Medication reference facts with explicit FDA-approval, off-label, source-limited, and safety context. Roxee does not sell, prescribe, or dispense medications.
DogReference completeFDA data linkedRx requiredInjectionMultiple FDA labelers
Official label facts
Owner quick guide first
Start here first for the safest next-step summary before the deeper medication detail.
Used for:
For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries
Dosing note:
Exact dosing depends on your pet's species, weight, and health status. Use your veterinarian's instructions for the exact dose and schedule.
What to watch for:
Avoid combining with other NSAIDs or corticosteroids
Use caution with kidney/liver disease or GI ulcer history
wobbly/unsteady walking (1 reports)
Loss of appetite (1 reports)
When to call the vet:
Repeated vomiting or diarrhea.
Severe lethargy (hard to wake, very low energy).
Collapse or fainting.
Trouble breathing.
Facial swelling or hives.
Blood in vomit or stool.
Bloodwork changes are grouped in Vet View.
What to tell or ask your vet today:
Is this medicine the right fit for my pet’s current symptoms?
Which warning signs mean I should call back right away?
How should I handle missed doses or refusal to take the medicine?
A source-aware map of what to know, what is uncertain, and what to verify with your veterinarian.
Source Backed Signals
What to know
Evidence-backed contextLimited
Roxee has limited cited overview evidence for Carprofen; use the official documents and your veterinarian's instructions for product-specific decisions.
Source: openFDA case USA-USFDACVM-2025-US-075245
Safety signal coverageReported signals
32 tracked reaction signals; 32 reported cases; 31 serious reports; 2 species groups. These are reporting and label-derived signals for interpretation with a veterinarian.
Source: openFDA case USA-USFDACVM-2025-US-075245
Interpretation guardrailNot causation
Adverse-event reports help form a watch list, but they do not prove the medication caused the reaction and they are not a risk ranking between medications.
Evidence tension
Stronger signalLabel / review
Official labels, package inserts, and reviewed summaries carry more weight than isolated reports.
Source: openFDA case USA-USFDACVM-2025-US-075245
Weaker signalReported data
Case reports and openFDA terms are useful for pattern awareness, but they are incomplete, can include multiple exposures, and do not estimate an individual pet's probability of harm.
Reaction signal map
Most reported reactionsTop terms
Unsteady walking (ataxia) (1 reports), Loss of appetite (1 reports), Decreased blood urea nitrogen (BUN) or creatinine (1 reports), Decreased appetite (1 reports), Death by euthanasia (1 reports)
Terrier - Bull - American Pit (1), Siberian Husky (1), Domestic Shorthair (1), Weimaraner (1). These are report metadata, not proof that a breed is at higher risk.
What your vet may verify
Fit for this patientVet check
Verify whether Carprofen fits the pet's species, current diagnosis, age, weight, organ status, pregnancy/lactation status, and concurrent medications.
Evidence limitationsEvidence review
Separate label-backed warnings from adverse-event reports and owner observations before changing the plan.
What to watch next
Watch listOwner-safe
Avoid combining with other NSAIDs or corticosteroids, Use caution with kidney/liver disease or GI ulcer history, wobbly/unsteady walking, Loss of appetite
Call sooner ifEscalation
Repeated vomiting or diarrhea. Severe lethargy (hard to wake, very low energy). Collapse or fainting.
Bottom line: Use this Carprofen brief as a structured watch list and source map, not as a reason to start, stop, or change treatment without your veterinarian.
Source-backed clinical checkpoints for quick review.
FDA-labeled species
Dog
Indication / use
For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries
WeaknessNot eatingLying downInappropriate urinationDifficulty standingWalking slowlyCollapse NOS (see also Cardio-vascular and Neurological disorders)Pain NOSSneezingCough, productiveInvoluntary urinationUnable to walkLeucocytosis NOSAnaemia NOSDecreased blood urea nitrogen (BUN) or creatinineAbdominal painGastric ulcerSeizure NOSDeathLack of efficacy - NOS
Body systems
OtherNeurologicEffectiveness
Outcomes
Died
USA-USFDACVM-2025-US-072814
Received 2025-12-10
· MSK
· MSK
Serious
Species
Dog
Breed
Pinscher - Miniature
Size / weight
Under 10 lb (4.037 Kilogram)
Age
8+ years (1 Year)
Sex
Female Unknown
Region
USA
Reactions
Lethargy (see also Central nervous system depression in Neurological)TremblingLimpingHead downWalking difficultyFeverLack of efficacy - NOSElevated globulinsBlood in urineImmune-mediated polyarthropathyElevated protein:creatinine ratioProteinuriaIntentional misuse
Body systems
NeurologicOtherEffectiveness
Outcomes
Ongoing
Tap or hover a reaction to see what it means in plain language.
