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Roxee Meds Catalog

Ivermectin 272Mcg, Pyrantel 227Mg

Medication catalog facts with explicit FDA-approval, off-label, source-limited, and safety context.

Both Source review pending Source coverage pending Owner quick guide first
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Data freshness

Storefront facts
Source review pending
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Roxee is still reviewing source support for this medication profile.

FDA applications
Regulatory match pending
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Roxee has safety or ingredient evidence for this medication, but a regulatory product/application match is still pending.

Safety reports
Safety data refreshed
May 5, 2026, 10:01 a.m.

openFDA reaction terms and case summaries are supporting evidence, not proof of causality.

Source timing details
Source timing details
  • Storefront facts: Source Roxee | Refreshed May 5, 2026, 10:05 AM UTC
    The storefront fact projection used for browse cards and quick facts.
  • openFDA reaction terms: Source FDA openFDA | Refreshed May 5, 2026, 10:04 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed May 5, 2026, 10:04 AM UTC

Evidence

Reviewed / Updated / Sources

Reviewed by: Not available

Last reviewed: April 15, 2026

Updated: April 15, 2026, 10:04 AM UTC

Sources:
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Ivermectin 272Mcg, Pyrantel 227Mg

Ivermectin 272Mcg, Pyrantel 227Mg

Drug type: Generic ingredient • Generic profile • Source coverage pending

Both 80% storefront ready

Species: Both

Approval status: Source coverage pending. Roxee has limited supporting content for this record, but no on-page official FDA animal-drug document is linked yet. Treat it as source-limited until the ETL backfill adds official coverage.

Medication Snapshot

Merged from the current Roxee medication system with field-level provenance, freshness, and completeness tracking.

Ivermectin 272Mcg, Pyrantel 227Mg

Senvelgo (velagliflozin oral solution) is approved in cats for control of hyperglycemia associated with diabetes mellitus. Species commonly shown: Both.

Generic name
Ivermectin 272Mcg, Pyrantel 227Mg
Species
Both
Completeness
80%
Validation
Incomplete

Indications / Uses

Senvelgo (velagliflozin oral solution) is approved in cats for control of hyperglycemia associated with diabetes mellitus.

Side Effects

Top reported reactions (openFDA): INEFFECTIVE, HEARTWORM LARVAE, Vomiting, Lethargy (see also Central nervous system depression in 'Neurological'), Drug dose administration interval too long, Drug dose omission, Lack of efficacy (endoparasite) - hookworm.

FAQ

Both

Source Transparency

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Pet Owner Quick Guide

Start here first for the safest next-step summary before the deeper medication detail.

Roxee still has limited plain-language guidance for this medication. Use the official documents and your veterinarian's instructions for product-specific details.

Used for:

Your vet decides this. Here's what owners typically ask/watch for.

Dosing note:

Exact dosing depends on your pet's species, weight, and health status. Use your veterinarian's instructions for the exact dose and schedule.

What to watch for:

  • trouble breathing (1 reports)
  • Elevated serum alkaline phosphatase (1 reports)
  • Elevated globulins (1 reports)

When to call the vet:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Facial swelling or hives.
  • Blood in vomit or stool.

What to tell or ask your vet today:

  • Is this medicine the right fit for my pet’s current symptoms?
  • Which warning signs mean I should call back right away?
  • How should I handle missed doses or refusal to take the medicine?
Major cautions & emergency warning signs

Side effects to monitor:

  • trouble breathing
  • Elevated serum alkaline phosphatase
  • Elevated globulins

Most reported reactions:

  • Trouble breathing (dyspnea) (1 reports)
  • Elevated serum alkaline phosphatase (1 reports)
  • Elevated globulins (1 reports)

Emergency warning signs:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Facial swelling or hives.
Talk to a Vet / Find a Vet Near You Start Symptom Intake

Quick Facts

Official label facts first, then secondary summaries. Marketing content is separated below.

Species: Both
Manufacturer: Manufacturer not confirmed

Adverse Reactions

Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.

Tap or hover a reaction to see what it means in plain language.

