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Roxee Meds Catalog

Cyclosporin Ointment

Medication catalog facts with explicit FDA-approval, off-label, source-limited, and safety context.

Both Source review pending Source coverage pending Owner quick guide first
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Data freshness

Storefront facts
Source review pending
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Roxee is still reviewing source support for this medication profile.

FDA applications
Regulatory match pending
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Roxee has safety or ingredient evidence for this medication, but a regulatory product/application match is still pending.

Safety reports
Safety data refreshed
May 5, 2026, 10:01 a.m.

openFDA reaction terms and case summaries are supporting evidence, not proof of causality.

Source timing details
Source timing details
  • Storefront facts: Source Roxee | Refreshed May 5, 2026, 10:05 AM UTC
    The storefront fact projection used for browse cards and quick facts.
  • openFDA reaction terms: Source FDA openFDA | Refreshed May 5, 2026, 10:04 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed May 5, 2026, 10:04 AM UTC

Evidence

Reviewed / Updated / Sources

Reviewed by: Not available

Last reviewed: April 15, 2026

Updated: April 15, 2026, 10:04 AM UTC

Sources:
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Cyclosporin Ointment

Cyclosporin Ointment

Drug type: Generic ingredient • Generic profile • Source coverage pending

Both 80% storefront ready

Species: Both

Approval status: Source coverage pending. Roxee has limited supporting content for this record, but no on-page official FDA animal-drug document is linked yet. Treat it as source-limited until the ETL backfill adds official coverage.

Medication Snapshot

Merged from the current Roxee medication system with field-level provenance, freshness, and completeness tracking.

Cyclosporin Ointment

Senvelgo (velagliflozin oral solution) is approved in cats for control of hyperglycemia associated with diabetes mellitus. Species commonly shown: Both.

Generic name
Cyclosporin Ointment
Species
Both
Completeness
80%
Validation
Incomplete

Indications / Uses

Senvelgo (velagliflozin oral solution) is approved in cats for control of hyperglycemia associated with diabetes mellitus.

Side Effects

Top reported reactions (openFDA): Squinting, Eye irritation, Lack of efficacy - NOS, Corneal ulcer, Behavioural disorder NOS, Death by euthanasia.

FAQ

Both

Source Transparency

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Pet Owner Quick Guide

Start here first for the safest next-step summary before the deeper medication detail.

Roxee still has limited plain-language guidance for this medication. Use the official documents and your veterinarian's instructions for product-specific details.

Used for:

Your vet decides this. Here's what owners typically ask/watch for.

Dosing note:

Exact dosing depends on your pet's species, weight, and health status. Use your veterinarian's instructions for the exact dose and schedule.

What to watch for:

  • wobbly/unsteady walking (1 reports)
  • Loss of appetite (1 reports)
  • Elevated gamma-glutamyl transferase (1 reports)

When to call the vet:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
  • Facial swelling or hives.
  • Blood in vomit or stool.

What to tell or ask your vet today:

  • Is this medicine the right fit for my pet’s current symptoms?
  • Which warning signs mean I should call back right away?
  • How should I handle missed doses or refusal to take the medicine?
Major cautions & emergency warning signs

Side effects to monitor:

  • wobbly/unsteady walking
  • Loss of appetite
  • Elevated gamma-glutamyl transferase

Most reported reactions:

  • Unsteady walking (ataxia) (1 reports)
  • Loss of appetite (1 reports)
  • Elevated gamma-glutamyl transferase (1 reports)

Emergency warning signs:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
Talk to a Vet / Find a Vet Near You Start Symptom Intake

Quick Facts

Official label facts first, then secondary summaries. Marketing content is separated below.

Species: Both
Manufacturer: Manufacturer not confirmed

Adverse Reactions

Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.

Tap or hover a reaction to see what it means in plain language.

