Gabapentin administration tips
How owners can administer doses safely.
Roxee Medication Guide
Gabapentin
Medication reference facts with explicit FDA-approval, off-label, source-limited, and safety context. Roxee does not sell, prescribe, or dispense medications.
Both
Reference partial
Not FDA-approved for animals
Multiple FDA labelers
Official label facts
Owner quick guide first
Veterinary professional?
Showing simplified owner view. Switch to Vet View for full technical detail.
Some reference facts for this medication are still being verified.
Not FDA-approved as an animal drug.
No FDA-approved animal-drug application is linked for this record. It may represent extra-label, human-drug, bulk-compounding, export-only, or otherwise unapproved animal-use source data; use only under veterinarian direction.
Do not start, stop, or change treatment without your veterinarian.
Data freshness
Reference facts
Reference refreshed
Jun 22, 2026, 10:45 a.m.
Roxee has a partial reference profile for this medication. Some primary facts still need verification.
FDA applications
FDA application data refreshed
Jun 22, 2026, 10:41 a.m.
Sponsor, product, and application records imported from Animal Drugs @ FDA.
Safety reports
Safety data refreshed
Jun 22, 2026, 10:42 a.m.
openFDA reaction terms and case summaries are supporting evidence, not proof of causality.
Source timing details
Source timing details
-
Reference facts:
Source Roxee
| Refreshed Jun 22, 2026, 10:45 AM UTC
The reference fact projection used for browse cards and quick facts.
-
Animal Drug Product Listing Directory (NDC):
Source FDA
| Refreshed Jun 22, 2026, 10:41 AM UTC
Package/product NDCs from FDA’s electronic listing directory (XLS).
- openFDA reaction terms: Source FDA openFDA | Refreshed Jun 22, 2026, 10:45 AM UTC
- openFDA case summaries: Source FDA openFDA | Refreshed Jun 22, 2026, 10:45 AM UTC
Image coming soon
Gabapentin
Gabapentin
Drug type: Generic ingredient • Branded profile • Not FDA-approved for animals
Both
86% reference complete
Species: Both
Approval status: Not FDA-approved as an animal drug. No FDA-approved animal-drug application is linked for this record. It may represent extra-label, human-drug, bulk-compounding, export-only, or otherwise unapproved animal-use source data; use only under veterinarian direction.
Medication Snapshot
Merged from the current Roxee medication system with field-level provenance, freshness, and completeness tracking.
Gabapentin
Used for neuropathic pain and as an adjunct for seizure control; also used for situational anxiety/sedation in some cases. Species commonly shown: Both.
Generic name
Gabapentin
Brand names
SolutitionKits, Gabapentin
Manufacturer
Multiple FDA labelers
Species
Both
Completeness
86%
Validation
Incomplete
Brand names
SolutitionKits
Gabapentin
Indications / Uses
Used for neuropathic pain and as an adjunct for seizure control; also used for situational anxiety/sedation in some cases.
Administration / How To Give
Oral
Storage
Store at room temperature.
Warnings / Contraindications
Use caution with kidney disease; dose adjustments may be needed.
- Use caution with kidney disease; dose adjustments may be needed.
Side Effects
Sedation, ataxia, mild GI upset.
FAQ
Both
Store at room temperature.
Related Medications
Related Conditions
Source Transparency
- Verified source: https://www.roxee.ai/meds/
- Verified source: https://animaldrugsatfda.fda.gov
- Verified source: https://animaldrugsatfda.fda.gov/adafda/views/#/search
- Verified source: https://api.fda.gov/animalandveterinary/event.json
- Verified source: https://www.roxee.ai/conditions/
- Verified source: /static/meds/images/gabapentin.jpg
- Last refreshed: Jun 22, 2026, 10:45 a.m.
- Last verified: Apr 15, 2026, 10:04 a.m.
- Validation status: Incomplete
Add to My Pet's Medications
Choose a pet, confirm current or past, and optionally add reminder notes.
Sign in to save this medication to your pet profile.
Sign in to continueVideos
Video education and manufacturer materials for Gabapentin.
