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Roxee Meds Catalog

Tramadol

Medication catalog facts with explicit FDA-approval, off-label, source-limited, and safety context.

Both Source review pending Source coverage pending Owner quick guide first
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Data freshness

Storefront facts
Source review pending
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Roxee is still reviewing source support for this medication profile.

FDA applications
Regulatory match pending
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Roxee has safety or ingredient evidence for this medication, but a regulatory product/application match is still pending.

Safety reports
Safety data refreshed
May 5, 2026, 10:01 a.m.

openFDA reaction terms and case summaries are supporting evidence, not proof of causality.

Source timing details
Source timing details
  • Storefront facts: Source Roxee | Refreshed May 5, 2026, 10:05 AM UTC
    The storefront fact projection used for browse cards and quick facts.
  • openFDA reaction terms: Source FDA openFDA | Refreshed May 5, 2026, 10:04 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed May 5, 2026, 10:04 AM UTC

Evidence

Reviewed / Updated / Sources

Reviewed by: Not available

Last reviewed: April 15, 2026

Updated: April 15, 2026, 10:04 AM UTC

Sources:
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Tramadol

Tramadol

Drug type: Generic ingredient • Generic profile • Source coverage pending

Both 80% storefront ready

Species: Both

Approval status: Source coverage pending. Roxee has limited supporting content for this record, but no on-page official FDA animal-drug document is linked yet. Treat it as source-limited until the ETL backfill adds official coverage.

Medication Snapshot

Merged from the current Roxee medication system with field-level provenance, freshness, and completeness tracking.

Tramadol

Senvelgo (velagliflozin oral solution) is approved in cats for control of hyperglycemia associated with diabetes mellitus. Species commonly shown: Both.

Generic name
Tramadol
Species
Both
Completeness
80%
Validation
Incomplete

Indications / Uses

Senvelgo (velagliflozin oral solution) is approved in cats for control of hyperglycemia associated with diabetes mellitus.

Side Effects

Top reported reactions (openFDA): Vomiting, Lethargy (see also Central nervous system depression in 'Neurological'), Diarrhoea, Death by euthanasia, Lack of efficacy - NOS, Elevated alanine aminotransferase (ALT).

FAQ

Both

Source Transparency

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Pet Owner Quick Guide

Start here first for the safest next-step summary before the deeper medication detail.

Roxee still has limited plain-language guidance for this medication. Use the official documents and your veterinarian's instructions for product-specific details.

Used for:

Your vet decides this. Here's what owners typically ask/watch for.

Dosing note:

Exact dosing depends on your pet's species, weight, and health status. Use your veterinarian's instructions for the exact dose and schedule.

What to watch for:

  • Hypochloraemia (1 reports)
  • Hyperglycaemia (1 reports)
  • Hyperactivity (1 reports)

When to call the vet:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
  • Facial swelling or hives.
  • Blood in vomit or stool.

What to tell or ask your vet today:

  • Is this medicine the right fit for my pet’s current symptoms?
  • Which warning signs mean I should call back right away?
  • How should I handle missed doses or refusal to take the medicine?
Major cautions & emergency warning signs

Side effects to monitor:

  • Hypochloraemia
  • Hyperglycaemia
  • Hyperactivity

Most reported reactions:

  • Hypochloraemia (1 reports)
  • Hyperglycaemia (1 reports)
  • Hyperactivity (1 reports)

Emergency warning signs:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
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Quick Facts

Official label facts first, then secondary summaries. Marketing content is separated below.

Species: Both
Manufacturer: Manufacturer not confirmed

Adverse Reactions

Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.

Tap or hover a reaction to see what it means in plain language.

