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Roxee Medication Guide

Etodolac

Medication reference facts with explicit FDA-approval, off-label, source-limited, and safety context. Roxee does not sell, prescribe, or dispense medications.

Both Reference complete FDA data linked Rx required Tablet Boehringer Ingelheim Animal Health USA Inc. Official label facts Owner quick guide first
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Data freshness

Reference facts
Reference refreshed
Jun 22, 2026, 10:40 a.m.

These are the reference facts Roxee uses on browse cards and quick facts.

FDA applications
FDA application data refreshed
Jun 22, 2026, 10:40 a.m.

Sponsor, product, and application records imported from Animal Drugs @ FDA.

Safety reports
No safety reports linked
No refresh timestamp yet

openFDA reaction terms and case summaries are supporting evidence, not proof of causality.

Source timing details
Source timing details
  • Reference facts: Source Roxee | Refreshed Jun 22, 2026, 10:40 AM UTC
    The reference fact projection used for browse cards and quick facts.
  • Animal Drugs @ FDA: Source FDA | Refreshed Jun 22, 2026, 10:40 AM UTC
    Applications/products are imported from FDA export data.
  • Animal Drugs @ FDA previews: Source FDA | Refreshed Feb 9, 2026, 3:05 AM UTC
    Label highlights/doc links are fetched from FDA preview endpoints.
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Etodolac

Etodolac

Drug type: Generic ingredient • Generic profile • No FDA branded products linked

Both Tablet Rx required 100% reference complete

Species: Both

Manufacturer: Boehringer Ingelheim Animal Health USA Inc.

Medication Snapshot

Merged from the current Roxee medication system with field-level provenance, freshness, and completeness tracking.

Etodolac

EtoGesic Tablets are indicated for the control of pain and inflammation associated with osteoarthritis in dogs. For the control of pain and inflammation associated with osteoarthritis. Species commonly shown: Both, Dog.

Generic name
Etodolac
Brand names
EtoGesic® Tablets, Etogesic® Sterile Injectable Solution
Manufacturer
Boehringer Ingelheim Animal Health USA Inc.
Species
Both, Dog
Dosage forms
Tablet, Liquid (Solution)
Prescription
Prescription required
Completeness
100%
Validation
Complete
Brand names
EtoGesic® Tablets Etogesic® Sterile Injectable Solution
Dosage forms
Tablet Liquid (Solution)

Indications / Uses

EtoGesic Tablets are indicated for the control of pain and inflammation associated with osteoarthritis in dogs. For the control of pain and inflammation associated with osteoarthritis.

Warnings / Contraindications

Do not use in cats. For use in dogs only. Federal law restricts this drug to use by or on the order of a licensed veterinarian Due to tablet sizes and scoring, dogs weighing less than 11 lb (5 kg) cannot be accurately dosed. The initial dose level should be adjusted until a satisfactory clinical response is obtained, but should not exceed 15 mg/kg once daily. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

  • Do not use in cats. For use in dogs only. Federal law restricts this drug to use by or on the order of a licensed veterinarian Due to tablet sizes and scoring, dogs weighing less than 11 lb (5 kg) cannot be accurately dosed. The initial dose level should be adjusted until a satisfactory clinical response is obtained, but should not exceed 15 mg/kg once daily. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Side Effects

Top reported reactions (openFDA): Blood in faeces, Crying, Death by euthanasia, Diarrhoea, Lack of efficacy - NOS, Malaise.

FAQ

Both, Dog

Yes. Roxee shows this as prescription-only.

Tablet, Liquid (Solution)

Related Conditions

Osteoarthritis (Degenerative Joint Disease) Osteoarthritis (Degenerative Joint Disease) Pain (acute, chronic)

Source Transparency

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Pet Owner Quick Guide

Start here first for the safest next-step summary before the deeper medication detail.

Used for:

For the control of pain and inflammation associated with osteoarthritis.

