Roxee Medication Guide

Frunevetmab

Medication reference facts with explicit FDA-approval, off-label, source-limited, and safety context. Roxee does not sell, prescribe, or dispense medications.

Both Reference complete FDA data linked Sources vary Rx required Injection Zoetis Inc. Official label facts Owner quick guide first

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Source variance noted. Roxee found source differences in non-clinical fields such as brand, manufacturer, source URL, or display metadata. Core owner guidance and official source links are still available.

Source variance fields

Dosage forms (Official label describes Solensia as frunevetmab injection.)

Data freshness

Reference facts

Reference refreshed

Aug 6, 2026, 7:58 p.m.

These are the reference facts Roxee uses on browse cards and quick facts.

FDA applications

FDA application data refreshed

Aug 6, 2026, 7:47 p.m.

Sponsor, product, and application records imported from Animal Drugs @ FDA.

Safety reports

Safety data refreshed

Aug 6, 2026, 7:49 p.m.

openFDA reaction terms and case summaries are supporting evidence, not proof of causality.

Source timing details

Reference facts: Source Roxee | Refreshed Aug 6, 2026, 7:58 PM UTC
The reference fact projection used for browse cards and quick facts.
Animal Drugs @ FDA: Source FDA | Refreshed Aug 6, 2026, 7:46 PM UTC
Applications/products are imported from FDA export data.
Animal Drugs @ FDA previews: Source FDA | Refreshed May 15, 2026, 10:00 AM UTC
Label highlights/doc links are fetched from FDA preview endpoints.
Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed Aug 6, 2026, 7:47 PM UTC
Package/product NDCs from FDA’s electronic listing directory (XLS).
openFDA reaction terms: Source FDA openFDA | Refreshed Aug 6, 2026, 7:52 PM UTC
openFDA case summaries: Source FDA openFDA | Refreshed Aug 6, 2026, 7:52 PM UTC

Illustration placeholder

Frunevetmab

Drug type: Generic ingredient • Branded profile • FDA branded products available

Both Injection Rx required 100% reference complete

Species: Both

Manufacturer: Zoetis Inc.

Medication Snapshot

Merged from the current Roxee medication system with field-level provenance, freshness, and completeness tracking.

Frunevetmab

For the control of pain associated with osteoarthritis in cats. Species commonly shown: Cats.

Generic name

Frunevetmab

Brand names

Solensia™, Solensia

Medication class

branded

Manufacturer

Zoetis Inc.

Species

Cat

Dosage forms

Injection

Strengths

7 mg/mL

Prescription

Prescription required

Completeness

100%

Validation

Complete

Brand names

Solensia™ Solensia

Dosage forms

Injection

Strengths

7 mg/mL

Indications / Uses

For the control of pain associated with osteoarthritis in cats.

Administration / How To Give

Administer by subcutaneous injection once a month, dosed by weight range, as directed and given by a veterinarian.

Warnings / Contraindications

Do not administer Solensia to cats with known hypersensitivity to frunevetmab.

Do not administer Solensia to cats with known hypersensitivity to frunevetmab; accidental self-injection can cause hypersensitivity reactions in people.

Side Effects

Top reported reactions (openFDA): General illness, Lethargy (see also Central nervous system depression in Neurological), Prescribing error, Anorexia, Behavioural disorder NOS, Confusion.

FAQ

Cats

Yes. Roxee shows this as prescription-only.

Injection, Injectable Solution

Related Conditions

Osteoarthritis (Degenerative Joint Disease) Osteoarthritis (Degenerative Joint Disease) Pain (acute, chronic)

Source Transparency

Verified source: https://www.roxee.ai/meds/
Verified source: https://animaldrugsatfda.fda.gov
Verified source: https://animaldrugsatfda.fda.gov/adafda/views/#/search
Verified source: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a73b79c4-3623-4b52-81ea-6180528a031e
Verified source: https://api.fda.gov/animalandveterinary/event.json
Verified source: https://www.roxee.ai/conditions/
Last refreshed: Aug 6, 2026, 7:58 p.m.
Last verified: May 15, 2026, 10:04 a.m.
Validation status: Complete

Add to My Pet's Medications

Choose a pet, confirm current or past, and optionally add reminder notes.

Pet Owner Quick Guide

Start here first for the safest next-step summary before the deeper medication detail.

Used for:

For the control of pain associated with osteoarthritis in cats.

Dosing note:

Exact dosing depends on your pet's species, weight, and health status. Use your veterinarian's instructions for the exact dose and schedule.

What to watch for:

wobbly/unsteady walking (1 reports)
Hair loss (1 reports)
Blood clot (1 reports)

When to call the vet:

Repeated vomiting or diarrhea.
Severe lethargy (hard to wake, very low energy).
Collapse or fainting.
Trouble breathing.
Facial swelling or hives.
Blood in vomit or stool.

What to tell or ask your vet today:

Is this medicine the right fit for my pet’s current symptoms?
Which warning signs mean I should call back right away?
How should I handle missed doses or refusal to take the medicine?

Next actions

Talk to a Vet / Find a Vet Near You Save to pet meds Share page Review report evidence

Research brief

Medication Research Insights

A source-aware map of what to know, what is uncertain, and what to verify with your veterinarian.

Source Backed Signals

What to know

Evidence-backed context Limited

Roxee has limited cited overview evidence for Frunevetmab; use the official documents and your veterinarian's instructions for product-specific decisions.

Source: openFDA case USA-USFDACVM-2025-US-069686

Safety signal coverage Reported signals

32 tracked reaction signals; 32 reported cases; 27 serious reports; 2 species groups. These are reporting and label-derived signals for interpretation with a veterinarian.

Source: openFDA case USA-USFDACVM-2025-US-069686

Interpretation guardrail Not causation

Adverse-event reports help form a watch list, but they do not prove the medication caused the reaction and they are not a risk ranking between medications.

Evidence tension

Stronger signal Label / review

Official labels, package inserts, and reviewed summaries carry more weight than isolated reports.

Source: openFDA case USA-USFDACVM-2025-US-069686

Weaker signal Reported data

Case reports and openFDA terms are useful for pattern awareness, but they are incomplete, can include multiple exposures, and do not estimate an individual pet's probability of harm.

Reaction signal map

Most reported reactions Top terms

Unsteady walking (ataxia) (1 reports), Hair loss (1 reports), Blood clot (1 reports), Blindness (1 reports), Bladder distension (1 reports)

Body systems represented Signal grouping

Digestive (1), Skin & allergy (3), Neurologic (1), Behavior (1)

Explore supporting adverse reports

Species and breed lens

Species represented in reports Species lens

Cat (31 reports), Dog (1 reports)

Breed metadata in reports Metadata only

Domestic Shorthair (4), Cat (other) (2), Domestic Mediumhair (2). These are report metadata, not proof that a breed is at higher risk.

What your vet may verify

Fit for this patient Vet check

Verify whether Frunevetmab fits the pet's species, current diagnosis, age, weight, organ status, pregnancy/lactation status, and concurrent medications.

