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Roxee Medication Guide

Maropitant Citrate

Medication reference facts with explicit FDA-approval, off-label, source-limited, and safety context. Roxee does not sell, prescribe, or dispense medications.

Both Reference complete FDA data linked Rx required Tablet Multiple FDA sponsors Official label facts Owner quick guide first

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Data freshness

Reference facts
Reference refreshed
Jun 22, 2026, 10:40 a.m.

These are the reference facts Roxee uses on browse cards and quick facts.

FDA applications
FDA application data refreshed
Jun 22, 2026, 10:40 a.m.

Sponsor, product, and application records imported from Animal Drugs @ FDA.

Safety reports
Safety data refreshed
Jun 22, 2026, 10:42 a.m.

openFDA reaction terms and case summaries are supporting evidence, not proof of causality.

Source timing details
Source timing details
  • Reference facts: Source Roxee | Refreshed Jun 22, 2026, 10:40 AM UTC
    The reference fact projection used for browse cards and quick facts.
  • Animal Drugs @ FDA: Source FDA | Refreshed Jun 22, 2026, 10:40 AM UTC
    Applications/products are imported from FDA export data.
  • Animal Drugs @ FDA previews: Source FDA | Refreshed Feb 9, 2026, 3:05 AM UTC
    Label highlights/doc links are fetched from FDA preview endpoints.
  • openFDA reaction terms: Source FDA openFDA | Refreshed Jun 22, 2026, 10:45 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Jun 22, 2026, 10:45 AM UTC
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Maropitant Citrate

Maropitant Citrate

Drug type: Generic ingredient • Generic profile No FDA branded products linked

Both Tablet Rx required 100% reference complete

Species: Both

Manufacturer: Multiple FDA sponsors

Medication Snapshot

Merged from the current Roxee medication system with field-level provenance, freshness, and completeness tracking.

Maropitant Citrate

Antiemetic used to prevent and treat vomiting (and motion sickness in dogs). Species commonly shown: Both, Dog, Cat.

Generic name
Maropitant Citrate
Brand names
Cerenia® Tablets, Cerenia® Injectable Solution, Maropitant Citrate, Maropitant Citrate Tablets
Manufacturer
Multiple FDA sponsors
Species
Both, Dog, Cat
Dosage forms
Tablet, Liquid (Solution), Injectable Solution, Chewable Tablets
Prescription
Prescription required
Completeness
100%
Validation
Complete
Brand names
Cerenia® Tablets Cerenia® Injectable Solution Maropitant Citrate Maropitant Citrate Tablets
Dosage forms
Tablet Liquid (Solution) Injectable Solution Chewable Tablets

Indications / Uses

Antiemetic used to prevent and treat vomiting (and motion sickness in dogs).

Administration / How To Give

Oral / Injectable

Storage

Store per label; protect injectable from light.

Warnings / Contraindications

Use caution with severe liver disease.

  • Use caution with severe liver disease.

Side Effects

Pain at injection site, lethargy, diarrhea.

FAQ

Both, Dog, Cat

Yes. Roxee shows this as prescription-only.

Tablet, Liquid (Solution), Injectable Solution, Chewable Tablets

Store per label; protect injectable from light.

Source Transparency

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Pet Owner Quick Guide

Start here first for the safest next-step summary before the deeper medication detail.

Used for:

For the prevention of acute vomiting and the prevention of vomiting due to motion sickness in dogs.

Dosing note:

Exact dosing depends on your pet's species, weight, and health status. Use your veterinarian's instructions for the exact dose and schedule.

What to watch for:

  • Use caution with severe liver disease
  • wobbly/unsteady walking (1 reports)
  • Loss of appetite (1 reports)
  • Bladder distension (1 reports)

When to call the vet:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
  • Facial swelling or hives.
  • Blood in vomit or stool.

What to tell or ask your vet today:

  • Is this medicine the right fit for my pet’s current symptoms?
  • Which warning signs mean I should call back right away?
  • How should I handle missed doses or refusal to take the medicine?

Next actions

Research brief

Medication Research Insights

A source-aware map of what to know, what is uncertain, and what to verify with your veterinarian.

Source Backed Signals

What to know

Evidence-backed context Limited

Roxee has limited cited overview evidence for Maropitant Citrate; use the official documents and your veterinarian's instructions for product-specific decisions.

Source: openFDA case USA-USFDACVM-2025-US-070810
Safety signal coverage Reported signals

32 tracked reaction signals; 32 reported cases; 24 serious reports; 2 species groups. These are reporting and label-derived signals for interpretation with a veterinarian.

Source: openFDA case USA-USFDACVM-2025-US-070810
Interpretation guardrail Not causation

Adverse-event reports help form a watch list, but they do not prove the medication caused the reaction and they are not a risk ranking between medications.

Evidence tension

Stronger signal Label / review

Official labels, package inserts, and reviewed summaries carry more weight than isolated reports.

Source: openFDA case USA-USFDACVM-2025-US-070810
Weaker signal Reported data

Case reports and openFDA terms are useful for pattern awareness, but they are incomplete, can include multiple exposures, and do not estimate an individual pet's probability of harm.

Reaction signal map

Most reported reactions Top terms

Unsteady walking (ataxia) (1 reports), Loss of appetite (1 reports), Bladder distension (1 reports), Biting -aggression (1 reports), Behavioral disorder (unspecified) (1 reports)

Body systems represented Signal grouping

Digestive (1), Skin & allergy (2), Neurologic (1), Behavior (3)

Explore supporting adverse reports

Species and breed lens

Species represented in reports Species lens

Dog (19 reports), Cat (13 reports)

Breed metadata in reports Metadata only

Domestic Shorthair (2), Persian (1), Chihuahua (1), Siberian Husky (1). These are report metadata, not proof that a breed is at higher risk.

What your vet may verify

Fit for this patient Vet check

Verify whether Maropitant Citrate fits the pet's species, current diagnosis, age, weight, organ status, pregnancy/lactation status, and concurrent medications.

Evidence limitations Evidence review

Separate label-backed warnings from adverse-event reports and owner observations before changing the plan.

What to watch next

Watch list Owner-safe

Use caution with severe liver disease, wobbly/unsteady walking, Loss of appetite, Bladder distension

Call sooner if Escalation

Repeated vomiting or diarrhea. Severe lethargy (hard to wake, very low energy). Collapse or fainting.

