Gabapentin administration tips
How owners can administer doses safely.
Roxee Medication Guide
Gabapentin
Medication reference facts with explicit FDA-approval, off-label, source-limited, and safety context. Roxee does not sell, prescribe, or dispense medications.
Both
Reference partial
Not FDA-approved for animals
Multiple FDA labelers
Official label facts
Owner quick guide first
Veterinary professional?
Showing simplified owner view. Switch to Vet View for full technical detail.
Some reference facts for this medication are still being verified.
Not FDA-approved as an animal drug.
No FDA-approved animal-drug application is linked for this record. It may represent extra-label, human-drug, bulk-compounding, export-only, or otherwise unapproved animal-use source data; use only under veterinarian direction.
Do not start, stop, or change treatment without your veterinarian.
Data freshness
Reference facts
Reference refreshed
Aug 6, 2026, 7:47 p.m.
Roxee has a partial reference profile for this medication. Some primary facts still need verification.
FDA applications
FDA application data refreshed
Aug 6, 2026, 7:47 p.m.
Sponsor, product, and application records imported from Animal Drugs @ FDA.
Safety reports
Safety data refreshed
Aug 6, 2026, 7:49 p.m.
openFDA reaction terms and case summaries are supporting evidence, not proof of causality.
Source timing details
Source timing details
-
Reference facts:
Source Roxee
| Refreshed Aug 6, 2026, 7:47 PM UTC
The reference fact projection used for browse cards and quick facts.
-
Animal Drug Product Listing Directory (NDC):
Source FDA
| Refreshed Aug 6, 2026, 7:47 PM UTC
Package/product NDCs from FDA’s electronic listing directory (XLS).
- openFDA reaction terms: Source FDA openFDA | Refreshed Aug 6, 2026, 7:52 PM UTC
- openFDA case summaries: Source FDA openFDA | Refreshed Aug 6, 2026, 7:52 PM UTC
Illustration placeholder
Gabapentin
Gabapentin
Drug type: Generic ingredient • Branded profile • Not FDA-approved for animals
Both
86% reference complete
Species: Both
Approval status: Not FDA-approved as an animal drug. No FDA-approved animal-drug application is linked for this record. It may represent extra-label, human-drug, bulk-compounding, export-only, or otherwise unapproved animal-use source data; use only under veterinarian direction.
Medication Snapshot
Merged from the current Roxee medication system with field-level provenance, freshness, and completeness tracking.
Gabapentin
Used for neuropathic pain and as an adjunct for seizure control; also used for situational anxiety/sedation in some cases. Species commonly shown: Both.
Generic name
Gabapentin
Brand names
GABAPENTIN, SolutitionKits
Manufacturer
Multiple FDA labelers
Species
Both
Completeness
86%
Validation
Incomplete
Brand names
GABAPENTIN
SolutitionKits
Indications / Uses
Used for neuropathic pain and as an adjunct for seizure control; also used for situational anxiety/sedation in some cases.
Administration / How To Give
Oral
Storage
Store at room temperature.
Warnings / Contraindications
Use caution with kidney disease; dose adjustments may be needed.
- Use caution with kidney disease; dose adjustments may be needed.
Side Effects
Sedation, ataxia, mild GI upset.
FAQ
Both
Store at room temperature.
Related Medications
Related Conditions
Source Transparency
- Verified source: https://www.roxee.ai/meds/
- Verified source: https://animaldrugsatfda.fda.gov
- Verified source: https://animaldrugsatfda.fda.gov/adafda/views/#/search
- Verified source: https://api.fda.gov/animalandveterinary/event.json
- Verified source: https://www.roxee.ai/conditions/
- Verified source: /static/meds/images/gabapentin.jpg
- Last refreshed: Aug 6, 2026, 7:47 p.m.
- Last verified: Apr 15, 2026, 10:04 a.m.
- Validation status: Incomplete
Add to My Pet's Medications
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Sign in to continuePet Owner Quick Guide
Start here first for the safest next-step summary before the deeper medication detail.
Used for:
Used for neuropathic pain and as an adjunct for seizure control; also used for situational anxiety/sedation in some cases.
Dosing note:
Exact dosing depends on your pet's species, weight, and health status. Use your veterinarian's instructions for the exact dose and schedule.
What to watch for:
- Use caution with kidney disease
- dose adjustments may be needed
- Thrombocytopenia (4 reports)
- Elevated symmetrical dimethylarginine (4 reports)
- Conjunctivitis (3 reports)
When to call the vet:
- Repeated vomiting or diarrhea.
- Severe lethargy (hard to wake, very low energy).
- Collapse or fainting.
- Trouble breathing.
- Facial swelling or hives.
- Blood in vomit or stool.
What to tell or ask your vet today:
- Is this medicine the right fit for my pet’s current symptoms?
- Which warning signs mean I should call back right away?
- How should I handle missed doses or refusal to take the medicine?
Research brief
Medication Research Insights
A source-aware map of what to know, what is uncertain, and what to verify with your veterinarian.
What to know
Evidence-backed context
Limited
Roxee has limited cited overview evidence for Gabapentin; use the official documents and your veterinarian's instructions for product-specific decisions.
Source: openFDA reaction aggregate term
Safety signal coverage
Reported signals
32 tracked reaction signals; 60 reported cases; 7 serious reports; 2 species groups. These are reporting and label-derived signals for interpretation with a veterinarian.
Source: openFDA reaction aggregate term
Interpretation guardrail
Not causation
Adverse-event reports help form a watch list, but they do not prove the medication caused the reaction and they are not a risk ranking between medications.
Evidence tension
Stronger signal
Label / review
Official labels, package inserts, and reviewed summaries carry more weight than isolated reports.
Source: openFDA reaction aggregate term
Weaker signal
Reported data
Case reports and openFDA terms are useful for pattern awareness, but they are incomplete, can include multiple exposures, and do not estimate an individual pet's probability of harm.
Reaction signal map
Most reported reactions
Top terms
Thrombocytopenia (4 reports), Elevated symmetrical dimethylarginine (4 reports), Conjunctivitis (3 reports), Urolithiasis (2 reports), Unclassifiable adverse event (2 reports)
Body systems represented
Signal grouping
Effectiveness (1), Other (31)
Species and breed lens
Species represented in reports
Species lens
Dog (48 reports), Cat (12 reports)
Breed metadata in reports
Metadata only
Domestic Shorthair (2), Retriever - Labrador (2), Schnauzer - Miniature (1), Crossbred Canine/dog (1). These are report metadata, not proof that a breed is at higher risk.
What your vet may verify
Fit for this patient
Vet check
Verify whether Gabapentin fits the pet's species, current diagnosis, age, weight, organ status, pregnancy/lactation status, and concurrent medications.
Evidence limitations
Evidence review
Separate label-backed warnings from adverse-event reports and owner observations before changing the plan.
What to watch next
Watch list
Owner-safe
Use caution with kidney disease, dose adjustments may be needed, Thrombocytopenia, Elevated symmetrical dimethylarginine, Conjunctivitis
Call sooner if
Escalation
Repeated vomiting or diarrhea. Severe lethargy (hard to wake, very low energy). Collapse or fainting.
Bottom line: Use this Gabapentin brief as a structured watch list and source map, not as a reason to start, stop, or change treatment without your veterinarian.
