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Imidacloprid, Moxidectin

Detailed information about Imidacloprid, Moxidectin

Official label facts Owner quick guide first Marketing clearly labeled
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Reviewed / Updated / Sources

Reviewed: Not available

Updated: February 12, 2026, 10:44 PM UTC

Sources:

Pet Owner Quick Guide

Start here first for the simple next-step summary.

Used for:

Your vet decides this. Here's what owners typically ask/watch for.

What to watch for:

  • Lack of efficacy - heartworm (1 reports)
  • Increased percentage reticulocytes (1 reports)
  • Hair change (1 reports)

When to call the vet:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
  • Facial swelling or hives.
  • Blood in vomit or stool.

What to ask your vet today:

  • Is this medicine the right fit for my pet’s current symptoms?
  • Which warning signs mean I should call back right away?
  • How should I handle missed doses or refusal to take the medicine?
Safety & side effects

What to watch:

  • Lack of efficacy - heartworm
  • Increased percentage reticulocytes
  • Hair change

Most reported reactions:

  • Lack of efficacy (endoparasite) - heartworm (1 reports)
  • Increased percentage reticulocytes (1 reports)
  • Hair change (1 reports)

When to call your vet:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
Talk to a Vet / Find a Vet Near You Start Symptom Intake

Data freshness: source data appears current.

Latest refresh: Mar 21, 2026, 10:01 a.m.

Data freshness
  • Medication catalog: Source Roxee | Refreshed Feb 12, 2026, 10:44 PM UTC
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed Mar 21, 2026, 10:01 AM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
  • openFDA reaction terms: Source FDA openFDA | Refreshed Feb 9, 2026, 3:13 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Feb 9, 2026, 3:20 AM UTC
Image coming soon
Imidacloprid, Moxidectin

Imidacloprid, Moxidectin

Drug type: Generic ingredient • Generic profile • No FDA branded products linked

Species: Both

Manufacturer: Not available (source)

Quick Facts

Official label facts first, then secondary summaries. Marketing content is separated below.

Species: Both
Manufacturer: Not available
Identifiers:
NDC Package: 51072-100-01 NDC Package: 51072-100-02 NDC Package: 51072-100-03 NDC Package: 51072-100-04 NDC Package: 51072-100-05 NDC Package: 51072-101-01 NDC Package: 51072-101-02 NDC Package: 51072-101-03 NDC Package: 58198-0048-1 NDC Package: 58198-0048-3 NDC Package: 58198-0049-1 NDC Package: 58198-0049-3 NDC Package: 58198-0050-1 NDC Package: 58198-0050-3 NDC Package: 58198-0051-1 NDC Package: 58198-0051-3 NDC Package: 58198-0052-1 NDC Package: 58198-0052-2 NDC Package: 58198-0053-1 NDC Package: 58198-0053-3

Adverse Reactions

Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.

Tap or hover a reaction to see what it means in plain language.

Tracked signals
20
Reported cases
14
Serious reports
4
Species represented
2
Grouped by Body System
Digestive (3) · Vomiting, Diarrhea, Drooling Skin & allergy (1) · Hair loss at application site Neurologic (1) · Lethargy (see also Central nervous system depression in Neurological) Behavior (1) · Behavioral disorder (unspecified) Effectiveness (5) · Lack of efficacy - NOS, Lack of efficacy (endoparasite) - hookworm, Lack of efficacy (endoparasite) - heartworm Other (9) · Skin scab, Increased percentage reticulocytes, Hypersensitivity reaction
Most Reported Reactions
Reaction Body system Cases Species Serious cases
Effectiveness 1 Dog 1
Other 1 Dog 1
Other 1 Dog 1
Other 1 Dog 1
Digestive 1 Dog 0
Other 1 Cat 0
Effectiveness 1 Cat 0
Effectiveness 1 Dog 0

Species coverage: Dog (10) Cat (10)

View detailed reaction table
Reaction Body system Species Seriousness Frequency Reports
Digestive Dog Non-serious - 1
Other Cat Non-serious - 1
Effectiveness Cat Non-serious - 1
Effectiveness Dog Non-serious - 1
Effectiveness Dog Serious - 1
Effectiveness Cat Non-serious - 1
Other Dog Serious - 1
Other Cat Non-serious - 1
Skin & allergy Cat Non-serious - 1
Other Dog Serious - 1
Digestive Dog Non-serious - 1
Other Dog Serious - 1
Other Cat Non-serious - 1
Other Cat Non-serious - 1
Other Dog Unknown - -
Neurologic Dog Unknown - -
Effectiveness Cat Unknown - -
Digestive Cat Unknown - -
Other Dog Unknown - -
Behavior Cat Unknown - -
Source metadata:
Veterinary reference (advanced)

Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.

