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Roxee Medication Guide

Protamine Zinc Recombinant Human Insulin

Medication reference facts with explicit FDA-approval, off-label, source-limited, and safety context. Roxee does not sell, prescribe, or dispense medications.

Both Source review pending Biologic/vaccine record Owner quick guide first
Start Symptom Intake Talk to a Vet / Find a Vet Near You

Veterinary professional?

Showing simplified owner view. Switch to Vet View for full technical detail.

Data freshness

Reference facts
Source review pending
No refresh timestamp yet

Roxee is still reviewing source support for this medication profile.

FDA applications
Regulatory match pending
No refresh timestamp yet

Roxee has safety or ingredient evidence for this medication, but a regulatory product/application match is still pending.

Safety reports
Safety data refreshed
Aug 6, 2026, 7:49 p.m.

openFDA reaction terms and case summaries are supporting evidence, not proof of causality.

Source timing details
Source timing details
  • Reference facts: Source Roxee | Refreshed Jul 22, 2026, 7:08 PM UTC
    The reference fact projection used for browse cards and quick facts.
  • openFDA reaction terms: Source FDA openFDA | Refreshed Aug 6, 2026, 7:52 PM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Aug 6, 2026, 7:52 PM UTC
Illustration placeholder
Protamine Zinc Recombinant Human Insulin

Protamine Zinc Recombinant Human Insulin

Drug type: Biologic/vaccine record • Generic profile • Biologic/vaccine record

Both 58% reference complete

Species: Both

Approval status: Vaccine or biologic source record. This record is tracked as vaccine, biologic, strain, recombinant, or lot-level source data. It is not labeled here as an FDA-approved animal drug; use the source documents and veterinarian guidance.

Medication Snapshot

Merged from the current Roxee medication system with field-level provenance, freshness, and completeness tracking.

Protamine Zinc Recombinant Human Insulin

Generic name
Protamine Zinc Recombinant Human Insulin
Species
Both
Completeness
58%
Validation
Incomplete

Side Effects

Top reported reactions (openFDA): Lack of efficacy - NOS, INEFFECTIVE, GLYCEMIC CONTROL, Hypoglycaemia, Vomiting, Death, Lethargy (see also Central nervous system depression in 'Neurological').

FAQ

Both

Source Transparency

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Pet Owner Quick Guide

Start here first for the safest next-step summary before the deeper medication detail.

Roxee still has limited plain-language guidance for this medication. Use the official documents and your veterinarian's instructions for product-specific details.

Used for:

Your vet decides this. Here's what owners typically ask/watch for.

Dosing note:

Exact dosing depends on your pet's species, weight, and health status. Use your veterinarian's instructions for the exact dose and schedule.

What to watch for:

  • wobbly/unsteady walking (1 reports)
  • Inappetence (1 reports)
  • Hypophosphataemia (1 reports)

When to call the vet:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
  • Facial swelling or hives.
  • Blood in vomit or stool.

What to tell or ask your vet today:

  • Is this medicine the right fit for my pet’s current symptoms?
  • Which warning signs mean I should call back right away?
  • How should I handle missed doses or refusal to take the medicine?

Next actions

Talk to a Vet / Find a Vet Near You Save to pet meds Share page Review report evidence
Research brief

Medication Research Insights

A source-aware map of what to know, what is uncertain, and what to verify with your veterinarian.

Source Backed Signals

What to know

Evidence-backed context Limited

Roxee has limited cited overview evidence for Protamine Zinc Recombinant Human Insulin; use the official documents and your veterinarian's instructions for product-specific decisions.

Source: openFDA case USA-USFDACVM-2026-US-008769
Safety signal coverage Reported signals

32 tracked reaction signals; 32 reported cases; 30 serious reports; 2 species groups. These are reporting and label-derived signals for interpretation with a veterinarian.

Source: openFDA case USA-USFDACVM-2026-US-008769
Interpretation guardrail Not causation

Adverse-event reports help form a watch list, but they do not prove the medication caused the reaction and they are not a risk ranking between medications.

Evidence tension

Stronger signal Label / review

Official labels, package inserts, and reviewed summaries carry more weight than isolated reports.

