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Robenacoxib

Detailed information about Robenacoxib

Official label facts Owner quick guide first Marketing clearly labeled
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Reviewed / Updated / Sources

Reviewed: Not available

Updated: February 12, 2026, 7:40 PM UTC

Sources:

Pet Owner Quick Guide

Start here first for the simple next-step summary.

Used for:

ONSIOR tablets are indicated for the control of postoperative pain and inflammation associated with orthopedic surgery, ovariohysterectomy and castration, in cats greaterThanEqualTo 5.5 lbs (2.5 kg) and greaterThanEqualT...

What to watch for:

  • Do not use in animals with known hypersensitivity to NSAIDs, gastrointestinal ulcers, or severe renal/hepatic dysfunction
  • Not recommended for pregnant or lactating animals
  • Vomiting (1 reports)
  • Scratching (1 reports)
  • Pyelonephritis (1 reports)

When to call the vet:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
  • Facial swelling or hives.
  • Blood in vomit or stool.

What to ask your vet today:

  • Is this medicine the right fit for my pet’s current symptoms?
  • Which warning signs mean I should call back right away?
  • How should I handle missed doses or refusal to take the medicine?
Safety & side effects

What to watch:

  • Do not use in animals with known hypersensitivity to NSAIDs, gastrointestinal ulcers, or severe renal/hepatic dysfunction
  • Not recommended for pregnant or lactating animals
  • Vomiting
  • Scratching
  • Pyelonephritis

Most reported reactions:

  • Vomiting (1 reports)
  • Scratching (1 reports)
  • Pyelonephritis (1 reports)

When to call your vet:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
Talk to a Vet / Find a Vet Near You Start Symptom Intake

Data freshness: source data appears current.

Latest refresh: Mar 21, 2026, 10:02 a.m.

Data freshness
  • Medication catalog: Source Roxee | Refreshed Feb 12, 2026, 7:40 PM UTC
  • Animal Drugs @ FDA: Source FDA | Refreshed Mar 21, 2026, 10:00 AM UTC
    Applications/products are imported from FDA export data.
  • Animal Drugs @ FDA previews: Source FDA | Refreshed Mar 10, 2026, 10:01 AM UTC
    Label highlights/doc links are fetched from FDA preview endpoints.
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed Mar 21, 2026, 10:01 AM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
  • openFDA reaction terms: Source FDA openFDA | Refreshed Mar 21, 2026, 10:02 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Feb 9, 2026, 3:19 AM UTC
Image for Robenacoxib

Robenacoxib

Drug type: Generic ingredient • Branded profile • FDA branded products available

Species: Both

Manufacturer: Not available (source)

Quick Facts

Official label facts first, then secondary summaries. Marketing content is separated below.

Species: Both
Manufacturer: Not available
Form: Injectable Solution, Injection, Tablet
Identifiers:
ANADA: 200804 ANADA: 200832 NADA: 141320 NADA: 141443 NADA: 141463 NDC Package: 58198-4875-1 NDC Package: 58198-4886-1 NDC Package: 58198-5911-0 NDC Package: 73377-097-01 NDC Package: 86117-080-16 NDC Product: 58198 NDC Product: 73377 NDC Product: 86117
Source metadata:

Warnings / Contraindications

Do not use in animals with known hypersensitivity to NSAIDs, gastrointestinal ulcers, or severe renal/hepatic dysfunction. Not recommended for pregnant or lactating animals.

  • High: Do not use in animals with known hypersensitivity to NSAIDs, gastrointestinal ulcers, or severe renal/hepatic dysfunction. Not recommended for pregnant or lactating animals.
Source metadata:

Adverse Reactions

Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.

Tap or hover a reaction to see what it means in plain language.