Educational Videos
Manufacturer Videos
Gabapentin manufacturer spotlight
Promotional
Disclosure:
Manufacturer-linked promotional content. Educational sections should be prioritized for clinical context.
Manufacturer-provided informational segment.
Pet Owner Quick Guide
Start here first for the safest next-step summary before the deeper medication detail.
Used for:
Used for neuropathic pain and as an adjunct for seizure control; also used for situational anxiety/sedation in some cases.
Dosing note:
Exact dosing depends on your pet's species, weight, and health status. Use your veterinarian's instructions for the exact dose and schedule.
What to watch for:
- Use caution with kidney disease
- dose adjustments may be needed
- wobbly/unsteady walking (1 reports)
- Loss of appetite (1 reports)
- Bloody diarrhoea (1 reports)
When to call the vet:
- Repeated vomiting or diarrhea.
- Severe lethargy (hard to wake, very low energy).
- Collapse or fainting.
- Trouble breathing.
- Facial swelling or hives.
- Blood in vomit or stool.
What to tell or ask your vet today:
- Is this medicine the right fit for my pet’s current symptoms?
- Which warning signs mean I should call back right away?
- How should I handle missed doses or refusal to take the medicine?
Research brief
Medication Research Insights
A source-aware map of what to know, what is uncertain, and what to verify with your veterinarian.
What to know
Evidence-backed context
Limited
Roxee has limited cited overview evidence for Gabapentin; use the official documents and your veterinarian's instructions for product-specific decisions.
Source: openFDA case USA-USFDACVM-2025-US-070810
Safety signal coverage
Reported signals
32 tracked reaction signals; 32 reported cases; 25 serious reports; 2 species groups. These are reporting and label-derived signals for interpretation with a veterinarian.
Source: openFDA case USA-USFDACVM-2025-US-070810
Interpretation guardrail
Not causation
Adverse-event reports help form a watch list, but they do not prove the medication caused the reaction and they are not a risk ranking between medications.
Evidence tension
Stronger signal
Label / review
Official labels, package inserts, and reviewed summaries carry more weight than isolated reports.
Source: openFDA case USA-USFDACVM-2025-US-070810
Weaker signal
Reported data
Case reports and openFDA terms are useful for pattern awareness, but they are incomplete, can include multiple exposures, and do not estimate an individual pet's probability of harm.
Reaction signal map
Most reported reactions
Top terms
Unsteady walking (ataxia) (1 reports), Loss of appetite (1 reports), Bloody diarrhoea (1 reports), Blood in vomit (1 reports), Blood in urine (1 reports)
Body systems represented
Signal grouping
Digestive (3), Skin & allergy (3), Neurologic (1), Behavior (3)
Species and breed lens
Species represented in reports
Species lens
Dog (18 reports), Cat (14 reports)
Breed metadata in reports
Metadata only
Shepherd Dog - German (2), Domestic Shorthair (2), Siamese (1), Siberian Husky (1). These are report metadata, not proof that a breed is at higher risk.
What your vet may verify
Fit for this patient
Vet check
Verify whether Gabapentin fits the pet's species, current diagnosis, age, weight, organ status, pregnancy/lactation status, and concurrent medications.
Evidence limitations
Evidence review
Separate label-backed warnings from adverse-event reports and owner observations before changing the plan.
What to watch next
Watch list
Owner-safe
Use caution with kidney disease, dose adjustments may be needed, wobbly/unsteady walking, Loss of appetite, Bloody diarrhoea
Call sooner if
Escalation
Repeated vomiting or diarrhea. Severe lethargy (hard to wake, very low energy). Collapse or fainting.
Bottom line: Use this Gabapentin brief as a structured watch list and source map, not as a reason to start, stop, or change treatment without your veterinarian.
