Roxee Meds Catalog

Pyrantel Pamoate/Praziquantel

Medication catalog facts with explicit FDA-approval, off-label, source-limited, and safety context.

Both Catalog complete FDA data linked Non-Rx Tablet Multiple FDA labelers Official label facts Owner quick guide first

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FDA applications

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Sponsor, product, and application records imported from Animal Drugs @ FDA.

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openFDA reaction terms and case summaries are supporting evidence, not proof of causality.

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Storefront facts: Source Roxee | Refreshed Apr 22, 2026, 10:07 AM UTC
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Animal Drugs @ FDA: Source FDA | Refreshed May 5, 2026, 10:00 AM UTC
Applications/products are imported from FDA export data.
Animal Drugs @ FDA previews: Source FDA | Refreshed Feb 9, 2026, 3:05 AM UTC
Label highlights/doc links are fetched from FDA preview endpoints.
Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed May 5, 2026, 10:00 AM UTC
Package/product NDCs from FDA’s electronic listing directory (XLS).

Evidence

Reviewed / Updated / Sources

Reviewed by: Not available

Last reviewed: April 22, 2026

Updated: April 22, 2026, 10:06 AM UTC

Sources:

FDA application profile · official_label
FDA application profile · official_label
Medication usage source · fda_animal_drugs
openFDA case USA-USFDACVM-2017-US-036073 · adverse_reaction
FOI · document

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Pyrantel Pamoate/Praziquantel

Drug type: Generic ingredient • Branded profile • FDA branded products available

Both Tablet Non-Rx 100% storefront ready

Species: Both

Manufacturer: Multiple FDA labelers

Medication Snapshot

Merged from the current Roxee medication system with field-level provenance, freshness, and completeness tracking.

Pyrantel Pamoate/Praziquantel

For the treatment and control of roundworms ( Toxocara canis and Toxascaris leonine ), hookworms ( Ancylostoma caninum , Ancylostoma braziliense , and Uncinaria stenocephala ), and tapeworms ( Dipylidium caninum and Taenia pisiformis ) in dogs and puppies. For removal of the common parasites of cats and kittens including tapeworms ( Dipylidium caninum, Taenia taeniaeformis ), hookworms ( Ancylostoma tubaeforme ), and large roundworms ( Toxocara cati ). Species commonly shown: Both, Cat And Kitten, Excluding Under 2 Months Of Age Or Under 2 Pounds Weight, Dogs And Puppies.

Generic name

Pyrantel Pamoate/Praziquantel

Brand names

Drontal™ Tablets, Virbantel® Worm X Plus®, Drontal, WORMXPLUS

Manufacturer

Multiple FDA labelers

Species

Both, Cat And Kitten, Excluding Under 2 Months Of Age Or Under 2 Pounds Weight, Dogs And Puppies

Dosage forms

Tablet, Tablet (Chewable)

Prescription

Non-prescription

Completeness

100%

Validation

Complete

Brand names

Drontal™ Tablets Virbantel® Worm X Plus® Drontal WORMXPLUS Triple Wormer 7 Way De-Wormer Virbantel

Dosage forms

Tablet Tablet (Chewable)

Indications / Uses

Warnings / Contraindications

Consult your veterinarian for assistance in the diagnosis, treatment, and control of parasitism.Do not de-worm a dog or puppy that is sick. Consult a veterinarian for diagnosis of the illness. VIRBANTEL® Flavored Chewables are safe for use in puppies 12 weeks or older and adult dogs. Safety in breeding dogs and pregnant bitches has not been tested. Consult your veterinarian for assistance in the diagnosis, treatment, and control of parasitism. Do not de-worm a dog or puppy that is sick. Consult a veterinarian for diagnosis of the illness. Worm X Plus® Flavored Chewables are safe for use in puppies 12 weeks or older and adult dogs. Safety in breeding dogs and pregnant bitches has not been tested. May be given directly by mouth or in a small amount of food. Do not withhold food prior to or after treatment. If reinfection occurs, treatment may be repeated. Consult your veterinarian before giving to sick or pregnant animals. Consult your veterinarian for assistance in the diagnosis, treatment, and control of parasitism. Not for use in kittens less than 2 months of age or weighing less than 2.0 pounds.