Dosing note:

Exact dosing depends on your pet's species, weight, and health status. Use your veterinarian's instructions for the exact dose and schedule.

What to watch for:

  • Do not use in cats
  • For use in dogs only
  • The initial dose level should be adjusted until a satisfactory clinical response is obtained, but should not exceed 15 mg/kg once daily
  • Vomiting (1 reports)
  • Pain NOS (1 reports)
  • Malaise (1 reports)

When to call the vet:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
  • Facial swelling or hives.
  • Blood in vomit or stool.

Regulatory restrictions are shown in Vet View.

What to tell or ask your vet today:

  • Is this medicine the right fit for my pet’s current symptoms?
  • Which warning signs mean I should call back right away?
  • How should I handle missed doses or refusal to take the medicine?

Next actions

Talk to a Vet / Find a Vet Near You Save to pet meds Share page Review report evidence
Research brief

Medication Research Insights

A source-aware map of what to know, what is uncertain, and what to verify with your veterinarian.

Source Backed Signals

What to know

Evidence-backed context Limited

Roxee has limited cited overview evidence for Etodolac; use the official documents and your veterinarian's instructions for product-specific decisions.

Source: openFDA case USA-USFDACVM-2018-US-010493
Safety signal coverage Reported signals

8 tracked reaction signals; 8 reported cases; 8 serious reports; 1 species group. These are reporting and label-derived signals for interpretation with a veterinarian.

Source: openFDA case USA-USFDACVM-2018-US-010493
Interpretation guardrail Not causation

Adverse-event reports help form a watch list, but they do not prove the medication caused the reaction and they are not a risk ranking between medications.

Evidence tension

Stronger signal Label / review

Official labels, package inserts, and reviewed summaries carry more weight than isolated reports.

Source: openFDA case USA-USFDACVM-2018-US-010493
Weaker signal Reported data

Case reports and openFDA terms are useful for pattern awareness, but they are incomplete, can include multiple exposures, and do not estimate an individual pet's probability of harm.

Reaction signal map

Most reported reactions Top terms

Vomiting (1 reports), Pain NOS (1 reports), Malaise (1 reports), Lack of efficacy - NOS (1 reports), Diarrhea (1 reports)

Body systems represented Signal grouping

Digestive (2), Effectiveness (1), Other (5)

Species and breed lens

Species represented in reports Species lens

Dog (8 reports)

What your vet may verify

Fit for this patient Vet check

Verify whether Etodolac fits the pet's species, current diagnosis, age, weight, organ status, pregnancy/lactation status, and concurrent medications.

Evidence limitations Evidence review

Separate label-backed warnings from adverse-event reports and owner observations before changing the plan.

What to watch next

Watch list Owner-safe

Do not use in cats, For use in dogs only, The initial dose level should be adjusted until a satisfactory clinical response is obtained, but sh, Vomiting, Pain NOS

Call sooner if Escalation

Repeated vomiting or diarrhea. Severe lethargy (hard to wake, very low energy). Collapse or fainting.

Bottom line: Use this Etodolac brief as a structured watch list and source map, not as a reason to start, stop, or change treatment without your veterinarian.
Vet source depth
  1. openFDA case USA-USFDACVM-2018-US-010493 · adverse_reaction · adverse reactions
  2. Contraindication source · fda_animal_drugs · warnings contraindications
  3. FDA application profile · official_label · quick facts
  4. FDA application profile · official_label · quick facts
  5. Medication usage source · fda_animal_drugs · quick facts
  6. FOI · document · documents
  7. Labeling · document · documents
  8. SPL · document · documents

Evidence

Review status / Updated / Sources

Review status: Clinical reviewer not listed

Updated: February 12, 2026, 10:44 PM UTC

Sources:
Safety & side effects

Side effects to monitor:

  • Do not use in cats
  • For use in dogs only
  • The initial dose level should be adjusted until a satisfactory clinical response is obtained, but should not exceed 15 mg/kg once daily
  • Vomiting
  • Pain NOS

Most reported reactions:

  • Vomiting (1 reports)
  • Pain NOS (1 reports)
  • Malaise (1 reports)

Emergency warning signs:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
Talk to a Vet / Find a Vet Near You Start Symptom Intake

Vet Fast Scan

Source-backed clinical checkpoints for quick review.