Evidence limitations Evidence review

Separate label-backed warnings from adverse-event reports and owner observations before changing the plan.

What to watch next

Watch list Owner-safe

wobbly/unsteady walking, Hair loss, Blood clot

Call sooner if Escalation

Repeated vomiting or diarrhea. Severe lethargy (hard to wake, very low energy). Collapse or fainting.

Bottom line: Use this Frunevetmab brief as a structured watch list and source map, not as a reason to start, stop, or change treatment without your veterinarian.

Vet source depth

openFDA case USA-USFDACVM-2025-US-069686 · adverse_reaction · adverse reactions
Contraindication and user safety warning from the official Solensia label. · safety_warning · warnings contraindications
FDA application profile · official_label · quick facts
Medication usage source · fda_animal_drugs · quick facts
FOI · document · documents
SPL · document · documents
Safety communication · document · documents
Official label · document · documents

Evidence

Review status / Updated / Sources

Review status: Clinical reviewer not listed

Updated: May 15, 2026, 10:04 AM UTC

Sources:

FDA application profile · official_label
Medication usage source · fda_animal_drugs
Contraindication and user safety warning from the official Solensia label. · safety_warning
openFDA case USA-USFDACVM-2025-US-069686 · adverse_reaction
FOI · document

Safety & side effects

Side effects to monitor:

wobbly/unsteady walking
Hair loss
Blood clot

Most reported reactions:

Unsteady walking (ataxia) (1 reports)
Hair loss (1 reports)
Blood clot (1 reports)

Explore reported case details

Emergency warning signs:

Repeated vomiting or diarrhea.
Severe lethargy (hard to wake, very low energy).
Collapse or fainting.
Trouble breathing.

Talk to a Vet / Find a Vet Near You Start Symptom Intake

Vet Fast Scan

Source-backed clinical checkpoints for quick review.

FDA-labeled species

Cat

Indication / use

For the control of pain associated with osteoarthritis in cats.

Form / route / dose

Form: Injectable Solution
Route: Subcutaneous
Confirm product label and patient-specific plan.

Warnings

No structured warnings linked yet.

Adverse-event caveat

openFDA adverse-event cases are reported signals. They are not verified, do not prove causation, and do not estimate a pet's individual risk.

Source docs

FDA Osteoarthritis in Cats Official label / PI
Solensia Official Label (DailyMed) Official label / PI
Solensia™ SPL

Quick Facts

Official label facts first, then secondary summaries. Marketing content is separated below.

Species: Both

Manufacturer: Zoetis Inc.

Form: Injectable Solution

Identifiers:

NADA: 141546 NDC Package: 54771-3520-1 NDC Package: 54771-3520-2 NDC Product: 54771

Source metadata:

https://animaldrugsatfda.fda.gov/adafda/views/#/home/previewsearch/141546 · official_label · FDA application profile
https://animaldrugsatfda.fda.gov · fda_animal_drugs · Medication usage source

Adverse Reactions

Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.

Reported case explorer

Filter stored openFDA reports by pet and report attributes. Counts describe reports in this data set, not risk.

Clear filters

openFDA adverse-event cases are reported signals. They are not verified, do not prove causation, and do not estimate a pet's individual risk.

Stored reports

Matching reports

Active filters

Species

Breed

Size / weight

Age

Sex

Seriousness

Outcome

Reaction

Body system

Region

Received after

Received before

Reset

Drill into common report signals

Intentional misuse (11) Lethargy (see also Central nervous system depression in Neurological) (11) Abnormal radiograph finding (10) Decreased appetite (10) Other (83) Digestive (26) Neurologic (23) Skin & allergy (19)

Showing up to 50 matching reports. Narrow filters to inspect the remaining reports.

USA-USFDACVM-2026-US-014454

Received 2026-03-26 · MSK · MSK

Non-serious

Species: Cat
Breed: Domestic Shorthair
Size / weight: Under 10 lb (3.992 Kilogram)
Age: 8+ years (11 Year)
Sex: Female Unknown
Region: USA
Reactions: Facial pruritusMedication error NOS
Body systems: Skin & allergyOther
Outcomes: Recovered/Normal

USA-USFDACVM-2026-US-014418

Received 2026-03-26 · MSK · MSK

Serious

Species: Cat
Breed: Cat (other)
Age: 8+ years (17 Year)
Sex: Female Unknown
Region: USA
Reactions: Acute renal failureListless
Body systems: Other
Outcomes: Recovered/Normal

USA-USFDACVM-2026-US-014416

Received 2026-03-26 · MSK · MSK

Serious

Species: Cat
Breed: Cat (other)
Size / weight: 10-24 lb (8.278 Kilogram)
Age: 8+ years (12.5 Year)
Sex: Male Neutered
Region: USA
Reactions: WeaknessAtaxiaGait abnormalityLuxation/subluxationJoint painAbnormal breathingSpondylosis
Body systems: OtherNeurologic
Outcomes: Ongoing

USA-USFDACVM-2026-US-014414

Received 2026-03-26 · MSK · MSK

Non-serious

Species: Cat
Breed: Domestic Shorthair
Age: 4-7 years (4 Year)
Sex: Female Unknown
Region: USA
Reactions: Constipation
Body systems: Other
Outcomes: Ongoing

USA-USFDACVM-2026-US-014412

Received 2026-03-26 · MSK · MSK

Serious

Species: Cat
Breed: Domestic Mediumhair
Size / weight: 10-24 lb (5.053 Kilogram)
Age: 8+ years (19 Year)
Sex: Female Unknown
Region: USA
Reactions: Hind limb paralysisMusculoskeletal disorder NOSUrinary incontinenceProprioception loss
Body systems: Other
Outcomes: Ongoing

USA-USFDACVM-2026-US-014388

Received 2026-03-26 · MSK · MSK

Serious

Species: Cat
Breed: Domestic Mediumhair
Size / weight: 10-24 lb (5.897 Kilogram)
Age: 8+ years (13 Year)
Sex: Male Neutered
Region: USA
Reactions: Skin scab
Body systems: Other
Outcomes: Recovered/Normal

USA-USFDACVM-2026-US-014453

Received 2026-03-25 · MSK · MSK

Non-serious

Species: Cat
Breed: Domestic Shorthair
Size / weight: 10-24 lb (6.895 Kilogram)
Age: 8+ years (14 Year)
Sex: Female Unknown
Region: USA
Reactions: LickingLocalised hair lossSkin scabElevated creatine-kinase (CK)Medication error NOS
Body systems: OtherSkin & allergy
Outcomes: Ongoing

USA-USFDACVM-2026-US-014011

Received 2026-03-25 · MSK · MSK

Serious

Species: Cat
Breed: Domestic Shorthair
Size / weight: Under 10 lb (2.631 Kilogram)
Age: 8+ years (2 Year)
Sex: Female Unknown
Region: USA
Reactions: AgitationVocalisationAtaxiaWeakness
Body systems: OtherNeurologic
Outcomes: Recovered/Normal

