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Roxee Medication Guide

Prednisolone

Medication reference facts with explicit FDA-approval, off-label, source-limited, and safety context. Roxee does not sell, prescribe, or dispense medications.

Both Reference complete FDA data linked Rx required Tablet Multiple FDA labelers Official label facts Owner quick guide first
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Data freshness

Reference facts
Reference refreshed
Aug 6, 2026, 7:47 p.m.

These are the reference facts Roxee uses on browse cards and quick facts.

FDA applications
FDA application data refreshed
Aug 6, 2026, 7:47 p.m.

Sponsor, product, and application records imported from Animal Drugs @ FDA.

Safety reports
Safety data refreshed
Aug 6, 2026, 7:49 p.m.

openFDA reaction terms and case summaries are supporting evidence, not proof of causality.

Source timing details
Source timing details
  • Reference facts: Source Roxee | Refreshed Aug 6, 2026, 7:47 PM UTC
    The reference fact projection used for browse cards and quick facts.
  • Animal Drugs @ FDA: Source FDA | Refreshed Aug 6, 2026, 7:47 PM UTC
    Applications/products are imported from FDA export data.
  • Animal Drugs @ FDA previews: Source FDA | Refreshed Feb 9, 2026, 3:05 AM UTC
    Label highlights/doc links are fetched from FDA preview endpoints.
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed Aug 6, 2026, 7:47 PM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
  • openFDA reaction terms: Source FDA openFDA | Refreshed Aug 6, 2026, 7:52 PM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Aug 6, 2026, 7:52 PM UTC
Illustration placeholder
Prednisolone

Prednisolone

Drug type: Generic ingredient • Branded profile • FDA branded products available

Both Tablet Rx required 100% reference complete

Species: Both

Manufacturer: Multiple FDA labelers

Medication Snapshot

Merged from the current Roxee medication system with field-level provenance, freshness, and completeness tracking.

Prednisolone

The drug is indicated in the treatment of dogs for conditions requiring an anti-inflammatory agent. The drug is indicated for the treatment of acute musculoskeletal inflammations such as bursitis, carpitis, and spondylitis. The drug is indicated as supportive therapy in nonspecific dermatosis such as summer eczema and atopy. The drug may be used as supportive therapy pre- and post-operatively and for various stress conditions when corticosteroids are required while the animal is being treated for a specific condition. The drug is indicated in the treatment of cats for conditions requiring an anti-inflammatory agent. The drug is indicated for the treatment of acute musculoskeletal inflammations such as bursitis, carpitis, and spondylitis. The drug is indicated as supportive therapy in nonspecific dermatosis such as summer eczema and atopy. The drug may be used as supportive therapy pre- and post-operatively and for various stress conditions when corticosteroids are required while the animal is being treated for a specific condition. The drug is indicated in the treatment of horses for conditions requiring an anti-inflammatory agent. The drug is indicated for the treatment of acute musculoskeletal inflammations such as bursitis, carpitis, and spondylitis. The drug is indicated as supportive therapy in nonspecific dermatosis such as summer eczema and atopy. The drug may be used as supportive therapy pre- and post-operatively and for various stress conditions when corticosteroids are required while the animal is being treated for a specific condition. Species commonly shown: Both, Dog, Restricted During Pregnancy, Dog.

Generic name
Prednisolone
Brand names
PrednisTab®, Meticortelone Acetate, Solu-Delta Cortef® Sterile Powder, Prednisolone Aqueous Suspension
Manufacturer
Multiple FDA labelers
Species
Both, Dog, Horse, Cat
Dosage forms
Tablet, Liquid (Suspension), Liquid, Liquid (Solution)
Prescription
Prescription required
Completeness
100%
Validation
Complete
Brand names
PrednisTab® Meticortelone Acetate Solu-Delta Cortef® Sterile Powder Prednisolone Aqueous Suspension Prednisolone Sodium Succinate for Injection Prednis-A-Vet Injection X Prednisolone Sodium Phosphate PrednisTab Prednisolone Acetate
Dosage forms
Tablet Liquid (Suspension) Liquid Liquid (Solution)

Indications / Uses

The drug is indicated in the treatment of dogs for conditions requiring an anti-inflammatory agent. The drug is indicated for the treatment of acute musculoskeletal inflammations such as bursitis, carpitis, and spondylitis. The drug is indicated as supportive therapy in nonspecific dermatosis such as summer eczema and atopy. The drug may be used as supportive therapy pre- and post-operatively and for various stress conditions when corticosteroids are required while the animal is being treated for a specific condition. The drug is indicated in the treatment of cats for conditions requiring an anti-inflammatory agent. The drug is indicated for the treatment of acute musculoskeletal inflammations such as bursitis, carpitis, and spondylitis. The drug is indicated as supportive therapy in nonspecific dermatosis such as summer eczema and atopy. The drug may be used as supportive therapy pre- and post-operatively and for various stress conditions when corticosteroids are required while the animal is being treated for a specific condition. The drug is indicated in the treatment of horses for conditions requiring an anti-inflammatory agent. The drug is indicated for the treatment of acute musculoskeletal inflammations such as bursitis, carpitis, and spondylitis. The drug is indicated as supportive therapy in nonspecific dermatosis such as summer eczema and atopy. The drug may be used as supportive therapy pre- and post-operatively and for various stress conditions when corticosteroids are required while the animal is being treated for a specific condition.

Warnings / Contraindications

Federal law restricts this drug to use by or on the order of a licensed veterinarian. Not for use in horses intended for food. Federal law restricts this drug to use by or on the order of a licensed veterinarian. Clinical and experimental data have demonstrated that corticosteroids administered orally or parenterally to animals may induce the first stage of parturition when administered late in pregnancy and may precipitate premature parturition followed by dystocia, fetal death, retained placenta, and metritis. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

  • Federal law restricts this drug to use by or on the order of a licensed veterinarian. Not for use in horses intended for food. Federal law restricts this drug to use by or on the order of a licensed veterinarian. Clinical and experimental data have demonstrated that corticosteroids administered orally or parenterally to animals may induce the first stage of parturition when administered late in pregnancy and may precipitate premature parturition followed by dystocia, fetal death, retained placenta, and metritis. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Side Effects

Top reported reactions (openFDA): Loss of hearing, Vomiting, Deafness, Lack of efficacy - NOS, Lethargy (see also Central nervous system depression in 'Neurological'), Diarrhoea.

FAQ

Both, Dog, Restricted During Pregnancy, Dog, Horse, Not For Meat Production, Cat

Yes. Roxee shows this as prescription-only.

Tablet, Liquid (Suspension), Liquid, Liquid (Solution)

Related Conditions

Congestive heart failure Corneal ulcer Dystocia Metritis Shock (hypovolemic, septic, cardiogenic, anaphylactic)

Source Transparency

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Pet Owner Quick Guide

Start here first for the safest next-step summary before the deeper medication detail.

Used for:

It is used in treatment of dogs when a rapid adrenal glucocorticoid and/or anti-inflammatory effect is necessary.

Dosing note:

Exact dosing depends on your pet's species, weight, and health status. Use your veterinarian's instructions for the exact dose and schedule.

What to watch for:

  • Not for use in horses intended for food
  • Clinical and experimental data have demonstrated that corticosteroids administered orally or parenterally to animals may induce the first stage of parturition when administered late in pregnancy and may precipitate premature parturition followed by dystocia, fetal death, retained placenta, and metritis
  • wobbly/unsteady walking (1 reports)
  • Loss of appetite (1 reports)
  • Corneal disorder NOS (1 reports)

When to call the vet:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
  • Facial swelling or hives.
  • Blood in vomit or stool.

Regulatory restrictions are shown in Vet View.

What to tell or ask your vet today:

  • Is this medicine the right fit for my pet’s current symptoms?
  • Which warning signs mean I should call back right away?
  • How should I handle missed doses or refusal to take the medicine?

Next actions

Talk to a Vet / Find a Vet Near You Save to pet meds Share page Review report evidence
Research brief

Medication Research Insights

A source-aware map of what to know, what is uncertain, and what to verify with your veterinarian.

Source Backed Signals

What to know

Evidence-backed context Limited

Roxee has limited cited overview evidence for Prednisolone; use the official documents and your veterinarian's instructions for product-specific decisions.

Source: openFDA case USA-USFDACVM-2026-US-014358
Safety signal coverage Reported signals

32 tracked reaction signals; 32 reported cases; 25 serious reports; 2 species groups. These are reporting and label-derived signals for interpretation with a veterinarian.

Source: openFDA case USA-USFDACVM-2026-US-014358
Interpretation guardrail Not causation

Adverse-event reports help form a watch list, but they do not prove the medication caused the reaction and they are not a risk ranking between medications.

Evidence tension

Stronger signal Label / review

Official labels, package inserts, and reviewed summaries carry more weight than isolated reports.

Source: openFDA case USA-USFDACVM-2026-US-014358
Weaker signal Reported data

Case reports and openFDA terms are useful for pattern awareness, but they are incomplete, can include multiple exposures, and do not estimate an individual pet's probability of harm.