Tracked signals
32
Reported cases
32
Serious reports
31
Species represented
2
Grouped by Body System
Digestive (3)
· Loss of appetite, Decreased appetite, Bloody diarrhoea
Neurologic (2)
· Unsteady walking (ataxia), Circling - neurological disorder
Other (27)
· Decreased blood urea nitrogen (BUN) or creatinine, Death by euthanasia, Death
Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.
Sponsor
Dechra Veterinary Products LLC
ANADA
200-575
Status
RX
Form
Scored Chewable Tablets
Route
Oral
Species
Dog
Composition / specifications
25 mg, 75 mg, and 100 mg tablets
Label highlights
Indication
For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries
Dosage
The recommended dosage for oral administration to dogs is 2 mg/lb (4.4 mg/kg) of body weight daily. The total daily dose may be administered as 2 mg/lb of body weight daily or divided and administered as 1 mg/lb (2.2 mg/kg) twice daily. For the control of postoperative pain, administer approximately 2 hours before the procedure. Tablets are scored and dosage should be calculated in half-tablet increments
Limitations
Federal Law restricts this drug to use by or on the order of a licensed veterinarian
Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.
Sponsor
Dechra Veterinary Products LLC
ANADA
200-366
Status
RX
Form
Caplet
Route
Oral
Species
Dog
Composition / specifications
Each caplet contains 25, 75, or 100 milligrams (mg) carprofen.
Dogs
Indication
For the relief of pain and inflammation
associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries.
Dosage
2 milligram per pound of body weight once daily or 1 milligram per pound twice daily.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.
Sponsor
Dechra Veterinary Products LLC
ANADA
200-366
Status
RX
Form
Caplet
Route
Oral
Species
Dog
Composition / specifications
Each caplet contains 25, 75, or 100 milligrams (mg) carprofen.
Dogs
Indication
For the relief of pain and inflammation
associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries.
Dosage
2 milligram per pound of body weight once daily or 1 milligram per pound twice daily.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.
Sponsor
Felix Pharmaceuticals Pvt. Ltd.
ANADA
200-767
Status
RX
Form
Flavored Tablets
Route
Oral
Species
Dog
Composition / specifications
25 mg, 75 mg, or 100 mg of carprofen per tablet
Dogs
Indication
For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs.
Dosage
2 milligram per pound (4.4 mg/kg) of body weight once daily or 1 milligram per pound twice daily.
Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.
Sponsor
Ajenat Pharmaceuticals LLC
ANADA
200-578
Status
RX
Form
Tablet
Route
Oral
Species
Dog
Label highlights
Indication
For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs
Dosage
The recommended dosage for oral administration to dogs is 2 mg/lb (4.4 mg/kg) of body weight daily. The total daily dose may be administered as 2 mg/lb of body weight once daily or divided and administered as 1 mg/lb (2.2. mg/kg) twice daily. For the control of postoperative pain, administer approximately 2 hours before the procedure. Tablets are scored and dosage should be calculated in half-tablet increments
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian
Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.
Sponsor
Ajenat Pharmaceuticals LLC
ANADA
200-397
Status
RX
Form
Caplet
Route
Oral
Species
Dog
Composition / specifications
Each caplet or chewable tablet contains 25, 75, or 100 milligrams (mg) carprofen.
Dogs
Indication
For the control of postoperative pain associated with soft tissue and orthopedic surgery. For the relief of pain and inflammation associated with osteoarthritis
Dosage
2 milligram per pound of body weight once daily or 1 milligram per pound twice daily.
Limitations
For the control of postoperative pain, administer approximately 2 hours before the procedure. Federal law restricts this drug to use by or on the order of a licensed veterinarian
Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.
Sponsor
Cronus Pharma Specialities India Private Ltd.
ANADA
200-762
Status
RX
Form
Injectable Solution
Route
Subcutaneous
Species
Dog
Composition / specifications
50 mg/mL
Dogs
Indication
For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs.
Dosage
The recommended dosage for subcutaneous administration to dogs is 2 mg/lb (4.4 mg/kg) of body weight daily. The total daily dose may be administered as either 2 mg/lb of body weight once daily or divided and administered as 1 mg/lb (2.2 mg/kg) twice daily. For control of postoperative pain, administer approximately 2 hours before the procedure.
Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.
Sponsor
Cronus Pharma Specialities India Private Ltd.
