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Roxee Medication Guide

Sometribove

Medication reference facts with explicit FDA-approval, off-label, source-limited, and safety context. Roxee does not sell, prescribe, or dispense medications.

Both Reference partial Livestock/food-animal use Union Agener Inc Official label facts Owner quick guide first
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Showing simplified owner view. Switch to Vet View for full technical detail.

Data freshness

Reference facts
Reference refreshed
Jun 22, 2026, 10:41 a.m.

Roxee has a partial reference profile for this medication. Some primary facts still need verification.

FDA applications
FDA application data refreshed
Jun 22, 2026, 10:41 a.m.

Sponsor, product, and application records imported from Animal Drugs @ FDA.

Safety reports
No safety reports linked
No refresh timestamp yet

openFDA reaction terms and case summaries are supporting evidence, not proof of causality.

Source timing details
Source timing details
  • Reference facts: Source Roxee | Refreshed Jun 22, 2026, 10:41 AM UTC
    The reference fact projection used for browse cards and quick facts.
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed Jun 22, 2026, 10:41 AM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
Image coming soon
Sometribove

Sometribove

Drug type: Food-animal record • Branded profile • Livestock/food-animal use

Both 81% reference complete

Species: Both

Approval status: Food-animal or livestock record. This source record is for livestock or food-animal use, not a dog/cat medication profile. Food-animal rules, withdrawal intervals, and residue restrictions may apply.

Medication Snapshot

Merged from the current Roxee medication system with field-level provenance, freshness, and completeness tracking.

Sometribove

To increase production of marketable milk in healthy lactating dairy cows. Species commonly shown: Both.

Generic name
Sometribove
Brand names
Posilac
Manufacturer
Union Agener Inc
Species
Both
Completeness
81%
Validation
Incomplete
Brand names
Posilac

Indications / Uses

To increase production of marketable milk in healthy lactating dairy cows.

Warnings / Contraindications

Use in lactating dairy cows only. Safety to replacement bulls born to treated dairy cows has not been established. Inject subcutaneously. Avoid injections within 2 weeks of expected slaughter to minimize injection site blemishes on carcass.There is no milk discard or preslaughter withdrawal period.Use may reduce pregnancy rates and increase days open. Treated cows are at an increased risk for mastitis and higher milk somatic cell counts. Use care to differentiate increased body temperature due to use of this product from an increased body temperature that may occur due to illness. Cows treated with this product may have more enlarged hocks and disorders of the foot region. Use may reduce hemoglobin and hematocrit values during treatment.Human warning: Avoid prolonged or repeated contact with eyes and skin.

  • Use in lactating dairy cows only. Safety to replacement bulls born to treated dairy cows has not been established. Inject subcutaneously. Avoid injections within 2 weeks of expected slaughter to minimize injection site blemishes on carcass.There is no milk discard or preslaughter withdrawal period.Use may reduce pregnancy rates and increase days open. Treated cows are at an increased risk for mastitis and higher milk somatic cell counts. Use care to differentiate increased body temperature due to use of this product from an increased body temperature that may occur due to illness. Cows treated with this product may have more enlarged hocks and disorders of the foot region. Use may reduce hemoglobin and hematocrit values during treatment.Human warning: Avoid prolonged or repeated contact with eyes and skin.

FAQ

Both

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Pet Owner Quick Guide

Start here first for the safest next-step summary before the deeper medication detail.

Used for:

To increase production of marketable milk in healthy lactating dairy cows.

Dosing note:

Exact dosing depends on your pet's species, weight, and health status. Use your veterinarian's instructions for the exact dose and schedule.

What to watch for:

  • Use in lactating dairy cows only
  • Safety to replacement bulls born to treated dairy cows has not been established
  • Inject subcutaneously
  • Avoid injections within 2 weeks of expected slaughter to minimize injection site blemishes on carcass.There is no milk discard or preslaughter withdrawal period.Use may reduce pregnancy rates and increase days open
  • Treated cows are at an increased risk for mastitis and higher milk somatic cell counts
  • Use care to differentiate increased body temperature due to use of this product from an increased body temperature that may occur due to illness
  • Cows treated with this product may have more enlarged hocks and disorders of the foot region
  • Use may reduce hemoglobin and hematocrit values during treatment.Human warning: Avoid prolonged or repeated contact with eyes and skin

When to call the vet:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
  • Facial swelling or hives.
  • Blood in vomit or stool.

