125 or 375 mcg/m2 by IM injection
<strong>Cats</strong>
Indication
For use as a sedative and analgesic in dogs and cats to facilitate clinical examinations, clinical procedures, minor surgical procedures, and minor dental procedures. Dexmedetomidine HCl is also indicated for use as a preanesthetic to general anesthesia in dogs and cats
Dosage
For sedation, analgesia, or preanesthesia administer 40 mcg/kg IM
Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.
Sponsor
Orion Corp.
NADA
141-267
Status
RX
Form
Liquid (Solution)
Route
Intravenous, Intramuscular
Species
Dog • Cat
Composition / specifications
Each mL contains 0.5 mg dexmedetomidine hydrochloride
Cats
Indication
For use as a sedative and analgesic to facilitate clinical examinations, clinical procedures, minor surgical procedures, and minor dental procedures.
Dosage
40 mcg/kg by intramuscular (IM) injection.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian. Do not use DEXDOMITOR in dogs or cats with cardiovascular disease,
respiratory disorders, liver or kidney diseases, or in conditions of shock, severe debilitation, or stress
due to extreme heat, cold or fatigue.
Indication
For use as a preanesthetic to general anesthesia.
Dosage
40 mcg/kg by intramuscular (IM) injection.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian. Do not use DEXDOMITOR in dogs or cats with cardiovascular disease,
respiratory disorders, liver or kidney diseases, or in conditions of shock, severe debilitation, or stress
due to extreme heat, cold or fatigue.
Dogs
Indication
For use as a sedative and analgesic in dogs to facilitate clinical examinations, clinical procedures, minor surgical procedures, and minor dental procedures.
Dosage
Administer 500 mcg/m2 intramuscularly (IM) or 375 mcg/m2 of body surface area by intravenous (IV) injection. Note that the mcg/kg dosage decreases as body weight increases.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian. Do not use DEXDOMITOR in dogs or cats with cardiovascular disease,
respiratory disorders, liver or kidney diseases, or in conditions of shock, severe debilitation, or stress
due to extreme heat, cold or fatigue.
Indication
For use as a preanesthetic to general anesthesia.
Dosage
Administer 125 mcg/m2 of body surface area or 375 mcg/m2 of body surface area by intramuscular injection. Note that the mcg/kg dosage decreases as body weight increases.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian. Do not use DEXDOMITOR in dogs or cats with cardiovascular disease,
respiratory disorders, liver or kidney diseases, or in conditions of shock, severe debilitation, or stress
due to extreme heat, cold or fatigue.
FOI Summary oA 200-699 Approved March 11, 2021.pdf
Diagnosis-code mappings are not available for this medication yet.
Counseling and Monitoring Highlights
Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.
Owner-facing counseling points
Federal law restricts this drug to use by or on the order of a licensed veterinarian. Do not use DEXDOMITOR in dogs or cats with cardiovascular disease, respiratory disorders, liver or kidney diseases, or in conditions of shock, severe debilitation, or stress due to extreme heat, cold or fatigue. (Contraindication, High)
Top reaction signals
Unsteady walking (ataxia) (1)Loss of appetite (1)Bladder distension (1)Biting -aggression (1)Bilirubinuria (1)Behavioral disorder (unspecified) (1)Basophilia (1)Balance problem (1)
Identifiers & Packages
Normalized identifiers (NDC/NADA/ANADA) and package metadata from regulator listings.
UCM475135.pdf • FOI summary • Official • May 17, 2021
FDA FOI summary for application 141456
ucm062316.pdf • FOI summary • Official • June 1, 2016
FDA FOI summary for application 141267
ucm062318.pdf • FOI summary • Official • June 1, 2016
FDA FOI summary for application 141267
UCM504535.pdf • FOI summary • Official • June 1, 2016
FDA FOI summary for application 141267
Data Sources & Change Log
Every non-trivial field is expected to include provenance and update timestamps.