USA-USFDACVM-2026-US-013996

Received 2026-03-24 · MSK · MSK

Non-serious

Species: Cat
Breed: Domestic Shorthair
Size / weight: Under 10 lb (3.3 Kilogram)
Age: 8+ years (18 Year)
Sex: Female Unknown
Region: USA
Reactions: Gait abnormalityWalking difficultyDecreased appetite
Body systems: OtherDigestive
Outcomes: Ongoing

USA-USFDACVM-2026-US-013735

Received 2026-03-24 · MSK · MSK

Serious

Species: Cat
Breed: Domestic Mediumhair
Size / weight: Under 10 lb (3.266 Kilogram)
Age: 8+ years (13 Year)
Sex: Female Unknown
Region: USA
Reactions: ConstipationUnable to standHypothermiaTachycardiaTachypnoeaWeight lossDecreased appetiteLateral recumbency
Body systems: OtherDigestive
Outcomes: Ongoing

USA-USFDACVM-2026-US-013469

Received 2026-03-23 · MSK · MSK

Serious

Species: Cat
Breed: Domestic Longhair
Size / weight: Under 10 lb (3.747 Kilogram)
Age: 8+ years (14 Year)
Sex: Female Unknown
Region: USA
Reactions: InappetenceWeight lossElevated symmetrical dimethylarginine (SDMA)Elevated renal parametersHyperphosphataemiaElevated pancreatic enzymesConstipationRenal failureDeath by euthanasiaLethargy (see also Central nervous system depression in Neurological)Other abnormal test result NOSUrinary tract infection
Body systems: OtherNeurologic
Outcomes: Euthanized

USA-USFDACVM-2026-US-013464

Received 2026-03-23 · MSK · MSK

Serious

Species: Cat
Breed: Domestic Shorthair
Size / weight: 10-24 lb (6.169 Kilogram)
Age: 8+ years (16 Year)
Sex: Female Unknown
Region: USA
Reactions: Injection site mass NOSAbnormal radiograph findingFibrosarcoma
Body systems: Other
Outcomes: Ongoing

USA-USFDACVM-2026-US-013327

Received 2026-03-20 · MSK · MSK

Non-serious

Species: Cat
Breed: Domestic Shorthair
Size / weight: 10-24 lb (5.3 Kilogram)
Age: 8+ years (1 Year)
Sex: Female Neutered
Region: USA
Reactions: Elevated betahydroxybutyrate (BHBA)
Body systems: Other
Outcomes: Ongoing

USA-USFDACVM-2026-US-013199

Received 2026-03-19 · MSK · MSK

Serious

Species: Cat
Breed: Domestic Shorthair
Size / weight: 10-24 lb (7.847 Kilogram)
Age: 8+ years (13 Year)
Sex: Male Neutered
Region: USA
Reactions: Musculoskeletal disorder NOSHyperextensionAbnormal radiograph findingElevated alanine aminotransferase (ALT)
Body systems: Other
Outcomes: Ongoing

USA-USFDACVM-2026-US-012950

Received 2026-03-19 · MSK · MSK

Non-serious

Species: Cat
Breed: Domestic Shorthair
Size / weight: Under 10 lb (3.148 Kilogram)
Age: 8+ years (17 Year)
Sex: Male Neutered
Region: USA
Reactions: Immediate pain upon injectionMedication error NOS
Body systems: Other
Outcomes: Recovered/Normal

USA-USFDACVM-2026-US-012931

Received 2026-03-18 · MSK · MSK

Non-serious

Species: Cat
Breed: Tonkinese
Size / weight: 10-24 lb (5.6 Kilogram)
Age: 8+ years (16 Year)
Sex: Male Neutered
Region: USA
Reactions: PolyuriaPolydipsia
Body systems: Other
Outcomes: Ongoing

USA-USFDACVM-2026-US-012692

Received 2026-03-17 · MSK · MSK

Serious

Species: Cat
Breed: Domestic Shorthair
Size / weight: 10-24 lb (5.534 Kilogram)
Age: 8+ years (11 Year)
Sex: Female Unknown
Region: USA
Reactions: VocalisationAgonal breathingDeath
Body systems: Other
Outcomes: Died

USA-USFDACVM-2026-US-013537

Received 2026-03-16 · MSK · MSK

Serious

Species: Cat
Breed: Domestic Longhair
Size / weight: Under 10 lb (4.47 Kilogram)
Age: 4-7 years (7 Year)
Sex: Female Neutered
Region: USA
Reactions: Localised hair lossReddening of the skinItchy skinWoundDermal thickeningAbnormal cytologyIntentional misuseLocal swelling (not application site)Reverse sneezingLeukocytosis NOSThrombocytopeniaNeutrophiliaMonocytosisSkin lesion NOS
Body systems: Skin & allergyOther
Outcomes: Ongoing

USA-USFDACVM-2026-US-013313

Received 2026-03-16 · MSK · MSK

Serious

Species: Cat
Breed: Domestic Shorthair
Size / weight: 10-24 lb (6.427 Kilogram)
Age: 8+ years (13 Year)
Sex: Female Neutered
Region: USA
Reactions: PruritusSkin lesion NOSSkin scab
Body systems: Skin & allergyOther
Outcomes: Ongoing

USA-USFDACVM-2026-US-012631

Received 2026-03-16 · MSK · MSK

Serious

Species: Cat
Breed: Domestic Longhair
Size / weight: Under 10 lb (3.81 Kilogram)
Age: 8+ years (13 Year)
Sex: Female Unknown
Region: USA
Reactions: Emesis (multiple)VocalisationJoint ligament disorder NOS
Body systems: DigestiveOther
Outcomes: Ongoing

USA-USFDACVM-2026-US-012583

Received 2026-03-16 · MSK · MSK

Serious

Species: Cat
Breed: American Shorthair
Size / weight: Under 10 lb (3.311 Kilogram)
Sex: Female Unknown
Region: USA
Reactions: Decreased appetiteBehavioural disorder NOSPulmonary oedemaDyspnoeaIntentional misuse
Body systems: DigestiveBehaviorOther
Outcomes: Recovered/Normal

USA-USFDACVM-2026-US-011901

Received 2026-03-11 · MSK · MSK

Non-serious

Species: Cat
Breed: Domestic Shorthair
Size / weight: 10-24 lb (9.253 Kilogram)
Age: 8+ years (12 Year)
Sex: Male Neutered
Region: USA
Reactions: Peripheral neuropathyPlantigrade posture
Body systems: Other
Outcomes: Ongoing

USA-USFDACVM-2026-US-011867

Received 2026-03-11 · MSK · MSK

Non-serious

Species: Cat
Breed: Domestic Shorthair
Size / weight: Under 10 lb (3.992 Kilogram)
Age: 8+ years (16 Year)
Sex: Female Unknown
Region: USA
Reactions: Tendon rupture
Body systems: Other
Outcomes: Ongoing