What to tell or ask your vet today:

  • Is this medicine the right fit for my pet’s current symptoms?
  • Which warning signs mean I should call back right away?
  • How should I handle missed doses or refusal to take the medicine?

Next actions

Talk to a Vet / Find a Vet Near You Save to pet meds Share page Review report evidence
Research brief

Medication Research Insights

A source-aware map of what to know, what is uncertain, and what to verify with your veterinarian.

Source Backed Limited Signals

What to know

Evidence-backed context Limited

Roxee has limited cited overview evidence for Sometribove; use the official documents and your veterinarian's instructions for product-specific decisions.

Source: openFDA adverse-event data
Safety signal coverage No signal rollup

No source-backed adverse-reaction rollup is linked yet. That is a data gap, not proof that no reactions occur.

Source: openFDA adverse-event data
Interpretation guardrail Not causation

Adverse-event reports help form a watch list, but they do not prove the medication caused the reaction and they are not a risk ranking between medications.

Evidence tension

Stronger signal Label / review

Official labels, package inserts, and reviewed summaries carry more weight than isolated reports.

Source: openFDA adverse-event data
Weaker signal Reported data

Case reports and openFDA terms are useful for pattern awareness, but they are incomplete, can include multiple exposures, and do not estimate an individual pet's probability of harm.

Reaction signal map

Reaction signal map Limited data

No source-backed adverse-reaction rollup is linked yet for this medication. Use the owner watch list, official documents, and veterinary guidance.

What your vet may verify

Fit for this patient Vet check

Verify whether Sometribove fits the pet's species, current diagnosis, age, weight, organ status, pregnancy/lactation status, and concurrent medications.

Evidence limitations Evidence review

Separate label-backed warnings from adverse-event reports and owner observations before changing the plan.

What to watch next

Watch list Owner-safe

Use in lactating dairy cows only, Safety to replacement bulls born to treated dairy cows has not been established, Inject subcutaneously, Avoid injections within 2 weeks of expected slaughter to minimize injection site blemishes on carcas, Treated cows are at an increased risk for mastitis and higher milk somatic cell counts

Call sooner if Escalation

Repeated vomiting or diarrhea. Severe lethargy (hard to wake, very low energy). Collapse or fainting.

Bottom line: Roxee has limited reaction-signal depth for Sometribove right now. Use veterinary instructions, official documents, and direct clinic guidance for decisions.
Vet source depth
  1. openFDA adverse-event data · openfda · adverse reactions
  2. Medication contraindications · safety_warning · warnings contraindications
  3. Structured Product Label · document · documents
  4. FOI summary · document · documents
  5. FOI summary · document · documents
  6. FOI summary · document · documents

Evidence

Review status / Updated / Sources

Review status: Clinical reviewer not listed

Updated: May 2, 2026, 10:05 AM UTC

Sources:
Safety & side effects

Side effects to monitor:

  • Use in lactating dairy cows only
  • Safety to replacement bulls born to treated dairy cows has not been established
  • Inject subcutaneously
  • Avoid injections within 2 weeks of expected slaughter to minimize injection site blemishes on carcass.There is no milk discard or preslaughter withdrawal period.Use may reduce pregnancy rates and increase days open
  • Treated cows are at an increased risk for mastitis and higher milk somatic cell counts

Emergency warning signs:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
Talk to a Vet / Find a Vet Near You Start Symptom Intake

Vet Fast Scan

Source-backed clinical checkpoints for quick review.

FDA-labeled species
Not linked yet
Indication / use
To increase production of marketable milk in healthy lactating dairy cows.
Form / route / dose
Confirm product label and patient-specific plan.
Warnings
  • High: Use in lactating dairy cows only. Safety to replacement bulls born to treated dairy cows has not been established. Inje…
Adverse-event caveat
No stored openFDA case explorer rows are linked yet.
Source docs

Quick Facts

Official label facts first, then secondary summaries. Marketing content is separated below.

Species: Both
Manufacturer: Union Agener Inc
Identifiers:
NADA: 140872 NDC Package: 86106-0225-1 NDC Package: 86106-0225-2 NDC Package: 86106-0225-3 NDC Product: 86106

Warnings / Contraindications

Use in lactating dairy cows only. Safety to replacement bulls born to treated dairy cows has not been established. Inject subcutaneously. Avoid injections within 2 weeks of expected slaughter to minimize injection site blemishes on carcass.There is no milk discard or preslaughter withdrawal period.Use may reduce pregnancy rates and increase days open. Treated cows are at an increased risk for mastitis and higher milk somatic cell counts. Use care to differentiate increased body temperature due to use of this product from an increased body temperature that may occur due to illness. Cows treated with this product may have more enlarged hocks and disorders of the foot region. Use may reduce hemoglobin and hematocrit values during treatment.Human warning: Avoid prolonged or repeated contact with eyes and skin.

