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Roxee Meds Catalog

Hydromorphone

Medication catalog facts with explicit FDA-approval, off-label, source-limited, and safety context.

Both Source review pending Source coverage pending Owner quick guide first
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Data freshness

Storefront facts
Source review pending
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Roxee is still reviewing source support for this medication profile.

FDA applications
Regulatory match pending
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Roxee has safety or ingredient evidence for this medication, but a regulatory product/application match is still pending.

Safety reports
Safety data refreshed
May 5, 2026, 10:01 a.m.

openFDA reaction terms and case summaries are supporting evidence, not proof of causality.

Source timing details
Source timing details
  • Storefront facts: Source Roxee | Refreshed May 5, 2026, 10:05 AM UTC
    The storefront fact projection used for browse cards and quick facts.
  • openFDA reaction terms: Source FDA openFDA | Refreshed May 5, 2026, 10:04 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed May 5, 2026, 10:04 AM UTC

Evidence

Reviewed / Updated / Sources

Reviewed by: Not available

Last reviewed: April 15, 2026

Updated: April 15, 2026, 10:04 AM UTC

Sources:
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Hydromorphone

Hydromorphone

Drug type: Generic ingredient • Generic profile • Source coverage pending

Both 80% storefront ready

Species: Both

Approval status: Source coverage pending. Roxee has limited supporting content for this record, but no on-page official FDA animal-drug document is linked yet. Treat it as source-limited until the ETL backfill adds official coverage.

Medication Snapshot

Merged from the current Roxee medication system with field-level provenance, freshness, and completeness tracking.

Hydromorphone

Senvelgo (velagliflozin oral solution) is approved in cats for control of hyperglycemia associated with diabetes mellitus. Species commonly shown: Both.

Generic name
Hydromorphone
Species
Both
Completeness
80%
Validation
Incomplete

Indications / Uses

Senvelgo (velagliflozin oral solution) is approved in cats for control of hyperglycemia associated with diabetes mellitus.

Side Effects

Top reported reactions (openFDA): Vomiting, Death, Injection site swelling, Not eating, Lack of efficacy - NOS, Tachycardia.

FAQ

Both

Source Transparency

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Pet Owner Quick Guide

Start here first for the safest next-step summary before the deeper medication detail.

Roxee still has limited plain-language guidance for this medication. Use the official documents and your veterinarian's instructions for product-specific details.

Used for:

Your vet decides this. Here's what owners typically ask/watch for.

Dosing note:

Exact dosing depends on your pet's species, weight, and health status. Use your veterinarian's instructions for the exact dose and schedule.

What to watch for:

  • wobbly/unsteady walking (1 reports)
  • Loss of appetite (1 reports)
  • Elevated renal parameters (1 reports)

When to call the vet:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
  • Facial swelling or hives.
  • Blood in vomit or stool.

What to tell or ask your vet today:

  • Is this medicine the right fit for my pet’s current symptoms?
  • Which warning signs mean I should call back right away?
  • How should I handle missed doses or refusal to take the medicine?
Major cautions & emergency warning signs

Side effects to monitor:

  • wobbly/unsteady walking
  • Loss of appetite
  • Elevated renal parameters

Most reported reactions:

  • Unsteady walking (ataxia) (1 reports)
  • Loss of appetite (1 reports)
  • Elevated renal parameters (1 reports)

Emergency warning signs:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
Talk to a Vet / Find a Vet Near You Start Symptom Intake

Quick Facts

Official label facts first, then secondary summaries. Marketing content is separated below.

Species: Both
Manufacturer: Manufacturer not confirmed

Adverse Reactions

Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.

Tap or hover a reaction to see what it means in plain language.

