Start triage first, then route to emergency care.
Need urgent help? Start triage first, then route to emergency care.
Roxee Medication Guide
Medication reference facts with explicit FDA-approval, off-label, source-limited, and safety context. Roxee does not sell, prescribe, or dispense medications.
Veterinary professional?
These are the reference facts Roxee uses on browse cards and quick facts.
Sponsor, product, and application records imported from Animal Drugs @ FDA.
openFDA reaction terms and case summaries are supporting evidence, not proof of causality.
Drug type: Generic ingredient • Branded profile • FDA branded products available
Species: Both
Manufacturer: Multiple FDA labelers
Merged from the current Roxee medication system with field-level provenance, freshness, and completeness tracking.
Antibiotic/antiprotozoal used for certain GI infections and inflammation. Species commonly shown: Both, Dog.
Antibiotic/antiprotozoal used for certain GI infections and inflammation.
Oral
Store at room temperature.
Use caution with liver disease. Avoid overdosing.
GI upset. High doses can cause neurologic signs (ataxia, tremors).
Choose a pet, confirm current or past, and optionally add reminder notes.
Sign in to save this medication to your pet profile.
Sign in to continueStart here first for the safest next-step summary before the deeper medication detail.
Used for:
For the treatment of Giardia duodenalis infection in dogs.
Dosing note:
Exact dosing depends on your pet's species, weight, and health status. Use your veterinarian's instructions for the exact dose and schedule.
What to watch for:
When to call the vet:
What to tell or ask your vet today:
A source-aware map of what to know, what is uncertain, and what to verify with your veterinarian.
Roxee has limited cited overview evidence for Metronidazole; use the official documents and your veterinarian's instructions for product-specific decisions.
32 tracked reaction signals; 32 reported cases; 20 serious reports; 2 species groups. These are reporting and label-derived signals for interpretation with a veterinarian.
Adverse-event reports help form a watch list, but they do not prove the medication caused the reaction and they are not a risk ranking between medications.
Official labels, package inserts, and reviewed summaries carry more weight than isolated reports.
Case reports and openFDA terms are useful for pattern awareness, but they are incomplete, can include multiple exposures, and do not estimate an individual pet's probability of harm.
Unsteady walking (ataxia) (1 reports), Decreased mean corpuscular volume (1 reports), Decreased mean corpuscular haemoglobin concentration (1 reports), Decreased haemoglobin (1 reports), Decreased drinking (1 reports)
Digestive (2), Skin & allergy (1), Neurologic (1), Behavior (2)
Dog (19 reports), Cat (13 reports)
Terrier - Bull - American Pit (2), Domestic Shorthair (1), Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) (1), ['Chihuahua', 'Mixed (Dog)'] (1). These are report metadata, not proof that a breed is at higher risk.
Verify whether Metronidazole fits the pet's species, current diagnosis, age, weight, organ status, pregnancy/lactation status, and concurrent medications.
Separate label-backed warnings from adverse-event reports and owner observations before changing the plan.
Use caution with liver disease, Avoid overdosing, wobbly/unsteady walking, Decreased mean corpuscular volume, Decreased mean corpuscular haemoglobin concentration
Repeated vomiting or diarrhea. Severe lethargy (hard to wake, very low energy). Collapse or fainting.
Review status / Updated / Sources
Review status: Clinical reviewer not listed
Updated: February 12, 2026, 7:40 PM UTC
Side effects to monitor:
Most reported reactions:
Emergency warning signs:
Source-backed clinical checkpoints for quick review.
Official label facts first, then secondary summaries. Marketing content is separated below.
Use caution with liver disease. Avoid overdosing.
Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.
Filter stored openFDA reports by pet and report attributes. Counts describe reports in this data set, not risk.
Received 2025-12-19 · MSK · MSK
Received 2025-12-02 · MSK · MSK
Received 2025-12-02 · MSK · MSK
Received 2025-11-14 · MSK · MSK
Tap or hover a reaction to see what it means in plain language.
| Reaction | Body system | Cases | Species | Serious cases |
|---|---|---|---|---|
| Neurologic | 1 | Cat | 1 | |
| Other | 1 | Cat | 1 | |
| Other | 1 | Cat | 1 | |
| Other | 1 | Cat | 1 | |
| Other | 1 | Dog | 1 | |
| Other | 1 | Dog | 1 | |
| Other | 1 | Dog | 1 | |
| Digestive | 1 | Cat | 1 |
Species coverage: Dog (19) Cat (13)
| Reaction | Body system | Species | Seriousness | Frequency | Reports |
|---|---|---|---|---|---|
| Neurologic | Cat | Serious | - | 1 | |
| Other | Dog | Non-serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Other | Dog | Non-serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Digestive | Cat | Serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Behavior | Dog | Non-serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Dog | Non-serious | - | 1 | |
| Digestive | Dog | Serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Other | Dog | Non-serious | - | 1 | |
| Behavior | Cat | Non-serious | - | 1 | |
| Other | Dog | Non-serious | - | 1 | |
| Other | Cat | Non-serious | - | 1 | |
| Skin & allergy | Cat | Non-serious | - | 1 | |
| Other | Cat | Non-serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Dog | Non-serious | - | 1 | |
| Other | Dog | Non-serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Cat | Serious | - | 1 |
Store at room temperature.