USA-USFDACVM-2026-US-011296

Received 2026-03-11 · MSK · MSK

Serious

Species: Cat
Breed: Domestic Mediumhair
Size / weight: Under 10 lb (3.629 Kilogram)
Age: 8+ years (12 Year)
Sex: Female Unknown
Region: USA
Reactions: Tendon rupturePancreas disorderDeath
Body systems: Other
Outcomes: Died

USA-USFDACVM-2026-US-012693

Received 2026-03-08 · MSK · MSK

Serious

Species: Cat
Breed: Domestic Shorthair
Size / weight: Under 10 lb (3.38 Kilogram)
Age: 8+ years (18.5 Year)
Sex: Female Unknown
Region: USA
Reactions: Anaemia NOSThrombocytopeniaIncreased percentage reticulocytes
Body systems: Other
Outcomes: Ongoing

USA-USFDACVM-2026-US-011513

Received 2026-03-06 · MSK · MSK

Serious

Species: Cat
Breed: Domestic Shorthair
Size / weight: 10-24 lb (8.845 Kilogram)
Age: 8+ years (13 Year)
Sex: Male Neutered
Region: USA
Reactions: Injection site abscessInjection site lump
Body systems: Other
Outcomes: Ongoing

USA-USFDACVM-2026-US-010442

Received 2026-03-04 · MSK · MSK

Serious

Species: Cat
Breed: Domestic Shorthair
Size / weight: 10-24 lb (5.806 Kilogram)
Age: 8+ years (17 Year)
Sex: Male Neutered
Region: USA
Reactions: Anaemia NOSHypercalcaemiaElevated symmetrical dimethylarginine (SDMA)Seizure NOSLack of efficacy - NOSIntentional misuse
Body systems: OtherNeurologicEffectiveness
Outcomes: Outcome Unknown

USA-USFDACVM-2026-US-010128

Received 2026-03-04 · MSK · MSK

Non-serious

Species: Cat
Breed: Domestic Shorthair
Size / weight: Under 10 lb (4.354 Kilogram)
Age: 8+ years (15 Year)
Sex: Female Unknown
Region: USA
Reactions: Walking difficultyMusculoskeletal disorder NOSAbnormal posture NOSLimb weaknessAccidental exposure
Body systems: Other
Outcomes: Ongoing

USA-USFDACVM-2026-US-010180

Received 2026-03-02 · MSK · MSK

Serious

Species: Cat
Breed: Domestic Shorthair
Size / weight: 10-24 lb (5.67 Kilogram)
Age: 8+ years (18 Year)
Sex: Male Neutered
Region: USA
Reactions: Seizure NOSAtaxia
Body systems: Neurologic
Outcomes: Ongoing

USA-USFDACVM-2026-US-009997

Received 2026-03-02 · MSK · MSK

Non-serious

Species: Cat
Breed: Domestic Shorthair
Size / weight: 10-24 lb (5.5 Kilogram)
Age: 4-7 years (5 Year)
Sex: Female Unknown
Region: USA
Reactions: Immediate pain upon injectionVocalisationMedication error NOS
Body systems: Other
Outcomes: Ongoing

USA-USFDACVM-2026-US-008769

Received 2026-02-28 · MSK · MSK

Serious

Species: Cat
Breed: Russian
Size / weight: Under 10 lb (4.3 Kilogram)
Age: 8+ years (19 Year)
Sex: Male Neutered
Region: USA
Reactions: Not drinkingNot eatingDullnessAnaemia NOSCardiac disorder NOSHeart murmurPale mucous membraneAtaxiaOliguriaRenal failureDeath by euthanasiaInappetenceLethargy (see also Central nervous system depression in Neurological)AscitesThird eyelid protrusionLateral recumbencyAcute renal failureDehydrationProlonged capillary refill timeHyperglycaemiaSplenic neoplasm NOSHead bobbingElevated blood urea nitrogen (BUN)Elevated creatinineAbnormal radiograph findingAzotaemiaDecreased packed cell volume (PCV)DullHypernatraemia
Body systems: OtherNeurologic
Outcomes: Euthanized

USA-USFDACVM-2026-US-008857

Received 2026-02-27 · MSK · MSK

Serious

Species: Cat
Breed: Domestic Shorthair
Size / weight: Under 10 lb (4.082 Kilogram)
Age: 8+ years (17 Year)
Sex: Female Unknown
Region: USA
Reactions: Hind limb paralysisDeathUnable to walkInjection site reaction NOS
Body systems: Other
Outcomes: Died

USA-USFDACVM-2026-US-008713

Received 2026-02-27 · MSK · MSK

Serious

Species: Cat
Breed: Domestic Shorthair
Size / weight: 10-24 lb (5.806 Kilogram)
Age: 8+ years (12 Year)
Sex: Male Neutered
Region: USA
Reactions: WoundPruritusMedication error NOSLack of efficacy - NOSAlopecia localMoist dermatitisEar infection NOSSkin ulcerHead shake - ear disorderItchy earsAbnormal cytologyEar painEar dischargeLocal erythemaDecreased appetiteExudative skin conditionDiscomfort NOS
Body systems: OtherSkin & allergyEffectivenessDigestive
Outcomes: Ongoing

USA-USFDACVM-2026-US-008852

Received 2026-02-26 · MSK · MSK

Serious

Species: Cat
Breed: Domestic Shorthair
Size / weight: 10-24 lb (4.672 Kilogram)
Age: 8+ years (16.4 Year)
Sex: Female Unknown
Region: USA
Reactions: Diarrhoea
Body systems: Digestive
Outcomes: Ongoing

USA-USFDACVM-2026-US-008733

Received 2026-02-25 · MSK · MSK

Serious

Species: Cat
Breed: Domestic Shorthair
Size / weight: 10-24 lb (6.622 Kilogram)
Age: 8+ years (15 Year)
Sex: Female Unknown
Region: USA
Reactions: Death by euthanasiaOpen mouth breathingDehydrationEnophthalmos (see also Sunken eyes in Systemic disorders)HypersalivationWeak pulseCrackles on auscultationLateral recumbencyPale mucous membraneDepressionAnaphylaxisDecreased haematocritLeukocytosis NOSMonocytosisBasophiliaThrombocytosisHyperglycaemiaElevated creatinineElevated symmetrical dimethylarginine (SDMA)HypocalcaemiaHypokalaemiaProlonged bleeding NOSAbnormal radiograph finding
Body systems: OtherDigestiveNeurologic
Outcomes: Euthanized

USA-USFDACVM-2026-US-010698

Received 2026-02-24 · MSK · MSK

Non-serious

Species: Cat
Breed: Domestic Shorthair
Size / weight: 10-24 lb (6.427 Kilogram)
Age: 8+ years (13 Year)
Sex: Female Neutered
Region: USA
Reactions: PruritusSkin lesion NOSSkin scabLabeled drug-species interactionIntentional misuse
Body systems: Skin & allergyOther
Outcomes: Ongoing

USA-USFDACVM-2026-US-008843

Received 2026-02-24 · MSK · MSK

Serious

Species: Cat
Breed: Domestic Shorthair
Size / weight: Under 10 lb (4.137 Kilogram)
Age: 8+ years (14 Year)
Sex: Female Unknown
Region: USA
Reactions: Plantigrade postureLamenessAbnormal radiograph finding
Body systems: Other
Outcomes: Ongoing