Vet source depth
- openFDA reaction aggregate term · adverse_reaction · adverse reactions
- Medication contraindications · safety_warning · warnings contraindications
- Structured Product Label · document · documents
- Structured Product Label · document · documents
- Structured Product Label · document · documents
- Structured Product Label · document · documents
Evidence
Review status / Updated / Sources
Review status: Clinical reviewer not listed
Updated: April 15, 2026, 10:04 AM UTC
Sources:
- Medication contraindications · safety_warning
- openFDA reaction aggregate term · adverse_reaction
- Structured Product Label · document
- Structured Product Label · document
- Structured Product Label · document
Safety & side effects
Side effects to monitor:
- Use caution with kidney disease
- dose adjustments may be needed
- Thrombocytopenia
- Elevated symmetrical dimethylarginine
- Conjunctivitis
Most reported reactions:
- Thrombocytopenia (4 reports)
- Elevated symmetrical dimethylarginine (4 reports)
- Conjunctivitis (3 reports)
Emergency warning signs:
- Repeated vomiting or diarrhea.
- Severe lethargy (hard to wake, very low energy).
- Collapse or fainting.
- Trouble breathing.
Videos
Video education and manufacturer materials for Gabapentin.
Educational Videos
Manufacturer Videos
Gabapentin manufacturer spotlight
Promotional
Disclosure:
Manufacturer-linked promotional content. Educational sections should be prioritized for clinical context.
Manufacturer-provided informational segment.
Vet Fast Scan
Source-backed clinical checkpoints for quick review.
FDA-labeled species
Not linked yet
Indication / use
Used for neuropathic pain and as an adjunct for seizure control; also used for situational anxiety/sedation in some cases.
Form / route / dose
Confirm product label and patient-specific plan.
Warnings
- High: Use caution with kidney disease; dose adjustments may be needed.
Adverse-event caveat
openFDA adverse-event cases are reported signals. They are not verified, do not prove causation, and do not estimate a pet's individual risk.
Source docs
- Gabapentin SPL SPL
- Gabapentin SPL SPL
- SolutitionKits SPL SPL
Quick Facts
Official label facts first, then secondary summaries. Marketing content is separated below.
Species: Both
Manufacturer: Multiple FDA labelers
Identifiers:
NDC Package: 46144-600-01
NDC Package: 62157-711-01
NDC Package: 73377-176-01
NDC Package: 86032-041-01
NDC Product: 46144
NDC Product: 62157
NDC Product: 73377
NDC Product: 86032
Warnings / Contraindications
Use caution with kidney disease; dose adjustments may be needed.
- High: Use caution with kidney disease; dose adjustments may be needed.
Source metadata:
- https://animaldrugsatfda.fda.gov · safety_warning · Medication contraindications
Adverse Reactions
Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.
Reported case explorer
Filter stored openFDA reports by pet and report attributes. Counts describe reports in this data set, not risk.
openFDA adverse-event cases are reported signals. They are not verified, do not prove causation, and do not estimate a pet's individual risk.
Stored reports
164
Matching reports
164
Active filters
0
Drill into common report signals
Showing up to 50 matching reports.
Narrow filters to inspect the remaining reports.
USA-USFDACVM-2026-US-014454
Received 2026-03-26 · MSK · MSK
- Species
- Cat
- Breed
- Domestic Shorthair
- Size / weight
- Under 10 lb (3.992 Kilogram)
- Age
- 8+ years (11 Year)
- Sex
- Female Unknown
- Region
- USA
- Reactions
- Facial pruritusMedication error NOS
- Body systems
- Skin & allergyOther
- Outcomes
- Recovered/Normal
USA-USFDACVM-2026-US-014361
Received 2026-03-26 · MSK · MSK
- Species
- Dog
- Breed
- Retriever - Labrador
- Size / weight
- 100+ lb (47.174 Kilogram)
- Age
- 8+ years (11 Year)
- Sex
- Male Neutered
- Region
- USA
- Reactions
- Partial lack of efficacy
- Body systems
- Effectiveness
- Outcomes
- Ongoing
USA-USFDACVM-2026-US-014449
Received 2026-03-25 · MSK · MSK
- Species
- Dog
- Breed
- Schnauzer - Miniature
- Size / weight
- 10-24 lb (10.16 Kilogram)
- Age
- 4-7 years (5 Year)
- Sex
- Male Neutered
- Region
- USA
- Reactions
- LamenessWobblinessLethargy (see also Central nervous system depression in Neurological)Unable to walkWeaknessFeverImmune-mediated polyarthritisGastritisAbdominal cavity disorder NOSAbnormal ultrasound findingHyperproteinaemiaLymphopeniaEosinopeniaMedication error NOS
- Body systems
- OtherNeurologic
- Outcomes
- Ongoing
USA-USFDACVM-2026-US-014374
Received 2026-03-25 · MSK · MSK
- Species
- Dog
- Breed
- Crossbred Canine/dog
- Size / weight
- 50-99 lb (32.205 Kilogram)
- Age
- 8+ years (1 Year)
- Sex
- Male Neutered
- Region
- USA
- Reactions
- Musculoskeletal disorder NOSAggressionUnable to walkUrinary incontinenceMelaenaEmesis (multiple)Lethargy (see also Central nervous system depression in Neurological)Death by euthanasiaNeurological signs NOS
- Body systems
- OtherBehaviorDigestiveNeurologic
- Outcomes
- Euthanized
USA-USFDACVM-2026-US-014204
Received 2026-03-25 · MSK · MSK
- Species
- Dog
- Breed
- Retriever - Labrador
- Sex
- Unknown Unknown
- Region
- USA
- Reactions
- Death
- Body systems
- Other
- Outcomes
- Died
USA-USFDACVM-2026-US-014011
Received 2026-03-25 · MSK · MSK
- Species
- Cat
- Breed
- Domestic Shorthair
- Size / weight
- Under 10 lb (2.631 Kilogram)
- Age
- 8+ years (2 Year)
- Sex
- Female Unknown
- Region
- USA
- Reactions
- AgitationVocalisationAtaxiaWeakness
- Body systems
- OtherNeurologic
- Outcomes
- Recovered/Normal
USA-USFDACVM-2026-US-014065
Received 2026-03-24 · MSK · MSK
- Species
- Dog
- Breed
- Retriever - Golden
- Size / weight
- 50-99 lb (34.019 Kilogram)
- Age
- 4-7 years (4 Year)
- Sex
- Female Unknown
- Region
- USA
- Reactions
- LamenessDifficulty to riseJoint swellingAbnormal radiograph findingBone and joint disorder NOSDiscomfort NOS
- Body systems
- OtherSkin & allergy
- Outcomes
- Ongoing
USA-USFDACVM-2026-US-014048
Received 2026-03-24 · MSK · MSK
- Species
- Dog
- Breed
- Shepherd Dog - German
- Size / weight
