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Roxee Meds Catalog

Emodepside, Praziquantel

Medication catalog facts with explicit FDA-approval, off-label, source-limited, and safety context.

Both Catalog complete FDA data linked Rx required Liquid Elanco US Inc. Official label facts Owner quick guide first
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Data freshness

Storefront facts
Catalog refreshed
Apr 22, 2026, 10:06 a.m.

These are the storefront facts Roxee uses on browse cards and quick facts.

FDA applications
FDA application data refreshed
May 5, 2026, 10:00 a.m.

Sponsor, product, and application records imported from Animal Drugs @ FDA.

Safety reports
Safety data refreshed
May 5, 2026, 10:01 a.m.

openFDA reaction terms and case summaries are supporting evidence, not proof of causality.

Source timing details
Source timing details
  • Storefront facts: Source Roxee | Refreshed Apr 22, 2026, 10:06 AM UTC
    The storefront fact projection used for browse cards and quick facts.
  • Animal Drugs @ FDA: Source FDA | Refreshed May 5, 2026, 10:00 AM UTC
    Applications/products are imported from FDA export data.
  • Animal Drugs @ FDA previews: Source FDA | Refreshed Feb 9, 2026, 3:05 AM UTC
    Label highlights/doc links are fetched from FDA preview endpoints.
  • openFDA reaction terms: Source FDA openFDA | Refreshed May 5, 2026, 10:04 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed May 5, 2026, 10:04 AM UTC

Evidence

Reviewed / Updated / Sources

Reviewed by: Not available

Last reviewed: April 22, 2026

Updated: April 22, 2026, 10:06 AM UTC

Sources:
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Emodepside, Praziquantel

Emodepside, Praziquantel

Drug type: Generic ingredient • Generic profile • No FDA branded products linked

Both Liquid Rx required 100% storefront ready

Species: Both

Manufacturer: Elanco US Inc.

Medication Snapshot

Merged from the current Roxee medication system with field-level provenance, freshness, and completeness tracking.

Emodepside, Praziquantel

For the treatment and control of hookworm infections caused by Ancylostoma tubaeforme (adults, immature adults, and fourth stage larvae), roundworm infections caused by Toxocara cati (adults and fourth stage larvae), and tapeworm infections caused by Dipylidium caninum (adults) and Taenia taeniaeformis (adults). Species commonly shown: Both, Cat, No Use Class Stated Or Implied.

Generic name
Emodepside, Praziquantel
Brand names
Profender™
Manufacturer
Elanco US Inc.
Species
Both, Cat, No Use Class Stated Or Implied
Dosage forms
Liquid
Prescription
Prescription required
Completeness
100%
Validation
Complete
Brand names
Profender™
Dosage forms
Liquid

Indications / Uses

For the treatment and control of hookworm infections caused by Ancylostoma tubaeforme (adults, immature adults, and fourth stage larvae), roundworm infections caused by Toxocara cati (adults and fourth stage larvae), and tapeworm infections caused by Dipylidium caninum (adults) and Taenia taeniaeformis (adults).

Warnings / Contraindications

Federal law restricts this drug to use by or on the order of a licensed veterinarian. Safe use of this product has not been evaluated in cats less that 8 weeks of age or weighing less than 2.2 lbs (1 kg), in cats used for breeding, during pregnancy, or in lactating queens. Oral ingestion or exposure should be avoided.

  • Federal law restricts this drug to use by or on the order of a licensed veterinarian. Safe use of this product has not been evaluated in cats less that 8 weeks of age or weighing less than 2.2 lbs (1 kg), in cats used for breeding, during pregnancy, or in lactating queens. Oral ingestion or exposure should be avoided.

Side Effects

Top reported reactions (openFDA): Lack of efficacy (endoparasite) - hookworm, Arched back, Decreased appetite, Elevated globulins, Febrile, Hypokalaemia.

FAQ

Both, Cat, No Use Class Stated Or Implied

Yes. Roxee shows this as prescription-only.

Liquid

Related Conditions

Pica

Source Transparency

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Pet Owner Quick Guide

Start here first for the safest next-step summary before the deeper medication detail.

Used for:

For the treatment and control of hookworm infections caused by Ancylostoma tubaeforme (adults, immature adults, and fourth stage larvae), roundworm infections caused by Toxocara cati (adults and fourth stage larvae), and...

Dosing note:

Exact dosing depends on your pet's species, weight, and health status. Use your veterinarian's instructions for the exact dose and schedule.