Bottom line: Use this Maropitant Citrate brief as a structured watch list and source map, not as a reason to start, stop, or change treatment without your veterinarian.
Vet source depth
  1. openFDA case USA-USFDACVM-2025-US-070810 · adverse_reaction · adverse reactions
  2. Contraindication source · fda_animal_drugs · warnings contraindications
  3. FDA application profile · official_label · quick facts
  4. FDA application profile · official_label · quick facts
  5. Medication usage source · fda_animal_drugs · quick facts
  6. FOI · document · documents
  7. SPL · document · documents
  8. FOI · document · documents

Evidence

Review status / Updated / Sources

Review status: Clinical reviewer not listed

Updated: February 12, 2026, 7:40 PM UTC

Sources:
Safety & side effects

Side effects to monitor:

  • Use caution with severe liver disease
  • wobbly/unsteady walking
  • Loss of appetite
  • Bladder distension

Most reported reactions:

  • Unsteady walking (ataxia) (1 reports)
  • Loss of appetite (1 reports)
  • Bladder distension (1 reports)
Explore reported case details

Emergency warning signs:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.

Vet Fast Scan

Source-backed clinical checkpoints for quick review.

FDA-labeled species
Cat, Dog
Indication / use
For the prevention of acute vomiting and the prevention of vomiting due to motion sickness in dogs.
Form / route / dose
Form: Chewable Tablets, Injectable Solution, Liquid (Solution), Tablet
Route: Intravenous, Oral, Subcutaneous
Confirm product label and patient-specific plan.
Warnings
  • High: Use caution with severe liver disease.
Adverse-event caveat
openFDA adverse-event cases are reported signals. They are not verified, do not prove causation, and do not estimate a pet's individual risk.

Quick Facts

Official label facts first, then secondary summaries. Marketing content is separated below.

Species: Both
Manufacturer: Multiple FDA sponsors
Form: Chewable Tablets, Injectable Solution, Liquid (Solution), Tablet
Identifiers:
ANADA: 200710 ANADA: 200747 ANADA: 200785 ANADA: 200833 NADA: 141262 NADA: 141263 NDC Package: 11695-7029-1 NDC Package: 11695-7029-2 NDC Package: 11695-7030-1 NDC Package: 11695-7030-2 NDC Package: 11695-7031-1 NDC Package: 11695-7031-2 NDC Package: 11695-7032-1 NDC Package: 11695-7032-2 NDC Package: 11695-7054-1 NDC Package: 11695-7054-2 NDC Package: 11695-7055-1 NDC Package: 11695-7055-2 NDC Package: 11695-7056-1 NDC Package: 11695-7056-2
Source metadata:

Warnings / Contraindications

Use caution with severe liver disease.

  • High: Use caution with severe liver disease.
Source metadata:

Adverse Reactions

Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.

Reported case explorer

Filter stored openFDA reports by pet and report attributes. Counts describe reports in this data set, not risk.

Clear filters
openFDA adverse-event cases are reported signals. They are not verified, do not prove causation, and do not estimate a pet's individual risk.
Stored reports
89
Matching reports
11
Active filters
2
Selected filters
Reaction: Lethargy (see also Central nervous system depression in Neurological) Clear Body system: Digestive Clear
Reset
Showing up to 50 matching reports.

USA-USFDACVM-2025-US-074155

Received 2025-12-16 · MSK · MSK

Serious
Species
Dog
Breed
Terrier - Yorkshire
Size / weight
Under 10 lb (0.395 Kilogram)
Age
Under 1 year (2 Month)
Sex
Female Intact
Region
USA
Reactions
ShakingHypersalivationLethargy (see also Central nervous system depression in Neurological)Head tremorAtaxiaNot eatingNot drinkingDry mucous membraneEosinophiliaThrombocytosisElevated gamma-glutamyl transferase (GGT)HypoglycaemiaHypokalaemiaSeizure NOS
Body systems
OtherDigestiveNeurologic
Outcomes
Ongoing

USA-USFDACVM-2025-US-073489

Received 2025-12-16 · MSK · MSK

Serious
Species
Cat
Breed
Domestic Mediumhair
Size / weight
Under 10 lb (4.3 Kilogram)
Age
1-3 years (1 Year)
Sex
Female Neutered
Region
USA
Reactions
DehydrationFeverLethargy (see also Central nervous system depression in Neurological)AnorexiaIncreased heart rateTachypnoeaDistressNot drinkingOther abnormal test result NOS
Body systems
OtherNeurologicDigestive
Outcomes
Recovered/Normal

USA-USFDACVM-2025-US-072504

Received 2025-12-04 · MSK · MSK

Serious
Species
Dog
Breed
Terrier - Bull - American Pit
Size / weight
50-99 lb (29.03 Kilogram)
Age
1-3 years (2 Year)
Sex
Male Neutered
Region
USA
Reactions
Otitis externaTrigeminus paralysisVomitingCoughMuscle atrophy (see also Muscle wasting)Elevated serum alkaline phosphatase (ALP)Elevated alanine aminotransferase (ALT)HypersalivationUnusual stool colourErythema (for urticaria see Immune SOC)Elevated gamma-glutamyl transferase (GGT)Elevated total bilirubinAbnormal ultrasound findingHepatic fibrosisHepatitisLethargy (see also Central nervous system depression in Neurological)AngioedemaGeneralised rashDyspnoeaIncreased lung soundsLeucocytosis NOSIcterusAbnormal radiograph findingJaw disorder
Body systems
OtherDigestiveSkin & allergyNeurologic
Outcomes
Ongoing

USA-USFDACVM-2025-US-072451

Received 2025-12-01 · MSK · MSK

Serious
Species
Cat
Breed
Domestic Shorthair
Size / weight
10-24 lb (5.69 Kilogram)
Age
4-7 years (7 Year)
Sex
Male Neutered
Region
USA
Reactions
Lethargy (see also Central nervous system depression in Neurological)AnorexiaElevated total bilirubinElevated gamma-glutamyl transferase (GGT)Elevated serum alkaline phosphatase (ALP)Elevated alanine aminotransferase (ALT)JaundiceEnlarged liverHidingNausea
Body systems
NeurologicDigestiveOther
Outcomes
Ongoing

USA-USFDACVM-2025-US-072107

Received 2025-12-01 · MSK · MSK

Serious
Species
Dog
Breed
Shepherd Dog - German
Size / weight
50-99 lb (40.1 Kilogram)
Age
8+ years (10.5 Year)
Sex
Male Neutered
Region
USA
Reactions
VocalisationAbnormal tail posturePain NOSWeight lossDecreased appetiteVomitingChewing disorderPantingTremblingLying downAnxietyExcessive chewing, licking and/or groomingMuscle atrophy (see also Muscle wasting)Musculoskeletal disorder NOSAbnormal radiograph findingSpondylosisJoint effusionElevated gamma-glutamyl transferase (GGT)LymphopeniaLethargy (see also Central nervous system depression in Neurological)Thoracic painDeath by euthanasiaMedication error NOS
Body systems
OtherDigestiveBehaviorNeurologic
Outcomes
Euthanized