Source: openFDA case USA-USFDACVM-2026-US-008769
Weaker signal Reported data

Case reports and openFDA terms are useful for pattern awareness, but they are incomplete, can include multiple exposures, and do not estimate an individual pet's probability of harm.

Reaction signal map

Most reported reactions Top terms

Unsteady walking (ataxia) (1 reports), Inappetence (1 reports), Hypophosphataemia (1 reports), Hyponatremia (1 reports), Hypokalaemia (1 reports)

Body systems represented Signal grouping

Digestive (1), Neurologic (1), Other (30)

Explore supporting adverse reports

Species and breed lens

Species represented in reports Species lens

Cat (29 reports), Dog (3 reports)

Breed metadata in reports Metadata only

Domestic Shorthair (4), Dog (unknown) (1), Cat (unknown) (1), Russian (1). These are report metadata, not proof that a breed is at higher risk.

What your vet may verify

Fit for this patient Vet check

Verify whether Protamine Zinc Recombinant Human Insulin fits the pet's species, current diagnosis, age, weight, organ status, pregnancy/lactation status, and concurrent medications.

Evidence limitations Evidence review

Separate label-backed warnings from adverse-event reports and owner observations before changing the plan.

What to watch next

Watch list Owner-safe

wobbly/unsteady walking, Inappetence, Hypophosphataemia

Call sooner if Escalation

Repeated vomiting or diarrhea. Severe lethargy (hard to wake, very low energy). Collapse or fainting.

Bottom line: Use this Protamine Zinc Recombinant Human Insulin brief as a structured watch list and source map, not as a reason to start, stop, or change treatment without your veterinarian.
Vet source depth
  1. openFDA case USA-USFDACVM-2026-US-008769 · adverse_reaction · adverse reactions

Evidence

Review status / Updated / Sources

Review status: Clinical reviewer not listed

Updated: April 22, 2026, 10:07 AM UTC

Sources:
Safety & side effects

Side effects to monitor:

  • wobbly/unsteady walking
  • Inappetence
  • Hypophosphataemia

Most reported reactions:

  • Unsteady walking (ataxia) (1 reports)
  • Inappetence (1 reports)
  • Hypophosphataemia (1 reports)
Explore reported case details

Emergency warning signs:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
Talk to a Vet / Find a Vet Near You Start Symptom Intake

Vet Fast Scan

Source-backed clinical checkpoints for quick review.

FDA-labeled species
Not linked yet
Indication / use
Your vet decides this. Here's what owners typically ask/watch for.
Form / route / dose
Confirm product label and patient-specific plan.
Warnings
No structured warnings linked yet.
Adverse-event caveat
openFDA adverse-event cases are reported signals. They are not verified, do not prove causation, and do not estimate a pet's individual risk.
Source docs
No source documents linked yet.

Quick Facts

Official label facts first, then secondary summaries. Marketing content is separated below.

Species: Both
Manufacturer: Manufacturer not confirmed
Identifiers:
NDC Package: 0010-4499-01 NDC Package: 0010-4499-02 NDC Product: 0010

Adverse Reactions

Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.

Reported case explorer

Filter stored openFDA reports by pet and report attributes. Counts describe reports in this data set, not risk.

Clear filters
openFDA adverse-event cases are reported signals. They are not verified, do not prove causation, and do not estimate a pet's individual risk.
Stored reports
21
Matching reports
3
Active filters
2
Selected filters
Reaction: Death by euthanasia Clear Body system: Other Clear
Reset
Drill into common report signals
Lack of efficacy - NOS (11) INEFFECTIVE, GLYCEMIC CONTROL (4) Anaemia NOS (3) Death by euthanasia (3) Other (14) Effectiveness (11) Neurologic (3) Skin & allergy (1)
Showing up to 50 matching reports.

