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Roxee Meds Catalog

Diazepam

Medication catalog facts with explicit FDA-approval, off-label, source-limited, and safety context.

Both Catalog complete FDA data linked Rx required Liquid (Solution) Roche Vitamins, Inc. Official label facts Owner quick guide first
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Data freshness

Storefront facts
Catalog refreshed
May 5, 2026, 10:00 a.m.

These are the storefront facts Roxee uses on browse cards and quick facts.

FDA applications
FDA application data refreshed
May 5, 2026, 10:00 a.m.

Sponsor, product, and application records imported from Animal Drugs @ FDA.

Safety reports
Safety data refreshed
May 5, 2026, 10:01 a.m.

openFDA reaction terms and case summaries are supporting evidence, not proof of causality.

Source timing details
Source timing details
  • Storefront facts: Source Roxee | Refreshed May 5, 2026, 10:00 AM UTC
    The storefront fact projection used for browse cards and quick facts.
  • Animal Drugs @ FDA: Source FDA | Refreshed May 5, 2026, 10:00 AM UTC
    Applications/products are imported from FDA export data.
  • Animal Drugs @ FDA previews: Source FDA | Refreshed Feb 9, 2026, 3:05 AM UTC
    Label highlights/doc links are fetched from FDA preview endpoints.
  • openFDA reaction terms: Source FDA openFDA | Refreshed May 5, 2026, 10:04 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed May 5, 2026, 10:04 AM UTC

Evidence

Reviewed / Updated / Sources

Reviewed by: Not available

Last reviewed: February 12, 2026

Updated: February 12, 2026, 10:44 PM UTC

Sources:
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Diazepam

Diazepam

Drug type: Generic ingredient • Generic profile • No FDA branded products linked

Both Liquid (Solution) Rx required 100% storefront ready

Species: Both

Manufacturer: Roche Vitamins, Inc.

Medication Snapshot

Merged from the current Roxee medication system with field-level provenance, freshness, and completeness tracking.

Diazepam

As a preanesthetic agent to reduce the amount of barbiturate required for short duration anesthesia. Species commonly shown: Both, Dog, No Use Class Stated Or Implied.

Generic name
Diazepam
Brand names
Veteeze® Injection
Manufacturer
Roche Vitamins, Inc.
Species
Both, Dog, No Use Class Stated Or Implied
Dosage forms
Liquid (Solution)
Prescription
Prescription required
Completeness
100%
Validation
Complete
Brand names
Veteeze® Injection
Dosage forms
Liquid (Solution)

Indications / Uses

As a preanesthetic agent to reduce the amount of barbiturate required for short duration anesthesia.

Warnings / Contraindications

Not for use in dogs with known sensitivity to benzodiazepines. Safety in animals intended for breeding and pregnant animals has not been established. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

  • Not for use in dogs with known sensitivity to benzodiazepines. Safety in animals intended for breeding and pregnant animals has not been established. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Side Effects

Top reported reactions (openFDA): Seizure NOS, Vomiting, Lethargy (see also Central nervous system depression in 'Neurological'), Death, Death by euthanasia, Ataxia.

FAQ

Both, Dog, No Use Class Stated Or Implied

Yes. Roxee shows this as prescription-only.

Liquid (Solution)

Source Transparency

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Pet Owner Quick Guide

Start here first for the safest next-step summary before the deeper medication detail.

Used for:

As a preanesthetic agent to reduce the amount of barbiturate required for short duration anesthesia.

Dosing note:

Exact dosing depends on your pet's species, weight, and health status. Use your veterinarian's instructions for the exact dose and schedule.

What to watch for:

  • Not for use in dogs with known sensitivity to benzodiazepines
  • Safety in animals intended for breeding and pregnant animals has not been established
  • wobbly/unsteady walking (1 reports)
  • Loss of appetite (1 reports)
  • Diarrhea (1 reports)

When to call the vet:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
  • Facial swelling or hives.
  • Blood in vomit or stool.