Consult your veterinarian for assistance in the diagnosis, treatment, and control of parasitism.Do not de-worm a dog or puppy that is sick. Consult a veterinarian for diagnosis of the illness. VIRBANTEL® Flavored Chewables are safe for use in puppies 12 weeks or older and adult dogs. Safety in breeding dogs and pregnant bitches has not been tested. Consult your veterinarian for assistance in the diagnosis, treatment, and control of parasitism. Do not de-worm a dog or puppy that is sick. Consult a veterinarian for diagnosis of the illness. Worm X Plus® Flavored Chewables are safe for use in puppies 12 weeks or older and adult dogs. Safety in breeding dogs and pregnant bitches has not been tested. May be given directly by mouth or in a small amount of food. Do not withhold food prior to or after treatment. If reinfection occurs, treatment may be repeated. Consult your veterinarian before giving to sick or pregnant animals. Consult your veterinarian for assistance in the diagnosis, treatment, and control of parasitism. Not for use in kittens less than 2 months of age or weighing less than 2.0 pounds.

Side Effects

Top reported reactions (openFDA): Vomiting, Lethargy (see also Central nervous system depression in 'Neurological'), Diarrhoea, Overdose, Drug administration error, Emesis (multiple).

FAQ

Both, Cat And Kitten, Excluding Under 2 Months Of Age Or Under 2 Pounds Weight, Dogs And Puppies

No. Roxee does not currently show this as prescription-only.

Tablet, Tablet (Chewable)

Source Transparency

Verified source: https://www.roxee.ai/meds/
Verified source: https://animaldrugsatfda.fda.gov
Verified source: https://animaldrugsatfda.fda.gov/adafda/views/#/search
Verified source: https://api.fda.gov/animalandveterinary/event.json
Verified source: https://animaldrugsatfda.fda.gov/adafda/app/search/public/document/downloadFoi/558
Verified source: https://animaldrugsatfda.fda.gov/adafda/app/search/public/document/downloadFoi/815
Last refreshed: Apr 22, 2026, 10:07 a.m.
Last verified: Apr 22, 2026, 10:06 a.m.
Validation status: Complete

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Pet Owner Quick Guide

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Used for:

Dosing note:

Exact dosing depends on your pet's species, weight, and health status. Use your veterinarian's instructions for the exact dose and schedule.

What to watch for:

Consult your veterinarian for assistance in the diagnosis, treatment, and control of parasitism.Do not de-worm a dog or puppy that is sick
Consult a veterinarian for diagnosis of the illness
VIRBANTEL® Flavored Chewables are safe for use in puppies 12 weeks or older and adult dogs
Safety in breeding dogs and pregnant bitches has not been tested
Consult your veterinarian for assistance in the diagnosis, treatment, and control of parasitism
Do not de-worm a dog or puppy that is sick
Worm X Plus® Flavored Chewables are safe for use in puppies 12 weeks or older and adult dogs
May be given directly by mouth or in a small amount of food
Do not withhold food prior to or after treatment
If reinfection occurs, treatment may be repeated
Consult your veterinarian before giving to sick or pregnant animals
Not for use in kittens less than 2 months of age or weighing less than 2.0 pounds
Vomiting (1 reports)
Underdose (1 reports)
very low energy (1 reports)

When to call the vet:

Repeated vomiting or diarrhea.
Severe lethargy (hard to wake, very low energy).
Collapse or fainting.
Trouble breathing.
Facial swelling or hives.
Blood in vomit or stool.

What to tell or ask your vet today:

Is this medicine the right fit for my pet’s current symptoms?
Which warning signs mean I should call back right away?
How should I handle missed doses or refusal to take the medicine?

Major cautions & emergency warning signs

Side effects to monitor:

Consult your veterinarian for assistance in the diagnosis, treatment, and control of parasitism.Do not de-worm a dog or puppy that is sick
Consult a veterinarian for diagnosis of the illness
VIRBANTEL® Flavored Chewables are safe for use in puppies 12 weeks or older and adult dogs
Safety in breeding dogs and pregnant bitches has not been tested
Consult your veterinarian for assistance in the diagnosis, treatment, and control of parasitism

Most reported reactions:

Vomiting (1 reports)
Underdose (1 reports)
Tiredness (lethargy) (1 reports)

Emergency warning signs:

Repeated vomiting or diarrhea.
Severe lethargy (hard to wake, very low energy).
Collapse or fainting.
Trouble breathing.