Tracked signals
32
Reported cases
32
Serious reports
20
Species represented
2
Grouped by Body System
Digestive (2) · Loss of appetite, Diarrhea Skin & allergy (1) · Hair loss Neurologic (1) · Unsteady walking (ataxia) Behavior (2) · Behavioral disorder (unspecified), Aggression Other (26) · Elevated gamma-glutamyl transferase, Elevated blood urea nitrogen, Elevated alanine aminotransferase
Most Reported Reactions
Reaction Body system Cases Species Serious cases
Neurologic 1 Dog 1
Digestive 1 Cat 1
Other 1 Cat 1
Other 1 Dog 1
Other 1 Cat 1
Other 1 Dog 1
Other 1 Dog 1
Other 1 Dog 1

Species coverage: Dog (25) Cat (7)

View detailed reaction table
Reaction Body system Species Seriousness Frequency Reports
Neurologic Dog Serious - 1
Digestive Cat Serious - 1
Skin & allergy Dog Non-serious - 1
Other Cat Serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Digestive Dog Non-serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Non-serious - 1
Other Cat Non-serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Non-serious - 1
Behavior Cat Non-serious - 1
Other Dog Non-serious - 1
Other Dog Non-serious - 1
Other Dog Serious - 1
Other Dog Non-serious - 1
Behavior Cat Non-serious - 1
Other Dog Serious - 1
Other Dog Non-serious - 1
Other Dog Non-serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Source metadata:
Veterinary reference (advanced)

Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.

At a Glance

Quick facts and links to official labeling and safety signals.

Data freshness
  • Storefront facts: Source Roxee | Refreshed May 5, 2026, 10:05 AM UTC
    The storefront fact projection used for browse cards and quick facts.
  • openFDA reaction terms: Source FDA openFDA | Refreshed May 5, 2026, 10:04 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed May 5, 2026, 10:04 AM UTC
Official (FDA)
Identity: Generic ingredient • No FDA branded products linked
No official FDA brand rows linked yet for this ingredient.
Case-reported brands (openFDA): MSK
Catalog species: Both
Safety (openFDA)
Top reactions: Dog 52 • Cat 18 • View
Case summaries: 17 (showing 8) • View
openFDA reports are unverified and do not prove causation.
Diagnosis Codes

Diagnosis-code mappings are not available for this medication yet.

Counseling and Monitoring Highlights

Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.

Top reaction signals
Unsteady walking (ataxia) (1) Loss of appetite (1) Elevated gamma-glutamyl transferase (1) Elevated blood urea nitrogen (1) Elevated alanine aminotransferase (1) Decreased haematocrit (1) Death by euthanasia (1) Death (1)

Data Sources & Change Log

Every non-trivial field is expected to include provenance and update timestamps.

