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Roxee Meds Catalog

Progesterone

Medication catalog facts with explicit FDA-approval, off-label, source-limited, and safety context.

Both Catalog complete Livestock/food-animal use Non-Rx Insert Multiple FDA labelers Official label facts Owner quick guide first
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Storefront facts
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Sponsor, product, and application records imported from Animal Drugs @ FDA.

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openFDA reaction terms and case summaries are supporting evidence, not proof of causality.

Source timing details
Source timing details
  • Storefront facts: Source Roxee | Refreshed May 5, 2026, 10:05 AM UTC
    The storefront fact projection used for browse cards and quick facts.
  • Animal Drugs @ FDA: Source FDA | Refreshed May 5, 2026, 10:00 AM UTC
    Applications/products are imported from FDA export data.
  • Animal Drugs @ FDA previews: Source FDA | Refreshed Feb 9, 2026, 3:05 AM UTC
    Label highlights/doc links are fetched from FDA preview endpoints.
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed May 5, 2026, 10:00 AM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).

Evidence

Reviewed / Updated / Sources

Reviewed by: Not available

Last reviewed: February 12, 2026

Updated: February 12, 2026, 10:44 PM UTC

Sources:
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Progesterone

Progesterone

Drug type: Food-animal record • Branded profile • Livestock/food-animal use

Both Insert Non-Rx 100% storefront ready

Species: Both

Approval status: Food-animal or livestock record. This source record is for livestock or food-animal use, not a dog/cat medication profile. Food-animal rules, withdrawal intervals, and residue restrictions may apply.

Medication Snapshot

Merged from the current Roxee medication system with field-level provenance, freshness, and completeness tracking.

Progesterone

For increased rate of weight gain in growing beef steers fed in confinement for slaughter in a reimplantation program where SYNOVEX® C or SYNOVEX® S is the first implant and a SYNOVEX® S implant is administered approximately 70 days later. Other than ad described on labeling, this implant is not approved for repeated implantation (reimplantation) with any other cattle ear implant in growing beef steers fed in confinement for slaughter as safety and effectiveness have not been evaluated. Do not use in beef calves less than 2 months of age, dairy calves, and veal calves because effectiveness and safety have not been evaluated. Do not use in animals intended for subsequent breeding, or in dairy cows. For increased rate of weight gain in growing beef steers fed in confinement for slaughter in a reimplantation program where SYNOVEX® C or SYNOVEX® S is the first implant and a SYNOVEX® S implant is administered approximately 70 days later. Other than as described on labeling, this implant is not approved for repeated implantation (reimplantation) with any other cattle ear implant in growing beef steers fed in confinement for slaughter as safety and effectiveness have not been evaluated. Do not use in beef calves less than 2 months of age, dairy calves, and veal calves because effectiveness and safety have not been evaluated. Do not use in animals intended for subsequent breeding, or in dairy cows. For increased rate of weight gain in beef calves 45 days of age and older and weighing up to 400 lbs. This implant is not approved for repeated implantation (reimplantation) with this or any other cattle ear implant as safety and effectiveness has not been evaluated. Species commonly shown: Both, Beef cows and beef heifers (female breeding stock), Dairy cows and heifers (female breeding stock).

Generic name
Progesterone
Brand names
EAZI-BREED™ CIDR® Cattle Insert, EAZI-BREED™ CIDR® Sheep Insert, AX Pharmaceutical Corp, EAZI-BREED CIDR Cattle Insert
Manufacturer
Multiple FDA labelers
Species
Both, Beef cows and beef heifers (female breeding stock), Dairy cows and heifers (female breeding stock), Sheep, Breeding
Dosage forms
Insert, Solid Matrix
Prescription
Non-prescription
Completeness
100%
Validation
Complete
Brand names
EAZI-BREED™ CIDR® Cattle Insert EAZI-BREED™ CIDR® Sheep Insert AX Pharmaceutical Corp EAZI-BREED CIDR Cattle Insert EAZI-BREED CIDR Sheep Insert Progesterone
Dosage forms
Insert Solid Matrix

Indications / Uses

For increased rate of weight gain in growing beef steers fed in confinement for slaughter in a reimplantation program where SYNOVEX® C or SYNOVEX® S is the first implant and a SYNOVEX® S implant is administered approximately 70 days later. Other than ad described on labeling, this implant is not approved for repeated implantation (reimplantation) with any other cattle ear implant in growing beef steers fed in confinement for slaughter as safety and effectiveness have not been evaluated. Do not use in beef calves less than 2 months of age, dairy calves, and veal calves because effectiveness and safety have not been evaluated. Do not use in animals intended for subsequent breeding, or in dairy cows. For increased rate of weight gain in growing beef steers fed in confinement for slaughter in a reimplantation program where SYNOVEX® C or SYNOVEX® S is the first implant and a SYNOVEX® S implant is administered approximately 70 days later. Other than as described on labeling, this implant is not approved for repeated implantation (reimplantation) with any other cattle ear implant in growing beef steers fed in confinement for slaughter as safety and effectiveness have not been evaluated. Do not use in beef calves less than 2 months of age, dairy calves, and veal calves because effectiveness and safety have not been evaluated. Do not use in animals intended for subsequent breeding, or in dairy cows. For increased rate of weight gain in beef calves 45 days of age and older and weighing up to 400 lbs. This implant is not approved for repeated implantation (reimplantation) with this or any other cattle ear implant as safety and effectiveness has not been evaluated.

Warnings / Contraindications

For use in suckling beef calves (at least 45 days of age) up to 400 pounds of body weight. For subcutaneous ear implantation, one dose per animal. Do not use in bull calves intended for reproduction. Safety and effectiveness have not been established in veal calves. A withdrawal period has not been established for this product in preruminating calves. Do not use in calves to be processed for veal. This product is approved for concurrent use of dinoprost solution on day 7 of the 7-day administration period when used for the following indications: For synchronization of estrus in lactating dairy cows. Do not use in animals with abnormal, immature, or infected genital tracts; or in dairy cows that are fewer than 40 days postpartum for synchronization of estrus or synchronization of the return to estrus; or in anestrous lactating dairy cows less than 42 days or greater than 78 days postpartum for induction of estrous cycles. Do not use an insert more than once. To prevent the potential transmission of venereal and blood borne diseases, the inserts should be disposed after a single use. Administration of vaginal inserts for periods greater than 7 days may result in reduced fertility. Product labeling shall bear the following warnings: "Avoid contact with skin by wearing protective gloves when handling inserts. Store used (removed) inserts in a plastic bag or other sealable container until they can be properly disposed in accordance with applicable local, State, and Federal regulations. Do not use in animals with abnormal, immature, or infected genital tracts; or in dairy cows that are fewer than 40 days postpartum for synchronization of estrus or synchronization of the return to estrus; or in anestrous lactating dairy cows less than 42 days or greater than 78 days postpartum for induction of estrous cycles. Do not use an insert more than once. To prevent the potential transmission of venereal and blood borne diseases, the inserts should be disposed after a single use. Administration of vaginal inserts for periods greater than 7 days may result in reduced fertility Product labeling shall bear the following warnings: "Avoid contact with skin by wearing protective gloves when handling inserts. Store used (removed) inserts in a plastic bag or other sealable container until they can be properly disposed in accordance with applicable local, State, and Federal regulations..

