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Roxee Medication Guide

Water, Sodium Chloride, Sodium Lactate, Potassium Chloride, Calcium Chloride

Medication reference facts with explicit FDA-approval, off-label, source-limited, and safety context. Roxee does not sell, prescribe, or dispense medications.

Both Source review pending Source coverage pending Owner quick guide first
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Showing simplified owner view. Switch to Vet View for full technical detail.

Data freshness

Reference facts
Source review pending
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Roxee is still reviewing source support for this medication profile.

FDA applications
Regulatory match pending
No refresh timestamp yet

Roxee has safety or ingredient evidence for this medication, but a regulatory product/application match is still pending.

Safety reports
Safety data refreshed
May 30, 2026, 10:02 a.m.

openFDA reaction terms and case summaries are supporting evidence, not proof of causality.

Source timing details
Source timing details
  • Reference facts: Source Roxee | Refreshed Jun 22, 2026, 10:45 AM UTC
    The reference fact projection used for browse cards and quick facts.
  • openFDA reaction terms: Source FDA openFDA | Refreshed Jun 22, 2026, 10:45 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Jun 22, 2026, 10:45 AM UTC
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Water, Sodium Chloride, Sodium Lactate, Potassium Chloride, Calcium Chloride

Water, Sodium Chloride, Sodium Lactate, Potassium Chloride, Calcium Chloride

Drug type: Generic ingredient • Generic profile • Source coverage pending

Both 80% reference complete

Species: Both

Approval status: Source coverage pending. Roxee has limited supporting content for this record, but no on-page official FDA animal-drug document is linked yet. Treat it as source-limited until the ETL backfill adds official coverage.

Medication Snapshot

Merged from the current Roxee medication system with field-level provenance, freshness, and completeness tracking.

Water, Sodium Chloride, Sodium Lactate, Potassium Chloride, Calcium Chloride

Senvelgo (velagliflozin oral solution) is approved in cats for control of hyperglycemia associated with diabetes mellitus. Species commonly shown: Both.

Generic name
Water, Sodium Chloride, Sodium Lactate, Potassium Chloride, Calcium Chloride
Species
Both
Completeness
80%
Validation
Incomplete

Indications / Uses

Senvelgo (velagliflozin oral solution) is approved in cats for control of hyperglycemia associated with diabetes mellitus.

Side Effects

Top reported reactions (openFDA): Pain NOS, Death by euthanasia, Injection site pain, Elevated alanine aminotransferase (ALT), Hyperthermia, Vomiting.

FAQ

Both

Source Transparency

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Pet Owner Quick Guide

Start here first for the safest next-step summary before the deeper medication detail.

Roxee still has limited plain-language guidance for this medication. Use the official documents and your veterinarian's instructions for product-specific details.

Used for:

Your vet decides this. Here's what owners typically ask/watch for.

Dosing note:

Exact dosing depends on your pet's species, weight, and health status. Use your veterinarian's instructions for the exact dose and schedule.

What to watch for:

  • Bradycardia (1 reports)
  • Blood in vomit (1 reports)
  • Blepharospasm (1 reports)

When to call the vet:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
  • Facial swelling or hives.
  • Blood in vomit or stool.

What to tell or ask your vet today:

  • Is this medicine the right fit for my pet’s current symptoms?
  • Which warning signs mean I should call back right away?
  • How should I handle missed doses or refusal to take the medicine?

Next actions

Talk to a Vet / Find a Vet Near You Save to pet meds Share page Review report evidence
Research brief

Medication Research Insights

A source-aware map of what to know, what is uncertain, and what to verify with your veterinarian.

Source Backed Signals

What to know

Evidence-backed context Limited

Roxee has limited cited overview evidence for Water, Sodium Chloride, Sodium Lactate, Potassium Chloride, Calcium Chloride; use the official documents and your veterinarian's instructions for product-specific decisions.

Source: openFDA case USA-USFDACVM-2025-US-072073
Safety signal coverage Reported signals

32 tracked reaction signals; 32 reported cases; 28 serious reports; 2 species groups. These are reporting and label-derived signals for interpretation with a veterinarian.

Source: openFDA case USA-USFDACVM-2025-US-072073
Interpretation guardrail Not causation

Adverse-event reports help form a watch list, but they do not prove the medication caused the reaction and they are not a risk ranking between medications.

Evidence tension

Stronger signal Label / review

Official labels, package inserts, and reviewed summaries carry more weight than isolated reports.

Source: openFDA case USA-USFDACVM-2025-US-072073
Weaker signal Reported data

Case reports and openFDA terms are useful for pattern awareness, but they are incomplete, can include multiple exposures, and do not estimate an individual pet's probability of harm.