Tracked signals
32
Reported cases
32
Serious reports
26
Species represented
2
Grouped by Body System
Digestive (3) · Loss of appetite, Drooling, Diarrhea Skin & allergy (1) · Alopecia NOS Behavior (1) · Behavioral disorder (unspecified) Other (27) · Trouble breathing (dyspnea), Elevated serum alkaline phosphatase, Elevated globulins
Most Reported Reactions
Reaction Body system Cases Species Serious cases
Other 1 Dog 1
Other 1 Dog 1
Other 1 Cat 1
Other 1 Dog 1
Other 1 Cat 1
Other 1 Dog 1
Other 1 Dog 1
Other 1 Dog 1

Species coverage: Dog (21) Cat (11)

View detailed reaction table
Reaction Body system Species Seriousness Frequency Reports
Other Dog Serious - 1
Digestive Dog Non-serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Non-serious - 1
Digestive Dog Non-serious - 1
Digestive Dog Non-serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Dog Non-serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Behavior Dog Non-serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Skin & allergy Dog Serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Source metadata:
Veterinary reference (advanced)

Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.

At a Glance

Quick facts and links to official labeling and safety signals.

Data freshness
  • Storefront facts: Source Roxee | Refreshed May 5, 2026, 10:05 AM UTC
    The storefront fact projection used for browse cards and quick facts.
  • openFDA reaction terms: Source FDA openFDA | Refreshed May 5, 2026, 10:04 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed May 5, 2026, 10:04 AM UTC
Official (FDA)
Identity: Generic ingredient • No FDA branded products linked
No official FDA brand rows linked yet for this ingredient.
Case-reported brands (openFDA): MSK
Catalog species: Both
Safety (openFDA)
Top reactions: Dog 18 • Cat 0 • View
Case summaries: 12 (showing 8) • View
openFDA reports are unverified and do not prove causation.
Diagnosis Codes

Diagnosis-code mappings are not available for this medication yet.

Counseling and Monitoring Highlights

Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.

Top reaction signals
Trouble breathing (dyspnea) (1) Elevated serum alkaline phosphatase (1) Elevated globulins (1) Elevated gamma-glutamyl transferase (1) Elevated creatinine (1) Elevated cholesterol (1) Elevated alanine aminotransferase (1) Dermal plaque (1)

Data Sources & Change Log

Every non-trivial field is expected to include provenance and update timestamps.

