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Roxee Meds Catalog

Phenylpropropanolamine Hcl

Medication catalog facts with explicit FDA-approval, off-label, source-limited, and safety context.

Both Source review pending Source coverage pending Owner quick guide first
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Data freshness

Storefront facts
Source review pending
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Roxee is still reviewing source support for this medication profile.

FDA applications
Regulatory match pending
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Roxee has safety or ingredient evidence for this medication, but a regulatory product/application match is still pending.

Safety reports
Safety data refreshed
May 5, 2026, 10:01 a.m.

openFDA reaction terms and case summaries are supporting evidence, not proof of causality.

Source timing details
Source timing details
  • Storefront facts: Source Roxee | Refreshed May 5, 2026, 10:05 AM UTC
    The storefront fact projection used for browse cards and quick facts.
  • openFDA reaction terms: Source FDA openFDA | Refreshed May 5, 2026, 10:04 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed May 5, 2026, 10:04 AM UTC

Evidence

Reviewed / Updated / Sources

Reviewed by: Not available

Last reviewed: April 15, 2026

Updated: April 15, 2026, 10:04 AM UTC

Sources:
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Phenylpropropanolamine Hcl

Phenylpropropanolamine Hcl

Drug type: Generic ingredient • Generic profile • Source coverage pending

Both 80% storefront ready

Species: Both

Approval status: Source coverage pending. Roxee has limited supporting content for this record, but no on-page official FDA animal-drug document is linked yet. Treat it as source-limited until the ETL backfill adds official coverage.

Medication Snapshot

Merged from the current Roxee medication system with field-level provenance, freshness, and completeness tracking.

Phenylpropropanolamine Hcl

Senvelgo (velagliflozin oral solution) is approved in cats for control of hyperglycemia associated with diabetes mellitus. Species commonly shown: Both.

Generic name
Phenylpropropanolamine Hcl
Species
Both
Completeness
80%
Validation
Incomplete

Indications / Uses

Senvelgo (velagliflozin oral solution) is approved in cats for control of hyperglycemia associated with diabetes mellitus.

Side Effects

Top reported reactions (openFDA): Vomiting, Overdose, Underdose, Lack of efficacy - NOS, Panting, Emesis (multiple).

FAQ

Both

Source Transparency

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Pet Owner Quick Guide

Start here first for the safest next-step summary before the deeper medication detail.

Roxee still has limited plain-language guidance for this medication. Use the official documents and your veterinarian's instructions for product-specific details.

Used for:

Your vet decides this. Here's what owners typically ask/watch for.

Dosing note:

Exact dosing depends on your pet's species, weight, and health status. Use your veterinarian's instructions for the exact dose and schedule.

What to watch for:

  • wobbly/unsteady walking (1 reports)
  • Loss of appetite (1 reports)
  • Hyperkalaemia (1 reports)

When to call the vet:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
  • Facial swelling or hives.
  • Blood in vomit or stool.

What to tell or ask your vet today:

  • Is this medicine the right fit for my pet’s current symptoms?
  • Which warning signs mean I should call back right away?
  • How should I handle missed doses or refusal to take the medicine?
Major cautions & emergency warning signs

Side effects to monitor:

  • wobbly/unsteady walking
  • Loss of appetite
  • Hyperkalaemia

Most reported reactions:

  • Unsteady walking (ataxia) (1 reports)
  • Loss of appetite (1 reports)
  • Hyperkalaemia (1 reports)

Emergency warning signs:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
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Quick Facts

Official label facts first, then secondary summaries. Marketing content is separated below.

Species: Both
Manufacturer: Manufacturer not confirmed

Adverse Reactions

Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.

Tap or hover a reaction to see what it means in plain language.