- 50-99 lb (35.698 Kilogram)
- Age
- 8+ years (9 Year)
- Sex
- Female Unknown
- Region
- USA
- Reactions
- Joint painLamenessDepressionDifficulty standingDecreased appetiteAbnormal radiograph findingBone and joint disorder NOSJoint effusionSpondylosis
- Body systems
- OtherNeurologicDigestive
- Outcomes
- Outcome Unknown
USA-USFDACVM-2026-US-013826
Received 2026-03-24 · MSK · MSK
- Species
- Dog
- Breed
- Chihuahua
- Size / weight
- Under 10 lb (4.173 Kilogram)
- Age
- 8+ years (12 Year)
- Sex
- Female Unknown
- Region
- USA
- Reactions
- Luxation/subluxationLack of efficacy - NOSJoint swellingBone and joint disorder NOSPain NOSLamenessHyperextension
- Body systems
- OtherEffectivenessSkin & allergy
- Outcomes
- Ongoing
USA-USFDACVM-2026-US-013782
Received 2026-03-24 · MSK · MSK
- Species
- Dog
- Breed
- Spaniel - Springer (unspecified)
- Size / weight
- 50-99 lb (25.855 Kilogram)
- Age
- 8+ years (11 Year)
- Sex
- Male Intact
- Region
- USA
- Reactions
- Musculoskeletal disorder NOSCentral nervous system disorder NOSPeripheral nervous system disorder NOSBone and joint disorder NOSSkin disorders NOSNeurological signs NOS
- Body systems
- OtherNeurologic
- Outcomes
- Outcome Unknown
USA-USFDACVM-2026-US-013761
Received 2026-03-24 · MSK · MSK
- Species
- Cat
- Breed
- Domestic Longhair
- Size / weight
- Under 10 lb (2.781 Kilogram)
- Age
- Under 1 year (5 Month)
- Sex
- Male Neutered
- Region
- USA
- Reactions
- Increased respiratory rateBreathing difficultyCrackles on auscultationAbnormal ultrasound findingPulmonary disorder NOSIntentional misuseDecreased pulse oxygenationPale mucous membrane
- Body systems
- Other
- Outcomes
- Ongoing
USA-USFDACVM-2026-US-013511
Received 2026-03-24 · MSK · MSK
- Species
- Dog
- Breed
- Retriever - Golden
- Size / weight
- 50-99 lb (34.473 Kilogram)
- Age
- 8+ years (11 Year)
- Sex
- Female Unknown
- Region
- USA
- Reactions
- Lack of efficacy - NOS
- Body systems
- Effectiveness
- Outcomes
- Ongoing
USA-USFDACVM-2026-US-013796
Received 2026-03-23 · MSK · MSK
- Species
- Dog
- Breed
- Samoyed
- Size / weight
- 50-99 lb (30.391 Kilogram)
- Age
- 8+ years (13 Year)
- Sex
- Female Unknown
- Region
- USA
- Reactions
- Limb weaknessMusculoskeletal disorder NOSAbnormal movement NOS
- Body systems
- Other
- Outcomes
- Recovered/Normal
USA-USFDACVM-2026-US-013509
Received 2026-03-23 · MSK · MSK
- Species
- Dog
- Breed
- ['Terrier - Bull - American Pit', 'Dog (unknown)']
- Size / weight
- 25-49 lb (21.863 Kilogram)
- Age
- 8+ years (13 Year)
- Sex
- Female Unknown
- Region
- USA
- Reactions
- Elevated creatinineInappropriate urinationPolyuriaInappropriate defecationUrinary incontinenceTail paralysisStranguriaArthritisSpondylosis
- Body systems
- Other
- Outcomes
- Ongoing
USA-USFDACVM-2026-US-013464
Received 2026-03-23 · MSK · MSK
- Species
- Cat
- Breed
- Domestic Shorthair
- Size / weight
- 10-24 lb (6.169 Kilogram)
- Age
- 8+ years (16 Year)
- Sex
- Female Unknown
- Region
- USA
- Reactions
- Injection site mass NOSAbnormal radiograph findingFibrosarcoma
- Body systems
- Other
- Outcomes
- Ongoing
USA-USFDACVM-2026-US-013427
Received 2026-03-20 · MSK · MSK
- Species
- Dog
- Breed
- Retriever - Golden
- Size / weight
- 50-99 lb (23.315 Kilogram)
- Age
- 8+ years (13 Year)
- Sex
- Female Unknown
- Region
- USA
- Reactions
- Urinary tract infectionLymphadenopathyElevated globulinsAbnormal cytology
- Body systems
- Other
- Outcomes
- Ongoing
USA-USFDACVM-2026-US-013334
Received 2026-03-20 · MSK · MSK
- Species
- Dog
- Breed
- Retriever - Labrador
- Size / weight
- 50-99 lb (42.8 Kilogram)
- Age
- 8+ years (8 Year)
- Sex
- Female Neutered
- Region
- USA
- Reactions
- Lack of efficacy - NOS
- Body systems
- Effectiveness
- Outcomes
- Outcome Unknown
USA-USFDACVM-2026-US-012947
Received 2026-03-20 · MSK · MSK
- Species
- Dog
- Breed
- ['Hound - Basset', 'Dog (unknown)']
- Size / weight
- 25-49 lb (18.597 Kilogram)
- Age
- 8+ years (12.67 Year)
- Sex
- Male Neutered
- Region
- USA
- Reactions
- Elevated cholesterol (total)Elevated serum alkaline phosphatase (ALP)HyposthenuriaParaphimosisLimb weaknessAtaxia
- Body systems
- OtherNeurologic
- Outcomes
- Ongoing
USA-USFDACVM-2026-US-012798
Received 2026-03-20 · MSK · MSK
- Species
- Dog
- Breed
- Crossbred Canine/dog
- Size / weight
- 25-49 lb (14.969 Kilogram)
- Age
- 1-3 years (1 Year)
- Sex
- Female Unknown
- Region
- USA
- Reactions
- VocalisationRestlessnessIntentional misuse
- Body systems
- Other
- Outcomes
- Ongoing
USA-USFDACVM-2026-US-013633
Received 2026-03-19 · MSK · MSK
- Species
- Cat
- Breed
- Domestic Shorthair
- Size / weight
- 10-24 lb (5.33 Kilogram)
- Age
- 8+ years (11 Year)
- Sex
- Female Neutered
- Region
- USA
- Reactions
- DysphoriaBehavioural disorder NOSDilated pupilsAnorexiaSkin and tissue infection NOSLethargy (see also Central nervous system depression in Neurological)
- Body systems
- OtherBehaviorDigestiveNeurologic
- Outcomes
- Recovered/Normal
USA-USFDACVM-2026-US-013423
Received 2026-03-19 · MSK · MSK
- Species
- Dog
- Breed
- Terrier - Bull - American Pit
- Size / weight
- 50-99 lb (24.948 Kilogram)
- Age
- 8+ years (13 Year)
- Sex
- Female Unknown
- Region
- USA
- Reactions
- WobblinessDisorientationGeneral illnessLimb weaknessDeath by euthanasia
- Body systems
- Other
- Outcomes
- Euthanized
USA-USFDACVM-2026-US-013262
Received 2026-03-19 · MSK · MSK
- Species
- Cat
- Breed
- Persian
- Size / weight
- Under 10 lb (4.08 Kilogram)
- Age
- 4-7 years (4 Year)
- Sex
- Male Neutered
- Region
- USA
- Reactions
- Laboured breathingAnorexia
- Body systems
- OtherDigestive
- Outcomes
- Recovered/Normal
USA-USFDACVM-2026-US-013169
Received 2026-03-19 · MSK · MSK
- Species
- Dog
- Breed
- Rottweiler
- Size / weight
- 50-99 lb (43.001 Kilogram)
- Age
- 8+ years (1 Year)
- Sex
- Male Neutered
- Region
- USA
- Reactions
- Musculoskeletal disorder NOSCollapse NOS (see also Cardio-vascular and Neurological disorders)Lethargy (see also Central nervous system depression in Neurological)Unable to walkNot eatingWeaknessDeath
- Body systems