What to watch for:

  • Safe use of this product has not been evaluated in cats less that 8 weeks of age or weighing less than 2.2 lbs (1 kg), in cats used for breeding, during pregnancy, or in lactating queens
  • Oral ingestion or exposure should be avoided
  • Hypokalaemia (1 reports)
  • Hissing (1 reports)
  • Grand mal seizure (1 reports)

When to call the vet:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
  • Facial swelling or hives.
  • Blood in vomit or stool.

Regulatory restrictions are shown in Vet View.

What to tell or ask your vet today:

  • Is this medicine the right fit for my pet’s current symptoms?
  • Which warning signs mean I should call back right away?
  • How should I handle missed doses or refusal to take the medicine?
Major cautions & emergency warning signs

Side effects to monitor:

  • Safe use of this product has not been evaluated in cats less that 8 weeks of age or weighing less than 2.2 lbs (1 kg), in cats used for breeding, during pregnancy, or in lactating queens
  • Oral ingestion or exposure should be avoided
  • Hypokalaemia
  • Hissing
  • Grand mal seizure

Most reported reactions:

  • Hypokalaemia (1 reports)
  • Hissing (1 reports)
  • Grand mal seizure (1 reports)

Emergency warning signs:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
Talk to a Vet / Find a Vet Near You Start Symptom Intake

Quick Facts

Official label facts first, then secondary summaries. Marketing content is separated below.

Species: Both
Manufacturer: Elanco US Inc.
Form: Liquid
Identifiers:
NADA: 141275
Source metadata:

Warnings / Contraindications

Federal law restricts this drug to use by or on the order of a licensed veterinarian. Safe use of this product has not been evaluated in cats less that 8 weeks of age or weighing less than 2.2 lbs (1 kg), in cats used for breeding, during pregnancy, or in lactating queens. Oral ingestion or exposure should be avoided.

  • High: Federal law restricts this drug to use by or on the order of a licensed veterinarian. Safe use of this product has not been evaluated in cats less that 8 weeks of age or weighing less than 2.2 lbs (1 kg), in cats used for breeding, during pregnancy, or in lactating queens. Oral ingestion or exposure should be avoided.
Source metadata:

Adverse Reactions

Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.

Tap or hover a reaction to see what it means in plain language.

Tracked signals
32
Reported cases
32
Serious reports
20
Species represented
1
Grouped by Body System
Digestive (3) · Loss of appetite, Decreased appetite, Bloody diarrhoea Skin & allergy (1) · Application site hair loss Neurologic (2) · Unsteady walking (ataxia), Grand mal seizure Behavior (1) · Behavioral disorder (unspecified) Other (25) · Inappropriate urination, Hypokalaemia, Hyperproteinaemia
Most Reported Reactions
Reaction Body system Cases Species Serious cases
Other 1 Cat 1
Other 1 Cat 1
Neurologic 1 Cat 1
Other 1 Cat 1
Other 1 Cat 1
Other 1 Cat 1
Other 1 Cat 1
Other 1 Cat 1

Species coverage: Cat (32)

View detailed reaction table
Reaction Body system Species Seriousness Frequency Reports
Neurologic Cat Non-serious - 1
Digestive Cat Non-serious - 1
Other Cat Non-serious - 1
Other Cat Serious - 1
Other Cat Non-serious - 1
Other Cat Serious - 1
Other Cat Non-serious - 1
Neurologic Cat Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Cat Non-serious - 1
Other Cat Non-serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Digestive Cat Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Digestive Cat Serious - 1
Behavior Cat Serious - 1
Other Cat Serious - 1
Other Cat Non-serious - 1
Skin & allergy Cat Non-serious - 1
Other Cat Non-serious - 1
Other Cat Non-serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Cat Non-serious - 1
Source metadata:

Documents

Owner handouts and official technical documents open on-page first, with the original source still one click away.

Owner handouts

0
No owner handouts linked yet.

Official label / PI

0
No official label or package insert links yet.

SPL

1

FOI

1

Profender™

SPL · SPL

Open original
FDA Structured Product Label

Profender™

Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.