Vet source depth
- openFDA case USA-USFDACVM-2025-US-070810 · adverse_reaction · adverse reactions
- Medication contraindications · safety_warning · warnings contraindications
- Structured Product Label · document · documents
- Structured Product Label · document · documents
- Structured Product Label · document · documents
- Structured Product Label · document · documents
Evidence
Review status / Updated / Sources
Review status: Clinical reviewer not listed
Updated: April 15, 2026, 10:04 AM UTC
Sources:
- Medication contraindications · safety_warning
- openFDA case USA-USFDACVM-2025-US-070810 · adverse_reaction
- Structured Product Label · document
- Structured Product Label · document
- Structured Product Label · document
Safety & side effects
Side effects to monitor:
- Use caution with kidney disease
- dose adjustments may be needed
- wobbly/unsteady walking
- Loss of appetite
- Bloody diarrhoea
Most reported reactions:
- Unsteady walking (ataxia) (1 reports)
- Loss of appetite (1 reports)
- Bloody diarrhoea (1 reports)
Emergency warning signs:
- Repeated vomiting or diarrhea.
- Severe lethargy (hard to wake, very low energy).
- Collapse or fainting.
- Trouble breathing.
Vet Fast Scan
Source-backed clinical checkpoints for quick review.
FDA-labeled species
Not linked yet
Indication / use
Used for neuropathic pain and as an adjunct for seizure control; also used for situational anxiety/sedation in some cases.
Form / route / dose
Confirm product label and patient-specific plan.
Warnings
- High: Use caution with kidney disease; dose adjustments may be needed.
Adverse-event caveat
openFDA adverse-event cases are reported signals. They are not verified, do not prove causation, and do not estimate a pet's individual risk.
Source docs
- Gabapentin SPL SPL
- Gabapentin SPL SPL
- SolutitionKits SPL SPL
Quick Facts
Official label facts first, then secondary summaries. Marketing content is separated below.
Species: Both
Manufacturer: Multiple FDA labelers
Identifiers:
NDC Package: 46144-600-01
NDC Package: 62157-711-01
NDC Package: 73377-176-01
NDC Package: 86032-041-01
NDC Product: 46144
NDC Product: 62157
NDC Product: 73377
NDC Product: 86032
Warnings / Contraindications
Use caution with kidney disease; dose adjustments may be needed.
- High: Use caution with kidney disease; dose adjustments may be needed.
Source metadata:
- https://animaldrugsatfda.fda.gov · safety_warning · Medication contraindications
Adverse Reactions
Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.
Reported case explorer
Filter stored openFDA reports by pet and report attributes. Counts describe reports in this data set, not risk.
openFDA adverse-event cases are reported signals. They are not verified, do not prove causation, and do not estimate a pet's individual risk.
Stored reports
80
Matching reports
4
Active filters
2
Drill into common report signals
Showing up to 50 matching reports.
USA-USFDACVM-2025-US-073901
Received 2025-12-19 · MSK · MSK
- Species
- Dog
- Breed
- Terrier - Bull - American Pit
- Size / weight
- 50-99 lb (37 Kilogram)
- Age
- 4-7 years (7 Year)
- Sex
- Male Neutered
- Region
- USA
- Reactions
- Loose stoolEmesis (multiple)Decreased appetiteDecreased drinkingMedication error NOSLack of efficacy - NOS
- Body systems
- OtherDigestiveEffectiveness
- Outcomes
- Ongoing
USA-USFDACVM-2025-US-074363
Received 2025-12-14 · MSK · MSK
- Species
- Dog
- Breed
- Retriever - Labrador
- Size / weight
- 50-99 lb (37.8 Kilogram)
- Age
- 8+ years (11.3 Year)
- Sex
- Male Neutered
- Region
- USA
- Reactions
- WoundLick granulomaExternal ear disorder NOSPerianal inflammationMusculoskeletal disorder NOSHeavy breathingPantingDecreased appetiteScootingActive urine sedimentFungal skin infection NOSSkin lesion NOSLack of efficacy - NOS
- Body systems