USA-USFDACVM-2026-US-008769

Received 2026-02-28 · MSK · MSK

Serious
Species
Cat
Breed
Russian
Size / weight
Under 10 lb (4.3 Kilogram)
Age
8+ years (19 Year)
Sex
Male Neutered
Region
USA
Reactions
Not drinkingNot eatingDullnessAnaemia NOSCardiac disorder NOSHeart murmurPale mucous membraneAtaxiaOliguriaRenal failureDeath by euthanasiaInappetenceLethargy (see also Central nervous system depression in Neurological)AscitesThird eyelid protrusionLateral recumbencyAcute renal failureDehydrationProlonged capillary refill timeHyperglycaemiaSplenic neoplasm NOSHead bobbingElevated blood urea nitrogen (BUN)Elevated creatinineAbnormal radiograph findingAzotaemiaDecreased packed cell volume (PCV)DullHypernatraemia
Body systems
OtherNeurologic
Outcomes
Euthanized

USA-USFDACVM-2026-US-007782

Received 2026-01-28 · MSK · MSK

Serious
Species
Dog
Breed
Rottweiler
Size / weight
100+ lb (47.62 Kilogram)
Age
4-7 years (4 Year)
Sex
Male Neutered
Region
USA
Reactions
Urinary bladder disorder NOSAnaemia NOSSepticaemiaUnresponsive to stimuliDeath by euthanasiaEmphysema NOS (see Respiratory for pulmonary emphysema)
Body systems
Other
Outcomes
Euthanized

USA-USFDACVM-2026-US-003069

Received 2026-01-22 · MSK · MSK

Serious
Species
Dog
Breed
Rottweiler
Size / weight
100+ lb (47.62 Kilogram)
Age
4-7 years (4 Year)
Sex
Male Neutered
Region
USA
Reactions
Urinary bladder disorder NOSAnaemia NOSSepticaemiaUnresponsive to stimuliDeath by euthanasiaEmphysema NOS (see Respiratory for pulmonary emphysema)
Body systems
Other
Outcomes
Euthanized

Tap or hover a reaction to see what it means in plain language.

Tracked signals
32
Reported cases
32
Serious reports
30
Species represented
2
Grouped by Body System
Digestive (1) · Vomiting Neurologic (1) · Unsteady walking (ataxia) Other (30) · INEFFECTIVE, GLYCEMIC CONTROL, Inappetence, Hypophosphataemia
Most Reported Reactions
Reaction Body system Cases Species Serious cases
Neurologic 1 Cat 1
Other 1 Cat 1
Other 1 Cat 1
Other 1 Cat 1
Other 1 Cat 1
Other 1 Cat 1
Other 1 Cat 1
Other 1 Cat 1

Species coverage: Cat (29) Dog (3)

View detailed reaction table
Reaction Body system Species Seriousness Frequency Reports
Digestive Cat Non-serious - 1
Neurologic Cat Serious - 1
Other Cat Non-serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Source metadata:
Veterinary reference (advanced)

Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.

At a Glance

Quick facts and links to official labeling and safety signals.

Data freshness
  • Reference facts: Source Roxee | Refreshed Jul 22, 2026, 7:08 PM UTC
    The reference fact projection used for browse cards and quick facts.
  • openFDA reaction terms: Source FDA openFDA | Refreshed Aug 6, 2026, 7:52 PM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Aug 6, 2026, 7:52 PM UTC
Official (FDA)
Identity: Generic ingredient • No FDA branded products linked
No official FDA brand rows linked yet for this ingredient.
Case-reported brands (openFDA): MSK
Catalog species: Both
Safety (openFDA)
Top reactions: Dog 13 • Cat 42 • View
Case summaries: 21 (showing 8) • View
openFDA reports are unverified and do not prove causation.
Diagnosis Codes

Diagnosis-code mappings are not available for this medication yet.

Counseling and Monitoring Highlights

Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.

Top reaction signals
Unsteady walking (ataxia) (1) Inappetence (1) Hypophosphataemia (1) Hyponatremia (1) Hypokalaemia (1) Hypoglycaemia (1) Hypochloraemia (1) Hypernatraemia (1)

Identifiers & Packages

Normalized identifiers (NDC/NADA/ANADA) and package metadata from regulator listings.

Identifiers
NDC Package: 0010-4499-01 NDC Package: 0010-4499-02 NDC Product: 0010
Package NDC Product NDC Form / Route Status
0010-4499-01 0010 -
0010-4499-02 0010 -

Data Sources & Change Log

Every non-trivial field is expected to include provenance and update timestamps.