USA-USFDACVM-2025-US-071120

Received 2025-12-01 · MSK · MSK

Non-serious
Species
Cat
Breed
Maine Coon
Size / weight
10-24 lb (5.942 Kilogram)
Age
8+ years (8 Year)
Sex
Male Unknown
Region
USA
Reactions
Pain NOSLamenessNot eatingFeverHigh pancreatic-specific lipaseLethargy (see also Central nervous system depression in Neurological)VomitingLack of efficacy - NOS
Body systems
OtherNeurologicDigestiveEffectiveness
Outcomes
Recovered/Normal

USA-USFDACVM-2025-US-071209

Received 2025-11-25 · MSK · MSK

Serious
Species
Dog
Breed
Portuguese Water Dog
Size / weight
50-99 lb (23.406 Kilogram)
Age
4-7 years (6 Year)
Sex
Female Neutered
Region
USA
Reactions
AnorexiaInjection site itchingSwelling NOSLethargy (see also Central nervous system depression in Neurological)Injection site mucopurulent dischargeInjection site swellingInjection site skin discolourationInjection site bruisingInjection site abscessInjection site necrosisSicknessInjection site skin change NOSOther abnormal test result NOS
Body systems
DigestiveSkin & allergyNeurologicOther
Outcomes
Ongoing

USA-USFDACVM-2025-US-069329

Received 2025-11-17 · MSK · MSK

Serious
Species
Cat
Breed
['Siamese', 'Cat (other)']
Size / weight
10-24 lb (5.352 Kilogram)
Age
4-7 years (4 Year)
Sex
Female Unknown
Region
USA
Reactions
AnaphylaxisPantingOpen mouth breathingElevated temperatureEmesis (multiple)HidingLethargy (see also Central nervous system depression in Neurological)Low blood pressureFacial swelling (see also Skin)Local erythema
Body systems
OtherDigestiveNeurologicSkin & allergy
Outcomes
Ongoing

USA-USFDACVM-2025-US-067000

Received 2025-11-14 · MSK · MSK

Serious
Species
Cat
Breed
Domestic Shorthair
Size / weight
Under 10 lb (3.992 Kilogram)
Age
8+ years (13 Year)
Sex
Female Unknown
Region
USA
Reactions
DiarrhoeaDecreased appetiteLethargy (see also Central nervous system depression in Neurological)Bloody diarrhoeaDry mucous membraneOpen mouth breathingUnresponsive to stimuliDecreased haematocritIncreased percentage reticulocytesRegenerative anaemiaIntentional misuseUnderdoseThrombocytopeniaHeart murmurHypersalivation
Body systems
DigestiveNeurologicOther
Outcomes
Ongoing

USA-USFDACVM-2025-US-068234

Received 2025-11-12 · MSK · MSK

Serious
Species
Cat
Breed
Cat (unknown)
Sex
Mixed Unknown
Region
USA
Reactions
DeathHaematocheziaDecreased appetiteRegurgitationLethargy (see also Central nervous system depression in Neurological)DiarrhoeaDeath by euthanasia
Body systems
OtherDigestiveNeurologic
Outcomes
DiedEuthanizedOutcome Unknown

USA-USFDACVM-2025-US-065982

Received 2025-11-03 · MSK · MSK

Serious
Species
Dog
Breed
Dachshund (unspecified)
Size / weight
10-24 lb (9.344 Kilogram)
Age
8+ years (14 Year)
Sex
Male Neutered
Region
USA
Reactions
Lethargy (see also Central nervous system depression in Neurological)AnorexiaPale mucous membraneDecreased haematocritThrombocytopeniaImmune mediated haemolytic anaemiaHyperthermiaHeavy breathingFluid in abdomen NOSWeight lossIntentional misuse
Body systems
NeurologicDigestiveOther
Outcomes
Ongoing

Tap or hover a reaction to see what it means in plain language.

Tracked signals
32
Reported cases
32
Serious reports
24
Species represented
2
Grouped by Body System
Digestive (1) · Loss of appetite Skin & allergy (2) · Hair loss at application site, Application site hair loss Neurologic (1) · Unsteady walking (ataxia) Behavior (3) · Biting -aggression, Behavioral disorder (unspecified), Anxiety Other (25) · Bladder distension, Bilirubinuria, Basophilia
Most Reported Reactions
Reaction Body system Cases Species Serious cases
Neurologic 1 Dog 1
Digestive 1 Dog 1
Other 1 Cat 1
Behavior 1 Dog 1
Behavior 1 Cat 1
Other 1 Cat 1
Other 1 Cat 1
Other 1 Cat 1

Species coverage: Dog (19) Cat (13)

View detailed reaction table
Reaction Body system Species Seriousness Frequency Reports
Neurologic Dog Serious - 1
Digestive Dog Serious - 1
Skin & allergy Cat Non-serious - 1
Other Cat Serious - 1
Behavior Dog Serious - 1
Other Dog Non-serious - 1
Behavior Cat Serious - 1
Other Cat Serious - 1
Other Dog Non-serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Cat Non-serious - 1
Other Cat Serious - 1
Skin & allergy Cat Non-serious - 1
Other Cat Non-serious - 1
Behavior Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Cat Non-serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Non-serious - 1
Other Cat Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Source metadata:

Storage & Handling

Store per label; protect injectable from light.

Source Documents

The most useful source links appear first; full previews and metadata stay in the veterinary/professional layer.

Use original documents to confirm product-specific warnings, ingredients, and handling details with your veterinarian.

Full source previews and metadata remain in the veterinary/professional layer.

Owner handouts

0
No owner handouts linked yet.

Official label / PI

0
No official label or package insert links yet.

SPL

6

FOI

10

Maropitant Citrate Tablets

SPL · SPL

FDA Structured Product Label

Maropitant Citrate Tablets

Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.

Sponsor
Felix Pharmaceuticals Pvt. Ltd.
ANADA
200-833
Status
RX
Form
Chewable Tablets
Route
Oral
Composition / specifications
16 mg, 24 mg, 60 mg, or 160 mg of maropitant as maropitant citrate per tablet

Dogs

Indication

For the prevention of acute vomiting and the prevention of vomiting due to motion sickness in dogs.