FDA-labeled species
Dog
Indication / use
For the control of pain and inflammation associated with osteoarthritis.
Form / route / dose
Form: Liquid (Solution), Tablet
Route: Oral, Subcutaneous
Confirm product label and patient-specific plan.
Warnings
  • High: Do not use in cats. For use in dogs only. Federal law restricts this drug to use by or on the order of a licensed veter…
Adverse-event caveat
No stored openFDA case explorer rows are linked yet.
Source docs

Quick Facts

Official label facts first, then secondary summaries. Marketing content is separated below.

Species: Both
Manufacturer: Boehringer Ingelheim Animal Health USA Inc.
Form: Liquid (Solution), Tablet
Identifiers:
NADA: 141108 NADA: 141274
Source metadata:

Warnings / Contraindications

Do not use in cats. For use in dogs only. Federal law restricts this drug to use by or on the order of a licensed veterinarian Due to tablet sizes and scoring, dogs weighing less than 11 lb (5 kg) cannot be accurately dosed. The initial dose level should be adjusted until a satisfactory clinical response is obtained, but should not exceed 15 mg/kg once daily. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

  • High: Do not use in cats. For use in dogs only. Federal law restricts this drug to use by or on the order of a licensed veterinarian Due to tablet sizes and scoring, dogs weighing less than 11 lb (5 kg) cannot be accurately dosed. The initial dose level should be adjusted until a satisfactory clinical response is obtained, but should not exceed 15 mg/kg once daily. Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Source metadata:

Adverse Reactions

Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.

Tap or hover a reaction to see what it means in plain language.

Tracked signals
8
Reported cases
8
Serious reports
8
Species represented
1
Grouped by Body System
Digestive (2) · Vomiting, Diarrhea Effectiveness (1) · Lack of efficacy - NOS Other (5) · Pain NOS, Malaise, Death by euthanasia
Most Reported Reactions
Reaction Body system Cases Species Serious cases
Digestive 1 Dog 1
Other 1 Dog 1
Other 1 Dog 1
Effectiveness 1 Dog 1
Digestive 1 Dog 1
Other 1 Dog 1
Other 1 Dog 1
Other 1 Dog 1

Species coverage: Dog (8)

View detailed reaction table
Reaction Body system Species Seriousness Frequency Reports
Digestive Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Effectiveness Dog Serious - 1
Digestive Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Source metadata:

Source Documents

The most useful source links appear first; full previews and metadata stay in the veterinary/professional layer.

Use original documents to confirm product-specific warnings, ingredients, and handling details with your veterinarian.

UCM305378.pdf Official label / PI · Labeling UCM050388.pdf Official label / PI · Labeling UCM050389.pdf Official label / PI · Labeling

Full source previews and metadata remain in the veterinary/professional layer.

Owner handouts

0
No owner handouts linked yet.

Official label / PI

3

SPL

2

FOI

3

UCM305378.pdf

Official label / PI · Labeling

Open original

UCM050388.pdf

Official label / PI · Labeling

Open original

UCM050389.pdf

Official label / PI · Labeling

Open original

Etogesic® Sterile Injectable Solution

SPL · SPL

Open original
FDA Structured Product Label

Etogesic® Sterile Injectable Solution

Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.

Sponsor
Boehringer Ingelheim Animal Health USA Inc.
NADA
141-274
Status
RX
Form
Liquid (Solution)
Route
Subcutaneous
Species
Dog
Composition / specifications
Each mL of ETOGESIC Injectable contains 100 mg of etodolac

Dogs

Indication
For the control of pain and inflammation associated with osteoarthritis.
Dosage
Administer 4.5 to 6.8 mg/pound (10 to 15 mg/kilogram) body weight as a single, dorsoscapular subcutaneous injection. If needed, the daily dose of etodolac tablets may be given 24 hours after the injection.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian.