Tracked signals
32
Reported cases
32
Serious reports
23
Species represented
2
Grouped by Body System
Digestive (3) · Loss of appetite, Diarrhea, Decreased appetite Neurologic (1) · Head tilt - neurological disorder Behavior (1) · Behavioral disorder (unspecified) Other (27) · Hypochloraemia, Hyperglycaemia, Hyperactivity
Most Reported Reactions
Reaction Body system Cases Species Serious cases
Other 1 Dog 1
Other 1 Dog 1
Other 1 Dog 1
Other 1 Dog 1
Other 1 Dog 1
Other 1 Dog 1
Neurologic 1 Dog 1
Other 1 Dog 1

Species coverage: Dog (29) Cat (3)

View detailed reaction table
Reaction Body system Species Seriousness Frequency Reports
Digestive Dog Non-serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Neurologic Dog Serious - 1
Other Cat Non-serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Non-serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Non-serious - 1
Other Cat Non-serious - 1
Digestive Dog Serious - 1
Digestive Cat Non-serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Non-serious - 1
Other Dog Serious - 1
Behavior Dog Non-serious - 1
Other Dog Serious - 1
Other Dog Non-serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Source metadata:
Veterinary reference (advanced)

Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.

At a Glance

Quick facts and links to official labeling and safety signals.

Data freshness
  • Storefront facts: Source Roxee | Refreshed May 5, 2026, 10:05 AM UTC
    The storefront fact projection used for browse cards and quick facts.
  • openFDA reaction terms: Source FDA openFDA | Refreshed May 5, 2026, 10:04 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed May 5, 2026, 10:04 AM UTC
Official (FDA)
Identity: Generic ingredient • No FDA branded products linked
No official FDA brand rows linked yet for this ingredient.
Case-reported brands (openFDA): MSK
Catalog species: Both
Safety (openFDA)
Top reactions: Dog 36 • Cat 0 • View
Case summaries: 7 (showing 7) • View
openFDA reports are unverified and do not prove causation.
Diagnosis Codes

Diagnosis-code mappings are not available for this medication yet.

Counseling and Monitoring Highlights

Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.

Top reaction signals
Hypochloraemia (1) Hyperglycaemia (1) Hyperactivity (1) Horizontal nystagmus (1) Hepatomegaly (1) Hemiparesis (1) Head tilt - neurological disorder (1) Gastroenteritis (1)

Data Sources & Change Log

Every non-trivial field is expected to include provenance and update timestamps.