- OtherNeurologic
- Outcomes
- Died
USA-USFDACVM-2026-US-012950
Received 2026-03-19 · MSK · MSK
- Species
- Cat
- Breed
- Domestic Shorthair
- Size / weight
- Under 10 lb (3.148 Kilogram)
- Age
- 8+ years (17 Year)
- Sex
- Male Neutered
- Region
- USA
- Reactions
- Immediate pain upon injectionMedication error NOS
- Body systems
- Other
- Outcomes
- Recovered/Normal
USA-USFDACVM-2026-US-012895
Received 2026-03-19 · MSK · MSK
- Species
- Dog
- Breed
- Shepherd Dog - German
- Size / weight
- 50-99 lb (30.844 Kilogram)
- Age
- 4-7 years (4 Year)
- Sex
- Female Unknown
- Region
- USA
- Reactions
- Injection site painInjection site swellingEmesis (multiple)Decreased appetitePica NOSLocalised pain NOS (see other SOCs for specific pain)Eosinophilia
- Body systems
- OtherSkin & allergyDigestive
- Outcomes
- Ongoing
USA-USFDACVM-2026-US-013220
Received 2026-03-17 · MSK · MSK
- Species
- Dog
- Breed
- ['Terrier - Bull - American Pit', 'Dog (unknown)']
- Age
- 8+ years (13 Year)
- Sex
- Male Neutered
- Region
- USA
- Reactions
- Head downWalking difficulty
- Body systems
- Other
- Outcomes
- Ongoing
USA-USFDACVM-2026-US-012892
Received 2026-03-17 · MSK · MSK
- Species
- Dog
- Breed
- Bloodhound
- Size / weight
- 100+ lb (68.492 Kilogram)
- Age
- 8+ years (8 Year)
- Sex
- Male Neutered
- Region
- USA
- Reactions
- LimpingPain NOSTorn ligamentJoint swellingBone and joint disorder NOSPlantigrade postureAbnormal radiograph findingMedication error NOS
- Body systems
- OtherSkin & allergy
- Outcomes
- Ongoing
USA-USFDACVM-2026-US-012815
Received 2026-03-17 · MSK · MSK
- Species
- Dog
- Breed
- ['Shar Pei', 'Akita', 'Siberian Husky']
- Size / weight
- 100+ lb (48.534 Kilogram)
- Age
- 8+ years (11 Year)
- Sex
- Male Neutered
- Region
- USA
- Reactions
- Hind limb ataxiaDeath by euthanasiaHind limb paresis
- Body systems
- NeurologicOther
- Outcomes
- Euthanized
USA-USFDACVM-2026-US-012782
Received 2026-03-17 · MSK · MSK
- Species
- Dog
- Breed
- Setter - English
- Size / weight
- 25-49 lb (21.772 Kilogram)
- Age
- 8+ years (9 Year)
- Sex
- Male Neutered
- Region
- USA
- Reactions
- Dilated renal pelvisIntestinal thickeningAbnormal ultrasound findingBradycardiaPale mucous membraneDiarrhoeaWeight lossLethargy (see also Central nervous system depression in Neurological)LymphomaMedication error NOS
- Body systems
- OtherDigestiveNeurologic
- Outcomes
- Ongoing
USA-USFDACVM-2026-US-013537
Received 2026-03-16 · MSK · MSK
- Species
- Cat
- Breed
- Domestic Longhair
- Size / weight
- Under 10 lb (4.47 Kilogram)
- Age
- 4-7 years (7 Year)
- Sex
- Female Neutered
- Region
- USA
- Reactions
- Localised hair lossReddening of the skinItchy skinWoundDermal thickeningAbnormal cytologyIntentional misuseLocal swelling (not application site)Reverse sneezingLeukocytosis NOSThrombocytopeniaNeutrophiliaMonocytosisSkin lesion NOS
- Body systems
- Skin & allergyOther
- Outcomes
- Ongoing
USA-USFDACVM-2026-US-013313
Received 2026-03-16 · MSK · MSK
- Species
- Cat
- Breed
- Domestic Shorthair
- Size / weight
- 10-24 lb (6.427 Kilogram)
- Age
- 8+ years (13 Year)
- Sex
- Female Neutered
- Region
- USA
- Reactions
- PruritusSkin lesion NOSSkin scab
- Body systems
- Skin & allergyOther
- Outcomes
- Ongoing
USA-USFDACVM-2026-US-013278
Received 2026-03-16 · MSK · MSK
- Species
- Cat
- Breed
- Domestic Mediumhair
- Size / weight
- 10-24 lb (6.8 Kilogram)
- Age
- 8+ years (9 Year)
- Sex
- Male Neutered
- Region
- USA
- Reactions
- Injection site cystInjection site sarcomaInjection site lumpInjection site discharge NOSInjection site irritationLethargy (see also Central nervous system depression in Neurological)Elevated symmetrical dimethylarginine (SDMA)HypoalbuminaemiaThrombocytosisHyperkalaemiaAbnormal radiograph findingConstipationPain NOSAbnormal cytologyDecreased appetiteLicking at injection site
- Body systems
- OtherNeurologicDigestive
- Outcomes
- Ongoing
USA-USFDACVM-2026-US-013265
Received 2026-03-16 · MSK · MSK
- Species
- Dog
- Breed
- Corso Dog
- Size / weight
- 50-99 lb (42.184 Kilogram)
- Age
- 1-3 years (1 Year)
- Sex
- Female Neutered
- Region
- USA
- Reactions
- Lethargy (see also Central nervous system depression in Neurological)Not eatingFeverInjection site lumpApplication site serous discharge
- Body systems
- NeurologicOther
- Outcomes
- Ongoing
USA-USFDACVM-2026-US-013066
Received 2026-03-16 · MSK · MSK
- Species
- Dog
- Breed
- Samoyed
- Size / weight
- 50-99 lb (24.948 Kilogram)
- Age
- 8+ years (9 Year)
- Sex
- Male Neutered
- Region
- USA
- Reactions
- Lethargy (see also Central nervous system depression in Neurological)ShakingPale mucous membraneCold feeling of extremityVomitingTachycardiaLaboured breathingTachypnoeaDehydrationWeak pulseTense abdomenHypochloraemiaHyponatremiaAzotaemiaHypocalcaemiaHypoglycaemiaHyperphosphataemiaHypoproteinaemiaHypoalbuminaemiaLow alanine aminotransferase (ALT)Elevated lactateIncreased percentage reticulocytesLymphocytosisMonocytosisAbnormal red blood cellHypotensionAbdominal effusionAspiration pneumoniaHeart murmurGastric perforationLateral recumbencySepticaemiaCoagulopathyHypernatraemiaHypercalcaemiaElevated serum alkaline phosphatase (ALP)NeutrophiliaStridor (Upper respiratory; for lower respiratory see also Bronchial rale)Unresponsive to stimuliCyanotic mucous membranesThrombosisOedema of the extremities (see also other SOCs for most applicable oedema)Pitting oedemaLamenessElevated aspartate aminotransferase (AST)Stertor
- Body systems
- NeurologicOtherDigestive
- Outcomes
- Ongoing
USA-USFDACVM-2026-US-012963
Received 2026-03-16 · MSK · MSK
- Species
- Dog
- Breed
- Great Pyrenees
- Size / weight
- 50-99 lb (40.37 Kilogram)
- Age
- 8+ years (13 Year)
- Sex
- Male Unknown
- Region
- USA
- Reactions
- Vestibular disorder NOSAtaxiaNystagmusTympanic rupture
- Body systems
- OtherNeurologic
- Outcomes
- Ongoing
USA-USFDACVM-2026-US-012640
Received 2026-03-16 · MSK · MSK
- Species
- Dog
- Breed
- Chihuahua
- Size / weight
- Under 10 lb (2.54 Kilogram)
- Age
- 8+ years (8.25 Year)
- Sex
- Female Unknown
- Region