EtoGesic® Tablets

SPL · SPL

Open original
FDA Structured Product Label

EtoGesic® Tablets

Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.

Sponsor
Boehringer Ingelheim Animal Health USA Inc.
NADA
141-108
Status
RX
Form
Tablet
Route
Oral
Species
Dog
Composition / specifications
Each tablet is biconvex and half-scored and contains either 150 or 300 mg of etodolac.

Dogs

Indication
EtoGesic Tablets are indicated for the control of pain and inflammation associated with osteoarthritis in dogs.
Dosage
The recommended dose of EtoGesicTabletsis4.5 to6.8mg/lb body weight (10 to 15 mg/kg) administered once daily.
Limitations
Do not use in cats. For use in dogs only. Federal law restricts this drug to use by or on the order of a licensed veterinarian Due to tablet sizes and scoring, dogs weighing less than 11 lb (5 kg) cannot be accurately dosed. The initial dose level should be adjusted until a satisfactory clinical response is obtained, but should not exceed 15 mg/kg once daily.

ucm062330.pdf

FOI · FOI

Open original

ucm117141.pdf

FOI · FOI

Open original

N141108 Orig_7_22_1998.pdf

FOI · FOI

Open original
Source metadata:
Veterinary reference (advanced)

Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.

At a Glance

Quick facts and links to official labeling and safety signals.

Data freshness
  • Reference facts: Source Roxee | Refreshed Jun 22, 2026, 10:40 AM UTC
    The reference fact projection used for browse cards and quick facts.
  • Animal Drugs @ FDA: Source FDA | Refreshed Jun 22, 2026, 10:40 AM UTC
    Applications/products are imported from FDA export data.
  • Animal Drugs @ FDA previews: Source FDA | Refreshed Feb 9, 2026, 3:05 AM UTC
    Label highlights/doc links are fetched from FDA preview endpoints.
Official (FDA)
Identity: Generic ingredient • No FDA branded products linked
No official FDA brand rows linked yet for this ingredient.
Catalog species: Both • FDA-labeled species: Dog
Rx/OTC: RX
Form/route: Liquid (Solution), Tablet • Oral, Subcutaneous
Applications: NADA 141-274 • NADA 141-108
Documents: 6 (FOI: 3) • SPL: 2 • Label highlights • Official documents
Safety (openFDA)
Top reactions: Dog 0 • Cat 0 • View
Case summaries: 0
openFDA reports are unverified and do not prove causation.
Explore
Linked using: Fda_Label (0.95), Fda_Label (0.95), Fda_Label (0.95)
Diagnosis Codes
ICD10_CM: M19.90
Unspecified osteoarthritis, unspecified site

Counseling and Monitoring Highlights

Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.

Owner-facing counseling points
  • Do not use in cats. For use in dogs only. Federal law restricts this drug to use by or on the order of a licensed veterinarian Due to tablet sizes and scoring, dogs weighing less than 11 lb (5 kg) cannot be accurately dosed. The initial dose level should be adjusted until a satisfactory clinical response is obtained, but should not exceed 15 mg/kg once daily. Federal law restricts this drug to use by or on the order of a licensed veterinarian. (Contraindication, High)
Top reaction signals
Vomiting (1) Pain NOS (1) Malaise (1) Lack of efficacy - NOS (1) Diarrhea (1) Death by euthanasia (1) Crying (1) Blood in faeces (1)

Identifiers & Packages

Normalized identifiers (NDC/NADA/ANADA) and package metadata from regulator listings.

Identifiers
NADA: 141108 NADA: 141274

Enriched Documents

Documents are tiered by source trust: Official, Clinical, Manufacturer, Marketing.