- OtherDigestiveEffectiveness
- Outcomes
- Ongoing
USA-USFDACVM-2025-US-075182
Received 2025-11-24 · MSK · MSK
- Species
- Cat
- Breed
- Domestic Shorthair
- Size / weight
- 10-24 lb (4.76 Kilogram)
- Age
- 8+ years (11 Year)
- Sex
- Male Neutered
- Region
- USA
- Reactions
- Cold feeling to the touchDecreased appetiteLack of efficacy - NOSBehavioural disorder NOSVomitingRenal disorder NOSLethargy (see also Central nervous system depression in Neurological)Elevated renal parametersArthritisReluctant to moveWeight gainWobblinessDental diseaseRespiratory tract infection NOSAnaemia NOSElevated creatinineHypercalcaemiaFeverDehydrationDiarrhoeaDecreased haematocritDecreased red blood cell countDigestive tract disorder NOSSicknessDistressDiabetesDecreased body temperatureDeath by euthanasia
- Body systems
- OtherDigestiveEffectivenessBehaviorNeurologic
- Outcomes
- Euthanized
USA-USFDACVM-2025-US-067364
Received 2025-11-14 · MSK · MSK
- Species
- Cat
- Breed
- Domestic Shorthair
- Size / weight
- 10-24 lb (6.804 Kilogram)
- Age
- 8+ years (14 Year)
- Sex
- Female Unknown
- Region
- USA
- Reactions
- DehydrationEmesis (multiple)Elevated cholesterol (total)Abnormal radiograph findingLack of efficacy - NOSWeaknessUrinary incontinenceAtaxiaDullRecumbencyIncreased coagulation timeElevated aspartate aminotransferase (AST)Elevated creatinineHypokalaemiaElevated gamma-glutamyl transferase (GGT)Elevated triglycerideBlood in urineHypothermiaDisseminated intravascular coagulationCardiorespiratory arrestDeathIntentional misuseShockDistension of abdomen
- Body systems
- OtherDigestiveEffectivenessNeurologic
- Outcomes
- Died
Tap or hover a reaction to see what it means in plain language.
Tracked signals
32
Reported cases
32
Serious reports
25
Species represented
2
Grouped by Body System
Digestive (3)
· Loss of appetite, Bloody diarrhoea, Blood in vomit
Skin & allergy (3)
· Hair loss, Application site hair loss, Alopecia NOS
Neurologic (1)
· Unsteady walking (ataxia)
Behavior (3)
· Biting -aggression, Behavioral disorder (unspecified), Anxiety
Other (22)
· Blood in urine, Bladder distension, Balance problem
Most Reported Reactions
| Reaction | Body system | Cases | Species | Serious cases |
|---|---|---|---|---|
| Neurologic | 1 | Cat | 1 | |
| Digestive | 1 | Cat | 1 | |
| Digestive | 1 | Cat | 1 | |
| Digestive | 1 | Cat | 1 | |
| Other | 1 | Dog | 1 | |
| Other | 1 | Cat | 1 | |
| Behavior | 1 | Dog | 1 | |
| Behavior | 1 | Cat | 1 |
Species coverage: Dog (18) Cat (14)
View detailed reaction table
| Reaction | Body system | Species | Seriousness | Frequency | Reports |
|---|---|---|---|---|---|
| Neurologic | Cat | Serious | - | 1 | |
| Digestive | Cat | Serious | - | 1 | |
| Skin & allergy | Dog | Non-serious | - | 1 | |
| Digestive | Cat | Serious | - | 1 | |
| Digestive | Cat | Serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Behavior | Dog | Serious | - | 1 | |
| Behavior | Cat | Serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Dog | Non-serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Other | Dog | Non-serious | - | 1 | |
| Skin & allergy | Cat | Non-serious | - | 1 | |
| Other | Cat | Non-serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Behavior | Dog | Serious | - | 1 | |
| Other | Cat | Non-serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Skin & allergy | Cat | Serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Dog | Non-serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Dog | Serious | - | 1 |
Source metadata:
- https://api.fda.gov/animalandveterinary/event.json · adverse_reaction · openFDA case USA-USFDACVM-2025-US-070810
Storage & Handling
Store at room temperature.
Source Documents
The most useful source links appear first; full previews and metadata stay in the veterinary/professional layer.