  • High: Use in lactating dairy cows only. Safety to replacement bulls born to treated dairy cows has not been established. Inject subcutaneously. Avoid injections within 2 weeks of expected slaughter to minimize injection site blemishes on carcass.There is no milk discard or preslaughter withdrawal period.Use may reduce pregnancy rates and increase days open. Treated cows are at an increased risk for mastitis and higher milk somatic cell counts. Use care to differentiate increased body temperature due to use of this product from an increased body temperature that may occur due to illness. Cows treated with this product may have more enlarged hocks and disorders of the foot region. Use may reduce hemoglobin and hematocrit values during treatment.Human warning: Avoid prolonged or repeated contact with eyes and skin.
Source metadata:

Source Documents

The most useful source links appear first; full previews and metadata stay in the veterinary/professional layer.

Use original documents to confirm product-specific warnings, ingredients, and handling details with your veterinarian.

Posilac SPL SPL · Structured Product Label ucm050022.pdf FOI · FOI summary ucm050023.pdf FOI · FOI summary

Full source previews and metadata remain in the veterinary/professional layer.

Owner handouts

0
No owner handouts linked yet.

Official label / PI

0
No official label or package insert links yet.

SPL

1

FOI

3

Posilac SPL

SPL · Structured Product Label

Open original
FDA Structured Product Label XML for Posilac. Use the source link for the full official labeling record.

ucm050022.pdf

FOI · FOI summary

Open original

ucm050023.pdf

FOI · FOI summary

Open original

ucm050024.pdf

FOI · FOI summary

Open original
Source metadata:
Veterinary reference (advanced)

Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.

At a Glance

Quick facts and links to official labeling and safety signals.

Data freshness
  • Reference facts: Source Roxee | Refreshed Jun 22, 2026, 10:41 AM UTC
    The reference fact projection used for browse cards and quick facts.
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed Jun 22, 2026, 10:41 AM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
Official (FDA)
Identity: Generic ingredient • FDA branded products available
Official FDA brands: Posilac
Manufacturer mapping: Union Agener Inc
Catalog species: Both
NDC: Packages 86106-0225-1 86106-0225-2 86106-0225-3 • Products 86106
Safety (openFDA)
Top reactions: Dog 0 • Cat 0
Case summaries: 0
openFDA reports are unverified and do not prove causation.
Diagnosis Codes

Diagnosis-code mappings are not available for this medication yet.

Counseling and Monitoring Highlights

Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.

Owner-facing counseling points
  • Use in lactating dairy cows only. Safety to replacement bulls born to treated dairy cows has not been established. Inject subcutaneously. Avoid injections within 2 weeks of expected slaughter to minimize injection site blemishes on carcass.There is no milk discard or preslaughter withdrawal period.Use may reduce pregnancy rates and increase days open. Treated cows are at an increased risk for mastitis and higher milk somatic cell counts. Use care to differentiate increased body temperature due to use of this product from an increased body temperature that may occur due to illness. Cows treated with this product may have more enlarged hocks and disorders of the foot region. Use may reduce hemoglobin and hematocrit values during treatment.Human warning: Avoid prolonged or repeated contact with eyes and skin. (Contraindication, High)

Identifiers & Packages

Normalized identifiers (NDC/NADA/ANADA) and package metadata from regulator listings.

Identifiers
NADA: 140872 NDC Package: 86106-0225-1 NDC Package: 86106-0225-2 NDC Package: 86106-0225-3 NDC Product: 86106
Package NDC Product NDC Form / Route Status
86106-0225-1 86106 -
86106-0225-2 86106 -
86106-0225-3 86106 -

Enriched Documents

Documents are tiered by source trust: Official, Clinical, Manufacturer, Marketing.

  • Posilac SPL • Structured Product Label • Official
    FDA Structured Product Label from the electronic animal drug product listing directory.
  • ucm050022.pdf • FOI summary • Official • May 6, 2020
    FDA FOI summary for application 140872
  • ucm050023.pdf • FOI summary • Official • May 6, 2020
    FDA FOI summary for application 140872
  • ucm050024.pdf • FOI summary • Official • May 6, 2020
    FDA FOI summary for application 140872

Data Sources & Change Log

Every non-trivial field is expected to include provenance and update timestamps.