Official 19 Clinical 8 Manufacturer 0 Marketing 0
Current Field Facts
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-21)
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-20)
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-19)
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-17)
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-16)
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-16)
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-15)
  • side_effects: Top reported reactions (openFDA): Vomiting, Lethargy (see also Central nervous system depression in 'Neurological'), Diarrhoea, Death by euthanasia, Lack of ef… (Clinical, 2026-04-11)
  • side_effects: Top reported reactions (openFDA): Vomiting, Lethargy (see also Central nervous system depression in 'Neurological'), Diarrhoea, Death by euthanasia, Lack of ef… (Official, 2026-05-05)
  • side_effects: Top reported reactions (openFDA): Vomiting, Lethargy (see also Central nervous system depression in 'Neurological'), Diarrhoea, Death by euthanasia, Lack of ef… (Official, 2026-05-03)
  • side_effects: Top reported reactions (openFDA): Vomiting, Lethargy (see also Central nervous system depression in 'Neurological'), Diarrhoea, Death by euthanasia, Lack of ef… (Official, 2026-04-30)
  • side_effects: Top reported reactions (openFDA): Vomiting, Lethargy (see also Central nervous system depression in 'Neurological'), Diarrhoea, Death by euthanasia, Lack of ef… (Official, 2026-04-29)
  • side_effects: Top reported reactions (openFDA): Vomiting, Lethargy (see also Central nervous system depression in 'Neurological'), Diarrhoea, Death by euthanasia, Lack of ef… (Official, 2026-04-28)
  • side_effects: Top reported reactions (openFDA): Vomiting, Lethargy (see also Central nervous system depression in 'Neurological'), Diarrhoea, Death by euthanasia, Lack of ef… (Official, 2026-04-27)
  • side_effects: Top reported reactions (openFDA): Vomiting, Lethargy (see also Central nervous system depression in 'Neurological'), Diarrhoea, Death by euthanasia, Lack of ef… (Official, 2026-04-26)
  • side_effects: Top reported reactions (openFDA): Vomiting, Lethargy (see also Central nervous system depression in 'Neurological'), Diarrhoea, Death by euthanasia, Lack of ef… (Official, 2026-04-25)
  • side_effects: Top reported reactions (openFDA): Vomiting, Lethargy (see also Central nervous system depression in 'Neurological'), Diarrhoea, Death by euthanasia, Lack of ef… (Official, 2026-04-17)
  • side_effects: Top reported reactions (openFDA): Vomiting, Lethargy (see also Central nervous system depression in 'Neurological'), Diarrhoea, Death by euthanasia, Lack of ef… (Official, 2026-04-15)
  • side_effects: Top reported reactions (openFDA): Vomiting, Lethargy (see also Central nervous system depression in 'Neurological'), Diarrhoea, Death by euthanasia, Lack of ef… (Official, 2026-04-15)
  • side_effects: Top reported reactions (openFDA): Vomiting, Lethargy (see also Central nervous system depression in 'Neurological'), Diarrhoea, Death by euthanasia, Lack of ef… (Official, 2026-02-12)
Recent Revisions
  • side_effects updated 2026-05-05 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-05-03 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-04-30 10:09 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-04-29 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-04-28 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-04-27 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-04-26 10:06 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-04-25 10:05 by etl_backfill • Backfilled from existing medication fields
  • monitoring updated 2026-04-21 10:06 by curated_loader • Clinical monitoring context for feline diabetes management.
  • usage updated 2026-04-21 10:06 by curated_loader • Usage statement from FDA warning letter and approved-product context.
  • drug_profile_type updated 2026-04-21 10:06 by curated_loader • FDA source confirms Senvelgo as a branded approved product.
  • manufacturer_name updated 2026-04-21 10:06 by curated_loader • FDA warning letter identifies the approved sponsor/manufacturer.
  • brand_names updated 2026-04-21 10:06 by curated_loader • FDA warning letter references Senvelgo as the approved animal drug.
  • approval_reference updated 2026-04-21 10:06 by curated_loader • Official FDA application reference for Senvelgo.
  • monitoring updated 2026-04-20 10:08 by curated_loader • Clinical monitoring context for feline diabetes management.
  • usage updated 2026-04-20 10:08 by curated_loader • Usage statement from FDA warning letter and approved-product context.
  • drug_profile_type updated 2026-04-20 10:08 by curated_loader • FDA source confirms Senvelgo as a branded approved product.
  • manufacturer_name updated 2026-04-20 10:08 by curated_loader • FDA warning letter identifies the approved sponsor/manufacturer.
  • brand_names updated 2026-04-20 10:08 by curated_loader • FDA warning letter references Senvelgo as the approved animal drug.
  • approval_reference updated 2026-04-20 10:08 by curated_loader • Official FDA application reference for Senvelgo.

Top Reported Reactions (openFDA)

De-duplicated reaction terms grouped by body system from FDA openFDA reports (not verified; does not prove causation).

Digestive
Loss of appetite (1) • Dog Diarrhea (1) • Dog Decreased appetite (1) • Cat

Showing top 5 for Digestive.

Neurologic
Head tilt - neurological disorder (1) • Dog

Showing top 5 for Neurologic.

Behavior
Behavioral disorder (1) • Dog

Showing top 5 for Behavior.

Other
Hypochloraemia (1) • Dog Hyperglycaemia (1) • Dog Hyperactivity (1) • Dog Horizontal nystagmus (1) • Dog Hepatomegaly (1) • Dog
Show more (22)
Hemiparesis (1) • Dog Growling (1) • Cat Gastroenteritis (1) • Dog Gall bladder & bile duct disorder NOS (1) • Dog Fluid in abdomen NOS (1) • Dog Elevated symmetrical dimethylarginine (1) • Dog Elevated serum alkaline phosphatase (1) • Dog Elevated gamma-glutamyl transferase (1) • Dog Elevated amylase (1) • Dog Elevated alanine aminotransferase (1) • Dog Disorientation (1) • Dog Dilated pupils (1) • Cat Death by euthanasia (1) • Dog Colitis (1) • Dog Cardiac disorder NOS (1) • Dog Bradycardia (1) • Dog Bone and joint disorder NOS (1) • Dog Arthritis (1) • Dog Arrhythmia (1) • Dog Abnormal ultrasound finding (1) • Dog Abnormal radiograph finding (1) • Dog Abnormal echocardiogram (1) • Dog

Showing top 5 for Other.