USA-USFDACVM-2026-US-008231

Received 2026-02-24 · MSK · MSK

Serious

Species: Cat
Breed: Domestic Mediumhair
Size / weight: 10-24 lb (5.761 Kilogram)
Age: 8+ years (18 Year)
Sex: Male Neutered
Region: USA
Reactions: Impaired visionBehavioural disorder NOSGait abnormalityBlindnessAbnormal menace reflex testRetinal detachmentRetinal haemorrhageSeizure NOSHigh blood pressureHeart murmurStroke
Body systems: OtherBehaviorNeurologic
Outcomes: Ongoing

USA-USFDACVM-2026-US-009224

Received 2026-02-23 · MSK · MSK

Serious

Species: Cat
Breed: Domestic Shorthair
Size / weight: 10-24 lb (5.443 Kilogram)
Age: 8+ years (14 Year)
Sex: Male Neutered
Region: USA
Reactions: Seizure NOSAtaxia
Body systems: Neurologic
Outcomes: Ongoing

USA-USFDACVM-2026-US-007776

Received 2026-02-20 · MSK · MSK

Serious

Species: Cat
Breed: Maine Coon
Size / weight: Under 10 lb (4.4 Kilogram)
Age: 8+ years (19 Year)
Sex: Female Unknown
Region: USA
Reactions: Elevated globulinsHyperglycaemiaLeukocytosis NOSLethargy (see also Central nervous system depression in Neurological)SneezingNasal dischargePyrexiaNeuropathy NOSEpistaxisHypocalcaemiaUnable to walkMedication error NOSDeath
Body systems: OtherNeurologic
Outcomes: Died

USA-USFDACVM-2026-US-006053

Received 2026-02-13 · MSK · MSK

Serious

Species: Cat
Breed: Domestic Shorthair
Size / weight: 10-24 lb (5.244 Kilogram)
Age: 8+ years (14 Year)
Sex: Female Unknown
Region: USA
Reactions: Hind limb ataxiaWeaknessHind limb paresisUrinary incontinenceLack of efficacy - NOSProprioception lossAbnormal radiograph finding
Body systems: NeurologicOtherEffectiveness
Outcomes: Ongoing

USA-USFDACVM-2026-US-005606

Received 2026-02-05 · MSK · MSK

Non-serious

Species: Cat
Breed: Domestic Shorthair
Size / weight: 10-24 lb (4.64 Kilogram)
Age: 8+ years (21 Year)
Sex: Male Neutered
Region: USA
Reactions: AnisocoriaVomitingNot drinkingElevated symmetrical dimethylarginine (SDMA)Elevated thyroxine (T4)Elevated blood urea nitrogen (BUN)Not eatingElevated alanine aminotransferase (ALT)Elevated creatinine
Body systems: OtherDigestive
Outcomes: Ongoing

USA-USFDACVM-2026-US-006237

Received 2026-02-04 · MSK · MSK

Serious

Species: Cat
Breed: Domestic Shorthair
Size / weight: 10-24 lb (5.987 Kilogram)
Age: 8+ years (13 Year)
Sex: Female Unknown
Region: USA
Reactions: ScratchingNasal congestionSneezingSkin scabSkin inflammation NOSHidingAnorexiaElevated symmetrical dimethylarginine (SDMA)Elevated globulinsProteinuriaThrombocytosisDehydrationLack of efficacy - NOSMedication error NOS
Body systems: OtherDigestiveEffectiveness
Outcomes: Ongoing

USA-USFDACVM-2026-US-003352

Received 2026-01-27 · MSK · MSK

Serious

Species: Cat
Breed: Domestic Shorthair
Size / weight: Under 10 lb (3.992 Kilogram)
Age: 8+ years (13 Year)
Sex: Female Neutered
Region: USA
Reactions: DiarrhoeaDecreased appetiteLethargy (see also Central nervous system depression in Neurological)Bloody diarrhoeaDry mucous membraneOpen mouth breathingUnresponsive to stimuliDecreased haematocritIncreased percentage reticulocytesRegenerative anaemiaIntentional misuseThrombocytopeniaHypersalivationHeart murmur
Body systems: DigestiveNeurologicOther
Outcomes: Ongoing

USA-USFDACVM-2026-US-003803

Received 2026-01-26 · MSK · MSK

Serious

Species: Cat
Breed: Domestic Shorthair
Size / weight: 10-24 lb (4.581 Kilogram)
Age: 8+ years (12 Year)
Sex: Female Neutered
Region: USA
Reactions: Swollen jointMusculoskeletal disorder NOSHyperextensionAbnormal radiograph findingMuscle atrophy (see also Muscle wasting)Decreased blood urea nitrogen (BUN) or creatinine
Body systems: Other
Outcomes: Ongoing

USA-USFDACVM-2026-US-002967

Received 2026-01-20 · MSK · MSK

Non-serious

Species: Cat
Breed: Domestic Shorthair
Size / weight: 10-24 lb (7.031 Kilogram)
Age: 8+ years (13 Year)
Sex: Female Unknown
Region: USA
Reactions: Hair loss NOSFlaking skin
Body systems: Skin & allergyOther
Outcomes: Ongoing

USA-USFDACVM-2026-US-003528

Received 2026-01-19 · MSK · MSK

Serious

Species: Cat
Breed: Domestic Shorthair
Size / weight: Under 10 lb (4 Kilogram)
Age: 8+ years (13 Year)
Sex: Female Neutered
Region: USA
Reactions: Unresponsive to stimuliOpen mouth breathingAnorexiaLethargy (see also Central nervous system depression in Neurological)DiarrhoeaDry mucous membraneBloody diarrhoeaIncreased percentage reticulocytesDecreased haematocritRegenerative anaemiaThrombocytopeniaHypersalivationMurmur
Body systems: OtherDigestiveNeurologic
Outcomes: Ongoing

USA-USFDACVM-2026-US-002536

Received 2026-01-19 · MSK · MSK

Non-serious

Species: Cat
Breed: Bengal
Size / weight: 10-24 lb (5.171 Kilogram)
Age: 8+ years (17 Year)
Sex: Male Neutered
Region: USA
Reactions: Partial lack of efficacy
Body systems: Effectiveness
Outcomes: Ongoing

USA-USFDACVM-2026-US-001275

Received 2026-01-19 · MSK · MSK

Serious

Species: Cat
Breed: Scottish Fold Longhair
Size / weight: Under 10 lb (3.13 Kilogram)
Age: 8+ years (15 Year)
Sex: Female Unknown
Region: USA
Reactions: Decreased appetiteDiarrhoeaVomiting
Body systems: Digestive
Outcomes: Ongoing

USA-USFDACVM-2026-US-002679

Received 2026-01-16 · MSK · MSK

Non-serious

Species: Cat
Breed: Domestic Shorthair
Size / weight: 10-24 lb (4.7 Kilogram)
Age: 8+ years (1 Year)
Sex: Male Neutered
Region: USA
Reactions: Joint ligament disorder NOSLimb weakness
Body systems: Other
Outcomes: Ongoing

Tap or hover a reaction to see what it means in plain language.