Sponsor
Elanco US Inc.
NADA
141-275
Status
RX
Form
Liquid
Route
Topical
Species
Cat, No Use Class Stated Or Implied
Composition / specifications
Each mL contains 21.4 mg emodepside and 85.7 mg praziquantel

Cats

Indication
For the treatment and control of hookworm infections caused by Ancylostoma tubaeforme (adults, immature adults, and fourth stage larvae), roundworm infections caused by Toxocara cati (adults and fourth stage larvae), and tapeworm infections caused by Dipylidium caninum (adults) and Taenia taeniaeformis (adults).
Dosage
The recommended minimum dose is 1.36 mg/pound (lb) (3 mg/kilogram (kg)) emodepside and 5.45 mg/ lb (12 mg/kg) praziquantel applied as a single topical dose.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian. Safe use of this product has not been evaluated in cats less that 8 weeks of age or weighing less than 2.2 lbs (1 kg), in cats used for breeding, during pregnancy, or in lactating queens. Oral ingestion or exposure should be avoided.

ucm062332.pdf

FOI · FOI

Open original
Source metadata:
Veterinary reference (advanced)

Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.

At a Glance

Quick facts and links to official labeling and safety signals.

Data freshness
  • Storefront facts: Source Roxee | Refreshed Apr 22, 2026, 10:06 AM UTC
    The storefront fact projection used for browse cards and quick facts.
  • Animal Drugs @ FDA: Source FDA | Refreshed May 5, 2026, 10:00 AM UTC
    Applications/products are imported from FDA export data.
  • Animal Drugs @ FDA previews: Source FDA | Refreshed Feb 9, 2026, 3:05 AM UTC
    Label highlights/doc links are fetched from FDA preview endpoints.
  • openFDA reaction terms: Source FDA openFDA | Refreshed May 5, 2026, 10:04 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed May 5, 2026, 10:04 AM UTC
Official (FDA)
Identity: Generic ingredient • No FDA branded products linked
No official FDA brand rows linked yet for this ingredient.
Case-reported brands (openFDA): MSK
Catalog species: Both • FDA-labeled species: Cat
Rx/OTC: RX
Form/route: Liquid • Topical
Applications: NADA 141-275
Documents: 1 (FOI: 1) • SPL: 1 • Label highlights • Official documents
Safety (openFDA)
Top reactions: Dog 0 • Cat 50 • View
Case summaries: 11 (showing 8) • View
openFDA reports are unverified and do not prove causation.
Explore
Related conditions: Pica
Linked using: Fda_Label (0.95)
Diagnosis Codes

Diagnosis-code mappings are not available for this medication yet.

Counseling and Monitoring Highlights

Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.

Owner-facing counseling points
  • Federal law restricts this drug to use by or on the order of a licensed veterinarian. Safe use of this product has not been evaluated in cats less that 8 weeks of age or weighing less than 2.2 lbs (1 kg), in cats used for breeding, during pregnancy, or in lactating queens. Oral ingestion or exposure should be avoided. (Contraindication, High)
Top reaction signals
Hypokalaemia (1) Hissing (1) Grand mal seizure (1) Gingivitis (1) Fibrosarcoma (1) Fever (1) Febrile (1) Dysphoria (1)

Identifiers & Packages

Normalized identifiers (NDC/NADA/ANADA) and package metadata from regulator listings.

Identifiers
NADA: 141275

Enriched Documents

Documents are tiered by source trust: Official, Clinical, Manufacturer, Marketing.

  • ucm062332.pdf • FOI summary • Official • April 29, 2021
    FDA FOI summary for application 141275

Data Sources & Change Log

Every non-trivial field is expected to include provenance and update timestamps.