Tracked signals
28
Reported cases
27
Serious reports
18
Species represented
2
Grouped by Body System
Digestive (4) · Vomiting, Decreased appetite, Blood in vomit Effectiveness (1) · Lack of efficacy - NOS Other (23) · Weight loss, Underdose, Scratching
Most Reported Reactions
Reaction Body system Cases Species Serious cases
Digestive 1 Cat 1
Other 1 Dog 1
Other 1 Cat 1
Other 1 Cat 1
Effectiveness 1 Dog 1
Other 1 Dog 1
Other 1 Dog 1
Other 1 Dog 1

Species coverage: Cat (18) Dog (10)

View detailed reaction table
Reaction Body system Species Seriousness Frequency Reports
Other Cat Non-serious - 1
Digestive Cat Serious - 1
Other Cat Non-serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Other Dog Non-serious - 1
Other Dog Non-serious - 1
Other Cat Serious - 1
Effectiveness Dog Serious - 1
Other Dog Non-serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Cat Non-serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Other Cat Non-serious - 1
Other Cat Non-serious - 1
Other Dog Non-serious - 1
Other Cat Serious - 1
Digestive Cat Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Dog Serious - 1
Digestive Cat Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Digestive Cat Unknown - -
Source metadata:

Storage & Handling

Store at controlled room temperature (15–25°C); keep tablets in their blister pack, protected from moisture and light.

Documents

Owner handouts and official technical documents are grouped for faster access.

Owner handouts (0)
  • No owner handouts linked yet.
Official label / PI (8)
  • UCM304417.pdf · Labeling
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/document/downloadLabeling/14
  • N-141320-C-0047-NL-AA_PI.pdf · Labeling
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/document/downloadLabeling/743
  • N-141443-C-0014-NL-AA_PI.pdf · Labeling
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/document/downloadLabeling/745
  • A-200804-E-0004-OT-AA_PI.pdf · Labeling
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/document/downloadLabeling/2419
  • A-200832-A-0000-OT-AA_PI.pdf · Labeling
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/document/downloadLabeling/2341
  • A-200832-A-0000-OT-AA_CIS.pdf · Labeling
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/document/downloadLabeling/2342
  • Onsior_PI.pdf · Labeling
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/document/downloadLabeling/201
  • Onsior_CI.pdf · Labeling
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/document/downloadLabeling/202
SPL (5)
  • onsior® Tablets for Cats · SPL
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/spl/file/2218/onsior%C2%AE%20Tablets%20for%20Cats
  • onsior® injection · SPL
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/spl/file/2349/onsior%C2%AE%20injection
  • Robenacoxib Injection · SPL
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/spl/file/18492/Robenacoxib%20Injection
  • Robenacoxib · SPL
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/spl/file/18160/Robenacoxib
  • onsior™ · SPL
    https://animaldrugsatfda.fda.gov/adafda/app/search/public/spl/file/2564/onsior%E2%84%A2
FOI (7)
Source metadata:
Veterinary reference (advanced)

Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.

At a Glance

Quick facts and links to official labeling and safety signals.

Data freshness
  • Medication catalog: Source Roxee | Refreshed Feb 12, 2026, 7:40 PM UTC
  • Animal Drugs @ FDA: Source FDA | Refreshed Mar 21, 2026, 10:00 AM UTC
    Applications/products are imported from FDA export data.
  • Animal Drugs @ FDA previews: Source FDA | Refreshed Mar 10, 2026, 10:01 AM UTC
    Label highlights/doc links are fetched from FDA preview endpoints.
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed Mar 21, 2026, 10:01 AM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
  • openFDA reaction terms: Source FDA openFDA | Refreshed Mar 21, 2026, 10:02 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Feb 9, 2026, 3:19 AM UTC
Official (FDA)
Identity: Generic ingredient • FDA branded products available
Official FDA brands: Robenacoxib Robenacoxib Injection onsior® Tablets for Cats onsior® injection onsior™
Case-reported brands (openFDA): MSK
Catalog species: Both • FDA-labeled species: Cat, Dog
Rx/OTC: RX
Form/route: Injectable Solution, Injection, Tablet • Oral, Subcutaneous
Applications: NADA 141-320 • NADA 141-443 • ANADA 200-804 • ANADA 200-832 • NADA 141-463
NDC: Packages 73377-097-01 • Products 73377
Documents: 15 (FOI: 7) • SPL: 5 • Label highlights • Official documents
Safety (openFDA)
Top reactions: Dog 8 • Cat 25 • View
Case summaries: 10 (showing 8) • View
openFDA reports are unverified and do not prove causation.
Explore
Related conditions: Pain (acute, chronic)
Linked using: Fda_Label (0.95)
Diagnosis Codes

Diagnosis-code mappings are not available for this medication yet.