Reaction signal map

Most reported reactions Top terms

Unsteady walking (ataxia) (1 reports), Loss of appetite (1 reports), Corneal disorder NOS (1 reports), Constipation (1 reports), Conjunctival reddening (1 reports)

Body systems represented Signal grouping

Digestive (1), Skin & allergy (3), Neurologic (1), Behavior (3)

Explore supporting adverse reports

Species and breed lens

Species represented in reports Species lens

Cat (17 reports), Dog (15 reports)

Breed metadata in reports Metadata only

Domestic Shorthair (6), Crossbred Canine/dog (1), Shepherd Dog - Australian (1). These are report metadata, not proof that a breed is at higher risk.

What your vet may verify

Fit for this patient Vet check

Verify whether Prednisolone fits the pet's species, current diagnosis, age, weight, organ status, pregnancy/lactation status, and concurrent medications.

Evidence limitations Evidence review

Separate label-backed warnings from adverse-event reports and owner observations before changing the plan.

What to watch next

Watch list Owner-safe

Not for use in horses intended for food, Clinical and experimental data have demonstrated that corticosteroids administered orally or parente, wobbly/unsteady walking, Loss of appetite, Corneal disorder NOS

Call sooner if Escalation

Repeated vomiting or diarrhea. Severe lethargy (hard to wake, very low energy). Collapse or fainting.

Bottom line: Use this Prednisolone brief as a structured watch list and source map, not as a reason to start, stop, or change treatment without your veterinarian.
Vet source depth
  1. openFDA case USA-USFDACVM-2026-US-014358 · adverse_reaction · adverse reactions
  2. Contraindication source · fda_animal_drugs · warnings contraindications
  3. FDA application profile · official_label · quick facts
  4. FDA application profile · official_label · quick facts
  5. Medication usage source · fda_animal_drugs · quick facts
  6. SPL · document · documents
  7. FOI · document · documents
  8. FOI · document · documents

Evidence

Review status / Updated / Sources

Review status: Clinical reviewer not listed

Updated: February 12, 2026, 10:44 PM UTC

Sources:
Safety & side effects

Side effects to monitor:

  • Not for use in horses intended for food
  • Clinical and experimental data have demonstrated that corticosteroids administered orally or parenterally to animals may induce the first stage of parturition when administered late in pregnancy and may precipitate premature parturition followed by dystocia, fetal death, retained placenta, and metritis
  • wobbly/unsteady walking
  • Loss of appetite
  • Corneal disorder NOS

Most reported reactions:

  • Unsteady walking (ataxia) (1 reports)
  • Loss of appetite (1 reports)
  • Corneal disorder NOS (1 reports)
Explore reported case details

Emergency warning signs:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
Talk to a Vet / Find a Vet Near You Start Symptom Intake

Vet Fast Scan

Source-backed clinical checkpoints for quick review.

FDA-labeled species
Cat, Dog, Horse
Indication / use
It is used in treatment of dogs when a rapid adrenal glucocorticoid and/or anti-inflammatory effect is necessary.
Form / route / dose
Form: Liquid, Liquid (Solution), Liquid (Suspension), Tablet
Route: Intra-Articular, Intramuscular, Intravenous, Oral
Confirm product label and patient-specific plan.
Warnings
  • High: Federal law restricts this drug to use by or on the order of a licensed veterinarian. Not for use in horses intended fo…
Adverse-event caveat
openFDA adverse-event cases are reported signals. They are not verified, do not prove causation, and do not estimate a pet's individual risk.
Source docs

Quick Facts

Official label facts first, then secondary summaries. Marketing content is separated below.

Species: Both
Manufacturer: Multiple FDA labelers
Form: Liquid, Liquid (Solution), Liquid (Suspension), Tablet
Identifiers:
ANADA: 200784 NADA: 10312 NADA: 11080 NADA: 11403 NADA: 11437 NADA: 11593 NADA: 11700 NADA: 11703 NADA: 117973 NADA: 12204 NADA: 12437 NADA: 12444 NADA: 135771 NADA: 136212 NADA: 140921 NADA: 141298 NADA: 32322 NADA: 35161 NADA: 45288 NADA: 55005
Source metadata:

Warnings / Contraindications

Federal law restricts this drug to use by or on the order of a licensed veterinarian. Not for use in horses intended for food. Federal law restricts this drug to use by or on the order of a licensed veterinarian. Clinical and experimental data have demonstrated that corticosteroids administered orally or parenterally to animals may induce the first stage of parturition when administered late in pregnancy and may precipitate premature parturition followed by dystocia, fetal death, retained placenta, and metritis. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

  • High: Federal law restricts this drug to use by or on the order of a licensed veterinarian. Not for use in horses intended for food. Federal law restricts this drug to use by or on the order of a licensed veterinarian. Clinical and experimental data have demonstrated that corticosteroids administered orally or parenterally to animals may induce the first stage of parturition when administered late in pregnancy and may precipitate premature parturition followed by dystocia, fetal death, retained placenta, and metritis. Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Source metadata:

Adverse Reactions

Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.

Reported case explorer

Filter stored openFDA reports by pet and report attributes. Counts describe reports in this data set, not risk.

Clear filters
openFDA adverse-event cases are reported signals. They are not verified, do not prove causation, and do not estimate a pet's individual risk.
Stored reports
38
Matching reports
38
Active filters
0
Reset
Drill into common report signals
Lethargy (see also Central nervous system depression in Neurological) (9) Vomiting (8) Anorexia (7) Intentional misuse (6) Other (34) Digestive (18) Neurologic (15) Skin & allergy (10)
Showing up to 50 matching reports.

USA-USFDACVM-2026-US-014482

Received 2026-03-27 · MSK · MSK

Serious
Species
Dog
Breed
Crossbred Canine/dog
Size / weight
25-49 lb (12.247 Kilogram)
Age
1-3 years (3 Year)
Sex
Male Intact
Region
USA
Reactions
Injection site painRestlessnessEmesis (multiple)
Body systems
OtherDigestive
Outcomes
Ongoing

USA-USFDACVM-2026-US-014454

Received 2026-03-26 · MSK · MSK

Non-serious
Species
Cat
Breed
Domestic Shorthair
Size / weight
Under 10 lb (3.992 Kilogram)
Age
8+ years (11 Year)
Sex
Female Unknown
Region
USA
Reactions
Facial pruritusMedication error NOS
Body systems
Skin & allergyOther
Outcomes
Recovered/Normal

USA-USFDACVM-2026-US-014426

Received 2026-03-25 · MSK · MSK

Serious
Species
Cat
Breed
Domestic Shorthair
Size / weight
Under 10 lb (3.27 Kilogram)
Age
8+ years (1 Year)
Sex
Male Neutered
Region
USA
Reactions
AnorexiaIntentional misuseAdipsiaConstipationLethargy (see also Central nervous system depression in Neurological)AtaxiaHiding
Body systems
DigestiveOtherNeurologic
Outcomes
Ongoing

USA-USFDACVM-2026-US-013311

Received 2026-03-19 · MSK · MSK

Serious
Species
Cat
Breed
Domestic Shorthair
Size / weight
10-24 lb (5.44 Kilogram)
Age
8+ years (9 Year)
Sex
Male Neutered
Region
USA
Reactions
PolydipsiaPolyuriaHyperglycaemiaDiabetes mellitusUNPALATABLEProduct defect, product difficult to use/handle (see also 'Drug device difficult to use/handle')Intentional misuseOdor, Abnormal
Body systems
Other
Outcomes
Ongoing

USA-USFDACVM-2026-US-014720

Received 2026-03-17 · MSK · MSK

Non-serious
Species
Cat
Breed
Domestic Shorthair
Size / weight
Under 10 lb (2.5 Kilogram)
Age
8+ years (24 Year)
Sex
Female Neutered
Region
USA
Reactions
Lack of efficacy - NOSApplication site reaction NOS
Body systems
EffectivenessOther
Outcomes
Outcome Unknown

USA-USFDACVM-2026-US-013736

Received 2026-03-17 · MSK · MSK

Serious
Species
Dog
Breed
Shepherd Dog - Australian
Size / weight
Under 10 lb (3.45 Kilogram)
Age
Under 1 year (2 Month)
Sex
Female Intact
Region
USA
Reactions
Lethargy (see also Central nervous system depression in Neurological)VomitingAnorexiaTachycardiaFeverIncreased salivationAbnormal radiograph findingNeurological signs NOSIntentional misuseAgitation
Body systems
NeurologicDigestiveOther
Outcomes
Ongoing

USA-USFDACVM-2026-US-014358

Received 2026-03-16 · MSK · MSK

Serious
Species
Cat
Breed
Domestic Shorthair
Size / weight
10-24 lb (5.37 Kilogram)
Age
1-3 years (2 Year)
Sex
Female Neutered
Region
USA
Reactions
VomitingLethargy (see also Central nervous system depression in Neurological)High pancreatic-specific lipaseDehydrationNeutrophiliaPancreatitis NOSNot eatingLeukocytosis NOSDepressionElevated gamma-glutamyl transferase (GGT)AzotaemiaAnaemia NOSHypoalbuminaemiaAbdominal effusionHyperglycaemiaElevated symmetrical dimethylarginine (SDMA)Elevated blood urea nitrogen (BUN)Elevated creatinineHyponatremiaHypochloraemiaLow serum alkaline phosphatase (ALP)Decreased red blood cell countDecreased haemoglobinProteinuria
Body systems
DigestiveNeurologicOther
Outcomes
Recovered/Normal

