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Roxee Medication Guide

Xylazine

Medication reference facts with explicit FDA-approval, off-label, source-limited, and safety context. Roxee does not sell, prescribe, or dispense medications.

Both Reference complete FDA data linked Rx required Liquid (Solution) Multiple FDA labelers Official label facts Owner quick guide first
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Data freshness

Reference facts
Reference refreshed
Aug 6, 2026, 7:47 p.m.

These are the reference facts Roxee uses on browse cards and quick facts.

FDA applications
FDA application data refreshed
Aug 6, 2026, 7:47 p.m.

Sponsor, product, and application records imported from Animal Drugs @ FDA.

Safety reports
Safety data refreshed
Aug 6, 2026, 7:49 p.m.

openFDA reaction terms and case summaries are supporting evidence, not proof of causality.

Source timing details
Source timing details
  • Reference facts: Source Roxee | Refreshed Aug 6, 2026, 7:47 PM UTC
    The reference fact projection used for browse cards and quick facts.
  • Animal Drugs @ FDA: Source FDA | Refreshed Aug 6, 2026, 7:47 PM UTC
    Applications/products are imported from FDA export data.
  • Animal Drugs @ FDA previews: Source FDA | Refreshed Feb 9, 2026, 3:05 AM UTC
    Label highlights/doc links are fetched from FDA preview endpoints.
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed Aug 6, 2026, 7:47 PM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
  • openFDA reaction terms: Source FDA openFDA | Refreshed Aug 6, 2026, 7:52 PM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Aug 6, 2026, 7:52 PM UTC
Illustration placeholder
Xylazine

Xylazine

Drug type: Generic ingredient • Branded profile • FDA branded products available

Both Liquid (Solution) Rx required 100% reference complete

Species: Both

Manufacturer: Multiple FDA labelers

Medication Snapshot

Merged from the current Roxee medication system with field-level provenance, freshness, and completeness tracking.

Xylazine

To produce sedation, as an analgesic, and as a preanesthetic to local or general anesthesia. To produce sedation, as an analgesic, and as a preanesthetic to local anesthesia. To produce sedation, accompanied by a shorter period of analgesia. May be used to calm and facilitate handling of fractious animals for diagnostic procedures, for minor surgical procedures, for therapeutic medication for sedation and relief of pain following injury or surgery, and as a preanesthetic to local anesthetic. At the recommended dosages, can be used in conjunction with local anesthetics, such as procaine or lidocaine. To produce sedation, as an analgesic, and as a preanesthetic to local or general anesthesia Species commonly shown: Both, Dog, Horse, Not For Meat Production.

Generic name
Xylazine
Brand names
Anased®, Xylazine HCl Injection AnaSed® Equine Injection, Sedazine™, Chanazine®
Manufacturer
Multiple FDA labelers
Species
Both, Dog, Horse, Cat
Dosage forms
Liquid (Solution), Injectable Solution
Prescription
Prescription required
Completeness
100%
Validation
Complete
Brand names
Anased® Xylazine HCl Injection AnaSed® Equine Injection Sedazine™ Chanazine® XylaMed™ Rompun® Injectable (100 mg) Rompun® Injectable (20 mg) X Xylaxine Xylazine HCl Xylazine Hydrochloride Anased Xylazine Rompun
Dosage forms
Liquid (Solution) Injectable Solution

Indications / Uses

To produce sedation, as an analgesic, and as a preanesthetic to local or general anesthesia. To produce sedation, as an analgesic, and as a preanesthetic to local anesthesia. To produce sedation, accompanied by a shorter period of analgesia. May be used to calm and facilitate handling of fractious animals for diagnostic procedures, for minor surgical procedures, for therapeutic medication for sedation and relief of pain following injury or surgery, and as a preanesthetic to local anesthetic. At the recommended dosages, can be used in conjunction with local anesthetics, such as procaine or lidocaine. To produce sedation, as an analgesic, and as a preanesthetic to local or general anesthesia

Warnings / Contraindications

Federal law restricts this drug to use by or on the order of a licensed veterinarian. Do not use in horses intended for human consumption. Do not use in domestic food-producing animals. Do not use in Cervidae less than 15 days before or during the hunting season.

  • Federal law restricts this drug to use by or on the order of a licensed veterinarian. Do not use in horses intended for human consumption. Do not use in domestic food-producing animals. Do not use in Cervidae less than 15 days before or during the hunting season.

Side Effects

Top reported reactions (openFDA): Death, Lack of efficacy - NOS, Vomiting, Death by euthanasia, Hives (see also 'Skin'), INEFFECTIVE, ANESTHESIA.

FAQ

Both, Dog, Horse, Not For Meat Production, Cat, Fallow Deer, Excluding Use For Food, Elk, Excluding Use For Food, Mule Deer, Excluding Use For Food, Sika Deer, Excluding Use For Food, White-Tailed Deer, Excluding Use For Food

Yes. Roxee shows this as prescription-only.

Liquid (Solution), Injectable Solution

Related Conditions

Pain (acute, chronic)

Source Transparency

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Pet Owner Quick Guide

Start here first for the safest next-step summary before the deeper medication detail.

Used for:

To produce sedation, as an analgesic, and as a preanesthetic to local or general anesthesia.

Dosing note:

Exact dosing depends on your pet's species, weight, and health status. Use your veterinarian's instructions for the exact dose and schedule.

What to watch for:

  • Do not use in horses intended for human consumption
  • Do not use in Cervidae less than 15 days before or during the hunting season
  • Vomiting (1 reports)
  • Paraparesis (1 reports)
  • Panting (1 reports)

When to call the vet:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
  • Facial swelling or hives.
  • Blood in vomit or stool.

Regulatory restrictions are shown in Vet View.

What to tell or ask your vet today:

  • Is this medicine the right fit for my pet’s current symptoms?
  • Which warning signs mean I should call back right away?
  • How should I handle missed doses or refusal to take the medicine?

Next actions

Talk to a Vet / Find a Vet Near You Save to pet meds Share page Review report evidence
Research brief

Medication Research Insights

A source-aware map of what to know, what is uncertain, and what to verify with your veterinarian.

Source Backed Signals

What to know

Evidence-backed context Limited

Roxee has limited cited overview evidence for Xylazine; use the official documents and your veterinarian's instructions for product-specific decisions.

Source: openFDA case DEU-USFDACVM-2025-DE-000039
Safety signal coverage Reported signals

32 tracked reaction signals; 32 reported cases; 24 serious reports; 2 species groups. These are reporting and label-derived signals for interpretation with a veterinarian.

Source: openFDA case DEU-USFDACVM-2025-DE-000039
Interpretation guardrail Not causation

Adverse-event reports help form a watch list, but they do not prove the medication caused the reaction and they are not a risk ranking between medications.

Evidence tension

Stronger signal Label / review

Official labels, package inserts, and reviewed summaries carry more weight than isolated reports.

Source: openFDA case DEU-USFDACVM-2025-DE-000039
Weaker signal Reported data

Case reports and openFDA terms are useful for pattern awareness, but they are incomplete, can include multiple exposures, and do not estimate an individual pet's probability of harm.

Reaction signal map

Most reported reactions Top terms

Vomiting (1 reports), Paraparesis (1 reports), Panting (1 reports), Otitis NOS (1 reports), Myelopathy NOS (1 reports)

Body systems represented Signal grouping

Digestive (3), Effectiveness (1), Other (28)

Explore supporting adverse reports

Species and breed lens

Species represented in reports Species lens

Dog (17 reports), Cat (15 reports)

Breed metadata in reports Metadata only

Cat (unknown) (2), Domestic Shorthair (2), Greyhound (1), ['Retriever - Golden', 'Poodle - Standard'] (1). These are report metadata, not proof that a breed is at higher risk.

What your vet may verify

Fit for this patient Vet check

Verify whether Xylazine fits the pet's species, current diagnosis, age, weight, organ status, pregnancy/lactation status, and concurrent medications.

Evidence limitations Evidence review

Separate label-backed warnings from adverse-event reports and owner observations before changing the plan.

What to watch next

Watch list Owner-safe

Do not use in horses intended for human consumption, Do not use in Cervidae less than 15 days before or during the hunting season, Vomiting, Paraparesis, Panting

Call sooner if Escalation

Repeated vomiting or diarrhea. Severe lethargy (hard to wake, very low energy). Collapse or fainting.

Bottom line: Use this Xylazine brief as a structured watch list and source map, not as a reason to start, stop, or change treatment without your veterinarian.
Vet source depth
  1. openFDA case DEU-USFDACVM-2025-DE-000039 · adverse_reaction · adverse reactions
  2. Contraindication source · fda_animal_drugs · warnings contraindications
  3. FDA application profile · official_label · quick facts
  4. FDA application profile · official_label · quick facts
  5. Medication usage source · fda_animal_drugs · quick facts
  6. SPL · document · documents
  7. SPL · document · documents
  8. FOI · document · documents

Evidence

Review status / Updated / Sources

Review status: Clinical reviewer not listed

Updated: February 12, 2026, 10:44 PM UTC

Sources:
Safety & side effects

Side effects to monitor:

  • Do not use in horses intended for human consumption
  • Do not use in Cervidae less than 15 days before or during the hunting season
  • Vomiting
  • Paraparesis
  • Panting

Most reported reactions:

  • Vomiting (1 reports)
  • Paraparesis (1 reports)
  • Panting (1 reports)
Explore reported case details

Emergency warning signs:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
Talk to a Vet / Find a Vet Near You Start Symptom Intake

Vet Fast Scan

Source-backed clinical checkpoints for quick review.