- USA
- Reactions
- Muscle tremorOpisthotonusRigidity of limbsStar-gazingProlonged anaesthesiaIntentional misuse
- Body systems
- NeurologicOther
- Outcomes
- Recovered/Normal
USA-USFDACVM-2026-US-012478
Received 2026-03-16 · MSK · MSK
- Species
- Dog
- Breed
- ['Retriever - Labrador', 'Terrier - Bull - American Pit']
- Size / weight
- 50-99 lb (31.298 Kilogram)
- Age
- 8+ years (14 Year)
- Sex
- Female Neutered
- Region
- USA
- Reactions
- Limb weaknessDecreased appetiteDeath by euthanasiaLethargy (see also Central nervous system depression in Neurological)Panting
- Body systems
- OtherDigestiveNeurologic
- Outcomes
- Euthanized
USA-USFDACVM-2026-US-012312
Received 2026-03-16 · MSK · MSK
- Species
- Dog
- Breed
- Terrier - Norfolk
- Size / weight
- 25-49 lb (12 Kilogram)
- Age
- 8+ years (12 Year)
- Sex
- Male Neutered
- Region
- USA
- Reactions
- Weight gain
- Body systems
- Other
- Outcomes
- Outcome Unknown
USA-USFDACVM-2026-US-013584
Received 2026-03-13 · MSK · MSK
- Species
- Dog
- Breed
- Crossbred Canine/dog
- Size / weight
- 25-49 lb (15.876 Kilogram)
- Age
- 8+ years (1 Year)
- Sex
- Female Neutered
- Region
- USA
- Reactions
- ItchingLicking
- Body systems
- Skin & allergyOther
- Outcomes
- Ongoing
USA-USFDACVM-2026-US-011996
Received 2026-03-13 · MSK · MSK
- Species
- Dog
- Breed
- Terrier - Bull - American Pit
- Size / weight
- 50-99 lb (29.937 Kilogram)
- Age
- 4-7 years (5 Year)
- Sex
- Male Neutered
- Region
- USA
- Reactions
- Injection site painAnorexiaFeverInjection site swellingInjection site abscessLethargy (see also Central nervous system depression in Neurological)
- Body systems
- OtherDigestiveSkin & allergyNeurologic
- Outcomes
- Ongoing
USA-USFDACVM-2026-US-011585
Received 2026-03-13 · MSK · MSK
- Species
- Dog
- Breed
- Collie - Smooth-haired
- Size / weight
- 50-99 lb (30.9 Kilogram)
- Age
- 8+ years (11 Year)
- Sex
- Female Unknown
- Region
- USA
- Reactions
- Generalised itchingIncreased drinkingPolyuria
- Body systems
- Skin & allergyOther
- Outcomes
- Ongoing
USA-USFDACVM-2026-US-014477
Received 2026-03-11 · MSK · MSK
- Species
- Dog
- Breed
- Dog (unknown)
- Sex
- Unknown Unknown
- Region
- USA
- Reactions
- Injection site pain
- Body systems
- Other
- Outcomes
- Outcome Unknown
USA-USFDACVM-2026-US-013136
Received 2026-03-11 · MSK · MSK
- Species
- Dog
- Breed
- Shepherd Dog - German
- Size / weight
- 50-99 lb (38.918 Kilogram)
- Age
- 4-7 years (5 Year)
- Sex
- Female Intact
- Region
- USA
- Reactions
- Swelling NOSLamenessBone and joint disorder NOSAbnormal radiograph finding
- Body systems
- Skin & allergyOther
- Outcomes
- Ongoing
USA-USFDACVM-2026-US-011895
Received 2026-03-11 · MSK · MSK
- Species
- Cat
- Breed
- Domestic Shorthair
- Size / weight
- Under 10 lb (4.377 Kilogram)
- Age
- 1-3 years (1.5 Year)
- Sex
- Female Unknown
- Region
- USA
- Reactions
- VomitingLocalised pain NOS (see other SOCs for specific pain)Limb non-weight bearingLethargy (see also Central nervous system depression in Neurological)Not eatingHead tremorIncreased respiratory ratePlantigrade postureLimb weaknessProprioception deficitCutaneous emphysemaAbnormal radiograph findingKnuckling
- Body systems
- DigestiveOtherNeurologic
- Outcomes
- Ongoing
USA-USFDACVM-2026-US-011648
Received 2026-03-10 · MSK · MSK
- Species
- Cat
- Breed
- Domestic Shorthair
- Size / weight
- 10-24 lb (5.126 Kilogram)
- Age
- 4-7 years (5 Year)
- Sex
- Female Neutered
- Region
- USA
- Reactions
- Emesis (multiple)Weight lossLethargy (see also Central nervous system depression in Neurological)Blood in vomitAbnormal ultrasound findingWeaknessDecreased appetiteINEFFECTIVE, ANTIEMETICDigestive tract disorder NOS
- Body systems
- DigestiveOtherNeurologic
- Outcomes
- Ongoing
USA-USFDACVM-2026-US-011382
Received 2026-03-10 · MSK · MSK
- Species
- Dog
- Breed
- Dog (unknown)
- Size / weight
- 25-49 lb (15.286 Kilogram)
- Age
- 8+ years (8 Year)
- Sex
- Male Neutered
- Region
- USA
- Reactions
- Lack of efficacy - NOSIntentional misuse
- Body systems
- EffectivenessOther
- Outcomes
- Ongoing
USA-USFDACVM-2026-US-010089
Received 2026-03-07 · MSK · MSK
- Species
- Cat
- Breed
- Domestic Shorthair
- Size / weight
- 10-24 lb (5.4 Kilogram)
- Age
- 8+ years (14 Year)
- Sex
- Male Neutered
- Region
- USA
- Reactions
- HypotensionBradycardiaHypernatraemiaLying downLethargy (see also Central nervous system depression in Neurological)Reduced responses
- Body systems
- OtherNeurologic
- Outcomes
- Recovered/Normal
USA-USFDACVM-2026-US-010873
Received 2026-03-04 · MSK · MSK
- Species
- Cat
- Breed
- Domestic Shorthair
- Size / weight
- 10-24 lb (4.98 Kilogram)
- Age
- 8+ years (9.91 Year)
- Sex
- Female Neutered
- Region
- USA
- Reactions
- Sedation prolongedIncreased respiratory rateOpen mouth breathingDeath by euthanasiaCardiac enlargementAdministration error NOS
- Body systems
- Other
- Outcomes
- Euthanized
USA-USFDACVM-2026-US-010748
Received 2026-03-04 · MSK · MSK
- Species
- Dog
- Breed
- ['Terrier - Bull - American Pit', 'Terrier - Bull - Staffordshire']
- Size / weight
- 25-49 lb (21.22 Kilogram)
- Age
- Under 1 year (9 Month)
- Sex
- Female Neutered
- Region
- USA
- Reactions
- Skin lumpSurgical site disorderSkin inflammation NOSReddening of the skinIntentional misuseApplication site irritationApplication site reddeningApplication site inflammationContamination NOS
- Body systems
- Other
- Outcomes
- Ongoing
USA-USFDACVM-2026-US-010347
Received 2026-03-03 · MSK · MSK
- Species
- Dog
- Breed
- ['Shepherd Dog - German', 'Retriever - Labrador']
- Size / weight
- 50-99 lb (29.166 Kilogram)
- Age
- 8+ years (1 Year)
- Sex
- Female Unknown
- Region
- USA
- Reactions
- LimpingMusculoskeletal disorder NOSLocal swelling (not application site)Hot spot (pyotraumatic dermatitis)LickingNot himself/herselfElevated serum alkaline phosphatase (ALP)Elevated blood urea nitrogen (BUN)Elevated creatinineNeutrophiliaDeathMedication error NOS
- Body systems
- OtherSkin & allergy
- Outcomes
- Died
Tap or hover a reaction to see what it means in plain language.