USA-USFDACVM-2026-US-013313

Received 2026-03-16 · MSK · MSK

Serious
Species
Cat
Breed
Domestic Shorthair
Size / weight
10-24 lb (6.427 Kilogram)
Age
8+ years (13 Year)
Sex
Female Neutered
Region
USA
Reactions
PruritusSkin lesion NOSSkin scab
Body systems
Skin & allergyOther
Outcomes
Ongoing

USA-USFDACVM-2026-US-012224

Received 2026-03-13 · MSK · MSK

Non-serious
Species
Cat
Breed
Domestic Shorthair
Size / weight
Under 10 lb (3 Kilogram)
Age
8+ years (12.5 Year)
Sex
Female Neutered
Region
USA
Reactions
Tongue disorder NOSTongue ulcerationDroolingUnwellTracheal and laryngeal disorder NOSCrustDecreased appetiteLaryngeal oedemaCoughHead tilt - neurological disorder (see also Head tilt - ear disorder)Swallowing disorder NOSLocal swelling (not application site)Lethargy (see also Central nervous system depression in Neurological)Nasal dischargeMalaiseDehydrationOcular discharge
Body systems
OtherDigestiveNeurologicSkin & allergy
Outcomes
Recovered/Normal

USA-USFDACVM-2026-US-011895

Received 2026-03-11 · MSK · MSK

Serious
Species
Cat
Breed
Domestic Shorthair
Size / weight
Under 10 lb (4.377 Kilogram)
Age
1-3 years (1.5 Year)
Sex
Female Unknown
Region
USA
Reactions
VomitingLocalised pain NOS (see other SOCs for specific pain)Limb non-weight bearingLethargy (see also Central nervous system depression in Neurological)Not eatingHead tremorIncreased respiratory ratePlantigrade postureLimb weaknessProprioception deficitCutaneous emphysemaAbnormal radiograph findingKnuckling
Body systems
DigestiveOtherNeurologic
Outcomes
Ongoing

USA-USFDACVM-2026-US-011296

Received 2026-03-11 · MSK · MSK

Serious
Species
Cat
Breed
Domestic Mediumhair
Size / weight
Under 10 lb (3.629 Kilogram)
Age
8+ years (12 Year)
Sex
Female Unknown
Region
USA
Reactions
Tendon rupturePancreas disorderDeath
Body systems
Other
Outcomes
Died

USA-USFDACVM-2026-US-012693

Received 2026-03-08 · MSK · MSK

Serious
Species
Cat
Breed
Domestic Shorthair
Size / weight
Under 10 lb (3.38 Kilogram)
Age
8+ years (18.5 Year)
Sex
Female Unknown
Region
USA
Reactions
Anaemia NOSThrombocytopeniaIncreased percentage reticulocytes
Body systems
Other
Outcomes
Ongoing

USA-USFDACVM-2026-US-011341

Received 2026-03-05 · MSK · MSK

Non-serious
Species
Cat
Breed
Domestic Shorthair
Size / weight
10-24 lb (4.881 Kilogram)
Age
4-7 years (5 Year)
Sex
Female Unknown
Region
USA
Reactions
VomitingAnorexiaDecreased bowel movementsElevated liver enzymes NOSIntentional misuse
Body systems
DigestiveOther
Outcomes
Ongoing

JPN-USFDACVM-2026-JP-000001

Received 2026-03-04 · MSK · MSK

Serious
Species
Dog
Breed
Chihuahua
Size / weight
Under 10 lb (2.9 Kilogram)
Age
8+ years (11 Year)
Sex
Male Unknown
Region
USA
Reactions
Leukocytosis NOSThrombocytopeniaPlatelet disorder NOSElevated C-reactive protein
Body systems
Other
Outcomes
Recovered/Normal

USA-USFDACVM-2026-US-008713

Received 2026-02-27 · MSK · MSK

Serious
Species
Cat
Breed
Domestic Shorthair
Size / weight
10-24 lb (5.806 Kilogram)
Age
8+ years (12 Year)
Sex
Male Neutered
Region
USA
Reactions
WoundPruritusMedication error NOSLack of efficacy - NOSAlopecia localMoist dermatitisEar infection NOSSkin ulcerHead shake - ear disorderItchy earsAbnormal cytologyEar painEar dischargeLocal erythemaDecreased appetiteExudative skin conditionDiscomfort NOS
Body systems
OtherSkin & allergyEffectivenessDigestive
Outcomes
Ongoing

USA-USFDACVM-2026-US-010698

Received 2026-02-24 · MSK · MSK

Non-serious
Species
Cat
Breed
Domestic Shorthair
Size / weight
10-24 lb (6.427 Kilogram)
Age
8+ years (13 Year)
Sex
Female Neutered
Region
USA
Reactions
PruritusSkin lesion NOSSkin scabLabeled drug-species interactionIntentional misuse
Body systems
Skin & allergyOther
Outcomes
Ongoing

USA-USFDACVM-2026-US-008843

Received 2026-02-24 · MSK · MSK

Serious
Species
Cat
Breed
Domestic Shorthair
Size / weight
Under 10 lb (4.137 Kilogram)
Age
8+ years (14 Year)
Sex
Female Unknown
Region
USA
Reactions
Plantigrade postureLamenessAbnormal radiograph finding
Body systems
Other
Outcomes
Ongoing

USA-USFDACVM-2026-US-007281

Received 2026-02-19 · MSK · MSK

Non-serious
Species
Cat
Breed
Domestic Shorthair
Size / weight
Under 10 lb (3.3 Kilogram)
Age
4-7 years (4 Year)
Sex
Female Intact
Region
USA
Reactions
Lack of efficacy - NOS
Body systems
Effectiveness
Outcomes
Outcome Unknown

USA-USFDACVM-2026-US-008034

Received 2026-02-17 · MSK · MSK

Non-serious
Species
Cat
Breed
Cat (unknown)
Age
8+ years (10.5 Year)
Sex
Unknown Unknown
Region
USA
Reactions
HyperglycaemiaElevated betahydroxybutyrate (BHBA)Elevated fructosamine
Body systems
Other
Outcomes
Ongoing

USA-USFDACVM-2026-US-006237

Received 2026-02-04 · MSK · MSK

Serious
Species
Cat
Breed
Domestic Shorthair
Size / weight
10-24 lb (5.987 Kilogram)
Age
8+ years (13 Year)
Sex
Female Unknown
Region
USA
Reactions
ScratchingNasal congestionSneezingSkin scabSkin inflammation NOSHidingAnorexiaElevated symmetrical dimethylarginine (SDMA)Elevated globulinsProteinuriaThrombocytosisDehydrationLack of efficacy - NOSMedication error NOS
Body systems
OtherDigestiveEffectiveness
Outcomes
Ongoing

USA-USFDACVM-2026-US-004595

Received 2026-01-26 · MSK · MSK

Serious
Species
Dog
Breed
Bulldog - American
Age
4-7 years (5.16 Year)
Sex
Female Neutered
Region
USA
Reactions
Other abnormal test result NOSTooth disorderBumps on skinCyst NOSAllergy NOSLoose stoolCrustLocal erythemaLickingDermal noduleOtitis NOSScratchingSneezingDermatitisBehavioural disorder NOSHair loss NOSNasal dischargeWeight gainSkin disorders NOSAlopecia generalAbnormal cytologyLocalised pain NOS (see other SOCs for specific pain)Salivary stainingAnxietySkin lumpMast cell tumourReddening of the skinSkin lesion NOSLack of efficacy (bacteria) - Ehrlichia
Body systems
OtherBehaviorSkin & allergyDigestiveEffectiveness
Outcomes
Ongoing

USA-USFDACVM-2026-US-001275

Received 2026-01-19 · MSK · MSK

Serious
Species
Cat
Breed
Scottish Fold Longhair
Size / weight
Under 10 lb (3.13 Kilogram)
Age
8+ years (15 Year)
Sex
Female Unknown
Region
USA
Reactions
Decreased appetiteDiarrhoeaVomiting
Body systems
Digestive
Outcomes
Ongoing

USA-USFDACVM-2026-US-003666

Received 2026-01-14 · MSK · MSK

Serious
Species
Cat
Breed
Domestic Shorthair
Size / weight
10-24 lb (4.59 Kilogram)
Age
8+ years (9 Year)
Sex
Male Neutered
Region
USA
Reactions
Pulmonary neoplasmIncreased lung soundsTachypnoeaLaboured breathingWeak pulseCrackles on auscultationDeath by euthanasiaAbnormal ultrasound findingHaemorrhage NOS
Body systems
Other
Outcomes
Euthanized

USA-USFDACVM-2025-US-075004

Received 2025-12-23 · MSK · MSK

Non-serious
Species
Cat
Breed
Domestic Shorthair
Size / weight
10-24 lb (5.09 Kilogram)
Age
8+ years (9.5 Year)
Sex
Male Neutered
Region
USA
Reactions
Application site hair lossApplication site bleedingApplication site reddening
Body systems
Skin & allergyOther
Outcomes
Outcome Unknown

USA-USFDACVM-2025-US-074790

Received 2025-12-19 · MSK · MSK

Non-serious
Species
Dog
Breed
Dog (unknown)
Size / weight
50-99 lb (32.5 Kilogram)
Age
4-7 years (4 Year)
Sex
Male Neutered
Region
USA
Reactions
AnxietyElevated serum alkaline phosphatase (ALP)HypercalcaemiaLack of efficacy - NOSAggressionMental function decreasedWeight gainLow sodium-potassium ratio (Na:K ratio)Low liver enzymes NOSGrowlingBehavioural disorder NOS
Body systems
BehaviorOtherEffectiveness
Outcomes
Ongoing