ANADA
200-687
Status
RX
Form
Chewable Tablets
Route
Oral
Species
Dog
Composition / specifications
25 mg, 37.5 mg, 50 mg, 75 mg, and 100 mg of carprofen per tablet
Dogs
Indication
For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs.
Dosage
The recommended dosage for oral administration to dogs is 2 mg/lb (4.4 mg/kg) of body weight daily. The total daily dose may be administered as 2 mg/lb of body weight once daily or divided and administered as 1 mg/lb (2.2 mg/kg) twice daily. For the control of postoperative pain, administer approximately 2 hours before the procedure. For scored tablets, dosage should be calculated in half-tablet increments.
Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.
Sponsor
Felix Pharmaceuticals Pvt. Ltd.
ANADA
200-777
Status
RX
Form
Injectable Solution
Route
Subcutaneous
Species
Dog
Composition / specifications
50 mg/mL
Dogs
Indication
For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs.
Dosage
The recommended dosage for subcutaneous administration to dogs is 2 mg/lb (4.4 mg/kg) of body weight daily. The total daily dose may be administered as either 2 mg/lb of body weight once daily or divided and administered as 1 mg/lb (2.2 mg/kg) twice daily. For control of postoperative pain, administer approximately 2 hours before procedure.
Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.
Sponsor
Felix Pharmaceuticals Pvt. Ltd.
ANADA
200-706
Status
RX
Form
Chewable Tablets
Route
Oral
Species
Dog
Composition / specifications
25 mg, 75 mg, and 100 mg of carprofen per tablet
Dogs
Indication
For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs.
Dosage
The recommended dosage for oral administration to dogs is 2 mg/lb (4.4 mg/kg) of body weight daily. The total daily dose may be administered as 2 mg/lb of body weight once daily or divided and administered as 1 mg/lb (2.2 mg/kg) twice daily. For the control of postoperative pain, administer approximately 2 hours before the procedure. For scored tablets, dosage should be calculated in half-tablet increments.
Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.
Sponsor
Felix Pharmaceuticals Pvt. Ltd.
ANADA
200-795
Status
RX
Form
Chewable Tablets
Route
Oral
Composition / specifications
25 mg, 75 mg, or 100 mg of carprofen per tablet
Dogs
Indication
For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs.
Dosage
The recommended dosage for oral administration to dogs is 2 mg/lb of body weight daily. The total daily dose may be administered as 2 mg/lb of body weight once daily or divided and administered as 1 mg/lb twice daily. For the control of postoperative pain, administer approximately 2 hours before the procedure.
Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.
Sponsor
ZYVET AH, Inc.
ANADA
200-739
Status
RX
Form
Chewable Tablets
Route
Oral
Species
Dog
Composition / specifications
25 mg, 75 mg and 100 mg of carprofen per tablet
Dogs
Indication
For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs.
Dosage
The recommended dosage for oral administration to dogs is 2 mg/lb of body weight daily. The total daily dose may be administered as 2 mg/lb of body weight once daily or divided and administered as 1 mg/lb twice daily. For the control of postoperative pain, administer approximately 2 hours before the procedure. Carprofen chewable tablets are scored and dosage should be calculated in half-tablet increments.
Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.
Sponsor
Norbrook Laboratories, Ltd.
ANADA
200-498
Status
RX
Form
Tablet
Route
Oral
Species
Dog
Composition / specifications
Each caplet or chewable tablet contains 25, 75, or 100 milligrams (mg) carprofen.
Dogs
Indication
Carprofen is indicated for the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries In dogs.
Dosage
2 milligram per pound of body weight once daily or 1 milligram per pound twice daily.
Limitations
For use in dogs only. Do not use in cats.
Carprofen should not be used in dogs exhibiting previous hypersensitivity to carprofen.
Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.
Sponsor
Felix Pharmaceuticals Pvt. Ltd.
ANADA
200-732
Status
RX
Form
Caplet
Route
Oral
Species
Dog
Composition / specifications
25 mg, 75 mg, or 100 mg of carprofen per caplet
Dogs
Indication
For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs.
Dosage
The recommended dosage for oral administration to dogs is 2 mg/lb (4.4 mg/kg) of body weight daily. The total daily dose may be administered as 2 mg/lb of body weight once daily or divided and administered as 1 mg/lb (2.2 mg/kg) twice daily. For the control of postoperative pain, administer approximately 2 hours before the procedure.
Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.
Sponsor
Norbrook Laboratories, Ltd.