FDA-labeled species
Cat, Dog, Elk, Fallow Deer, Horse, Mule Deer, Sika Deer, White-Tailed Deer
Indication / use
To produce sedation, as an analgesic, and as a preanesthetic to local or general anesthesia.
Form / route / dose
Form: Injectable Solution, Liquid (Solution)
Route: Intramuscular, Intravenous, Subcutaneous
Confirm product label and patient-specific plan.
Warnings
  • High: Federal law restricts this drug to use by or on the order of a licensed veterinarian. Do not use in horses intended for…
Adverse-event caveat
openFDA adverse-event cases are reported signals. They are not verified, do not prove causation, and do not estimate a pet's individual risk.
Source docs

Quick Facts

Official label facts first, then secondary summaries. Marketing content is separated below.

Species: Both
Manufacturer: Multiple FDA labelers
Form: Injectable Solution, Liquid (Solution)
Identifiers:
ANADA: 200088 ANADA: 200139 ANADA: 200184 ANADA: 200529 NADA: 139236 NADA: 140442 NADA: 47955 NADA: 47956 NDC Package: 11695-4024-1 NDC Package: 17033-099-05 NDC Package: 58597-8582-6 NDC Package: 58597-8582-8 NDC Package: 62157-373-01 NDC Package: 62157-374-01 NDC Package: 62991-1624-2 NDC Package: 62991-1624-3 NDC Package: 62991-1624-4 NDC Package: 63537-0091-5 NDC Package: 63537-0092-9 NDC Package: 64189-9001-0
Source metadata:

Warnings / Contraindications

Federal law restricts this drug to use by or on the order of a licensed veterinarian. Do not use in horses intended for human consumption. Do not use in domestic food-producing animals. Do not use in Cervidae less than 15 days before or during the hunting season.

  • High: Federal law restricts this drug to use by or on the order of a licensed veterinarian. Do not use in horses intended for human consumption. Do not use in domestic food-producing animals. Do not use in Cervidae less than 15 days before or during the hunting season.
Source metadata:

Adverse Reactions

Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.

Reported case explorer

Filter stored openFDA reports by pet and report attributes. Counts describe reports in this data set, not risk.

Clear filters
openFDA adverse-event cases are reported signals. They are not verified, do not prove causation, and do not estimate a pet's individual risk.
Stored reports
8
Matching reports
8
Active filters
0
Reset
Drill into common report signals
Lack of efficacy - NOS (5) Unrelated death (3) Death by euthanasia (1) Drooling (1) Effectiveness (5) Other (5) Digestive (1) Neurologic (1)
Showing up to 50 matching reports.

USA-USFDACVM-2026-US-009864

Received 2026-02-23 · MSK · MSK

Non-serious
Species
Cat
Breed
Cat (unknown)
Sex
Unknown Unknown
Region
USA
Reactions
NauseaDrooling
Body systems
Digestive
Outcomes
Recovered/Normal

USA-USFDACVM-2026-US-004923

Received 2026-02-04 · MSK · MSK

Non-serious
Species
Cat
Breed
Domestic Shorthair
Size / weight
Under 10 lb (4.33 Kilogram)
Age
Under 1 year (6 Month)
Sex
Male Neutered
Region
USA
Reactions
HallucinationHyperactivityFallingLocomotor disturbance
Body systems
Other
Outcomes
Ongoing

USA-USFDACVM-2025-US-075461

Received 2025-12-29 · MSK · MSK

Serious
Species
Dog
Breed
Greyhound
Size / weight
50-99 lb (27.3 Kilogram)
Age
8+ years (9 Year)
Sex
Female Neutered
Region
USA
Reactions
Lack of efficacy - NOSUnrelated death
Body systems
EffectivenessOther
Outcomes
Euthanized

USA-USFDACVM-2025-US-075440

Received 2025-12-29 · MSK · MSK

Serious
Species
Dog
Breed
['Retriever - Golden', 'Poodle - Standard']
Size / weight
50-99 lb (25.5 Kilogram)
Age
4-7 years (5 Year)
Sex
Male Neutered
Region
USA
Reactions
Lack of efficacy - NOSUnrelated death
Body systems
EffectivenessOther
Outcomes
Euthanized

USA-USFDACVM-2025-US-075367

Received 2025-12-29 · MSK · MSK

Serious
Species
Dog
Breed
Crossbred Canine/dog
Size / weight
25-49 lb (17.7 Kilogram)
Age
8+ years (14 Year)
Sex
Male Neutered
Region
USA
Reactions
Lack of efficacy - NOSUnrelated death
Body systems
EffectivenessOther
Outcomes
Euthanized

USA-USFDACVM-2025-US-071331

Received 2025-12-03 · MSK · MSK

Non-serious
Species
Dog
Breed
Dog (unknown)
Sex
Unknown Unknown
Region
USA
Reactions
Lack of efficacy - NOS
Body systems
Effectiveness
Outcomes
Recovered/Normal

USA-USFDACVM-2025-US-071320

Received 2025-12-03 · MSK · MSK

Non-serious
Species
Cat
Breed
Cat (unknown)
Sex
Unknown Unknown
Region
USA
Reactions
Lack of efficacy - NOS
Body systems
Effectiveness
Outcomes
Recovered/Normal

USA-USFDACVM-2025-US-072459

Received 2025-12-01 · MSK · MSK

Serious
Species
Cat
Breed
Domestic Shorthair
Size / weight
10-24 lb (4.536 Kilogram)
Age
1-3 years (2 Year)
Sex
Male Neutered
Region
USA
Reactions
Seizure NOSDeath by euthanasia
Body systems
NeurologicOther
Outcomes
Euthanized

Tap or hover a reaction to see what it means in plain language.

Tracked signals
32
Reported cases
32
Serious reports
24
Species represented
2
Grouped by Body System
Digestive (3) · Vomiting, Nausea, Drooling Effectiveness (1) · Lack of efficacy - NOS Other (28) · Paraparesis, Panting, Otitis NOS
Most Reported Reactions
Reaction Body system Cases Species Serious cases
Digestive 1 Dog 1
Other 1 Dog 1
Other 1 Dog 1
Other 1 Cat 1
Other 1 Dog 1
Other 1 Cat 1
Other 1 Dog 1
Other 1 Dog 1

Species coverage: Dog (17) Cat (15)

View detailed reaction table
Reaction Body system Species Seriousness Frequency Reports
Digestive Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Digestive Cat Non-serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Other Dog Serious - 1
Other Cat Non-serious - 1
Other Dog Serious - 1
Effectiveness Cat Non-serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Cat Non-serious - 1
Other Cat Serious - 1
Other Cat Non-serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Cat Non-serious - 1
Other Dog Non-serious - 1
Other Dog Serious - 1
Digestive Cat Non-serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Other Dog Serious - 1
Source metadata:

Source Documents

The most useful source links appear first; full previews and metadata stay in the veterinary/professional layer.

Use original documents to confirm product-specific warnings, ingredients, and handling details with your veterinarian.

Rompun® Injectable (100 mg) SPL · SPL Rompun® Injectable (20 mg) SPL · SPL Sedazine™ SPL · SPL

Full source previews and metadata remain in the veterinary/professional layer.

Owner handouts

0
No owner handouts linked yet.

Official label / PI

0
No official label or package insert links yet.

SPL

22

FOI

9

Rompun® Injectable (100 mg)

SPL · SPL

Open original
FDA Structured Product Label

Rompun® Injectable (100 mg)

Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.

Sponsor
Dechra Veterinary Products LLC
NADA
47956
Status
RX
Form
Liquid (Solution)
Route
Intramuscular, Intravenous, Subcutaneous
Species
Horse • Fallow Deer • Elk • Mule Deer • Sika Deer • White-Tailed Deer
Composition / specifications
Each milliliter of solution contains xylazine hydrochloride equivalent to 100 milligrams xylazine

Horses

Indication
To produce sedation, as an analgesic, and as a preanesthetic to local or general anesthesia.
Dosage
0.5 milligrams per pound intravenously or 1.0 milligram per pound intramuscularly.
Limitations

Do not use in horses intended for human consumption.

Fallow deer (Dama dama)

Indication
To produce sedation, as an analgesic, and as a preanesthetic to local anesthesia. To produce sedation, accompanied by a shorter period of analgesia. May be used to calm and facilitate handling of fractious animals for diagnostic procedures, for minor surgical procedures, for therapeutic medication for sedation and relief of pain following injury or surgery, and as a preanesthetic to local anesthetic. At the recommended dosages, can be used in conjunction with local anesthetics, such as procaine or lidocaine.
Dosage
Administer intramuscularly, by hand syringe, or by syringe dart, in the heavy muscles of the croup or shoulder 2 to 4 milligrams per pound.
Limitations
Do not use in domestic food-producing animals. Do not use in Cervidae less than 15 days before or during the hunting season.

Mule deer (Odocoileus hemionus), sika deer (Cervus nippon), and white-tailed deer (Odocoileus virginianus)

Indication
To produce sedation, as an analgesic, and as a preanesthetic to local anesthesia. To produce sedation, accompanied by a shorter period of analgesia. May be used to calm and facilitate handling of fractious animals for diagnostic procedures, for minor surgical procedures, for therapeutic medication for sedation and relief of pain following injury or surgery, and as a preanesthetic to local anesthetic. At the recommended dosages, can be used in conjunction with local anesthetics, such as procaine or lidocaine.
Dosage
Administer intramuscularly, by hand syringe, or by syringe dart, in the heavy muscles of the croup or shoulder 1 to 2 milligrams per pound.
Limitations
Do not use in domestic food-producing animals. Do not use in Cervidae less than 15 days before or during the hunting season.

