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Roxee Meds Catalog

Glycosaminoglycan Polysulfate

Medication catalog facts with explicit FDA-approval, off-label, source-limited, and safety context.

Both Source review pending Source coverage pending Owner quick guide first
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Data freshness

Storefront facts
Source review pending
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Roxee is still reviewing source support for this medication profile.

FDA applications
Regulatory match pending
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Roxee has safety or ingredient evidence for this medication, but a regulatory product/application match is still pending.

Safety reports
Safety data refreshed
May 5, 2026, 10:01 a.m.

openFDA reaction terms and case summaries are supporting evidence, not proof of causality.

Source timing details
Source timing details
  • Storefront facts: Source Roxee | Refreshed May 5, 2026, 10:05 AM UTC
    The storefront fact projection used for browse cards and quick facts.
  • openFDA reaction terms: Source FDA openFDA | Refreshed May 5, 2026, 10:04 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed May 5, 2026, 10:04 AM UTC

Evidence

Reviewed / Updated / Sources

Reviewed by: Not available

Last reviewed: April 15, 2026

Updated: April 15, 2026, 10:04 AM UTC

Sources:
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Glycosaminoglycan Polysulfate

Glycosaminoglycan Polysulfate

Drug type: Generic ingredient • Generic profile • Source coverage pending

Both 80% storefront ready

Species: Both

Approval status: Source coverage pending. Roxee has limited supporting content for this record, but no on-page official FDA animal-drug document is linked yet. Treat it as source-limited until the ETL backfill adds official coverage.

Medication Snapshot

Merged from the current Roxee medication system with field-level provenance, freshness, and completeness tracking.

Glycosaminoglycan Polysulfate

Senvelgo (velagliflozin oral solution) is approved in cats for control of hyperglycemia associated with diabetes mellitus. Species commonly shown: Both.

Generic name
Glycosaminoglycan Polysulfate
Species
Both
Completeness
80%
Validation
Incomplete

Indications / Uses

Senvelgo (velagliflozin oral solution) is approved in cats for control of hyperglycemia associated with diabetes mellitus.

Side Effects

Top reported reactions (openFDA): Low platelet count, Not eating, Vomiting.

FAQ

Both

Source Transparency

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Pet Owner Quick Guide

Start here first for the safest next-step summary before the deeper medication detail.

Roxee still has limited plain-language guidance for this medication. Use the official documents and your veterinarian's instructions for product-specific details.

Used for:

Your vet decides this. Here's what owners typically ask/watch for.

Dosing note:

Exact dosing depends on your pet's species, weight, and health status. Use your veterinarian's instructions for the exact dose and schedule.

What to watch for:

  • Vomiting (1 reports)
  • wobbly/unsteady walking (1 reports)
  • very low energy (1 reports)

When to call the vet:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
  • Facial swelling or hives.
  • Blood in vomit or stool.

What to tell or ask your vet today:

  • Is this medicine the right fit for my pet’s current symptoms?
  • Which warning signs mean I should call back right away?
  • How should I handle missed doses or refusal to take the medicine?
Major cautions & emergency warning signs

Side effects to monitor:

  • Vomiting
  • wobbly/unsteady walking
  • very low energy

Most reported reactions:

  • Vomiting (1 reports)
  • Unsteady walking (ataxia) (1 reports)
  • Tiredness (lethargy) (1 reports)

Emergency warning signs:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
Talk to a Vet / Find a Vet Near You Start Symptom Intake

Quick Facts

Official label facts first, then secondary summaries. Marketing content is separated below.

Species: Both
Manufacturer: Manufacturer not confirmed

Adverse Reactions

Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.

Tap or hover a reaction to see what it means in plain language.