Counseling and Monitoring Highlights

Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.

Owner-facing counseling points
  • Do not use in animals with known hypersensitivity to NSAIDs, gastrointestinal ulcers, or severe renal/hepatic dysfunction. Not recommended for pregnant or lactating animals. (Contraindication, High)
Top reaction signals
Vomiting (1) Scratching (1) Pyelonephritis (1) Malaise (1) Lack of efficacy - NOS (1) Increased respiratory rate (1) Increased heart rate (1) Hypertension (1)

Identifiers & Packages

Normalized identifiers (NDC/NADA/ANADA) and package metadata from regulator listings.

Identifiers
ANADA: 200804 ANADA: 200832 NADA: 141320 NADA: 141443 NADA: 141463 NDC Package: 58198-4875-1 NDC Package: 58198-4886-1 NDC Package: 58198-5911-0 NDC Package: 73377-097-01 NDC Package: 86117-080-16 NDC Product: 58198 NDC Product: 73377 NDC Product: 86117
Package NDC Product NDC Form / Route Status
58198-4875-1 58198 -
58198-4886-1 58198 -
58198-5911-0 58198 -
73377-097-01 73377 -
86117-080-16 86117 -

Enriched Documents

Documents are tiered by source trust: Official, Clinical, Manufacturer, Marketing.

Data Sources & Change Log

Every non-trivial field is expected to include provenance and update timestamps.

Official 18 Clinical 2 Manufacturer 0 Marketing 0
Current Field Facts
  • overdose_info: Overdose may result in severe GI ulceration, vomiting (possibly with blood), or renal failure. Urgent supportive care is required. (Clinical, 2026-02-12)
  • storage_handling: Store at controlled room temperature (15–25°C); keep tablets in their blister pack, protected from moisture and light. (Clinical, 2026-02-12)
  • contraindications: Do not use in animals with known hypersensitivity to NSAIDs, gastrointestinal ulcers, or severe renal/hepatic dysfunction. Not recommended for pregnant or lact… (Official, 2026-02-12)
  • side_effects: May cause GI upset (vomiting, diarrhea), reduced appetite; rare cases of severe kidney or GI complications have been reported. (Official, 2026-02-12)
  • usage: COX-2 selective NSAID used for short-term control of postoperative pain and inflammation in cats and dogs. (Official, 2026-02-12)
Recent Revisions
  • side_effects updated 2026-02-12 19:40 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-02-12 19:40 by etl_backfill • Backfilled from existing medication fields
  • usage updated 2026-02-12 19:40 by etl_backfill • Backfilled from existing medication fields

FDA Products & Applications (Animal Drugs @ FDA)

Official sponsor/proprietary-name/application-status records linked by active ingredient.

Product Sponsor Application Status Published
onsior® Tablets for Cats
RX
Robenacoxib
Tablet • Oral
Label highlights
Official documents
Elanco US Inc. NADA 141-320 Approved Mar 16, 2026
onsior® injection
RX
Robenacoxib
Injection • Subcutaneous
Label highlights
Official documents
Elanco US Inc. NADA 141-443 Approved Mar 9, 2026
Robenacoxib Injection
RX
Robenacoxib
Injectable Solution • Subcutaneous
Label highlights
Official documents
Cronus Pharma Specialities India Private Ltd. ANADA 200-804 Approved Mar 9, 2026
Robenacoxib
RX
Robenacoxib
Tablet • Oral
Label highlights
Official documents
ZYVET AH, Inc. ANADA 200-832 Approved Jan 21, 2026
onsior™
RX
Robenacoxib
Tablet • Oral
Label highlights
Official documents
Elanco US Inc. NADA 141-463 Approved Mar 8, 2018

Data source: FDA Animal Drugs @ FDA (public search export).

What It's For (FDA Label Highlights)

Extracted from FDA Animal Drugs @ FDA product labeling. Always confirm details with your veterinarian.

Species: Cat, No Use Class Stated Or Implied
Composition / specifications
Each tablet contains 6 mg robenacoxib.
Cats
Indication

ONSIOR tablets are indicated for the control of postoperative pain and inflammation associated with orthopedic surgery, ovariohysterectomy and castration, in cats greaterThanEqualTo 5.5 lbs (2.5 kg) and greaterThanEqualTo 4 months of age; for up to a maximum of 3 days.