Elk (Cervus canadensis)

Indication
To produce sedation, as an analgesic, and as a preanesthetic to local anesthesia. To produce sedation, accompanied by a shorter period of analgesia. May be used to calm and facilitate handling of fractious animals for diagnostic procedures, for minor surgical procedures, for therapeutic medication for sedation and relief of pain following injury or surgery, and as a preanesthetic to local anesthetic. At the recommended dosages, can be used in conjunction with local anesthetics, such as procaine or lidocaine.
Dosage
Administer intramuscularly, by hand syringe, or by syringe dart, in the heavy muscles of the croup or shoulder 0.25 to 0.5 milligrams per pound of body weight.
Limitations
Do not use in domestic food-producing animals. Do not use in Cervidae less than 15 days before or during the hunting season.

Rompun® Injectable (20 mg)

SPL · SPL

Open original
FDA Structured Product Label

Rompun® Injectable (20 mg)

Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.

Sponsor
Dechra Veterinary Products LLC
NADA
47955
Status
RX
Form
Liquid (Solution)
Route
Intravenous, Intramuscular, Subcutaneous
Species
Dog • Cat
Composition / specifications
Each milliliter of solution contains xylazine hydrochloride equivalent to 20 milligrams xylazine.

Cats

Indication
To produce sedation, as an analgesic, and as a preanesthetic to local or general anesthesia.
Dosage
0.5 milligrams per pound intravenously or 1.0 milligram per pound intramuscularly.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Dogs

Indication
To produce sedation, as an analgesic, and as a preanesthetic to local or general anesthesia.
Dosage
0.5 milligrams per pound intravenously or 1.0 milligram per pound intramuscularly.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Sedazine™

SPL · SPL

Open original
FDA Structured Product Label

Sedazine™

Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.

Sponsor
Boehringer Ingelheim Animal Health USA Inc.
ANADA
200-088
Status
RX
Form
Liquid (Solution)
Route
Intramuscular, Intravenous
Species
Horse • Fallow Deer • Elk • Mule Deer • Sika Deer • White-Tailed Deer
Composition / specifications
Each milliliter of solution contains xylazine hydrochloride equivalent to 100 milligrams xylazine or 300 milligrams xylazine.

Mule deer (Odocoileus hemionus), sika deer (Cervus nippon), and white-tailed deer (Odocoileus virginianus)

Indication
To produce sedation, as an analgesic, and as a preanesthetic to local anesthesia. To produce sedation, accompanied by a shorter period of analgesia. May be used to calm and facilitate handling of fractious animals for diagnostic procedures, for minor surgical procedures, for therapeutic medication for sedation and relief of pain following injury or surgery, and as a preanesthetic to local anesthetic. At the recommended dosages, can be used in conjunction with local anesthetics, such as procaine or lidocaine.
Dosage
Administer intramuscularly, by hand syringe, or by syringe dart, in the heavy muscles of the croup or shoulder 1 to 2 milligrams per pound.
Limitations
Do not use in domestic food-producing animals. Do not use in Cervidae less than 15 days before or during the hunting season.

Elk (Cervus canadensis)

Indication
To produce sedation, as an analgesic, and as a preanesthetic to local anesthesia. To produce sedation, accompanied by a shorter period of analgesia. May be used to calm and facilitate handling of fractious animals for diagnostic procedures, for minor surgical procedures, for therapeutic medication for sedation and relief of pain following injury or surgery, and as a preanesthetic to local anesthetic. At the recommended dosages, can be used in conjunction with local anesthetics, such as procaine or lidocaine.
Dosage
Administer intramuscularly, by hand syringe, or by syringe dart, in the heavy muscles of the croup or shoulder 0.25 to 0.5 milligrams per pound of body weight.
Limitations
Do not use in domestic food-producing animals. Do not use in Cervidae less than 15 days before or during the hunting season.

Fallow deer (Dama dama)

Indication
To produce sedation, as an analgesic, and as a preanesthetic to local anesthesia. To produce sedation, accompanied by a shorter period of analgesia. May be used to calm and facilitate handling of fractious animals for diagnostic procedures, for minor surgical procedures, for therapeutic medication for sedation and relief of pain following injury or surgery, and as a preanesthetic to local anesthetic. At the recommended dosages, can be used in conjunction with local anesthetics, such as procaine or lidocaine.
Dosage
Administer intramuscularly, by hand syringe, or by syringe dart, in the heavy muscles of the croup or shoulder 2 to 4 milligrams per pound.
Limitations
Do not use in domestic food-producing animals. Do not use in Cervidae less than 15 days before or during the hunting season.

Horses

Indication
To produce sedation, as an analgesic, and as a preanesthetic to local or general anesthesia
Dosage
0.5 milligrams per pound intravenously or 1.0 milligram per pound intramuscularly.
Limitations
Not for use in horses intended for food..

Xylazine HCl Injection

SPL · SPL

Open original
FDA Structured Product Label

Xylazine HCl Injection AnaSed® Equine Injection

Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.

Sponsor
Cronus Pharma Specialities India Private Ltd.
NADA
140-442
Status
RX
Form
Injectable Solution
Route
Intramuscular, Intravenous
Species
Horse
Composition / specifications
Each milliliter of solution contains xylazine hydrochloride equivalent to 100 milligrams of xylazine .

Horses

Indication
To produce sedation, as an analgesic, and as a preanesthetic to local or general anesthesia.
Dosage
0.5 milligrams per pound intravenously or 1.0 milligrams per pound intramuscularly.
Limitations

Do not use in horses intended for human consumption.

AnaSed® Equine Injection

SPL · SPL

Open original
FDA Structured Product Label

Xylazine HCl Injection AnaSed® Equine Injection

Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.

Sponsor
Cronus Pharma Specialities India Private Ltd.
NADA
140-442
Status
RX
Form
Injectable Solution
Route
Intramuscular, Intravenous
Species
Horse
Composition / specifications
Each milliliter of solution contains xylazine hydrochloride equivalent to 100 milligrams of xylazine .

Horses

Indication
To produce sedation, as an analgesic, and as a preanesthetic to local or general anesthesia.
Dosage
0.5 milligrams per pound intravenously or 1.0 milligrams per pound intramuscularly.
Limitations

Do not use in horses intended for human consumption.

Anased®

SPL · SPL

Open original
FDA Structured Product Label

Anased®

Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.

Sponsor
Cronus Pharma Specialities India Private Ltd.
NADA
139-236
Status
RX
Form
Liquid (Solution)
Route
Subcutaneous, Intramuscular, Intravenous
Species
Dog • Horse • Cat • Fallow Deer • Elk • Mule Deer • Sika Deer • White-Tailed Deer
Composition / specifications
Each milliliter of solution contains xylazine hydrochloride equivalent to: 1) 20 milligrams xylazine, 2) 100 milligrams xylazine or 3) 300 milligrams xylazine.

Dogs

Indication
To produce sedation, as an analgesic, and as a preanesthetic to local or general anesthesia.
Dosage
0.5 milligrams per pound intravenously or 1.0 milligram per pound intramuscularly.

Horses

Indication
To produce sedation, as an analgesic, and as a preanesthetic to local or general anesthesia.
Dosage
0.5 milligrams per pound intravenously or 1.0 milligram per pound intramuscularly.
Limitations
Not for use in horses intended for food.

Mule deer (Odocoileus hemionus), sika deer (Cervus nippon), and white-tailed deer (Odocoileus virginianus)

Indication
To produce sedation, as an analgesic, and as a preanesthetic to local anesthesia. To produce sedation, accompanied by a shorter period of analgesia. May be used to calm and facilitate handling of fractious animals for diagnostic procedures, for minor surgical procedures, for therapeutic medication for sedation and relief of pain following injury or surgery, and as a preanesthetic to local anesthetic. At the recommended dosages, can be used in conjunction with local anesthetics, such as procaine or lidocaine.
Dosage
Administer intramuscularly, by hand syringe, or by syringe dart, in the heavy muscles of the croup or shoulder 1 to 2 milligrams per pound.
Limitations
Do not use in domestic food-producing animals. Do not use in Cervidae less than 15 days before or during the hunting season.

Elk (Cervus canadensis)

Indication
To produce sedation, as an analgesic, and as a preanesthetic to local anesthesia. To produce sedation, accompanied by a shorter period of analgesia. May be used to calm and facilitate handling of fractious animals for diagnostic procedures, for minor surgical procedures, for therapeutic medication for sedation and relief of pain following injury or surgery, and as a preanesthetic to local anesthetic. At the recommended dosages, can be used in conjunction with local anesthetics, such as procaine or lidocaine.
Dosage
Administer intramuscularly, by hand syringe, or by syringe dart, in the heavy muscles of the croup or shoulder 0.25 to 0.5 milligrams per pound of body weight.
Limitations
Do not use in domestic food-producing animals. Do not use in Cervidae less than 15 days before or during the hunting season.

Cats

Indication
To produce sedation, as an analgesic, and as a preanesthetic to local or general anesthesia.
Dosage
0.5 milligrams per pound intravenously or 1.0 milligram per pound intramuscularly.