Tracked signals
32
Reported cases
32
Serious reports
26
Species represented
2
Grouped by Body System
Digestive (3) · Loss of appetite, Drooling, Decreased appetite Skin & allergy (1) · Hair loss at application site Neurologic (2) · Unsteady walking (ataxia), Depression Behavior (2) · Biting -aggression, Behavioral disorder (unspecified) Other (24) · Elevated renal parameters, Dysphoria, Dull
Most Reported Reactions
Reaction Body system Cases Species Serious cases
Neurologic 1 Cat 1
Digestive 1 Dog 1
Other 1 Cat 1
Other 1 Cat 1
Other 1 Cat 1
Other 1 Cat 1
Other 1 Cat 1
Neurologic 1 Cat 1

Species coverage: Cat (22) Dog (10)

View detailed reaction table
Reaction Body system Species Seriousness Frequency Reports
Neurologic Cat Serious - 1
Digestive Dog Serious - 1
Skin & allergy Cat Non-serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Digestive Cat Non-serious - 1
Other Cat Serious - 1
Neurologic Cat Serious - 1
Other Cat Non-serious - 1
Other Dog Serious - 1
Other Cat Non-serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Digestive Dog Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Behavior Dog Serious - 1
Behavior Cat Serious - 1
Other Dog Non-serious - 1
Other Cat Serious - 1
Other Cat Non-serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Source metadata:
Veterinary reference (advanced)

Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.

At a Glance

Quick facts and links to official labeling and safety signals.

Data freshness
  • Storefront facts: Source Roxee | Refreshed May 5, 2026, 10:05 AM UTC
    The storefront fact projection used for browse cards and quick facts.
  • openFDA reaction terms: Source FDA openFDA | Refreshed May 5, 2026, 10:04 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed May 5, 2026, 10:04 AM UTC
Official (FDA)
Identity: Generic ingredient • No FDA branded products linked
No official FDA brand rows linked yet for this ingredient.
Case-reported brands (openFDA): MSK
Catalog species: Both
Safety (openFDA)
Top reactions: Dog 31 • Cat 21 • View
Case summaries: 11 (showing 8) • View
openFDA reports are unverified and do not prove causation.
Diagnosis Codes

Diagnosis-code mappings are not available for this medication yet.

Counseling and Monitoring Highlights

Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.

Top reaction signals
Unsteady walking (ataxia) (1) Loss of appetite (1) Elevated renal parameters (1) Dysphoria (1) Dull (1) Dry mucous membrane (1) Dilated pupils (1) Depression (1)

Data Sources & Change Log

Every non-trivial field is expected to include provenance and update timestamps.