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Quick Facts

Official label facts first, then secondary summaries. Marketing content is separated below.

Species: Both

Manufacturer: Multiple FDA labelers

Form: Tablet, Tablet (Chewable)

Identifiers:

NADA: 141008 NADA: 141261 NDC Package: 21091-641-01 NDC Package: 21091-641-02 NDC Package: 21091-641-03 NDC Package: 21091-642-01 NDC Package: 21091-642-02 NDC Package: 21091-642-03 NDC Package: 21091-703-02 NDC Package: 21091-703-12 NDC Package: 30798-185-61 NDC Package: 30798-185-71 NDC Package: 30798-186-61 NDC Package: 30798-186-71 NDC Package: 51311-504-02 NDC Package: 51311-505-04 NDC Package: 51311-506-06 NDC Package: 51311-507-08 NDC Package: 51311-738-10 NDC Package: 51311-741-10

Source metadata:

https://animaldrugsatfda.fda.gov/adafda/views/#/home/previewsearch/141261 · official_label · FDA application profile
https://animaldrugsatfda.fda.gov/adafda/views/#/home/previewsearch/141008 · official_label · FDA application profile
https://animaldrugsatfda.fda.gov · fda_animal_drugs · Medication usage source

Warnings / Contraindications

High: Consult your veterinarian for assistance in the diagnosis, treatment, and control of parasitism.Do not de-worm a dog or puppy that is sick. Consult a veterinarian for diagnosis of the illness. VIRBANTEL® Flavored Chewables are safe for use in puppies 12 weeks or older and adult dogs. Safety in breeding dogs and pregnant bitches has not been tested. Consult your veterinarian for assistance in the diagnosis, treatment, and control of parasitism. Do not de-worm a dog or puppy that is sick. Consult a veterinarian for diagnosis of the illness. Worm X Plus® Flavored Chewables are safe for use in puppies 12 weeks or older and adult dogs. Safety in breeding dogs and pregnant bitches has not been tested. May be given directly by mouth or in a small amount of food. Do not withhold food prior to or after treatment. If reinfection occurs, treatment may be repeated. Consult your veterinarian before giving to sick or pregnant animals. Consult your veterinarian for assistance in the diagnosis, treatment, and control of parasitism. Not for use in kittens less than 2 months of age or weighing less than 2.0 pounds.

Source metadata:

https://animaldrugsatfda.fda.gov · fda_animal_drugs · Contraindication source

Adverse Reactions

Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.

Tap or hover a reaction to see what it means in plain language.

Tracked signals

Reported cases

Serious reports

Species represented

Grouped by Body System

Digestive (2) · Vomiting, Diarrhea Neurologic (2) · Tiredness (lethargy), Lethargy (see also Central nervous system depression in 'Neurological') Effectiveness (4) · Lack of efficacy (endoparasite) - Toxocara/Toxascaris, Lack of efficacy (endoparasite) - tapeworm, Lack of efficacy (endoparasite) - roundworm NOS Other (10) · Underdose, Drug dose administration interval too short, Cough

Most Reported Reactions

Body system	Cases	Species
Digestive	1	Cat, Dog
Other	1	Dog
Neurologic	1	Cat
Effectiveness	1	Dog
Effectiveness	1	Dog
Effectiveness	1	Dog
Effectiveness	1	Dog
Other	1	Dog

Species coverage: Dog (14) Cat (4)