Official 16 Clinical 6 Manufacturer 0 Marketing 0
Current Field Facts
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-21)
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-20)
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-19)
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-17)
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-16)
  • side_effects: Top reported reactions (openFDA): INEFFECTIVE, HEARTWORM LARVAE, Vomiting, Lethargy (see also Central nervous system depression in 'Neurological'), Drug dose a… (Clinical, 2026-04-11)
  • side_effects: Top reported reactions (openFDA): INEFFECTIVE, HEARTWORM LARVAE, Vomiting, Lethargy (see also Central nervous system depression in 'Neurological'), Drug dose a… (Official, 2026-05-05)
  • side_effects: Top reported reactions (openFDA): INEFFECTIVE, HEARTWORM LARVAE, Vomiting, Lethargy (see also Central nervous system depression in 'Neurological'), Drug dose a… (Official, 2026-05-03)
  • side_effects: Top reported reactions (openFDA): INEFFECTIVE, HEARTWORM LARVAE, Vomiting, Lethargy (see also Central nervous system depression in 'Neurological'), Drug dose a… (Official, 2026-04-30)
  • side_effects: Top reported reactions (openFDA): INEFFECTIVE, HEARTWORM LARVAE, Vomiting, Lethargy (see also Central nervous system depression in 'Neurological'), Drug dose a… (Official, 2026-04-29)
  • side_effects: Top reported reactions (openFDA): INEFFECTIVE, HEARTWORM LARVAE, Vomiting, Lethargy (see also Central nervous system depression in 'Neurological'), Drug dose a… (Official, 2026-04-28)
  • side_effects: Top reported reactions (openFDA): INEFFECTIVE, HEARTWORM LARVAE, Vomiting, Lethargy (see also Central nervous system depression in 'Neurological'), Drug dose a… (Official, 2026-04-27)
  • side_effects: Top reported reactions (openFDA): INEFFECTIVE, HEARTWORM LARVAE, Vomiting, Lethargy (see also Central nervous system depression in 'Neurological'), Drug dose a… (Official, 2026-04-26)
  • side_effects: Top reported reactions (openFDA): INEFFECTIVE, HEARTWORM LARVAE, Vomiting, Lethargy (see also Central nervous system depression in 'Neurological'), Drug dose a… (Official, 2026-04-25)
  • side_effects: Top reported reactions (openFDA): INEFFECTIVE, HEARTWORM LARVAE, Vomiting, Lethargy (see also Central nervous system depression in 'Neurological'), Drug dose a… (Official, 2026-04-17)
  • side_effects: Top reported reactions (openFDA): INEFFECTIVE, HEARTWORM LARVAE, Vomiting, Lethargy (see also Central nervous system depression in 'Neurological'), Drug dose a… (Official, 2026-04-15)
  • side_effects: Top reported reactions (openFDA): INEFFECTIVE, HEARTWORM LARVAE, Vomiting, Lethargy (see also Central nervous system depression in 'Neurological'), Drug dose a… (Official, 2026-02-12)
  • usage: Senvelgo (velagliflozin oral solution) is approved in cats for control of hyperglycemia associated with diabetes mellitus. (Official, 2026-04-21)
  • usage: Senvelgo (velagliflozin oral solution) is approved in cats for control of hyperglycemia associated with diabetes mellitus. (Official, 2026-04-20)
  • usage: Senvelgo (velagliflozin oral solution) is approved in cats for control of hyperglycemia associated with diabetes mellitus. (Official, 2026-04-19)
Recent Revisions
  • side_effects updated 2026-05-05 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-05-03 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-04-30 10:09 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-04-29 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-04-28 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-04-27 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-04-26 10:06 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-04-25 10:05 by etl_backfill • Backfilled from existing medication fields
  • monitoring updated 2026-04-21 10:07 by curated_loader • Clinical monitoring context for feline diabetes management.
  • usage updated 2026-04-21 10:07 by curated_loader • Usage statement from FDA warning letter and approved-product context.
  • drug_profile_type updated 2026-04-21 10:07 by curated_loader • FDA source confirms Senvelgo as a branded approved product.
  • manufacturer_name updated 2026-04-21 10:07 by curated_loader • FDA warning letter identifies the approved sponsor/manufacturer.
  • brand_names updated 2026-04-21 10:07 by curated_loader • FDA warning letter references Senvelgo as the approved animal drug.
  • approval_reference updated 2026-04-21 10:07 by curated_loader • Official FDA application reference for Senvelgo.
  • monitoring updated 2026-04-20 10:08 by curated_loader • Clinical monitoring context for feline diabetes management.
  • usage updated 2026-04-20 10:08 by curated_loader • Usage statement from FDA warning letter and approved-product context.
  • drug_profile_type updated 2026-04-20 10:08 by curated_loader • FDA source confirms Senvelgo as a branded approved product.
  • manufacturer_name updated 2026-04-20 10:08 by curated_loader • FDA warning letter identifies the approved sponsor/manufacturer.
  • brand_names updated 2026-04-20 10:08 by curated_loader • FDA warning letter references Senvelgo as the approved animal drug.
  • approval_reference updated 2026-04-20 10:08 by curated_loader • Official FDA application reference for Senvelgo.

Top Reported Reactions (openFDA)

De-duplicated reaction terms grouped by body system from FDA openFDA reports (not verified; does not prove causation).

Digestive
Loss of appetite (1) • Dog Drooling (1) • Dog Diarrhea (1) • Dog

Showing top 5 for Digestive.

Skin & allergy
Alopecia NOS (1) • Dog

Showing top 5 for Skin & allergy.

Behavior
Behavioral disorder (1) • Dog

Showing top 5 for Behavior.

Other
Trouble breathing (1) • Dog Elevated serum alkaline phosphatase (1) • Dog Elevated globulins (1) • Cat Elevated gamma-glutamyl transferase (1) • Dog Elevated creatinine (1) • Cat
Show more (22)
Elevated cholesterol (1) • Dog Elevated alanine aminotransferase (1) • Dog Drug dose administration interval too long (1) • Dog Dermal plaque (1) • Dog Dehydration (1) • Cat Decreased activity (1) • Cat Death (1) • Cat Crying (1) • Dog Crust (1) • Dog Crackles on auscultation (1) • Dog Cough (1) • Dog Conjunctivitis (1) • Dog Complication of diabetes (1) • Dog Cardiomyopathy (1) • Cat Cachexia (1) • Cat Bradycardia (1) • Cat Bacterial skin infection NOS (1) • Dog Angioedema (1) • Dog Abnormal ultrasound finding (1) • Dog Abnormal radiograph finding (1) • Cat Abnormal histology NOS (1) • Cat Abnormal cytology (1) • Cat

Showing top 5 for Other.

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Adverse Event Case Summaries (openFDA)

These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.