Tracked signals

Reported cases

Serious reports

Species represented

Grouped by Body System

Digestive (1) · Loss of appetite Skin & allergy (3) · Hair loss, Alopecia NOS, Alopecia local Neurologic (1) · Unsteady walking (ataxia) Behavior (1) · Behavioral disorder (unspecified) Other (26) · Blood clot, Blindness, Bladder distension

Most Reported Reactions

Body system	Cases	Species	Serious cases
Neurologic	1	Cat	1
Skin & allergy	1	Cat	1
Other	1	Cat	1
Other	1	Cat	1
Other	1	Cat	1
Behavior	1	Cat	1
Other	1	Cat	1
Other	1	Cat	1

Species coverage: Cat (31) Dog (1)

View detailed reaction table

Body system	Species	Seriousness	Frequency	Reports
Neurologic	Cat	Serious	-	1
Digestive	Dog	Non-serious	-	1
Skin & allergy	Cat	Serious	-	1
Other	Cat	Serious	-	1
Other	Cat	Serious	-	1
Other	Cat	Serious	-	1
Behavior	Cat	Serious	-	1
Other	Cat	Serious	-	1
Other	Cat	Non-serious	-	1
Other	Cat	Serious	-	1
Other	Cat	Serious	-	1
Other	Cat	Serious	-	1
Other	Cat	Serious	-	1
Other	Cat	Non-serious	-	1
Other	Cat	Serious	-	1
Other	Cat	Serious	-	1
Skin & allergy	Cat	Serious	-	1
Skin & allergy	Cat	Serious	-	1
Other	Cat	Serious	-	1
Other	Cat	Serious	-	1
Other	Cat	Serious	-	1
Other	Cat	Non-serious	-	1
Other	Cat	Serious	-	1
Other	Cat	Serious	-	1
Other	Cat	Serious	-	1
Other	Cat	Non-serious	-	1
Other	Cat	Serious	-	1
Other	Cat	Serious	-	1
Other	Cat	Serious	-	1
Other	Cat	Serious	-	1
Other	Cat	Serious	-	1
Other	Cat	Serious	-	1

Source metadata:

https://api.fda.gov/animalandveterinary/event.json · adverse_reaction · openFDA case USA-USFDACVM-2025-US-069686

Source Documents

The most useful source links appear first; full previews and metadata stay in the veterinary/professional layer.

Use original documents to confirm product-specific warnings, ingredients, and handling details with your veterinarian.

FDA Osteoarthritis in Cats Official label / PI · Safety communication Solensia Official Label (DailyMed) Official label / PI · Official label Solensia™ SPL · SPL

Full source previews and metadata remain in the veterinary/professional layer.

Owner handouts

No owner handouts linked yet.

Official label / PI

SPL

FOI

FDA Osteoarthritis in Cats

Official label / PI · Safety communication

Open original

This source does not expose a safe inline preview. Use the original source link for the full document.

FDA owner-facing context for osteoarthritis and Solensia in cats.

Solensia Official Label (DailyMed)

Official label / PI · Official label

Open original

This source does not expose a safe inline preview. Use the original source link for the full document.

Official Solensia label.

Solensia™

SPL · SPL

Open original

FDA Structured Product Label

Solensia™

Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.

Sponsor: Zoetis Inc.
NADA: 141-546
Status: RX
Form: Injectable Solution
Route: Subcutaneous
Species: Cat

Composition / specifications

7 mg/mL

Label highlights

Indication

For the control of pain associated with osteoarthritis in cats.

Dosage

The full content of 1 or 2 vials based on body weight to target a minimum dosage of 0.45 mg/lb. (1 mg/kg) body weight, administered subcutaneously once a month.

Solensia SPL

SPL · Structured Product Label

Open original

FDA Structured Product Label XML for Solensia. Use the source link for the full official labeling record.

Solensia SPL

SPL · Structured Product Label

Open original

FDA Structured Product Label XML for Solensia. Use the source link for the full official labeling record.

FOI Summary oN 141-546 Approved January 13, 2022.pdf

FOI · FOI

Open original

Source metadata:

https://animaldrugsatfda.fda.gov/adafda/app/search/public/document/downloadFoi/11817 · document · FOI
https://animaldrugsatfda.fda.gov/adafda/app/search/public/spl/file/11898/Solensia%E2%84%A2 · document · SPL
https://www.fda.gov/animal-veterinary/animal-health-literacy/osteoarthritis-cats-more-common-you-think · document · Safety communication
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a73b79c4-3623-4b52-81ea-6180528a031e · document · Official label
https://www.accessdata.fda.gov/spl/data/41f60cfa-2dbc-4a75-9dff-5c29f74435cd/41f60cfa-2dbc-4a75-9dff-5c29f74435cd.xml · document · Structured Product Label
https://www.accessdata.fda.gov/spl/data/43f946bb-0d3a-42c3-8e2d-689d829a5204/43f946bb-0d3a-42c3-8e2d-689d829a5204.xml · document · Structured Product Label

Veterinary reference (advanced)

Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.

At a Glance

Quick facts and links to official labeling and safety signals.

Data freshness

Reference facts: Source Roxee | Refreshed Aug 6, 2026, 7:58 PM UTC
The reference fact projection used for browse cards and quick facts.
Animal Drugs @ FDA: Source FDA | Refreshed Aug 6, 2026, 7:46 PM UTC
Applications/products are imported from FDA export data.
Animal Drugs @ FDA previews: Source FDA | Refreshed May 15, 2026, 10:00 AM UTC
Label highlights/doc links are fetched from FDA preview endpoints.
Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed Aug 6, 2026, 7:47 PM UTC
Package/product NDCs from FDA’s electronic listing directory (XLS).
openFDA reaction terms: Source FDA openFDA | Refreshed Aug 6, 2026, 7:52 PM UTC
openFDA case summaries: Source FDA openFDA | Refreshed Aug 6, 2026, 7:52 PM UTC

Official (FDA)

Identity: Generic ingredient • FDA branded products available

Official FDA brands: Solensia

Manufacturer mapping: Zoetis Inc.

Case-reported brands (openFDA): MSK

Catalog species: Both • FDA-labeled species: Cat

Rx/OTC: RX

Form/route: Injectable Solution • Subcutaneous

Applications: NADA 141-546

NDC: Packages 54771-3520-1 54771-3520-2 • Products 54771

Documents: 1 (FOI: 1) • SPL: 1 • Label highlights • Official documents

Safety (openFDA)

Top reactions: Dog 3 • Cat 281 • View

Case summaries: 90 (showing 8) • View

openFDA reports are unverified and do not prove causation.

