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Roxee Medication Guide

Ivermectin 34Mcg, Pyrantel Pamoate 28.5Mg, Praziquantel 28.5Mg

Medication reference facts with explicit FDA-approval, off-label, source-limited, and safety context. Roxee does not sell, prescribe, or dispense medications.

Both Reference complete Regulatory linkage incomplete Rx required Chewable tablet Virbac AH, Inc Official label facts Owner quick guide first
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Data freshness

Reference facts
Reference refreshed
Jun 22, 2026, 10:47 a.m.

These are the reference facts Roxee uses on browse cards and quick facts.

FDA applications
No FDA application data linked
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Sponsor, product, and application records imported from Animal Drugs @ FDA.

Safety reports
No safety reports linked
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openFDA reaction terms and case summaries are supporting evidence, not proof of causality.

Source timing details
Source timing details
  • Reference facts: Source Roxee | Refreshed Jun 22, 2026, 10:47 AM UTC
    The reference fact projection used for browse cards and quick facts.
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Ivermectin 34Mcg, Pyrantel Pamoate 28.5Mg, Praziquantel 28.5Mg

Ivermectin 34Mcg, Pyrantel Pamoate 28.5Mg, Praziquantel 28.5Mg

Drug type: Generic ingredient • Branded profile • Regulatory linkage incomplete

Both Chewable tablet Rx required 100% reference complete

Species: Both

Approval status: Official document linked, regulatory match incomplete. An official source document is available, but Roxee has not linked this row to a confirmed FDA animal-drug application or product record yet.

Medication Snapshot

Merged from the current Roxee medication system with field-level provenance, freshness, and completeness tracking.

Ivermectin 34Mcg, Pyrantel Pamoate 28.5Mg, Praziquantel 28.5Mg

Iverhart Max Chew is approved for dogs to prevent canine heartworm disease for one month after infection and to treat and control labeled roundworm, hookworm, and tapeworm infections. Species commonly shown: Dogs.

Generic name
Ivermectin 34Mcg, Pyrantel Pamoate 28.5Mg, Praziquantel 28.5Mg
Brand names
Iverhart Max Chew
Medication class
branded
Manufacturer
Virbac AH, Inc
Species
Dog
Dosage forms
Chewable tablet
Strengths
34 mcg ivermectin / 28.5 mg pyrantel pamoate / 28.5 mg praziquantel
Prescription
Prescription required
Completeness
100%
Validation
Needs review
Brand names
Iverhart Max Chew
Dosage forms
Chewable tablet
Strengths
34 mcg ivermectin / 28.5 mg pyrantel pamoate / 28.5 mg praziquantel

Indications / Uses

Iverhart Max Chew is approved for dogs to prevent canine heartworm disease for one month after infection and to treat and control labeled roundworm, hookworm, and tapeworm infections.

Administration / How To Give

Administer orally once monthly according to the dog's body-weight band and only under veterinary direction; test dogs for existing heartworm infection before starting prevention.

Warnings / Contraindications

  • Iverhart Max Chew is not effective against adult heartworms; dogs should be tested for existing heartworm infection before starting and again as directed by the label and veterinarian.
  • Use Iverhart Max Chew cautiously in sick, debilitated, or underweight dogs and in dogs below the label's minimum weight range.

Side Effects

Top reported reactions (openFDA): Vomiting, INEFFECTIVE, HEARTWORM LARVAE, Emesis (multiple), Lethargy (see also Central nervous system depression in 'Neurological'), Diarrhoea, Drug dose omission.

FAQ

Dogs

Yes. Roxee shows this as prescription-only.

Chewable tablet

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Pet Owner Quick Guide

Start here first for the safest next-step summary before the deeper medication detail.

Roxee still has limited plain-language guidance for this medication. Use the official documents and your veterinarian's instructions for product-specific details.

Used for:

Your vet decides this. Here's what owners typically ask/watch for.

Dosing note:

Exact dosing depends on your pet's species, weight, and health status. Use your veterinarian's instructions for the exact dose and schedule.

What to watch for:

  • Vomiting (1 reports)
  • very low energy (1 reports)
  • Seizure NOS (1 reports)

When to call the vet:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
  • Facial swelling or hives.
  • Blood in vomit or stool.

What to tell or ask your vet today:

  • Is this medicine the right fit for my pet’s current symptoms?
  • Which warning signs mean I should call back right away?
  • How should I handle missed doses or refusal to take the medicine?