At a Glance

Quick facts and links to official labeling and safety signals.

Data freshness
  • Medication catalog: Source Roxee | Refreshed Feb 12, 2026, 10:44 PM UTC
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed Mar 21, 2026, 10:01 AM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
  • openFDA reaction terms: Source FDA openFDA | Refreshed Feb 9, 2026, 3:13 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Feb 9, 2026, 3:20 AM UTC
Official (FDA)
Identity: Generic ingredient • No FDA branded products linked
No official FDA brand rows linked yet for this ingredient.
Case-reported brands (openFDA): MSK
Catalog species: Both
Safety (openFDA)
Top reactions: Dog 8 • Cat 8 • View
Case summaries: 10 (showing 8) • View
openFDA reports are unverified and do not prove causation.
Diagnosis Codes

Diagnosis-code mappings are not available for this medication yet.

Counseling and Monitoring Highlights

Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.

Top reaction signals
Lack of efficacy (endoparasite) - heartworm (1) Increased percentage reticulocytes (1) Hair change (1) Basophilia (1) Vomiting (1) Skin scab (1) Lack of efficacy - NOS (1) Lack of efficacy (endoparasite) - hookworm (1)

Identifiers & Packages

Normalized identifiers (NDC/NADA/ANADA) and package metadata from regulator listings.

Identifiers
NDC Package: 51072-100-01 NDC Package: 51072-100-02 NDC Package: 51072-100-03 NDC Package: 51072-100-04 NDC Package: 51072-100-05 NDC Package: 51072-101-01 NDC Package: 51072-101-02 NDC Package: 51072-101-03 NDC Package: 58198-0048-1 NDC Package: 58198-0048-3 NDC Package: 58198-0049-1 NDC Package: 58198-0049-3 NDC Package: 58198-0050-1 NDC Package: 58198-0050-3 NDC Package: 58198-0051-1 NDC Package: 58198-0051-3 NDC Package: 58198-0052-1 NDC Package: 58198-0052-2 NDC Package: 58198-0053-1 NDC Package: 58198-0053-3 NDC Package: 58198-0054-1 NDC Package: 58198-0054-3 NDC Package: 58198-0055-1 NDC Package: 58198-0055-3
Package NDC Product NDC Form / Route Status
51072-100-01 51072 -
51072-100-02 51072 -
51072-100-03 51072 -
51072-100-04 51072 -
51072-100-05 51072 -
51072-101-01 51072 -
51072-101-02 51072 -
51072-101-03 51072 -
58198-0048-1 58198 -
58198-0048-3 58198 -
58198-0049-1 58198 -
58198-0049-3 58198 -
58198-0050-1 58198 -
58198-0050-3 58198 -
58198-0051-1 58198 -
58198-0051-3 58198 -
58198-0052-1 58198 -
58198-0052-2 58198 -
58198-0053-1 58198 -
58198-0053-3 58198 -

Data Sources & Change Log

Every non-trivial field is expected to include provenance and update timestamps.

Official 1 Clinical 0 Manufacturer 0 Marketing 0
Current Field Facts
  • side_effects: Top reported reactions (openFDA): Lack of efficacy (endoparasite) - heartworm, Lack of efficacy (ectoparasite) - flea, Lack of efficacy (endoparasite) - hookwo… (Official, 2026-02-12)
Recent Revisions
  • side_effects updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields

Top Reported Reactions (openFDA)

De-duplicated reaction terms grouped by body system from FDA openFDA reports (not verified; does not prove causation).

Digestive
Vomiting (1) • Dog Diarrhea (1) • Dog Drooling • Cat

Showing top 5 for Digestive.

Skin & allergy
Hair loss at application site (1) • Cat

Showing top 5 for Skin & allergy.

Neurologic
Tiredness (lethargy) • Dog

Showing top 5 for Neurologic.

Behavior
Behavioral disorder • Cat

Showing top 5 for Behavior.

Effectiveness
Lack of efficacy - NOS (1) • Cat Lack of efficacy (endoparasite) - hookworm (1) • Dog Lack of efficacy (endoparasite) - heartworm (1) • Dog Lack of efficacy (ectoparasite) - flea (1) • Cat Lack of efficacy (ectoparasite) - NOS • Cat

Showing top 5 for Effectiveness.

