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Roxee Meds Catalog

Trazodone

Medication catalog facts with explicit FDA-approval, off-label, source-limited, and safety context.

Both Catalog partial Not FDA-approved for animals Multiple FDA labelers Official label facts Owner quick guide first
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Data freshness

Storefront facts
Catalog refreshed
May 5, 2026, 10:05 a.m.

Roxee has a partial storefront projection for this medication. Some primary facts still need verification.

FDA applications
FDA application data refreshed
May 5, 2026, 10:00 a.m.

Sponsor, product, and application records imported from Animal Drugs @ FDA.

Safety reports
Safety data refreshed
May 5, 2026, 10:01 a.m.

openFDA reaction terms and case summaries are supporting evidence, not proof of causality.

Source timing details
Source timing details
  • Storefront facts: Source Roxee | Refreshed May 5, 2026, 10:05 AM UTC
    The storefront fact projection used for browse cards and quick facts.
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed May 5, 2026, 10:00 AM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
  • openFDA reaction terms: Source FDA openFDA | Refreshed May 5, 2026, 10:04 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed May 5, 2026, 10:04 AM UTC

Evidence

Reviewed / Updated / Sources

Reviewed by: Not available

Last reviewed: April 15, 2026

Updated: April 15, 2026, 10:04 AM UTC

Sources:
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Trazodone

Trazodone

Drug type: Generic ingredient • Branded profile • Not FDA-approved for animals

Both 81% storefront ready

Species: Both

Approval status: Not FDA-approved as an animal drug. No FDA-approved animal-drug application is linked for this record. It may represent extra-label, human-drug, bulk-compounding, export-only, or otherwise unapproved animal-use source data; use only under veterinarian direction.

Medication Snapshot

Merged from the current Roxee medication system with field-level provenance, freshness, and completeness tracking.

Trazodone

Senvelgo (velagliflozin oral solution) is approved in cats for control of hyperglycemia associated with diabetes mellitus. Species commonly shown: Both.

Generic name
Trazodone
Brand names
Trazodone HCl
Manufacturer
Multiple FDA labelers
Species
Both
Completeness
81%
Validation
Incomplete
Brand names
Trazodone HCl

Indications / Uses

Senvelgo (velagliflozin oral solution) is approved in cats for control of hyperglycemia associated with diabetes mellitus.

Side Effects

Top reported reactions (openFDA): Vomiting, Diarrhoea, Lethargy (see also Central nervous system depression in Neurological), Decreased appetite, Death by euthanasia, Not eating.

FAQ

Both

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Pet Owner Quick Guide

Start here first for the safest next-step summary before the deeper medication detail.

Roxee still has limited plain-language guidance for this medication. Use the official documents and your veterinarian's instructions for product-specific details.

Used for:

Your vet decides this. Here's what owners typically ask/watch for.

Dosing note:

Exact dosing depends on your pet's species, weight, and health status. Use your veterinarian's instructions for the exact dose and schedule.

What to watch for:

  • Hair loss (1 reports)
  • Elevated temperature (1 reports)
  • Elevated symmetrical dimethylarginine (1 reports)

When to call the vet:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
  • Facial swelling or hives.
  • Blood in vomit or stool.

What to tell or ask your vet today:

  • Is this medicine the right fit for my pet’s current symptoms?
  • Which warning signs mean I should call back right away?
  • How should I handle missed doses or refusal to take the medicine?
Major cautions & emergency warning signs

Side effects to monitor:

  • Hair loss
  • Elevated temperature
  • Elevated symmetrical dimethylarginine

Most reported reactions:

  • Hair loss (1 reports)
  • Elevated temperature (1 reports)
  • Elevated symmetrical dimethylarginine (1 reports)

Emergency warning signs:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
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Quick Facts

Official label facts first, then secondary summaries. Marketing content is separated below.

Species: Both
Manufacturer: Multiple FDA labelers
Identifiers:
NDC Package: 73309-317-01 NDC Package: 73309-317-02 NDC Package: 73377-170-01 NDC Package: 73377-170-02 NDC Product: 73309 NDC Product: 73377

Adverse Reactions

Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.

Tap or hover a reaction to see what it means in plain language.

