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Meds A-Z

Milbemcyin Oxime, Lufenuron, Praziquantel

Detailed information about Milbemcyin Oxime, Lufenuron, Praziquantel

Official label facts Owner quick guide first Marketing clearly labeled
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Reviewed / Updated / Sources

Reviewed: Not available

Updated: February 12, 2026, 10:44 PM UTC

Sources:

Pet Owner Quick Guide

Start here first for the simple next-step summary.

Used for:

Your vet decides this. Here's what owners typically ask/watch for.

What to watch for:

  • wobbly/unsteady walking (1 reports)
  • Seizure NOS (1 reports)
  • Inappetence (1 reports)

When to call the vet:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
  • Facial swelling or hives.
  • Blood in vomit or stool.

What to ask your vet today:

  • Is this medicine the right fit for my pet’s current symptoms?
  • Which warning signs mean I should call back right away?
  • How should I handle missed doses or refusal to take the medicine?
Safety & side effects

What to watch:

  • wobbly/unsteady walking
  • Seizure NOS
  • Inappetence

Most reported reactions:

  • Unsteady walking (ataxia) (1 reports)
  • Seizure NOS (1 reports)
  • Inappetence (1 reports)

When to call your vet:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
Talk to a Vet / Find a Vet Near You Start Symptom Intake

Data freshness: source data appears current.

Latest refresh: Mar 21, 2026, 10:01 a.m.

Data freshness
  • Medication catalog: Source Roxee | Refreshed Feb 12, 2026, 10:44 PM UTC
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed Mar 21, 2026, 10:01 AM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
  • openFDA reaction terms: Source FDA openFDA | Refreshed Feb 9, 2026, 3:13 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Feb 9, 2026, 3:20 AM UTC
Image coming soon
Milbemcyin Oxime, Lufenuron, Praziquantel

Milbemcyin Oxime, Lufenuron, Praziquantel

Drug type: Generic ingredient • Generic profile • No FDA branded products linked

Species: Both

Manufacturer: Not available (source)

Quick Facts

Official label facts first, then secondary summaries. Marketing content is separated below.

Species: Both
Manufacturer: Not available

Adverse Reactions

Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.

Tap or hover a reaction to see what it means in plain language.

Tracked signals
15
Reported cases
9
Serious reports
5
Species represented
2
Grouped by Body System
Digestive (2) · Vomiting, Diarrhea Neurologic (4) · Unsteady walking (ataxia), Tiredness (lethargy), Seizure NOS Effectiveness (3) · Lack of efficacy, Lack of efficacy (endoparasite) - tapeworm, Lack of efficacy (endoparasite) - hookworm Other (6) · Inappetence, Disorientation, Accidental exposure
Most Reported Reactions
Reaction Body system Cases Species Serious cases
Neurologic 1 Cat 1
Neurologic 1 Cat 1
Other 1 Cat 1
Other 1 Cat 1
Other 1 Cat 1
Digestive 1 Dog 0
Neurologic 1 Cat 0
Effectiveness 1 Dog 0

Species coverage: Dog (9) Cat (6)

View detailed reaction table
Reaction Body system Species Seriousness Frequency Reports
Digestive Dog Non-serious - 1
Neurologic Cat Serious - 1
Neurologic Cat Non-serious - 1
Neurologic Cat Serious - 1
Effectiveness Dog Non-serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Digestive Dog Non-serious - 1
Other Cat Serious - 1
Neurologic Dog Unknown - -
Effectiveness Dog Unknown - -
Effectiveness Dog Unknown - -
Other Dog Unknown - -
Other Dog Unknown - -
Other Dog Unknown - -
Source metadata:
Veterinary reference (advanced)

Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.

At a Glance

Quick facts and links to official labeling and safety signals.

Data freshness
  • Medication catalog: Source Roxee | Refreshed Feb 12, 2026, 10:44 PM UTC
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed Mar 21, 2026, 10:01 AM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
  • openFDA reaction terms: Source FDA openFDA | Refreshed Feb 9, 2026, 3:13 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Feb 9, 2026, 3:20 AM UTC
Official (FDA)
Identity: Generic ingredient • No FDA branded products linked
No official FDA brand rows linked yet for this ingredient.
Case-reported brands (openFDA): MSK
Catalog species: Both
Safety (openFDA)
Top reactions: Dog 8 • Cat 6 • View
Case summaries: 7 (showing 7) • View
openFDA reports are unverified and do not prove causation.
Diagnosis Codes

Diagnosis-code mappings are not available for this medication yet.

Counseling and Monitoring Highlights

Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.

Top reaction signals
Unsteady walking (ataxia) (1) Seizure NOS (1) Inappetence (1) Disorientation (1) Accidental exposure (1) Vomiting (1) Tiredness (lethargy) (1) Lack of efficacy (1)

Data Sources & Change Log

Every non-trivial field is expected to include provenance and update timestamps.

Official 1 Clinical 0 Manufacturer 0 Marketing 0
Current Field Facts
  • side_effects: Top reported reactions (openFDA): INEFFECTIVE, HEARTWORM LARVAE, Vomiting, Lack of efficacy (endoparasite) - hookworm, INEFFECTIVE, ASCARIDS NOS, Diarrhoea, IN… (Official, 2026-02-12)
Recent Revisions
  • side_effects updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields

Top Reported Reactions (openFDA)

De-duplicated reaction terms grouped by body system from FDA openFDA reports (not verified; does not prove causation).