Official 21 Clinical 6 Manufacturer 0 Marketing 0
Current Field Facts
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-21)
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-20)
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-19)
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-17)
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-16)
  • side_effects: Top reported reactions (openFDA): Lack of efficacy (endoparasite) - hookworm, Arched back, Decreased appetite, Elevated globulins, Febrile, Hypokalaemia. (Clinical, 2026-04-11)
  • contraindications: Federal law restricts this drug to use by or on the order of a licensed veterinarian. Safe use of this product has not been evaluated in cats less that 8 weeks… (Official, 2026-04-22)
  • indications: PROFENDER Topical Solution is indicated for the treatment and control of hookworm infections caused by Ancylostoma tubaeforme (adults, immature adults, and fou… (Official, 2026-05-05)
  • indications: PROFENDER Topical Solution is indicated for the treatment and control of hookworm infections caused by Ancylostoma tubaeforme (adults, immature adults, and fou… (Official, 2026-05-03)
  • indications: PROFENDER Topical Solution is indicated for the treatment and control of hookworm infections caused by Ancylostoma tubaeforme (adults, immature adults, and fou… (Official, 2026-05-02)
  • indications: PROFENDER Topical Solution is indicated for the treatment and control of hookworm infections caused by Ancylostoma tubaeforme (adults, immature adults, and fou… (Official, 2026-04-29)
  • indications: PROFENDER Topical Solution is indicated for the treatment and control of hookworm infections caused by Ancylostoma tubaeforme (adults, immature adults, and fou… (Official, 2026-04-28)
  • indications: PROFENDER Topical Solution is indicated for the treatment and control of hookworm infections caused by Ancylostoma tubaeforme (adults, immature adults, and fou… (Official, 2026-04-27)
  • indications: PROFENDER Topical Solution is indicated for the treatment and control of hookworm infections caused by Ancylostoma tubaeforme (adults, immature adults, and fou… (Official, 2026-04-26)
  • indications: PROFENDER Topical Solution is indicated for the treatment and control of hookworm infections caused by Ancylostoma tubaeforme (adults, immature adults, and fou… (Official, 2026-04-25)
  • indications: PROFENDER Topical Solution is indicated for the treatment and control of hookworm infections caused by Ancylostoma tubaeforme (adults, immature adults, and fou… (Official, 2026-04-22)
  • side_effects: Top reported reactions (openFDA): Lack of efficacy (endoparasite) - hookworm, Arched back, Decreased appetite, Elevated globulins, Febrile, Hypokalaemia. (Official, 2026-04-22)
  • side_effects: Top reported reactions (openFDA): Lack of efficacy (endoparasite) - hookworm, Arched back, Decreased appetite, Elevated globulins, Febrile, Hypokalaemia. (Official, 2026-04-17)
  • side_effects: Top reported reactions (openFDA): Lack of efficacy (endoparasite) - hookworm, Arched back, Decreased appetite, Elevated globulins, Febrile, Hypokalaemia. (Official, 2026-04-15)
  • side_effects: Top reported reactions (openFDA): Lack of efficacy (endoparasite) - hookworm, Arched back, Decreased appetite, Elevated globulins, Febrile, Hypokalaemia. (Official, 2026-02-12)
Recent Revisions
  • side_effects updated 2026-04-22 10:06 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-04-22 10:06 by etl_backfill • Backfilled from existing medication fields
  • usage updated 2026-04-22 10:06 by etl_backfill • Backfilled from existing medication fields
  • monitoring updated 2026-04-21 10:07 by curated_loader • Clinical monitoring context for feline diabetes management.
  • usage updated 2026-04-21 10:07 by curated_loader • Usage statement from FDA warning letter and approved-product context.
  • drug_profile_type updated 2026-04-21 10:07 by curated_loader • FDA source confirms Senvelgo as a branded approved product.
  • manufacturer_name updated 2026-04-21 10:07 by curated_loader • FDA warning letter identifies the approved sponsor/manufacturer.
  • brand_names updated 2026-04-21 10:07 by curated_loader • FDA warning letter references Senvelgo as the approved animal drug.
  • approval_reference updated 2026-04-21 10:07 by curated_loader • Official FDA application reference for Senvelgo.
  • monitoring updated 2026-04-20 10:09 by curated_loader • Clinical monitoring context for feline diabetes management.
  • usage updated 2026-04-20 10:09 by curated_loader • Usage statement from FDA warning letter and approved-product context.
  • drug_profile_type updated 2026-04-20 10:09 by curated_loader • FDA source confirms Senvelgo as a branded approved product.
  • manufacturer_name updated 2026-04-20 10:09 by curated_loader • FDA warning letter identifies the approved sponsor/manufacturer.
  • brand_names updated 2026-04-20 10:09 by curated_loader • FDA warning letter references Senvelgo as the approved animal drug.
  • approval_reference updated 2026-04-20 10:09 by curated_loader • Official FDA application reference for Senvelgo.
  • monitoring updated 2026-04-19 10:08 by curated_loader • Clinical monitoring context for feline diabetes management.
  • usage updated 2026-04-19 10:08 by curated_loader • Usage statement from FDA warning letter and approved-product context.
  • drug_profile_type updated 2026-04-19 10:08 by curated_loader • FDA source confirms Senvelgo as a branded approved product.
  • manufacturer_name updated 2026-04-19 10:08 by curated_loader • FDA warning letter identifies the approved sponsor/manufacturer.
  • brand_names updated 2026-04-19 10:08 by curated_loader • FDA warning letter references Senvelgo as the approved animal drug.