ANADA
200-520
Status
RX
Form
Injectable Solution
Route
Subcutaneous
Species
Dog
Composition / specifications
Each milliliter (mL) contains 50 milligrams (mg) of carprofen.
Label highlights
Indication
For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs.
Dosage
The recommended dosage for subcutaneous administration to dogs is 2 mg/lb (4.4 mg/kg) of body weight daily. The total daily dose may be administered as either 2 mg/lb of body weight once daily or divided and administered as 1 mg/lb (2.2 mg/kg) twice daily. For control of postoperative pain, administer approximately 2 hours before the procedure.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.
Sponsor
Zoetis Inc.
NADA
141-199
Status
RX
Form
Liquid (Solution)
Route
Subcutaneous
Species
Dog
Composition / specifications
Each milliliter of solution contains 50 milligrams carprofen.
Dogs
Indication
For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries.
Dosage
2 milligram per pound (4.4 milligrams per kilogram) body weight once daily or 1 milligram per pound (2.2 milligrams per kilogram) body weight twice daily, by subcutaneous injection.
Limitations
For use in dogs only. Do not use in cats.
Federal law restricts this drug to use by or on the order of a licensed veterinarian.
For the control of postoperative pain, administer approximately 2 hours before the procedure.
Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.
Sponsor
Dechra Veterinary Products LLC
ANADA
200-703
Status
RX
Form
Caplet
Route
Oral
Species
Dog
Composition / specifications
25, 75, or 100 mg carprofen per caplet
Dogs
Indication
For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs.
Dosage
The recommended dosage for oral administration to dogs is 2 mg/lb (4.4 mg/kg) of body weight daily. The total daily dose may be administered as 2 mg/lb of body weight daily or divided and administered as 1 mg/lb (2.2 mg/kg) twice daily. For the control of postoperative pain, administer approximately 2 hours before the procedure.
Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.
Sponsor
Dechra Veterinary Products LLC
ANADA
200-681
Status
RX
Form
Flavored Tablets
Route
Oral
Species
Dog
Composition / specifications
25 mg, 75 mg, or 100 mg of carprofen per tablet
Dogs
Indication
For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs.
Dosage
The recommended dosage for oral administration to dogs is 2 mg/lb (4.4 mg/kg) of body weight daily. The total daily dose may be administered as 2 mg/lb of body weight once daily or divided and administered as 1 mg/lb (2.2 mg/kg) twice daily. For the control of postoperative pain, administer approximately 2 hours before the procedure. Tablets are scored and dosage should be calculated in half-tablet increments.
Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.
Sponsor
Dechra Veterinary Products LLC
ANADA
200-490
Status
RX
Form
Chewable Tablets
Route
Oral
Composition / specifications
25 mg, 75 mg, and 100 mg of carprofen per tablet
Dogs
Indication
For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs.
Dosage
The recommended dosage for oral administration to dogs is 2 mg/lb (4.4 mg/kg) of body weight daily. The total daily dose may be administered as 2 mg/lb of body weight once daily or divided and administered as 1 mg/lb (2.2 mg/kg) twice daily. For the control of postoperative pain, administer approximately 2 hours before the procedure. Tablets are scored and dosage should be calculated in half-tablet increments.
Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.
Sponsor
Zoetis Inc.
NADA
141-053
Status
RX
Form
Caplet
Route
Oral
Species
Dog
Composition / specifications
Each caplet or chewable tablet contains 25, 75, or 100 milligrams (mg) carprofen.
Dogs
Indication
For the control of postoperative pain associated with soft tissue and orthopedic surgery. For the relief of pain and inflammation associated with osteoarthritis.
Dosage
2 milligram per pound (4.4 mg/kg) of body weight once daily or 1 milligram per pound twice daily.
Limitations
For use in dogs only. Not for use in cats. For the control of postoperative pain, administer approximately 2 hours before the procedure. Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.
Sponsor
Zoetis Inc.
NADA
141-111
Status
RX
Form
Tablet (Chewable)
Route
Oral
Species
Dog
Composition / specifications
Each caplet or chewable tablet contains 25, 75, or 100 milligrams (mg) carprofen.
Dogs
Indication
Rimadyl is indicated for the relief of pain and inflammation associated with osteoarthritis and
for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs.
Dosage
2 milligram per pound of body weight once daily or 1 milligram per pound twice daily.
Limitations
For use in dogs only. Do not use in cats.
For the control of postoperative pain, administer approximately 2 hours before the procedure
Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.
Sponsor
Dechra Veterinary Products LLC
ANADA
200-522
Status
RX
Form
Injectable Solution
Route
Subcutaneous
Species
Dog
Composition / specifications
50 mg/mL
Label highlights
Indication
For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs.