Official 15 Clinical 5 Manufacturer 0 Marketing 0
Current Field Facts
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-21)
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-20)
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-19)
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-16)
  • side_effects: Top reported reactions (openFDA): Vomiting, Death, Injection site swelling, Not eating, Lack of efficacy - NOS, Tachycardia. (Clinical, 2026-04-11)
  • side_effects: Top reported reactions (openFDA): Vomiting, Death, Injection site swelling, Not eating, Lack of efficacy - NOS, Tachycardia. (Official, 2026-05-05)
  • side_effects: Top reported reactions (openFDA): Vomiting, Death, Injection site swelling, Not eating, Lack of efficacy - NOS, Tachycardia. (Official, 2026-05-03)
  • side_effects: Top reported reactions (openFDA): Vomiting, Death, Injection site swelling, Not eating, Lack of efficacy - NOS, Tachycardia. (Official, 2026-04-30)
  • side_effects: Top reported reactions (openFDA): Vomiting, Death, Injection site swelling, Not eating, Lack of efficacy - NOS, Tachycardia. (Official, 2026-04-29)
  • side_effects: Top reported reactions (openFDA): Vomiting, Death, Injection site swelling, Not eating, Lack of efficacy - NOS, Tachycardia. (Official, 2026-04-28)
  • side_effects: Top reported reactions (openFDA): Vomiting, Death, Injection site swelling, Not eating, Lack of efficacy - NOS, Tachycardia. (Official, 2026-04-27)
  • side_effects: Top reported reactions (openFDA): Vomiting, Death, Injection site swelling, Not eating, Lack of efficacy - NOS, Tachycardia. (Official, 2026-04-26)
  • side_effects: Top reported reactions (openFDA): Vomiting, Death, Injection site swelling, Not eating, Lack of efficacy - NOS, Tachycardia. (Official, 2026-04-25)
  • side_effects: Top reported reactions (openFDA): Vomiting, Death, Injection site swelling, Not eating, Lack of efficacy - NOS, Tachycardia. (Official, 2026-04-17)
  • side_effects: Top reported reactions (openFDA): Vomiting, Death, Injection site swelling, Not eating, Lack of efficacy - NOS, Tachycardia. (Official, 2026-04-15)
  • side_effects: Top reported reactions (openFDA): Vomiting, Death, Injection site swelling, Not eating, Lack of efficacy - NOS, Tachycardia. (Official, 2026-02-12)
  • usage: Senvelgo (velagliflozin oral solution) is approved in cats for control of hyperglycemia associated with diabetes mellitus. (Official, 2026-04-21)
  • usage: Senvelgo (velagliflozin oral solution) is approved in cats for control of hyperglycemia associated with diabetes mellitus. (Official, 2026-04-20)
  • usage: Senvelgo (velagliflozin oral solution) is approved in cats for control of hyperglycemia associated with diabetes mellitus. (Official, 2026-04-19)
  • usage: Senvelgo (velagliflozin oral solution) is approved in cats for control of hyperglycemia associated with diabetes mellitus. (Official, 2026-04-16)
Recent Revisions
  • side_effects updated 2026-05-05 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-05-03 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-04-30 10:09 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-04-29 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-04-28 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-04-27 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-04-26 10:06 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-04-25 10:05 by etl_backfill • Backfilled from existing medication fields
  • monitoring updated 2026-04-21 10:07 by curated_loader • Clinical monitoring context for feline diabetes management.
  • usage updated 2026-04-21 10:07 by curated_loader • Usage statement from FDA warning letter and approved-product context.
  • drug_profile_type updated 2026-04-21 10:07 by curated_loader • FDA source confirms Senvelgo as a branded approved product.
  • manufacturer_name updated 2026-04-21 10:07 by curated_loader • FDA warning letter identifies the approved sponsor/manufacturer.
  • brand_names updated 2026-04-21 10:07 by curated_loader • FDA warning letter references Senvelgo as the approved animal drug.
  • approval_reference updated 2026-04-21 10:07 by curated_loader • Official FDA application reference for Senvelgo.
  • monitoring updated 2026-04-20 10:09 by curated_loader • Clinical monitoring context for feline diabetes management.
  • usage updated 2026-04-20 10:09 by curated_loader • Usage statement from FDA warning letter and approved-product context.
  • drug_profile_type updated 2026-04-20 10:09 by curated_loader • FDA source confirms Senvelgo as a branded approved product.
  • manufacturer_name updated 2026-04-20 10:09 by curated_loader • FDA warning letter identifies the approved sponsor/manufacturer.
  • brand_names updated 2026-04-20 10:09 by curated_loader • FDA warning letter references Senvelgo as the approved animal drug.
  • approval_reference updated 2026-04-20 10:09 by curated_loader • Official FDA application reference for Senvelgo.

Top Reported Reactions (openFDA)

De-duplicated reaction terms grouped by body system from FDA openFDA reports (not verified; does not prove causation).

Digestive
Loss of appetite (1) • Dog Drooling (1) • Cat Decreased appetite (1) • Dog

Showing top 5 for Digestive.

Skin & allergy
Hair loss at application site (1) • Cat

Showing top 5 for Skin & allergy.

Neurologic
Unsteady walking (1) • Cat Depression (1) • Cat

Showing top 5 for Neurologic.

Behavior
Biting -aggression (1) • Dog Behavioral disorder (1) • Cat

Showing top 5 for Behavior.

Other
Elevated renal parameters (1) • Cat Dysphoria (1) • Cat Dull (1) • Cat Dry mucous membrane (1) • Cat Dilated pupils (1) • Cat
Show more (19)
Dehydration (1) • Cat Dehiscence (1) • Dog Defect Unknown/Not Specified (1) • Cat Decreased haematocrit (1) • Dog Decreased drinking (1) • Dog Death (1) • Cat Crying (1) • Cat Crust (1) • Dog Constipation (1) • Cat Conjunctivitis (1) • Dog Cardiomyopathy (1) • Cat Brain disorder NOS (1) • Cat Bradycardia (1) • Dog Bladder distension (1) • Cat Application site scar (1) • Dog Agonal breathing (1) • Cat Agitation (1) • Cat Adipsia (1) • Cat Abnormal menace reflex test (1) • Cat

Showing top 5 for Other.

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Adverse Event Case Summaries (openFDA)

These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.