  • UCM305378.pdf • Official label • Official • May 15, 2024
    FDA official labeling for application 141274
  • ucm062330.pdf • FOI summary • Official • May 15, 2024
    FDA FOI summary for application 141274
  • UCM050389.pdf • Official label • Official • May 15, 2024
    FDA official labeling for application 141108
  • UCM050388.pdf • Official label • Official • May 15, 2024
    FDA official labeling for application 141108
  • N141108 Orig_7_22_1998.pdf • FOI summary • Official • May 15, 2024
    FDA FOI summary for application 141108
  • ucm117141.pdf • FOI summary • Official • May 15, 2024
    FDA FOI summary for application 141108

Data Sources & Change Log

Every non-trivial field is expected to include provenance and update timestamps.

Official 72 Clinical 1 Manufacturer 0 Marketing 0
Current Field Facts
  • side_effects: Top reported reactions (openFDA): Blood in faeces, Crying, Death by euthanasia, Diarrhoea, Lack of efficacy - NOS, Malaise. (Clinical, 2026-04-11)
  • contraindications: Do not use in cats. For use in dogs only. Federal law restricts this drug to use by or on the order of a licensed veterinarian Due to tablet sizes and scoring,… (Official, 2026-04-11)
  • contraindications: Do not use in cats. For use in dogs only. Federal law restricts this drug to use by or on the order of a licensed veterinarian Due to tablet sizes and scoring,… (Official, 2026-02-12)
  • indications: ETOGESIC Injectable is indicated for the control of pain and inflammation associated with osteoarthritis in dogs. (Official, 2026-06-22)
  • indications: ETOGESIC Injectable is indicated for the control of pain and inflammation associated with osteoarthritis in dogs. (Official, 2026-06-22)
  • indications: ETOGESIC Injectable is indicated for the control of pain and inflammation associated with osteoarthritis in dogs. (Official, 2026-06-21)
  • indications: ETOGESIC Injectable is indicated for the control of pain and inflammation associated with osteoarthritis in dogs. (Official, 2026-06-20)
  • indications: ETOGESIC Injectable is indicated for the control of pain and inflammation associated with osteoarthritis in dogs. (Official, 2026-06-13)
  • indications: ETOGESIC Injectable is indicated for the control of pain and inflammation associated with osteoarthritis in dogs. (Official, 2026-06-12)
  • indications: ETOGESIC Injectable is indicated for the control of pain and inflammation associated with osteoarthritis in dogs. (Official, 2026-06-12)
  • indications: ETOGESIC Injectable is indicated for the control of pain and inflammation associated with osteoarthritis in dogs. (Official, 2026-06-11)
  • indications: ETOGESIC Injectable is indicated for the control of pain and inflammation associated with osteoarthritis in dogs. (Official, 2026-06-11)
  • indications: ETOGESIC Injectable is indicated for the control of pain and inflammation associated with osteoarthritis in dogs. (Official, 2026-06-10)
  • indications: ETOGESIC Injectable is indicated for the control of pain and inflammation associated with osteoarthritis in dogs. (Official, 2026-06-09)
  • indications: ETOGESIC Injectable is indicated for the control of pain and inflammation associated with osteoarthritis in dogs. (Official, 2026-06-08)
  • indications: ETOGESIC Injectable is indicated for the control of pain and inflammation associated with osteoarthritis in dogs. (Official, 2026-06-07)
  • indications: ETOGESIC Injectable is indicated for the control of pain and inflammation associated with osteoarthritis in dogs. (Official, 2026-06-06)
  • indications: ETOGESIC Injectable is indicated for the control of pain and inflammation associated with osteoarthritis in dogs. (Official, 2026-06-05)
  • indications: ETOGESIC Injectable is indicated for the control of pain and inflammation associated with osteoarthritis in dogs. (Official, 2026-06-04)
  • indications: ETOGESIC Injectable is indicated for the control of pain and inflammation associated with osteoarthritis in dogs. (Official, 2026-06-03)
Recent Revisions
  • side_effects updated 2026-04-11 10:05 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-04-11 10:05 by etl_backfill • Backfilled from existing medication fields
  • usage updated 2026-04-11 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields
  • usage updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields

FDA Products & Applications (Animal Drugs @ FDA)

Official sponsor/proprietary-name/application-status records linked by active ingredient.