  • For use in suckling beef calves (at least 45 days of age) up to 400 pounds of body weight. For subcutaneous ear implantation, one dose per animal. Do not use in bull calves intended for reproduction. Safety and effectiveness have not been established in veal calves. A withdrawal period has not been established for this product in preruminating calves. Do not use in calves to be processed for veal. This product is approved for concurrent use of dinoprost solution on day 7 of the 7-day administration period when used for the following indications: For synchronization of estrus in lactating dairy cows. Do not use in animals with abnormal, immature, or infected genital tracts; or in dairy cows that are fewer than 40 days postpartum for synchronization of estrus or synchronization of the return to estrus; or in anestrous lactating dairy cows less than 42 days or greater than 78 days postpartum for induction of estrous cycles. Do not use an insert more than once. To prevent the potential transmission of venereal and blood borne diseases, the inserts should be disposed after a single use. Administration of vaginal inserts for periods greater than 7 days may result in reduced fertility. Product labeling shall bear the following warnings: "Avoid contact with skin by wearing protective gloves when handling inserts. Store used (removed) inserts in a plastic bag or other sealable container until they can be properly disposed in accordance with applicable local, State, and Federal regulations. Do not use in animals with abnormal, immature, or infected genital tracts; or in dairy cows that are fewer than 40 days postpartum for synchronization of estrus or synchronization of the return to estrus; or in anestrous lactating dairy cows less than 42 days or greater than 78 days postpartum for induction of estrous cycles. Do not use an insert more than once. To prevent the potential transmission of venereal and blood borne diseases, the inserts should be disposed after a single use. Administration of vaginal inserts for periods greater than 7 days may result in reduced fertility Product labeling shall bear the following warnings: "Avoid contact with skin by wearing protective gloves when handling inserts. Store used (removed) inserts in a plastic bag or other sealable container until they can be properly disposed in accordance with applicable local, State, and Federal regulations..

Side Effects

Top reported reactions (openFDA): Behavioural disorder NOS.

FAQ

Both, Beef cows and beef heifers (female breeding stock), Dairy cows and heifers (female breeding stock), Sheep, Breeding

No. Roxee does not currently show this as prescription-only.

Insert, Solid Matrix

Source Transparency

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Pet Owner Quick Guide

Start here first for the safest next-step summary before the deeper medication detail.

Used for:

For synchronization of estrus in lactating dairy cows.

Dosing note:

Exact dosing depends on your pet's species, weight, and health status. Use your veterinarian's instructions for the exact dose and schedule.

What to watch for:

  • For use in suckling beef calves (at least 45 days of age) up to 400 pounds of body weight
  • For subcutaneous ear implantation, one dose per animal
  • Do not use in bull calves intended for reproduction
  • Safety and effectiveness have not been established in veal calves
  • A withdrawal period has not been established for this product in preruminating calves
  • Do not use in calves to be processed for veal
  • This product is approved for concurrent use of dinoprost solution on day 7 of the 7-day administration period when used for the following indications: For synchronization of estrus in lactating dairy cows
  • Do not use in animals with abnormal, immature, or infected genital tracts
  • or in dairy cows that are fewer than 40 days postpartum for synchronization of estrus or synchronization of the return to estrus
  • or in anestrous lactating dairy cows less than 42 days or greater than 78 days postpartum for induction of estrous cycles
  • Do not use an insert more than once
  • To prevent the potential transmission of venereal and blood borne diseases, the inserts should be disposed after a single use
  • Administration of vaginal inserts for periods greater than 7 days may result in reduced fertility
  • Product labeling shall bear the following warnings: "Avoid contact with skin by wearing protective gloves when handling inserts
  • Store used (removed) inserts in a plastic bag or other sealable container until they can be properly disposed in accordance with applicable local, State, and Federal regulations
  • Administration of vaginal inserts for periods greater than 7 days may result in reduced fertility Product labeling shall bear the following warnings: "Avoid contact with skin by wearing protective gloves when handling inserts
  • Behavioral disorder (1 reports)

When to call the vet:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
  • Facial swelling or hives.
  • Blood in vomit or stool.

What to tell or ask your vet today:

  • Is this medicine the right fit for my pet’s current symptoms?
  • Which warning signs mean I should call back right away?
  • How should I handle missed doses or refusal to take the medicine?
Major cautions & emergency warning signs

Side effects to monitor:

  • For use in suckling beef calves (at least 45 days of age) up to 400 pounds of body weight
  • For subcutaneous ear implantation, one dose per animal
  • Do not use in bull calves intended for reproduction
  • Safety and effectiveness have not been established in veal calves
  • A withdrawal period has not been established for this product in preruminating calves

Most reported reactions:

  • Behavioral disorder (unspecified) (1 reports)

Emergency warning signs:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
Talk to a Vet / Find a Vet Near You Start Symptom Intake

Quick Facts

Official label facts first, then secondary summaries. Marketing content is separated below.