Use original documents to confirm product-specific warnings, ingredients, and handling details with your veterinarian.
Gabapentin SPL
SPL · Structured Product Label
Gabapentin SPL
SPL · Structured Product Label
SolutitionKits SPL
SPL · Structured Product Label
Full source previews and metadata remain in the veterinary/professional layer.
Owner handouts
0No owner handouts linked yet.
Official label / PI
0No official label or package insert links yet.
SPL
4FOI
0No FOI links yet.
Gabapentin SPL
SPL · Structured Product Label
FDA Structured Product Label XML for Gabapentin. Use the source link for the full official labeling record.
Gabapentin SPL
SPL · Structured Product Label
FDA Structured Product Label XML for Gabapentin. Use the source link for the full official labeling record.
SolutitionKits SPL
SPL · Structured Product Label
FDA Structured Product Label XML for SolutitionKits. Use the source link for the full official labeling record.
GABAPENTIN SPL
SPL · Structured Product Label
FDA Structured Product Label XML for GABAPENTIN. Use the source link for the full official labeling record.
Source metadata:
- https://www.accessdata.fda.gov/spl/data/54945492-2e86-4f6d-99e0-d4f492ab0dc0/54945492-2e86-4f6d-99e0-d4f492ab0dc0.xml · document · Structured Product Label
- https://www.accessdata.fda.gov/spl/data/de14dc38-395f-420b-89b9-f3c57e195149/de14dc38-395f-420b-89b9-f3c57e195149.xml · document · Structured Product Label
- https://www.accessdata.fda.gov/spl/data/fc8d67a9-6118-481c-a1e4-53269e18b31d/fc8d67a9-6118-481c-a1e4-53269e18b31d.xml · document · Structured Product Label
- https://www.accessdata.fda.gov/spl/data/346c35fb-8599-4556-9804-a4452af8bb91/346c35fb-8599-4556-9804-a4452af8bb91.xml · document · Structured Product Label
Veterinary reference (advanced)
Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.
At a Glance
Quick facts and links to official labeling and safety signals.
Data freshness
-
Reference facts:
Source Roxee
| Refreshed Jun 22, 2026, 10:45 AM UTC
The reference fact projection used for browse cards and quick facts.
-
Animal Drug Product Listing Directory (NDC):
Source FDA
| Refreshed Jun 22, 2026, 10:41 AM UTC
Package/product NDCs from FDA’s electronic listing directory (XLS).
- openFDA reaction terms: Source FDA openFDA | Refreshed Jun 22, 2026, 10:45 AM UTC
- openFDA case summaries: Source FDA openFDA | Refreshed Jun 22, 2026, 10:45 AM UTC
Official (FDA)
Identity: Generic ingredient
• FDA branded products available
Official FDA brands:
GABAPENTIN
Gabapentin
SolutitionKits
Manufacturer mapping:
Multiple FDA labelers
Case-reported brands (openFDA):
MSK
Catalog species: Both
NDC:
Packages
46144-600-01
62157-711-01
73377-176-01
86032-041-01
•
Products
46144
62157
73377
86032
Explore
Related conditions:
Pain (acute, chronic)
Linked using:
Usage_Inferred (0.78)
Diagnosis Codes
Diagnosis-code mappings are not available for this medication yet.
Counseling and Monitoring Highlights
Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.
Owner-facing counseling points
- Use caution with kidney disease; dose adjustments may be needed. (Contraindication, High)
Top reaction signals
Unsteady walking (ataxia) (1)
Loss of appetite (1)
Bloody diarrhoea (1)
Blood in vomit (1)
Blood in urine (1)
Bladder distension (1)
Biting -aggression (1)
Behavioral disorder (unspecified) (1)
Identifiers & Packages
Normalized identifiers (NDC/NADA/ANADA) and package metadata from regulator listings.