FDA Products & Applications (Animal Drugs @ FDA)

Official sponsor/proprietary-name/application-status records linked by active ingredient.

Product Sponsor Application Status Published
Profender™
RX
Emodepside Praziquantel
Liquid • Topical
Label highlights
Official documents
Elanco US Inc. NADA 141-275 Approved Apr 29, 2021

Data source: FDA Animal Drugs @ FDA (public search export).

What It's For (FDA Label Highlights)

Extracted from FDA Animal Drugs @ FDA product labeling. Always confirm details with your veterinarian.

Species: Cat, No Use Class Stated Or Implied
Composition / specifications
Each mL contains 21.4 mg emodepside and 85.7 mg praziquantel
Cats
Indication
For the treatment and control of hookworm infections caused by Ancylostoma tubaeforme (adults, immature adults, and fourth stage larvae), roundworm infections caused by Toxocara cati (adults and fourth stage larvae), and tapeworm infections caused by Dipylidium caninum (adults) and Taenia taeniaeformis (adults).
Dosage
The recommended minimum dose is 1.36 mg/pound (lb) (3 mg/kilogram (kg)) emodepside and 5.45 mg/ lb (12 mg/kg) praziquantel applied as a single topical dose.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian. Safe use of this product has not been evaluated in cats less that 8 weeks of age or weighing less than 2.2 lbs (1 kg), in cats used for breeding, during pregnancy, or in lactating queens. Oral ingestion or exposure should be avoided.

FDA page: Open in Animal Drugs @ FDA

Usage

For the treatment and control of hookworm infections caused by Ancylostoma tubaeforme (adults, immature adults, and fourth stage larvae), roundworm infections caused by Toxocara cati (adults and fourth stage larvae), and tapeworm infections caused by Dipylidium caninum (adults) and Taenia taeniaeformis (adults).

Source: FDA Animal Drugs @ FDA • Reference

Contraindications

Federal law restricts this drug to use by or on the order of a licensed veterinarian. Safe use of this product has not been evaluated in cats less that 8 weeks of age or weighing less than 2.2 lbs (1 kg), in cats used for breeding, during pregnancy, or in lactating queens. Oral ingestion or exposure should be avoided.

Top Reported Reactions (openFDA)

De-duplicated reaction terms grouped by body system from FDA openFDA reports (not verified; does not prove causation).

Digestive
Loss of appetite (1) • Cat Decreased appetite (1) • Cat Bloody diarrhoea (1) • Cat

Showing top 5 for Digestive.

Skin & allergy
Application site hair loss (1) • Cat

Showing top 5 for Skin & allergy.

Neurologic
Unsteady walking (1) • Cat Grand mal seizure (1) • Cat

Showing top 5 for Neurologic.

Behavior
Behavioral disorder (1) • Cat

Showing top 5 for Behavior.

Other
Inappropriate urination (1) • Cat Hypokalaemia (1) • Cat Hyperproteinaemia (1) • Cat Hissing (1) • Cat Hiding (1) • Cat
Show more (20)
Gingivitis (1) • Cat Fibrosarcoma (1) • Cat Fever (1) • Cat Febrile (1) • Cat Falling (1) • Cat Elevated globulins (1) • Cat Dysphoria (1) • Cat Dilated pupils (1) • Cat Dehydration (1) • Cat Decreased haemoglobin (1) • Cat Decreased haematocrit (1) • Cat Decreased activity (1) • Cat Death (1) • Cat Arched back (1) • Cat Application site reddening (1) • Cat Application site bleeding (1) • Cat Accidental exposure (1) • Cat Abnormal radiograph finding (1) • Cat Abnormal cytology (1) • Cat Abdominal discomfort (1) • Cat

Showing top 5 for Other.

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Adverse Event Case Summaries (openFDA)

These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.

Cat, Domestic Shorthair, Male, 9.5 year, 5.09 kilogram • Drug: MSK, Solution, Topical, Dose: 1 dose per animal • Reactions: Application site hair loss, Application site bleeding, Application site reddening • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-075004
  • Serious AE: No
  • Treated For AE: No
  • Sex: Male
  • Age: 9.50 Year
  • Weight: 5.090 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Topical
  • Form: Solution
  • Dose: 1 dose per animal
Reactions Reported:
Application site hair loss Application site bleeding Application site reddening
Outcomes: Outcome Unknown