Tracked signals
32
Reported cases
60
Serious reports
7
Species represented
2
Grouped by Body System
Effectiveness (1)
· Lack of efficacy (endoparasite) - tapeworm
Other (31)
· Thrombocytopenia, Elevated symmetrical dimethylarginine, Conjunctivitis
Most Reported Reactions
| Reaction | Body system | Cases | Species | Serious cases |
|---|---|---|---|---|
| Other | 4 | Dog | 0 | |
| Other | 4 | Dog | 0 | |
| Other | 3 | Dog | 0 | |
| Other | 2 | Dog | 0 | |
| Other | 2 | Dog | 0 | |
| Other | 2 | Dog | 0 | |
| Other | 2 | Dog | 0 | |
| Other | 2 | Dog | 0 |
Species coverage: Dog (48) Cat (12)
View detailed reaction table
| Reaction | Body system | Species | Seriousness | Frequency | Reports |
|---|---|---|---|---|---|
| Other | Dog | Unknown | - | 4 | |
| Other | Dog | Unknown | - | 4 | |
| Other | Dog | Unknown | - | 3 | |
| Other | Dog | Unknown | - | 2 | |
| Other | Dog | Unknown | - | 2 | |
| Other | Dog | Unknown | - | 2 | |
| Other | Dog | Unknown | - | 2 | |
| Other | Dog | Unknown | - | 2 | |
| Other | Dog | Unknown | - | 2 | |
| Other | Dog | Unknown | - | 2 | |
| Other | Dog | Unknown | - | 2 | |
| Other | Dog | Unknown | - | 2 | |
| Effectiveness | Dog | Unknown | - | 2 | |
| Other | Dog | Unknown | - | 2 | |
| Other | Dog | Unknown | - | 2 | |
| Other | Cat | Unknown | - | 2 | |
| Other | Cat | Unknown | - | 2 | |
| Other | Dog | Unknown | - | 2 | |
| Other | Dog | Unknown | - | 2 | |
| Other | Cat | Unknown | - | 2 | |
| Other | Cat | Unknown | - | 2 | |
| Other | Cat | Unknown | - | 2 | |
| Other | Dog | Unknown | - | 2 | |
| Other | Cat | Serious | - | 1 | |
| Other | Dog | Non-serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Other | Dog | Unknown | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Dog | Serious | - | 1 |
Source metadata:
- https://api.fda.gov/animalandveterinary/event.json · adverse_reaction · openFDA reaction aggregate term
Storage & Handling
Store at room temperature.
Source Documents
The most useful source links appear first; full previews and metadata stay in the veterinary/professional layer.
Use original documents to confirm product-specific warnings, ingredients, and handling details with your veterinarian.
Gabapentin SPL
SPL · Structured Product Label
Gabapentin SPL
SPL · Structured Product Label
SolutitionKits SPL
SPL · Structured Product Label
Full source previews and metadata remain in the veterinary/professional layer.
Owner handouts
0No owner handouts linked yet.
Official label / PI
0No official label or package insert links yet.
SPL
4FOI
0No FOI links yet.
Gabapentin SPL
SPL · Structured Product Label
FDA Structured Product Label XML for Gabapentin. Use the source link for the full official labeling record.
Gabapentin SPL
SPL · Structured Product Label
FDA Structured Product Label XML for Gabapentin. Use the source link for the full official labeling record.
SolutitionKits SPL
SPL · Structured Product Label
FDA Structured Product Label XML for SolutitionKits. Use the source link for the full official labeling record.
GABAPENTIN SPL
SPL · Structured Product Label
FDA Structured Product Label XML for GABAPENTIN. Use the source link for the full official labeling record.
Source metadata:
- https://www.accessdata.fda.gov/spl/data/54945492-2e86-4f6d-99e0-d4f492ab0dc0/54945492-2e86-4f6d-99e0-d4f492ab0dc0.xml · document · Structured Product Label
- https://www.accessdata.fda.gov/spl/data/de14dc38-395f-420b-89b9-f3c57e195149/de14dc38-395f-420b-89b9-f3c57e195149.xml · document · Structured Product Label
- https://www.accessdata.fda.gov/spl/data/fc8d67a9-6118-481c-a1e4-53269e18b31d/fc8d67a9-6118-481c-a1e4-53269e18b31d.xml · document · Structured Product Label
- https://www.accessdata.fda.gov/spl/data/346c35fb-8599-4556-9804-a4452af8bb91/346c35fb-8599-4556-9804-a4452af8bb91.xml · document · Structured Product Label
Veterinary reference (advanced)
Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.
At a Glance
Quick facts and links to official labeling and safety signals.
Data freshness
-
Reference facts:
Source Roxee
| Refreshed Aug 6, 2026, 7:47 PM UTC
The reference fact projection used for browse cards and quick facts.
-
Animal Drug Product Listing Directory (NDC):
Source FDA
| Refreshed Aug 6, 2026, 7:47 PM UTC
Package/product NDCs from FDA’s electronic listing directory (XLS).
- openFDA reaction terms: Source FDA openFDA | Refreshed Aug 6, 2026, 7:52 PM UTC
- openFDA case summaries: Source FDA openFDA | Refreshed Aug 6, 2026, 7:52 PM UTC
Official (FDA)
Identity: Generic ingredient
• FDA branded products available
Official FDA brands:
GABAPENTIN
Gabapentin
SolutitionKits
Manufacturer mapping:
Multiple FDA labelers
Case-reported brands (openFDA):
MSK
Catalog species: Both
NDC:
Packages
46144-600-01
62157-711-01
73377-176-01
86032-041-01
•
Products
46144
62157
73377
86032
Explore
Related conditions:
Pain (acute, chronic)
Linked using:
Usage_Inferred (0.78)
Diagnosis Codes
Diagnosis-code mappings are not available for this medication yet.