Tracked signals
32
Reported cases
32
Serious reports
21
Species represented
2
Grouped by Body System
Digestive (1) · Diarrhea Skin & allergy (1) · Hair loss Neurologic (2) · Unsteady walking (ataxia), Convulsion Behavior (1) · Behavioral disorder (unspecified) Other (27) · Eosinopenia, Elevated temperature, Elevated symmetrical dimethylarginine
Most Reported Reactions
Reaction Body system Cases Species Serious cases
Skin & allergy 1 Cat 1
Other 1 Dog 1
Other 1 Dog 1
Other 1 Dog 1
Other 1 Dog 1
Other 1 Dog 1
Other 1 Dog 1
Other 1 Dog 1

Species coverage: Dog (23) Cat (9)

View detailed reaction table
Reaction Body system Species Seriousness Frequency Reports
Neurologic Cat Non-serious - 1
Skin & allergy Cat Serious - 1
Other Cat Non-serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Cat Non-serious - 1
Other Cat Non-serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Digestive Dog Non-serious - 1
Other Cat Non-serious - 1
Other Cat Non-serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Neurologic Dog Serious - 1
Other Cat Non-serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Behavior Dog Non-serious - 1
Other Dog Serious - 1
Other Cat Non-serious - 1
Other Dog Non-serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Source metadata:

Documents

Owner handouts and official technical documents open on-page first, with the original source still one click away.

Owner handouts

0
No owner handouts linked yet.

Official label / PI

0
No official label or package insert links yet.

SPL

2

FOI

0
No FOI links yet.

Trazodone HCl SPL

SPL · Structured Product Label

Open original
FDA Structured Product Label XML for Trazodone HCl. Use the source link for the full official labeling record.

Trazodone HCl SPL

SPL · Structured Product Label

Open original
FDA Structured Product Label XML for Trazodone HCl. Use the source link for the full official labeling record.
Source metadata:
Veterinary reference (advanced)

Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.

At a Glance

Quick facts and links to official labeling and safety signals.

Data freshness
  • Storefront facts: Source Roxee | Refreshed May 5, 2026, 10:05 AM UTC
    The storefront fact projection used for browse cards and quick facts.
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed May 5, 2026, 10:00 AM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
  • openFDA reaction terms: Source FDA openFDA | Refreshed May 5, 2026, 10:04 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed May 5, 2026, 10:04 AM UTC
Official (FDA)
Identity: Generic ingredient • FDA branded products available
Official FDA brands: Trazodone HCl
Manufacturer mapping: Multiple FDA labelers
Case-reported brands (openFDA): MSK
Catalog species: Both
NDC: Packages 73309-317-01 73309-317-02 73377-170-01 73377-170-02 • Products 73309 73377
Safety (openFDA)
Top reactions: Dog 34 • Cat 3 • View
Case summaries: 9 (showing 8) • View
openFDA reports are unverified and do not prove causation.
Diagnosis Codes

Diagnosis-code mappings are not available for this medication yet.

Counseling and Monitoring Highlights

Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.

Top reaction signals
Hair loss (1) Elevated temperature (1) Elevated symmetrical dimethylarginine (1) Elevated serum alkaline phosphatase (1) Elevated creatinine (1) Dilated pupils (1) Difficulty standing (1) Deafness (1)

Identifiers & Packages

Normalized identifiers (NDC/NADA/ANADA) and package metadata from regulator listings.

Identifiers
NDC Package: 73309-317-01 NDC Package: 73309-317-02 NDC Package: 73377-170-01 NDC Package: 73377-170-02 NDC Product: 73309 NDC Product: 73377
Package NDC Product NDC Form / Route Status
73309-317-01 73309 -
73309-317-02 73309 -
73377-170-01 73377 -
73377-170-02 73377 -

Enriched Documents

Documents are tiered by source trust: Official, Clinical, Manufacturer, Marketing.

  • Trazodone HCl SPL • Structured Product Label • Official
    FDA Structured Product Label from the electronic animal drug product listing directory.
  • Trazodone HCl SPL • Structured Product Label • Official
    FDA Structured Product Label from the electronic animal drug product listing directory.

Data Sources & Change Log

Every non-trivial field is expected to include provenance and update timestamps.