Dosage

For Prevention of Acute Vomiting in dogs 2 - 7 months of age: Administer Maropitant Citrate Tablets orally at a minimum dose of 2 mg/kg (0.9 mg/lb) body weight once daily for up to 5 consecutive days.
For Prevention of Acute Vomiting in dogs 7 months of age and older: Administer Maropitant Citrate Tablets orally at a minimum dose of 2 mg/kg (0.9 mg/lb) body weight once daily until resolution of acute vomiting.
For Prevention of Vomiting due to motion sickness in dogs 4 months of age and older: Administer Maropitant Citrate Tablets orally at a minimum dose of 8 mg/kg (3.6 mg/lb) body weight once daily for up to 2 consecutive days.

Maropitant Citrate

SPL · SPL

FDA Structured Product Label

Maropitant Citrate

Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.

Sponsor
Dechra Veterinary Products LLC
ANADA
200-710
Status
RX
Form
Injectable Solution
Route
Intravenous, Subcutaneous
Composition / specifications
Each mL contains 10 mg of maropitant as maropitant citrate

Dogs

Indication

For the prevention and treatment of acute vomiting.

Dosage

Administer 1.0 mg per kilogram (mg/kg) of body weight by subcutaneous or intravenous injection once daily for up to 5 consecutive days.

Cats

Indication

For the treatment of vomiting.

Dosage

Administer 1.0 mg/kg of body weight by subcutaneous or intravenous injection once daily for up to 5 consecutive days.

Maropitant Citrate Tablets

SPL · SPL

FDA Structured Product Label

Maropitant Citrate Tablets

Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.

Sponsor
Felix Pharmaceuticals Pvt. Ltd.
ANADA
200-785
Status
RX
Form
Tablet
Route
Oral
Composition / specifications
16 mg, 24 mg, 60 mg, or 160 mg of maropitant citrate per tablet

Dogs

Indication

For the prevention of acute vomiting and the prevention of vomiting due to motion sickness in dogs.

Dosage

For Prevention of Acute Vomiting in dogs 2 -7 months of age: Administer orally at a minimum dose of 2 mg/kg (0.9 mg/lb) body weight once daily for up to 5 consecutive days.

For Prevention of Acute Vomiting in dogs 7 months of age and older: Administer orally at a minimum dose of 2 mg/kg (0.9 mg/lb) body weight once daily until resolution of acute vomiting.

For Prevention of Vomiting due to motion sickness in dogs 4 months of age and older: Administer orally at a minimum dose of 8 mg/kg (3.6 mg/lb) body weight once daily for up to 2 consecutive days.

Maropitant Citrate

SPL · SPL

FDA Structured Product Label

Maropitant Citrate

Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.

Sponsor
ZYVET AH, Inc.
ANADA
200-747
Status
RX
Form
Tablet
Route
Oral
Species
Dog
Composition / specifications
16, 24, 60, or 160 mg of maropitant as maropitant citrate per tablet

Dogs (2-7 months of age)

Indication

For prevention of acute vomiting.

Dosage

Administer orally at a minimum dose of 2 mg/kg (0.9 mg/lb) body weight once daily for up to 5 consecutive days.

Dogs (7 months of age and older)

Indication

For prevention of acute vomiting.

Dosage

Administer orally at a minimum dose of 2 mg/kg (0.9 mg/lb) body weight once daily until resolution of acute vomiting.

Dogs (4 months of age and older)

Indication

For prevention of vomiting due to motion sickness.

Dosage

Administer orally at a minimum dose of 8 mg/kg (3.6 mg/lb) body weight once daily for up to 2 consecutive days.

Cerenia® Tablets

SPL · SPL

FDA Structured Product Label

Cerenia® Tablets

Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.

Sponsor
Zoetis Inc.
NADA
141-262
Status
RX
Form
Tablet
Route
Oral
Species
Dog
Composition / specifications
Each tablet contains 16, 24, 60, or 160 milligrams (mg) maropitant as maropitant citrate.

Dogs (7 Months of Age and Older)

Indication
For the prevention of acute vomiting.
Dosage
Administer CERENIA Tablets orally at a minimum dose of 2 mg/kg (0.9 mg/lb) body weight once daily until resolution of acute vomiting.
Limitations
For oral use in dogs only. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Dogs (4 Months of Age and Older)

Indication
For the prevention of vomiting due to motion sickness.
Dosage
Administer CERENIA Tablets orally at a minimum dose of 8 mg/kg (3.6 mg/lb) body weight once daily for up to 2 consecutive days
Limitations
For oral use in dogs only. Federal law restricts this drug to use by or on the order of a licensed veterinarian. CERENIA injectable solution should not be used interchangeably with CERENIA tablets for the prevention of vomiting due to motion sickness (8mg/kg).

Dogs (2-7 Months)

Indication
For the prevention of acute vomiting.
Dosage
Administer CERENIA Tablets orally at a minimum dose of 2 mg/kg (0.9 mg/lb) body weight once daily for up to 5 consecutive days
Limitations
For oral use in dogs only. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Cerenia® Injectable Solution

SPL · SPL

FDA Structured Product Label

Cerenia® Injectable Solution

Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.

Sponsor
Zoetis Inc.
NADA
141-263
Status
RX
Form
Liquid (Solution)
Route
Subcutaneous, Intravenous
Species
Dog • Cat
Composition / specifications
Each milliliter of solution contains 10 milligrams (mg) maropitant as maropitant citrate.

Dogs (2-4 Months of Age)

Indication
For Prevention and Treatment of Acute Vomiting in Dogs: Dogs 2-4 Months of Age:
Dosage
Administer subcutaneously at 1 mg/kg (0.45 mg/lb) equal to 0.1 mL/kg (0.1 mL/2.2 lb) of body weight once daily for up to 5 consecutive days.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian. The safe use of CERENIA Injectable Solution has not been evaluated in dogs or cats with gastrointestinal obstruction or that have ingested toxins. The safe use of CERENIA Injectable Solution has not been evaluated in dogs or cats used for breeding, or in pregnant or lactating bitches or queens.