Next actions

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Research brief

Medication Research Insights

A source-aware map of what to know, what is uncertain, and what to verify with your veterinarian.

Source Backed Signals

What to know

Evidence-backed context Limited

Roxee has limited cited overview evidence for Ivermectin 34Mcg, Pyrantel Pamoate 28.5Mg, Praziquantel 28.5Mg; use the official documents and your veterinarian's instructions for product-specific decisions.

Source: openFDA case USA-USFDACVM-2018-US-000032
Safety signal coverage Reported signals

11 tracked reaction signals; 5 reported cases; 1 species group. These are reporting and label-derived signals for interpretation with a veterinarian.

Source: openFDA case USA-USFDACVM-2018-US-000032
Interpretation guardrail Not causation

Adverse-event reports help form a watch list, but they do not prove the medication caused the reaction and they are not a risk ranking between medications.

Evidence tension

Stronger signal Label / review

Official labels, package inserts, and reviewed summaries carry more weight than isolated reports.

Source: openFDA case USA-USFDACVM-2018-US-000032
Weaker signal Reported data

Case reports and openFDA terms are useful for pattern awareness, but they are incomplete, can include multiple exposures, and do not estimate an individual pet's probability of harm.

Reaction signal map

Most reported reactions Top terms

Vomiting (1 reports), Tiredness (lethargy) (1 reports), Seizure NOS (1 reports), Loose stool (1 reports), INEFFECTIVE, HEARTWORM LARVAE (1 reports)

Body systems represented Signal grouping

Digestive (2), Neurologic (3), Other (6)

Species and breed lens

Species represented in reports Species lens

Dog (11 reports)

What your vet may verify

Fit for this patient Vet check

Verify whether Ivermectin 34Mcg, Pyrantel Pamoate 28.5Mg, Praziquantel 28.5Mg fits the pet's species, current diagnosis, age, weight, organ status, pregnancy/lactation status, and concurrent medications.

Evidence limitations Evidence review

Separate label-backed warnings from adverse-event reports and owner observations before changing the plan.

What to watch next

Watch list Owner-safe

Vomiting, very low energy, Seizure NOS

Call sooner if Escalation

Repeated vomiting or diarrhea. Severe lethargy (hard to wake, very low energy). Collapse or fainting.

Bottom line: Use this Ivermectin 34Mcg, Pyrantel Pamoate 28.5Mg, Praziquantel 28.5Mg brief as a structured watch list and source map, not as a reason to start, stop, or change treatment without your veterinarian.
Vet source depth
  1. openFDA case USA-USFDACVM-2018-US-000032 · adverse_reaction · adverse reactions
  2. Patient-selection precaution from the official Iverhart Max Chew label. · safety_warning · warnings contraindications
  3. Structured Product Label · document · documents
  4. Official label · document · documents

Evidence

Review status / Updated / Sources

Review status: Clinical reviewer not listed

Updated: April 22, 2026, 10:09 AM UTC

Sources:
Safety & side effects

Side effects to monitor:

  • Vomiting
  • very low energy
  • Seizure NOS

Most reported reactions:

  • Vomiting (1 reports)
  • Tiredness (lethargy) (1 reports)
  • Seizure NOS (1 reports)

Emergency warning signs:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
Talk to a Vet / Find a Vet Near You Start Symptom Intake

Vet Fast Scan

Source-backed clinical checkpoints for quick review.

FDA-labeled species
Not linked yet
Indication / use
Your vet decides this. Here's what owners typically ask/watch for.
Form / route / dose
Confirm product label and patient-specific plan.
Warnings
No structured warnings linked yet.
Adverse-event caveat
No stored openFDA case explorer rows are linked yet.
Source docs

Quick Facts

Official label facts first, then secondary summaries. Marketing content is separated below.

Species: Both
Manufacturer: Virbac AH, Inc

Adverse Reactions

Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.

Tap or hover a reaction to see what it means in plain language.