Dog, Dog (unknown), Male • Drug: MSK, Tablet, chewable, Unknown • Reactions: Sickness, Tiredness (lethargy), Loss of appetite, Staggering • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2025-US-075492
  • Serious AE: No
  • Treated For AE: No
  • Sex: Male
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Tablet, chewable
Reactions Reported:
Sickness Tiredness (lethargy) Loss of appetite Staggering
Outcomes: Recovered/Normal

Dog, Beagle, Female, 4 year, 9.979 kilogram • Drug: MSK, Tablet, chewable, Oral, Dose: 1 tablet per animal • Reactions: Lack of efficacy (endoparasite) - hookworm • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-074016
  • Serious AE: No
  • Treated For AE: Yes
  • Sex: Female
  • Age: 4.00 Year
  • Weight: 9.979 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet, chewable
  • Dose: 1 tablet per animal
Reactions Reported:
Lack of efficacy (endoparasite) - hookworm
Outcomes: Ongoing

Dog, Spaniel - King Charles Cavalier, Male, 5 year, 15.422 kilogram • Drug: MSK, Tablet, chewable, Oral, Dose: 1 tablet per animal, Frequency: 1 per month • Reactions: Lack of efficacy (bacteria) - Anaplasma • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-073999
  • Serious AE: No
  • Treated For AE: No
  • Sex: Male
  • Age: 5.00 Year
  • Weight: 15.422 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet, chewable
  • Dose: 1 tablet per animal
  • Frequency: 1 per month
Reactions Reported:
Lack of efficacy (bacteria) - Anaplasma
Outcomes: Outcome Unknown

Dog, Collie - Border, Male, 10 year, 19.051 kilogram • Drug: MSK, Tablet, chewable, Oral, Dose: 1 tablet per animal • Reactions: Lack of efficacy (endoparasite) - heartworm • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-074655
  • Serious AE: No
  • Treated For AE: Yes
  • Sex: Male
  • Age: 10.00 Year
  • Weight: 19.051 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet, chewable
  • Dose: 1 tablet per animal
Reactions Reported:
Lack of efficacy (endoparasite) - heartworm
Outcomes: Ongoing

Dog, Shepherd Dog - Belgian Malinois, Male, 2 year, 28.576 kilogram • Drug: MSK, Tablet, Oral, Dose: 1 tablet per animal, Frequency: 1 per month • Reactions: Lack of efficacy (bacteria) - Anaplasma • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-074299
  • Serious AE: No
  • Treated For AE: No
  • Sex: Male
  • Age: 2.00 Year
  • Weight: 28.576 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet
  • Dose: 1 tablet per animal
  • Frequency: 1 per month
Reactions Reported:
Lack of efficacy (bacteria) - Anaplasma
Outcomes: Ongoing

Dog, Shepherd Dog - German, Female, 4 year, 38.555 kilogram • Drug: MSK, Tablet, chewable, Oral, Dose: 1 tablet per animal, Frequency: 1 per month • Reactions: Behavioral disorder (unspecified), Reluctant to move, Pacing, Crying, Nasal discharge • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-075100
  • Serious AE: No
  • Treated For AE: No
  • Sex: Female
  • Age: 4.00 Year
  • Weight: 38.555 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet, chewable
  • Dose: 1 tablet per animal
  • Frequency: 1 per month
Reactions Reported:
Behavioral disorder (unspecified) Reluctant to move Pacing Crying Nasal discharge
Outcomes: Outcome Unknown

Dog, Havanese, Female, 8 year, 3.175 kilogram • Drug: MSK, Tablet, chewable, Oral, Dose: 1 tablet per animal • Reactions: Intestinal disorder NOS • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-075083
  • Serious AE: No
  • Treated For AE: Yes
  • Sex: Female
  • Age: 8.00 Year
  • Weight: 3.175 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet, chewable
  • Dose: 1 tablet per animal
Reactions Reported:
Intestinal disorder NOS
Outcomes: Outcome Unknown

Dog, Sheepdog (unspecified), Female, 8 year, 32.205 kilogram • Drug: MSK, Tablet, Oral, Dose: 272 Microgram per animal, Frequency: 1 per month • Reactions: Vomiting • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2025-US-073495
  • Serious AE: No
  • Treated For AE: No
  • Sex: Female
  • Age: 8.00 Year
  • Weight: 32.205 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet
  • Dose: 272 Microgram per animal
  • Frequency: 1 per month
Reactions Reported:
Vomiting
Outcomes: Recovered/Normal

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Overdose Information

No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.

Storage & Handling

No approved storage guidance is linked yet for this ingredient. Use manufacturer packaging and veterinary guidance for handling/storage.

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