USA-USFDACVM-2025-US-074916

Received 2025-12-17 · MSK · MSK

Non-serious
Species
Cat
Breed
Domestic Shorthair
Size / weight
10-24 lb (6.03 Kilogram)
Age
8+ years (11 Year)
Sex
Male Neutered
Region
USA
Reactions
TremorShaking
Body systems
NeurologicOther
Outcomes
Outcome Unknown

USA-USFDACVM-2025-US-074908

Received 2025-12-16 · MSK · MSK

Non-serious
Species
Cat
Breed
Domestic Shorthair
Size / weight
10-24 lb (5.67 Kilogram)
Age
8+ years (9 Year)
Sex
Female Neutered
Region
USA
Reactions
Diarrhoea
Body systems
Digestive
Outcomes
Ongoing

USA-USFDACVM-2025-US-074064

Received 2025-12-15 · MSK · MSK

Serious
Species
Dog
Breed
['Bichon Frise', 'Chihuahua']
Size / weight
Under 10 lb (3.493 Kilogram)
Age
8+ years (15 Year)
Sex
Female Unknown
Region
USA
Reactions
Seizure NOSAtaxiaUrinary incontinence
Body systems
NeurologicOther
Outcomes
Ongoing

USA-USFDACVM-2025-US-074897

Received 2025-12-12 · MSK · MSK

Serious
Species
Dog
Breed
['Chihuahua', 'Dog (unknown)']
Size / weight
Under 10 lb (2.26 Kilogram)
Age
Under 1 year (2 Week)
Sex
Female Intact
Region
USA
Reactions
IcterusDeathOther abnormal test result NOSElevated liver enzymes NOSSwollen jointLocalised hair lossSkin lesion NOSConjunctival oedemaCorneal oedemaSkin scabSwollen limbLethargy (see also Central nervous system depression in Neurological)AnorexiaEar infection NOSLocal swelling (not application site)
Body systems
OtherSkin & allergyNeurologicDigestive
Outcomes
Died

USA-USFDACVM-2025-US-073464

Received 2025-12-12 · MSK · MSK

Serious
Species
Dog
Breed
Retriever - Labrador
Size / weight
50-99 lb (37.83 Kilogram)
Age
8+ years (11 Year)
Sex
Male Neutered
Region
USA
Reactions
AnaphylaxisSeizure NOSVomitingCollapse NOS (see also Cardio-vascular and Neurological disorders)Loose bowelCongestion of mucous membraneLow blood pressureDecreased body temperature
Body systems
OtherNeurologicDigestive
Outcomes
Recovered/Normal

USA-USFDACVM-2025-US-073345

Received 2025-12-12 · MSK · MSK

Serious
Species
Cat
Breed
Domestic Shorthair
Size / weight
10-24 lb (7.25 Kilogram)
Age
1-3 years (3.16 Year)
Sex
Male Neutered
Region
USA
Reactions
Seizure NOS
Body systems
Neurologic
Outcomes
Recovered/Normal

USA-USFDACVM-2025-US-072888

Received 2025-12-11 · MSK · MSK

Serious
Species
Cat
Breed
Domestic Longhair
Size / weight
10-24 lb (5.715 Kilogram)
Age
8+ years (14 Year)
Sex
Male Neutered
Region
USA
Reactions
SyncopeCollapse NOS (see also Cardio-vascular and Neurological disorders)AnorexiaHidingLow blood pressureHepatomegalyHepato-biliary disorder NOSIntentional misuse
Body systems
OtherNeurologicDigestive
Outcomes
Ongoing

USA-USFDACVM-2025-US-073890

Received 2025-12-09 · MSK · MSK

Serious
Species
Dog
Size / weight
25-49 lb (17.4 Kilogram)
Age
4-7 years (6.35 Year)
Sex
Female Neutered
Region
USA
Reactions
Eye itchingCorneal ulcerOcular dischargeSquintingHorner's syndromeNasal dischargeSneezingEyelid ptosis - neurologic (see also Drooping eyelid NOS)HyperaemiaConjunctival reddeningThird eyelid protrusionAbnormal Schirmer tear testMiosisSunken eyesCorneal disorder NOSNeurogenic keratoconjunctivitis sicca (KCS)Cloudy eye (for Miosis, Mydriasis, Anisocoria, Nystagmus - see Neurological)
Body systems
Skin & allergyOtherNeurologic
Outcomes
Ongoing

USA-USFDACVM-2025-US-072504

Received 2025-12-04 · MSK · MSK

Serious
Species
Dog
Breed
Terrier - Bull - American Pit
Size / weight
50-99 lb (29.03 Kilogram)
Age
1-3 years (2 Year)
Sex
Male Neutered
Region
USA
Reactions
Otitis externaTrigeminus paralysisVomitingCoughMuscle atrophy (see also Muscle wasting)Elevated serum alkaline phosphatase (ALP)Elevated alanine aminotransferase (ALT)HypersalivationUnusual stool colourErythema (for urticaria see Immune SOC)Elevated gamma-glutamyl transferase (GGT)Elevated total bilirubinAbnormal ultrasound findingHepatic fibrosisHepatitisLethargy (see also Central nervous system depression in Neurological)AngioedemaGeneralised rashDyspnoeaIncreased lung soundsLeucocytosis NOSIcterusAbnormal radiograph findingJaw disorder
Body systems
OtherDigestiveSkin & allergyNeurologic
Outcomes
Ongoing

USA-USFDACVM-2025-US-072451

Received 2025-12-01 · MSK · MSK

Serious
Species
Cat
Breed
Domestic Shorthair
Size / weight
10-24 lb (5.69 Kilogram)
Age
4-7 years (7 Year)
Sex
Male Neutered
Region
USA
Reactions
Lethargy (see also Central nervous system depression in Neurological)AnorexiaElevated total bilirubinElevated gamma-glutamyl transferase (GGT)Elevated serum alkaline phosphatase (ALP)Elevated alanine aminotransferase (ALT)JaundiceEnlarged liverHidingNausea
Body systems
NeurologicDigestiveOther
Outcomes
Ongoing

USA-USFDACVM-2025-US-071120

Received 2025-12-01 · MSK · MSK

Non-serious
Species
Cat
Breed
Maine Coon
Size / weight
10-24 lb (5.942 Kilogram)
Age
8+ years (8 Year)
Sex
Male Unknown
Region
USA
Reactions
Pain NOSLamenessNot eatingFeverHigh pancreatic-specific lipaseLethargy (see also Central nervous system depression in Neurological)VomitingLack of efficacy - NOS
Body systems
OtherNeurologicDigestiveEffectiveness
Outcomes
Recovered/Normal

USA-USFDACVM-2025-US-068142

Received 2025-11-10 · MSK · MSK

Non-serious
Species
Cat
Breed
Domestic Shorthair
Size / weight
10-24 lb (7.6 Kilogram)
Age
8+ years (8 Year)
Sex
Female Neutered
Region
USA
Reactions
Horner's syndrome
Body systems
Other
Outcomes
Ongoing

USA-USFDACVM-2025-US-065825

Received 2025-11-05 · MSK · MSK

Serious
Species
Cat
Breed
Domestic Mediumhair
Size / weight
Under 10 lb (3.719 Kilogram)
Age
8+ years (12 Year)
Sex
Male Neutered
Region
USA
Reactions
Reluctant to moveWobblinessNasal congestionSleepiness - systemic disorderHind limb paralysisThrombosisParalysisDeath by euthanasia
Body systems
Other
Outcomes
Euthanized

Tap or hover a reaction to see what it means in plain language.

Tracked signals
32
Reported cases
32
Serious reports
25
Species represented
2
Grouped by Body System
Digestive (1) · Loss of appetite Skin & allergy (3) · Application site hair loss, Alopecia local, Alopecia general Neurologic (1) · Unsteady walking (ataxia) Behavior (3) · Behavioral disorder (unspecified), Anxiety, Aggression Other (24) · Corneal disorder NOS, Constipation, Conjunctival reddening
Most Reported Reactions
Reaction Body system Cases Species Serious cases
Neurologic 1 Cat 1
Digestive 1 Cat 1
Other 1 Dog 1
Other 1 Cat 1
Other 1 Dog 1
Other 1 Dog 1
Other 1 Dog 1
Other 1 Cat 1

Species coverage: Cat (17) Dog (15)

View detailed reaction table
Reaction Body system Species Seriousness Frequency Reports
Neurologic Cat Serious - 1
Digestive Cat Serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Other Dog Serious - 1
Behavior Dog Non-serious - 1
Other Cat Serious - 1
Other Cat Non-serious - 1
Other Cat Non-serious - 1
Skin & allergy Cat Non-serious - 1
Other Cat Non-serious - 1
Behavior Dog Non-serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Skin & allergy Cat Serious - 1
Skin & allergy Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Behavior Dog Non-serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Source metadata:

Source Documents

The most useful source links appear first; full previews and metadata stay in the veterinary/professional layer.

Use original documents to confirm product-specific warnings, ingredients, and handling details with your veterinarian.