Tracked signals
11
Reported cases
5
Serious reports
0
Species represented
1
Grouped by Body System
Digestive (2) · Vomiting, Diarrhea Neurologic (3) · Tiredness (lethargy), Seizure NOS, Lethargy (see also Central nervous system depression in 'Neurological') Other (6) · Loose stool, INEFFECTIVE, HEARTWORM LARVAE, Emesis (multiple)
Most Reported Reactions
Reaction Body system Cases Species Serious cases
Digestive 1 Dog 0
Neurologic 1 Dog 0
Neurologic 1 Dog 0
Other 1 Dog 0
Other 1 Dog 0
Neurologic 0 Dog 0
Other 0 Dog 0
Other 0 Dog 0

Species coverage: Dog (11)

View detailed reaction table
Reaction Body system Species Seriousness Frequency Reports
Digestive Dog Non-serious - 1
Neurologic Dog Non-serious - 1
Neurologic Dog Non-serious - 1
Other Dog Non-serious - 1
Other Dog Non-serious - 1
Neurologic Dog Unknown - -
Other Dog Unknown - -
Other Dog Unknown - -
Other Dog Unknown - -
Digestive Dog Unknown - -
Other Dog Unknown - -
Source metadata:

Source Documents

The most useful source links appear first; full previews and metadata stay in the veterinary/professional layer.

Use original documents to confirm product-specific warnings, ingredients, and handling details with your veterinarian.

Iverhart Max Chew Official Label (DailyMed) Official label / PI · Official label Iverhart Max Chew FDA SPL XML SPL · Structured Product Label

Full source previews and metadata remain in the veterinary/professional layer.

Owner handouts

0
No owner handouts linked yet.

Official label / PI

1

SPL

1

FOI

0
No FOI links yet.

Iverhart Max Chew Official Label (DailyMed)

Official label / PI · Official label

Open original

This source does not expose a safe inline preview. Use the original source link for the full document.

Official Iverhart Max Chew label.

Iverhart Max Chew FDA SPL XML

SPL · Structured Product Label

Open original

This source does not expose a safe inline preview. Use the original source link for the full document.

FDA Structured Product Label XML for Iverhart Max Chew.

Source metadata:
Veterinary reference (advanced)

Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.

At a Glance

Quick facts and links to official labeling and safety signals.

Data freshness
  • Reference facts: Source Roxee | Refreshed Jun 22, 2026, 10:47 AM UTC
    The reference fact projection used for browse cards and quick facts.
Official (FDA)
Identity: Generic ingredient • No FDA branded products linked
Curated brands: Iverhart Max Chew from curated manufacturer/official sources
Manufacturer mapping: Virbac AH, Inc
Catalog species: Both
Safety (openFDA)
Top reactions: Dog 0 • Cat 0 • View
Case summaries: 0
openFDA reports are unverified and do not prove causation.
Diagnosis Codes

Diagnosis-code mappings are not available for this medication yet.

Counseling and Monitoring Highlights

Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.

Top reaction signals
Vomiting (1) Tiredness (lethargy) (1) Seizure NOS (1) Loose stool (1) INEFFECTIVE, HEARTWORM LARVAE (1) Lethargy (see also Central nervous system depression in 'Neurological') (0) Drug dose omission (0) Drug dose administration interval too long (0)

Enriched Documents

Documents are tiered by source trust: Official, Clinical, Manufacturer, Marketing.

Data Sources & Change Log

Every non-trivial field is expected to include provenance and update timestamps.