Dosage
The recommended dosage for subcutaneous administration to dogs is 2 mg/lb (4.4 mg/kg) of body weight daily. The total daily dose may be administered as either 2 mg/lb of body weight once daily or divided and administered as 1 mg/lb (2.2 mg/kg) twice daily. For control of postoperative pain, administer approximately 2 hours before the procedure.
Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.
Sponsor
Norbrook Laboratories, Ltd.
ANADA
200-595
Status
RX
Form
Chewable Tablets
Route
Oral
Species
Dog
Composition / specifications
25, 75, and 100 mg tablet strengths
Dogs
Indication
For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs.
Dosage
The recommended dosage for oral administration to dogs is 2 mg/lb (4.4 mg/kg) of body weight daily. The total daily dose may be administered as 2 mg/lb of body weight once daily or divided and administered as 1 mg/lb (2.2 mg/kg) twice daily. For the control of postoperative pain, administer approximately 2 hours before the procedure. Tablets are scored and dosage should be calculated in half-tablet increments.
Limitations
Federal Law restricts this drug to use by or on the order of a licensed veterinarian.
Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.
Sponsor
Accord Healthcare, Inc.
ANADA
200-593
Status
RX
Form
Injectable Solution
Route
Subcutaneous
Species
Dog
Composition / specifications
50 mg/mL
Dogs
Indication
For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries.
Dosage
2 mg/lb. (4.4 mg/kg) body weight once daily or 1 mg/lb. pound (2.2 mg/kg) body weight twice daily.
Limitations
For use in dogs only. Do not use in cats. Federal law restricts this drug to use by or on the order of a licensed veterinarian. For the control of postoperative pain, administer approximately 2 hours before the procedure.
Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.
Sponsor
Elanco US Inc.
ANADA
200-555
Status
RX
Form
Soft Chewable Tablet
Route
Oral
Species
Dog
Composition / specifications
25, 75, and 100 mg
Label highlights
Indication
For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs
Dosage
2 mg per pound (lb) of body weight once daily or 1 mg/lb twice daily for the control of postoperative pain; administer approximately 2 hours before procedure
Limitations
Federal Law restricts this drug to use by or on the order of a licensed veterinarian
FDA Structured Product Label from the electronic animal drug product listing directory.
Data Sources & Change Log
Every non-trivial field is expected to include provenance and update timestamps.
Official 193Clinical 7Manufacturer 0Marketing 0
Marketing/Manufacturer content exists:
1 linked manufacturer ad video are attached to this medication.
Current Field Facts
overdose_info: Overdose can cause severe GI bleeding and kidney injury. Seek emergency veterinary care. (Clinical, 2026-04-12)
overdose_info: Overdose can cause severe GI bleeding and kidney injury. Seek emergency veterinary care. (Clinical, 2026-04-11)
overdose_info: Overdose can cause severe GI bleeding and kidney injury. Seek emergency veterinary care. (Clinical, 2026-02-12)
side_effects: GI upset (vomiting/diarrhea), decreased appetite, lethargy. Rare: ulceration or liver enzyme elevations. (Clinical, 2026-04-11)
storage_handling: Store at room temperature in a dry place. (Clinical, 2026-04-12)
storage_handling: Store at room temperature in a dry place. (Clinical, 2026-04-11)
storage_handling: Store at room temperature in a dry place. (Clinical, 2026-02-12)
contraindications: Avoid combining with other NSAIDs or corticosteroids. Use caution with kidney/liver disease or GI ulcer history. (Official, 2026-04-12)
contraindications: Avoid combining with other NSAIDs or corticosteroids. Use caution with kidney/liver disease or GI ulcer history. (Official, 2026-04-11)
contraindications: Avoid combining with other NSAIDs or corticosteroids. Use caution with kidney/liver disease or GI ulcer history. (Official, 2026-02-12)
dosage_forms: Injection (Official, 2026-06-22)
dosage_forms: Injection (Official, 2026-06-22)
dosage_forms: Injection (Official, 2026-06-21)
dosage_forms: Injection (Official, 2026-06-20)
dosage_forms: Injection (Official, 2026-06-13)
dosage_forms: Injection (Official, 2026-06-12)
dosage_forms: Injection (Official, 2026-06-12)
dosage_forms: Injection (Official, 2026-06-11)
dosage_forms: Injection (Official, 2026-06-11)
dosage_forms: Injection (Official, 2026-06-10)
Recent Revisions
side_effects updated 2026-04-12 10:05 by etl_backfill • Backfilled from existing medication fields
contraindications updated 2026-04-12 10:05 by etl_backfill • Backfilled from existing medication fields
usage updated 2026-04-12 10:05 by etl_backfill • Backfilled from existing medication fields
side_effects updated 2026-04-11 10:05 by etl_backfill • Backfilled from existing medication fields
contraindications updated 2026-04-11 10:05 by etl_backfill • Backfilled from existing medication fields
usage updated 2026-04-11 10:05 by etl_backfill • Backfilled from existing medication fields
side_effects updated 2026-02-12 19:40 by etl_backfill • Backfilled from existing medication fields
contraindications updated 2026-02-12 19:40 by etl_backfill • Backfilled from existing medication fields
usage updated 2026-02-12 19:40 by etl_backfill • Backfilled from existing medication fields
FDA Products & Applications (Animal Drugs @ FDA)
Official sponsor/proprietary-name/application-status records linked by active ingredient.