Prednis-A-Vet Injection SPL · SPL PrednisTab® SPL · SPL Meticortelone Acetate SPL · SPL

Full source previews and metadata remain in the veterinary/professional layer.

Owner handouts

0
No owner handouts linked yet.

Official label / PI

0
No official label or package insert links yet.

SPL

17

FOI

4

Prednis-A-Vet Injection

SPL · SPL

Open original
FDA Structured Product Label

Prednis-A-Vet Injection

Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.

Sponsor
Bimeda Animal Health Ltd.
NADA
98288
Status
RX
Form
Liquid (Solution)
Route
Intravenous
Species
Dog
Composition / specifications
Each milliliter contains 20 milligrams of prednisolone sodium phosphate (equivalent to 14.88 milligrams of prednisolone) in sterile aqueous solution.

Dogs

Indication
It is used in treatment of dogs when a rapid adrenal glucocorticoid and/or anti-inflammatory effect is necessary.
Dosage
It is administered intravenously in a dosage of 2 1/2 to 5 milligrams of prednisolone sodium phosphate per pound of body weight, initially for shock and shock-like states, followed by equal maintenance doses at 1-, 3-, 6-, or 10-hour intervals as determined by the condition of the animal. If permanent use is required, oral therapy (tablets) may be substituted. If therapy is to be withdrawn after prolonged use, reduce daily dose gradually over a number of days.
Limitations
Do not use in viral infections. Except in emergency therapy, do not use with tuberculosis, chronic nephritis, Cushing's disease, or peptic ulcers. With infections, use appropriate antibacterial therapy with and for at least 3 days after, discontinuance of use and disappearance of all signs of infection. Clinical and experimental data have demonstrated that corticosteroids administered orally or parenterally to animals may induce the first stage of parturition when administered during the last trimester of pregnancy and may precipitate premature parturition followed by dystocia, fetal death, retained placenta and metritis. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

PrednisTab®

SPL · SPL

Open original
FDA Structured Product Label

PrednisTab®

Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.

Sponsor
Lloyd, Inc.
NADA
140-921
Status
RX
Form
Tablet
Route
Oral
Species
Dog
Composition / specifications
Each tablet contains 5 or 20 milligrams prednisolone.

Dogs

Indication
For use as an anti-inflammatory agent.
Dosage
2.5 milligrams per 10 pounds (4.5 kg) body weight per day.
Limitations
Administer total daily dose orally in equally divided doses 6 to 10 hours apart until response is noted or 7 days have elapsed. When response is attained, dosage should be gradually reduced until maintenance level is achieved. Federal law restricts this drug to use by or on the order of a licensed veterinarian. Clinical and experimental data have demonstrated that corticosteroids administered orally or parenterally to animals may induce the first stage of parturition when administered during the last trimester of pregnancy and may precipitate parturition followed by dystocia, fetal death, retained placenta, and metritis. Do not use in viral infections. Systemic therapy with prednisolone is contraindicated in animals with peptic ulcer, corneal ulcer, and Cushingoid syndrome. The presence of diabetes, osteoporosis, predisposition to thrombophlebitis hypertension, congestive heart failure, renal insufficiency and active tuberculosis necessitates carefully controlled use. Some of the above conditions occur only rarely in dogs but should be kept in mind. Anti-inflammatory action of corticosteroids may mask signs of infection.

Meticortelone Acetate

SPL · SPL

Open original
FDA Structured Product Label

Meticortelone Acetate

Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.

Sponsor
Intervet, Inc.
NADA
10312
Status
RX
Form
Liquid (Suspension)
Route
Intramuscular, Intra-Articular
Species
Dog • Horse • Cat
Composition / specifications
Each milliliter of sterile aqueous suspension contains 25 milligrams of prednisolone acetate.

Dogs

Indication
The drug is indicated in the treatment of dogs for conditions requiring an anti-inflammatory agent. The drug is indicated for the treatment of acute musculoskeletal inflammations such as bursitis, carpitis, and spondylitis. The drug is indicated as supportive therapy in nonspecific dermatosis such as summer eczema and atopy. The drug may be used as supportive therapy pre- and post-operatively and for various stress conditions when corticosteroids are required while the animal is being treated for a specific condition.
Dosage
The drug is administered to dogs intramuscularly at a dosage level of 10 to 50 milligrams. The dosage may be repeated when necessary. If the condition is of a chronic nature, an oral corticosteroid may be given as a maintenance dosage. The drug may be given intra-articularly to dogs at a dosage level of 5 to 25 milligrams. The dose may be repeated when necessary after 7 days for two or three doses.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Cats

Indication
The drug is indicated in the treatment of cats for conditions requiring an anti-inflammatory agent. The drug is indicated for the treatment of acute musculoskeletal inflammations such as bursitis, carpitis, and spondylitis. The drug is indicated as supportive therapy in nonspecific dermatosis such as summer eczema and atopy. The drug may be used as supportive therapy pre- and post-operatively and for various stress conditions when corticosteroids are required while the animal is being treated for a specific condition.
Dosage
The drug is administered to cats intramuscularly at a dosage level of 10 to 50 milligrams. The dosage may be repeated when necessary. If the condition is of a chronic nature, an oral corticosteroid may be given as a maintenance dosage. The drug may be given intra-articularly to cats at a dosage level of 5 to 25 milligrams. The dose may be repeated when necessary after 7 days for two or three doses.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Horses

Indication
The drug is indicated in the treatment of horses for conditions requiring an anti-inflammatory agent. The drug is indicated for the treatment of acute musculoskeletal inflammations such as bursitis, carpitis, and spondylitis. The drug is indicated as supportive therapy in nonspecific dermatosis such as summer eczema and atopy. The drug may be used as supportive therapy pre- and post-operatively and for various stress conditions when corticosteroids are required while the animal is being treated for a specific condition.
Dosage
The drug is administered to horses intra-articularly at a dosage level of 50 to 100 milligrams. The dose may be repeated when necessary. If no response is noted after 3 or 4 days, the possibility must be considered that the condition is unresponsive to prednisolone therapy.
Limitations
Not for use in horses intended for food. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Prednisolone Aqueous Suspension

SPL · SPL

Open original

This source does not expose a safe inline preview. Use the original source link for the full document.

Prednisolone Sodium Succinate for Injection

SPL · SPL

Open original

This source does not expose a safe inline preview. Use the original source link for the full document.

Solu-Delta Cortef® Sterile Powder

SPL · SPL

Open original
FDA Structured Product Label

Solu-Delta Cortef® Sterile Powder

Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.

Sponsor
Zoetis Inc.
NADA
11593
Status
RX
Form
Liquid
Route
Intravenous, Intramuscular
Species
Dog • Horse • Cat
Composition / specifications
Each milliliter of prednisolone sodium succinate injection contains: Prednisolone sodium succinate equivalent in activity to 10, 20, or 50 milligrams of prednisolone.

Horses

Indication
The drug is intended for the treatment of horses.
Dosage
The dosage for horses is 50 to 100 milligrams as an initial dose given intravenously over a period of one-half to 1 minute, or intramuscularly and may be repeated in inflammatory, allergic, or other stress conditions at intervals of 12, 24, or 48 hours, depending upon the size of the animal, the severity of the condition and the response to treatment.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Dogs

Indication
The drug is intended for the treatment of inflammatory, allergic and less severe stress conditions, where immediate effect is not required, in dogs.
Dosage
The drug may be given intramuscularly at 1 to 5 milligrams ranging upward to 30 to 50 milligrams in large breeds of dogs. Dosage may be repeated in 12 to 24 hours and continued for 3 to 5 days if necessary. If permanent corticosteroid effect is required oral therapy with prednisolone tablets may be substituted.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Indication
The drug is intended for treatment of shock in dogs.
Dosage
The drug is administered intravenously at a range of 2.5 to 5 milligrams per pound of body weight as an initial dose followed by maintenance doses at 1, 3, 6, or 10 hour intervals, as determined by the condition of the animal.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Cats

Indication
The drug is intended for the treatment of inflammatory, allergic and less severe stress conditions, where immediate effect is not required, in cats.
Dosage
The drug may be given intramuscularly at 1 to 5 milligrams ranging upward to 30 to 50 milligrams in large breeds of dogs. Dosage may be repeated in 12 to 24 hours and continued for 3 to 5 days if necessary. If permanent corticosteroid effect is required oral therapy with prednisolone tablets may be substituted.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Prednisolone Acetate SPL

SPL · Structured Product Label

Open original
FDA Structured Product Label XML for Prednisolone Acetate. Use the source link for the full official labeling record.

PrednisTab SPL

SPL · Structured Product Label

Open original
FDA Structured Product Label XML for PrednisTab. Use the source link for the full official labeling record.

PrednisTab SPL

SPL · Structured Product Label

Open original
FDA Structured Product Label XML for PrednisTab. Use the source link for the full official labeling record.

PrednisTab SPL

SPL · Structured Product Label

Open original
FDA Structured Product Label XML for PrednisTab. Use the source link for the full official labeling record.

PrednisTab SPL

SPL · Structured Product Label

Open original
FDA Structured Product Label XML for PrednisTab. Use the source link for the full official labeling record.

Prednisolone Sodium Phosphate SPL

SPL · Structured Product Label

Open original
FDA Structured Product Label XML for Prednisolone Sodium Phosphate. Use the source link for the full official labeling record.

X SPL

SPL · Structured Product Label

Open original
FDA Structured Product Label XML for X. Use the source link for the full official labeling record.