Fallow deer (Dama dama)

Indication
To produce sedation, as an analgesic, and as a preanesthetic to local anesthesia. To produce sedation, accompanied by a shorter period of analgesia. May be used to calm and facilitate handling of fractious animals for diagnostic procedures, for minor surgical procedures, for therapeutic medication for sedation and relief of pain following injury or surgery, and as a preanesthetic to local anesthetic. At the recommended dosages, can be used in conjunction with local anesthetics, such as procaine or lidocaine.
Dosage
Administer intramuscularly, by hand syringe, or by syringe dart, in the heavy muscles of the croup or shoulder 2 to 4 milligrams per pound.
Limitations
Do not use in domestic food-producing animals. Do not use in Cervidae less than 15 days before or during the hunting season.

XylaMed™

SPL · SPL

Open original
FDA Structured Product Label

XylaMed™

Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.

Sponsor
Bimeda Animal Health Ltd.
ANADA
200-529
Status
RX
Form
Injectable Solution
Species
Fallow Deer • Mule Deer • Sika Deer • White-Tailed Deer

<strong>Horses:</strong><br />

Dosage
Intravenously-0.5 mL/100 lbs body weight (0.5 mg/lb)
Intramuscularly-1.0 mL/100 lbs body weight (1.0 mg/lb)
Following injection of XYLAMED, the animal should be allowed to rest quietly until the full effect has been reached.
These dosages produce sedation which is usually maintained for 1 to 2 hours, and analgesia which lasts for 15 to 30 minutes.
2. Preanesthetic to Local Anesthesia:
XYLAMED at the recommended dosages can be used in conjunction with local anesthetics, such as procaine or lidocaine.
3. Preanesthetic to General Anesthesia:
XYLAMED at the recommended dosage rates, produces an additive effect to central nervous system depressants such as pentobarbital sodium, thiopental sodium and thiamylal sodium. Therefore, the dosage of such compounds should be reduced and administered to the desired effect. In general, only 1/3 to ½ of the calculated dosage of the barbiturates will be needed to produce a surgical plane of anesthesia. Post-anesthetic or emergence excitement has not been observed in animals preanesthetized with XYLAMED.
XylaMed™ has been used successfully as a preanesthetic agent for pentobarbital sodium, thiopental sodium, thiamylal sodium, nitrous oxide, ether, halothane, glyceryl guaiacolate, and methoxyflurane anesthesia.

<strong>Cervidae:</strong><br />

Indication
XYLAMED should be used in horses and Cervidae (Fallow Deer, Mule Deer, Sika Deer, White-Tailed Deer, and Elk) when it is desirable to produce a state of sedation accompanied by a shorter period of analgesia.
Horses: XYLAMED has been used successfully as follows:
1. Diagnostic procedures-oral and ophthalmic examinations, abdominal palpation, rectal palpation, vaginal examination, catheterization of the bladder and radiographic examinations.
2. Orthopedic procedures, such as application of casting materials and splints.
3. Dental procedures.
4. Minor surgical procedures of short duration such as debridement, removal of cutaneous neoplasms and suturing of lacerations.
5. To calm and facilitate handling of fractious animals.
6. Therapeutic medication for sedation and relief of pain following injury or surgery.
7. Major surgical procedures:
a. When used as a preanesthetic to general anesthesia.
b. When used in conjunction with local anesthetics.
Cervidae: XYLAMED may be used for the following:
1. To calm and facilitate handling of fractious animals.
2. Diagnostic procedures.
3. Minor surgical procedures.
4. Therapeutic medication for sedation and relief of pain following injury or surgery.
5. As a preanesthetic to local anesthesia.
XYLAMED at the recommended dosages can be used in conjunction with local anesthetics, such as procaine or lidocaine.
Dosage
Administer intramuscularly, by either hand syringe or syringe dart, in the heavy muscles of the croup or shoulder.
Dosage Range:
Fallow Deer (Dama dama)-2.0 to 4.0 mL/100 lbs body weight (2.0 to 4.0 mg/lb).
Mule Deer (Odocoileus hemionus)-1.0 to 2.0 mL/100 lbs body weight (1.0 to 2.0 mg/lb).
Sika Deer (Cervus nippon)-1.0 to 2.0 mL/100 lbs body weight (1.0 to 2.0 mg/lb).
White-Tailed Deer (Odocoileus virginianus)-1.0 to 2.0 mL/100 lbs body weight (1.0 to 2.0 mg/lb).
Elk (Cervus canadensis)-0.25 to 0.5 mL/100 lbs body weight (0.25 to 0.5 mg/lb).
Following injection of XYLAMED the animal should be allowed to rest quietly until the full effect has been reached.
These dosages produce sedation which is usually maintained for 1 to 2 hours and analgesia which lasts for 15 to 30 minutes

Chanazine®

SPL · SPL

Open original
FDA Structured Product Label

Chanazine®

Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.

Sponsor
Chanelle Pharmaceuticals Manufacturing Ltd.
ANADA
200-139
Status
RX
Form
Liquid (Solution)
Route
Intravenous, Intramuscular
Species
Horse • Fallow Deer • Elk • Mule Deer • Sika Deer • White-Tailed Deer
Composition / specifications
Each milliliter of solution contains xylazine hydrochloride equivalent to 100 milligrams xylazine or 300 milligrams xylazine.

Mule deer (Odocoileus hemionus), sika deer (Cervus nippon), and white-tailed deer (Odocoileus virginianus)

Indication
To produce sedation, as an analgesic, and as a preanesthetic to local anesthesia. To produce sedation, accompanied by a shorter period of analgesia. May be used to calm and facilitate handling of fractious animals for diagnostic procedures, for minor surgical procedures, for therapeutic medication for sedation and relief of pain following injury or surgery, and as a preanesthetic to local anesthetic. At the recommended dosages, can be used in conjunction with local anesthetics, such as procaine or lidocaine.
Dosage
Administer intramuscularly, by hand syringe, or by syringe dart, in the heavy muscles of the croup or shoulder 1 to 2 milligrams per pound.
Limitations
Do not use in domestic food-producing animals. Do not use in Cervidae less than 15 days before or during the hunting season.

Fallow deer (Dama dama)

Indication
To produce sedation, as an analgesic, and as a preanesthetic to local anesthesia. To produce sedation, accompanied by a shorter period of analgesia. May be used to calm and facilitate handling of fractious animals for diagnostic procedures, for minor surgical procedures, for therapeutic medication for sedation and relief of pain following injury or surgery, and as a preanesthetic to local anesthetic. At the recommended dosages, can be used in conjunction with local anesthetics, such as procaine or lidocaine.
Dosage
Administer intramuscularly, by hand syringe, or by syringe dart, in the heavy muscles of the croup or shoulder 2 to 4 milligrams per pound.
Limitations
Do not use in domestic food-producing animals. Do not use in Cervidae less than 15 days before or during the hunting season.

Elk (Cervus canadensis)

Indication
To produce sedation, as an analgesic, and as a preanesthetic to local anesthesia. To produce sedation, accompanied by a shorter period of analgesia. May be used to calm and facilitate handling of fractious animals for diagnostic procedures, for minor surgical procedures, for therapeutic medication for sedation and relief of pain following injury or surgery, and as a preanesthetic to local anesthetic. At the recommended dosages, can be used in conjunction with local anesthetics, such as procaine or lidocaine.
Dosage
Administer intramuscularly, by hand syringe, or by syringe dart, in the heavy muscles of the croup or shoulder 0.25 to 0.5 milligrams per pound of body weight.
Limitations
Do not use in domestic food-producing animals. Do not use in Cervidae less than 15 days before or during the hunting season.

Horses

Indication
To produce sedation, as an analgesic, and as a preanesthetic to local or general anesthesia.
Dosage
0.5 milligrams per pound intravenously or 1.0 milligram per pound intramuscularly.
Limitations
Not for use in horses intended for food.

Chanazine®

SPL · SPL

Open original
FDA Structured Product Label

Chanazine®

Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.

Sponsor
Chanelle Pharmaceuticals Manufacturing Ltd.
ANADA
200-184
Status
RX
Form
Liquid (Solution)
Route
Subcutaneous, Intramuscular, Intravenous
Species
Dog • Cat
Composition / specifications
Each milliliter of solution contains xylazine hydrochloride equivalent to 20 milligrams xylazine.

Dogs

Indication
To produce sedation, as an analgesic, and as a preanesthetic to local or general anesthesia.
Dosage
0.5 milligrams per pound intravenously or 1.0 milligram per pound intramuscularly.

Cats

Indication
To produce sedation, as an analgesic, and as a preanesthetic to local or general anesthesia.
Dosage
0.5 milligrams per pound intravenously or 1.0 milligram per pound intramuscularly.

Xylazine hydrochloride SPL

SPL · Structured Product Label

Open original
FDA Structured Product Label XML for Xylazine hydrochloride. Use the source link for the full official labeling record.

Xylazine Hydrochloride SPL

SPL · Structured Product Label

Open original
FDA Structured Product Label XML for Xylazine Hydrochloride. Use the source link for the full official labeling record.

Xylazine Hydrochloride SPL

SPL · Structured Product Label

Open original
FDA Structured Product Label XML for Xylazine Hydrochloride. Use the source link for the full official labeling record.

Xylazine SPL

SPL · Structured Product Label

Open original
FDA Structured Product Label XML for Xylazine. Use the source link for the full official labeling record.

Rompun SPL

SPL · Structured Product Label

Open original
FDA Structured Product Label XML for Rompun. Use the source link for the full official labeling record.