Explore

Related conditions: Osteoarthritis (Degenerative Joint Disease) Osteoarthritis (Degenerative Joint Disease) Pain (acute, chronic)

Linked using: Fda_Label (0.95), Fda_Label (0.95), Fda_Label (0.95)

Diagnosis Codes

ICD10_CM: M19.90

Unspecified osteoarthritis, unspecified site

Counseling and Monitoring Highlights

Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.

Top reaction signals

Unsteady walking (ataxia) (1) Hair loss (1) Blood clot (1) Blindness (1) Bladder distension (1) Behavioral disorder (unspecified) (1) Basophilia (1) Azotaemia (1)

Identifiers & Packages

Normalized identifiers (NDC/NADA/ANADA) and package metadata from regulator listings.

Identifiers

NADA: 141546 NDC Package: 54771-3520-1 NDC Package: 54771-3520-2 NDC Product: 54771

Package NDC	Product NDC	Form / Route	Status
54771-3520-1	54771		-
54771-3520-2	54771		-

Enriched Documents

Documents are tiered by source trust: Official, Clinical, Manufacturer, Marketing.

FDA Osteoarthritis in Cats • Safety communication • Official
FDA owner-facing context for osteoarthritis and Solensia in cats.
Solensia Official Label (DailyMed) • Official label • Official
Official Solensia label.
Solensia SPL • Structured Product Label • Official
FDA Structured Product Label from the electronic animal drug product listing directory.
Solensia SPL • Structured Product Label • Official
FDA Structured Product Label from the electronic animal drug product listing directory.
FOI Summary oN 141-546 Approved January 13, 2022.pdf • FOI summary • Official • May 14, 2026
FDA FOI summary for application 141546

Data Sources & Change Log

Every non-trivial field is expected to include provenance and update timestamps.

Official 117 Clinical 8 Manufacturer 0 Marketing 0

Current Field Facts

monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-21)
monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-20)
monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-19)
monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-17)
monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-16)
monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-16)
monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-15)
side_effects: Top reported reactions (openFDA): General illness, Lethargy (see also Central nervous system depression in Neurological), Prescribing error, Anorexia, Behaviou… (Clinical, 2026-04-11)
administration: Administer by subcutaneous injection once a month, dosed by weight range, as directed and given by a veterinarian. (Official, 2026-04-22)
approval_reference: NADA 141-546 (Official, 2026-04-22)
brand_names: Solensia (Official, 2026-04-22)
contraindications: Do not administer Solensia to cats with known hypersensitivity to frunevetmab. (Official, 2026-04-22)
dosage_forms: Injection (Official, 2026-04-22)
drug_profile_type: branded (Official, 2026-04-22)
indications: For the control of pain associated with osteoarthritis in cats. (Official, 2026-08-06)
indications: For the control of pain associated with osteoarthritis in cats. (Official, 2026-08-05)
indications: For the control of pain associated with osteoarthritis in cats. (Official, 2026-08-04)
indications: For the control of pain associated with osteoarthritis in cats. (Official, 2026-08-03)
indications: For the control of pain associated with osteoarthritis in cats. (Official, 2026-08-02)
indications: For the control of pain associated with osteoarthritis in cats. (Official, 2026-08-01)

Recent Revisions

monitoring updated 2026-08-06 19:58 by curated_loader • Monitoring summary based on official label adverse-reaction and administration sections.
contraindications updated 2026-08-06 19:58 by curated_loader • Official contraindication from the Solensia label.
prescription_required updated 2026-08-06 19:58 by curated_loader • Federal law restricts Solensia to use by or on the order of a licensed veterinarian.
administration updated 2026-08-06 19:58 by curated_loader • Official dosage and administration directions from the Solensia label.
strengths updated 2026-08-06 19:58 by curated_loader • Official label lists Solensia as 7 mg/mL frunevetmab injection.
dosage_forms updated 2026-08-06 19:58 by curated_loader • Official label describes Solensia as frunevetmab injection.
species updated 2026-08-06 19:58 by curated_loader • Official label states Solensia is for use in cats.
usage updated 2026-08-06 19:58 by curated_loader • Official indication from the Solensia label.
drug_profile_type updated 2026-08-06 19:58 by curated_loader • Solensia is the branded FDA-approved animal drug for frunevetmab injection.
manufacturer_name updated 2026-08-06 19:58 by curated_loader • Official Solensia label identifies Zoetis as the labeler/manufacturer.
brand_names updated 2026-08-06 19:58 by curated_loader • Official label identifies Solensia as the proprietary product name.
approval_reference updated 2026-08-06 19:58 by curated_loader • Official FDA application reference for Solensia.
monitoring updated 2026-08-05 10:11 by curated_loader • Monitoring summary based on official label adverse-reaction and administration sections.
contraindications updated 2026-08-05 10:11 by curated_loader • Official contraindication from the Solensia label.
prescription_required updated 2026-08-05 10:11 by curated_loader • Federal law restricts Solensia to use by or on the order of a licensed veterinarian.
administration updated 2026-08-05 10:11 by curated_loader • Official dosage and administration directions from the Solensia label.
strengths updated 2026-08-05 10:11 by curated_loader • Official label lists Solensia as 7 mg/mL frunevetmab injection.
dosage_forms updated 2026-08-05 10:11 by curated_loader • Official label describes Solensia as frunevetmab injection.
species updated 2026-08-05 10:11 by curated_loader • Official label states Solensia is for use in cats.
usage updated 2026-08-05 10:11 by curated_loader • Official indication from the Solensia label.

FDA Products & Applications (Animal Drugs @ FDA)

Official sponsor/proprietary-name/application-status records linked by active ingredient.

Product	Sponsor	Application	Status	Published
Solensia™ RX Frunevetmab Injectable Solution • Subcutaneous Label highlights Official documents	Zoetis Inc.	NADA 141-546	Approved	May 14, 2026

Data source: FDA Animal Drugs @ FDA (public search export).

What It's For (FDA Label Highlights)

Extracted from FDA Animal Drugs @ FDA product labeling. Always confirm details with your veterinarian.

Species: Cat

Composition / specifications

7 mg/mL

Label highlights

Indication

For the control of pain associated with osteoarthritis in cats.

Dosage

The full content of 1 or 2 vials based on body weight to target a minimum dosage of 0.45 mg/lb. (1 mg/kg) body weight, administered subcutaneously once a month.

Limitations

FDA page: Open in Animal Drugs @ FDA

Usage

For the control of pain associated with osteoarthritis in cats.

Source: FDA Animal Drugs @ FDA • Reference

Top Reported Reactions (openFDA)

De-duplicated reaction terms grouped by body system from FDA openFDA reports (not verified; does not prove causation).

Digestive

Loss of appetite (1) • Dog

Showing top 5 for Digestive.

Skin & allergy

Hair loss (1) • Cat Alopecia NOS (1) • Cat Alopecia local (1) • Cat

Showing top 5 for Skin & allergy.

Neurologic

Unsteady walking (1) • Cat

Showing top 5 for Neurologic.

Behavior

Behavioral disorder (1) • Cat

Showing top 5 for Behavior.