Dogs (4 Months of Age and Older)

Indication
For Prevention of Vomiting in Dogs 4 months of Age and Older Caused by Emetogenic Medications or Chemotherapeutic Agents.
Dosage
Administer intravenously over 1-2 minutes or subcutaneously at 1 mg/kg (0.45 mg/lb) of body weight one time, 45-60 minutes prior to use of emetogenic medications or chemotherapeutic agents.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian. The safe use of CERENIA Injectable Solution has not been evaluated in dogs or cats with gastrointestinal obstruction or that have ingested toxins. The safe use of CERENIA Injectable Solution has not been evaluated in dogs or cats used for breeding, or in pregnant or lactating bitches or queens.
Indication
For Prevention and Treatment of Acute Vomiting in Dogs: Dogs 2-4 Months of Age:
Dosage
Administer intravenously over 1-2 minutes or subcutaneously at 1 mg/kg (0.45 mg/lb) equal to 0.1 mL/1 kg (1 mL/22 lb) of body weight once daily for up to 5 consecutive days.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian. The safe use of CERENIA Injectable Solution has not been evaluated in dogs or cats with gastrointestinal obstruction or that have ingested toxins. The safe use of CERENIA Injectable Solution has not been evaluated in dogs or cats used for breeding, or in pregnant or lactating bitches or queens.

Cats (4 Months of Age and Older)

Indication
For Treatment of Vomiting in Cats 4 Months of Age and Older
Dosage
Administer intravenously over 1-2 minutes or subcutaneously at 1 mg/kg (0.45 mg/lb) equal to 0.1 mL/kg (0.1 mL/2.2 lb) of body weight once daily for up to 5 consecutive days.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian. The safe use of CERENIA Injectable Solution has not been evaluated in dogs or cats with gastrointestinal obstruction or that have ingested toxins. The safe use of CERENIA Injectable Solution has not been evaluated in dogs or cats used for breeding, or in pregnant or lactating bitches or queens.

FOI Summary oA 200-833 Approved January 12, 2026.pdf

FOI · FOI

FOI Summary oA 200-710 Approved December 5, 2025.pdf

FOI · FOI

FOI Summary oA 200-785 Approved June 17, 2024.pdf

FOI · FOI

FOI Summary oA 200-747 Approved March 31, 2023.pdf

FOI · FOI

UCM453543.pdf

FOI · FOI

UCM050060.pdf

FOI · FOI

UCM484493.pdf

FOI · FOI

UCM314823.pdf

FOI · FOI

UCM314825.pdf

FOI · FOI

ucm062313.pdf

FOI · FOI

Veterinary reference (advanced)

Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.

At a Glance

Quick facts and links to official labeling and safety signals.

Data freshness
  • Reference facts: Source Roxee | Refreshed Jun 22, 2026, 10:40 AM UTC
    The reference fact projection used for browse cards and quick facts.
  • Animal Drugs @ FDA: Source FDA | Refreshed Jun 22, 2026, 10:40 AM UTC
    Applications/products are imported from FDA export data.
  • Animal Drugs @ FDA previews: Source FDA | Refreshed Feb 9, 2026, 3:05 AM UTC
    Label highlights/doc links are fetched from FDA preview endpoints.
  • openFDA reaction terms: Source FDA openFDA | Refreshed Jun 22, 2026, 10:45 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Jun 22, 2026, 10:45 AM UTC
Official (FDA)
Identity: Generic ingredient • No FDA branded products linked
No official FDA brand rows linked yet for this ingredient.
Case-reported brands (openFDA): MSK
Catalog species: Both FDA-labeled species: Cat, Dog
Rx/OTC: RX
Form/route: Chewable Tablets, Injectable Solution, Liquid (Solution), Tablet Intravenous, Oral, Subcutaneous
Applications: ANADA 200-833 • ANADA 200-710 • ANADA 200-785 • ANADA 200-747 • NADA 141-262 • NADA 141-263
Documents: 10 (FOI: 10) • SPL: 6 Label highlights Official documents
Safety (openFDA)
Top reactions: Dog 261 Cat 195 View
Case summaries: 89 (showing 8) View
openFDA reports are unverified and do not prove causation.

Explore
Linked using: Fda_Label (0.95), Fda_Label (0.95)

Diagnosis Codes

Diagnosis-code mappings are not available for this medication yet.

Counseling and Monitoring Highlights

Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.

Owner-facing counseling points
  • Use caution with severe liver disease. (Contraindication, High)
Top reaction signals
Unsteady walking (ataxia) (1) Loss of appetite (1) Bladder distension (1) Biting -aggression (1) Behavioral disorder (unspecified) (1) Basophilia (1) Azotaemia (1) Ascites (1)

Identifiers & Packages

Normalized identifiers (NDC/NADA/ANADA) and package metadata from regulator listings.

Identifiers
ANADA: 200710 ANADA: 200747 ANADA: 200785 ANADA: 200833 NADA: 141262 NADA: 141263 NDC Package: 11695-7029-1 NDC Package: 11695-7029-2 NDC Package: 11695-7030-1 NDC Package: 11695-7030-2 NDC Package: 11695-7031-1 NDC Package: 11695-7031-2 NDC Package: 11695-7032-1 NDC Package: 11695-7032-2 NDC Package: 11695-7054-1 NDC Package: 11695-7054-2 NDC Package: 11695-7055-1 NDC Package: 11695-7055-2 NDC Package: 11695-7056-1 NDC Package: 11695-7056-2 NDC Package: 11695-7057-1 NDC Package: 11695-7057-2 NDC Package: 13612-0035-0 NDC Package: 13612-0035-1
Package NDC Product NDC Form / Route Status
11695-7029-1 11695 -
11695-7029-2 11695 -
11695-7030-1 11695 -
11695-7030-2 11695 -
11695-7031-1 11695 -
11695-7031-2 11695 -
11695-7032-1 11695 -
11695-7032-2 11695 -
11695-7054-1 11695 -
11695-7054-2 11695 -
11695-7055-1 11695 -
11695-7055-2 11695 -
11695-7056-1 11695 -
11695-7056-2 11695 -
11695-7057-1 11695 -
11695-7057-2 11695 -
13612-0035-0 13612 -
13612-0035-1 13612 -
17033-004-01 17033 -
17033-006-04 17033 -

Enriched Documents

Documents are tiered by source trust: Official, Clinical, Manufacturer, Marketing.

Data Sources & Change Log

Every non-trivial field is expected to include provenance and update timestamps.