Tracked signals
32
Reported cases
32
Serious reports
30
Species represented
2
Grouped by Body System
Digestive (4) · Vomiting, Loss of appetite, Diarrhea Skin & allergy (1) · Joint swelling Neurologic (4) · Unsteady walking (ataxia), Tiredness (lethargy), Head tilt - neurological disorder Behavior (1) · Anxiety Other (22) · Loose bowel, Limb non-weight bearing, Joint effusion
Most Reported Reactions
Reaction Body system Cases Species Serious cases
Digestive 1 Dog 1
Neurologic 1 Dog 1
Neurologic 1 Dog 1
Digestive 1 Dog 1
Other 1 Dog 1
Other 1 Dog 1
Skin & allergy 1 Cat 1
Other 1 Dog 1

Species coverage: Dog (27) Cat (5)

View detailed reaction table
Reaction Body system Species Seriousness Frequency Reports
Digestive Dog Serious - 1
Neurologic Dog Serious - 1
Neurologic Dog Serious - 1
Digestive Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Skin & allergy Cat Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Non-serious - 1
Other Dog Serious - 1
Neurologic Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Non-serious - 1
Other Dog Serious - 1
Digestive Cat Serious - 1
Neurologic Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Digestive Cat Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Behavior Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Source metadata:
Veterinary reference (advanced)

Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.

At a Glance

Quick facts and links to official labeling and safety signals.

Data freshness
  • Storefront facts: Source Roxee | Refreshed May 5, 2026, 10:05 AM UTC
    The storefront fact projection used for browse cards and quick facts.
  • openFDA reaction terms: Source FDA openFDA | Refreshed May 5, 2026, 10:04 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed May 5, 2026, 10:04 AM UTC
Official (FDA)
Identity: Generic ingredient • No FDA branded products linked
No official FDA brand rows linked yet for this ingredient.
Case-reported brands (openFDA): MSK
Catalog species: Both
Safety (openFDA)
Top reactions: Dog 66 • Cat 9 • View
Case summaries: 14 (showing 8) • View
openFDA reports are unverified and do not prove causation.
Diagnosis Codes

Diagnosis-code mappings are not available for this medication yet.

Counseling and Monitoring Highlights

Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.

Top reaction signals
Vomiting (1) Unsteady walking (ataxia) (1) Tiredness (lethargy) (1) Loss of appetite (1) Loose bowel (1) Limb non-weight bearing (1) Joint swelling (1) Joint effusion (1)

Data Sources & Change Log

Every non-trivial field is expected to include provenance and update timestamps.

Official 19 Clinical 8 Manufacturer 0 Marketing 0
Current Field Facts
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-21)
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-20)
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-19)
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-17)
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-16)
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-16)
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-15)
  • side_effects: Top reported reactions (openFDA): Low platelet count, Not eating, Vomiting. (Clinical, 2026-04-11)
  • side_effects: Top reported reactions (openFDA): Low platelet count, Not eating, Vomiting. (Official, 2026-05-05)
  • side_effects: Top reported reactions (openFDA): Low platelet count, Not eating, Vomiting. (Official, 2026-05-03)
  • side_effects: Top reported reactions (openFDA): Low platelet count, Not eating, Vomiting. (Official, 2026-04-30)
  • side_effects: Top reported reactions (openFDA): Low platelet count, Not eating, Vomiting. (Official, 2026-04-29)
  • side_effects: Top reported reactions (openFDA): Low platelet count, Not eating, Vomiting. (Official, 2026-04-28)
  • side_effects: Top reported reactions (openFDA): Low platelet count, Not eating, Vomiting. (Official, 2026-04-27)
  • side_effects: Top reported reactions (openFDA): Low platelet count, Not eating, Vomiting. (Official, 2026-04-26)
  • side_effects: Top reported reactions (openFDA): Low platelet count, Not eating, Vomiting. (Official, 2026-04-25)
  • side_effects: Top reported reactions (openFDA): Low platelet count, Not eating, Vomiting. (Official, 2026-04-17)
  • side_effects: Top reported reactions (openFDA): Low platelet count, Not eating, Vomiting. (Official, 2026-04-15)
  • side_effects: Top reported reactions (openFDA): Low platelet count, Not eating, Vomiting. (Official, 2026-04-15)
  • side_effects: Top reported reactions (openFDA): Low platelet count, Not eating, Vomiting. (Official, 2026-04-07)
Recent Revisions
  • side_effects updated 2026-05-05 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-05-03 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-04-30 10:09 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-04-29 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-04-28 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-04-27 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-04-26 10:06 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-04-25 10:05 by etl_backfill • Backfilled from existing medication fields
  • monitoring updated 2026-04-21 10:07 by curated_loader • Clinical monitoring context for feline diabetes management.
  • usage updated 2026-04-21 10:07 by curated_loader • Usage statement from FDA warning letter and approved-product context.
  • drug_profile_type updated 2026-04-21 10:07 by curated_loader • FDA source confirms Senvelgo as a branded approved product.
  • manufacturer_name updated 2026-04-21 10:07 by curated_loader • FDA warning letter identifies the approved sponsor/manufacturer.
  • brand_names updated 2026-04-21 10:07 by curated_loader • FDA warning letter references Senvelgo as the approved animal drug.
  • approval_reference updated 2026-04-21 10:07 by curated_loader • Official FDA application reference for Senvelgo.
  • monitoring updated 2026-04-20 10:08 by curated_loader • Clinical monitoring context for feline diabetes management.
  • usage updated 2026-04-20 10:08 by curated_loader • Usage statement from FDA warning letter and approved-product context.
  • drug_profile_type updated 2026-04-20 10:08 by curated_loader • FDA source confirms Senvelgo as a branded approved product.
  • manufacturer_name updated 2026-04-20 10:08 by curated_loader • FDA warning letter identifies the approved sponsor/manufacturer.
  • brand_names updated 2026-04-20 10:08 by curated_loader • FDA warning letter references Senvelgo as the approved animal drug.
  • approval_reference updated 2026-04-20 10:08 by curated_loader • Official FDA application reference for Senvelgo.