Prednisolone Sodium Phosphate SPL

SPL · Structured Product Label

Open original
FDA Structured Product Label XML for Prednisolone Sodium Phosphate. Use the source link for the full official labeling record.

Prednisolone Sodium Phosphate SPL

SPL · Structured Product Label

Open original
FDA Structured Product Label XML for Prednisolone Sodium Phosphate. Use the source link for the full official labeling record.

X SPL

SPL · Structured Product Label

Open original
FDA Structured Product Label XML for X. Use the source link for the full official labeling record.

X SPL

SPL · Structured Product Label

Open original
FDA Structured Product Label XML for X. Use the source link for the full official labeling record.

N140921_Supp_11_20_1997.pdf

FOI · FOI

Open original

UCM478245.pdf

FOI · FOI

Open original

FOI Summary oA 200-784 Approved June 20, 2024.pdf

FOI · FOI summary

Open original

UCM202424.pdf

FOI · FOI summary

Open original
Source metadata:
Veterinary reference (advanced)

Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.

At a Glance

Quick facts and links to official labeling and safety signals.

Data freshness
  • Reference facts: Source Roxee | Refreshed Aug 6, 2026, 7:47 PM UTC
    The reference fact projection used for browse cards and quick facts.
  • Animal Drugs @ FDA: Source FDA | Refreshed Aug 6, 2026, 7:47 PM UTC
    Applications/products are imported from FDA export data.
  • Animal Drugs @ FDA previews: Source FDA | Refreshed Feb 9, 2026, 3:05 AM UTC
    Label highlights/doc links are fetched from FDA preview endpoints.
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed Aug 6, 2026, 7:47 PM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
  • openFDA reaction terms: Source FDA openFDA | Refreshed Aug 6, 2026, 7:52 PM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Aug 6, 2026, 7:52 PM UTC
Official (FDA)
Identity: Generic ingredient • FDA branded products available
Official FDA brands: PrednisTab Prednisolone Acetate Prednisolone Sodium Phosphate X
Manufacturer mapping: Multiple FDA labelers
Case-reported brands (openFDA): MSK
Catalog species: Both • FDA-labeled species: Cat, Dog, Horse
Rx/OTC: RX
Form/route: Liquid, Liquid (Solution), Liquid (Suspension), Tablet • Intra-Articular, Intramuscular, Intravenous, Oral
Applications: NADA 98288 • NADA 140-921 • NADA 10312 • NADA 12444 • NADA 117-973 • NADA 11593
NDC: Packages 11695-4469-1 11695-4470-1 11789-248-10 11789-249-10 50989-163-53 50989-286-52 • Products 11695 11789 50989 57319 62157 73309
Documents: 2 (FOI: 2) • SPL: 6 • Label highlights • Official documents
Safety (openFDA)
Top reactions: Dog 108 • Cat 134 • View
Case summaries: 38 (showing 8) • View
openFDA reports are unverified and do not prove causation.
Explore
Linked using: Fda_Label (0.95), Fda_Label (0.95), Fda_Label (0.95)
Diagnosis Codes
ICD10_CM: E11.9 ICD10_CM: H60.90 ICD10_CM: J20.9
Type 2 diabetes mellitus without complications

Counseling and Monitoring Highlights

Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.

Owner-facing counseling points
  • Federal law restricts this drug to use by or on the order of a licensed veterinarian. Not for use in horses intended for food. Federal law restricts this drug to use by or on the order of a licensed veterinarian. Clinical and experimental data have demonstrated that corticosteroids administered orally or parenterally to animals may induce the first stage of parturition when administered late in pregnancy and may precipitate premature parturition followed by dystocia, fetal death, retained placenta, and metritis. Federal law restricts this drug to use by or on the order of a licensed veterinarian. (Contraindication, High)
Top reaction signals
Unsteady walking (ataxia) (1) Loss of appetite (1) Corneal disorder NOS (1) Constipation (1) Conjunctival reddening (1) Conjunctival oedema (1) Congestion of mucous membrane (1) Collapse NOS (1)

Identifiers & Packages

Normalized identifiers (NDC/NADA/ANADA) and package metadata from regulator listings.

Identifiers
ANADA: 200784 NADA: 10312 NADA: 11080 NADA: 11403 NADA: 11437 NADA: 11593 NADA: 11700 NADA: 11703 NADA: 117973 NADA: 12204 NADA: 12437 NADA: 12444 NADA: 135771 NADA: 136212 NADA: 140921 NADA: 141298 NADA: 32322 NADA: 35161 NADA: 45288 NADA: 55005 NADA: 65090 NADA: 65259 NADA: 91534 NADA: 98288
Package NDC Product NDC Form / Route Status
11695-4469-1 11695 -
11695-4470-1 11695 -
11695-7043-1 11695 -
11695-7043-2 11695 -
11789-248-10 11789 -
11789-249-10 11789 -
50989-163-53 50989 -
50989-286-52 50989 -
54771-1613-1 54771 -
54771-1614-1 54771 -
54771-3547-1 54771 -
54771-8550-1 54771 -
54771-8550-2 54771 -
57319-441-16 57319 -
58198-0813-1 58198 -
58198-0813-2 58198 -
62157-152-01 62157 -
62157-413-01 62157 -
62157-414-01 62157 -
69043-042-10 69043 -

Enriched Documents

Documents are tiered by source trust: Official, Clinical, Manufacturer, Marketing.

  • Prednisolone Acetate SPL • Structured Product Label • Official
    FDA Structured Product Label from the electronic animal drug product listing directory.
  • PrednisTab SPL • Structured Product Label • Official
    FDA Structured Product Label from the electronic animal drug product listing directory.
  • PrednisTab SPL • Structured Product Label • Official
    FDA Structured Product Label from the electronic animal drug product listing directory.
  • PrednisTab SPL • Structured Product Label • Official
    FDA Structured Product Label from the electronic animal drug product listing directory.
  • PrednisTab SPL • Structured Product Label • Official
    FDA Structured Product Label from the electronic animal drug product listing directory.
  • Prednisolone Sodium Phosphate SPL • Structured Product Label • Official
    FDA Structured Product Label from the electronic animal drug product listing directory.
  • X SPL • Structured Product Label • Official
    FDA Structured Product Label from the electronic animal drug product listing directory.
  • Prednisolone Sodium Phosphate SPL • Structured Product Label • Official
    FDA Structured Product Label from the electronic animal drug product listing directory.
  • Prednisolone Sodium Phosphate SPL • Structured Product Label • Official
    FDA Structured Product Label from the electronic animal drug product listing directory.
  • X SPL • Structured Product Label • Official
    FDA Structured Product Label from the electronic animal drug product listing directory.
  • X SPL • Structured Product Label • Official
    FDA Structured Product Label from the electronic animal drug product listing directory.
  • FOI Summary oA 200-784 Approved June 20, 2024.pdf • FOI summary • Official • July 1, 2024
    FDA FOI summary for application 200784
  • UCM478245.pdf • FOI summary • Official • May 17, 2017
    FDA FOI summary for application 140921
  • N140921_Supp_11_20_1997.pdf • FOI summary • Official • May 17, 2017
    FDA FOI summary for application 140921
  • UCM202424.pdf • FOI summary • Official • June 1, 2016
    FDA FOI summary for application 141298

Data Sources & Change Log

Every non-trivial field is expected to include provenance and update timestamps.