Official 125Clinical 1Manufacturer 0Marketing 0
Current Field Facts
side_effects: Top reported reactions (openFDA): Lack of efficacy - NOS, Bradycardia, INEFFECTIVE, SEDATION, Vomiting, Sedation, Lethargy (see also Central nervous system dep… (Clinical, 2026-04-11)
contraindications: Federal law restricts this drug to use by or on the order of a licensed veterinarian. Do not use DEXDOMITOR in dogs or cats with cardiovascular disease, respir… (Official, 2026-04-12)
contraindications: Federal law restricts this drug to use by or on the order of a licensed veterinarian. Do not use DEXDOMITOR in dogs or cats with cardiovascular disease, respir… (Official, 2026-04-11)
contraindications: Federal law restricts this drug to use by or on the order of a licensed veterinarian. Do not use DEXDOMITOR in dogs or cats with cardiovascular disease, respir… (Official, 2026-02-12)
indications: DEXDOMITOR is indicated for use as a sedative and analgesic in dogs to facilitate clinical examinations, clinical procedures, minor surgical procedures, and mi… (Official, 2026-08-06)
indications: DEXDOMITOR is indicated for use as a sedative and analgesic in dogs to facilitate clinical examinations, clinical procedures, minor surgical procedures, and mi… (Official, 2026-08-05)
indications: DEXDOMITOR is indicated for use as a sedative and analgesic in dogs to facilitate clinical examinations, clinical procedures, minor surgical procedures, and mi… (Official, 2026-08-04)
indications: DEXDOMITOR is indicated for use as a sedative and analgesic in dogs to facilitate clinical examinations, clinical procedures, minor surgical procedures, and mi… (Official, 2026-08-03)
indications: DEXDOMITOR is indicated for use as a sedative and analgesic in dogs to facilitate clinical examinations, clinical procedures, minor surgical procedures, and mi… (Official, 2026-08-02)
indications: DEXDOMITOR is indicated for use as a sedative and analgesic in dogs to facilitate clinical examinations, clinical procedures, minor surgical procedures, and mi… (Official, 2026-08-01)
indications: DEXDOMITOR is indicated for use as a sedative and analgesic in dogs to facilitate clinical examinations, clinical procedures, minor surgical procedures, and mi… (Official, 2026-07-31)
indications: DEXDOMITOR is indicated for use as a sedative and analgesic in dogs to facilitate clinical examinations, clinical procedures, minor surgical procedures, and mi… (Official, 2026-07-30)
indications: DEXDOMITOR is indicated for use as a sedative and analgesic in dogs to facilitate clinical examinations, clinical procedures, minor surgical procedures, and mi… (Official, 2026-07-29)
indications: DEXDOMITOR is indicated for use as a sedative and analgesic in dogs to facilitate clinical examinations, clinical procedures, minor surgical procedures, and mi… (Official, 2026-07-28)
indications: DEXDOMITOR is indicated for use as a sedative and analgesic in dogs to facilitate clinical examinations, clinical procedures, minor surgical procedures, and mi… (Official, 2026-07-27)
indications: DEXDOMITOR is indicated for use as a sedative and analgesic in dogs to facilitate clinical examinations, clinical procedures, minor surgical procedures, and mi… (Official, 2026-07-26)
indications: DEXDOMITOR is indicated for use as a sedative and analgesic in dogs to facilitate clinical examinations, clinical procedures, minor surgical procedures, and mi… (Official, 2026-07-25)
indications: DEXDOMITOR is indicated for use as a sedative and analgesic in dogs to facilitate clinical examinations, clinical procedures, minor surgical procedures, and mi… (Official, 2026-07-25)
indications: DEXDOMITOR is indicated for use as a sedative and analgesic in dogs to facilitate clinical examinations, clinical procedures, minor surgical procedures, and mi… (Official, 2026-07-22)
indications: DEXDOMITOR is indicated for use as a sedative and analgesic in dogs to facilitate clinical examinations, clinical procedures, minor surgical procedures, and mi… (Official, 2026-07-22)
Recent Revisions
side_effects updated 2026-04-12 10:05 by etl_backfill • Backfilled from existing medication fields
contraindications updated 2026-04-12 10:05 by etl_backfill • Backfilled from existing medication fields
usage updated 2026-04-12 10:05 by etl_backfill • Backfilled from existing medication fields
side_effects updated 2026-04-11 10:05 by etl_backfill • Backfilled from existing medication fields
contraindications updated 2026-04-11 10:05 by etl_backfill • Backfilled from existing medication fields
usage updated 2026-04-11 10:05 by etl_backfill • Backfilled from existing medication fields
side_effects updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields
contraindications updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields
usage updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields
FDA Products & Applications (Animal Drugs @ FDA)
Official sponsor/proprietary-name/application-status records linked by active ingredient.