Xylazine SPL

SPL · Structured Product Label

Open original
FDA Structured Product Label XML for Xylazine. Use the source link for the full official labeling record.

Anased SPL

SPL · Structured Product Label

Open original
FDA Structured Product Label XML for Anased. Use the source link for the full official labeling record.

Xylazine Hydrochloride SPL

SPL · Structured Product Label

Open original
FDA Structured Product Label XML for Xylazine Hydrochloride. Use the source link for the full official labeling record.

Xylazine HCl SPL

SPL · Structured Product Label

Open original
FDA Structured Product Label XML for Xylazine HCl. Use the source link for the full official labeling record.

X SPL

SPL · Structured Product Label

Open original
FDA Structured Product Label XML for X. Use the source link for the full official labeling record.

Xylaxine SPL

SPL · Structured Product Label

Open original
FDA Structured Product Label XML for Xylaxine. Use the source link for the full official labeling record.

X SPL

SPL · Structured Product Label

Open original
FDA Structured Product Label XML for X. Use the source link for the full official labeling record.

Xylazine hydrochloride SPL

SPL · Structured Product Label

Open original
FDA Structured Product Label XML for Xylazine hydrochloride. Use the source link for the full official labeling record.

A200088_Org_2_24_1994.pdf

FOI · FOI

Open original

UCM539440.pdf

FOI · FOI

Open original

ucm069889.pdf

FOI · FOI

Open original

UCM508357.pdf

FOI · FOI

Open original

UCM508360.pdf

FOI · FOI

Open original

UCM474107.pdf

FOI · FOI

Open original

UCM396610.pdf

FOI · FOI

Open original

A200139_Orig_05_16_1995.pdf

FOI · FOI

Open original

A200184_Org_7_12_1996.pdf

FOI · FOI

Open original
Source metadata:
Veterinary reference (advanced)

Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.

At a Glance

Quick facts and links to official labeling and safety signals.

Data freshness
  • Reference facts: Source Roxee | Refreshed Aug 6, 2026, 7:47 PM UTC
    The reference fact projection used for browse cards and quick facts.
  • Animal Drugs @ FDA: Source FDA | Refreshed Aug 6, 2026, 7:47 PM UTC
    Applications/products are imported from FDA export data.
  • Animal Drugs @ FDA previews: Source FDA | Refreshed Feb 9, 2026, 3:05 AM UTC
    Label highlights/doc links are fetched from FDA preview endpoints.
  • Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed Aug 6, 2026, 7:47 PM UTC
    Package/product NDCs from FDA’s electronic listing directory (XLS).
  • openFDA reaction terms: Source FDA openFDA | Refreshed Aug 6, 2026, 7:52 PM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Aug 6, 2026, 7:52 PM UTC
Official (FDA)
Identity: Generic ingredient • FDA branded products available
Official FDA brands: Anased Rompun X Xylaxine Xylazine Xylazine HCl Xylazine Hydrochloride Xylazine hydrochloride
Manufacturer mapping: Multiple FDA labelers
Case-reported brands (openFDA): MSK
Catalog species: Both • FDA-labeled species: Cat, Dog, Elk, Fallow Deer, Horse, Mule Deer, Sika Deer, White-Tailed Deer
Rx/OTC: RX
Form/route: Injectable Solution, Liquid (Solution) • Intramuscular, Intravenous, Subcutaneous
Applications: NADA 47956 • NADA 47955 • ANADA 200-088 • NADA 140-442 • NADA 139-236 • ANADA 200-529 • ANADA 200-139 • ANADA 200-184
NDC: Packages 11695-4024-1 17033-099-05 58597-8582-6 58597-8582-8 62157-373-01 62157-374-01 • Products 11695 17033 58597 62157 62991 63537
Documents: 9 (FOI: 9) • SPL: 9 • Label highlights • Official documents
Safety (openFDA)
Top reactions: Dog 2 • Cat 9 • View
Case summaries: 8 (showing 8) • View
openFDA reports are unverified and do not prove causation.
Explore
Related conditions: Pain (acute, chronic)
Linked using: Fda_Label (0.95)
Diagnosis Codes

Diagnosis-code mappings are not available for this medication yet.

Counseling and Monitoring Highlights

Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.

Owner-facing counseling points
  • Federal law restricts this drug to use by or on the order of a licensed veterinarian. Do not use in horses intended for human consumption. Do not use in domestic food-producing animals. Do not use in Cervidae less than 15 days before or during the hunting season. (Contraindication, High)
Top reaction signals
Vomiting (1) Paraparesis (1) Panting (1) Otitis NOS (1) Myelopathy NOS (1) Medication error NOS (1) Malaise (1) Limb weakness (1)

Identifiers & Packages

Normalized identifiers (NDC/NADA/ANADA) and package metadata from regulator listings.

Identifiers
ANADA: 200088 ANADA: 200139 ANADA: 200184 ANADA: 200529 NADA: 139236 NADA: 140442 NADA: 47955 NADA: 47956 NDC Package: 11695-4024-1 NDC Package: 17033-099-05 NDC Package: 58597-8582-6 NDC Package: 58597-8582-8 NDC Package: 62157-373-01 NDC Package: 62157-374-01 NDC Package: 62991-1624-2 NDC Package: 62991-1624-3 NDC Package: 62991-1624-4 NDC Package: 63537-0091-5 NDC Package: 63537-0092-9 NDC Package: 64189-9001-0 NDC Package: 64189-9001-1 NDC Package: 64189-9001-2 NDC Package: 64189-9001-3 NDC Package: 64189-9002-0
Package NDC Product NDC Form / Route Status
11695-4024-1 11695 -
17033-099-05 17033 -
58597-8582-6 58597 -
58597-8582-8 58597 -
62157-373-01 62157 -
62157-374-01 62157 -
62991-1624-2 62991 -
62991-1624-3 62991 -
62991-1624-4 62991 -
63537-0091-5 63537 -
63537-0092-9 63537 -
64189-9001-0 64189 -
64189-9001-1 64189 -
64189-9001-2 64189 -
64189-9001-3 64189 -
64189-9002-0 64189 -
64189-9002-1 64189 -
64189-9002-2 64189 -
64189-9002-3 64189 -
69043-043-05 69043 -

Enriched Documents

Documents are tiered by source trust: Official, Clinical, Manufacturer, Marketing.

  • Xylazine hydrochloride SPL • Structured Product Label • Official
    FDA Structured Product Label from the electronic animal drug product listing directory.
  • Xylazine Hydrochloride SPL • Structured Product Label • Official
    FDA Structured Product Label from the electronic animal drug product listing directory.
  • Xylazine Hydrochloride SPL • Structured Product Label • Official
    FDA Structured Product Label from the electronic animal drug product listing directory.
  • Xylazine SPL • Structured Product Label • Official
    FDA Structured Product Label from the electronic animal drug product listing directory.
  • Rompun SPL • Structured Product Label • Official
    FDA Structured Product Label from the electronic animal drug product listing directory.
  • Xylazine SPL • Structured Product Label • Official
    FDA Structured Product Label from the electronic animal drug product listing directory.
  • Anased SPL • Structured Product Label • Official
    FDA Structured Product Label from the electronic animal drug product listing directory.
  • Xylazine Hydrochloride SPL • Structured Product Label • Official
    FDA Structured Product Label from the electronic animal drug product listing directory.
  • Xylazine HCl SPL • Structured Product Label • Official
    FDA Structured Product Label from the electronic animal drug product listing directory.
  • X SPL • Structured Product Label • Official
    FDA Structured Product Label from the electronic animal drug product listing directory.
  • Xylaxine SPL • Structured Product Label • Official
    FDA Structured Product Label from the electronic animal drug product listing directory.
  • X SPL • Structured Product Label • Official
    FDA Structured Product Label from the electronic animal drug product listing directory.
  • Xylazine hydrochloride SPL • Structured Product Label • Official
    FDA Structured Product Label from the electronic animal drug product listing directory.
  • A200088_Org_2_24_1994.pdf • FOI summary • Official • May 12, 2025
    FDA FOI summary for application 200088
  • UCM539440.pdf • FOI summary • Official • Feb. 26, 2025
    FDA FOI summary for application 140442
  • UCM474107.pdf • FOI summary • Official • June 13, 2024
    FDA FOI summary for application 139236
  • UCM508360.pdf • FOI summary • Official • June 13, 2024
    FDA FOI summary for application 139236
  • UCM508357.pdf • FOI summary • Official • June 13, 2024
    FDA FOI summary for application 139236
  • ucm069889.pdf • FOI summary • Official • June 13, 2024
    FDA FOI summary for application 139236
  • UCM396610.pdf • FOI summary • Official • Feb. 27, 2023
    FDA FOI summary for application 200529
  • A200139_Orig_05_16_1995.pdf • FOI summary • Official • July 28, 2017
    FDA FOI summary for application 200139
  • A200184_Org_7_12_1996.pdf • FOI summary • Official • May 22, 2017
    FDA FOI summary for application 200184

Data Sources & Change Log

Every non-trivial field is expected to include provenance and update timestamps.