Species: Both
Manufacturer: Multiple FDA labelers
Form: Insert, Solid Matrix
Identifiers:
NADA: 110315 NADA: 141200 NADA: 141302 NADA: 9576 NDC Package: 54771-1533-1 NDC Package: 54771-3902-1 NDC Package: 54771-3903-1 NDC Package: 54771-3903-2 NDC Package: 54771-5207-1 NDC Package: 58198-0507-2 NDC Package: 58198-0792-1 NDC Package: 62157-485-01 NDC Package: 73309-381-01 NDC Package: 73377-133-01 NDC Package: 73377-160-01 NDC Package: 73377-160-02 NDC Package: 73377-160-03 NDC Package: 77382-0200-1 NDC Product: 54771 NDC Product: 58198
Source metadata:

Warnings / Contraindications

For use in suckling beef calves (at least 45 days of age) up to 400 pounds of body weight. For subcutaneous ear implantation, one dose per animal. Do not use in bull calves intended for reproduction. Safety and effectiveness have not been established in veal calves. A withdrawal period has not been established for this product in preruminating calves. Do not use in calves to be processed for veal. This product is approved for concurrent use of dinoprost solution on day 7 of the 7-day administration period when used for the following indications: For synchronization of estrus in lactating dairy cows. Do not use in animals with abnormal, immature, or infected genital tracts; or in dairy cows that are fewer than 40 days postpartum for synchronization of estrus or synchronization of the return to estrus; or in anestrous lactating dairy cows less than 42 days or greater than 78 days postpartum for induction of estrous cycles. Do not use an insert more than once. To prevent the potential transmission of venereal and blood borne diseases, the inserts should be disposed after a single use. Administration of vaginal inserts for periods greater than 7 days may result in reduced fertility. Product labeling shall bear the following warnings: "Avoid contact with skin by wearing protective gloves when handling inserts. Store used (removed) inserts in a plastic bag or other sealable container until they can be properly disposed in accordance with applicable local, State, and Federal regulations. Do not use in animals with abnormal, immature, or infected genital tracts; or in dairy cows that are fewer than 40 days postpartum for synchronization of estrus or synchronization of the return to estrus; or in anestrous lactating dairy cows less than 42 days or greater than 78 days postpartum for induction of estrous cycles. Do not use an insert more than once. To prevent the potential transmission of venereal and blood borne diseases, the inserts should be disposed after a single use. Administration of vaginal inserts for periods greater than 7 days may result in reduced fertility Product labeling shall bear the following warnings: "Avoid contact with skin by wearing protective gloves when handling inserts. Store used (removed) inserts in a plastic bag or other sealable container until they can be properly disposed in accordance with applicable local, State, and Federal regulations..

  • High: For use in suckling beef calves (at least 45 days of age) up to 400 pounds of body weight. For subcutaneous ear implantation, one dose per animal. Do not use in bull calves intended for reproduction. Safety and effectiveness have not been established in veal calves. A withdrawal period has not been established for this product in preruminating calves. Do not use in calves to be processed for veal. This product is approved for concurrent use of dinoprost solution on day 7 of the 7-day administration period when used for the following indications: For synchronization of estrus in lactating dairy cows. Do not use in animals with abnormal, immature, or infected genital tracts; or in dairy cows that are fewer than 40 days postpartum for synchronization of estrus or synchronization of the return to estrus; or in anestrous lactating dairy cows less than 42 days or greater than 78 days postpartum for induction of estrous cycles. Do not use an insert more than once. To prevent the potential transmission of venereal and blood borne diseases, the inserts should be disposed after a single use. Administration of vaginal inserts for periods greater than 7 days may result in reduced fertility. Product labeling shall bear the following warnings: "Avoid contact with skin by wearing protective gloves when handling inserts. Store used (removed) inserts in a plastic bag or other sealable container until they can be properly disposed in accordance with applicable local, State, and Federal regulations. Do not use in animals with abnormal, immature, or infected genital tracts; or in dairy cows that are fewer than 40 days postpartum for synchronization of estrus or synchronization of the return to estrus; or in anestrous lactating dairy cows less than 42 days or greater than 78 days postpartum for induction of estrous cycles. Do not use an insert more than once. To prevent the potential transmission of venereal and blood borne diseases, the inserts should be disposed after a single use. Administration of vaginal inserts for periods greater than 7 days may result in reduced fertility Product labeling shall bear the following warnings: "Avoid contact with skin by wearing protective gloves when handling inserts. Store used (removed) inserts in a plastic bag or other sealable container until they can be properly disposed in accordance with applicable local, State, and Federal regulations..
Source metadata:

Adverse Reactions

Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.

Tap or hover a reaction to see what it means in plain language.

Tracked signals
1
Reported cases
1
Serious reports
0
Species represented
1
Grouped by Body System
Behavior (1) · Behavioral disorder (unspecified)
Most Reported Reactions
Reaction Body system Cases Species Serious cases
Behavior 1 Dog 0

Species coverage: Dog (1)

View detailed reaction table
Reaction Body system Species Seriousness Frequency Reports
Behavior Dog Non-serious - 1
Source metadata:

Documents

Owner handouts and official technical documents open on-page first, with the original source still one click away.

Owner handouts

0
No owner handouts linked yet.

Official label / PI

6

SPL

6

FOI

12

141-200

Official label / PI · EA

Open original

141-200

Official label / PI · FONSI

Open original

141-200

Official label / PI · EA

Open original

141-200

Official label / PI · FONSI

Open original

141-200

Official label / PI · EA

Open original

141-200

Official label / PI · FONSI

Open original

EAZI-BREED™ CIDR® Cattle Insert

SPL · SPL

Open original
FDA Structured Product Label

EAZI-BREED™ CIDR® Cattle Insert

Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.

Sponsor
Zoetis Inc.
NADA
141-200
Status
OTC
Form
Insert
Route
Intravaginal
Species
Beef cows and beef heifers (female breeding stock) • Dairy cows and heifers (female breeding stock)
Composition / specifications
Each insert contains 1.38 grams of progesterone in molded silicone over a nylon spine.