Dog, Siberian Husky, Male, 9 year, 21.682 kilogram • Drug: MSK, Unassigned, Intramuscular • Reactions: Injection site lesion, Crust, Injection site ulcer, Injection site erythema, Injection site discharge NOS • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-075214
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 9.00 Year
  • Weight: 21.682 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Intramuscular
  • Form: Unassigned
Reactions Reported:
Injection site lesion Crust Injection site ulcer Injection site erythema Injection site discharge NOS
Outcomes: Ongoing

Cat, Persian, Male, 10.83 year, 4.67 kilogram • Drug: MSK, Unknown • Reactions: Hair loss at application site, Defect Unknown/Not Specified • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-074803
  • Serious AE: No
  • Treated For AE: No
  • Sex: Male
  • Age: 10.83 Year
  • Weight: 4.670 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Hair loss at application site Defect Unknown/Not Specified
Outcomes: Ongoing

Cat, Domestic Shorthair, Male, 3 year, 4.3 kilogram • Drug: MSK, Unknown • Reactions: Tiredness (lethargy), Dull, Behavioral disorder (unspecified), Shallow breathing, Death • Outcome: Died

  • Report ID: USA-USFDACVM-2025-US-073864
  • Serious AE: Yes
  • Treated For AE: No
  • Sex: Male
  • Age: 3.00 Year
  • Weight: 4.300 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Tiredness (lethargy) Dull Behavioral disorder (unspecified) Shallow breathing Death
Outcomes: Died

Cat, Domestic Shorthair, Male, 12 month, 4.354 kilogram • Drug: MSK • Reactions: Local swelling, Death • Outcome: Died

  • Report ID: USA-USFDACVM-2025-US-074903
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 12.00 Month
  • Weight: 4.354 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
Reactions Reported:
Local swelling Death
Outcomes: Died

Dog, ['Pointing Dog - Hungarian Short-haired (Vizsla)', 'Retriever - Labrador'], Male, 8 year, 40.415 kilogram • Drug: MSK, Injection, Intramuscular, Dose: 1.60 mL per dose, Frequency: 1 per day • Reactions: Application site scar, Injection site alopecia, Injection site reaction NOS, Injection site nodule, Mast cell tumour… • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-073513
  • Serious AE: No
  • Treated For AE: No
  • Sex: Male
  • Age: 8.00 Year
  • Weight: 40.415 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Intramuscular
  • Form: Injection
  • Dose: 1.60 mL per dose
  • Frequency: 1 per day
Reactions Reported:
Application site scar Injection site alopecia Injection site reaction NOS Injection site nodule Mast cell tumour Lack of efficacy
Outcomes: Outcome Unknown

Dog, ['Shepherd (unspecified)', 'Dog (unknown)'], Female, 11 month • Drug: MSK, Other • Reactions: Fracture, Thrombocytopenia, Respiratory tract infection NOS, Conjunctivitis, Unclassifiable adverse event… • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-073723
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 11.00 Month
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Other
Reactions Reported:
Fracture Thrombocytopenia Respiratory tract infection NOS Conjunctivitis Unclassifiable adverse event Other abnormal test result NOS Lack of efficacy (endoparasite) - tapeworm
Outcomes: Outcome Unknown

Dog, Portuguese Water Dog, Female, 6 year, 23.406 kilogram • Drug: MSK, Intramuscular • Reactions: Loss of appetite, Injection site itching, Swelling NOS, Tiredness (lethargy), Injection site mucopurulent discharge… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-071209
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 6.00 Year
  • Weight: 23.406 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Intramuscular
Reactions Reported:
Loss of appetite Injection site itching Swelling NOS Tiredness (lethargy) Injection site mucopurulent discharge Injection site swelling Injection site skin discolouration Injection site bruising Injection site abscess Injection site necrosis Sickness Injection site skin change NOS Other abnormal test result NOS
Outcomes: Ongoing

Dog, ['Mastiff (unspecified)', 'Dog (unknown)'], Female, 3 year, 35.834 kilogram • Drug: MSK, Injection, solution, Unknown • Reactions: Urinary incontinence • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-069797
  • Serious AE: No
  • Treated For AE: No
  • Sex: Female
  • Age: 3.00 Year
  • Weight: 35.834 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Injection, solution
Reactions Reported:
Urinary incontinence
Outcomes: Ongoing

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Overdose Information

No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.

Storage & Handling

No approved storage guidance is linked yet for this ingredient. Use manufacturer packaging and veterinary guidance for handling/storage.

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