Official 134 Clinical 1 Manufacturer 0 Marketing 0
Current Field Facts
  • side_effects: Top reported reactions (openFDA): Loss of hearing, Vomiting, Deafness, Lack of efficacy - NOS, Lethargy (see also Central nervous system depression in 'Neurolo… (Clinical, 2026-04-11)
  • contraindications: Federal law restricts this drug to use by or on the order of a licensed veterinarian. Not for use in horses intended for food. Federal law restricts this drug … (Official, 2026-04-12)
  • contraindications: Federal law restricts this drug to use by or on the order of a licensed veterinarian. Not for use in horses intended for food. Federal law restricts this drug … (Official, 2026-04-11)
  • contraindications: Federal law restricts this drug to use by or on the order of a licensed veterinarian. Not for use in horses intended for food. Federal law restricts this drug … (Official, 2026-02-12)
  • indications: PrednisTab™ is intended for use in dogs. The indications for PrednisTab™ are the same as those for other anti-inflammatory steroids and comprise the various co… (Official, 2026-08-06)
  • indications: PrednisTab™ is intended for use in dogs. The indications for PrednisTab™ are the same as those for other anti-inflammatory steroids and comprise the various co… (Official, 2026-08-05)
  • indications: PrednisTab™ is intended for use in dogs. The indications for PrednisTab™ are the same as those for other anti-inflammatory steroids and comprise the various co… (Official, 2026-08-04)
  • indications: PrednisTab™ is intended for use in dogs. The indications for PrednisTab™ are the same as those for other anti-inflammatory steroids and comprise the various co… (Official, 2026-08-03)
  • indications: PrednisTab™ is intended for use in dogs. The indications for PrednisTab™ are the same as those for other anti-inflammatory steroids and comprise the various co… (Official, 2026-08-02)
  • indications: PrednisTab™ is intended for use in dogs. The indications for PrednisTab™ are the same as those for other anti-inflammatory steroids and comprise the various co… (Official, 2026-08-01)
  • indications: PrednisTab™ is intended for use in dogs. The indications for PrednisTab™ are the same as those for other anti-inflammatory steroids and comprise the various co… (Official, 2026-07-31)
  • indications: PrednisTab™ is intended for use in dogs. The indications for PrednisTab™ are the same as those for other anti-inflammatory steroids and comprise the various co… (Official, 2026-07-30)
  • indications: PrednisTab™ is intended for use in dogs. The indications for PrednisTab™ are the same as those for other anti-inflammatory steroids and comprise the various co… (Official, 2026-07-29)
  • indications: PrednisTab™ is intended for use in dogs. The indications for PrednisTab™ are the same as those for other anti-inflammatory steroids and comprise the various co… (Official, 2026-07-28)
  • indications: PrednisTab™ is intended for use in dogs. The indications for PrednisTab™ are the same as those for other anti-inflammatory steroids and comprise the various co… (Official, 2026-07-27)
  • indications: PrednisTab™ is intended for use in dogs. The indications for PrednisTab™ are the same as those for other anti-inflammatory steroids and comprise the various co… (Official, 2026-07-26)
  • indications: PrednisTab™ is intended for use in dogs. The indications for PrednisTab™ are the same as those for other anti-inflammatory steroids and comprise the various co… (Official, 2026-07-25)
  • indications: PrednisTab™ is intended for use in dogs. The indications for PrednisTab™ are the same as those for other anti-inflammatory steroids and comprise the various co… (Official, 2026-07-25)
  • indications: PrednisTab™ is intended for use in dogs. The indications for PrednisTab™ are the same as those for other anti-inflammatory steroids and comprise the various co… (Official, 2026-07-22)
  • indications: PrednisTab™ is intended for use in dogs. The indications for PrednisTab™ are the same as those for other anti-inflammatory steroids and comprise the various co… (Official, 2026-07-22)
Recent Revisions
  • side_effects updated 2026-04-12 10:05 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-04-12 10:05 by etl_backfill • Backfilled from existing medication fields
  • usage updated 2026-04-12 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-04-11 10:05 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-04-11 10:05 by etl_backfill • Backfilled from existing medication fields
  • usage updated 2026-04-11 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields
  • usage updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields

FDA Products & Applications (Animal Drugs @ FDA)

Official sponsor/proprietary-name/application-status records linked by active ingredient.

Product Sponsor Application Status Published
Prednis-A-Vet Injection
RX
Prednisolone Sodium Phosphate
Liquid (Solution) • Intravenous
Label highlights
Official documents
Bimeda Animal Health Ltd. NADA 98288 Approved Oct 2, 2018
PrednisTab®
RX
Prednisolone
Tablet • Oral
Label highlights
Official documents
Lloyd, Inc. NADA 140-921 Approved May 17, 2017
Meticortelone Acetate
RX
Prednisolone Acetate
Liquid (Suspension) • Intramuscular, Intra-Articular
Label highlights
Official documents
Intervet, Inc. NADA 10312 Approved Jun 1, 2016
Prednisolone Aqueous Suspension
RX
Prednisolone Acetate
Official documents
Akorn, Inc. NADA 12444 W Jun 1, 2016
Prednisolone Sodium Succinate for Injection
RX
Prednisolone Sodium Succinate
Official documents
Watson Laboratories, Inc. NADA 117-973 W Jun 1, 2016
Solu-Delta Cortef® Sterile Powder
RX
Prednisolone Sodium Succinate
Liquid • Intravenous, Intramuscular
Label highlights
Official documents
Zoetis Inc. NADA 11593 Approved Jun 1, 2016

Data source: FDA Animal Drugs @ FDA (public search export).

What It's For (FDA Label Highlights)

Extracted from FDA Animal Drugs @ FDA product labeling. Always confirm details with your veterinarian.

Species: Dog
Composition / specifications
Each milliliter contains 20 milligrams of prednisolone sodium phosphate (equivalent to 14.88 milligrams of prednisolone) in sterile aqueous solution.
Dogs
Indication
It is used in treatment of dogs when a rapid adrenal glucocorticoid and/or anti-inflammatory effect is necessary.
Dosage
It is administered intravenously in a dosage of 2 1/2 to 5 milligrams of prednisolone sodium phosphate per pound of body weight, initially for shock and shock-like states, followed by equal maintenance doses at 1-, 3-, 6-, or 10-hour intervals as determined by the condition of the animal. If permanent use is required, oral therapy (tablets) may be substituted. If therapy is to be withdrawn after prolonged use, reduce daily dose gradually over a number of days.
Limitations
Do not use in viral infections. Except in emergency therapy, do not use with tuberculosis, chronic nephritis, Cushing's disease, or peptic ulcers. With infections, use appropriate antibacterial therapy with and for at least 3 days after, discontinuance of use and disappearance of all signs of infection. Clinical and experimental data have demonstrated that corticosteroids administered orally or parenterally to animals may induce the first stage of parturition when administered during the last trimester of pregnancy and may precipitate premature parturition followed by dystocia, fetal death, retained placenta and metritis. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

FDA page: Open in Animal Drugs @ FDA

Species: Dog
Composition / specifications
Each tablet contains 5 or 20 milligrams prednisolone.
Dogs
Indication
For use as an anti-inflammatory agent.
Dosage
2.5 milligrams per 10 pounds (4.5 kg) body weight per day.
Limitations
Administer total daily dose orally in equally divided doses 6 to 10 hours apart until response is noted or 7 days have elapsed. When response is attained, dosage should be gradually reduced until maintenance level is achieved. Federal law restricts this drug to use by or on the order of a licensed veterinarian. Clinical and experimental data have demonstrated that corticosteroids administered orally or parenterally to animals may induce the first stage of parturition when administered during the last trimester of pregnancy and may precipitate parturition followed by dystocia, fetal death, retained placenta, and metritis. Do not use in viral infections. Systemic therapy with prednisolone is contraindicated in animals with peptic ulcer, corneal ulcer, and Cushingoid syndrome. The presence of diabetes, osteoporosis, predisposition to thrombophlebitis hypertension, congestive heart failure, renal insufficiency and active tuberculosis necessitates carefully controlled use. Some of the above conditions occur only rarely in dogs but should be kept in mind. Anti-inflammatory action of corticosteroids may mask signs of infection.

FDA page: Open in Animal Drugs @ FDA

Species: Dog • Horse • Cat
Composition / specifications
Each milliliter of sterile aqueous suspension contains 25 milligrams of prednisolone acetate.
Dogs
Indication
The drug is indicated in the treatment of dogs for conditions requiring an anti-inflammatory agent. The drug is indicated for the treatment of acute musculoskeletal inflammations such as bursitis, carpitis, and spondylitis. The drug is indicated as supportive therapy in nonspecific dermatosis such as summer eczema and atopy. The drug may be used as supportive therapy pre- and post-operatively and for various stress conditions when corticosteroids are required while the animal is being treated for a specific condition.
Dosage
The drug is administered to dogs intramuscularly at a dosage level of 10 to 50 milligrams. The dosage may be repeated when necessary. If the condition is of a chronic nature, an oral corticosteroid may be given as a maintenance dosage. The drug may be given intra-articularly to dogs at a dosage level of 5 to 25 milligrams. The dose may be repeated when necessary after 7 days for two or three doses.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Cats
Indication
The drug is indicated in the treatment of cats for conditions requiring an anti-inflammatory agent. The drug is indicated for the treatment of acute musculoskeletal inflammations such as bursitis, carpitis, and spondylitis. The drug is indicated as supportive therapy in nonspecific dermatosis such as summer eczema and atopy. The drug may be used as supportive therapy pre- and post-operatively and for various stress conditions when corticosteroids are required while the animal is being treated for a specific condition.
Dosage
The drug is administered to cats intramuscularly at a dosage level of 10 to 50 milligrams. The dosage may be repeated when necessary. If the condition is of a chronic nature, an oral corticosteroid may be given as a maintenance dosage. The drug may be given intra-articularly to cats at a dosage level of 5 to 25 milligrams. The dose may be repeated when necessary after 7 days for two or three doses.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Horses
Indication
The drug is indicated in the treatment of horses for conditions requiring an anti-inflammatory agent. The drug is indicated for the treatment of acute musculoskeletal inflammations such as bursitis, carpitis, and spondylitis. The drug is indicated as supportive therapy in nonspecific dermatosis such as summer eczema and atopy. The drug may be used as supportive therapy pre- and post-operatively and for various stress conditions when corticosteroids are required while the animal is being treated for a specific condition.
Dosage
The drug is administered to horses intra-articularly at a dosage level of 50 to 100 milligrams. The dose may be repeated when necessary. If no response is noted after 3 or 4 days, the possibility must be considered that the condition is unresponsive to prednisolone therapy.
Limitations
Not for use in horses intended for food. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

FDA page: Open in Animal Drugs @ FDA

Species: Dog • Horse • Cat
Composition / specifications
Each milliliter of prednisolone sodium succinate injection contains: Prednisolone sodium succinate equivalent in activity to 10, 20, or 50 milligrams of prednisolone.
Horses
Indication
The drug is intended for the treatment of horses.
Dosage
The dosage for horses is 50 to 100 milligrams as an initial dose given intravenously over a period of one-half to 1 minute, or intramuscularly and may be repeated in inflammatory, allergic, or other stress conditions at intervals of 12, 24, or 48 hours, depending upon the size of the animal, the severity of the condition and the response to treatment.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Dogs
Indication
The drug is intended for the treatment of inflammatory, allergic and less severe stress conditions, where immediate effect is not required, in dogs.
Dosage
The drug may be given intramuscularly at 1 to 5 milligrams ranging upward to 30 to 50 milligrams in large breeds of dogs. Dosage may be repeated in 12 to 24 hours and continued for 3 to 5 days if necessary. If permanent corticosteroid effect is required oral therapy with prednisolone tablets may be substituted.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Indication
The drug is intended for treatment of shock in dogs.
Dosage
The drug is administered intravenously at a range of 2.5 to 5 milligrams per pound of body weight as an initial dose followed by maintenance doses at 1, 3, 6, or 10 hour intervals, as determined by the condition of the animal.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Cats
Indication
The drug is intended for the treatment of inflammatory, allergic and less severe stress conditions, where immediate effect is not required, in cats.
Dosage
The drug may be given intramuscularly at 1 to 5 milligrams ranging upward to 30 to 50 milligrams in large breeds of dogs. Dosage may be repeated in 12 to 24 hours and continued for 3 to 5 days if necessary. If permanent corticosteroid effect is required oral therapy with prednisolone tablets may be substituted.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian.