Official 141 Clinical 1 Manufacturer 0 Marketing 0
Current Field Facts
  • side_effects: Top reported reactions (openFDA): Death, Lack of efficacy - NOS, Vomiting, Death by euthanasia, Hives (see also 'Skin'), INEFFECTIVE, ANESTHESIA. (Clinical, 2026-04-11)
  • contraindications: Federal law restricts this drug to use by or on the order of a licensed veterinarian. Do not use in horses intended for human consumption. Do not use in domest… (Official, 2026-04-12)
  • contraindications: Federal law restricts this drug to use by or on the order of a licensed veterinarian. Do not use in horses intended for human consumption. Do not use in domest… (Official, 2026-04-11)
  • contraindications: Federal law restricts this drug to use by or on the order of a licensed veterinarian. Do not use in horses intended for human consumption. Do not use in domest… (Official, 2026-02-12)
  • manufacturer_name: Multiple FDA labelers (Official, 2026-08-06)
  • manufacturer_name: Multiple FDA labelers (Official, 2026-08-05)
  • manufacturer_name: Multiple FDA labelers (Official, 2026-08-04)
  • manufacturer_name: Multiple FDA labelers (Official, 2026-08-03)
  • manufacturer_name: Multiple FDA labelers (Official, 2026-08-02)
  • manufacturer_name: Multiple FDA labelers (Official, 2026-08-01)
  • manufacturer_name: Multiple FDA labelers (Official, 2026-07-31)
  • manufacturer_name: Multiple FDA labelers (Official, 2026-07-30)
  • manufacturer_name: Multiple FDA labelers (Official, 2026-07-29)
  • manufacturer_name: Multiple FDA labelers (Official, 2026-07-28)
  • manufacturer_name: Multiple FDA labelers (Official, 2026-07-27)
  • manufacturer_name: Multiple FDA labelers (Official, 2026-07-26)
  • manufacturer_name: Multiple FDA labelers (Official, 2026-07-25)
  • manufacturer_name: Multiple FDA labelers (Official, 2026-07-25)
  • manufacturer_name: Multiple FDA labelers (Official, 2026-07-22)
  • manufacturer_name: Multiple FDA labelers (Official, 2026-07-22)
Recent Revisions
  • side_effects updated 2026-04-12 10:05 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-04-12 10:05 by etl_backfill • Backfilled from existing medication fields
  • usage updated 2026-04-12 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-04-11 10:05 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-04-11 10:05 by etl_backfill • Backfilled from existing medication fields
  • usage updated 2026-04-11 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields
  • usage updated 2026-02-12 22:44 by etl_backfill • Backfilled from existing medication fields

FDA Products & Applications (Animal Drugs @ FDA)

Official sponsor/proprietary-name/application-status records linked by active ingredient.

Product Sponsor Application Status Published
Rompun® Injectable (100 mg)
RX
Xylazine Hydrochloride
Liquid (Solution) • Intramuscular, Intravenous, Subcutaneous
Label highlights
Official documents
Dechra Veterinary Products LLC NADA 47956 Approved Jul 14, 2026
Rompun® Injectable (20 mg)
RX
Xylazine Hydrochloride
Liquid (Solution) • Intravenous, Intramuscular, Subcutaneous
Label highlights
Official documents
Dechra Veterinary Products LLC NADA 47955 W Jul 14, 2026
Sedazine™
RX
Xylazine Hydrochloride
Liquid (Solution) • Intramuscular, Intravenous
Label highlights
Official documents
Boehringer Ingelheim Animal Health USA Inc. ANADA 200-088 W May 12, 2025
Xylazine HCl Injection AnaSed® Equine Injection
RX
Xylazine Hydrochloride
Injectable Solution • Intramuscular, Intravenous
Label highlights
Official documents
Cronus Pharma Specialities India Private Ltd. NADA 140-442 Approved Feb 26, 2025
Anased®
RX
Xylazine Hydrochloride
Liquid (Solution) • Subcutaneous, Intramuscular, Intravenous
Label highlights
Official documents
Cronus Pharma Specialities India Private Ltd. NADA 139-236 Approved Jun 13, 2024
XylaMed™
RX
Xylazine
Injectable Solution
Label highlights
Official documents
Bimeda Animal Health Ltd. ANADA 200-529 Approved Feb 27, 2023
Chanazine®
RX
Xylazine Hydrochloride
Liquid (Solution) • Intravenous, Intramuscular
Label highlights
Official documents
Chanelle Pharmaceuticals Manufacturing Ltd. ANADA 200-139 Approved Jul 28, 2017
Chanazine®
RX
Xylazine Hydrochloride
Liquid (Solution) • Subcutaneous, Intramuscular, Intravenous
Label highlights
Official documents
Chanelle Pharmaceuticals Manufacturing Ltd. ANADA 200-184 Approved May 22, 2017

Data source: FDA Animal Drugs @ FDA (public search export).

What It's For (FDA Label Highlights)

Extracted from FDA Animal Drugs @ FDA product labeling. Always confirm details with your veterinarian.

Species: Horse • Fallow Deer • Elk • Mule Deer • Sika Deer • White-Tailed Deer
Composition / specifications
Each milliliter of solution contains xylazine hydrochloride equivalent to 100 milligrams xylazine
Horses
Indication
To produce sedation, as an analgesic, and as a preanesthetic to local or general anesthesia.
Dosage
0.5 milligrams per pound intravenously or 1.0 milligram per pound intramuscularly.
Limitations

Do not use in horses intended for human consumption.

Fallow deer (Dama dama)
Indication
To produce sedation, as an analgesic, and as a preanesthetic to local anesthesia. To produce sedation, accompanied by a shorter period of analgesia. May be used to calm and facilitate handling of fractious animals for diagnostic procedures, for minor surgical procedures, for therapeutic medication for sedation and relief of pain following injury or surgery, and as a preanesthetic to local anesthetic. At the recommended dosages, can be used in conjunction with local anesthetics, such as procaine or lidocaine.
Dosage
Administer intramuscularly, by hand syringe, or by syringe dart, in the heavy muscles of the croup or shoulder 2 to 4 milligrams per pound.
Limitations
Do not use in domestic food-producing animals. Do not use in Cervidae less than 15 days before or during the hunting season.
Mule deer (Odocoileus hemionus), sika deer (Cervus nippon), and white-tailed deer (Odocoileus virginianus)
Indication
To produce sedation, as an analgesic, and as a preanesthetic to local anesthesia. To produce sedation, accompanied by a shorter period of analgesia. May be used to calm and facilitate handling of fractious animals for diagnostic procedures, for minor surgical procedures, for therapeutic medication for sedation and relief of pain following injury or surgery, and as a preanesthetic to local anesthetic. At the recommended dosages, can be used in conjunction with local anesthetics, such as procaine or lidocaine.
Dosage
Administer intramuscularly, by hand syringe, or by syringe dart, in the heavy muscles of the croup or shoulder 1 to 2 milligrams per pound.
Limitations
Do not use in domestic food-producing animals. Do not use in Cervidae less than 15 days before or during the hunting season.
Elk (Cervus canadensis)
Indication
To produce sedation, as an analgesic, and as a preanesthetic to local anesthesia. To produce sedation, accompanied by a shorter period of analgesia. May be used to calm and facilitate handling of fractious animals for diagnostic procedures, for minor surgical procedures, for therapeutic medication for sedation and relief of pain following injury or surgery, and as a preanesthetic to local anesthetic. At the recommended dosages, can be used in conjunction with local anesthetics, such as procaine or lidocaine.
Dosage
Administer intramuscularly, by hand syringe, or by syringe dart, in the heavy muscles of the croup or shoulder 0.25 to 0.5 milligrams per pound of body weight.
Limitations
Do not use in domestic food-producing animals. Do not use in Cervidae less than 15 days before or during the hunting season.

FDA page: Open in Animal Drugs @ FDA

Species: Dog • Cat
Composition / specifications
Each milliliter of solution contains xylazine hydrochloride equivalent to 20 milligrams xylazine.
Cats
Indication
To produce sedation, as an analgesic, and as a preanesthetic to local or general anesthesia.
Dosage
0.5 milligrams per pound intravenously or 1.0 milligram per pound intramuscularly.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Dogs
Indication
To produce sedation, as an analgesic, and as a preanesthetic to local or general anesthesia.
Dosage
0.5 milligrams per pound intravenously or 1.0 milligram per pound intramuscularly.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian.