Official 77 Clinical 9 Manufacturer 0 Marketing 0
Current Field Facts
  • contraindications: Use caution with severe liver disease. (Clinical, 2026-02-12)
  • overdose_info: Overdose causes excessive drooling, lethargy, collapse due to low BP. Emergency care includes IV fluids, blood pressure support, and monitoring. (Clinical, 2026-04-12)
  • overdose_info: Overdose causes excessive drooling, lethargy, collapse due to low BP. Emergency care includes IV fluids, blood pressure support, and monitoring. (Clinical, 2026-04-11)
  • overdose_info: Overdose causes excessive drooling, lethargy, collapse due to low BP. Emergency care includes IV fluids, blood pressure support, and monitoring. (Clinical, 2026-02-12)
  • side_effects: Pain at injection site, lethargy, diarrhea. (Clinical, 2026-04-11)
  • storage_handling: Store per label; protect injectable from light. (Clinical, 2026-04-12)
  • storage_handling: Store per label; protect injectable from light. (Clinical, 2026-04-11)
  • storage_handling: Store per label; protect injectable from light. (Clinical, 2026-02-12)
  • usage: Antiemetic used to prevent and treat vomiting (and motion sickness in dogs). (Clinical, 2026-02-12)
  • contraindications: Use caution with severe liver disease. (Official, 2026-04-12)
  • contraindications: Use caution with severe liver disease. (Official, 2026-04-11)
  • indications: Dogs:Â For the prevention and treatment of acute vomiting.Cats:Â For the treatment of vomiting. For the prevention and treatment of acute vomiting in dogs. For… (Official, 2026-06-22)
  • indications: Dogs:Â For the prevention and treatment of acute vomiting.Cats:Â For the treatment of vomiting. For the prevention and treatment of acute vomiting in dogs. For… (Official, 2026-06-22)
  • indications: Dogs:Â For the prevention and treatment of acute vomiting.Cats:Â For the treatment of vomiting. For the prevention and treatment of acute vomiting in dogs. For… (Official, 2026-06-21)
  • indications: Dogs:Â For the prevention and treatment of acute vomiting.Cats:Â For the treatment of vomiting. For the prevention and treatment of acute vomiting in dogs. For… (Official, 2026-06-20)
  • indications: Dogs:Â For the prevention and treatment of acute vomiting.Cats:Â For the treatment of vomiting. For the prevention and treatment of acute vomiting in dogs. For… (Official, 2026-06-13)
  • indications: Dogs:Â For the prevention and treatment of acute vomiting.Cats:Â For the treatment of vomiting. For the prevention and treatment of acute vomiting in dogs. For… (Official, 2026-06-12)
  • indications: Dogs:Â For the prevention and treatment of acute vomiting.Cats:Â For the treatment of vomiting. For the prevention and treatment of acute vomiting in dogs. For… (Official, 2026-06-12)
  • indications: Dogs:Â For the prevention and treatment of acute vomiting.Cats:Â For the treatment of vomiting. For the prevention and treatment of acute vomiting in dogs. For… (Official, 2026-06-11)
  • indications: Dogs:Â For the prevention and treatment of acute vomiting.Cats:Â For the treatment of vomiting. For the prevention and treatment of acute vomiting in dogs. For… (Official, 2026-06-11)
Recent Revisions
  • side_effects updated 2026-04-12 10:05 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-04-12 10:05 by etl_backfill • Backfilled from existing medication fields
  • usage updated 2026-04-12 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-04-11 10:05 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-04-11 10:05 by etl_backfill • Backfilled from existing medication fields
  • usage updated 2026-04-11 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-02-12 19:40 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-02-12 19:40 by etl_backfill • Backfilled from existing medication fields
  • usage updated 2026-02-12 19:40 by etl_backfill • Backfilled from existing medication fields

FDA Products & Applications (Animal Drugs @ FDA)

Official sponsor/proprietary-name/application-status records linked by active ingredient.

Product Sponsor Application Status Published
Maropitant Citrate Tablets
RX
Maropitant
Chewable Tablets Oral
Felix Pharmaceuticals Pvt. Ltd. ANADA 200-833 Approved Feb 2, 2026
Maropitant Citrate
RX
Maropitant
Injectable Solution Intravenous, Subcutaneous
Dechra Veterinary Products LLC ANADA 200-710 Approved Jan 5, 2026
Maropitant Citrate Tablets
RX
Maropitant
Tablet Oral
Felix Pharmaceuticals Pvt. Ltd. ANADA 200-785 Approved Jul 1, 2024
Maropitant Citrate
RX
Maropitant
Tablet Oral
ZYVET AH, Inc. ANADA 200-747 Approved Mar 31, 2023
Cerenia® Tablets
RX
Maropitant
Tablet Oral
Zoetis Inc. NADA 141-262 Approved Jan 31, 2019
Cerenia® Injectable Solution
RX
Maropitant
Liquid (Solution) Subcutaneous, Intravenous
Zoetis Inc. NADA 141-263 Approved Jun 1, 2016

Data source: FDA Animal Drugs @ FDA (public search export).

What It's For (FDA Label Highlights)

Extracted from FDA Animal Drugs @ FDA product labeling. Always confirm details with your veterinarian.

Composition / specifications
16 mg, 24 mg, 60 mg, or 160 mg of maropitant as maropitant citrate per tablet
Dogs
Indication

For the prevention of acute vomiting and the prevention of vomiting due to motion sickness in dogs.

Dosage

For Prevention of Acute Vomiting in dogs 2 - 7 months of age: Administer Maropitant Citrate Tablets orally at a minimum dose of 2 mg/kg (0.9 mg/lb) body weight once daily for up to 5 consecutive days.
For Prevention of Acute Vomiting in dogs 7 months of age and older: Administer Maropitant Citrate Tablets orally at a minimum dose of 2 mg/kg (0.9 mg/lb) body weight once daily until resolution of acute vomiting.
For Prevention of Vomiting due to motion sickness in dogs 4 months of age and older: Administer Maropitant Citrate Tablets orally at a minimum dose of 8 mg/kg (3.6 mg/lb) body weight once daily for up to 2 consecutive days.

Limitations

FDA page: Open in Animal Drugs @ FDA

Composition / specifications
Each mL contains 10 mg of maropitant as maropitant citrate
Dogs
Indication

For the prevention and treatment of acute vomiting.

Dosage

Administer 1.0 mg per kilogram (mg/kg) of body weight by subcutaneous or intravenous injection once daily for up to 5 consecutive days.

Limitations
Cats
Indication

For the treatment of vomiting.

Dosage

Administer 1.0 mg/kg of body weight by subcutaneous or intravenous injection once daily for up to 5 consecutive days.

Limitations

FDA page: Open in Animal Drugs @ FDA

Composition / specifications
16 mg, 24 mg, 60 mg, or 160 mg of maropitant citrate per tablet
Dogs
Indication

For the prevention of acute vomiting and the prevention of vomiting due to motion sickness in dogs.