Lactating Dairy Cows

Indication
For synchronization of estrus in lactating dairy cows.
Dosage
Administer one intravaginal insert per animal for 7 days. Administer 25 milligrams dinoprost (5 milliliters of 5 milligrams per milliliter solution) as a single intramuscular injection insert removal, on Day 7 of the 7 day administration period.
Limitations
This product is approved for concurrent use of dinoprost solution on day 7 of the 7-day administration period when used for the following indications:  For synchronization of estrus in lactating dairy cows. Do not use in animals with abnormal, immature, or infected genital tracts; or in dairy cows that are fewer than 40 days postpartum for synchronization of estrus or synchronization of the return to estrus; or in anestrous lactating dairy cows less than 42 days or greater than 78 days postpartum for induction of estrous cycles. Do not use an insert more than once. To prevent the potential transmission of venereal and blood borne diseases, the inserts should be disposed after a single use. Administration of vaginal inserts for periods greater than 7 days may result in reduced fertility. Product labeling shall bear the following warnings: "Avoid contact with skin by wearing protective gloves when handling inserts. Store used (removed) inserts in a plastic bag or other sealable container until they can be properly disposed in accordance with applicable local, State, and Federal regulations.
Indication
For induction of estrous cycles in anestrous lactating dairy cows.
Dosage
Administer one intravaginal insert per anestrous cow and remove 7 days later.
Limitations
Do not use in animals with abnormal, immature, or infected genital tracts; or in dairy cows that are fewer than 40 days postpartum for synchronization of estrus or synchronization of the return to estrus; or in anestrous lactating dairy cows less than 42 days or greater than 78 days postpartum for induction of estrous cycles. Do not use an insert more than once. To prevent the potential transmission of venereal and blood borne diseases, the inserts should be disposed after a single use. Administration of vaginal inserts for periods greater than 7 days may result in reduced fertility Product labeling shall bear the following warnings: "Avoid contact with skin by wearing protective gloves when handling inserts. Store used (removed) inserts in a plastic bag or other sealable container until they can be properly disposed in accordance with applicable local, State, and Federal regulations..
Indication
For synchronization of the return to estrus in lactating dairy cows inseminated at the immediately preceding estrus.
Dosage

Administer one intravaginal insert per animal 14 +/- 1 days after insemination. Remove intravaginal insert 7 days later.

Limitations
Do not use in animals with abnormal, immature, or infected genital tracts; or in dairy cows that are fewer than 40 days postpartum for synchronization of estrus or synchronization of the return to estrus; or in anestrous lactating dairy cows less than 42 days or greater than 78 days postpartum for induction of estrous cycles. Do not use an insert more than once. To prevent the potential transmission of venereal and blood borne diseases, the inserts should be disposed after a single use. Administration of vaginal inserts for periods greater than 7 days may result in reduced fertility Product labeling shall bear the following warnings: "Avoid contact with skin by wearing protective gloves when handling inserts. Store used (removed) inserts in a plastic bag or other sealable container until they can be properly disposed in accordance with applicable local, State, and Federal regulations..

Suckled Beef Cows, Replacement Beef and Dairy Heifers

Indication
For the advancement of first pubertal estrus in replacement beef heifers.
Dosage
Administer one intravaginal insert per animal for 7 days.  Administer 25 milligrams dinoprost (5 milliliters of 5 milligrams per milliliter solution) as a single intramuscular injection one day prior to insert removal, on Day 6 of the 7 day administration period.
Limitations
Do not use in animals with abnormal, immature, or infected genital tracts; or in beef cows that are fewer than 20 days postpartum; or in beef or dairy heifers of insufficient size or age for breeding. Do not use an insert more than once. To prevent the potential transmission of venereal and blood borne diseases, the inserts should be disposed after a single use. Administration of vaginal inserts for periods greater than 7 days may result in reduced fertility. This product is approved with the concurrent use of dinoprost solution on day 6 of the 7-day administration period when used for indications: For synchronization of estrus in suckled beef cows and replacement beef and dairy heifers, for advancement of first postpartum estrus in suckled beef cows, and for the advancement of first pubertal estrus in replacement beef heifers. Product labeling shall bear the following warnings: "Avoid contact with skin by wearing protective gloves when handling inserts. Store used (removed) inserts in a plastic bag or other sealable container until they can be properly disposed in accordance with applicable local, State, and Federal regulations.
Indication
For synchronization of estrus in suckled beef cows and replacement beef and dairy heifers.
Dosage
Administer one intravaginal insert per animal for 7 days.  Administer 25 milligrams dinoprost (5 milliliters of 5 milligrams per milliliter solution) as a single intramuscular injection one day prior to insert removal, on Day 6 of the 7 day administration period.
Limitations
Do not use in animals with abnormal, immature, or infected genital tracts; or in beef cows that are fewer than 20 days postpartum; or in beef or dairy heifers of insufficient size or age for breeding. Do not use an insert more than once. To prevent the potential transmission of venereal and blood borne diseases, the inserts should be disposed after a single use. Administration of vaginal inserts for periods greater than 7 days may result in reduced fertility. This product is approved with the concurrent use of dinoprost solution on day 6 of the 7-day administration period when used for indications: For synchronization of estrus in suckled beef cows and replacement beef and dairy heifers, for advancement of first postpartum estrus in suckled beef cows, and for the advancement of first pubertal estrus in replacement beef heifers. Product labeling shall bear the following warnings: "Avoid contact with skin by wearing protective gloves when handling inserts. Store used (removed) inserts in a plastic bag or other sealable container until they can be properly disposed in accordance with applicable local, State, and Federal regulations.
Indication
For advancement of first postpartum estrus in suckled beef cows.
Dosage
Administer one intravaginal insert per animal for 7 days.  Administer 25 milligrams dinoprost (5 milliliters of 5 milligrams per milliliter solution) as a single intramuscular injection one day prior to insert removal, on Day 6 of the 7 day administration period.
Limitations
Do not use in animals with abnormal, immature, or infected genital tracts; or in beef cows that are fewer than 20 days postpartum; or in beef or dairy heifers of insufficient size or age for breeding. Do not use an insert more than once. To prevent the potential transmission of venereal and blood borne diseases, the inserts should be disposed after a single use. Administration of vaginal inserts for periods greater than 7 days may result in reduced fertility. This product is approved with the concurrent use of dinoprost solution on day 6 of the 7-day administration period when used for indications: For synchronization of estrus in suckled beef cows and replacement beef and dairy heifers, for advancement of first postpartum estrus in suckled beef cows, and for the advancement of first pubertal estrus in replacement beef heifers. Product labeling shall bear the following warnings: "Avoid contact with skin by wearing protective gloves when handling inserts. Store used (removed) inserts in a plastic bag or other sealable container until they can be properly disposed in accordance with applicable local, State, and Federal regulations.

EAZI-BREED™ CIDR® Sheep Insert

SPL · SPL

Open original
FDA Structured Product Label

EAZI-BREED™ CIDR® Sheep Insert

Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.

Sponsor
Zoetis Inc.
NADA
141-302
Status
OTC
Form
Solid Matrix
Route
Intravaginal
Species
Sheep, Breeding
Composition / specifications
Each insert contains 0.3 gram progesterone in molded silicone over a flexible nylon spine.