Data source: FDA Animal Drugs @ FDA (public search export).
What It's For (FDA Label Highlights)
Extracted from FDA Animal Drugs @ FDA product labeling. Always confirm details with your veterinarian.
Species: Dog
Composition / specifications
25 mg, 75 mg, and 100 mg tablets
Label highlights
Indication
For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries
Dosage
The recommended dosage for oral administration to dogs is 2 mg/lb (4.4 mg/kg) of body weight daily. The total daily dose may be administered as 2 mg/lb of body weight daily or divided and administered as 1 mg/lb (2.2 mg/kg) twice daily. For the control of postoperative pain, administer approximately 2 hours before the procedure. Tablets are scored and dosage should be calculated in half-tablet increments
Limitations
Federal Law restricts this drug to use by or on the order of a licensed veterinarian
Each caplet contains 25, 75, or 100 milligrams (mg) carprofen.
Dogs
Indication
For the relief of pain and inflammation
associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries.
Dosage
2 milligram per pound of body weight once daily or 1 milligram per pound twice daily.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian.
For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs.
Dosage
2 milligram per pound (4.4 mg/kg) of body weight once daily or 1 milligram per pound twice daily.
For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs
Dosage
The recommended dosage for oral administration to dogs is 2 mg/lb (4.4 mg/kg) of body weight daily. The total daily dose may be administered as 2 mg/lb of body weight once daily or divided and administered as 1 mg/lb (2.2. mg/kg) twice daily. For the control of postoperative pain, administer approximately 2 hours before the procedure. Tablets are scored and dosage should be calculated in half-tablet increments
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian
Each caplet or chewable tablet contains 25, 75, or 100 milligrams (mg) carprofen.
Dogs
Indication
For the control of postoperative pain associated with soft tissue and orthopedic surgery. For the relief of pain and inflammation associated with osteoarthritis
Dosage
2 milligram per pound of body weight once daily or 1 milligram per pound twice daily.
Limitations
For the control of postoperative pain, administer approximately 2 hours before the procedure. Federal law restricts this drug to use by or on the order of a licensed veterinarian
For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs.
Dosage
The recommended dosage for subcutaneous administration to dogs is 2 mg/lb (4.4 mg/kg) of body weight daily. The total daily dose may be administered as either 2 mg/lb of body weight once daily or divided and administered as 1 mg/lb (2.2 mg/kg) twice daily. For control of postoperative pain, administer approximately 2 hours before the procedure.
25 mg, 37.5 mg, 50 mg, 75 mg, and 100 mg of carprofen per tablet
Dogs
Indication
For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs.
Dosage
The recommended dosage for oral administration to dogs is 2 mg/lb (4.4 mg/kg) of body weight daily. The total daily dose may be administered as 2 mg/lb of body weight once daily or divided and administered as 1 mg/lb (2.2 mg/kg) twice daily. For the control of postoperative pain, administer approximately 2 hours before the procedure. For scored tablets, dosage should be calculated in half-tablet increments.
For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs.
Dosage
The recommended dosage for subcutaneous administration to dogs is 2 mg/lb (4.4 mg/kg) of body weight daily. The total daily dose may be administered as either 2 mg/lb of body weight once daily or divided and administered as 1 mg/lb (2.2 mg/kg) twice daily. For control of postoperative pain, administer approximately 2 hours before procedure.
For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs.
Dosage
The recommended dosage for oral administration to dogs is 2 mg/lb (4.4 mg/kg) of body weight daily. The total daily dose may be administered as 2 mg/lb of body weight once daily or divided and administered as 1 mg/lb (2.2 mg/kg) twice daily. For the control of postoperative pain, administer approximately 2 hours before the procedure. For scored tablets, dosage should be calculated in half-tablet increments.