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Adverse Event Case Summaries (openFDA)

These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.

Dog, ['Retriever - Labrador', 'Dog (unknown)'], Female, 10.5 year, 45.359 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Arthritis, Lack of efficacy - NOS, Elevated serum alkaline phosphatase, Elevated alanine aminotransferase, Hyperglycaemia… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-074330
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 10.50 Year
  • Weight: 45.359 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Unassigned
Reactions Reported:
Arthritis Lack of efficacy - NOS Elevated serum alkaline phosphatase Elevated alanine aminotransferase Hyperglycaemia Overdose Medication error NOS
Outcomes: Ongoing

Dog, ['Shepherd (unspecified)', 'Dog (unknown)'], Female, 11 year, 22.498 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Seizure NOS • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-073003
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 11.00 Year
  • Weight: 22.498 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Unassigned
Reactions Reported:
Seizure NOS
Outcomes: Ongoing

Dog, ['Shepherd (unspecified)', 'Dog (unknown)'], Female, 11 year, 22.498 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Vestibular disorder NOS, Wobbliness, Horizontal nystagmus, Head tilt - neurological disorder, Nausea… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-072782
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 11.00 Year
  • Weight: 22.498 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Unassigned
Reactions Reported:
Vestibular disorder NOS Wobbliness Horizontal nystagmus Head tilt - neurological disorder Nausea Vomiting Lack of efficacy - NOS Overdose
Outcomes: Ongoing

Dog, Retriever - Labrador, Female, 14 year, 31.8 kilogram • Drug: MSK, Tablet, Oral • Reactions: Watery diarrhoea • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-073465
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 14.00 Year
  • Weight: 31.800 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet
Reactions Reported:
Watery diarrhoea
Outcomes: Outcome Unknown

Dog, Sheepdog (unspecified), Male, 10 year, 51.71 kilogram • Drug: MSK, Solution/drops, Oral • Reactions: Wobbliness, Unable to walk, Spinal pain NOS, Hemiparesis, Impaired proprioception… • Outcome: Euthanized

  • Report ID: USA-USFDACVM-2025-US-073471
  • Serious AE: Yes
  • Treated For AE: No
  • Sex: Male
  • Age: 10.00 Year
  • Weight: 51.710 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Solution/drops
Reactions Reported:
Wobbliness Unable to walk Spinal pain NOS Hemiparesis Impaired proprioception Death by euthanasia Urinary incontinence
Outcomes: Euthanized

Dog, ['Rottweiler', 'Retriever - Labrador'], Male, 14 year, 27.76 kilogram • Drug: MSK, Unknown • Reactions: Proprioception deficit, Musculoskeletal disorder NOS, Tiredness (lethargy), Loss of appetite, Reluctant to move… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-072463
  • Serious AE: No
  • Treated For AE: Yes
  • Sex: Male
  • Age: 14.00 Year
  • Weight: 27.760 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Proprioception deficit Musculoskeletal disorder NOS Tiredness (lethargy) Loss of appetite Reluctant to move Bradycardia Arrhythmia Fever Lymphocytosis Leucocytosis NOS Low thyroxine Elevated symmetrical dimethylarginine Urinary tract infection
Outcomes: Ongoing

Dog, Retriever - Labrador, Female, 9 year, 44.452 kilogram • Drug: MSK, Unknown • Reactions: Vomiting, Not eating, Low platelet count • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-074731
  • Serious AE: No
  • Treated For AE: Yes
  • Sex: Female
  • Age: 9.00 Year
  • Weight: 44.452 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Vomiting Not eating Low platelet count
Outcomes: Outcome Unknown

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Overdose Information

No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.

Storage & Handling

No approved storage guidance is linked yet for this ingredient. Use manufacturer packaging and veterinary guidance for handling/storage.

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