Tracked signals
32
Reported cases
32
Serious reports
26
Species represented
2
Grouped by Body System
Digestive (3) · Vomiting, Loss of appetite, Diarrhea Neurologic (1) · Unsteady walking (ataxia) Behavior (3) · Biting -aggression, Behavioral disorder (unspecified), Anxiety Other (25) · Hyperkalaemia, High leg gait, Growling
Most Reported Reactions
Reaction Body system Cases Species Serious cases
Neurologic 1 Dog 1
Digestive 1 Dog 1
Other 1 Dog 1
Other 1 Dog 1
Other 1 Dog 1
Other 1 Dog 1
Other 1 Dog 1
Other 1 Dog 1

Species coverage: Dog (28) Cat (4)

View detailed reaction table
Reaction Body system Species Seriousness Frequency Reports
Digestive Dog Non-serious - 1
Neurologic Dog Serious - 1
Digestive Dog Serious - 1
Other Dog Serious - 1
Other Dog Non-serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Non-serious - 1
Other Cat Non-serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Non-serious - 1
Digestive Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Behavior Dog Serious - 1
Behavior Dog Serious - 1
Other Dog Serious - 1
Behavior Dog Serious - 1
Other Dog Serious - 1
Other Cat Non-serious - 1
Other Cat Serious - 1
Other Dog Serious - 1
Source metadata:
Veterinary reference (advanced)

Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.

At a Glance

Quick facts and links to official labeling and safety signals.

Data freshness
  • Storefront facts: Source Roxee | Refreshed May 5, 2026, 10:05 AM UTC
    The storefront fact projection used for browse cards and quick facts.
  • openFDA reaction terms: Source FDA openFDA | Refreshed May 5, 2026, 10:04 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed May 5, 2026, 10:04 AM UTC
Official (FDA)
Identity: Generic ingredient • No FDA branded products linked
No official FDA brand rows linked yet for this ingredient.
Case-reported brands (openFDA): MSK
Catalog species: Both
Safety (openFDA)
Top reactions: Dog 46 • Cat 0 • View
Case summaries: 8 (showing 8) • View
openFDA reports are unverified and do not prove causation.
Diagnosis Codes

Diagnosis-code mappings are not available for this medication yet.

Counseling and Monitoring Highlights

Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.

Top reaction signals
Unsteady walking (ataxia) (1) Loss of appetite (1) Hyperkalaemia (1) Growling (1) Glazed eye (1) Frequent urination (1) Falling (1) Elevated symmetrical dimethylarginine (1)

Data Sources & Change Log

Every non-trivial field is expected to include provenance and update timestamps.