Official 88 Clinical 1 Manufacturer 0 Marketing 0
Current Field Facts
  • side_effects: Top reported reactions (openFDA): Lack of efficacy - NOS, INEFFECTIVE, GLYCEMIC CONTROL, Hypoglycaemia, Vomiting, Death, Lethargy (see also Central nervous sys… (Clinical, 2026-04-11)
  • side_effects: Top reported reactions (openFDA): Lack of efficacy - NOS, INEFFECTIVE, GLYCEMIC CONTROL, Hypoglycaemia, Vomiting, Death, Lethargy (see also Central nervous sys… (Official, 2026-07-22)
  • side_effects: Top reported reactions (openFDA): Lack of efficacy - NOS, INEFFECTIVE, GLYCEMIC CONTROL, Hypoglycaemia, Vomiting, Death, Lethargy (see also Central nervous sys… (Official, 2026-07-22)
  • side_effects: Top reported reactions (openFDA): Lack of efficacy - NOS, INEFFECTIVE, GLYCEMIC CONTROL, Hypoglycaemia, Vomiting, Death, Lethargy (see also Central nervous sys… (Official, 2026-07-22)
  • side_effects: Top reported reactions (openFDA): Lack of efficacy - NOS, INEFFECTIVE, GLYCEMIC CONTROL, Hypoglycaemia, Vomiting, Death, Lethargy (see also Central nervous sys… (Official, 2026-07-20)
  • side_effects: Top reported reactions (openFDA): Lack of efficacy - NOS, INEFFECTIVE, GLYCEMIC CONTROL, Hypoglycaemia, Vomiting, Death, Lethargy (see also Central nervous sys… (Official, 2026-07-19)
  • side_effects: Top reported reactions (openFDA): Lack of efficacy - NOS, INEFFECTIVE, GLYCEMIC CONTROL, Hypoglycaemia, Vomiting, Death, Lethargy (see also Central nervous sys… (Official, 2026-07-16)
  • side_effects: Top reported reactions (openFDA): Lack of efficacy - NOS, INEFFECTIVE, GLYCEMIC CONTROL, Hypoglycaemia, Vomiting, Death, Lethargy (see also Central nervous sys… (Official, 2026-07-16)
  • side_effects: Top reported reactions (openFDA): Lack of efficacy - NOS, INEFFECTIVE, GLYCEMIC CONTROL, Hypoglycaemia, Vomiting, Death, Lethargy (see also Central nervous sys… (Official, 2026-07-13)
  • side_effects: Top reported reactions (openFDA): Lack of efficacy - NOS, INEFFECTIVE, GLYCEMIC CONTROL, Hypoglycaemia, Vomiting, Death, Lethargy (see also Central nervous sys… (Official, 2026-07-12)
  • side_effects: Top reported reactions (openFDA): Lack of efficacy - NOS, INEFFECTIVE, GLYCEMIC CONTROL, Hypoglycaemia, Vomiting, Death, Lethargy (see also Central nervous sys… (Official, 2026-07-11)
  • side_effects: Top reported reactions (openFDA): Lack of efficacy - NOS, INEFFECTIVE, GLYCEMIC CONTROL, Hypoglycaemia, Vomiting, Death, Lethargy (see also Central nervous sys… (Official, 2026-07-11)
  • side_effects: Top reported reactions (openFDA): Lack of efficacy - NOS, INEFFECTIVE, GLYCEMIC CONTROL, Hypoglycaemia, Vomiting, Death, Lethargy (see also Central nervous sys… (Official, 2026-07-11)
  • side_effects: Top reported reactions (openFDA): Lack of efficacy - NOS, INEFFECTIVE, GLYCEMIC CONTROL, Hypoglycaemia, Vomiting, Death, Lethargy (see also Central nervous sys… (Official, 2026-07-10)
  • side_effects: Top reported reactions (openFDA): Lack of efficacy - NOS, INEFFECTIVE, GLYCEMIC CONTROL, Hypoglycaemia, Vomiting, Death, Lethargy (see also Central nervous sys… (Official, 2026-07-07)
  • side_effects: Top reported reactions (openFDA): Lack of efficacy - NOS, INEFFECTIVE, GLYCEMIC CONTROL, Hypoglycaemia, Vomiting, Death, Lethargy (see also Central nervous sys… (Official, 2026-07-06)
  • side_effects: Top reported reactions (openFDA): Lack of efficacy - NOS, INEFFECTIVE, GLYCEMIC CONTROL, Hypoglycaemia, Vomiting, Death, Lethargy (see also Central nervous sys… (Official, 2026-07-06)
  • side_effects: Top reported reactions (openFDA): Lack of efficacy - NOS, INEFFECTIVE, GLYCEMIC CONTROL, Hypoglycaemia, Vomiting, Death, Lethargy (see also Central nervous sys… (Official, 2026-07-03)
  • side_effects: Top reported reactions (openFDA): Lack of efficacy - NOS, INEFFECTIVE, GLYCEMIC CONTROL, Hypoglycaemia, Vomiting, Death, Lethargy (see also Central nervous sys… (Official, 2026-07-03)
  • side_effects: Top reported reactions (openFDA): Lack of efficacy - NOS, INEFFECTIVE, GLYCEMIC CONTROL, Hypoglycaemia, Vomiting, Death, Lethargy (see also Central nervous sys… (Official, 2026-07-02)
Recent Revisions
  • side_effects updated 2026-07-22 19:08 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-07-22 18:40 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-07-22 08:29 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-07-20 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-07-19 13:48 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-07-16 16:34 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-07-16 15:43 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-07-13 10:06 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-07-12 17:56 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-07-11 19:04 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-07-11 08:49 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-07-11 08:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-07-10 21:24 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-07-07 10:06 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-07-06 20:16 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-07-06 08:13 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-07-03 20:16 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-07-03 11:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-07-02 22:45 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-07-01 23:29 by etl_backfill • Backfilled from existing medication fields