Official 13 Clinical 3 Manufacturer 0 Marketing 0
Current Field Facts
  • side_effects: Top reported reactions (openFDA): Vomiting, INEFFECTIVE, HEARTWORM LARVAE, Emesis (multiple), Lethargy (see also Central nervous system depression in 'Neurolog… (Clinical, 2026-04-22)
  • side_effects: Top reported reactions (openFDA): Vomiting, INEFFECTIVE, HEARTWORM LARVAE, Emesis (multiple), Lethargy (see also Central nervous system depression in 'Neurolog… (Clinical, 2026-04-15)
  • side_effects: Top reported reactions (openFDA): Vomiting, INEFFECTIVE, HEARTWORM LARVAE, Emesis (multiple), Lethargy (see also Central nervous system depression in 'Neurolog… (Clinical, 2026-04-11)
  • administration: Administer orally once monthly according to the dog's body-weight band and only under veterinary direction; test dogs for existing heartworm infection before s… (Official, 2026-04-22)
  • approval_reference: NADA 141-441 (Official, 2026-04-22)
  • brand_names: Iverhart Max Chew (Official, 2026-04-22)
  • dosage_forms: Chewable tablet (Official, 2026-04-22)
  • drug_profile_type: branded (Official, 2026-04-22)
  • manufacturer_name: Virbac AH, Inc (Official, 2026-04-22)
  • prescription_required: Rx (Official, 2026-04-22)
  • side_effects: Top reported reactions (openFDA): Vomiting, INEFFECTIVE, HEARTWORM LARVAE, Emesis (multiple), Lethargy (see also Central nervous system depression in 'Neurolog… (Official, 2026-02-12)
  • species: Dogs (Official, 2026-04-22)
  • strengths: 34 mcg ivermectin / 28.5 mg pyrantel pamoate / 28.5 mg praziquantel (Official, 2026-04-22)
  • usage: Iverhart Max Chew is approved for dogs to prevent canine heartworm disease for one month after infection and to treat and control labeled roundworm, hookworm, … (Official, 2026-04-22)
Recent Revisions
  • prescription_required updated 2026-06-22 10:47 by curated_loader • Federal law restricts Iverhart Max Chew to use by or on the order of a licensed veterinarian.
  • administration updated 2026-06-22 10:47 by curated_loader • Official dosage, administration, and precaution sections from the Iverhart Max Chew label.
  • strengths updated 2026-06-22 10:47 by curated_loader • 21 CFR 520.1199 lists this tablet strength.
  • dosage_forms updated 2026-06-22 10:47 by curated_loader • Official label describes Iverhart Max Chew as chewable tablets.
  • species updated 2026-06-22 10:47 by curated_loader • Official label states Iverhart Max Chew is for oral use in dogs only.
  • usage updated 2026-06-22 10:47 by curated_loader • Official indication summary from the Iverhart Max Chew label.
  • drug_profile_type updated 2026-06-22 10:47 by curated_loader • Iverhart Max Chew is the branded FDA-approved animal drug for this ivermectin, pyrantel, and praziquantel combination.
  • manufacturer_name updated 2026-06-22 10:47 by curated_loader • Official label identifies Virbac AH, Inc as the labeler.
  • brand_names updated 2026-06-22 10:47 by curated_loader • Official label identifies Iverhart Max Chew as the proprietary product name.
  • approval_reference updated 2026-06-22 10:47 by curated_loader • FDA SPL listing identifies Iverhart Max Chew under NADA 141-441.
  • prescription_required updated 2026-06-22 10:07 by curated_loader • Federal law restricts Iverhart Max Chew to use by or on the order of a licensed veterinarian.
  • administration updated 2026-06-22 10:07 by curated_loader • Official dosage, administration, and precaution sections from the Iverhart Max Chew label.
  • strengths updated 2026-06-22 10:07 by curated_loader • 21 CFR 520.1199 lists this tablet strength.
  • dosage_forms updated 2026-06-22 10:07 by curated_loader • Official label describes Iverhart Max Chew as chewable tablets.
  • species updated 2026-06-22 10:07 by curated_loader • Official label states Iverhart Max Chew is for oral use in dogs only.
  • usage updated 2026-06-22 10:07 by curated_loader • Official indication summary from the Iverhart Max Chew label.
  • drug_profile_type updated 2026-06-22 10:07 by curated_loader • Iverhart Max Chew is the branded FDA-approved animal drug for this ivermectin, pyrantel, and praziquantel combination.
  • manufacturer_name updated 2026-06-22 10:07 by curated_loader • Official label identifies Virbac AH, Inc as the labeler.
  • brand_names updated 2026-06-22 10:07 by curated_loader • Official label identifies Iverhart Max Chew as the proprietary product name.
  • approval_reference updated 2026-06-22 10:07 by curated_loader • FDA SPL listing identifies Iverhart Max Chew under NADA 141-441.

Top Reported Reactions (openFDA)

De-duplicated reaction terms grouped by body system from FDA openFDA reports (not verified; does not prove causation).

Digestive
Vomiting (1) • Dog Diarrhea • Dog

Showing top 5 for Digestive.

Neurologic
Tiredness (1) • Dog Seizure NOS (1) • Dog Tiredness (lethargy) • Dog

Showing top 5 for Neurologic.

Other
Loose stool (1) • Dog INEFFECTIVE, HEARTWORM LARVAE (1) • Dog Drug dose omission • Dog Drug dose administration interval too long • Dog Anuria • Dog

Showing top 5 for Other.

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Adverse Event Case Summaries (openFDA)

These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.

No case-level openFDA reports are linked for this medication yet.

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Overdose Information

No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.

Storage & Handling

No approved storage guidance is linked yet for this ingredient. Use manufacturer packaging and veterinary guidance for handling/storage.

Share Your Thoughts

Let others know your experience or advice regarding this medication.

This medication has not been reviewed by a veterinarian yet.