Official 15 Clinical 5 Manufacturer 0 Marketing 0
Current Field Facts
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-21)
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-20)
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-19)
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-16)
  • side_effects: Top reported reactions (openFDA): Vomiting, Overdose, Underdose, Lack of efficacy - NOS, Panting, Emesis (multiple). (Clinical, 2026-04-11)
  • side_effects: Top reported reactions (openFDA): Vomiting, Overdose, Underdose, Lack of efficacy - NOS, Panting, Emesis (multiple). (Official, 2026-05-05)
  • side_effects: Top reported reactions (openFDA): Vomiting, Overdose, Underdose, Lack of efficacy - NOS, Panting, Emesis (multiple). (Official, 2026-05-03)
  • side_effects: Top reported reactions (openFDA): Vomiting, Overdose, Underdose, Lack of efficacy - NOS, Panting, Emesis (multiple). (Official, 2026-04-30)
  • side_effects: Top reported reactions (openFDA): Vomiting, Overdose, Underdose, Lack of efficacy - NOS, Panting, Emesis (multiple). (Official, 2026-04-29)
  • side_effects: Top reported reactions (openFDA): Vomiting, Overdose, Underdose, Lack of efficacy - NOS, Panting, Emesis (multiple). (Official, 2026-04-28)
  • side_effects: Top reported reactions (openFDA): Vomiting, Overdose, Underdose, Lack of efficacy - NOS, Panting, Emesis (multiple). (Official, 2026-04-27)
  • side_effects: Top reported reactions (openFDA): Vomiting, Overdose, Underdose, Lack of efficacy - NOS, Panting, Emesis (multiple). (Official, 2026-04-26)
  • side_effects: Top reported reactions (openFDA): Vomiting, Overdose, Underdose, Lack of efficacy - NOS, Panting, Emesis (multiple). (Official, 2026-04-25)
  • side_effects: Top reported reactions (openFDA): Vomiting, Overdose, Underdose, Lack of efficacy - NOS, Panting, Emesis (multiple). (Official, 2026-04-17)
  • side_effects: Top reported reactions (openFDA): Vomiting, Overdose, Underdose, Lack of efficacy - NOS, Panting, Emesis (multiple). (Official, 2026-04-15)
  • side_effects: Top reported reactions (openFDA): Vomiting, Overdose, Underdose, Lack of efficacy - NOS, Panting, Emesis (multiple). (Official, 2026-02-12)
  • usage: Senvelgo (velagliflozin oral solution) is approved in cats for control of hyperglycemia associated with diabetes mellitus. (Official, 2026-04-21)
  • usage: Senvelgo (velagliflozin oral solution) is approved in cats for control of hyperglycemia associated with diabetes mellitus. (Official, 2026-04-20)
  • usage: Senvelgo (velagliflozin oral solution) is approved in cats for control of hyperglycemia associated with diabetes mellitus. (Official, 2026-04-19)
  • usage: Senvelgo (velagliflozin oral solution) is approved in cats for control of hyperglycemia associated with diabetes mellitus. (Official, 2026-04-16)
Recent Revisions
  • side_effects updated 2026-05-05 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-05-03 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-04-30 10:09 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-04-29 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-04-28 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-04-27 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-04-26 10:06 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-04-25 10:05 by etl_backfill • Backfilled from existing medication fields
  • monitoring updated 2026-04-21 10:07 by curated_loader • Clinical monitoring context for feline diabetes management.
  • usage updated 2026-04-21 10:07 by curated_loader • Usage statement from FDA warning letter and approved-product context.
  • drug_profile_type updated 2026-04-21 10:07 by curated_loader • FDA source confirms Senvelgo as a branded approved product.
  • manufacturer_name updated 2026-04-21 10:07 by curated_loader • FDA warning letter identifies the approved sponsor/manufacturer.
  • brand_names updated 2026-04-21 10:07 by curated_loader • FDA warning letter references Senvelgo as the approved animal drug.
  • approval_reference updated 2026-04-21 10:07 by curated_loader • Official FDA application reference for Senvelgo.
  • monitoring updated 2026-04-20 10:09 by curated_loader • Clinical monitoring context for feline diabetes management.
  • usage updated 2026-04-20 10:09 by curated_loader • Usage statement from FDA warning letter and approved-product context.
  • drug_profile_type updated 2026-04-20 10:09 by curated_loader • FDA source confirms Senvelgo as a branded approved product.
  • manufacturer_name updated 2026-04-20 10:09 by curated_loader • FDA warning letter identifies the approved sponsor/manufacturer.
  • brand_names updated 2026-04-20 10:09 by curated_loader • FDA warning letter references Senvelgo as the approved animal drug.
  • approval_reference updated 2026-04-20 10:09 by curated_loader • Official FDA application reference for Senvelgo.

Top Reported Reactions (openFDA)

De-duplicated reaction terms grouped by body system from FDA openFDA reports (not verified; does not prove causation).

Digestive
Vomiting (1) • Dog Loss of appetite (1) • Dog Diarrhea (1) • Dog

Showing top 5 for Digestive.

Neurologic
Unsteady walking (1) • Dog

Showing top 5 for Neurologic.

Behavior
Biting -aggression (1) • Dog Behavioral disorder (1) • Dog Anxiety (1) • Dog

Showing top 5 for Behavior.

Other
Hyperkalaemia (1) • Dog High leg gait (1) • Dog Growling (1) • Dog Glazed eye (1) • Dog Frequent urination (1) • Dog
Show more (20)
Food allergy (1) • Dog Foaming at the mouth (1) • Cat Falling (1) • Dog Elevated symmetrical dimethylarginine (1) • Dog Elevated serum alkaline phosphatase (1) • Dog Elevated renal parameters (1) • Dog Elevated blood urea nitrogen (1) • Dog Elevated alanine aminotransferase (1) • Dog Drug administration duration too long (1) • Dog Difficulty standing (1) • Dog Difficulty going up/down stairs (1) • Dog Death (1) • Dog Cough (1) • Dog Cognitive disorder NOS (1) • Dog Bradycardia (1) • Cat Balance problem (1) • Dog Agitation (1) • Dog Administration error NOS (1) • Cat Accidental exposure (1) • Cat Abnormal posture NOS (1) • Dog

Showing top 5 for Other.

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Adverse Event Case Summaries (openFDA)

These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.