Dosage

The dose of ONSIOR tablets is 0.45 mg/lb (1 mg/kg) orally once daily, for a maximum of 3 days.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Dog, No Use Class Stated Or Implied • Cat, No Use Class Stated Or Implied
Composition / specifications
20 mg/mL
Cats
Indication

ONSIOR (robenacoxib) injection is indicated for the control of postoperative pain and inflammation associated with orthopedic surgery, ovariohysterectomy and castration in cats greaterThanEqualTo 4 months of age; for up to a maximum of 3 days.

Dosage

For subcutaneous injection in cats greaterThanEqualTo 4 months of age; for up to a maximum of 3 days. To ensure accuracy of dosing, the use of a 1 mL graduated syringe is recommended. The first dose should be administered approximately 30 minutes prior to surgery, at the same time as the pre-anesthetic agents are given.

Subsequent doses can be given via subcutaneous injection, or interchanged with the oral tablet in cats greaterThanEqualTo 5.5 lbs and greaterThanEqualTo 4 months of age, for a maximum of 3 total ONSIOR doses over 3 days, not to exceed one dose per day (see Animal Safety and ONSIOR tablet product insert).

Limitations
Dogs
Indication

ONSIOR (robenacoxib) injection is indicated for the control of postoperative pain and inflammation associated with soft tissue surgery in dogs greaterThanEqualTo 4 months of age; for up to a maximum of 3 days.

Dosage

For subcutaneous injection in dogs greaterThanEqualTo 4 months of age; for up to a maximum of 3 days. The first dose should be administered approximately 45 minutes prior to surgery, at the same time as the pre-anesthetic agents are given.

Subsequent doses can be given via subcutaneous injection, or interchanged with the oral tablet in dogs greaterThanEqualTo 5.5 lbs and greaterThanEqualTo 4 months of age, for a maximum of 3 total ONSIOR doses over 3 days, not to exceed one dose per day (see Animal Safety and ONSIOR tablet product insert). If subsequent doses are given by subcutaneous injection, different sites for each injection should be used (See Adverse Reactions).

Limitations

FDA page: Open in Animal Drugs @ FDA

Composition / specifications
Each milliliter of solution contains 20 milligrams (mg) robenacoxib
Dogs
Indication

Robenacoxib Injection is indicated for the control of postoperative pain and inflammation associated with soft tissue surgery in dogs greaterThanEqualTo 4 months of age; for up to a maximum of 3 days.

Dosage

Administer 0.91 mg per pound (2 mg/kilogram (kg)) by subcutaneous injection, once daily, for a maximum of 3 days. After the initial subcutaneous dose, subsequent doses can be given by subcutaneous injection or as the oral tablet in dogs weighing at least 5.5 pounds (2.5 kg) and at least 4 months of age, for a maximum of 3 total doses over 3 days, not to exceed 1 dose per day.

Limitations
Cats
Indication

Robenacoxib Injection is indicated for the control of postoperative pain and inflammation associated with orthopedic surgery, ovariohysterectomy and castration in cats greaterThanEqualTo 4 months of age; for up to a maximum of 3 days.

Dosage

Administer 0.91 mg per pound (2 mg/kg) by subcutaneous injection, once daily, for a maximum of 3 days.

Limitations

FDA page: Open in Animal Drugs @ FDA

Composition / specifications
6 mg robenacoxib per tablet
Cats
Indication

For the control of postoperative pain and inflammation associated with orthopedic surgery, ovariohysterectomy and castration, in cats greaterThanEqualTo 5.5 lbs (2.5 kg) and greaterThanEqualTo 4 months of age; for up to a maximum of 3 days.

Dosage

Administer 0.45 mg/lb (1 mg/kg) orally, once daily, for a maximum of 3 days.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Dog, No Use Class Stated Or Implied
Composition / specifications
Tablets contain 10, 20, or 40 mg of robenacoxib.
Dogs
Indication
For the control of postoperative pain and inflammation associated with soft tissue surgery in dogs greater at least 5.5 lbs (2.5 kg) and at least 4 months of age; for up to a maximum of 3 days.
Dosage
0.91 mg/lb (2mg/kg) orally once daily, for a maximum of three days.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian.