Top Reported Reactions (openFDA)

De-duplicated reaction terms grouped by body system from FDA openFDA reports (not verified; does not prove causation).

Digestive
Vomiting (1) • Cat

Showing top 5 for Digestive.

Neurologic
Unsteady walking (1) • Cat

Showing top 5 for Neurologic.

Other
INEFFECTIVE, GLYCEMIC CONTROL (1) • Cat Inappetence (1) • Cat Hypophosphataemia (1) • Cat Hyponatremia (1) • Cat Hypokalaemia (1) • Cat
Show more (25)
Hypoglycaemia (1) • Cat Hypochloraemia (1) • Cat Hypernatraemia (1) • Cat Hyperglycaemia (1) • Cat Heart murmur (1) • Cat Head bobbing (1) • Cat Haemangiosarcoma (1) • Cat Granuloma (1) • Dog Emphysema NOS (1) • Dog Elevated total bilirubin (1) • Cat Elevated creatinine (1) • Cat Elevated blood urea nitrogen (1) • Cat Elevated alanine aminotransferase (1) • Cat Dullness (1) • Cat Dull (1) • Cat Dehydration (1) • Cat Decreased packed cell volume (1) • Cat Death by euthanasia (1) • Cat Death (1) • Cat Cardiac disorder NOS (1) • Cat Azotaemia (1) • Cat Ascites (1) • Cat Anaemia NOS (1) • Dog Acute renal failure (1) • Cat Abnormal radiograph finding (1) • Cat

Showing top 5 for Other.

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Adverse Event Case Summaries (openFDA)

These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.

Cat, Domestic Shorthair, Male, 6.196 kilogram • Drug: MSK, Suspension, Unknown, Frequency: 12 per hour • Reactions: Lack of efficacy - NOS • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2026-US-014674
  • Serious AE: No
  • Treated For AE: No
  • Sex: Male
  • Weight: 6.196 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Suspension
  • Frequency: 12 per hour
Reactions Reported:
Lack of efficacy - NOS
Outcomes: Outcome Unknown

Cat, Domestic Shorthair, Male, 11 year, 3.27 kilogram • Drug: MSK, Suspension, Subcutaneous, Frequency: 12 per hour • Reactions: Weight loss, Lack of efficacy - NOS • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2026-US-013712
  • Serious AE: No
  • Treated For AE: No
  • Sex: Male
  • Age: 11.00 Year
  • Weight: 3.270 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Subcutaneous
  • Form: Suspension
  • Frequency: 12 per hour
Reactions Reported:
Weight loss Lack of efficacy - NOS
Outcomes: Outcome Unknown