Regulatory restrictions are shown in Vet View.

What to tell or ask your vet today:

  • Is this medicine the right fit for my pet’s current symptoms?
  • Which warning signs mean I should call back right away?
  • How should I handle missed doses or refusal to take the medicine?
Major cautions & emergency warning signs

Side effects to monitor:

  • Not for use in dogs with known sensitivity to benzodiazepines
  • Safety in animals intended for breeding and pregnant animals has not been established
  • wobbly/unsteady walking
  • Loss of appetite
  • Diarrhea

Most reported reactions:

  • Unsteady walking (ataxia) (1 reports)
  • Loss of appetite (1 reports)
  • Diarrhea (1 reports)

Emergency warning signs:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
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Quick Facts

Official label facts first, then secondary summaries. Marketing content is separated below.

Species: Both
Manufacturer: Roche Vitamins, Inc.
Form: Liquid (Solution)
Identifiers:
NADA: 140848
Source metadata:

Warnings / Contraindications

Not for use in dogs with known sensitivity to benzodiazepines. Safety in animals intended for breeding and pregnant animals has not been established. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

  • High: Not for use in dogs with known sensitivity to benzodiazepines. Safety in animals intended for breeding and pregnant animals has not been established. Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Source metadata:

Adverse Reactions

Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.

Tap or hover a reaction to see what it means in plain language.

Tracked signals
32
Reported cases
32
Serious reports
31
Species represented
2
Grouped by Body System
Digestive (4) · Loss of appetite, Diarrhea, Decreased appetite Neurologic (1) · Unsteady walking (ataxia) Behavior (4) · Biting -aggression, Behavioral disorder (unspecified), Attention-seeking behaviour Other (23) · Dermatitis, Dehydration, Dehiscence
Most Reported Reactions
Reaction Body system Cases Species Serious cases
Neurologic 1 Dog 1
Digestive 1 Cat 1
Digestive 1 Cat 1
Other 1 Dog 1
Other 1 Cat 1
Other 1 Cat 1
Digestive 1 Cat 1
Other 1 Dog 1

Species coverage: Cat (17) Dog (15)

View detailed reaction table
Reaction Body system Species Seriousness Frequency Reports
Neurologic Dog Serious - 1
Digestive Cat Serious - 1
Digestive Cat Serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Digestive Cat Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Digestive Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Behavior Dog Serious - 1
Behavior Cat Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Behavior Cat Serious - 1
Other Dog Serious - 1
Other Cat Non-serious - 1
Behavior Cat Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Source metadata:

Documents

Owner handouts and official technical documents open on-page first, with the original source still one click away.

Owner handouts

0
No owner handouts linked yet.

Official label / PI

0
No official label or package insert links yet.

SPL

1

FOI

1

Veteeze® Injection

SPL · SPL

Open original
FDA Structured Product Label

Veteeze® Injection

Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.

Sponsor
Roche Vitamins, Inc.
NADA
140-848
Status
RX
Form
Liquid (Solution)
Route
Intravenous
Species
Dog, No Use Class Stated Or Implied
Composition / specifications
Each milliliter of sterile solution contains 5 milligrams of diazepam.

Dogs

Indication
As a preanesthetic agent to reduce the amount of barbiturate required for short duration anesthesia.
Dosage
Intravenously, 0.2 milligram per kilogram of body weight 3-5 minutes before anesthesia is to be induced using a short acting barbiturate.
Limitations
Not for use in dogs with known sensitivity to benzodiazepines. Safety in animals intended for breeding and pregnant animals has not been established. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

N140848_Orig_12_17_1992.pdf

FOI · FOI

Open original
Source metadata:
Veterinary reference (advanced)

Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.

At a Glance

Quick facts and links to official labeling and safety signals.