View detailed reaction table

Body system	Species	Seriousness	Frequency	Reports
Digestive	Cat	Non-serious	-	1
Other	Dog	Non-serious	-	1
Neurologic	Cat	Non-serious	-	1
Effectiveness	Dog	Non-serious	-	1
Effectiveness	Dog	Non-serious	-	1
Effectiveness	Dog	Non-serious	-	1
Effectiveness	Dog	Non-serious	-	1
Other	Dog	Non-serious	-	1
Digestive	Dog	Non-serious	-	1
Other	Dog	Non-serious	-	1
Other	Dog	Non-serious	-	1
Other	Cat	Non-serious	-	1
Other	Dog	Unknown	-	-
Other	Dog	Unknown	-	-
Other	Dog	Unknown	-	-
Neurologic	Cat	Unknown	-	-
Other	Dog	Unknown	-	-
Other	Dog	Unknown	-	-

Source metadata:

https://api.fda.gov/animalandveterinary/event.json · adverse_reaction · openFDA case USA-USFDACVM-2017-US-036073

Documents

Owner handouts and official technical documents open on-page first, with the original source still one click away.

Owner handouts

No owner handouts linked yet.

Official label / PI

No official label or package insert links yet.

SPL

FOI

Virbantel®

SPL · SPL

Open original

FDA Structured Product Label

Virbantel® Worm X Plus®

Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.

Sponsor: Virbac AH, Inc.
NADA: 141-261
Status: OTC
Form: Tablet (Chewable)
Route: Oral
Species: Dogs And Puppies

Composition / specifications

Each chewable tablet contains: 30 mg praziquantel and 30 mg pyrantel pamoate (For Small Dogs and Puppies) or 114 mg praziquantel and 114 mg pyrantel pamoate (For Medium and Large Dogs).

Dogs (Puppies and Small Dogs 6.0-25 Lbs)

Indication

For the treatment and control of roundworms (Toxocara canis and Toxascaris leonine), hookworms (Ancylostoma caninum, Ancylostoma braziliense, and Uncinaria stenocephala), and tapeworms (Dipylidium caninum and Taenia pisiformis) in dogs and puppies.

Dosage

Administer a minimum dose of 5 milligrams praziquantel and 5 milligrams pyrantel pamoate per kilogram body weight (2.27 milligrams praziquantel and 2.27 milligrams pyrantel pamoate per pound body weight) according to the dosing tables on labeling.

Limitations

Dogs (Medium and Large Dogs- Greater than 25 Lbs)

Indication

Dosage

Limitations

Worm X Plus®

SPL · SPL

Open original

FDA Structured Product Label

Virbantel® Worm X Plus®

Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.

Sponsor: Virbac AH, Inc.
NADA: 141-261
Status: OTC
Form: Tablet (Chewable)
Route: Oral
Species: Dogs And Puppies

Composition / specifications

Each chewable tablet contains: 30 mg praziquantel and 30 mg pyrantel pamoate (For Small Dogs and Puppies) or 114 mg praziquantel and 114 mg pyrantel pamoate (For Medium and Large Dogs).

Dogs (Puppies and Small Dogs 6.0-25 Lbs)

Indication

Dosage

Limitations

Dogs (Medium and Large Dogs- Greater than 25 Lbs)

Indication

Dosage

Limitations

Drontal™ Tablets

SPL · SPL

Open original

FDA Structured Product Label

Drontal™ Tablets

Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.

Sponsor: Elanco US Inc.
NADA: 141-008
Status: OTC
Form: Tablet
Route: Oral
Species: Cat And Kitten, Excluding Under 2 Months Of Age Or Under 2 Pounds Weight

Composition / specifications

Each tablet contains 18.2 mg praziquantel and 72.6 mg pyrantel base as pyrantel pamoate.

Cats and Kittens (Greater Than 2 Months of Age Or At Least 2 Lbs)

Indication

For removal of the common parasites of cats and kittens including tapeworms (Dipylidium caninum, Taenia taeniaeformis), hookworms (Ancylostoma tubaeforme), and large roundworms (Toxocara cati).

Dosage

Administer a minimum dose of 2.27 mg praziquantel and 9.2 pyrantel pamoate per pound of bodyweight according to the dosing tables on labeling.

Limitations

May be given directly by mouth or in a small amount of food. Do not withhold food prior to or after treatment. If reinfection occurs, treatment may be repeated. Consult your veterinarian before giving to sick or pregnant animals. Consult your veterinarian for assistance in the diagnosis, treatment, and control of parasitism. Not for use in kittens less than 2 months of age or weighing less than 2.0 pounds.