The most useful source links appear first; full previews and metadata stay in the veterinary/professional layer.
Use original documents to confirm product-specific warnings, ingredients, and handling details with your veterinarian.
Full source previews and metadata remain in the veterinary/professional layer.
SPL · SPL
Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.
For the treatment of Giardia duodenalis infection in dogs.
25 mg/kg (11.3 mg/lb) of body weight, using the supplied syringe, twice daily for five consecutive days
SPL · Structured Product Label
SPL · Structured Product Label
SPL · Structured Product Label
SPL · Structured Product Label
SPL · Structured Product Label
FOI · FOI
Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.
Quick facts and links to official labeling and safety signals.
Diagnosis-code mappings are not available for this medication yet.
Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.
Normalized identifiers (NDC/NADA/ANADA) and package metadata from regulator listings.
| Package NDC | Product NDC | Form / Route | Status |
|---|---|---|---|
| 17163-015-16 | 17163 | - | |
| 17163-016-17 | 17163 | - | |
| 43457-537-25 | 43457 | - | |
| 46144-602-01 | 46144 | - | |
| 51311-034-10 | 51311 | - | |
| 51311-034-30 | 51311 | - | |
| 53745-016-01 | 53745 | - | |
| 53745-016-02 | 53745 | - | |
| 55999-081-12 | 55999 | - | |
| 55999-081-15 | 55999 | - | |
| 55999-081-18 | 55999 | - | |
| 55999-081-56 | 55999 | - | |
| 55999-081-57 | 55999 | - | |
| 62157-529-01 | 62157 | - | |
| 63732-2047-9 | 63732 | - | |
| 73309-199-01 | 73309 | - | |
| 86184-255-01 | 86184 | - |
Documents are tiered by source trust: Official, Clinical, Manufacturer, Marketing.
Every non-trivial field is expected to include provenance and update timestamps.
Official sponsor/proprietary-name/application-status records linked by active ingredient.
| Product | Sponsor | Application | Status | Published |
|---|---|---|---|---|
|
AYRADIA™
RX
Metronidazole
Suspension
• Oral
|
Virbac AH, Inc. | NADA 141-572 | Approved | Mar 26, 2024 |
Data source: FDA Animal Drugs @ FDA (public search export).
Extracted from FDA Animal Drugs @ FDA product labeling. Always confirm details with your veterinarian.
For the treatment of Giardia duodenalis infection in dogs.
25 mg/kg (11.3 mg/lb) of body weight, using the supplied syringe, twice daily for five consecutive days
FDA page: Open in Animal Drugs @ FDA
Antibiotic/antiprotozoal used for certain GI infections and inflammation.
Source: FDA Animal Drugs @ FDA • Reference
Use caution with liver disease. Avoid overdosing.
GI upset. High doses can cause neurologic signs (ataxia, tremors).
Source: FDA openFDA • Reference
De-duplicated reaction terms grouped by body system from FDA openFDA reports (not verified; does not prove causation).
Showing top 5 for Digestive.
Showing top 5 for Skin & allergy.
Showing top 5 for Neurologic.
Showing top 5 for Behavior.
Showing top 5 for Other.
Data source: FDA openFDA Animal & Veterinary adverse event reports.
These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.
Cat, Domestic Shorthair, Male, 9.5 year, 5.09 kilogram • Drug: MSK, Oral • Reactions: Application site hair loss, Application site bleeding, Application site reddening • Outcome: Outcome Unknown
Dog, Terrier - Bull - American Pit, Male, 7 year, 37 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Loose stool, Vomiting, Decreased appetite, Decreased drinking, Medication error NOS… • Outcome: Ongoing
Dog, Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog), Male, 8 year, 14.061 kilogram • Drug: MSK, Tablet, Oral, Dose: 125 Milligram per dose, Frequency: 12 per hour • Reactions: Haematuria, Stranguria, Pollakiuria, Urine abnormalities NOS, Bilirubinuria… • Outcome: Recovered/Normal
Dog, ['Chihuahua', 'Mixed (Dog)'], Male, 7 year, 2.268 kilogram • Drug: MSK, Oral • Reactions: Obtunded, Hypothermia, Hypotension, Hypoglycaemia, Cardiorespiratory arrest… • Outcome: Euthanized
Dog, Retriever - Labrador, Female, 11 year, 34.292 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Tiredness (lethargy), Medication error NOS, Unsteady walking (ataxia), Hyperactivity, Tremors • Outcome: Recovered/Normal
Dog, Terrier - Bull, Female, 7 year, 17.6 kilogram • Drug: MSK, Unknown • Reactions: Leucopenia NOS, Anaemia NOS, Hypoalbuminaemia, Neutropenia, Pyoderma… • Outcome: Ongoing
Dog, Corso Dog, Male, 5 year, 63.5 kilogram • Drug: MSK, Unknown • Reactions: Urination, Excessive thirst, Inappropriate urination • Outcome: Outcome Unknown
Dog, Terrier - Bull - American Pit, Male, 2 year, 29.03 kilogram • Drug: MSK, Unassigned, Oral • Reactions: Otitis externa, Trigeminus paralysis, Vomiting, Cough, Muscle atrophy… • Outcome: Ongoing
Data source: FDA openFDA Animal & Veterinary adverse event reports.
No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.
Store at room temperature.
Let others know your experience or advice regarding this medication.
This medication has not been reviewed by a veterinarian yet.