Data source: FDA Animal Drugs @ FDA (public search export).
What It's For (FDA Label Highlights)
Extracted from FDA Animal Drugs @ FDA product labeling. Always confirm details with your veterinarian.
Species: Dog • Cat
Composition / specifications
0.5 mg/mL
Dogs
Indication
For use as a sedative and analgesic to facilitate clinical examinations, clinical procedures, minor surgical procedures, and minor dental procedures.
Dosage
Administer 375 micrograms (mcg) per square meter (/m2) of body surface area by intravenous injection or 500 mcg/m2 of body surface area by intramuscular injection.
Limitations
Indication
For use as a preanesthetic to general anesthesia.
Dosage
Administer 125 mcg/m2 of body surface area or 375 mcg/m2 of body surface area by intramuscular injection.
Limitations
Cats
Indication
For use as a sedative and analgesic to facilitate clinical examinations, clinical procedures, minor surgical procedures, and minor dental procedures; and as a preanesthetic to general anesthesia.
For use as a sedative and analgesic to facilitate clinical examinations, clinical procedures, minor surgical procedures, and minor dental procedures.
Dosage
Administer 375 micrograms (µg) per square meter (/m2) of body surface area by intravenous injection or 500 µg/m2 of body surface area by intramuscular injection.
Limitations
Indication
For use as a preanesthetic to general anesthesia.
Dosage
Administer 125 µg/m2 of body surface area or 375 µg/m2 of body surface area by intramuscular injection.
Limitations
Cats
Indication
For use as a sedative and analgesic to facilitate clinical examinations, clinical procedures, minor surgical procedures, and minor dental procedures; and as a preanesthetic to general anesthesia.
For use as a sedative and analgesic to facilitate clinical examinations, clinical procedures, minor surgical procedures, and minor dental procedures. It is also indicated for use as a preanesthetic to general anesthesia.
Dosage
Sedation and Analgesia: 500 mcg/m2 intramuscularly (IM) or 375 mcg/m2 intravenously (IV). Preanesthesia: 125 or 375 mcg/m2 IM.
Limitations
Cats
Indication
For use as a sedative and analgesic to facilitate clinical examinations, clinical procedures, minor surgical procedures, and minor dental procedures. It is also indicated for use as a preanesthetic to general anesthesia.
Dosage
Sedation, Analgesia and Preanesthesia: 40 mcg/kg IM.
For use as a sedative and analgesic to facilitate clinical examinations, clinical procedures, minor surgical procedures, and minor dental procedures. It is also indicated for use as a preanesthetic to general anesthesia.
Dosage
Sedation and Analgesia: 500 mcg/m2 intramuscularly (IM) or 375 mcg/m2 intravenously (IV). Preanesthesia: 125 or 375 mcg/m2 IM.
Limitations
Cats
Indication
For use as a sedative and analgesic to facilitate clinical examinations, clinical procedures, minor surgical procedures, and minor dental procedures. It is also indicated for use as a preanesthetic to general anesthesia.