Digestive
Vomiting (1) • Dog Diarrhea (1) • Dog

Showing top 5 for Digestive.

Neurologic
Unsteady walking (1) • Cat Tiredness (1) • Cat Seizure NOS (1) • Cat Tiredness (lethargy) • Dog

Showing top 5 for Neurologic.

Effectiveness
Lack of efficacy (1) • Dog Lack of efficacy (endoparasite) - tapeworm • Dog Lack of efficacy (endoparasite) - hookworm • Dog

Showing top 5 for Effectiveness.

Other
Inappetence (1) • Cat Disorientation (1) • Cat Accidental exposure (1) • Cat INEFFECTIVE, HOOKS • Dog INEFFECTIVE, HEARTWORM LARVAE • Dog
Show more (1)
INEFFECTIVE, ASCARIDS NOS • Dog

Showing top 5 for Other.

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Adverse Event Case Summaries (openFDA)

These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.

Dog, Mastiff, Female, 15 month, 41.73 kilogram • Drug: MSK, Tablet, chewable, Oral, Dose: 1 tablet per dose, Frequency: 1 per day • Reactions: Lack of efficacy • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2018-US-014918
  • Serious AE: No
  • Treated For AE: No
  • Sex: Female
  • Age: 15.00 Month
  • Weight: 41.730 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet, chewable
  • Dose: 1 tablet per dose
  • Frequency: 1 per day
Reactions Reported:
Lack of efficacy
Outcomes: Outcome Unknown

Dog, Retriever - Labrador, Female, 6.5 year, 37.934 kilogram • Drug: MSK, Tablet, chewable, Oral, Dose: 1 tablet per dose, Frequency: 1 per day • Reactions: Vomiting, Diarrhea • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2018-US-008732
  • Serious AE: No
  • Treated For AE: Yes
  • Sex: Female
  • Age: 6.50 Year
  • Weight: 37.934 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet, chewable
  • Dose: 1 tablet per dose
  • Frequency: 1 per day
Reactions Reported:
Vomiting Diarrhea
Outcomes: Recovered/Normal

Dog, Poodle - Miniature, Male, 10 year, 5.897 kilogram • Drug: MSK, Tablet, chewable, Oral, Dose: 1 tablet per dose, Frequency: 1 per day • Reactions: Vomiting • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2018-US-008809
  • Serious AE: No
  • Treated For AE: No
  • Sex: Male
  • Age: 10.00 Year
  • Weight: 5.897 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet, chewable
  • Dose: 1 tablet per dose
  • Frequency: 1 per day
Reactions Reported:
Vomiting
Outcomes: Recovered/Normal

Dog, Dog (unknown), Female, 14.5 year, 5.897 kilogram • Drug: MSK, Tablet, chewable, Oral, Dose: 1 tablet per dose, Frequency: 30 per day • Reactions: Lack of efficacy • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2018-US-008493
  • Serious AE: No
  • Treated For AE: No
  • Sex: Female
  • Age: 14.50 Year
  • Weight: 5.897 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet, chewable
  • Dose: 1 tablet per dose
  • Frequency: 30 per day
Reactions Reported:
Lack of efficacy
Outcomes: Outcome Unknown

Dog, Dachshund - Standard Long-haired, Male, 5 year, 7.257 kilogram • Drug: MSK, Tablet, chewable, Oral, Dose: 1 tablet per dose, Frequency: 1 per day • Reactions: Vomiting • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2018-US-007962
  • Serious AE: No
  • Treated For AE: No
  • Sex: Male
  • Age: 5.00 Year
  • Weight: 7.257 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet, chewable
  • Dose: 1 tablet per dose
  • Frequency: 1 per day
Reactions Reported:
Vomiting
Outcomes: Recovered/Normal

Cat, Domestic Shorthair, Male, 21 month, 3.266 kilogram • Drug: MSK, Tablet, chewable, Oral, Dose: 1 tablet per dose, Frequency: 1 per day • Reactions: Disorientation, Unsteady walking (ataxia), Inappetence, Seizure NOS, Accidental exposure • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2018-US-001004
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 21.00 Month
  • Weight: 3.266 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet, chewable
  • Dose: 1 tablet per dose
  • Frequency: 1 per day
Reactions Reported:
Disorientation Unsteady walking (ataxia) Inappetence Seizure NOS Accidental exposure
Outcomes: Recovered/Normal

Cat, Domestic Shorthair, Male, 6 year, 7.257 kilogram • Drug: MSK, Tablet, chewable, Oral, Dose: 1 tablet per dose, Frequency: 1 per day • Reactions: Tiredness (lethargy), Accidental exposure • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2017-US-054203
  • Serious AE: No
  • Treated For AE: Yes
  • Sex: Male
  • Age: 6.00 Year
  • Weight: 7.257 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet, chewable
  • Dose: 1 tablet per dose
  • Frequency: 1 per day
Reactions Reported:
Tiredness (lethargy) Accidental exposure
Outcomes: Recovered/Normal

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Overdose Information

No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.

Storage & Handling

No approved storage guidance is linked yet for this ingredient. Use manufacturer packaging and veterinary guidance for handling/storage.

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