FDA page: Open in Animal Drugs @ FDA

Usage

The drug is indicated in the treatment of dogs for conditions requiring an anti-inflammatory agent. The drug is indicated for the treatment of acute musculoskeletal inflammations such as bursitis, carpitis, and spondylitis. The drug is indicated as supportive therapy in nonspecific dermatosis such as summer eczema and atopy. The drug may be used as supportive therapy pre- and post-operatively and for various stress conditions when corticosteroids are required while the animal is being treated for a specific condition. The drug is indicated in the treatment of cats for conditions requiring an anti-inflammatory agent. The drug is indicated for the treatment of acute musculoskeletal inflammations such as bursitis, carpitis, and spondylitis. The drug is indicated as supportive therapy in nonspecific dermatosis such as summer eczema and atopy. The drug may be used as supportive therapy pre- and post-operatively and for various stress conditions when corticosteroids are required while the animal is being treated for a specific condition. The drug is indicated in the treatment of horses for conditions requiring an anti-inflammatory agent. The drug is indicated for the treatment of acute musculoskeletal inflammations such as bursitis, carpitis, and spondylitis. The drug is indicated as supportive therapy in nonspecific dermatosis such as summer eczema and atopy. The drug may be used as supportive therapy pre- and post-operatively and for various stress conditions when corticosteroids are required while the animal is being treated for a specific condition.

Source: FDA Animal Drugs @ FDA • Reference

Contraindications

Federal law restricts this drug to use by or on the order of a licensed veterinarian. Not for use in horses intended for food. Federal law restricts this drug to use by or on the order of a licensed veterinarian. Clinical and experimental data have demonstrated that corticosteroids administered orally or parenterally to animals may induce the first stage of parturition when administered late in pregnancy and may precipitate premature parturition followed by dystocia, fetal death, retained placenta, and metritis. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Top Reported Reactions (openFDA)

De-duplicated reaction terms grouped by body system from FDA openFDA reports (not verified; does not prove causation).

Digestive
Loss of appetite (1) • Cat

Showing top 5 for Digestive.

Skin & allergy
Application site hair loss (1) • Cat Alopecia local (1) • Cat Alopecia general (1) • Dog

Showing top 5 for Skin & allergy.

Neurologic
Unsteady walking (1) • Cat

Showing top 5 for Neurologic.

Behavior
Behavioral disorder (1) • Dog Anxiety (1) • Dog Aggression (1) • Dog

Showing top 5 for Behavior.

Other
Corneal disorder NOS (1) • Dog Constipation (1) • Cat Conjunctival reddening (1) • Dog Conjunctival oedema (1) • Dog Congestion of mucous membrane (1) • Dog
Show more (19)
Collapse NOS (1) • Cat Cloudy eye (1) • Dog Cardiac arrest (1) • Cat Bumps on skin (1) • Dog Azotaemia (1) • Cat Application site reddening (1) • Cat Application site reaction NOS (1) • Cat Application site bleeding (1) • Cat Angioedema (1) • Dog Anaphylaxis (1) • Dog Anaemia NOS (1) • Cat Allergy NOS (1) • Dog Agitation (1) • Dog Adipsia (1) • Cat Abnormal ultrasound finding (1) • Cat Abnormal Schirmer tear test (1) • Dog Abnormal radiograph finding (1) • Cat Abnormal cytology (1) • Cat Abdominal effusion (1) • Cat

Showing top 5 for Other.

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Adverse Event Case Summaries (openFDA)

These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.

Dog, Crossbred Canine/dog, Male, 3 year, 12.247 kilogram • Drug: MSK, Unassigned, Oral • Reactions: Injection site pain, Restlessness, Vomiting • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2026-US-014482
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 3.00 Year
  • Weight: 12.247 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Unassigned
Reactions Reported:
Injection site pain Restlessness Vomiting
Outcomes: Ongoing

Cat, Domestic Shorthair, Female, 11 year, 3.992 kilogram • Drug: MSK, Unassigned, Oral, Frequency: 1 per day • Reactions: Facial pruritus, Medication error NOS • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2026-US-014454
  • Serious AE: No
  • Treated For AE: No
  • Sex: Female
  • Age: 11.00 Year
  • Weight: 3.992 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Unassigned
  • Frequency: 1 per day
Reactions Reported:
Facial pruritus Medication error NOS
Outcomes: Recovered/Normal

Cat, Domestic Shorthair, Male, 10 year, 3.27 kilogram • Drug: MSK, Unassigned, Oral • Reactions: Loss of appetite, Intentional misuse, Adipsia, Constipation, Tiredness (lethargy)… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2026-US-014426
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 10.00 Year
  • Weight: 3.270 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Unassigned
Reactions Reported:
Loss of appetite Intentional misuse Adipsia Constipation Tiredness (lethargy) Unsteady walking (ataxia) Hiding
Outcomes: Ongoing

Cat, Domestic Shorthair, Male, 9 year, 5.44 kilogram • Drug: MSK, Oral, Dose: 2 Milligram per kilogram, Frequency: 12 per hour • Reactions: Polydipsia, Polyuria, Hyperglycaemia, Diabetes mellitus, UNPALATABLE… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2026-US-013311
  • Serious AE: Yes
  • Treated For AE: No
  • Sex: Male
  • Age: 9.00 Year
  • Weight: 5.440 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Dose: 2 Milligram per kilogram
  • Frequency: 12 per hour
Reactions Reported:
Polydipsia Polyuria Hyperglycaemia Diabetes mellitus UNPALATABLE Product defect, product difficult to use/handle Intentional misuse Odor, Abnormal
Outcomes: Ongoing

Cat, Domestic Shorthair, Female, 24 year, 2.5 kilogram • Drug: MSK, Transdermal • Reactions: Lack of efficacy - NOS, Application site reaction NOS • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2026-US-014720
  • Serious AE: No
  • Treated For AE: No
  • Sex: Female
  • Age: 24.00 Year
  • Weight: 2.500 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Transdermal
Reactions Reported:
Lack of efficacy - NOS Application site reaction NOS
Outcomes: Outcome Unknown

Dog, Shepherd Dog - Australian, Female, 2 month, 3.45 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Tiredness (lethargy), Vomiting, Loss of appetite, Tachycardia, Fever… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2026-US-013736
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 2.00 Month
  • Weight: 3.450 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Unassigned
Reactions Reported:
Tiredness (lethargy) Vomiting Loss of appetite Tachycardia Fever Increased salivation Abnormal radiograph finding Neurological signs NOS Intentional misuse Agitation
Outcomes: Ongoing

Cat, Domestic Shorthair, Female, 2 year, 5.37 kilogram • Drug: MSK, Unknown, Dose: 0.60 mL per animal, Frequency: 48 per hour • Reactions: Vomiting, Tiredness (lethargy), High pancreatic-specific lipase, Dehydration, Neutrophilia… • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2026-US-014358
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 2.00 Year
  • Weight: 5.370 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Dose: 0.60 mL per animal
  • Frequency: 48 per hour
Reactions Reported:
Vomiting Tiredness (lethargy) High pancreatic-specific lipase Dehydration Neutrophilia Pancreatitis NOS Not eating Leukocytosis NOS Depression Elevated gamma-glutamyl transferase Azotaemia Anaemia NOS Hypoalbuminaemia Abdominal effusion Hyperglycaemia Elevated symmetrical dimethylarginine Elevated blood urea nitrogen Elevated creatinine Hyponatremia Hypochloraemia Low serum alkaline phosphatase Decreased red blood cell count Decreased haemoglobin Proteinuria
Outcomes: Recovered/Normal

Cat, Domestic Shorthair, Female, 13 year, 6.427 kilogram • Drug: MSK, Unknown • Reactions: Itching, Skin lesion NOS, Skin scab • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2026-US-013313
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 13.00 Year
  • Weight: 6.427 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Itching Skin lesion NOS Skin scab
Outcomes: Ongoing

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Overdose Information

No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.

Storage & Handling

No approved storage guidance is linked yet for this ingredient. Use manufacturer packaging and veterinary guidance for handling/storage.

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