FDA page: Open in Animal Drugs @ FDA

Official Documents (FDA)

Direct links to FDA-hosted PDFs and SPL packages (when available).

Documents
  • Summary
    This supplement provides for lowering the age limit to > 4 months of age. All cats should still meet the minimum weight requirement of 5.5 lbs (2.5 kg).
  • Summary
    ONSIOR tablets are indicated for the control of postoperative pain and inflammation associated with orthopedic surgery, ovariohysterectomy and castration in cats > 5.5 lbs (2.5 kg) and > 6 months of age; for up to a maximum of 3 days.
  • Labeling UCM304417.pdf
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    For the control of postoperative pain and inflammation associated with soft tissue surgery in dogs > 4 months of age; for up to a maximum of 3 days.
  • Summary
    For the control of postoperative pain and inflammation associated with orthopedic surgery, ovariohysterectomy and castration in cats = 4 months of age; for up to a maximum of 3 days.
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary

    Dogs: Robenacoxib Injection is indicated for the control of postoperative pain and inflammation associated with soft tissue surgery in dogs greaterThanEqualTo 4 months of age; for up to a maximum of 3 days.
    Cats: Robenacoxib Injection is indicated for the control of postoperative pain and inflammation associated with orthopedic surgery, ovariohysterectomy and castration in cats greaterThanEqualTo 4 months of age; for up to a maximum of 3 days.

SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Documents
  • Summary
    For the control of postoperative pain and inflammation associated with soft tissue surgery in dogs = 5.5 lbs (2.5 kg) and = 4 months of age; for up to a maximum of 3 days.
  • Labeling Onsior_PI.pdf
  • Labeling Onsior_CI.pdf
SPL Packages

FDA page: Open in Animal Drugs @ FDA

Usage

COX-2 selective NSAID used for short-term control of postoperative pain and inflammation in cats and dogs.

Source: FDA Animal Drugs @ FDA • Reference

Contraindications

Do not use in animals with known hypersensitivity to NSAIDs, gastrointestinal ulcers, or severe renal/hepatic dysfunction. Not recommended for pregnant or lactating animals.

Side Effects

May cause GI upset (vomiting, diarrhea), reduced appetite; rare cases of severe kidney or GI complications have been reported.

Source: FDA openFDA • Reference

Top Reported Reactions (openFDA)

De-duplicated reaction terms grouped by body system from FDA openFDA reports (not verified; does not prove causation).

Digestive
Vomiting (1) • Cat Decreased appetite (1) • Cat Blood in vomit (1) • Cat Loss of appetite • Cat

Showing top 5 for Digestive.

Effectiveness
Lack of efficacy - NOS (1) • Dog

Showing top 5 for Effectiveness.

Other
Weight loss (1) • Cat Underdose (1) • Cat Scratching (1) • Dog Pyelonephritis (1) • Cat Pain NOS (1) • Dog
Show more (18)
Other abnormal test result NOS (1) • Dog Malaise (1) • Cat IRON LOW, BLOOD (1) • Dog Increased respiratory rate (1) • Dog Increased heart rate (1) • Dog Hyperthermia (1) • Cat Hypertension (1) • Dog Hyperglycaemia (1) • Cat Gum disorder NOS (1) • Cat Elevated temperature (1) • Cat Elevated C-reactive protein (1) • Dog Elevated betahydroxybutyrate (1) • Cat Death (1) • Cat Constipation (1) • Cat Cardiac arrest (1) • Dog Blood in urine (1) • Cat Blood clot (1) • Cat Anaphylaxis (1) • Cat

Showing top 5 for Other.

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Adverse Event Case Summaries (openFDA)

These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.