Dog, Dog (unknown), Female, 24.607 kilogram • Drug: MSK, Suspension, Subcutaneous, Frequency: 12 per hour • Reactions: INEFFECTIVE, GLYCEMIC CONTROL • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2026-US-013688
  • Serious AE: No
  • Treated For AE: No
  • Sex: Female
  • Weight: 24.607 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Subcutaneous
  • Form: Suspension
  • Frequency: 12 per hour
Reactions Reported:
INEFFECTIVE, GLYCEMIC CONTROL
Outcomes: Outcome Unknown

Cat, Cat (unknown), Male, 11 year, 4.536 kilogram • Drug: MSK, Suspension, Unknown, Dose: 0.33 [iU] per kilogram, Frequency: 12 per hour • Reactions: Lack of efficacy - NOS • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2026-US-013368
  • Serious AE: No
  • Treated For AE: No
  • Sex: Male
  • Age: 11.00 Year
  • Weight: 4.536 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Suspension
  • Dose: 0.33 [iU] per kilogram
  • Frequency: 12 per hour
Reactions Reported:
Lack of efficacy - NOS
Outcomes: Outcome Unknown

Cat, Domestic Shorthair, Male, 4 year, 9.435 kilogram • Drug: MSK, Suspension, Subcutaneous, Dose: 3 [iU] per animal, Frequency: 12 per hour • Reactions: INEFFECTIVE, GLYCEMIC CONTROL, INEFFECTIVE, LOSS OF EFFECT • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2026-US-013100
  • Serious AE: No
  • Treated For AE: No
  • Sex: Male
  • Age: 4.00 Year
  • Weight: 9.435 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Subcutaneous
  • Form: Suspension
  • Dose: 3 [iU] per animal
  • Frequency: 12 per hour
Reactions Reported:
INEFFECTIVE, GLYCEMIC CONTROL INEFFECTIVE, LOSS OF EFFECT
Outcomes: Outcome Unknown

Cat, Domestic Shorthair, Female, 15 year, 6.123 kilogram • Drug: MSK, Suspension, Subcutaneous, Frequency: 12 per hour • Reactions: Stumbling gait, Ocular discharge, Oral measuring or administration device use error • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2026-US-013099
  • Serious AE: No
  • Treated For AE: No
  • Sex: Female
  • Age: 15.00 Year
  • Weight: 6.123 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Subcutaneous
  • Form: Suspension
  • Frequency: 12 per hour
Reactions Reported:
Stumbling gait Ocular discharge Oral measuring or administration device use error
Outcomes: Outcome Unknown

Cat, Russian, Male, 19 year, 4.3 kilogram • Drug: MSK, Subcutaneous • Reactions: Not drinking, Not eating, Dullness, Anaemia NOS, Cardiac disorder NOS… • Outcome: Euthanized

  • Report ID: USA-USFDACVM-2026-US-008769
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 19.00 Year
  • Weight: 4.300 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Subcutaneous
Reactions Reported:
Not drinking Not eating Dullness Anaemia NOS Cardiac disorder NOS Heart murmur Pale mucous membrane Unsteady walking (ataxia) Oliguria Renal failure Death by euthanasia Inappetence Tiredness (lethargy) Ascites Third eyelid protrusion Lateral recumbency Acute renal failure Dehydration Prolonged capillary refill time Hyperglycaemia Splenic neoplasm NOS Head bobbing Elevated blood urea nitrogen Elevated creatinine Abnormal radiograph finding Azotaemia Decreased packed cell volume Dull Hypernatraemia
Outcomes: Euthanized

Dog, Crossbred Canine/dog, Male, 10 year, 6.804 kilogram • Drug: MSK, Suspension, Subcutaneous, Frequency: 1 per day • Reactions: Lack of efficacy - NOS • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2026-US-010721
  • Serious AE: No
  • Treated For AE: No
  • Sex: Male
  • Age: 10.00 Year
  • Weight: 6.804 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Subcutaneous
  • Form: Suspension
  • Frequency: 1 per day
Reactions Reported:
Lack of efficacy - NOS
Outcomes: Outcome Unknown

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Overdose Information

No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.

Storage & Handling

No approved storage guidance is linked yet for this ingredient. Use manufacturer packaging and veterinary guidance for handling/storage.

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This medication has not been reviewed by a veterinarian yet.