Dosage
Sedation, Analgesia and Preanesthesia: 40 mcg/kg intramuscularly (IM)
For sedative and analgesic administer 375 mcg/m2 by intravenous (IV) injection or 500 mcg/m2 by intramuscular (IM) injection; for preanesthesia administer 125 or 375 mcg/m2 by IM injection
Limitations
<strong>Cats</strong>
Indication
For use as a sedative and analgesic in dogs and cats to facilitate clinical examinations, clinical procedures, minor surgical procedures, and minor dental procedures. Dexmedetomidine HCl is also indicated for use as a preanesthetic to general anesthesia in dogs and cats
Dosage
For sedation, analgesia, or preanesthesia administer 40 mcg/kg IM
Each mL contains 0.5 mg dexmedetomidine hydrochloride
Cats
Indication
For use as a sedative and analgesic to facilitate clinical examinations, clinical procedures, minor surgical procedures, and minor dental procedures.
Dosage
40 mcg/kg by intramuscular (IM) injection.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian. Do not use DEXDOMITOR in dogs or cats with cardiovascular disease,
respiratory disorders, liver or kidney diseases, or in conditions of shock, severe debilitation, or stress
due to extreme heat, cold or fatigue.
Indication
For use as a preanesthetic to general anesthesia.
Dosage
40 mcg/kg by intramuscular (IM) injection.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian. Do not use DEXDOMITOR in dogs or cats with cardiovascular disease,
respiratory disorders, liver or kidney diseases, or in conditions of shock, severe debilitation, or stress
due to extreme heat, cold or fatigue.
Dogs
Indication
For use as a sedative and analgesic in dogs to facilitate clinical examinations, clinical procedures, minor surgical procedures, and minor dental procedures.
Dosage
Administer 500 mcg/m2 intramuscularly (IM) or 375 mcg/m2 of body surface area by intravenous (IV) injection. Note that the mcg/kg dosage decreases as body weight increases.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian. Do not use DEXDOMITOR in dogs or cats with cardiovascular disease,
respiratory disorders, liver or kidney diseases, or in conditions of shock, severe debilitation, or stress
due to extreme heat, cold or fatigue.
Indication
For use as a preanesthetic to general anesthesia.
Dosage
Administer 125 mcg/m2 of body surface area or 375 mcg/m2 of body surface area by intramuscular injection. Note that the mcg/kg dosage decreases as body weight increases.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian. Do not use DEXDOMITOR in dogs or cats with cardiovascular disease,
respiratory disorders, liver or kidney diseases, or in conditions of shock, severe debilitation, or stress
due to extreme heat, cold or fatigue.
For use as a sedative and analgesic to facilitate clinical examinations, clinical procedures, minor surgical procedures, and minor dental procedures. For use as a preanesthetic to general anesthesia. For use as a sedative and analgesic in dogs to facilitate clinical examinations, clinical procedures, minor surgical procedures, and minor dental procedures.
Federal law restricts this drug to use by or on the order of a licensed veterinarian. Do not use DEXDOMITOR in dogs or cats with cardiovascular disease, respiratory disorders, liver or kidney diseases, or in conditions of shock, severe debilitation, or stress due to extreme heat, cold or fatigue.
Top Reported Reactions (openFDA)
De-duplicated reaction terms grouped by body system from FDA openFDA reports (not verified; does not prove causation).
Digestive
Loss of appetite (1) • Cat
Showing top 5 for Digestive.
Skin & allergy
Hair loss at application site (1) • Cat
Application site hair loss (1) • Cat
Alopecia local (1) • Dog
Data source: FDA openFDA Animal & Veterinary adverse event reports.
Overdose Information
No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.
Storage & Handling
No approved storage guidance is linked yet for this ingredient. Use manufacturer packaging and veterinary guidance for handling/storage.
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Let others know your experience or advice regarding this medication.
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This medication has not been reviewed by a veterinarian yet.
Medical Disclaimer: The medication details provided on Roxee are for informational purposes only and are not a substitute for professional veterinary advice. Always consult your veterinarian about your pet's specific needs.