Official 29 Clinical 7 Manufacturer 0 Marketing 0
Current Field Facts
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-21)
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-20)
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-19)
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-17)
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-16)
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-16)
  • side_effects: Top reported reactions (openFDA): Vomiting, Diarrhoea, Lethargy (see also Central nervous system depression in Neurological), Decreased appetite, Death by euth… (Clinical, 2026-04-11)
  • manufacturer_name: Multiple FDA labelers (Official, 2026-05-05)
  • manufacturer_name: Multiple FDA labelers (Official, 2026-05-03)
  • manufacturer_name: Multiple FDA labelers (Official, 2026-05-02)
  • manufacturer_name: Multiple FDA labelers (Official, 2026-04-29)
  • manufacturer_name: Multiple FDA labelers (Official, 2026-04-28)
  • manufacturer_name: Multiple FDA labelers (Official, 2026-04-27)
  • manufacturer_name: Multiple FDA labelers (Official, 2026-04-26)
  • manufacturer_name: Multiple FDA labelers (Official, 2026-04-25)
  • manufacturer_name: Multiple FDA labelers (Official, 2026-04-22)
  • side_effects: Top reported reactions (openFDA): Vomiting, Diarrhoea, Lethargy (see also Central nervous system depression in Neurological), Decreased appetite, Death by euth… (Official, 2026-05-05)
  • side_effects: Top reported reactions (openFDA): Vomiting, Diarrhoea, Lethargy (see also Central nervous system depression in Neurological), Decreased appetite, Death by euth… (Official, 2026-05-03)
  • side_effects: Top reported reactions (openFDA): Vomiting, Diarrhoea, Lethargy (see also Central nervous system depression in Neurological), Decreased appetite, Death by euth… (Official, 2026-04-30)
  • side_effects: Top reported reactions (openFDA): Vomiting, Diarrhoea, Lethargy (see also Central nervous system depression in Neurological), Decreased appetite, Death by euth… (Official, 2026-04-29)
Recent Revisions
  • side_effects updated 2026-05-05 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-05-03 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-04-30 10:09 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-04-29 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-04-28 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-04-27 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-04-26 10:06 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-04-25 10:05 by etl_backfill • Backfilled from existing medication fields
  • monitoring updated 2026-04-21 10:07 by curated_loader • Clinical monitoring context for feline diabetes management.
  • usage updated 2026-04-21 10:07 by curated_loader • Usage statement from FDA warning letter and approved-product context.
  • drug_profile_type updated 2026-04-21 10:07 by curated_loader • FDA source confirms Senvelgo as a branded approved product.
  • manufacturer_name updated 2026-04-21 10:07 by curated_loader • FDA warning letter identifies the approved sponsor/manufacturer.
  • brand_names updated 2026-04-21 10:07 by curated_loader • FDA warning letter references Senvelgo as the approved animal drug.
  • approval_reference updated 2026-04-21 10:07 by curated_loader • Official FDA application reference for Senvelgo.
  • monitoring updated 2026-04-20 10:08 by curated_loader • Clinical monitoring context for feline diabetes management.
  • usage updated 2026-04-20 10:08 by curated_loader • Usage statement from FDA warning letter and approved-product context.
  • drug_profile_type updated 2026-04-20 10:08 by curated_loader • FDA source confirms Senvelgo as a branded approved product.
  • manufacturer_name updated 2026-04-20 10:08 by curated_loader • FDA warning letter identifies the approved sponsor/manufacturer.
  • brand_names updated 2026-04-20 10:08 by curated_loader • FDA warning letter references Senvelgo as the approved animal drug.
  • approval_reference updated 2026-04-20 10:08 by curated_loader • Official FDA application reference for Senvelgo.

FDA Products & Applications (Animal Drugs @ FDA)

Official sponsor/proprietary-name/application-status records linked by active ingredient.

Product Sponsor Application Status Published

Data source: FDA Animal Drugs @ FDA (public search export).

Top Reported Reactions (openFDA)

De-duplicated reaction terms grouped by body system from FDA openFDA reports (not verified; does not prove causation).

Digestive
Diarrhea (1) • Dog

Showing top 5 for Digestive.

Skin & allergy
Hair loss (1) • Cat

Showing top 5 for Skin & allergy.

Neurologic
Unsteady walking (1) • Cat Convulsion (1) • Dog

Showing top 5 for Neurologic.

Behavior
Behavioral disorder (1) • Dog

Showing top 5 for Behavior.

Other
Eosinopenia (1) • Cat Elevated temperature (1) • Dog Elevated symmetrical dimethylarginine (1) • Dog Elevated serum alkaline phosphatase (1) • Dog Elevated creatinine (1) • Dog
Show more (22)
Elevated creatine-kinase (1) • Cat Elevated blood urea nitrogen (1) • Cat Dilated pupils (1) • Dog Difficulty standing (1) • Dog Delayed healing (1) • Cat Death (1) • Cat Deafness (1) • Dog Cyanotic mucous membranes (1) • Dog Constricted pupils (1) • Cat Confusion (1) • Dog Coma (1) • Dog Collapse NOS (1) • Dog Colitis (1) • Dog Cellulitis (1) • Dog Cardiorespiratory arrest (1) • Dog Bradycardia (1) • Dog Asystole (1) • Dog Aspiration pneumonia (1) • Cat Anaemia NOS (1) • Dog Agitation (1) • Dog Abnormal radiograph finding (1) • Dog Abnormal menace reflex test (1) • Dog

Showing top 5 for Other.