Counseling and Monitoring Highlights
Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.
Owner-facing counseling points
- Use caution with kidney disease; dose adjustments may be needed. (Contraindication, High)
Top reaction signals
Thrombocytopenia (4)
Elevated symmetrical dimethylarginine (4)
Conjunctivitis (3)
Urolithiasis (2)
Unclassifiable adverse event (2)
Trembling (2)
Skin lesion NOS (2)
Respiratory tract infection NOS (2)
Identifiers & Packages
Normalized identifiers (NDC/NADA/ANADA) and package metadata from regulator listings.
Identifiers
NDC Package: 46144-600-01
NDC Package: 62157-711-01
NDC Package: 73377-176-01
NDC Package: 86032-041-01
NDC Product: 46144
NDC Product: 62157
NDC Product: 73377
NDC Product: 86032
| Package NDC | Product NDC | Form / Route | Status |
|---|---|---|---|
| 46144-600-01 | 46144 | - | |
| 62157-711-01 | 62157 | - | |
| 73377-176-01 | 73377 | - | |
| 86032-041-01 | 86032 | - |
Enriched Documents
Documents are tiered by source trust: Official, Clinical, Manufacturer, Marketing.
-
Gabapentin SPL
• Structured Product Label • Official
FDA Structured Product Label from the electronic animal drug product listing directory.
-
Gabapentin SPL
• Structured Product Label • Official
FDA Structured Product Label from the electronic animal drug product listing directory.
-
SolutitionKits SPL
• Structured Product Label • Official
FDA Structured Product Label from the electronic animal drug product listing directory.
-
GABAPENTIN SPL
• Structured Product Label • Official
FDA Structured Product Label from the electronic animal drug product listing directory.
Data Sources & Change Log
Every non-trivial field is expected to include provenance and update timestamps.
Official 4
Clinical 120
Manufacturer 0
Marketing 0
Marketing/Manufacturer content exists: 1 linked manufacturer ad video are attached to this medication.
Current Field Facts
- contraindications: Use caution with kidney disease; dose adjustments may be needed. (Clinical, 2026-07-22)
- contraindications: Use caution with kidney disease; dose adjustments may be needed. (Clinical, 2026-07-22)
- contraindications: Use caution with kidney disease; dose adjustments may be needed. (Clinical, 2026-07-22)
- contraindications: Use caution with kidney disease; dose adjustments may be needed. (Clinical, 2026-07-20)
- contraindications: Use caution with kidney disease; dose adjustments may be needed. (Clinical, 2026-07-19)
- contraindications: Use caution with kidney disease; dose adjustments may be needed. (Clinical, 2026-07-16)
- contraindications: Use caution with kidney disease; dose adjustments may be needed. (Clinical, 2026-07-16)
- contraindications: Use caution with kidney disease; dose adjustments may be needed. (Clinical, 2026-07-13)
- contraindications: Use caution with kidney disease; dose adjustments may be needed. (Clinical, 2026-07-12)
- contraindications: Use caution with kidney disease; dose adjustments may be needed. (Clinical, 2026-07-11)
- contraindications: Use caution with kidney disease; dose adjustments may be needed. (Clinical, 2026-07-11)
- contraindications: Use caution with kidney disease; dose adjustments may be needed. (Clinical, 2026-07-11)
- contraindications: Use caution with kidney disease; dose adjustments may be needed. (Clinical, 2026-07-10)
- contraindications: Use caution with kidney disease; dose adjustments may be needed. (Clinical, 2026-07-07)
- contraindications: Use caution with kidney disease; dose adjustments may be needed. (Clinical, 2026-07-06)
- contraindications: Use caution with kidney disease; dose adjustments may be needed. (Clinical, 2026-07-06)
- contraindications: Use caution with kidney disease; dose adjustments may be needed. (Clinical, 2026-07-03)
- contraindications: Use caution with kidney disease; dose adjustments may be needed. (Clinical, 2026-07-03)
- contraindications: Use caution with kidney disease; dose adjustments may be needed. (Clinical, 2026-07-02)
- contraindications: Use caution with kidney disease; dose adjustments may be needed. (Clinical, 2026-07-01)
Recent Revisions
- side_effects updated 2026-07-22 19:08 by etl_backfill • Backfilled from existing medication fields
- contraindications updated 2026-07-22 19:08 by etl_backfill • Backfilled from existing medication fields
- usage updated 2026-07-22 19:08 by etl_backfill • Backfilled from existing medication fields
- side_effects updated 2026-07-22 18:40 by etl_backfill • Backfilled from existing medication fields
- contraindications updated 2026-07-22 18:40 by etl_backfill • Backfilled from existing medication fields
- usage updated 2026-07-22 18:40 by etl_backfill • Backfilled from existing medication fields
- side_effects updated 2026-07-22 08:29 by etl_backfill • Backfilled from existing medication fields
- contraindications updated 2026-07-22 08:29 by etl_backfill • Backfilled from existing medication fields
- usage updated 2026-07-22 08:29 by etl_backfill • Backfilled from existing medication fields
- side_effects updated 2026-07-20 10:05 by etl_backfill • Backfilled from existing medication fields
- contraindications updated 2026-07-20 10:05 by etl_backfill • Backfilled from existing medication fields
- usage updated 2026-07-20 10:05 by etl_backfill • Backfilled from existing medication fields
- side_effects updated 2026-07-19 13:48 by etl_backfill • Backfilled from existing medication fields
- contraindications updated 2026-07-19 13:48 by etl_backfill • Backfilled from existing medication fields
- usage updated 2026-07-19 13:48 by etl_backfill • Backfilled from existing medication fields
- side_effects updated 2026-07-16 16:34 by etl_backfill • Backfilled from existing medication fields
- contraindications updated 2026-07-16 16:34 by etl_backfill • Backfilled from existing medication fields
- usage updated 2026-07-16 16:34 by etl_backfill • Backfilled from existing medication fields
- side_effects updated 2026-07-16 15:43 by etl_backfill • Backfilled from existing medication fields
- contraindications updated 2026-07-16 15:43 by etl_backfill • Backfilled from existing medication fields
FDA Products & Applications (Animal Drugs @ FDA)
Official sponsor/proprietary-name/application-status records linked by active ingredient.
| Product | Sponsor | Application | Status | Published |
|---|
Data source: FDA Animal Drugs @ FDA (public search export).
Usage
Used for neuropathic pain and as an adjunct for seizure control; also used for situational anxiety/sedation in some cases.
Contraindications
Use caution with kidney disease; dose adjustments may be needed.
Side Effects
Sedation, ataxia, mild GI upset.
Source: FDA openFDA • Reference
Top Reported Reactions (openFDA)
De-duplicated reaction terms grouped by body system from FDA openFDA reports (not verified; does not prove causation).
Effectiveness
Lack of efficacy (endoparasite) - tapeworm (2)
• Dog
Showing top 5 for Effectiveness.