Other
Skin scab (1) • Cat Increased percentage reticulocytes (1) • Dog Hypersensitivity reaction (1) • Cat Hair change (1) • Dog Basophilia (1) • Dog
Show more (4)
Application site scab (1) • Cat Abnormal cytology (1) • Cat Other abnormal test result NOS • Dog Death • Dog

Showing top 5 for Other.

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Adverse Event Case Summaries (openFDA)

These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.

Dog, ['Beagle', 'Dog (unknown)'], Male, 5.5 year, 13.608 kilogram • Drug: MSK, Solution, Topical • Reactions: Lack of efficacy (endoparasite) - heartworm • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-026194
  • Serious AE: Yes
  • Treated For AE: No
  • Sex: Male
  • Age: 5.50 Year
  • Weight: 13.608 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Topical
  • Form: Solution
Reactions Reported:
Lack of efficacy (endoparasite) - heartworm
Outcomes: Ongoing

Dog, ['Siberian Husky', 'Terrier - Bull - American Pit'], Female, 1 year, 19.142 kilogram • Drug: MSK, Solution, Topical • Reactions: Lack of efficacy (endoparasite) - heartworm • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-013392
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 1.00 Year
  • Weight: 19.142 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Topical
  • Form: Solution
Reactions Reported:
Lack of efficacy (endoparasite) - heartworm
Outcomes: Ongoing

Dog, Dog (unknown), Male • Drug: MSK, Solution, Topical • Reactions: Vomiting, Lack of efficacy (endoparasite) - hookworm, Diarrhea • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-011517
  • Serious AE: No
  • Treated For AE: No
  • Sex: Male
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Topical
  • Form: Solution
Reactions Reported:
Vomiting Lack of efficacy (endoparasite) - hookworm Diarrhea
Outcomes: Outcome Unknown

Dog, Collie (unspecified), Male, 9 year, 28.123 kilogram • Drug: MSK, Solution, Unknown • Reactions: Lack of efficacy (endoparasite) - heartworm • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-008926
  • Serious AE: No
  • Treated For AE: No
  • Sex: Male
  • Age: 9.00 Year
  • Weight: 28.123 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Solution
Reactions Reported:
Lack of efficacy (endoparasite) - heartworm
Outcomes: Outcome Unknown

Cat, Domestic Shorthair, Female, 15 year, 4.536 kilogram • Drug: MSK, Unassigned, Topical • Reactions: Lack of efficacy - NOS, Abnormal cytology, Hypersensitivity reaction • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-008147
  • Serious AE: No
  • Treated For AE: No
  • Sex: Female
  • Age: 15.00 Year
  • Weight: 4.536 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Topical
  • Form: Unassigned
Reactions Reported:
Lack of efficacy - NOS Abnormal cytology Hypersensitivity reaction
Outcomes: Ongoing

Dog, ['Terrier - Bull - Staffordshire', 'Terrier - Bull - American Pit'], Male, 2 year, 23.13 kilogram • Drug: MSK, Solution, Topical • Reactions: Increased percentage reticulocytes, Basophilia, Hair change • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-020962
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 2.00 Year
  • Weight: 23.130 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Topical
  • Form: Solution
Reactions Reported:
Increased percentage reticulocytes Basophilia Hair change
Outcomes: Outcome Unknown

Cat, Domestic Longhair, Female, 5 year • Drug: MSK, Solution, Topical • Reactions: Lack of efficacy (ectoparasite) - flea • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-002719
  • Serious AE: No
  • Treated For AE: No
  • Sex: Female
  • Age: 5.00 Year
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Topical
  • Form: Solution
Reactions Reported:
Lack of efficacy (ectoparasite) - flea
Outcomes: Outcome Unknown

Cat, Cat (unknown), Male, 1.5 year, 3.62 kilogram • Drug: MSK, Solution, Topical, Dose: 1 tube per animal • Reactions: Hair loss at application site, Skin scab • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-002598
  • Serious AE: No
  • Treated For AE: No
  • Sex: Male
  • Age: 1.50 Year
  • Weight: 3.620 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Topical
  • Form: Solution
  • Dose: 1 tube per animal
Reactions Reported:
Hair loss at application site Skin scab
Outcomes: Ongoing

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Overdose Information

No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.

Storage & Handling

No approved storage guidance is linked yet for this ingredient. Use manufacturer packaging and veterinary guidance for handling/storage.

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