Reaction signal map

Most reported reactions Top terms

Bradycardia (1 reports), Blood in vomit (1 reports), Blepharospasm (1 reports), Bilirubinuria (1 reports), Behavioral disorder (unspecified) (1 reports)

Body systems represented Signal grouping

Digestive (4), Behavior (1), Other (27)

Explore supporting adverse reports

Species and breed lens

Species represented in reports Species lens

Dog (18 reports), Cat (14 reports)

Breed metadata in reports Metadata only

Shih Tzu (1), Dachshund - Miniature (1), Boxer (German Boxer) (1), Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) (1). These are report metadata, not proof that a breed is at higher risk.

What your vet may verify

Fit for this patient Vet check

Verify whether Water, Sodium Chloride, Sodium Lactate, Potassium Chloride, Calcium Chloride fits the pet's species, current diagnosis, age, weight, organ status, pregnancy/lactation status, and concurrent medications.

Evidence limitations Evidence review

Separate label-backed warnings from adverse-event reports and owner observations before changing the plan.

What to watch next

Watch list Owner-safe

Bradycardia, Blood in vomit, Blepharospasm

Call sooner if Escalation

Repeated vomiting or diarrhea. Severe lethargy (hard to wake, very low energy). Collapse or fainting.

Bottom line: Use this Water, Sodium Chloride, Sodium Lactate, Potassium Chloride, Calcium Chloride brief as a structured watch list and source map, not as a reason to start, stop, or change treatment without your veterinarian.
Vet source depth
  1. openFDA case USA-USFDACVM-2025-US-072073 · adverse_reaction · adverse reactions

Evidence

Review status / Updated / Sources

Review status: Clinical reviewer not listed

Updated: April 15, 2026, 10:04 AM UTC

Sources:
Safety & side effects

Side effects to monitor:

  • Bradycardia
  • Blood in vomit
  • Blepharospasm

Most reported reactions:

  • Bradycardia (1 reports)
  • Blood in vomit (1 reports)
  • Blepharospasm (1 reports)
Explore reported case details

Emergency warning signs:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
Talk to a Vet / Find a Vet Near You Start Symptom Intake

Vet Fast Scan

Source-backed clinical checkpoints for quick review.

FDA-labeled species
Not linked yet
Indication / use
Your vet decides this. Here's what owners typically ask/watch for.
Form / route / dose
Confirm product label and patient-specific plan.
Warnings
No structured warnings linked yet.
Adverse-event caveat
openFDA adverse-event cases are reported signals. They are not verified, do not prove causation, and do not estimate a pet's individual risk.
Source docs
No source documents linked yet.

Quick Facts

Official label facts first, then secondary summaries. Marketing content is separated below.

Species: Both
Manufacturer: Manufacturer not confirmed

Adverse Reactions

Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.

Reported case explorer

Filter stored openFDA reports by pet and report attributes. Counts describe reports in this data set, not risk.

Clear filters
openFDA adverse-event cases are reported signals. They are not verified, do not prove causation, and do not estimate a pet's individual risk.
Stored reports
4
Matching reports
0
Active filters
2
Selected filters
Reaction: Anaphylaxis Clear Body system: Neurologic Clear
Reset
Drill into common report signals
Lateral recumbency (2) Abdominal discomfort (1) Abnormal menace reflex test (1) Anaphylaxis (1) Other (4) Digestive (2) Effectiveness (1) Neurologic (1)
No stored openFDA reports match the selected filters. openFDA adverse-event cases are reported signals. They are not verified, do not prove causation, and do not estimate a pet's individual risk.

Tap or hover a reaction to see what it means in plain language.

Tracked signals
32
Reported cases
32
Serious reports
28
Species represented
2
Grouped by Body System
Digestive (4) · Loss of appetite, Bloody diarrhoea, Blood in vomit Behavior (1) · Behavioral disorder (unspecified) Other (27) · Bradycardia, Blepharospasm, Bilirubinuria
Most Reported Reactions
Reaction Body system Cases Species Serious cases
Other 1 Dog 1
Digestive 1 Cat 1
Other 1 Dog 1
Other 1 Dog 1
Behavior 1 Cat 1
Other 1 Cat 1
Other 1 Cat 1
Other 1 Cat 1

Species coverage: Dog (18) Cat (14)

View detailed reaction table
Reaction Body system Species Seriousness Frequency Reports
Digestive Dog Non-serious - 1
Other Dog Serious - 1
Digestive Dog Non-serious - 1
Digestive Cat Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Behavior Cat Serious - 1
Other Dog Non-serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Digestive Dog Serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Non-serious - 1
Source metadata:
Veterinary reference (advanced)

Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.