Product Sponsor Application Status Published
Etogesic® Sterile Injectable Solution
RX
Etodolac
Liquid (Solution) • Subcutaneous
Label highlights
Official documents
Boehringer Ingelheim Animal Health USA Inc. NADA 141-274 W May 15, 2024
EtoGesic® Tablets
RX
Etodolac
Tablet • Oral
Label highlights
Official documents
Boehringer Ingelheim Animal Health USA Inc. NADA 141-108 W May 15, 2024

Data source: FDA Animal Drugs @ FDA (public search export).

What It's For (FDA Label Highlights)

Extracted from FDA Animal Drugs @ FDA product labeling. Always confirm details with your veterinarian.

Species: Dog
Composition / specifications
Each mL of ETOGESIC Injectable contains 100 mg of etodolac
Dogs
Indication
For the control of pain and inflammation associated with osteoarthritis.
Dosage
Administer 4.5 to 6.8 mg/pound (10 to 15 mg/kilogram) body weight as a single, dorsoscapular subcutaneous injection. If needed, the daily dose of etodolac tablets may be given 24 hours after the injection.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian.

FDA page: Open in Animal Drugs @ FDA

Species: Dog
Composition / specifications
Each tablet is biconvex and half-scored and contains either 150 or 300 mg of etodolac.
Dogs
Indication
EtoGesic Tablets are indicated for the control of pain and inflammation associated with osteoarthritis in dogs.
Dosage
The recommended dose of EtoGesicTabletsis4.5 to6.8mg/lb body weight (10 to 15 mg/kg) administered once daily.
Limitations
Do not use in cats. For use in dogs only. Federal law restricts this drug to use by or on the order of a licensed veterinarian Due to tablet sizes and scoring, dogs weighing less than 11 lb (5 kg) cannot be accurately dosed. The initial dose level should be adjusted until a satisfactory clinical response is obtained, but should not exceed 15 mg/kg once daily.

FDA page: Open in Animal Drugs @ FDA

Usage

EtoGesic Tablets are indicated for the control of pain and inflammation associated with osteoarthritis in dogs. For the control of pain and inflammation associated with osteoarthritis.

Source: FDA Animal Drugs @ FDA • Reference

Contraindications

Do not use in cats. For use in dogs only. Federal law restricts this drug to use by or on the order of a licensed veterinarian Due to tablet sizes and scoring, dogs weighing less than 11 lb (5 kg) cannot be accurately dosed. The initial dose level should be adjusted until a satisfactory clinical response is obtained, but should not exceed 15 mg/kg once daily. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Top Reported Reactions (openFDA)

De-duplicated reaction terms grouped by body system from FDA openFDA reports (not verified; does not prove causation).

Digestive
Vomiting (1) • Dog Diarrhea (1) • Dog

Showing top 5 for Digestive.

Effectiveness
Lack of efficacy - NOS (1) • Dog

Showing top 5 for Effectiveness.

Other
Pain NOS (1) • Dog Malaise (1) • Dog Death by euthanasia (1) • Dog Crying (1) • Dog Blood in faeces (1) • Dog

Showing top 5 for Other.

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Adverse Event Case Summaries (openFDA)

These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.

No case-level openFDA reports are linked for this medication yet.

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Overdose Information

No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.

Storage & Handling

No approved storage guidance is linked yet for this ingredient. Use manufacturer packaging and veterinary guidance for handling/storage.

Share Your Thoughts

Let others know your experience or advice regarding this medication.

This medication has not been reviewed by a veterinarian yet.