Sheep (Ewes)

Indication
For induction of estrus in ewes (sheep) during seasonal anestrus.
Dosage
One insert per ewe for five days.
Limitations
DO NOT USE in ewes with abnormal, immature or infected genital tracts, in ewes that have never lambed, or an insert more than once. To prevent the potential transmission of venereal and blood borne diseases the EAZI-BREED CIDR Sheep Insert should be disposed after a single use.

Progesterone SPL

SPL · Structured Product Label

Open original
FDA Structured Product Label XML for Progesterone. Use the source link for the full official labeling record.

EAZI-BREED CIDR Sheep Insert SPL

SPL · Structured Product Label

Open original
FDA Structured Product Label XML for EAZI-BREED CIDR Sheep Insert. Use the source link for the full official labeling record.

EAZI-BREED CIDR Cattle Insert SPL

SPL · Structured Product Label

Open original
FDA Structured Product Label XML for EAZI-BREED CIDR Cattle Insert. Use the source link for the full official labeling record.

AX Pharmaceutical Corp SPL

SPL · Structured Product Label

Open original
FDA Structured Product Label XML for AX Pharmaceutical Corp. Use the source link for the full official labeling record.

UCM388266.pdf

FOI · FOI

Open original

UCM235348.pdf

FOI · FOI

Open original

ucm117632.pdf

FOI · FOI

Open original

ucm117628.pdf

FOI · FOI

Open original

UCM190797.pdf

FOI · FOI

Open original

N110315_Supp_04-05-1990.pdf

FOI · FOI summary

Open original

N110315_Supp_01-22-1997.pdf

FOI · FOI summary

Open original

ucm064925.pdf

FOI · FOI summary

Open original

ucm064927.pdf

FOI · FOI summary

Open original

N009576_Supp_08_19_1994.pdf

FOI · FOI summary

Open original

UCM440503.pdf

FOI · FOI summary

Open original

ucm049523.pdf

FOI · FOI summary

Open original
Source metadata:
Veterinary reference (advanced)

Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.

At a Glance

Quick facts and links to official labeling and safety signals.

Data freshness
  • Storefront facts: Source Roxee | Refreshed May 5, 2026, 10:05 AM UTC
    The storefront fact projection used for browse cards and quick facts.
  • Animal Drugs @ FDA: Source FDA | Refreshed May 5, 2026, 10:00 AM UTC
    Applications/products are imported from FDA export data.
  • Animal Drugs @ FDA previews: Source FDA | Refreshed Feb 9, 2026, 3:05 AM UTC
    Label highlights/doc links are fetched from FDA preview endpoints.
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed May 5, 2026, 10:00 AM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
Official (FDA)
Identity: Generic ingredient • FDA branded products available
Official FDA brands: AX Pharmaceutical Corp EAZI-BREED CIDR Cattle Insert EAZI-BREED CIDR Sheep Insert Progesterone
Manufacturer mapping: Multiple FDA labelers
Catalog species: Both • FDA-labeled species: Beef cows and beef heifers (female breeding stock), Dairy cows and heifers (female breeding stock), Sheep
Rx/OTC: OTC
Form/route: Insert, Solid Matrix • Intravaginal
Applications: NADA 141-200 • NADA 141-302
NDC: Packages 54771-1533-1 54771-5207-1 62157-485-01 73377-160-01 73377-160-02 73377-160-03 • Products 54771 62157 73377
Documents: 11 (FOI: 5) • SPL: 2 • Label highlights • Official documents
Safety (openFDA)
Top reactions: Dog 0 • Cat 0 • View
Case summaries: 0
openFDA reports are unverified and do not prove causation.
Diagnosis Codes

Diagnosis-code mappings are not available for this medication yet.

Counseling and Monitoring Highlights

Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.

Owner-facing counseling points
  • For use in suckling beef calves (at least 45 days of age) up to 400 pounds of body weight. For subcutaneous ear implantation, one dose per animal. Do not use in bull calves intended for reproduction. Safety and effectiveness have not been established in veal calves. A withdrawal period has not been established for this product in preruminating calves. Do not use in calves to be processed for veal. This product is approved for concurrent use of dinoprost solution on day 7 of the 7-day administration period when used for the following indications: For synchronization of estrus in lactating dairy cows. Do not use in animals with abnormal, immature, or infected genital tracts; or in dairy cows that are fewer than 40 days postpartum for synchronization of estrus or synchronization of the return to estrus; or in anestrous lactating dairy cows less than 42 days or greater than 78 days postpartum for induction of estrous cycles. Do not use an insert more than once. To prevent the potential transmission of venereal and blood borne diseases, the inserts should be disposed after a single use. Administration of vaginal inserts for periods greater than 7 days may result in reduced fertility. Product labeling shall bear the following warnings: "Avoid contact with skin by wearing protective gloves when handling inserts. Store used (removed) inserts in a plastic bag or other sealable container until they can be properly disposed in accordance with applicable local, State, and Federal regulations. Do not use in animals with abnormal, immature, or infected genital tracts; or in dairy cows that are fewer than 40 days postpartum for synchronization of estrus or synchronization of the return to estrus; or in anestrous lactating dairy cows less than 42 days or greater than 78 days postpartum for induction of estrous cycles. Do not use an insert more than once. To prevent the potential transmission of venereal and blood borne diseases, the inserts should be disposed after a single use. Administration of vaginal inserts for periods greater than 7 days may result in reduced fertility Product labeling shall bear the following warnings: "Avoid contact with skin by wearing protective gloves when handling inserts. Store used (removed) inserts in a plastic bag or other sealable container until they can be properly disposed in accordance with applicable local, State, and Federal regulations.. (Contraindication, High)
Top reaction signals
Behavioral disorder (unspecified) (1)

Identifiers & Packages

Normalized identifiers (NDC/NADA/ANADA) and package metadata from regulator listings.

Identifiers
NADA: 110315 NADA: 141200 NADA: 141302 NADA: 9576 NDC Package: 54771-1533-1 NDC Package: 54771-3902-1 NDC Package: 54771-3903-1 NDC Package: 54771-3903-2 NDC Package: 54771-5207-1 NDC Package: 58198-0507-2 NDC Package: 58198-0792-1 NDC Package: 62157-485-01 NDC Package: 73309-381-01 NDC Package: 73377-133-01 NDC Package: 73377-160-01 NDC Package: 73377-160-02 NDC Package: 73377-160-03 NDC Package: 77382-0200-1 NDC Product: 54771 NDC Product: 58198 NDC Product: 62157 NDC Product: 73309 NDC Product: 73377 NDC Product: 77382
Package NDC Product NDC Form / Route Status
54771-1533-1 54771 -
54771-3902-1 54771 -
54771-3903-1 54771 -
54771-3903-2 54771 -
54771-5207-1 54771 -
58198-0507-2 58198 -
58198-0792-1 58198 -
62157-485-01 62157 -
73309-381-01 73309 -
73377-133-01 73377 -
73377-160-01 73377 -
73377-160-02 73377 -
73377-160-03 73377 -
77382-0200-1 77382 -

Enriched Documents

Documents are tiered by source trust: Official, Clinical, Manufacturer, Marketing.