Top Reported Reactions (openFDA)

De-duplicated reaction terms grouped by body system from FDA openFDA reports (not verified; does not prove causation).

Digestive
Vomiting (1) • Dog Loss of appetite (1) • Dog Diarrhea (1) • Cat Decreased appetite (1) • Cat

Showing top 5 for Digestive.

Skin & allergy
Joint swelling (1) • Cat

Showing top 5 for Skin & allergy.

Neurologic
Unsteady walking (1) • Dog Tiredness (1) • Dog Head tilt - neurological disorder (1) • Dog Depression (1) • Dog

Showing top 5 for Neurologic.

Behavior
Anxiety (1) • Dog

Showing top 5 for Behavior.

Other
Loose bowel (1) • Dog Limb non-weight bearing (1) • Dog Joint effusion (1) • Dog Injection site pain (1) • Dog Inappetence (1) • Dog
Show more (17)
Horizontal nystagmus (1) • Dog Generalised weakness (1) • Dog Excessive chewing, licking and/or grooming (1) • Dog Elevated gamma-glutamyl transferase (1) • Dog Elevated blood urea nitrogen (1) • Dog Discomfort NOS (1) • Dog Dehydration (1) • Dog Decreased body temperature (1) • Dog Death by euthanasia (1) • Dog Death (1) • Dog Congestion of mucous membrane (1) • Dog Collapse NOS (1) • Dog Chewing disorder (1) • Dog Bone and joint disorder NOS (1) • Cat Anaphylaxis (1) • Dog Abnormal tail posture (1) • Dog Abnormal radiograph finding (1) • Cat

Showing top 5 for Other.

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Adverse Event Case Summaries (openFDA)

These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.

Dog, Shepherd Dog - German, Female, 11 year, 20.865 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Vomiting, Not eating, Tiredness (lethargy), Reluctant to move, Seizure NOS • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-075421
  • Serious AE: Yes
  • Treated For AE: No
  • Sex: Female
  • Age: 11.00 Year
  • Weight: 20.865 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Unassigned
Reactions Reported:
Vomiting Not eating Tiredness (lethargy) Reluctant to move Seizure NOS
Outcomes: Ongoing