Data freshness
  • Storefront facts: Source Roxee | Refreshed May 5, 2026, 10:00 AM UTC
    The storefront fact projection used for browse cards and quick facts.
  • Animal Drugs @ FDA: Source FDA | Refreshed May 5, 2026, 10:00 AM UTC
    Applications/products are imported from FDA export data.
  • Animal Drugs @ FDA previews: Source FDA | Refreshed Feb 9, 2026, 3:05 AM UTC
    Label highlights/doc links are fetched from FDA preview endpoints.
  • openFDA reaction terms: Source FDA openFDA | Refreshed May 5, 2026, 10:04 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed May 5, 2026, 10:04 AM UTC
Official (FDA)
Identity: Generic ingredient • No FDA branded products linked
No official FDA brand rows linked yet for this ingredient.
Case-reported brands (openFDA): MSK
Catalog species: Both • FDA-labeled species: Dog
Rx/OTC: RX
Form/route: Liquid (Solution) • Intravenous
Applications: NADA 140-848
Documents: 1 (FOI: 1) • SPL: 1 • Label highlights • Official documents
Safety (openFDA)
Top reactions: Dog 16 • Cat 35 • View
Case summaries: 9 (showing 8) • View
openFDA reports are unverified and do not prove causation.
Diagnosis Codes

Diagnosis-code mappings are not available for this medication yet.

Counseling and Monitoring Highlights

Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.

Owner-facing counseling points
  • Not for use in dogs with known sensitivity to benzodiazepines. Safety in animals intended for breeding and pregnant animals has not been established. Federal law restricts this drug to use by or on the order of a licensed veterinarian. (Contraindication, High)
Top reaction signals
Unsteady walking (ataxia) (1) Loss of appetite (1) Diarrhea (1) Dermatitis (1) Dehydration (1) Dehiscence (1) Decreased appetite (1) Decreased activity (1)

Identifiers & Packages

Normalized identifiers (NDC/NADA/ANADA) and package metadata from regulator listings.

Identifiers
NADA: 140848

Enriched Documents

Documents are tiered by source trust: Official, Clinical, Manufacturer, Marketing.

Data Sources & Change Log

Every non-trivial field is expected to include provenance and update timestamps.

Official 9 Clinical 1 Manufacturer 0 Marketing 0
Current Field Facts
  • side_effects: Top reported reactions (openFDA): Seizure NOS, Vomiting, Lethargy (see also Central nervous system depression in 'Neurological'), Death, Death by euthanasia, A… (Clinical, 2026-04-11)
  • contraindications: Not for use in dogs with known sensitivity to benzodiazepines. Safety in animals intended for breeding and pregnant animals has not been established. Federal l… (Official, 2026-04-12)
  • contraindications: Not for use in dogs with known sensitivity to benzodiazepines. Safety in animals intended for breeding and pregnant animals has not been established. Federal l… (Official, 2026-04-11)
  • contraindications: Not for use in dogs with known sensitivity to benzodiazepines. Safety in animals intended for breeding and pregnant animals has not been established. Federal l… (Official, 2026-02-12)
  • side_effects: Top reported reactions (openFDA): Seizure NOS, Vomiting, Lethargy (see also Central nervous system depression in 'Neurological'), Death, Death by euthanasia, A… (Official, 2026-04-12)
  • side_effects: Top reported reactions (openFDA): Seizure NOS, Vomiting, Lethargy (see also Central nervous system depression in 'Neurological'), Death, Death by euthanasia, A… (Official, 2026-02-12)
  • usage: As a preanesthetic agent to reduce the amount of barbiturate required for short duration anesthesia. (Official, 2026-04-12)
  • usage: As a preanesthetic agent to reduce the amount of barbiturate required for short duration anesthesia. (Official, 2026-04-11)
  • usage: As a preanesthetic agent to reduce the amount of barbiturate required for short duration anesthesia. (Official, 2026-02-12)
Recent Revisions
  • side_effects updated 2026-04-12 10:05 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-04-12 10:05 by etl_backfill • Backfilled from existing medication fields
  • usage updated 2026-04-12 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-04-11 10:05 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-04-11 10:05 by etl_backfill • Backfilled from existing medication fields
  • usage updated 2026-04-11 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields
  • usage updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields

FDA Products & Applications (Animal Drugs @ FDA)

Official sponsor/proprietary-name/application-status records linked by active ingredient.