Identifiers
NDC Package: 46144-600-01
NDC Package: 62157-711-01
NDC Package: 73377-176-01
NDC Package: 86032-041-01
NDC Product: 46144
NDC Product: 62157
NDC Product: 73377
NDC Product: 86032
| Package NDC | Product NDC | Form / Route | Status |
|---|---|---|---|
| 46144-600-01 | 46144 | - | |
| 62157-711-01 | 62157 | - | |
| 73377-176-01 | 73377 | - | |
| 86032-041-01 | 86032 | - |
Enriched Documents
Documents are tiered by source trust: Official, Clinical, Manufacturer, Marketing.
-
Gabapentin SPL
• Structured Product Label • Official
FDA Structured Product Label from the electronic animal drug product listing directory.
-
Gabapentin SPL
• Structured Product Label • Official
FDA Structured Product Label from the electronic animal drug product listing directory.
-
SolutitionKits SPL
• Structured Product Label • Official
FDA Structured Product Label from the electronic animal drug product listing directory.
-
GABAPENTIN SPL
• Structured Product Label • Official
FDA Structured Product Label from the electronic animal drug product listing directory.
Data Sources & Change Log
Every non-trivial field is expected to include provenance and update timestamps.
Official 4
Clinical 120
Manufacturer 0
Marketing 0
Marketing/Manufacturer content exists: 1 linked manufacturer ad video are attached to this medication.
Current Field Facts
- contraindications: Use caution with kidney disease; dose adjustments may be needed. (Clinical, 2026-06-22)
- contraindications: Use caution with kidney disease; dose adjustments may be needed. (Clinical, 2026-06-22)
- contraindications: Use caution with kidney disease; dose adjustments may be needed. (Clinical, 2026-06-21)
- contraindications: Use caution with kidney disease; dose adjustments may be needed. (Clinical, 2026-06-20)
- contraindications: Use caution with kidney disease; dose adjustments may be needed. (Clinical, 2026-06-13)
- contraindications: Use caution with kidney disease; dose adjustments may be needed. (Clinical, 2026-06-12)
- contraindications: Use caution with kidney disease; dose adjustments may be needed. (Clinical, 2026-06-12)
- contraindications: Use caution with kidney disease; dose adjustments may be needed. (Clinical, 2026-06-11)
- contraindications: Use caution with kidney disease; dose adjustments may be needed. (Clinical, 2026-06-11)
- contraindications: Use caution with kidney disease; dose adjustments may be needed. (Clinical, 2026-06-10)
- contraindications: Use caution with kidney disease; dose adjustments may be needed. (Clinical, 2026-06-08)
- contraindications: Use caution with kidney disease; dose adjustments may be needed. (Clinical, 2026-06-07)
- contraindications: Use caution with kidney disease; dose adjustments may be needed. (Clinical, 2026-06-06)
- contraindications: Use caution with kidney disease; dose adjustments may be needed. (Clinical, 2026-06-05)
- contraindications: Use caution with kidney disease; dose adjustments may be needed. (Clinical, 2026-06-04)
- contraindications: Use caution with kidney disease; dose adjustments may be needed. (Clinical, 2026-06-03)
- contraindications: Use caution with kidney disease; dose adjustments may be needed. (Clinical, 2026-06-02)
- contraindications: Use caution with kidney disease; dose adjustments may be needed. (Clinical, 2026-06-01)
- contraindications: Use caution with kidney disease; dose adjustments may be needed. (Clinical, 2026-06-01)
- contraindications: Use caution with kidney disease; dose adjustments may be needed. (Clinical, 2026-05-31)
Recent Revisions
- side_effects updated 2026-06-22 10:45 by etl_backfill • Backfilled from existing medication fields
- contraindications updated 2026-06-22 10:45 by etl_backfill • Backfilled from existing medication fields
- usage updated 2026-06-22 10:45 by etl_backfill • Backfilled from existing medication fields