Dosage

For Prevention of Acute Vomiting in dogs 2 -7 months of age: Administer orally at a minimum dose of 2 mg/kg (0.9 mg/lb) body weight once daily for up to 5 consecutive days.

For Prevention of Acute Vomiting in dogs 7 months of age and older: Administer orally at a minimum dose of 2 mg/kg (0.9 mg/lb) body weight once daily until resolution of acute vomiting.

For Prevention of Vomiting due to motion sickness in dogs 4 months of age and older: Administer orally at a minimum dose of 8 mg/kg (3.6 mg/lb) body weight once daily for up to 2 consecutive days.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Dog
Composition / specifications
16, 24, 60, or 160 mg of maropitant as maropitant citrate per tablet
Dogs (2-7 months of age)
Indication

For prevention of acute vomiting.

Dosage

Administer orally at a minimum dose of 2 mg/kg (0.9 mg/lb) body weight once daily for up to 5 consecutive days.

Limitations
Dogs (7 months of age and older)
Indication

For prevention of acute vomiting.

Dosage

Administer orally at a minimum dose of 2 mg/kg (0.9 mg/lb) body weight once daily until resolution of acute vomiting.

Limitations
Dogs (4 months of age and older)
Indication

For prevention of vomiting due to motion sickness.

Dosage

Administer orally at a minimum dose of 8 mg/kg (3.6 mg/lb) body weight once daily for up to 2 consecutive days.

Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Dog
Composition / specifications
Each tablet contains 16, 24, 60, or 160 milligrams (mg) maropitant as maropitant citrate.
Dogs (7 Months of Age and Older)
Indication
For the prevention of acute vomiting.
Dosage
Administer CERENIA Tablets orally at a minimum dose of 2 mg/kg (0.9 mg/lb) body weight once daily until resolution of acute vomiting.
Limitations
For oral use in dogs only. Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Dogs (4 Months of Age and Older)
Indication
For the prevention of vomiting due to motion sickness.
Dosage
Administer CERENIA Tablets orally at a minimum dose of 8 mg/kg (3.6 mg/lb) body weight once daily for up to 2 consecutive days
Limitations
For oral use in dogs only. Federal law restricts this drug to use by or on the order of a licensed veterinarian. CERENIA injectable solution should not be used interchangeably with CERENIA tablets for the prevention of vomiting due to motion sickness (8mg/kg).
Dogs (2-7 Months)
Indication
For the prevention of acute vomiting.
Dosage
Administer CERENIA Tablets orally at a minimum dose of 2 mg/kg (0.9 mg/lb) body weight once daily for up to 5 consecutive days
Limitations
For oral use in dogs only. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

FDA page: Open in Animal Drugs @ FDA

Species: Dog • Cat
Composition / specifications
Each milliliter of solution contains 10 milligrams (mg) maropitant as maropitant citrate.
Dogs (2-4 Months of Age)
Indication
For Prevention and Treatment of Acute Vomiting in Dogs: Dogs 2-4 Months of Age:
Dosage
Administer subcutaneously at 1 mg/kg (0.45 mg/lb) equal to 0.1 mL/kg (0.1 mL/2.2 lb) of body weight once daily for up to 5 consecutive days.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian. The safe use of CERENIA Injectable Solution has not been evaluated in dogs or cats with gastrointestinal obstruction or that have ingested toxins. The safe use of CERENIA Injectable Solution has not been evaluated in dogs or cats used for breeding, or in pregnant or lactating bitches or queens.
Dogs (4 Months of Age and Older)
Indication
For Prevention of Vomiting in Dogs 4 months of Age and Older Caused by Emetogenic Medications or Chemotherapeutic Agents.
Dosage
Administer intravenously over 1-2 minutes or subcutaneously at 1 mg/kg (0.45 mg/lb) of body weight one time, 45-60 minutes prior to use of emetogenic medications or chemotherapeutic agents.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian. The safe use of CERENIA Injectable Solution has not been evaluated in dogs or cats with gastrointestinal obstruction or that have ingested toxins. The safe use of CERENIA Injectable Solution has not been evaluated in dogs or cats used for breeding, or in pregnant or lactating bitches or queens.
Indication
For Prevention and Treatment of Acute Vomiting in Dogs: Dogs 2-4 Months of Age:
Dosage
Administer intravenously over 1-2 minutes or subcutaneously at 1 mg/kg (0.45 mg/lb) equal to 0.1 mL/1 kg (1 mL/22 lb) of body weight once daily for up to 5 consecutive days.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian. The safe use of CERENIA Injectable Solution has not been evaluated in dogs or cats with gastrointestinal obstruction or that have ingested toxins. The safe use of CERENIA Injectable Solution has not been evaluated in dogs or cats used for breeding, or in pregnant or lactating bitches or queens.
Cats (4 Months of Age and Older)
Indication
For Treatment of Vomiting in Cats 4 Months of Age and Older
Dosage
Administer intravenously over 1-2 minutes or subcutaneously at 1 mg/kg (0.45 mg/lb) equal to 0.1 mL/kg (0.1 mL/2.2 lb) of body weight once daily for up to 5 consecutive days.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian. The safe use of CERENIA Injectable Solution has not been evaluated in dogs or cats with gastrointestinal obstruction or that have ingested toxins. The safe use of CERENIA Injectable Solution has not been evaluated in dogs or cats used for breeding, or in pregnant or lactating bitches or queens.

FDA page: Open in Animal Drugs @ FDA

Usage

Antiemetic used to prevent and treat vomiting (and motion sickness in dogs).

Source: FDA Animal Drugs @ FDA • Reference

Contraindications

Use caution with severe liver disease.

Side Effects

Pain at injection site, lethargy, diarrhea.

Source: FDA openFDA • Reference

Top Reported Reactions (openFDA)

De-duplicated reaction terms grouped by body system from FDA openFDA reports (not verified; does not prove causation).

Digestive
Loss of appetite (1) • Dog

Showing top 5 for Digestive.

Skin & allergy
Hair loss at application site (1) • Cat Application site hair loss (1) • Cat

Showing top 5 for Skin & allergy.

Neurologic
Unsteady walking (1) • Dog

Showing top 5 for Neurologic.

Behavior
Biting -aggression (1) • Dog Behavioral disorder (1) • Cat Anxiety (1) • Dog

Showing top 5 for Behavior.