Official 18 Clinical 7 Manufacturer 0 Marketing 0
Current Field Facts
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-21)
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-20)
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-19)
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-17)
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-16)
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-16)
  • side_effects: Top reported reactions (openFDA): Squinting, Eye irritation, Lack of efficacy - NOS, Corneal ulcer, Behavioural disorder NOS, Death by euthanasia. (Clinical, 2026-04-11)
  • side_effects: Top reported reactions (openFDA): Squinting, Eye irritation, Lack of efficacy - NOS, Corneal ulcer, Behavioural disorder NOS, Death by euthanasia. (Official, 2026-05-05)
  • side_effects: Top reported reactions (openFDA): Squinting, Eye irritation, Lack of efficacy - NOS, Corneal ulcer, Behavioural disorder NOS, Death by euthanasia. (Official, 2026-05-03)
  • side_effects: Top reported reactions (openFDA): Squinting, Eye irritation, Lack of efficacy - NOS, Corneal ulcer, Behavioural disorder NOS, Death by euthanasia. (Official, 2026-04-30)
  • side_effects: Top reported reactions (openFDA): Squinting, Eye irritation, Lack of efficacy - NOS, Corneal ulcer, Behavioural disorder NOS, Death by euthanasia. (Official, 2026-04-29)
  • side_effects: Top reported reactions (openFDA): Squinting, Eye irritation, Lack of efficacy - NOS, Corneal ulcer, Behavioural disorder NOS, Death by euthanasia. (Official, 2026-04-28)
  • side_effects: Top reported reactions (openFDA): Squinting, Eye irritation, Lack of efficacy - NOS, Corneal ulcer, Behavioural disorder NOS, Death by euthanasia. (Official, 2026-04-27)
  • side_effects: Top reported reactions (openFDA): Squinting, Eye irritation, Lack of efficacy - NOS, Corneal ulcer, Behavioural disorder NOS, Death by euthanasia. (Official, 2026-04-26)
  • side_effects: Top reported reactions (openFDA): Squinting, Eye irritation, Lack of efficacy - NOS, Corneal ulcer, Behavioural disorder NOS, Death by euthanasia. (Official, 2026-04-25)
  • side_effects: Top reported reactions (openFDA): Squinting, Eye irritation, Lack of efficacy - NOS, Corneal ulcer, Behavioural disorder NOS, Death by euthanasia. (Official, 2026-04-17)
  • side_effects: Top reported reactions (openFDA): Squinting, Eye irritation, Lack of efficacy - NOS, Corneal ulcer, Behavioural disorder NOS, Death by euthanasia. (Official, 2026-04-16)
  • side_effects: Top reported reactions (openFDA): Squinting, Eye irritation, Lack of efficacy - NOS, Corneal ulcer, Behavioural disorder NOS, Death by euthanasia. (Official, 2026-04-15)
  • side_effects: Top reported reactions (openFDA): Squinting, Eye irritation, Lack of efficacy - NOS, Corneal ulcer, Behavioural disorder NOS, Death by euthanasia. (Official, 2026-02-12)
  • usage: Senvelgo (velagliflozin oral solution) is approved in cats for control of hyperglycemia associated with diabetes mellitus. (Official, 2026-04-21)
Recent Revisions
  • side_effects updated 2026-05-05 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-05-03 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-04-30 10:09 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-04-29 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-04-28 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-04-27 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-04-26 10:06 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-04-25 10:05 by etl_backfill • Backfilled from existing medication fields
  • monitoring updated 2026-04-21 10:07 by curated_loader • Clinical monitoring context for feline diabetes management.
  • usage updated 2026-04-21 10:07 by curated_loader • Usage statement from FDA warning letter and approved-product context.
  • drug_profile_type updated 2026-04-21 10:07 by curated_loader • FDA source confirms Senvelgo as a branded approved product.
  • manufacturer_name updated 2026-04-21 10:07 by curated_loader • FDA warning letter identifies the approved sponsor/manufacturer.
  • brand_names updated 2026-04-21 10:07 by curated_loader • FDA warning letter references Senvelgo as the approved animal drug.
  • approval_reference updated 2026-04-21 10:07 by curated_loader • Official FDA application reference for Senvelgo.
  • monitoring updated 2026-04-20 10:08 by curated_loader • Clinical monitoring context for feline diabetes management.
  • usage updated 2026-04-20 10:08 by curated_loader • Usage statement from FDA warning letter and approved-product context.
  • drug_profile_type updated 2026-04-20 10:08 by curated_loader • FDA source confirms Senvelgo as a branded approved product.
  • manufacturer_name updated 2026-04-20 10:08 by curated_loader • FDA warning letter identifies the approved sponsor/manufacturer.
  • brand_names updated 2026-04-20 10:08 by curated_loader • FDA warning letter references Senvelgo as the approved animal drug.
  • approval_reference updated 2026-04-20 10:08 by curated_loader • Official FDA application reference for Senvelgo.

Top Reported Reactions (openFDA)

De-duplicated reaction terms grouped by body system from FDA openFDA reports (not verified; does not prove causation).

Digestive
Loss of appetite (1) • Cat Diarrhea (1) • Dog

Showing top 5 for Digestive.

Skin & allergy
Hair loss (1) • Dog

Showing top 5 for Skin & allergy.

Neurologic
Unsteady walking (1) • Dog

Showing top 5 for Neurologic.

Behavior
Behavioral disorder (1) • Cat Aggression (1) • Cat

Showing top 5 for Behavior.

Other
Elevated gamma-glutamyl transferase (1) • Cat Elevated blood urea nitrogen (1) • Dog Elevated alanine aminotransferase (1) • Cat Decreased haematocrit (1) • Dog Death by euthanasia (1) • Dog
Show more (21)
Death (1) • Dog Deafness (1) • Dog Cyanotic mucous membranes (1) • Dog Cough (1) • Dog Corneal ulcer (1) • Dog Conjunctivitis (1) • Dog Conjunctival oedema (1) • Cat Congestive heart failure (1) • Dog Collapse NOS (1) • Dog Bumps on skin (1) • Dog Bronchopulmonary inflammation (1) • Dog Blepharitis (1) • Dog Atopic allergy NOS (1) • Dog Appearance, Abnormal (1) • Dog Anaemia NOS (1) • Dog Allergic skin reaction (1) • Dog Agglutination test, positive (1) • Dog Administration error NOS (1) • Dog Accidental exposure (1) • Dog Abnormal histology NOS (1) • Dog Abnormal cytology (1) • Cat

Showing top 5 for Other.