FDA page: Open in Animal Drugs @ FDA

Species: Horse • Fallow Deer • Elk • Mule Deer • Sika Deer • White-Tailed Deer
Composition / specifications
Each milliliter of solution contains xylazine hydrochloride equivalent to 100 milligrams xylazine or 300 milligrams xylazine.
Mule deer (Odocoileus hemionus), sika deer (Cervus nippon), and white-tailed deer (Odocoileus virginianus)
Indication
To produce sedation, as an analgesic, and as a preanesthetic to local anesthesia. To produce sedation, accompanied by a shorter period of analgesia. May be used to calm and facilitate handling of fractious animals for diagnostic procedures, for minor surgical procedures, for therapeutic medication for sedation and relief of pain following injury or surgery, and as a preanesthetic to local anesthetic. At the recommended dosages, can be used in conjunction with local anesthetics, such as procaine or lidocaine.
Dosage
Administer intramuscularly, by hand syringe, or by syringe dart, in the heavy muscles of the croup or shoulder 1 to 2 milligrams per pound.
Limitations
Do not use in domestic food-producing animals. Do not use in Cervidae less than 15 days before or during the hunting season.
Elk (Cervus canadensis)
Indication
To produce sedation, as an analgesic, and as a preanesthetic to local anesthesia. To produce sedation, accompanied by a shorter period of analgesia. May be used to calm and facilitate handling of fractious animals for diagnostic procedures, for minor surgical procedures, for therapeutic medication for sedation and relief of pain following injury or surgery, and as a preanesthetic to local anesthetic. At the recommended dosages, can be used in conjunction with local anesthetics, such as procaine or lidocaine.
Dosage
Administer intramuscularly, by hand syringe, or by syringe dart, in the heavy muscles of the croup or shoulder 0.25 to 0.5 milligrams per pound of body weight.
Limitations
Do not use in domestic food-producing animals. Do not use in Cervidae less than 15 days before or during the hunting season.
Fallow deer (Dama dama)
Indication
To produce sedation, as an analgesic, and as a preanesthetic to local anesthesia. To produce sedation, accompanied by a shorter period of analgesia. May be used to calm and facilitate handling of fractious animals for diagnostic procedures, for minor surgical procedures, for therapeutic medication for sedation and relief of pain following injury or surgery, and as a preanesthetic to local anesthetic. At the recommended dosages, can be used in conjunction with local anesthetics, such as procaine or lidocaine.
Dosage
Administer intramuscularly, by hand syringe, or by syringe dart, in the heavy muscles of the croup or shoulder 2 to 4 milligrams per pound.
Limitations
Do not use in domestic food-producing animals. Do not use in Cervidae less than 15 days before or during the hunting season.
Horses
Indication
To produce sedation, as an analgesic, and as a preanesthetic to local or general anesthesia
Dosage
0.5 milligrams per pound intravenously or 1.0 milligram per pound intramuscularly.
Limitations
Not for use in horses intended for food..

FDA page: Open in Animal Drugs @ FDA

Species: Horse
Composition / specifications
Each milliliter of solution contains xylazine hydrochloride equivalent to 100 milligrams of xylazine .
Horses
Indication
To produce sedation, as an analgesic, and as a preanesthetic to local or general anesthesia.
Dosage
0.5 milligrams per pound intravenously or 1.0 milligrams per pound intramuscularly.
Limitations

Do not use in horses intended for human consumption.

FDA page: Open in Animal Drugs @ FDA

Species: Dog • Horse • Cat • Fallow Deer • Elk • Mule Deer • Sika Deer • White-Tailed Deer
Composition / specifications
Each milliliter of solution contains xylazine hydrochloride equivalent to: 1) 20 milligrams xylazine, 2) 100 milligrams xylazine or 3) 300 milligrams xylazine.
Dogs
Indication
To produce sedation, as an analgesic, and as a preanesthetic to local or general anesthesia.
Dosage
0.5 milligrams per pound intravenously or 1.0 milligram per pound intramuscularly.
Limitations
Horses
Indication
To produce sedation, as an analgesic, and as a preanesthetic to local or general anesthesia.
Dosage
0.5 milligrams per pound intravenously or 1.0 milligram per pound intramuscularly.
Limitations
Not for use in horses intended for food.
Mule deer (Odocoileus hemionus), sika deer (Cervus nippon), and white-tailed deer (Odocoileus virginianus)
Indication
To produce sedation, as an analgesic, and as a preanesthetic to local anesthesia. To produce sedation, accompanied by a shorter period of analgesia. May be used to calm and facilitate handling of fractious animals for diagnostic procedures, for minor surgical procedures, for therapeutic medication for sedation and relief of pain following injury or surgery, and as a preanesthetic to local anesthetic. At the recommended dosages, can be used in conjunction with local anesthetics, such as procaine or lidocaine.
Dosage
Administer intramuscularly, by hand syringe, or by syringe dart, in the heavy muscles of the croup or shoulder 1 to 2 milligrams per pound.
Limitations
Do not use in domestic food-producing animals. Do not use in Cervidae less than 15 days before or during the hunting season.
Elk (Cervus canadensis)
Indication
To produce sedation, as an analgesic, and as a preanesthetic to local anesthesia. To produce sedation, accompanied by a shorter period of analgesia. May be used to calm and facilitate handling of fractious animals for diagnostic procedures, for minor surgical procedures, for therapeutic medication for sedation and relief of pain following injury or surgery, and as a preanesthetic to local anesthetic. At the recommended dosages, can be used in conjunction with local anesthetics, such as procaine or lidocaine.
Dosage
Administer intramuscularly, by hand syringe, or by syringe dart, in the heavy muscles of the croup or shoulder 0.25 to 0.5 milligrams per pound of body weight.
Limitations
Do not use in domestic food-producing animals. Do not use in Cervidae less than 15 days before or during the hunting season.
Cats
Indication
To produce sedation, as an analgesic, and as a preanesthetic to local or general anesthesia.
Dosage
0.5 milligrams per pound intravenously or 1.0 milligram per pound intramuscularly.
Limitations
Fallow deer (Dama dama)
Indication
To produce sedation, as an analgesic, and as a preanesthetic to local anesthesia. To produce sedation, accompanied by a shorter period of analgesia. May be used to calm and facilitate handling of fractious animals for diagnostic procedures, for minor surgical procedures, for therapeutic medication for sedation and relief of pain following injury or surgery, and as a preanesthetic to local anesthetic. At the recommended dosages, can be used in conjunction with local anesthetics, such as procaine or lidocaine.
Dosage
Administer intramuscularly, by hand syringe, or by syringe dart, in the heavy muscles of the croup or shoulder 2 to 4 milligrams per pound.
Limitations
Do not use in domestic food-producing animals. Do not use in Cervidae less than 15 days before or during the hunting season.

FDA page: Open in Animal Drugs @ FDA

Species: Fallow Deer • Mule Deer • Sika Deer • White-Tailed Deer
<strong>Horses:</strong><br />
Indication
Dosage
Intravenously-0.5 mL/100 lbs body weight (0.5 mg/lb)
Intramuscularly-1.0 mL/100 lbs body weight (1.0 mg/lb)
Following injection of XYLAMED, the animal should be allowed to rest quietly until the full effect has been reached.
These dosages produce sedation which is usually maintained for 1 to 2 hours, and analgesia which lasts for 15 to 30 minutes.
2. Preanesthetic to Local Anesthesia:
XYLAMED at the recommended dosages can be used in conjunction with local anesthetics, such as procaine or lidocaine.
3. Preanesthetic to General Anesthesia:
XYLAMED at the recommended dosage rates, produces an additive effect to central nervous system depressants such as pentobarbital sodium, thiopental sodium and thiamylal sodium. Therefore, the dosage of such compounds should be reduced and administered to the desired effect. In general, only 1/3 to ½ of the calculated dosage of the barbiturates will be needed to produce a surgical plane of anesthesia. Post-anesthetic or emergence excitement has not been observed in animals preanesthetized with XYLAMED.
XylaMed™ has been used successfully as a preanesthetic agent for pentobarbital sodium, thiopental sodium, thiamylal sodium, nitrous oxide, ether, halothane, glyceryl guaiacolate, and methoxyflurane anesthesia.
Limitations
<strong>Cervidae:</strong><br />
Indication
XYLAMED should be used in horses and Cervidae (Fallow Deer, Mule Deer, Sika Deer, White-Tailed Deer, and Elk) when it is desirable to produce a state of sedation accompanied by a shorter period of analgesia.
Horses: XYLAMED has been used successfully as follows:
1. Diagnostic procedures-oral and ophthalmic examinations, abdominal palpation, rectal palpation, vaginal examination, catheterization of the bladder and radiographic examinations.
2. Orthopedic procedures, such as application of casting materials and splints.
3. Dental procedures.
4. Minor surgical procedures of short duration such as debridement, removal of cutaneous neoplasms and suturing of lacerations.
5. To calm and facilitate handling of fractious animals.
6. Therapeutic medication for sedation and relief of pain following injury or surgery.
7. Major surgical procedures:
a. When used as a preanesthetic to general anesthesia.
b. When used in conjunction with local anesthetics.
Cervidae: XYLAMED may be used for the following:
1. To calm and facilitate handling of fractious animals.
2. Diagnostic procedures.
3. Minor surgical procedures.
4. Therapeutic medication for sedation and relief of pain following injury or surgery.
5. As a preanesthetic to local anesthesia.
XYLAMED at the recommended dosages can be used in conjunction with local anesthetics, such as procaine or lidocaine.
Dosage
Administer intramuscularly, by either hand syringe or syringe dart, in the heavy muscles of the croup or shoulder.
Dosage Range:
Fallow Deer (Dama dama)-2.0 to 4.0 mL/100 lbs body weight (2.0 to 4.0 mg/lb).
Mule Deer (Odocoileus hemionus)-1.0 to 2.0 mL/100 lbs body weight (1.0 to 2.0 mg/lb).
Sika Deer (Cervus nippon)-1.0 to 2.0 mL/100 lbs body weight (1.0 to 2.0 mg/lb).
White-Tailed Deer (Odocoileus virginianus)-1.0 to 2.0 mL/100 lbs body weight (1.0 to 2.0 mg/lb).
Elk (Cervus canadensis)-0.25 to 0.5 mL/100 lbs body weight (0.25 to 0.5 mg/lb).
Following injection of XYLAMED the animal should be allowed to rest quietly until the full effect has been reached.
These dosages produce sedation which is usually maintained for 1 to 2 hours and analgesia which lasts for 15 to 30 minutes
Limitations