Product Sponsor Application Status Published
Veteeze® Injection
RX
Diazepam
Liquid (Solution) • Intravenous
Label highlights
Official documents
Roche Vitamins, Inc. NADA 140-848 W Aug 24, 2017

Data source: FDA Animal Drugs @ FDA (public search export).

What It's For (FDA Label Highlights)

Extracted from FDA Animal Drugs @ FDA product labeling. Always confirm details with your veterinarian.

Species: Dog, No Use Class Stated Or Implied
Composition / specifications
Each milliliter of sterile solution contains 5 milligrams of diazepam.
Dogs
Indication
As a preanesthetic agent to reduce the amount of barbiturate required for short duration anesthesia.
Dosage
Intravenously, 0.2 milligram per kilogram of body weight 3-5 minutes before anesthesia is to be induced using a short acting barbiturate.
Limitations
Not for use in dogs with known sensitivity to benzodiazepines. Safety in animals intended for breeding and pregnant animals has not been established. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

FDA page: Open in Animal Drugs @ FDA

Usage

As a preanesthetic agent to reduce the amount of barbiturate required for short duration anesthesia.

Source: FDA Animal Drugs @ FDA • Reference

Contraindications

Not for use in dogs with known sensitivity to benzodiazepines. Safety in animals intended for breeding and pregnant animals has not been established. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Top Reported Reactions (openFDA)

De-duplicated reaction terms grouped by body system from FDA openFDA reports (not verified; does not prove causation).

Digestive
Loss of appetite (1) • Cat Diarrhea (1) • Cat Decreased appetite (1) • Cat Bloody diarrhoea (1) • Dog

Showing top 5 for Digestive.

Neurologic
Unsteady walking (1) • Dog

Showing top 5 for Neurologic.

Behavior
Biting -aggression (1) • Dog Behavioral disorder (1) • Cat Attention-seeking behaviour (1) • Cat Anxiety (1) • Cat

Showing top 5 for Behavior.

Other
Dermatitis (1) • Dog Dehydration (1) • Cat Dehiscence (1) • Cat Decreased activity (1) • Dog Death (1) • Dog
Show more (18)
Deafness (1) • Cat Constricted pupils (1) • Dog Conjunctival oedema (1) • Cat Chattering of teeth (1) • Cat Blood loss NOS (1) • Dog Blindness (1) • Dog Basophilia (1) • Cat Balance problem (1) • Cat Asphyxia (1) • Dog Arthritis (1) • Cat Anaphylaxis (1) • Cat Administration error NOS (1) • Cat Abnormal ultrasound finding (1) • Dog Abnormal radiograph finding (1) • Cat Abnormal pupil light reflex (1) • Dog Abnormal posture NOS (1) • Dog Abnormal menace reflex test (1) • Dog Abdominal pain (1) • Dog

Showing top 5 for Other.

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Adverse Event Case Summaries (openFDA)

These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.

Dog, Dog (other), Female, 1.5 year, 21.32 kilogram • Drug: MSK, Intravenous • Reactions: Seizure NOS, Blindness, Asphyxia, Death • Outcome: Died

  • Report ID: USA-USFDACVM-2025-US-075227
  • Serious AE: Yes
  • Treated For AE: No
  • Sex: Female
  • Age: 1.50 Year
  • Weight: 21.320 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Intravenous
Reactions Reported:
Seizure NOS Blindness Asphyxia Death
Outcomes: Died