  • Progesterone SPL • Structured Product Label • Official
    FDA Structured Product Label from the electronic animal drug product listing directory.
  • EAZI-BREED CIDR Sheep Insert SPL • Structured Product Label • Official
    FDA Structured Product Label from the electronic animal drug product listing directory.
  • EAZI-BREED CIDR Cattle Insert SPL • Structured Product Label • Official
    FDA Structured Product Label from the electronic animal drug product listing directory.
  • AX Pharmaceutical Corp SPL • Structured Product Label • Official
    FDA Structured Product Label from the electronic animal drug product listing directory.
  • N110315_Supp_04-05-1990.pdf • FOI summary • Official • July 3, 2024
    FDA FOI summary for application 110315
  • N110315_Supp_01-22-1997.pdf • FOI summary • Official • July 3, 2024
    FDA FOI summary for application 110315
  • ucm064925.pdf • FOI summary • Official • July 3, 2024
    FDA FOI summary for application 110315
  • ucm064927.pdf • FOI summary • Official • July 3, 2024
    FDA FOI summary for application 110315
  • N009576_Supp_08_19_1994.pdf • FOI summary • Official • June 15, 2023
    FDA FOI summary for application 9576
  • UCM440503.pdf • FOI summary • Official • June 15, 2023
    FDA FOI summary for application 9576
  • ucm049523.pdf • FOI summary • Official • June 15, 2023
    FDA FOI summary for application 9576
  • ucm117628.pdf • FOI summary • Official • March 2, 2021
    FDA FOI summary for application 141200
  • ucm117632.pdf • FOI summary • Official • March 2, 2021
    FDA FOI summary for application 141200
  • UCM235348.pdf • FOI summary • Official • March 2, 2021
    FDA FOI summary for application 141200
  • UCM388266.pdf • FOI summary • Official • March 2, 2021
    FDA FOI summary for application 141200
  • UCM190797.pdf • FOI summary • Official • June 1, 2016
    FDA FOI summary for application 141302

Data Sources & Change Log

Every non-trivial field is expected to include provenance and update timestamps.

Official 55 Clinical 9 Manufacturer 0 Marketing 0
Current Field Facts
  • side_effects: Top reported reactions (openFDA): Behavioural disorder NOS. (Clinical, 2026-05-05)
  • side_effects: Top reported reactions (openFDA): Behavioural disorder NOS. (Clinical, 2026-05-03)
  • side_effects: Top reported reactions (openFDA): Behavioural disorder NOS. (Clinical, 2026-04-30)
  • side_effects: Top reported reactions (openFDA): Behavioural disorder NOS. (Clinical, 2026-04-29)
  • side_effects: Top reported reactions (openFDA): Behavioural disorder NOS. (Clinical, 2026-04-28)
  • side_effects: Top reported reactions (openFDA): Behavioural disorder NOS. (Clinical, 2026-04-27)
  • side_effects: Top reported reactions (openFDA): Behavioural disorder NOS. (Clinical, 2026-04-26)
  • side_effects: Top reported reactions (openFDA): Behavioural disorder NOS. (Clinical, 2026-04-25)
  • side_effects: Top reported reactions (openFDA): Behavioural disorder NOS. (Clinical, 2026-04-11)
  • contraindications: For use in suckling beef calves (at least 45 days of age) up to 400 pounds of body weight. For subcutaneous ear implantation, one dose per animal. Do not use i… (Official, 2026-05-05)
  • contraindications: For use in suckling beef calves (at least 45 days of age) up to 400 pounds of body weight. For subcutaneous ear implantation, one dose per animal. Do not use i… (Official, 2026-05-03)
  • contraindications: For use in suckling beef calves (at least 45 days of age) up to 400 pounds of body weight. For subcutaneous ear implantation, one dose per animal. Do not use i… (Official, 2026-04-30)
  • contraindications: For use in suckling beef calves (at least 45 days of age) up to 400 pounds of body weight. For subcutaneous ear implantation, one dose per animal. Do not use i… (Official, 2026-04-29)
  • contraindications: For use in suckling beef calves (at least 45 days of age) up to 400 pounds of body weight. For subcutaneous ear implantation, one dose per animal. Do not use i… (Official, 2026-04-28)
  • contraindications: For use in suckling beef calves (at least 45 days of age) up to 400 pounds of body weight. For subcutaneous ear implantation, one dose per animal. Do not use i… (Official, 2026-04-27)
  • contraindications: For use in suckling beef calves (at least 45 days of age) up to 400 pounds of body weight. For subcutaneous ear implantation, one dose per animal. Do not use i… (Official, 2026-04-26)
  • contraindications: For use in suckling beef calves (at least 45 days of age) up to 400 pounds of body weight. For subcutaneous ear implantation, one dose per animal. Do not use i… (Official, 2026-04-25)
  • contraindications: For use in suckling beef calves (at least 45 days of age) up to 400 pounds of body weight. For subcutaneous ear implantation, one dose per animal. Do not use i… (Official, 2026-04-11)
  • contraindications: For use in suckling beef calves (at least 45 days of age) up to 400 pounds of body weight. For subcutaneous ear implantation, one dose per animal. Do not use i… (Official, 2026-02-12)
  • indications: This supplement provides for the addition of a new indication for induction of estrous cycles in anestrous lactating dairy cows. (Official, 2026-05-05)
Recent Revisions
  • side_effects updated 2026-05-05 10:05 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-05-05 10:05 by etl_backfill • Backfilled from existing medication fields
  • usage updated 2026-05-05 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-05-03 10:05 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-05-03 10:05 by etl_backfill • Backfilled from existing medication fields
  • usage updated 2026-05-03 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-04-30 10:09 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-04-30 10:09 by etl_backfill • Backfilled from existing medication fields
  • usage updated 2026-04-30 10:09 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-04-29 10:05 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-04-29 10:05 by etl_backfill • Backfilled from existing medication fields
  • usage updated 2026-04-29 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-04-28 10:05 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-04-28 10:05 by etl_backfill • Backfilled from existing medication fields
  • usage updated 2026-04-28 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-04-27 10:05 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-04-27 10:05 by etl_backfill • Backfilled from existing medication fields
  • usage updated 2026-04-27 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-04-26 10:06 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-04-26 10:06 by etl_backfill • Backfilled from existing medication fields

FDA Products & Applications (Animal Drugs @ FDA)

Official sponsor/proprietary-name/application-status records linked by active ingredient.