Other
Bladder distension (1) • Cat Bilirubinuria (1) • Dog Basophilia (1) • Cat Bacterial skin infection NOS (1) • Dog Azotaemia (1) • Cat
Show more (20)
Ascites (1) • Cat Arthritis (1) • Cat Arrhythmia (1) • Cat Application site excoriation (1) • Cat Angioedema (1) • Dog Anaphylaxis (1) • Dog Anaphylactoid reaction (1) • Dog Anaemia NOS (1) • Cat Allergic reaction (1) • Dog Agitation (1) • Dog Agglutination test, positive (1) • Dog Accidental exposure (1) • Cat Abnormal ultrasound finding (1) • Dog Abnormal tail posture (1) • Dog Abnormal radiograph finding (1) • Dog Abnormal posture NOS (1) • Dog Abnormal histology NOS (1) • Dog Abnormal cytology (1) • Cat Abdominal pain (1) • Dog Abdominal discomfort (1) • Dog

Showing top 5 for Other.

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Adverse Event Case Summaries (openFDA)

These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.

Cat, Persian, Male, 12.5 year, 4.4 kilogram • Drug: MSK, Injection, Subcutaneous, Dose: 0.44 mL per animal, Frequency: 6 per day • Reactions: Intentional misuse, Lack of efficacy - NOS, Death by euthanasia, Gait abnormality, Lumbar pain • Outcome: Euthanized

  • Report ID: USA-USFDACVM-2025-US-075165
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 12.50 Year
  • Weight: 4.400 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Subcutaneous
  • Form: Injection
  • Dose: 0.44 mL per animal
  • Frequency: 6 per day
Reactions Reported:
Intentional misuse Lack of efficacy - NOS Death by euthanasia Gait abnormality Lumbar pain
Outcomes: Euthanized

Dog, Chihuahua, Male, 12 year, 3.084 kilogram • Drug: MSK, Tablet, Unknown • Reactions: Seizure NOS, Lateral recumbency, Unresponsive to stimuli, Bradycardia • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2025-US-075262
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 12.00 Year
  • Weight: 3.084 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Tablet
Reactions Reported:
Seizure NOS Lateral recumbency Unresponsive to stimuli Bradycardia
Outcomes: Recovered/Normal

Dog, Siberian Husky, Male, 9 year, 21.682 kilogram • Drug: MSK, Injection, Subcutaneous, Dose: 2.20 mL per animal • Reactions: Injection site lesion, Crust, Injection site ulcer, Injection site erythema, Injection site discharge NOS • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-075214
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 9.00 Year
  • Weight: 21.682 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Subcutaneous
  • Form: Injection
  • Dose: 2.20 mL per animal
Reactions Reported:
Injection site lesion Crust Injection site ulcer Injection site erythema Injection site discharge NOS
Outcomes: Ongoing

Cat, Domestic Shorthair, Female, 15 year, 3.302 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Elevated symmetrical dimethylarginine, Elevated creatinine, Elevated serum alkaline phosphatase, Weight loss, Accidental exposure… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-075358
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 15.00 Year
  • Weight: 3.302 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Unassigned
Reactions Reported:
Elevated symmetrical dimethylarginine Elevated creatinine Elevated serum alkaline phosphatase Weight loss Accidental exposure Anaemia NOS
Outcomes: Ongoing

Cat, Domestic Shorthair, Female, 7 month, 3.08 kilogram • Drug: MSK, Unknown • Reactions: Fever, Cough, productive, Weight loss, Breathing difficulty, Abnormal radiograph finding… • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2025-US-075237
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 7.00 Month
  • Weight: 3.080 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Fever Cough, productive Weight loss Breathing difficulty Abnormal radiograph finding Pulmonary disorder NOS Tiredness (lethargy) Sedation Kidney atrophy Bilirubinuria Elevated mean corpuscular haemoglobin concentration Enlarged kidney Elevated mean corpuscular volume Eosinopenia Low serum alkaline phosphatase Neutropenia Discoloured urine Monocytosis Lymphopenia Elevated amylase Elevated alanine aminotransferase Low creatinine Hyponatremia Other abnormal test result NOS Elevated total bilirubin Hyperglycaemia Lymphocytosis Neutrophilia Leucocytosis NOS Basophilia
Outcomes: Recovered/Normal

Dog, ['Retriever - Golden', 'Beagle', 'Chow Chow'], Male, 11 year, 19.504 kilogram • Drug: MSK, Tablet, Oral • Reactions: Unsteady walking (ataxia), Vestibular disorder NOS, Weight loss, Head tilt - neurological disorder, Low vision… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-075189
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 11.00 Year
  • Weight: 19.504 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet
Reactions Reported:
Unsteady walking (ataxia) Vestibular disorder NOS Weight loss Head tilt - neurological disorder Low vision Urinary incontinence Unable to rise Urinary tract infection Polydipsia Horizontal nystagmus Generalised weakness Depression
Outcomes: Ongoing

Dog, Setter - Irish Red, Male, 9 year, 38 kilogram • Drug: MSK, Tablet, Oral, Dose: 80 Milligram per dose, Frequency: 24 per hour • Reactions: Inappetence, Elevated liver enzymes NOS, Tiredness (lethargy), Polydipsia, Polyuria… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-075441
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 9.00 Year
  • Weight: 38.000 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet
  • Dose: 80 Milligram per dose
  • Frequency: 24 per hour
Reactions Reported:
Inappetence Elevated liver enzymes NOS Tiredness (lethargy) Polydipsia Polyuria Icterus
Outcomes: Ongoing

Dog, Retriever - Labrador, Male, 11.08 year, 30.5 kilogram • Drug: MSK, Unknown • Reactions: Ear infection NOS, Loss of appetite, Nausea, Vomiting, Polycythaemia… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-074697
  • Serious AE: No
  • Treated For AE: No
  • Sex: Male
  • Age: 11.08 Year
  • Weight: 30.500 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Ear infection NOS Loss of appetite Nausea Vomiting Polycythaemia Elevated haemoglobin Increased percentage reticulocytes Elevated mean corpuscular volume Elevated alanine aminotransferase Elevated serum alkaline phosphatase Elevated gamma-glutamyl transferase Elevated cholesterol Hyperproteinaemia Elevated total bilirubin Elevated blood urea nitrogen Abnormal ultrasound finding Abnormal histology NOS Other abnormal test result NOS
Outcomes: Ongoing

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Overdose Information

Overdose causes excessive drooling, lethargy, collapse due to low BP. Emergency care includes IV fluids, blood pressure support, and monitoring.

Storage & Handling

Store per label; protect injectable from light.

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This medication has not been reviewed by a veterinarian yet.