For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs.
Dosage
The recommended dosage for oral administration to dogs is 2 mg/lb of body weight daily. The total daily dose may be administered as 2 mg/lb of body weight once daily or divided and administered as 1 mg/lb twice daily. For the control of postoperative pain, administer approximately 2 hours before the procedure.
For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs.
Dosage
The recommended dosage for oral administration to dogs is 2 mg/lb of body weight daily. The total daily dose may be administered as 2 mg/lb of body weight once daily or divided and administered as 1 mg/lb twice daily. For the control of postoperative pain, administer approximately 2 hours before the procedure. Carprofen chewable tablets are scored and dosage should be calculated in half-tablet increments.
Each caplet or chewable tablet contains 25, 75, or 100 milligrams (mg) carprofen.
Dogs
Indication
Carprofen is indicated for the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries In dogs.
Dosage
2 milligram per pound of body weight once daily or 1 milligram per pound twice daily.
Limitations
For use in dogs only. Do not use in cats.
Carprofen should not be used in dogs exhibiting previous hypersensitivity to carprofen.
For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs.
Dosage
The recommended dosage for oral administration to dogs is 2 mg/lb (4.4 mg/kg) of body weight daily. The total daily dose may be administered as 2 mg/lb of body weight once daily or divided and administered as 1 mg/lb (2.2 mg/kg) twice daily. For the control of postoperative pain, administer approximately 2 hours before the procedure.
Each milliliter (mL) contains 50 milligrams (mg) of carprofen.
Label highlights
Indication
For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs.
Dosage
The recommended dosage for subcutaneous administration to dogs is 2 mg/lb (4.4 mg/kg) of body weight daily. The total daily dose may be administered as either 2 mg/lb of body weight once daily or divided and administered as 1 mg/lb (2.2 mg/kg) twice daily. For control of postoperative pain, administer approximately 2 hours before the procedure.
Limitations
Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Each milliliter of solution contains 50 milligrams carprofen.
Dogs
Indication
For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries.
Dosage
2 milligram per pound (4.4 milligrams per kilogram) body weight once daily or 1 milligram per pound (2.2 milligrams per kilogram) body weight twice daily, by subcutaneous injection.
Limitations
For use in dogs only. Do not use in cats.
Federal law restricts this drug to use by or on the order of a licensed veterinarian.
For the control of postoperative pain, administer approximately 2 hours before the procedure.
For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs.
Dosage
The recommended dosage for oral administration to dogs is 2 mg/lb (4.4 mg/kg) of body weight daily. The total daily dose may be administered as 2 mg/lb of body weight daily or divided and administered as 1 mg/lb (2.2 mg/kg) twice daily. For the control of postoperative pain, administer approximately 2 hours before the procedure.
For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs.
Dosage
The recommended dosage for oral administration to dogs is 2 mg/lb (4.4 mg/kg) of body weight daily. The total daily dose may be administered as 2 mg/lb of body weight once daily or divided and administered as 1 mg/lb (2.2 mg/kg) twice daily. For the control of postoperative pain, administer approximately 2 hours before the procedure. Tablets are scored and dosage should be calculated in half-tablet increments.
For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs.
Dosage
The recommended dosage for oral administration to dogs is 2 mg/lb (4.4 mg/kg) of body weight daily. The total daily dose may be administered as 2 mg/lb of body weight once daily or divided and administered as 1 mg/lb (2.2 mg/kg) twice daily. For the control of postoperative pain, administer approximately 2 hours before the procedure. Tablets are scored and dosage should be calculated in half-tablet increments.
Each caplet or chewable tablet contains 25, 75, or 100 milligrams (mg) carprofen.
Dogs
Indication
For the control of postoperative pain associated with soft tissue and orthopedic surgery. For the relief of pain and inflammation associated with osteoarthritis.
Dosage
2 milligram per pound (4.4 mg/kg) of body weight once daily or 1 milligram per pound twice daily.
Limitations
For use in dogs only. Not for use in cats. For the control of postoperative pain, administer approximately 2 hours before the procedure. Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Each caplet or chewable tablet contains 25, 75, or 100 milligrams (mg) carprofen.
Dogs
Indication
Rimadyl is indicated for the relief of pain and inflammation associated with osteoarthritis and
for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs.
Dosage
2 milligram per pound of body weight once daily or 1 milligram per pound twice daily.
Limitations
For use in dogs only. Do not use in cats.