Dog, Shepherd Dog - German, Female, 11 year, 20.865 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Vomiting, Not eating, Tiredness (lethargy), Reluctant to move, Seizure NOS • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-075421
  • Serious AE: Yes
  • Treated For AE: No
  • Sex: Female
  • Age: 11.00 Year
  • Weight: 20.865 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Unassigned
Reactions Reported:
Vomiting Not eating Tiredness (lethargy) Reluctant to move Seizure NOS
Outcomes: Ongoing

Dog, Bulldog - English, Female, 11.2 year, 29.94 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Urinary incontinence • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-075305
  • Serious AE: No
  • Treated For AE: No
  • Sex: Female
  • Age: 11.20 Year
  • Weight: 29.940 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Unassigned
Reactions Reported:
Urinary incontinence
Outcomes: Ongoing

Dog, ['Shepherd Dog - German', 'Siberian Husky'], Female, 9 year, 34.019 kilogram • Drug: MSK, Unassigned, Oral • Reactions: Difficulty going up/down stairs, Lying down, High leg gait • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-074392
  • Serious AE: No
  • Treated For AE: No
  • Sex: Female
  • Age: 9.00 Year
  • Weight: 34.019 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Unassigned
Reactions Reported:
Difficulty going up/down stairs Lying down High leg gait
Outcomes: Outcome Unknown

Dog, ['Pointer (unspecified)', 'Collie - Border'], Female, 15 year, 22.68 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Anxiety, Vocalisation, Behavioral disorder (unspecified), Diarrhea, Biting -aggression… • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-072884
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 15.00 Year
  • Weight: 22.680 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Unassigned
Reactions Reported:
Anxiety Vocalisation Behavioral disorder (unspecified) Diarrhea Biting -aggression Pacing Frequent urination Inappropriate defecation Inappropriate urination Cognitive disorder NOS Seizure NOS Vocalizing while sleeping Unconscious Nystagmus Difficulty standing Unable to walk Vestibular disorder NOS Limb non-weight bearing Falling Urinary incontinence Medication error NOS Panting Abnormal posture NOS
Outcomes: Outcome Unknown

Dog, ['Collie - Border', 'Dog (unknown)'], Female, 14 year, 20.321 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Tiredness (lethargy), Growling, Biting -aggression, Not himself/herself, Pacing… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-071646
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 14.00 Year
  • Weight: 20.321 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Unassigned
Reactions Reported:
Tiredness (lethargy) Growling Biting -aggression Not himself/herself Pacing Cough Vomiting Regurgitation Weakness Unsteady walking (ataxia) Not eating Elevated alanine aminotransferase Elevated serum alkaline phosphatase Elevated renal parameters Hyperphosphataemia Unable to walk
Outcomes: Ongoing

Dog, ['Retriever (unspecified)', 'Dog (unknown)'], Female, 13 year, 38.555 kilogram • Drug: MSK, Unknown • Reactions: Urinary incontinence • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-070900
  • Serious AE: No
  • Treated For AE: Yes
  • Sex: Female
  • Age: 13.00 Year
  • Weight: 38.555 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Urinary incontinence
Outcomes: Ongoing

Dog, Pointing Dog - German (unspecified), Male, 20 month, 30.391 kilogram • Drug: MSK, Tablet, chewable, Oral, Dose: 1 tablet per dose, Frequency: 1 per day • Reactions: Vomiting, Underdose • Outcome: Recovered/Normal

  • Report ID: CAN-USFDACVM-2025-CA-000112
  • Serious AE: No
  • Treated For AE: No
  • Sex: Male
  • Age: 20.00 Month
  • Weight: 30.391 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet, chewable
  • Dose: 1 tablet per dose
  • Frequency: 1 per day
Reactions Reported:
Vomiting Underdose
Outcomes: Recovered/Normal

Dog, Shepherd (unspecified), Female, 15.42 year, 23.13 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Vaginal haemorrhage, Renal degeneration, Mass NOS, Thrombosis • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-070127
  • Serious AE: No
  • Treated For AE: No
  • Sex: Female
  • Age: 15.42 Year
  • Weight: 23.130 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Unassigned
Reactions Reported:
Vaginal haemorrhage Renal degeneration Mass NOS Thrombosis
Outcomes: Ongoing

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Overdose Information

No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.

Storage & Handling

No approved storage guidance is linked yet for this ingredient. Use manufacturer packaging and veterinary guidance for handling/storage.

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