Product Sponsor Application Status Published
EAZI-BREED™ CIDR® Cattle Insert
OTC
Progesterone
Insert • Intravaginal
Label highlights
Official documents
Zoetis Inc. NADA 141-200 Approved Mar 2, 2021
EAZI-BREED™ CIDR® Sheep Insert
OTC
Progesterone
Solid Matrix • Intravaginal
Label highlights
Official documents
Zoetis Inc. NADA 141-302 Approved Jun 1, 2016

Data source: FDA Animal Drugs @ FDA (public search export).

What It's For (FDA Label Highlights)

Extracted from FDA Animal Drugs @ FDA product labeling. Always confirm details with your veterinarian.

Species: Beef cows and beef heifers (female breeding stock) • Dairy cows and heifers (female breeding stock)
Composition / specifications
Each insert contains 1.38 grams of progesterone in molded silicone over a nylon spine.
Lactating Dairy Cows
Indication
For synchronization of estrus in lactating dairy cows.
Dosage
Administer one intravaginal insert per animal for 7 days. Administer 25 milligrams dinoprost (5 milliliters of 5 milligrams per milliliter solution) as a single intramuscular injection insert removal, on Day 7 of the 7 day administration period.
Limitations
This product is approved for concurrent use of dinoprost solution on day 7 of the 7-day administration period when used for the following indications:  For synchronization of estrus in lactating dairy cows. Do not use in animals with abnormal, immature, or infected genital tracts; or in dairy cows that are fewer than 40 days postpartum for synchronization of estrus or synchronization of the return to estrus; or in anestrous lactating dairy cows less than 42 days or greater than 78 days postpartum for induction of estrous cycles. Do not use an insert more than once. To prevent the potential transmission of venereal and blood borne diseases, the inserts should be disposed after a single use. Administration of vaginal inserts for periods greater than 7 days may result in reduced fertility. Product labeling shall bear the following warnings: "Avoid contact with skin by wearing protective gloves when handling inserts. Store used (removed) inserts in a plastic bag or other sealable container until they can be properly disposed in accordance with applicable local, State, and Federal regulations.
Indication
For induction of estrous cycles in anestrous lactating dairy cows.
Dosage
Administer one intravaginal insert per anestrous cow and remove 7 days later.
Limitations
Do not use in animals with abnormal, immature, or infected genital tracts; or in dairy cows that are fewer than 40 days postpartum for synchronization of estrus or synchronization of the return to estrus; or in anestrous lactating dairy cows less than 42 days or greater than 78 days postpartum for induction of estrous cycles. Do not use an insert more than once. To prevent the potential transmission of venereal and blood borne diseases, the inserts should be disposed after a single use. Administration of vaginal inserts for periods greater than 7 days may result in reduced fertility Product labeling shall bear the following warnings: "Avoid contact with skin by wearing protective gloves when handling inserts. Store used (removed) inserts in a plastic bag or other sealable container until they can be properly disposed in accordance with applicable local, State, and Federal regulations..
Indication
For synchronization of the return to estrus in lactating dairy cows inseminated at the immediately preceding estrus.
Dosage

Administer one intravaginal insert per animal 14 +/- 1 days after insemination. Remove intravaginal insert 7 days later.

Limitations
Do not use in animals with abnormal, immature, or infected genital tracts; or in dairy cows that are fewer than 40 days postpartum for synchronization of estrus or synchronization of the return to estrus; or in anestrous lactating dairy cows less than 42 days or greater than 78 days postpartum for induction of estrous cycles. Do not use an insert more than once. To prevent the potential transmission of venereal and blood borne diseases, the inserts should be disposed after a single use. Administration of vaginal inserts for periods greater than 7 days may result in reduced fertility Product labeling shall bear the following warnings: "Avoid contact with skin by wearing protective gloves when handling inserts. Store used (removed) inserts in a plastic bag or other sealable container until they can be properly disposed in accordance with applicable local, State, and Federal regulations..
Suckled Beef Cows, Replacement Beef and Dairy Heifers
Indication
For the advancement of first pubertal estrus in replacement beef heifers.
Dosage
Administer one intravaginal insert per animal for 7 days.  Administer 25 milligrams dinoprost (5 milliliters of 5 milligrams per milliliter solution) as a single intramuscular injection one day prior to insert removal, on Day 6 of the 7 day administration period.
Limitations
Do not use in animals with abnormal, immature, or infected genital tracts; or in beef cows that are fewer than 20 days postpartum; or in beef or dairy heifers of insufficient size or age for breeding. Do not use an insert more than once. To prevent the potential transmission of venereal and blood borne diseases, the inserts should be disposed after a single use. Administration of vaginal inserts for periods greater than 7 days may result in reduced fertility. This product is approved with the concurrent use of dinoprost solution on day 6 of the 7-day administration period when used for indications: For synchronization of estrus in suckled beef cows and replacement beef and dairy heifers, for advancement of first postpartum estrus in suckled beef cows, and for the advancement of first pubertal estrus in replacement beef heifers. Product labeling shall bear the following warnings: "Avoid contact with skin by wearing protective gloves when handling inserts. Store used (removed) inserts in a plastic bag or other sealable container until they can be properly disposed in accordance with applicable local, State, and Federal regulations.
Indication
For synchronization of estrus in suckled beef cows and replacement beef and dairy heifers.
Dosage
Administer one intravaginal insert per animal for 7 days.  Administer 25 milligrams dinoprost (5 milliliters of 5 milligrams per milliliter solution) as a single intramuscular injection one day prior to insert removal, on Day 6 of the 7 day administration period.
Limitations
Do not use in animals with abnormal, immature, or infected genital tracts; or in beef cows that are fewer than 20 days postpartum; or in beef or dairy heifers of insufficient size or age for breeding. Do not use an insert more than once. To prevent the potential transmission of venereal and blood borne diseases, the inserts should be disposed after a single use. Administration of vaginal inserts for periods greater than 7 days may result in reduced fertility. This product is approved with the concurrent use of dinoprost solution on day 6 of the 7-day administration period when used for indications: For synchronization of estrus in suckled beef cows and replacement beef and dairy heifers, for advancement of first postpartum estrus in suckled beef cows, and for the advancement of first pubertal estrus in replacement beef heifers. Product labeling shall bear the following warnings: "Avoid contact with skin by wearing protective gloves when handling inserts. Store used (removed) inserts in a plastic bag or other sealable container until they can be properly disposed in accordance with applicable local, State, and Federal regulations.
Indication
For advancement of first postpartum estrus in suckled beef cows.
Dosage
Administer one intravaginal insert per animal for 7 days.  Administer 25 milligrams dinoprost (5 milliliters of 5 milligrams per milliliter solution) as a single intramuscular injection one day prior to insert removal, on Day 6 of the 7 day administration period.
Limitations
Do not use in animals with abnormal, immature, or infected genital tracts; or in beef cows that are fewer than 20 days postpartum; or in beef or dairy heifers of insufficient size or age for breeding. Do not use an insert more than once. To prevent the potential transmission of venereal and blood borne diseases, the inserts should be disposed after a single use. Administration of vaginal inserts for periods greater than 7 days may result in reduced fertility. This product is approved with the concurrent use of dinoprost solution on day 6 of the 7-day administration period when used for indications: For synchronization of estrus in suckled beef cows and replacement beef and dairy heifers, for advancement of first postpartum estrus in suckled beef cows, and for the advancement of first pubertal estrus in replacement beef heifers. Product labeling shall bear the following warnings: "Avoid contact with skin by wearing protective gloves when handling inserts. Store used (removed) inserts in a plastic bag or other sealable container until they can be properly disposed in accordance with applicable local, State, and Federal regulations.