At a Glance

Quick facts and links to official labeling and safety signals.

Data freshness
  • Reference facts: Source Roxee | Refreshed Jun 22, 2026, 10:45 AM UTC
    The reference fact projection used for browse cards and quick facts.
  • openFDA reaction terms: Source FDA openFDA | Refreshed Jun 22, 2026, 10:45 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Jun 22, 2026, 10:45 AM UTC
Official (FDA)
Identity: Generic ingredient • No FDA branded products linked
No official FDA brand rows linked yet for this ingredient.
Case-reported brands (openFDA): MSK
Catalog species: Both
Safety (openFDA)
Top reactions: Dog 22 • Cat 0 • View
Case summaries: 4 (showing 4) • View
openFDA reports are unverified and do not prove causation.
Diagnosis Codes

Diagnosis-code mappings are not available for this medication yet.

Counseling and Monitoring Highlights

Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.

Top reaction signals
Bradycardia (1) Blood in vomit (1) Blepharospasm (1) Bilirubinuria (1) Behavioral disorder (unspecified) (1) Azotaemia (1) Atelectasis (1) Asphyxia (1)

Data Sources & Change Log

Every non-trivial field is expected to include provenance and update timestamps.

Official 70 Clinical 8 Manufacturer 0 Marketing 0
Current Field Facts
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-21)
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-20)
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-19)
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-17)
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-16)
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-16)
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-15)
  • side_effects: Top reported reactions (openFDA): Pain NOS, Death by euthanasia, Injection site pain, Elevated alanine aminotransferase (ALT), Hyperthermia, Vomiting. (Clinical, 2026-04-11)
  • side_effects: Top reported reactions (openFDA): Pain NOS, Death by euthanasia, Injection site pain, Elevated alanine aminotransferase (ALT), Hyperthermia, Vomiting. (Official, 2026-06-22)
  • side_effects: Top reported reactions (openFDA): Pain NOS, Death by euthanasia, Injection site pain, Elevated alanine aminotransferase (ALT), Hyperthermia, Vomiting. (Official, 2026-06-22)
  • side_effects: Top reported reactions (openFDA): Pain NOS, Death by euthanasia, Injection site pain, Elevated alanine aminotransferase (ALT), Hyperthermia, Vomiting. (Official, 2026-06-21)
  • side_effects: Top reported reactions (openFDA): Pain NOS, Death by euthanasia, Injection site pain, Elevated alanine aminotransferase (ALT), Hyperthermia, Vomiting. (Official, 2026-06-20)
  • side_effects: Top reported reactions (openFDA): Pain NOS, Death by euthanasia, Injection site pain, Elevated alanine aminotransferase (ALT), Hyperthermia, Vomiting. (Official, 2026-06-13)
  • side_effects: Top reported reactions (openFDA): Pain NOS, Death by euthanasia, Injection site pain, Elevated alanine aminotransferase (ALT), Hyperthermia, Vomiting. (Official, 2026-06-12)
  • side_effects: Top reported reactions (openFDA): Pain NOS, Death by euthanasia, Injection site pain, Elevated alanine aminotransferase (ALT), Hyperthermia, Vomiting. (Official, 2026-06-12)
  • side_effects: Top reported reactions (openFDA): Pain NOS, Death by euthanasia, Injection site pain, Elevated alanine aminotransferase (ALT), Hyperthermia, Vomiting. (Official, 2026-06-11)
  • side_effects: Top reported reactions (openFDA): Pain NOS, Death by euthanasia, Injection site pain, Elevated alanine aminotransferase (ALT), Hyperthermia, Vomiting. (Official, 2026-06-11)
  • side_effects: Top reported reactions (openFDA): Pain NOS, Death by euthanasia, Injection site pain, Elevated alanine aminotransferase (ALT), Hyperthermia, Vomiting. (Official, 2026-06-10)
  • side_effects: Top reported reactions (openFDA): Pain NOS, Death by euthanasia, Injection site pain, Elevated alanine aminotransferase (ALT), Hyperthermia, Vomiting. (Official, 2026-06-08)
  • side_effects: Top reported reactions (openFDA): Pain NOS, Death by euthanasia, Injection site pain, Elevated alanine aminotransferase (ALT), Hyperthermia, Vomiting. (Official, 2026-06-07)
Recent Revisions
  • side_effects updated 2026-06-22 10:45 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-06-22 10:04 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-06-21 05:18 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-06-20 20:58 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-06-13 11:33 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-06-12 10:42 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-06-12 10:04 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-06-11 19:22 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-06-11 18:40 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-06-10 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-06-08 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-06-07 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-06-06 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-06-05 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-06-04 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-06-03 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-06-02 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-06-01 10:40 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-06-01 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-05-31 10:05 by etl_backfill • Backfilled from existing medication fields

Top Reported Reactions (openFDA)

De-duplicated reaction terms grouped by body system from FDA openFDA reports (not verified; does not prove causation).