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Adverse Event Case Summaries (openFDA)

These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.

Dog, ['Retriever (unspecified)', 'Dog (unknown)'], Male, 12 year, 30.754 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Not eating, Wobbliness, Tiredness (lethargy) • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-075395
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 12.00 Year
  • Weight: 30.754 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Unassigned
Reactions Reported:
Not eating Wobbliness Tiredness (lethargy)
Outcomes: Ongoing

Dog, ['Beagle', 'Dog (unknown)'], Male, 3.5 year, 14.061 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Tiredness (lethargy), Agitation, Seizure NOS, Elevated symmetrical dimethylarginine, Falling… • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-074457
  • Serious AE: Yes
  • Treated For AE: No
  • Sex: Male
  • Age: 3.50 Year
  • Weight: 14.061 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Unassigned
Reactions Reported:
Tiredness (lethargy) Agitation Seizure NOS Elevated symmetrical dimethylarginine Falling Stiffness NOS Confusion Shivering
Outcomes: Outcome Unknown

Dog, Shepherd Dog - German, Male, 10 year, 38.555 kilogram • Drug: MSK, Unassigned, Oral • Reactions: Limb weakness, Hind limb ataxia, Proprioception deficit, Difficulty standing, Hind limb paresis… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-074384
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 10.00 Year
  • Weight: 38.555 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Unassigned
Reactions Reported:
Limb weakness Hind limb ataxia Proprioception deficit Difficulty standing Hind limb paresis Loose stool Not himself/herself Elevated serum alkaline phosphatase Elevated creatinine Colitis Spondylosis Abnormal radiograph finding
Outcomes: Ongoing

Dog, ['Retriever - Golden', 'Poodle - Standard'], Male, 8 year, 46 kilogram • Drug: MSK, Oral • Reactions: Seizure NOS, Rough recovery • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2025-US-074439
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 8.00 Year
  • Weight: 46.000 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
Reactions Reported:
Seizure NOS Rough recovery
Outcomes: Recovered/Normal

Dog, Retriever - Labrador, Female, 13 year, 34.428 kilogram • Drug: MSK, Unassigned, Unknown, Dose: 200 Milligram per animal • Reactions: Tiredness (lethargy), Unable to stand, Weakness • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-072887
  • Serious AE: No
  • Treated For AE: No
  • Sex: Female
  • Age: 13.00 Year
  • Weight: 34.428 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Unassigned
  • Dose: 200 Milligram per animal
Reactions Reported:
Tiredness (lethargy) Unable to stand Weakness
Outcomes: Ongoing

Dog, Pug, Male, 7 year, 9.979 kilogram • Drug: MSK, Oral, Dose: 75 Milligram per dose, Frequency: 1 per day • Reactions: Deafness • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-072217
  • Serious AE: Yes
  • Treated For AE: No
  • Sex: Male
  • Age: 7.00 Year
  • Weight: 9.979 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Dose: 75 Milligram per dose
  • Frequency: 1 per day
Reactions Reported:
Deafness
Outcomes: Outcome Unknown

Dog, Dog (unknown), Male, 11 year, 19.3 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Musculoskeletal disorder NOS, Walking difficulty • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-070411
  • Serious AE: No
  • Treated For AE: No
  • Sex: Male
  • Age: 11.00 Year
  • Weight: 19.300 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Unassigned
Reactions Reported:
Musculoskeletal disorder NOS Walking difficulty
Outcomes: Ongoing

Dog, Boxer (German Boxer), Female, 10 year, 30.844 kilogram • Drug: MSK, Tablet, Oral, Dose: 150 Milligram per dose, Frequency: 12 per hour • Reactions: Collapse NOS, Bradycardia, Paddling, Lateral recumbency, Reduced responses… • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2025-US-069345
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 10.00 Year
  • Weight: 30.844 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet
  • Dose: 150 Milligram per dose
  • Frequency: 12 per hour
Reactions Reported:
Collapse NOS Bradycardia Paddling Lateral recumbency Reduced responses Abnormal menace reflex test
Outcomes: Recovered/Normal

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Overdose Information

No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.

Storage & Handling

No approved storage guidance is linked yet for this ingredient. Use manufacturer packaging and veterinary guidance for handling/storage.

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