FDA page: Open in Animal Drugs @ FDA

Species: Sheep, Breeding
Composition / specifications
Each insert contains 0.3 gram progesterone in molded silicone over a flexible nylon spine.
Sheep (Ewes)
Indication
For induction of estrus in ewes (sheep) during seasonal anestrus.
Dosage
One insert per ewe for five days.
Limitations
DO NOT USE in ewes with abnormal, immature or infected genital tracts, in ewes that have never lambed, or an insert more than once. To prevent the potential transmission of venereal and blood borne diseases the EAZI-BREED CIDR Sheep Insert should be disposed after a single use.

FDA page: Open in Animal Drugs @ FDA

Usage

For increased rate of weight gain in growing beef steers fed in confinement for slaughter in a reimplantation program where SYNOVEX® C or SYNOVEX® S is the first implant and a SYNOVEX® S implant is administered approximately 70 days later. Other than ad described on labeling, this implant is not approved for repeated implantation (reimplantation) with any other cattle ear implant in growing beef steers fed in confinement for slaughter as safety and effectiveness have not been evaluated. Do not use in beef calves less than 2 months of age, dairy calves, and veal calves because effectiveness and safety have not been evaluated. Do not use in animals intended for subsequent breeding, or in dairy cows. For increased rate of weight gain in growing beef steers fed in confinement for slaughter in a reimplantation program where SYNOVEX® C or SYNOVEX® S is the first implant and a SYNOVEX® S implant is administered approximately 70 days later. Other than as described on labeling, this implant is not approved for repeated implantation (reimplantation) with any other cattle ear implant in growing beef steers fed in confinement for slaughter as safety and effectiveness have not been evaluated. Do not use in beef calves less than 2 months of age, dairy calves, and veal calves because effectiveness and safety have not been evaluated. Do not use in animals intended for subsequent breeding, or in dairy cows. For increased rate of weight gain in beef calves 45 days of age and older and weighing up to 400 lbs. This implant is not approved for repeated implantation (reimplantation) with this or any other cattle ear implant as safety and effectiveness has not been evaluated.

Source: FDA Animal Drugs @ FDA • Reference

Contraindications

For use in suckling beef calves (at least 45 days of age) up to 400 pounds of body weight. For subcutaneous ear implantation, one dose per animal. Do not use in bull calves intended for reproduction. Safety and effectiveness have not been established in veal calves. A withdrawal period has not been established for this product in preruminating calves. Do not use in calves to be processed for veal. This product is approved for concurrent use of dinoprost solution on day 7 of the 7-day administration period when used for the following indications: For synchronization of estrus in lactating dairy cows. Do not use in animals with abnormal, immature, or infected genital tracts; or in dairy cows that are fewer than 40 days postpartum for synchronization of estrus or synchronization of the return to estrus; or in anestrous lactating dairy cows less than 42 days or greater than 78 days postpartum for induction of estrous cycles. Do not use an insert more than once. To prevent the potential transmission of venereal and blood borne diseases, the inserts should be disposed after a single use. Administration of vaginal inserts for periods greater than 7 days may result in reduced fertility. Product labeling shall bear the following warnings: "Avoid contact with skin by wearing protective gloves when handling inserts. Store used (removed) inserts in a plastic bag or other sealable container until they can be properly disposed in accordance with applicable local, State, and Federal regulations. Do not use in animals with abnormal, immature, or infected genital tracts; or in dairy cows that are fewer than 40 days postpartum for synchronization of estrus or synchronization of the return to estrus; or in anestrous lactating dairy cows less than 42 days or greater than 78 days postpartum for induction of estrous cycles. Do not use an insert more than once. To prevent the potential transmission of venereal and blood borne diseases, the inserts should be disposed after a single use. Administration of vaginal inserts for periods greater than 7 days may result in reduced fertility Product labeling shall bear the following warnings: "Avoid contact with skin by wearing protective gloves when handling inserts. Store used (removed) inserts in a plastic bag or other sealable container until they can be properly disposed in accordance with applicable local, State, and Federal regulations..

Top Reported Reactions (openFDA)

De-duplicated reaction terms grouped by body system from FDA openFDA reports (not verified; does not prove causation).

Behavior
Behavioral disorder (1) • Dog

Showing top 5 for Behavior.

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Adverse Event Case Summaries (openFDA)

These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.

No case-level openFDA reports are linked for this medication yet.

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Overdose Information

No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.

Storage & Handling

No approved storage guidance is linked yet for this ingredient. Use manufacturer packaging and veterinary guidance for handling/storage.

Share Your Thoughts

Let others know your experience or advice regarding this medication.

This medication has not been reviewed by a veterinarian yet.