Cat, Domestic Shorthair, Male, 24 week, 4.71 kilogram • Drug: MSK, Solution, Topical, Dose: 1 tube per animal • Reactions: Lack of efficacy (endoparasite) - tapeworm, Nasal discharge, Lack of efficacy (ectoparasite) - flea • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-075058
  • Serious AE: No
  • Treated For AE: No
  • Sex: Male
  • Age: 24.00 Week
  • Weight: 4.710 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Topical
  • Form: Solution
  • Dose: 1 tube per animal
Reactions Reported:
Lack of efficacy (endoparasite) - tapeworm Nasal discharge Lack of efficacy (ectoparasite) - flea
Outcomes: Outcome Unknown

Cat, Domestic Shorthair, Male, 1 year, 4.536 kilogram • Drug: MSK, Solution, Topical, Dose: 1 tube per animal • Reactions: Behavioral disorder (unspecified), Loss of appetite, Tiredness (lethargy), Abdominal discomfort • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-074626
  • Serious AE: No
  • Treated For AE: Yes
  • Sex: Male
  • Age: 1.00 Year
  • Weight: 4.536 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Topical
  • Form: Solution
  • Dose: 1 tube per animal
Reactions Reported:
Behavioral disorder (unspecified) Loss of appetite Tiredness (lethargy) Abdominal discomfort
Outcomes: Outcome Unknown

Cat, Domestic Shorthair, Male, 8 week, 1.2 kilogram • Drug: MSK, Solution, Oral, Dose: 1 tube per animal • Reactions: Accidental exposure, Tremors, Tiredness (lethargy) • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-073542
  • Serious AE: No
  • Treated For AE: Yes
  • Sex: Male
  • Age: 8.00 Week
  • Weight: 1.200 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Solution
  • Dose: 1 tube per animal
Reactions Reported:
Accidental exposure Tremors Tiredness (lethargy)
Outcomes: Outcome Unknown

Cat, Domestic Shorthair, Female, 7 year, 3.3 kilogram • Drug: MSK, Solution, Topical, Dose: 1 dose per animal • Reactions: Unsteady walking (ataxia), Tiredness (lethargy), Wobbliness, Falling, Elevated globulins… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-073974
  • Serious AE: No
  • Treated For AE: Yes
  • Sex: Female
  • Age: 7.00 Year
  • Weight: 3.300 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Topical
  • Form: Solution
  • Dose: 1 dose per animal
Reactions Reported:
Unsteady walking (ataxia) Tiredness (lethargy) Wobbliness Falling Elevated globulins Neutrophilia Low serum alkaline phosphatase Hyperproteinaemia
Outcomes: Ongoing

Cat, Domestic Mediumhair, Female, 6.08 year, 4.82 kilogram • Drug: MSK, Solution, Unknown • Reactions: Fibrosarcoma, Decreased activity, Hissing, Injection site lump, Behavioral disorder (unspecified)… • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-070682
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 6.08 Year
  • Weight: 4.820 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Solution
Reactions Reported:
Fibrosarcoma Decreased activity Hissing Injection site lump Behavioral disorder (unspecified) Tooth disorder Gingivitis Neoplasia NOS Leucocytosis NOS Skin inflammation NOS Abnormal radiograph finding Abnormal cytology
Outcomes: Outcome Unknown

Cat, Domestic Shorthair, Female, 9 year, 3.83 kilogram • Drug: MSK, Solution, Topical, Dose: 1 dose per animal • Reactions: Not eating, Less social, Reluctant to move, Hiding, Not drinking • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2025-US-069698
  • Serious AE: No
  • Treated For AE: No
  • Sex: Female
  • Age: 9.00 Year
  • Weight: 3.830 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Topical
  • Form: Solution
  • Dose: 1 dose per animal
Reactions Reported:
Not eating Less social Reluctant to move Hiding Not drinking
Outcomes: Recovered/Normal

Cat, Domestic Shorthair, Female, 3.58 year, 6.21 kilogram • Drug: MSK, Solution, Topical, Dose: 1 dose per animal • Reactions: Lack of efficacy (endoparasite) - tapeworm • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-068009
  • Serious AE: No
  • Treated For AE: No
  • Sex: Female
  • Age: 3.58 Year
  • Weight: 6.210 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Topical
  • Form: Solution
  • Dose: 1 dose per animal
Reactions Reported:
Lack of efficacy (endoparasite) - tapeworm
Outcomes: Outcome Unknown

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Overdose Information

No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.

Storage & Handling

No approved storage guidance is linked yet for this ingredient. Use manufacturer packaging and veterinary guidance for handling/storage.

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