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Roxee Medication Guide
Medication reference facts with explicit FDA-approval, off-label, source-limited, and safety context. Roxee does not sell, prescribe, or dispense medications.
Veterinary professional?
Roxee is still reviewing source support for this medication profile.
Roxee has safety or ingredient evidence for this medication, but a regulatory product/application match is still pending.
openFDA reaction terms and case summaries are supporting evidence, not proof of causality.
Drug type: Biologic/vaccine record • Generic profile • Biologic/vaccine record
Species: Both
Approval status: Vaccine or biologic source record. This record is tracked as vaccine, biologic, strain, recombinant, or lot-level source data. It is not labeled here as an FDA-approved animal drug; use the source documents and veterinarian guidance.
Merged from the current Roxee medication system with field-level provenance, freshness, and completeness tracking.
Top reported reactions (openFDA): Vomiting, Diarrhoea, Lethargy (see also Central nervous system depression in 'Neurological'), Lethargy (see also Central nervous system depression in Neurological), Other abnormal test result NOS, Not eating.
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Used for:
Your vet decides this. Here's what owners typically ask/watch for.
Dosing note:
Exact dosing depends on your pet's species, weight, and health status. Use your veterinarian's instructions for the exact dose and schedule.
What to watch for:
When to call the vet:
Bloodwork changes are grouped in Vet View.
What to tell or ask your vet today:
A source-aware map of what to know, what is uncertain, and what to verify with your veterinarian.
Roxee has limited cited overview evidence for Bordetella Vaccine; use the official documents and your veterinarian's instructions for product-specific decisions.
32 tracked reaction signals; 32 reported cases; 26 serious reports; 2 species groups. These are reporting and label-derived signals for interpretation with a veterinarian.
Adverse-event reports help form a watch list, but they do not prove the medication caused the reaction and they are not a risk ranking between medications.
Official labels, package inserts, and reviewed summaries carry more weight than isolated reports.
Case reports and openFDA terms are useful for pattern awareness, but they are incomplete, can include multiple exposures, and do not estimate an individual pet's probability of harm.
Loss of appetite (1 reports), Elevated globulins (1 reports), Elevated creatinine (1 reports), Elevated blood urea nitrogen (1 reports), Elevated aspartate aminotransferase (1 reports)
Digestive (4), Neurologic (1), Other (27)
Dog (28 reports), Cat (4 reports)
Crossbred Canine/dog (2), Shepherd Dog - Belgian Malinois (1), ['Siberian Husky', 'Terrier - Bull - American Pit'] (1), ['Retriever - Labrador', 'Dog (unknown)'] (1). These are report metadata, not proof that a breed is at higher risk.
Verify whether Bordetella Vaccine fits the pet's species, current diagnosis, age, weight, organ status, pregnancy/lactation status, and concurrent medications.
Separate label-backed warnings from adverse-event reports and owner observations before changing the plan.
Loss of appetite, Elevated globulins
Repeated vomiting or diarrhea. Severe lethargy (hard to wake, very low energy). Collapse or fainting.
Review status / Updated / Sources
Review status: Clinical reviewer not listed
Updated: April 22, 2026, 10:07 AM UTC
Side effects to monitor:
Most reported reactions:
Emergency warning signs:
Source-backed clinical checkpoints for quick review.
Official label facts first, then secondary summaries. Marketing content is separated below.
Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.
Filter stored openFDA reports by pet and report attributes. Counts describe reports in this data set, not risk.
Received 2026-03-25 · MSK · MSK
Received 2026-03-25 · MSK · MSK
Received 2026-03-21 · MSK · MSK
Received 2026-03-19 · MSK · MSK
Received 2026-03-19 · MSK · MSK
Received 2026-03-18 · MSK · MSK
Received 2026-03-18 · MSK · MSK
Received 2026-03-05 · MSK · MSK
Received 2026-02-10 · MSK · MSK
Received 2026-02-05 · MSK · MSK
Received 2025-12-23 · MSK · MSK
Received 2025-12-23 · MSK · MSK
Received 2025-12-23 · MSK · MSK
Received 2025-12-23 · MSK · MSK
Received 2025-12-20 · MSK · MSK
Received 2025-12-18 · MSK · MSK
Received 2025-12-18 · MSK · MSK
Received 2025-12-16 · MSK · MSK
Received 2025-12-10 · MSK · MSK
Received 2025-12-02 · MSK · MSK
Received 2025-11-11 · MSK · MSK
Tap or hover a reaction to see what it means in plain language.