For the control of postoperative pain, administer approximately 2 hours before the procedure
Federal law restricts this drug to use by or on the order of a licensed veterinarian.
For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs.
Dosage
The recommended dosage for subcutaneous administration to dogs is 2 mg/lb (4.4 mg/kg) of body weight daily. The total daily dose may be administered as either 2 mg/lb of body weight once daily or divided and administered as 1 mg/lb (2.2 mg/kg) twice daily. For control of postoperative pain, administer approximately 2 hours before the procedure.
For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs.
Dosage
The recommended dosage for oral administration to dogs is 2 mg/lb (4.4 mg/kg) of body weight daily. The total daily dose may be administered as 2 mg/lb of body weight once daily or divided and administered as 1 mg/lb (2.2 mg/kg) twice daily. For the control of postoperative pain, administer approximately 2 hours before the procedure. Tablets are scored and dosage should be calculated in half-tablet increments.
Limitations
Federal Law restricts this drug to use by or on the order of a licensed veterinarian.
For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries.
Dosage
2 mg/lb. (4.4 mg/kg) body weight once daily or 1 mg/lb. pound (2.2 mg/kg) body weight twice daily.
Limitations
For use in dogs only. Do not use in cats. Federal law restricts this drug to use by or on the order of a licensed veterinarian. For the control of postoperative pain, administer approximately 2 hours before the procedure.
For the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs
Dosage
2 mg per pound (lb) of body weight once daily or 1 mg/lb twice daily for the control of postoperative pain; administer approximately 2 hours before procedure
Limitations
Federal Law restricts this drug to use by or on the order of a licensed veterinarian
De-duplicated reaction terms grouped by body system from FDA openFDA reports (not verified; does not prove causation).
Digestive
Loss of appetite (1) • Dog
Decreased appetite (1) • Dog
Bloody diarrhoea (1) • Cat
Showing top 5 for Digestive.
Neurologic
Unsteady walking (1) • Dog
Circling - neurological disorder (1) • Dog
Showing top 5 for Neurologic.
Other
Decreased blood urea nitrogen (BUN) or creatinine (1) • Dog
Death by euthanasia (1) • Cat
Death (1) • Dog
Deafness (1) • Dog
Crust (1) • Dog
Show more (22)
Cough, productive (1) • Dog
Cough (1) • Dog
Corneal ulcer (1) • Dog
Corneal oedema (1) • Dog
Corneal disorder NOS (1) • Dog
Constipation (1) • Dog
Conjunctivitis (1) • Dog
Collapse NOS (1) • Dog
Bumps on skin (1) • Dog
Blood loss NOS (1) • Dog
Blood in urine (1) • Dog
Bacterial skin infection NOS (1) • Dog
Arthritis (1) • Dog
Anaphylaxis (1) • Dog
Anal and rectal disorder NOS (1) • Dog
Anaemia NOS (1) • Cat
Active urine sediment (1) • Dog
Accidental exposure (1) • Dog
Abnormal radiograph finding (1) • Dog
Abnormal histology NOS (1) • Dog
Abnormal cytology (1) • Dog
Abdominal pain (1) • Dog
Showing top 5 for Other.
Data source: FDA openFDA Animal & Veterinary adverse event reports.
Adverse Event Case Summaries (openFDA)
These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.
Lack of efficacy - NOSMusculoskeletal disorder NOS
Outcomes: Ongoing
Dog, Crossbred Canine/dog, Female, 10 year, 41.277 kilogram • Drug: MSK, Tablet, chewable, Oral, Dose: 3000 Milligram per animal • Reactions: Death by euthanasia, Accidental exposure, Overdose, Vomiting, Loss of appetite… • Outcome: Euthanized
Report ID: USA-USFDACVM-2025-US-075175
Serious AE: Yes
Treated For AE: Yes
Sex: Female
Age: 10.00 Year
Weight: 41.277 Kilogram
Case-reported brand: MSK
Case-reported manufacturer: MSK
Route: Oral
Form: Tablet, chewable
Dose: 3000 Milligram per animal
Reactions Reported:
Death by euthanasiaAccidental exposureOverdoseVomitingLoss of appetitePolydipsiaGeneralised weaknessTiredness (lethargy)Dry mucous membraneUnsteady walking (ataxia)Vomiting foamUnsteady gait
Data source: FDA openFDA Animal & Veterinary adverse event reports.
Overdose Information
Overdose can cause severe GI bleeding and kidney injury. Seek emergency veterinary care.
Storage & Handling
Store at room temperature in a dry place.
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