Dog, ['Retriever - Golden', 'Beagle', 'Chow Chow'], Male, 11 year, 19.504 kilogram • Drug: MSK, Unassigned, Subcutaneous, Frequency: 14 per day • Reactions: Unsteady walking (ataxia), Vestibular disorder NOS, Weight loss, Head tilt - neurological disorder, Low vision… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-075189
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 11.00 Year
  • Weight: 19.504 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Subcutaneous
  • Form: Unassigned
  • Frequency: 14 per day
Reactions Reported:
Unsteady walking (ataxia) Vestibular disorder NOS Weight loss Head tilt - neurological disorder Low vision Urinary incontinence Unable to rise Urinary tract infection Polydipsia Horizontal nystagmus Generalised weakness Depression
Outcomes: Ongoing

Dog, Terrier - Irish Soft-coated Wheaten, Male, 12 year, 21.319 kilogram • Drug: MSK, Solution, Intramuscular, Dose: 0.90 mL per dose • Reactions: Death • Outcome: Died

  • Report ID: USA-USFDACVM-2025-US-074219
  • Serious AE: Yes
  • Treated For AE: No
  • Sex: Male
  • Age: 12.00 Year
  • Weight: 21.319 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Intramuscular
  • Form: Solution
  • Dose: 0.90 mL per dose
Reactions Reported:
Death
Outcomes: Died

Dog, Retriever - Chesapeake Bay, Female, 4 year, 35.743 kilogram • Drug: MSK, Solution, Intramuscular, Dose: 1.57 mL per dose • Reactions: Vomiting, Loss of appetite, Loose stool, Neutrophilia, Dehydration… • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-074217
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 4.00 Year
  • Weight: 35.743 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Intramuscular
  • Form: Solution
  • Dose: 1.57 mL per dose
Reactions Reported:
Vomiting Loss of appetite Loose stool Neutrophilia Dehydration Low platelet count
Outcomes: Outcome Unknown

Dog, Retriever - Labrador, Male, 5 year, 39.463 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Limb non-weight bearing, Bone and joint disorder NOS, Other abnormal test result NOS, Abnormal radiograph finding, Urinary tract obstruction/blockage… • Outcome: Euthanized

  • Report ID: USA-USFDACVM-2025-US-074601
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 5.00 Year
  • Weight: 39.463 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Unassigned
Reactions Reported:
Limb non-weight bearing Bone and joint disorder NOS Other abnormal test result NOS Abnormal radiograph finding Urinary tract obstruction/blockage Discomfort NOS Walking difficulty Death by euthanasia Osteochondritis dissecans Urolithiasis
Outcomes: Euthanized

Dog, Retriever - Labrador, Male, 11 year, 37.83 kilogram • Drug: MSK, Solution, Intramuscular, Dose: 1.60 mL per dose • Reactions: Anaphylaxis, Seizure NOS, Vomiting, Collapse NOS, Loose bowel… • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2025-US-073464
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 11.00 Year
  • Weight: 37.830 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Intramuscular
  • Form: Solution
  • Dose: 1.60 mL per dose
Reactions Reported:
Anaphylaxis Seizure NOS Vomiting Collapse NOS Loose bowel Congestion of mucous membrane Low blood pressure Decreased body temperature
Outcomes: Recovered/Normal

Dog, ['Pit Bull', 'Dog (unknown)'], Female, 11.5 year, 37.376 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Joint swelling, Bone and joint disorder NOS, Sarcoma NOS • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-074653
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 11.50 Year
  • Weight: 37.376 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Unassigned
Reactions Reported:
Joint swelling Bone and joint disorder NOS Sarcoma NOS
Outcomes: Ongoing

Dog, Shepherd Dog - Australian, Male, 12.92 year, 11.79 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Tiredness (lethargy), Inappetence, Elevated blood urea nitrogen, Vomiting • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-074767
  • Serious AE: No
  • Treated For AE: Yes
  • Sex: Male
  • Age: 12.92 Year
  • Weight: 11.790 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Unassigned
Reactions Reported:
Tiredness (lethargy) Inappetence Elevated blood urea nitrogen Vomiting
Outcomes: Ongoing

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Overdose Information

No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.

Storage & Handling

No approved storage guidance is linked yet for this ingredient. Use manufacturer packaging and veterinary guidance for handling/storage.

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