FDA page: Open in Animal Drugs @ FDA

Species: Horse • Fallow Deer • Elk • Mule Deer • Sika Deer • White-Tailed Deer
Composition / specifications
Each milliliter of solution contains xylazine hydrochloride equivalent to 100 milligrams xylazine or 300 milligrams xylazine.
Mule deer (Odocoileus hemionus), sika deer (Cervus nippon), and white-tailed deer (Odocoileus virginianus)
Indication
To produce sedation, as an analgesic, and as a preanesthetic to local anesthesia. To produce sedation, accompanied by a shorter period of analgesia. May be used to calm and facilitate handling of fractious animals for diagnostic procedures, for minor surgical procedures, for therapeutic medication for sedation and relief of pain following injury or surgery, and as a preanesthetic to local anesthetic. At the recommended dosages, can be used in conjunction with local anesthetics, such as procaine or lidocaine.
Dosage
Administer intramuscularly, by hand syringe, or by syringe dart, in the heavy muscles of the croup or shoulder 1 to 2 milligrams per pound.
Limitations
Do not use in domestic food-producing animals. Do not use in Cervidae less than 15 days before or during the hunting season.
Fallow deer (Dama dama)
Indication
To produce sedation, as an analgesic, and as a preanesthetic to local anesthesia. To produce sedation, accompanied by a shorter period of analgesia. May be used to calm and facilitate handling of fractious animals for diagnostic procedures, for minor surgical procedures, for therapeutic medication for sedation and relief of pain following injury or surgery, and as a preanesthetic to local anesthetic. At the recommended dosages, can be used in conjunction with local anesthetics, such as procaine or lidocaine.
Dosage
Administer intramuscularly, by hand syringe, or by syringe dart, in the heavy muscles of the croup or shoulder 2 to 4 milligrams per pound.
Limitations
Do not use in domestic food-producing animals. Do not use in Cervidae less than 15 days before or during the hunting season.
Elk (Cervus canadensis)
Indication
To produce sedation, as an analgesic, and as a preanesthetic to local anesthesia. To produce sedation, accompanied by a shorter period of analgesia. May be used to calm and facilitate handling of fractious animals for diagnostic procedures, for minor surgical procedures, for therapeutic medication for sedation and relief of pain following injury or surgery, and as a preanesthetic to local anesthetic. At the recommended dosages, can be used in conjunction with local anesthetics, such as procaine or lidocaine.
Dosage
Administer intramuscularly, by hand syringe, or by syringe dart, in the heavy muscles of the croup or shoulder 0.25 to 0.5 milligrams per pound of body weight.
Limitations
Do not use in domestic food-producing animals. Do not use in Cervidae less than 15 days before or during the hunting season.
Horses
Indication
To produce sedation, as an analgesic, and as a preanesthetic to local or general anesthesia.
Dosage
0.5 milligrams per pound intravenously or 1.0 milligram per pound intramuscularly.
Limitations
Not for use in horses intended for food.

FDA page: Open in Animal Drugs @ FDA

Species: Dog • Cat
Composition / specifications
Each milliliter of solution contains xylazine hydrochloride equivalent to 20 milligrams xylazine.
Dogs
Indication
To produce sedation, as an analgesic, and as a preanesthetic to local or general anesthesia.
Dosage
0.5 milligrams per pound intravenously or 1.0 milligram per pound intramuscularly.
Limitations
Cats
Indication
To produce sedation, as an analgesic, and as a preanesthetic to local or general anesthesia.
Dosage
0.5 milligrams per pound intravenously or 1.0 milligram per pound intramuscularly.
Limitations

FDA page: Open in Animal Drugs @ FDA

Usage

To produce sedation, as an analgesic, and as a preanesthetic to local or general anesthesia. To produce sedation, as an analgesic, and as a preanesthetic to local anesthesia. To produce sedation, accompanied by a shorter period of analgesia. May be used to calm and facilitate handling of fractious animals for diagnostic procedures, for minor surgical procedures, for therapeutic medication for sedation and relief of pain following injury or surgery, and as a preanesthetic to local anesthetic. At the recommended dosages, can be used in conjunction with local anesthetics, such as procaine or lidocaine. To produce sedation, as an analgesic, and as a preanesthetic to local or general anesthesia

Source: FDA Animal Drugs @ FDA • Reference

Contraindications

Federal law restricts this drug to use by or on the order of a licensed veterinarian. Do not use in horses intended for human consumption. Do not use in domestic food-producing animals. Do not use in Cervidae less than 15 days before or during the hunting season.

Top Reported Reactions (openFDA)

De-duplicated reaction terms grouped by body system from FDA openFDA reports (not verified; does not prove causation).

Digestive
Vomiting (1) • Dog Nausea (1) • Cat Drooling (1) • Cat

Showing top 5 for Digestive.

Effectiveness
Lack of efficacy - NOS (1) • Cat

Showing top 5 for Effectiveness.

Other
Paraparesis (1) • Dog Panting (1) • Dog Otitis NOS (1) • Cat Myelopathy NOS (1) • Dog Medication error NOS (1) • Cat
Show more (23)
Malaise (1) • Dog Locomotor disturbance (1) • Cat Limb weakness (1) • Dog Knuckling (1) • Dog Intentional misuse (1) • Cat Hyperthermia (1) • Dog Hyperaemic mucosae (1) • Dog Hyperactivity (1) • Cat Hind limb paralysis (1) • Cat Hallucination (1) • Cat Gastric ulcer (1) • Dog Fluid in abdomen NOS (1) • Dog Falling (1) • Cat Excitation (1) • Dog Elevated renal parameters (1) • Dog Difficulty standing (1) • Dog Death by euthanasia (1) • Cat Death (1) • Cat Cyanosis (1) • Cat Arched back (1) • Dog Abnormal ultrasound finding (1) • Dog Abnormal radiograph finding (1) • Cat Abdominal pain (1) • Dog

Showing top 5 for Other.

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Adverse Event Case Summaries (openFDA)

These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.

Cat, Cat (unknown), Unknown • Drug: MSK, Unknown • Reactions: Nausea, Drooling • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2026-US-009864
  • Serious AE: No
  • Treated For AE: No
  • Sex: Unknown
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Nausea Drooling
Outcomes: Recovered/Normal

Cat, Domestic Shorthair, Male, 6 month, 4.33 kilogram • Drug: MSK, Unknown • Reactions: Hallucination, Hyperactivity, Falling, Locomotor disturbance • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2026-US-004923
  • Serious AE: No
  • Treated For AE: No
  • Sex: Male
  • Age: 6.00 Month
  • Weight: 4.330 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Hallucination Hyperactivity Falling Locomotor disturbance
Outcomes: Ongoing

Dog, Greyhound, Female, 9 year, 27.3 kilogram • Drug: MSK, Solution, Subcutaneous • Reactions: Lack of efficacy - NOS, Unrelated death • Outcome: Euthanized

  • Report ID: USA-USFDACVM-2025-US-075461
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 9.00 Year
  • Weight: 27.300 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Subcutaneous
  • Form: Solution
Reactions Reported:
Lack of efficacy - NOS Unrelated death
Outcomes: Euthanized

Dog, ['Retriever - Golden', 'Poodle - Standard'], Male, 5 year, 25.5 kilogram • Drug: MSK, Solution, Subcutaneous • Reactions: Lack of efficacy - NOS, Unrelated death • Outcome: Euthanized

  • Report ID: USA-USFDACVM-2025-US-075440
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 5.00 Year
  • Weight: 25.500 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Subcutaneous
  • Form: Solution
Reactions Reported:
Lack of efficacy - NOS Unrelated death
Outcomes: Euthanized

Dog, Crossbred Canine/dog, Male, 14 year, 17.7 kilogram • Drug: MSK, Solution, Subcutaneous • Reactions: Lack of efficacy - NOS, Unrelated death • Outcome: Euthanized

  • Report ID: USA-USFDACVM-2025-US-075367
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 14.00 Year
  • Weight: 17.700 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Subcutaneous
  • Form: Solution
Reactions Reported:
Lack of efficacy - NOS Unrelated death
Outcomes: Euthanized

Dog, Dog (unknown), Unknown • Drug: MSK, Injection, Intramuscular, Dose: 1 dose per animal, Frequency: 1 per day • Reactions: Lack of efficacy - NOS • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2025-US-071331
  • Serious AE: No
  • Treated For AE: Yes
  • Sex: Unknown
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Intramuscular
  • Form: Injection
  • Dose: 1 dose per animal
  • Frequency: 1 per day
Reactions Reported:
Lack of efficacy - NOS
Outcomes: Recovered/Normal

Cat, Cat (unknown), Unknown • Drug: MSK, Injection, Intramuscular, Dose: 1 dose per animal, Frequency: 1 per day • Reactions: Lack of efficacy - NOS • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2025-US-071320
  • Serious AE: No
  • Treated For AE: Yes
  • Sex: Unknown
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Intramuscular
  • Form: Injection
  • Dose: 1 dose per animal
  • Frequency: 1 per day
Reactions Reported:
Lack of efficacy - NOS
Outcomes: Recovered/Normal

Cat, Domestic Shorthair, Male, 2 year, 4.536 kilogram • Drug: MSK, Injection, solution, Unknown • Reactions: Seizure NOS, Death by euthanasia • Outcome: Euthanized

  • Report ID: USA-USFDACVM-2025-US-072459
  • Serious AE: Yes
  • Treated For AE: No
  • Sex: Male
  • Age: 2.00 Year
  • Weight: 4.536 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Injection, solution
Reactions Reported:
Seizure NOS Death by euthanasia
Outcomes: Euthanized

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Overdose Information

No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.

Storage & Handling

No approved storage guidance is linked yet for this ingredient. Use manufacturer packaging and veterinary guidance for handling/storage.

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