Digestive
Loss of appetite (1) • Dog Bloody diarrhoea (1) • Dog Blood in vomit (1) • Cat Appetite loss (1) • Dog

Showing top 5 for Digestive.

Behavior
Behavioral disorder (1) • Cat

Showing top 5 for Behavior.

Other
Bradycardia (1) • Dog Blepharospasm (1) • Dog Bilirubinuria (1) • Dog Bacterial skin infection NOS (1) • Dog Azotaemia (1) • Cat
Show more (22)
Atelectasis (1) • Cat Asphyxia (1) • Cat Arched back (1) • Cat Anaphylaxis (1) • Dog Anaemia NOS (1) • Cat Adrenal gland disorder NOS (1) • Dog Acute renal failure (1) • Dog Acidic urine (1) • Cat Acid-base disorder (1) • Cat Accidental exposure (1) • Cat Abnormal ultrasound finding (1) • Cat Abnormal stool colouration (1) • Dog Abnormal red blood cell (1) • Cat Abnormal radiograph finding (1) • Cat Abnormal posture NOS (1) • Dog Abnormal menace reflex test (1) • Dog Abnormal electrocardiogram (1) • Dog Abnormal breathing (1) • Cat Abdominal pain (1) • Dog Abdominal mass (1) • Dog Abdominal effusion (1) • Dog Abdominal discomfort (1) • Dog

Showing top 5 for Other.

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Adverse Event Case Summaries (openFDA)

These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.

Dog, Shih Tzu, Female, 1 year, 4.536 kilogram • Drug: MSK, Injection, Intravenous, Dose: 20 meq per l, Frequency: 1 per hour • Reactions: Necrotic wound, Skin lesion NOS, Local erythema, Loss of appetite, Diarrhea… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-072073
  • Serious AE: No
  • Treated For AE: Yes
  • Sex: Female
  • Age: 1.00 Year
  • Weight: 4.536 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Intravenous
  • Form: Injection
  • Dose: 20 meq per l
  • Frequency: 1 per hour
Reactions Reported:
Necrotic wound Skin lesion NOS Local erythema Loss of appetite Diarrhea Abdominal discomfort Dehydration Bacterial skin infection NOS
Outcomes: Ongoing

Dog, Dachshund - Miniature, Female, 4 year, 5.557 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Vomiting, Lateral recumbency, Pale mucous membrane, Dry mucous membrane, Anaphylaxis… • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2025-US-070459
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 4.00 Year
  • Weight: 5.557 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Unassigned
Reactions Reported:
Vomiting Lateral recumbency Pale mucous membrane Dry mucous membrane Anaphylaxis Hives Swollen muzzle
Outcomes: Recovered/Normal

Dog, Boxer (German Boxer), Female, 10 year, 30.844 kilogram • Drug: MSK, Injection, Intravenous, Dose: 20 meq per other, Frequency: 1 per hour • Reactions: Collapse NOS, Bradycardia, Paddling, Lateral recumbency, Reduced responses… • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2025-US-069345
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 10.00 Year
  • Weight: 30.844 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Intravenous
  • Form: Injection
  • Dose: 20 meq per other
  • Frequency: 1 per hour
Reactions Reported:
Collapse NOS Bradycardia Paddling Lateral recumbency Reduced responses Abnormal menace reflex test
Outcomes: Recovered/Normal

Dog, Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog), Female, 10 year, 25.855 kilogram • Drug: MSK, Liquid, Auricular (Otic) • Reactions: Deafness, Lack of efficacy (bacteria) - NOS • Outcome: Recovered with Sequela

  • Report ID: USA-USFDACVM-2025-US-063369
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 10.00 Year
  • Weight: 25.855 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Auricular (Otic)
  • Form: Liquid
Reactions Reported:
Deafness Lack of efficacy (bacteria) - NOS
Outcomes: Recovered with Sequela

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Overdose Information

No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.

Storage & Handling

No approved storage guidance is linked yet for this ingredient. Use manufacturer packaging and veterinary guidance for handling/storage.

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This medication has not been reviewed by a veterinarian yet.