Other

Blood clot (1) • Cat Blindness (1) • Cat Bladder distension (1) • Cat Basophilia (1) • Cat Barbering (1) • Cat

Show more (21)

Azotaemia (1) • Cat Ascites (1) • Cat Arthritis (1) • Cat Arrhythmia (1) • Cat Anisocoria (1) • Cat Anaphylaxis (1) • Cat Anaemia NOS (1) • Cat Agonal breathing (1) • Cat Agitation (1) • Cat Acute renal failure (1) • Cat Accidental exposure (1) • Cat Abrasion (1) • Cat Abnormal ultrasound finding (1) • Cat Abnormal radiograph finding (1) • Cat Abnormal posture NOS (1) • Cat Abnormal movement NOS (1) • Cat Abnormal menace reflex test (1) • Cat Abnormal histology NOS (1) • Cat Abnormal cytology (1) • Cat Abnormal breathing (1) • Cat Abdominal pain (1) • Cat

Showing top 5 for Other.

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Adverse Event Case Summaries (openFDA)

These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.

Cat, Domestic Shorthair, Female, 11 year, 3.992 kilogram • Drug: MSK, Solution, Subcutaneous, Dose: 7 Milligram per animal • Reactions: Facial pruritus, Medication error NOS • Outcome: Recovered/Normal

Report ID: USA-USFDACVM-2026-US-014454
Serious AE: No
Treated For AE: No
Sex: Female
Age: 11.00 Year
Weight: 3.992 Kilogram

Case-reported brand: MSK
Case-reported manufacturer: MSK
Route: Subcutaneous
Form: Solution
Dose: 7 Milligram per animal

Reactions Reported:

Facial pruritus Medication error NOS

Outcomes: Recovered/Normal

Cat, Cat (other), Female, 17 year • Drug: MSK, Solution, Subcutaneous • Reactions: Acute renal failure, Listless • Outcome: Recovered/Normal

Report ID: USA-USFDACVM-2026-US-014418
Serious AE: Yes
Treated For AE: Yes
Sex: Female
Age: 17.00 Year

Case-reported brand: MSK
Case-reported manufacturer: MSK
Route: Subcutaneous
Form: Solution

Reactions Reported:

Acute renal failure Listless

Outcomes: Recovered/Normal

Cat, Cat (other), Male, 12.5 year, 8.278 kilogram • Drug: MSK, Solution, Subcutaneous, Dose: 2 Vial per animal • Reactions: Weakness, Unsteady walking (ataxia), Gait abnormality, Luxation/subluxation, Joint pain… • Outcome: Ongoing

Report ID: USA-USFDACVM-2026-US-014416
Serious AE: Yes
Treated For AE: Yes
Sex: Male
Age: 12.50 Year
Weight: 8.278 Kilogram

Case-reported brand: MSK
Case-reported manufacturer: MSK
Route: Subcutaneous
Form: Solution
Dose: 2 Vial per animal

Reactions Reported:

Weakness Unsteady walking (ataxia) Gait abnormality Luxation/subluxation Joint pain Abnormal breathing Spondylosis

Outcomes: Ongoing

Cat, Domestic Shorthair, Female, 4 year • Drug: MSK, Solution, Subcutaneous, Dose: 7 Milligram per animal • Reactions: Constipation • Outcome: Ongoing

Report ID: USA-USFDACVM-2026-US-014414
Serious AE: No
Treated For AE: No
Sex: Female
Age: 4.00 Year

Case-reported brand: MSK
Case-reported manufacturer: MSK
Route: Subcutaneous
Form: Solution
Dose: 7 Milligram per animal

Reactions Reported:

Constipation

Outcomes: Ongoing

Cat, Domestic Mediumhair, Female, 19 year, 5.053 kilogram • Drug: MSK, Solution, Subcutaneous, Dose: 7 Milligram per animal • Reactions: Hind limb paralysis, Musculoskeletal disorder NOS, Urinary incontinence, Proprioception loss • Outcome: Ongoing

Report ID: USA-USFDACVM-2026-US-014412
Serious AE: Yes
Treated For AE: Yes
Sex: Female
Age: 19.00 Year
Weight: 5.053 Kilogram

Case-reported brand: MSK
Case-reported manufacturer: MSK
Route: Subcutaneous
Form: Solution
Dose: 7 Milligram per animal

Reactions Reported:

Hind limb paralysis Musculoskeletal disorder NOS Urinary incontinence Proprioception loss

Outcomes: Ongoing

Cat, Domestic Mediumhair, Male, 13 year, 5.897 kilogram • Drug: MSK, Solution, Subcutaneous, Dose: 7 Milligram per animal, Frequency: 1 per month • Reactions: Skin scab • Outcome: Recovered/Normal

Report ID: USA-USFDACVM-2026-US-014388
Serious AE: Yes
Treated For AE: Yes
Sex: Male
Age: 13.00 Year
Weight: 5.897 Kilogram

Case-reported brand: MSK
Case-reported manufacturer: MSK
Route: Subcutaneous
Form: Solution
Dose: 7 Milligram per animal
Frequency: 1 per month

Reactions Reported:

Skin scab

Outcomes: Recovered/Normal

Cat, Domestic Shorthair, Female, 14 year, 6.895 kilogram • Drug: MSK, Solution, Subcutaneous, Dose: 7 Milligram per animal • Reactions: Licking, Localised hair loss, Skin scab, Elevated creatine-kinase, Medication error NOS • Outcome: Ongoing

Report ID: USA-USFDACVM-2026-US-014453
Serious AE: No
Treated For AE: No
Sex: Female
Age: 14.00 Year
Weight: 6.895 Kilogram

Case-reported brand: MSK
Case-reported manufacturer: MSK
Route: Subcutaneous
Form: Solution
Dose: 7 Milligram per animal

Reactions Reported:

Licking Localised hair loss Skin scab Elevated creatine-kinase Medication error NOS

Outcomes: Ongoing

Cat, Domestic Shorthair, Female, 20 year, 2.631 kilogram • Drug: MSK, Solution, Subcutaneous, Dose: 7 Milligram per animal, Frequency: 1 per month • Reactions: Agitation, Vocalisation, Unsteady walking (ataxia), Weakness • Outcome: Recovered/Normal

Report ID: USA-USFDACVM-2026-US-014011
Serious AE: Yes
Treated For AE: Yes
Sex: Female
Age: 20.00 Year
Weight: 2.631 Kilogram

Case-reported brand: MSK
Case-reported manufacturer: MSK
Route: Subcutaneous
Form: Solution
Dose: 7 Milligram per animal
Frequency: 1 per month

Reactions Reported:

Agitation Vocalisation Unsteady walking (ataxia) Weakness

Outcomes: Recovered/Normal

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Overdose Information

No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.

Storage & Handling

No approved storage guidance is linked yet for this ingredient. Use manufacturer packaging and veterinary guidance for handling/storage.

Share Your Thoughts

Let others know your experience or advice regarding this medication.

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Frunevetmab

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Frunevetmab

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Frunevetmab

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