Official 69 Clinical 6 Manufacturer 0 Marketing 0
Current Field Facts
  • contraindications: Use in lactating dairy cows only. Safety to replacement bulls born to treated dairy cows has not been established. Inject subcutaneously. Avoid injections with… (Clinical, 2026-05-02)
  • contraindications: Use in lactating dairy cows only. Safety to replacement bulls born to treated dairy cows has not been established. Inject subcutaneously. Avoid injections with… (Clinical, 2026-04-15)
  • contraindications: Use in lactating dairy cows only. Safety to replacement bulls born to treated dairy cows has not been established. Inject subcutaneously. Avoid injections with… (Clinical, 2026-04-11)
  • usage: To increase production of marketable milk in healthy lactating dairy cows. (Clinical, 2026-05-02)
  • usage: To increase production of marketable milk in healthy lactating dairy cows. (Clinical, 2026-04-15)
  • usage: To increase production of marketable milk in healthy lactating dairy cows. (Clinical, 2026-04-11)
  • contraindications: Use in lactating dairy cows only. Safety to replacement bulls born to treated dairy cows has not been established. Inject subcutaneously. Avoid injections with… (Official, 2026-04-30)
  • contraindications: Use in lactating dairy cows only. Safety to replacement bulls born to treated dairy cows has not been established. Inject subcutaneously. Avoid injections with… (Official, 2026-02-12)
  • manufacturer_name: Union Agener Inc (Official, 2026-06-22)
  • manufacturer_name: Union Agener Inc (Official, 2026-06-22)
  • manufacturer_name: Union Agener Inc (Official, 2026-06-21)
  • manufacturer_name: Union Agener Inc (Official, 2026-06-20)
  • manufacturer_name: Union Agener Inc (Official, 2026-06-13)
  • manufacturer_name: Union Agener Inc (Official, 2026-06-12)
  • manufacturer_name: Union Agener Inc (Official, 2026-06-12)
  • manufacturer_name: Union Agener Inc (Official, 2026-06-11)
  • manufacturer_name: Union Agener Inc (Official, 2026-06-11)
  • manufacturer_name: Union Agener Inc (Official, 2026-06-10)
  • manufacturer_name: Union Agener Inc (Official, 2026-06-09)
  • manufacturer_name: Union Agener Inc (Official, 2026-06-08)
Recent Revisions
  • contraindications updated 2026-05-02 10:05 by etl_backfill • Backfilled from existing medication fields
  • usage updated 2026-05-02 10:05 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-04-30 10:09 by etl_backfill • Backfilled from existing medication fields
  • usage updated 2026-04-30 10:09 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-04-15 10:04 by etl_backfill • Backfilled from existing medication fields
  • usage updated 2026-04-15 10:04 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-04-11 10:05 by etl_backfill • Backfilled from existing medication fields
  • usage updated 2026-04-11 10:05 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields
  • usage updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields

FDA Products & Applications (Animal Drugs @ FDA)

Official sponsor/proprietary-name/application-status records linked by active ingredient.

Product Sponsor Application Status Published

Data source: FDA Animal Drugs @ FDA (public search export).

Usage

To increase production of marketable milk in healthy lactating dairy cows.

Contraindications

Use in lactating dairy cows only. Safety to replacement bulls born to treated dairy cows has not been established. Inject subcutaneously. Avoid injections within 2 weeks of expected slaughter to minimize injection site blemishes on carcass.There is no milk discard or preslaughter withdrawal period.Use may reduce pregnancy rates and increase days open. Treated cows are at an increased risk for mastitis and higher milk somatic cell counts. Use care to differentiate increased body temperature due to use of this product from an increased body temperature that may occur due to illness. Cows treated with this product may have more enlarged hocks and disorders of the foot region. Use may reduce hemoglobin and hematocrit values during treatment.Human warning: Avoid prolonged or repeated contact with eyes and skin.

Adverse Event Case Summaries (openFDA)

These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.

No case-level openFDA reports are linked for this medication yet.

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Overdose Information

No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.

Storage & Handling

No approved storage guidance is linked yet for this ingredient. Use manufacturer packaging and veterinary guidance for handling/storage.

Share Your Thoughts

Let others know your experience or advice regarding this medication.

This medication has not been reviewed by a veterinarian yet.