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Adverse Event Case Summaries (openFDA)

These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.

Dog, Terrier - Boston, Female, 2 year, 8.16 kilogram • Drug: MSK, Capsule, Oral, Dose: 1 tablet per animal • Reactions: Rash, Hair loss • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-075064
  • Serious AE: No
  • Treated For AE: No
  • Sex: Female
  • Age: 2.00 Year
  • Weight: 8.160 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Capsule
  • Dose: 1 tablet per animal
Reactions Reported:
Rash Hair loss
Outcomes: Ongoing

Dog, Shepherd Dog - German, Female, 10.9 year, 44.45 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Lack of efficacy - NOS, Seizure NOS, Other abnormal test result NOS, Unsteady walking (ataxia), Musculoskeletal disorder NOS… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-075291
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 10.90 Year
  • Weight: 44.450 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Unassigned
Reactions Reported:
Lack of efficacy - NOS Seizure NOS Other abnormal test result NOS Unsteady walking (ataxia) Musculoskeletal disorder NOS Elevated serum alkaline phosphatase
Outcomes: Ongoing

Cat, Domestic Shorthair, Male, 4.16 year, 6.12 kilogram • Drug: MSK, Solution, Oral, Dose: 43.20 Milligram per animal, Frequency: 1 per day • Reactions: Foaming at the mouth, UNPALATABLE, Behavioral disorder (unspecified) • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2025-US-074793
  • Serious AE: No
  • Treated For AE: No
  • Sex: Male
  • Age: 4.16 Year
  • Weight: 6.120 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Solution
  • Dose: 43.20 Milligram per animal
  • Frequency: 1 per day
Reactions Reported:
Foaming at the mouth UNPALATABLE Behavioral disorder (unspecified)
Outcomes: Recovered/Normal

Dog, ['Retriever - Labrador', 'Mastiff (unspecified)'], Male, 8 year, 57.606 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Falling, Lateral recumbency, Vomiting • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-075362
  • Serious AE: No
  • Treated For AE: No
  • Sex: Male
  • Age: 8.00 Year
  • Weight: 57.606 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Unassigned
Reactions Reported:
Falling Lateral recumbency Vomiting
Outcomes: Ongoing

Dog, Spaniel - King Charles Cavalier, Male, 6.5 year • Drug: MSK, Capsule, Unknown • Reactions: Inflammatory bowel disorder, Atopic allergy NOS, Allergic skin reaction, Blepharitis • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-074702
  • Serious AE: No
  • Treated For AE: Yes
  • Sex: Male
  • Age: 6.50 Year
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Capsule
Reactions Reported:
Inflammatory bowel disorder Atopic allergy NOS Allergic skin reaction Blepharitis
Outcomes: Outcome Unknown

Cat, Cat (unknown), Unknown, 3.6 kilogram • Drug: MSK, Solution, Unknown, Dose: 1 dose per animal • Reactions: Lack of efficacy - NOS • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-075225
  • Serious AE: No
  • Treated For AE: No
  • Sex: Unknown
  • Weight: 3.600 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Solution
  • Dose: 1 dose per animal
Reactions Reported:
Lack of efficacy - NOS
Outcomes: Outcome Unknown

Cat, Cat (unknown), Unknown • Drug: MSK, Solution, Oral, Dose: 1 tablet per animal, Frequency: 1 per day • Reactions: Behavioral disorder (unspecified) • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-074991
  • Serious AE: No
  • Treated For AE: No
  • Sex: Unknown
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Solution
  • Dose: 1 tablet per animal
  • Frequency: 1 per day
Reactions Reported:
Behavioral disorder (unspecified)
Outcomes: Outcome Unknown

Cat, Domestic Shorthair, Male, 11 year, 6.03 kilogram • Drug: MSK, Solution, Oral, Dose: 0.40 mL per animal • Reactions: Tremors, Shaking • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-074916
  • Serious AE: No
  • Treated For AE: No
  • Sex: Male
  • Age: 11.00 Year
  • Weight: 6.030 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Solution
  • Dose: 0.40 mL per animal
Reactions Reported:
Tremors Shaking
Outcomes: Outcome Unknown

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Overdose Information

No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.

Storage & Handling

No approved storage guidance is linked yet for this ingredient. Use manufacturer packaging and veterinary guidance for handling/storage.

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