Other
Thrombocytopenia (4)
• Dog
Elevated symmetrical dimethylarginine (4)
• Dog
Conjunctivitis (3)
• Dog
Urolithiasis (2)
• Dog
Unclassifiable adverse event (2)
• Dog
Show more (26)
Trembling (2)
• Dog
Skin lesion NOS (2)
• Dog
Respiratory tract infection NOS (2)
• Dog
Regurgitation (2)
• Dog
Reduced globulins (2)
• Dog
Pyoderma (2)
• Dog
Proprioception deficit (2)
• Dog
Knuckling (2)
• Dog
Hypophosphataemia (2)
• Dog
Hypokalaemia (2)
• Cat
Hepatomegaly (2)
• Cat
Fracture (2)
• Dog
Erythema (2)
• Dog
Elevated alanine aminotransferase (2)
• Cat
Decreased activity (2)
• Cat
Death (2)
• Cat
Confusion (2)
• Dog
Abnormal radiograph finding (1)
• Cat
Abnormal movement NOS (1)
• Dog
Abnormal menace reflex test (1)
• Cat
Abnormal histology NOS (1)
• Dog
Abnormal cytology (1)
• Dog
Abdominal pain (1)
• Dog
Abdominal effusion (1)
• Dog
Abdominal discomfort (1)
• Dog
Abdominal cavity disorder NOS (1)
• Dog
Showing top 5 for Other.
Data source: FDA openFDA Animal & Veterinary adverse event reports.
Adverse Event Case Summaries (openFDA)
These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.
Cat, Domestic Shorthair, Female, 11 year, 3.992 kilogram • Drug: MSK, Unassigned, Oral • Reactions: Facial pruritus, Medication error NOS • Outcome: Recovered/Normal
- Report ID: USA-USFDACVM-2026-US-014454
- Serious AE: No
- Treated For AE: No
- Sex: Female
- Age: 11.00 Year
- Weight: 3.992 Kilogram
- Case-reported brand: MSK
- Case-reported manufacturer: MSK
- Route: Oral
- Form: Unassigned
Reactions Reported:
Facial pruritus
Medication error NOS
Outcomes: Recovered/Normal
Dog, Retriever - Labrador, Male, 11 year, 47.174 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Partial lack of efficacy • Outcome: Ongoing
- Report ID: USA-USFDACVM-2026-US-014361
- Serious AE: Yes
- Treated For AE: Yes
- Sex: Male
- Age: 11.00 Year
- Weight: 47.174 Kilogram
- Case-reported brand: MSK
- Case-reported manufacturer: MSK
- Route: Unknown
- Form: Unassigned
Reactions Reported:
Partial lack of efficacy
Outcomes: Ongoing
Dog, Schnauzer - Miniature, Male, 5 year, 10.16 kilogram • Drug: MSK, Unassigned, Oral • Reactions: Lameness, Wobbliness, Tiredness (lethargy), Unable to walk, Weakness… • Outcome: Ongoing
- Report ID: USA-USFDACVM-2026-US-014449
- Serious AE: Yes
- Treated For AE: Yes
- Sex: Male
- Age: 5.00 Year
- Weight: 10.160 Kilogram
- Case-reported brand: MSK
- Case-reported manufacturer: MSK
- Route: Oral
- Form: Unassigned
Reactions Reported:
Lameness
Wobbliness
Tiredness (lethargy)
Unable to walk
Weakness
Fever
Immune-mediated polyarthritis
Gastritis
Abdominal cavity disorder NOS
Abnormal ultrasound finding
Hyperproteinaemia
Lymphopenia
Eosinopenia
Medication error NOS
Outcomes: Ongoing
Dog, Crossbred Canine/dog, Male, 10 year, 32.205 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Musculoskeletal disorder NOS, Aggression, Unable to walk, Urinary incontinence, Melaena… • Outcome: Euthanized
- Report ID: USA-USFDACVM-2026-US-014374
- Serious AE: Yes
- Treated For AE: Yes
- Sex: Male
- Age: 10.00 Year
- Weight: 32.205 Kilogram
- Case-reported brand: MSK
- Case-reported manufacturer: MSK
- Route: Unknown
- Form: Unassigned
Reactions Reported:
Musculoskeletal disorder NOS
Aggression
Unable to walk
Urinary incontinence
Melaena
Vomiting
Tiredness (lethargy)
Death by euthanasia
Neurological signs NOS
Outcomes: Euthanized
Dog, Retriever - Labrador, Unknown • Drug: MSK, Unknown • Reactions: Death • Outcome: Died
- Report ID: USA-USFDACVM-2026-US-014204
- Serious AE: Yes
- Treated For AE: No
- Sex: Unknown
- Case-reported brand: MSK
- Case-reported manufacturer: MSK
- Route: Unknown
Reactions Reported:
Death
Outcomes: Died
Cat, Domestic Shorthair, Female, 20 year, 2.631 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Agitation, Vocalisation, Unsteady walking (ataxia), Weakness • Outcome: Recovered/Normal
- Report ID: USA-USFDACVM-2026-US-014011
- Serious AE: Yes
- Treated For AE: Yes
- Sex: Female
- Age: 20.00 Year
- Weight: 2.631 Kilogram
- Case-reported brand: MSK
- Case-reported manufacturer: MSK
- Route: Unknown
- Form: Unassigned
Reactions Reported:
Agitation
Vocalisation
Unsteady walking (ataxia)
Weakness
Outcomes: Recovered/Normal
Dog, Retriever - Golden, Female, 4 year, 34.019 kilogram • Drug: MSK, Unassigned, Unknown, Dose: 300 Milligram per animal, Frequency: 12 per hour • Reactions: Lameness, Difficulty to rise, Joint swelling, Abnormal radiograph finding, Bone and joint disorder NOS… • Outcome: Ongoing
- Report ID: USA-USFDACVM-2026-US-014065
- Serious AE: Yes
- Treated For AE: Yes
- Sex: Female
- Age: 4.00 Year
- Weight: 34.019 Kilogram
- Case-reported brand: MSK
- Case-reported manufacturer: MSK
- Route: Unknown
- Form: Unassigned
- Dose: 300 Milligram per animal
- Frequency: 12 per hour
Reactions Reported:
Lameness
Difficulty to rise
Joint swelling
Abnormal radiograph finding
Bone and joint disorder NOS
Discomfort NOS
Outcomes: Ongoing
Dog, Shepherd Dog - German, Female, 9 year, 35.698 kilogram • Drug: MSK, Unassigned, Oral, Dose: 200 Milligram per animal, Frequency: 12 per hour • Reactions: Joint pain, Lameness, Depression, Difficulty standing, Decreased appetite… • Outcome: Outcome Unknown
- Report ID: USA-USFDACVM-2026-US-014048
- Serious AE: Yes
- Treated For AE: Yes
- Sex: Female
- Age: 9.00 Year
- Weight: 35.698 Kilogram
- Case-reported brand: MSK
- Case-reported manufacturer: MSK
- Route: Oral
- Form: Unassigned
- Dose: 200 Milligram per animal
- Frequency: 12 per hour
Reactions Reported:
Joint pain
Lameness
Depression
Difficulty standing
Decreased appetite
Abnormal radiograph finding
Bone and joint disorder NOS
Joint effusion
Spondylosis
Outcomes: Outcome Unknown
Data source: FDA openFDA Animal & Veterinary adverse event reports.
Overdose Information
Overdose can cause severe sedation, loss of coordination, muscle tremors, and respiratory depression. Emergency care: IV fluids, monitoring.
Storage & Handling
Store at room temperature.
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Medical Disclaimer: The medication details provided on Roxee are for informational purposes only and are not a substitute for professional veterinary advice. Always consult your veterinarian about your pet's specific needs.