| Reaction | Body system | Cases | Species | Serious cases |
|---|---|---|---|---|
| Digestive | 1 | Dog | 1 | |
| Other | 1 | Cat | 1 | |
| Other | 1 | Dog | 1 | |
| Other | 1 | Dog | 1 | |
| Other | 1 | Dog | 1 | |
| Other | 1 | Dog | 1 | |
| Other | 1 | Dog | 1 | |
| Other | 1 | Dog | 1 |
Species coverage: Dog (28) Cat (4)
| Reaction | Body system | Species | Seriousness | Frequency | Reports |
|---|---|---|---|---|---|
| Neurologic | Dog | Non-serious | - | 1 | |
| Digestive | Dog | Serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Dog | Non-serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Dog | Non-serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Digestive | Dog | Non-serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Digestive | Dog | Serious | - | 1 | |
| Digestive | Dog | Serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Cat | Non-serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Dog | Non-serious | - | 1 | |
| Other | Dog | Serious | - | 1 |
Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.
Quick facts and links to official labeling and safety signals.
Diagnosis-code mappings are not available for this medication yet.
Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.
Every non-trivial field is expected to include provenance and update timestamps.
De-duplicated reaction terms grouped by body system from FDA openFDA reports (not verified; does not prove causation).
Showing top 5 for Digestive.
Showing top 5 for Neurologic.
Showing top 5 for Other.
Data source: FDA openFDA Animal & Veterinary adverse event reports.
These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.
Dog, Shepherd Dog - Belgian Malinois, Female, 7 year, 24.766 kilogram • Drug: MSK, Injection, Oral, Dose: 1 dose per animal • Reactions: Skin lump, Tiredness (lethargy), Immediate pain upon injection, Abnormal cytology, Medication error NOS • Outcome: Ongoing
Dog, ['Siberian Husky', 'Terrier - Bull - American Pit'], Male, 2 year, 29.483 kilogram • Drug: MSK, Unassigned, Unknown, Dose: 1 dose per animal • Reactions: Elevated aspartate aminotransferase, Vomiting, Bloody diarrhoea, Tiredness (lethargy), Hypothermia… • Outcome: Ongoing
Dog, Crossbred Canine/dog, Female, 8 year, 31.389 kilogram • Drug: MSK, Injection, powder, lyophilized, for solution, Unknown, Dose: 1 dose per animal • Reactions: Vomiting, Medication error NOS, Drug dose administration interval too long • Outcome: Recovered/Normal
Dog, Crossbred Canine/dog, Male, 8 year, 22.044 kilogram • Drug: MSK, Unknown • Reactions: Lack of efficacy (endoparasite) - hookworm • Outcome: Outcome Unknown
Dog, ['Retriever - Labrador', 'Dog (unknown)'], Male, 4 year, 28.576 kilogram • Drug: MSK, Unassigned, Nasal • Reactions: Vomiting, Diarrhea, Tiredness (lethargy), Difficulty standing, Dehydration • Outcome: Ongoing
Dog, Hound - Basset, Female, 7 year, 18.597 kilogram • Drug: MSK, Unknown • Reactions: Stumbling gait, Not eating, Seizure NOS, Neutrophilia, Proprioception deficit… • Outcome: Outcome Unknown
Dog, Retriever - Labrador, Male, 1 year, 37.82 kilogram • Drug: MSK, Unknown • Reactions: Lack of efficacy (endoparasite) - heartworm • Outcome: Outcome Unknown
Dog, Terrier - Bull - American Pit, Female, 7 year, 29.257 kilogram • Drug: MSK, Injection, Nasal • Reactions: Facial swelling (possible allergy), Hives, Administration error NOS, Hypersensitivity reaction • Outcome: Recovered/Normal
Data source: FDA openFDA Animal & Veterinary adverse event reports.
No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.
No approved storage guidance is linked yet for this ingredient. Use manufacturer packaging and veterinary guidance for handling/storage.
Let others know your experience or advice regarding this medication.
This medication has not been reviewed by a veterinarian yet.