Cat, Domestic Longhair, Male, 6 month, 2.631 kilogram • Drug: MSK, Unassigned, Oral • Reactions: Hyperthermia, Underdose • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-056102
  • Serious AE: No
  • Treated For AE: No
  • Sex: Male
  • Age: 6.00 Month
  • Weight: 2.631 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Unassigned
Reactions Reported:
Hyperthermia Underdose
Outcomes: Ongoing

Cat, Domestic Shorthair, Male, 16 year, 4.53 kilogram • Drug: MSK, Injection, Unknown • Reactions: Pain NOS, Pyelonephritis, Blood clot, Constipation, Malaise… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-055974
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 16.00 Year
  • Weight: 4.530 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Injection
Reactions Reported:
Pain NOS Pyelonephritis Blood clot Constipation Malaise Blood in urine Decreased appetite Hyperglycaemia Elevated betahydroxybutyrate
Outcomes: Ongoing

Cat, Snowshoe, Male, 1 year, 4.264 kilogram • Drug: MSK, Injection, Unknown, Dose: 1 tablet per animal • Reactions: Vomiting, Blood in vomit, Death, Anaphylaxis • Outcome: Died

  • Report ID: USA-USFDACVM-2025-US-055626
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 1.00 Year
  • Weight: 4.264 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Injection
  • Dose: 1 tablet per animal
Reactions Reported:
Vomiting Blood in vomit Death Anaphylaxis
Outcomes: Died

Cat, Domestic Shorthair, Male, 10 year, 4.926 kilogram • Drug: MSK, Tablet, Oral, Dose: 1 tablet per animal, Frequency: 24 per hour • Reactions: Vomiting • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-055800
  • Serious AE: No
  • Treated For AE: No
  • Sex: Male
  • Age: 10.00 Year
  • Weight: 4.926 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet
  • Dose: 1 tablet per animal
  • Frequency: 24 per hour
Reactions Reported:
Vomiting
Outcomes: Ongoing

Cat, Domestic Shorthair, Male, 6 year, 6.35 kilogram • Drug: MSK, Injection, Subcutaneous, Dose: 0.50 mL per animal, Frequency: 1 per day • Reactions: Elevated temperature, Decreased appetite, Weight loss, Gum disorder NOS • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-055975
  • Serious AE: No
  • Treated For AE: No
  • Sex: Male
  • Age: 6.00 Year
  • Weight: 6.350 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Subcutaneous
  • Form: Injection
  • Dose: 0.50 mL per animal
  • Frequency: 1 per day
Reactions Reported:
Elevated temperature Decreased appetite Weight loss Gum disorder NOS
Outcomes: Ongoing

Dog, Dog (unknown), Mixed, 1 year, 8 kilogram • Drug: MSK, Oral • Reactions: Elevated C-reactive protein, Pain NOS, Other abnormal test result NOS, IRON LOW, BLOOD • Outcome: Outcome Unknown

  • Report ID: ESP-USFDACVM-2025-ES-000003
  • Serious AE: No
  • Treated For AE: No
  • Sex: Mixed
  • Age: 1.00 Year
  • Weight: 8.000 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
Reactions Reported:
Elevated C-reactive protein Pain NOS Other abnormal test result NOS IRON LOW, BLOOD
Outcomes: Outcome Unknown

Dog, Spaniel - Portuguese Water, Female, 7 year, 17 kilogram • Drug: MSK, Subcutaneous • Reactions: Increased heart rate, Increased respiratory rate, Hypertension • Outcome: Recovered/Normal

  • Report ID: SWE-USFDACVM-2024-SE-000007
  • Serious AE: Yes
  • Treated For AE: No
  • Sex: Female
  • Age: 7.00 Year
  • Weight: 17.000 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Subcutaneous
Reactions Reported:
Increased heart rate Increased respiratory rate Hypertension
Outcomes: Recovered/Normal

Dog, Chihuahua, Female, 9 year, 6.35 kilogram • Drug: MSK, Unknown • Reactions: Increased heart rate, Scratching, Cardiac arrest • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2024-US-077252
  • Serious AE: Yes
  • Treated For AE: No
  • Sex: Female
  • Age: 9.00 Year
  • Weight: 6.350 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Increased heart rate Scratching Cardiac arrest
Outcomes: Recovered/Normal

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Overdose Information

Overdose may result in severe GI ulceration, vomiting (possibly with blood), or renal failure. Urgent supportive care is required.

Storage & Handling

Store at controlled room temperature (15–25°C); keep tablets in their blister pack, protected from moisture and light.

Share Your Thoughts

Let others know your experience or advice regarding this medication.

This medication has not been reviewed by a veterinarian yet.