Dog, ['Retriever - Golden', 'Poodle - Standard'], Male, 7 year, 43.273 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Thrombocytopenia, Blood loss NOS, Skin petechiae, Death • Outcome: Died

  • Report ID: USA-USFDACVM-2025-US-074431
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 7.00 Year
  • Weight: 43.273 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Unassigned
Reactions Reported:
Thrombocytopenia Blood loss NOS Skin petechiae Death
Outcomes: Died

Cat, Domestic Mediumhair, Female, 2 year, 4.13 kilogram • Drug: MSK, Unknown • Reactions: Loss of appetite, Reluctant to move, Vocalisation, Loss of bowel control, Not urinating… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-074528
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 2.00 Year
  • Weight: 4.130 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Loss of appetite Reluctant to move Vocalisation Loss of bowel control Not urinating Eosinopenia Basophilia Hypernatremia Thrombocytopenia Abnormal radiograph finding Third eyelid protrusion Other ear disorder NOS
Outcomes: Ongoing

Cat, Domestic Mediumhair, Female, 2 year, 4.13 kilogram • Drug: MSK, Unknown • Reactions: Reluctant to move, Vocalisation, Loss of bowel control, Not urinating, Eosinopenia… • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-072580
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 2.00 Year
  • Weight: 4.130 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Reluctant to move Vocalisation Loss of bowel control Not urinating Eosinopenia Basophilia Hypernatremia Thrombocytopenia Abnormal radiograph finding Third eyelid protrusion Other ear disorder NOS Nasal discharge Falling
Outcomes: Outcome Unknown

Cat, Domestic Mediumhair, Female, 2 year, 4.13 kilogram • Drug: MSK, Unknown • Reactions: Loss of appetite, Reluctant to move, Vocalisation, Loss of bowel control, Not urinating… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-068768
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 2.00 Year
  • Weight: 4.130 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Loss of appetite Reluctant to move Vocalisation Loss of bowel control Not urinating Eosinopenia Basophilia Hypernatremia Thrombocytopenia Abnormal radiograph finding Third eyelid protrusion Other ear disorder NOS
Outcomes: Ongoing

Cat, Domestic Shorthair, Female, 7 year, 3.8 kilogram • Drug: MSK • Reactions: Balance problem, Muscle tremor, Deafness, Not eating, Not drinking… • Outcome: Recovered with Sequela

  • Report ID: USA-USFDACVM-2025-US-071642
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 7.00 Year
  • Weight: 3.800 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
Reactions Reported:
Balance problem Muscle tremor Deafness Not eating Not drinking Irritability Vocalisation Anxiety Head shake - ear disorder Scratching Ear discharge Neurological disorder NOS
Outcomes: Recovered with Sequela

Dog, ['Retriever - Labrador', 'Dog (unknown)'], Female, 3 year, 18.144 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Vocalisation, Pain NOS, Limb non-weight bearing, Not eating, Not drinking… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-065439
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 3.00 Year
  • Weight: 18.144 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Unassigned
Reactions Reported:
Vocalisation Pain NOS Limb non-weight bearing Not eating Not drinking Biting -aggression Stiffness NOS Reluctant to move Abnormal posture NOS
Outcomes: Ongoing

Cat, Domestic Mediumhair, Male, 14.6 year, 5 kilogram • Drug: MSK, Unknown • Reactions: Not eating, Limping, Low sodium-potassium ratio, Elevated alanine aminotransferase, Gait abnormality… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-066416
  • Serious AE: No
  • Treated For AE: Yes
  • Sex: Male
  • Age: 14.60 Year
  • Weight: 5.000 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Not eating Limping Low sodium-potassium ratio Elevated alanine aminotransferase Gait abnormality Hard stool Skin inflammation NOS Arthritis Swelling NOS
Outcomes: Ongoing

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Overdose Information

No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.

Storage & Handling

No approved storage guidance is linked yet for this ingredient. Use manufacturer packaging and veterinary guidance for handling/storage.

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