- side_effects updated 2026-06-22 10:04 by etl_backfill • Backfilled from existing medication fields
- contraindications updated 2026-06-22 10:04 by etl_backfill • Backfilled from existing medication fields
- usage updated 2026-06-22 10:04 by etl_backfill • Backfilled from existing medication fields
- side_effects updated 2026-06-21 05:18 by etl_backfill • Backfilled from existing medication fields
- contraindications updated 2026-06-21 05:18 by etl_backfill • Backfilled from existing medication fields
- usage updated 2026-06-21 05:18 by etl_backfill • Backfilled from existing medication fields
- side_effects updated 2026-06-20 20:58 by etl_backfill • Backfilled from existing medication fields
- contraindications updated 2026-06-20 20:58 by etl_backfill • Backfilled from existing medication fields
- usage updated 2026-06-20 20:58 by etl_backfill • Backfilled from existing medication fields
- side_effects updated 2026-06-13 11:33 by etl_backfill • Backfilled from existing medication fields
- contraindications updated 2026-06-13 11:33 by etl_backfill • Backfilled from existing medication fields
- usage updated 2026-06-13 11:33 by etl_backfill • Backfilled from existing medication fields
- side_effects updated 2026-06-12 10:42 by etl_backfill • Backfilled from existing medication fields
- contraindications updated 2026-06-12 10:42 by etl_backfill • Backfilled from existing medication fields
- usage updated 2026-06-12 10:42 by etl_backfill • Backfilled from existing medication fields
- side_effects updated 2026-06-12 10:04 by etl_backfill • Backfilled from existing medication fields
- contraindications updated 2026-06-12 10:04 by etl_backfill • Backfilled from existing medication fields
FDA Products & Applications (Animal Drugs @ FDA)
Official sponsor/proprietary-name/application-status records linked by active ingredient.
| Product | Sponsor | Application | Status | Published |
|---|
Data source: FDA Animal Drugs @ FDA (public search export).
Usage
Used for neuropathic pain and as an adjunct for seizure control; also used for situational anxiety/sedation in some cases.
Contraindications
Use caution with kidney disease; dose adjustments may be needed.
Side Effects
Sedation, ataxia, mild GI upset.
Source: FDA openFDA • Reference
Top Reported Reactions (openFDA)
De-duplicated reaction terms grouped by body system from FDA openFDA reports (not verified; does not prove causation).
Digestive
Loss of appetite (1)
• Cat
Bloody diarrhoea (1)
• Cat
Blood in vomit (1)
• Cat
Showing top 5 for Digestive.
Skin & allergy
Hair loss (1)
• Dog
Application site hair loss (1)
• Cat
Alopecia NOS (1)
• Cat
Showing top 5 for Skin & allergy.
Neurologic
Unsteady walking (1)
• Cat
Showing top 5 for Neurologic.
Behavior
Biting -aggression (1)
• Dog
Behavioral disorder (1)
• Cat
Anxiety (1)
• Dog
Showing top 5 for Behavior.
Other
Blood in urine (1)
• Dog
Bladder distension (1)
• Cat
Balance problem (1)
• Dog
Bacterial skin infection NOS (1)
• Dog
Azotaemia (1)
• Cat
Show more (17)
Arthritis (1)
• Cat
Arrhythmia (1)
• Dog
Application site excoriation (1)
• Cat
Apnoea (1)
• Dog
Anisocoria (1)
• Cat
Angioedema (1)
• Dog
Anaphylaxis (1)
• Dog
Anaemia NOS (1)
• Cat
Agitation (1)
• Dog
Active urine sediment (1)
• Dog
Abnormal ultrasound finding (1)
• Dog
Abnormal tail posture (1)
• Dog
Abnormal radiograph finding (1)
• Cat
Abnormal histology NOS (1)
• Dog
Abnormal cytology (1)
• Dog
Abdominal pain (1)
• Dog
Abdominal discomfort (1)
• Dog
Showing top 5 for Other.
Data source: FDA openFDA Animal & Veterinary adverse event reports.
Adverse Event Case Summaries (openFDA)
These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.
Dog, Shepherd Dog - German, Female, 11 year, 20.865 kilogram • Drug: MSK, Unassigned, Unknown, Dose: 200 Milligram per animal, Frequency: 12 per hour • Reactions: Vomiting, Not eating, Tiredness (lethargy), Reluctant to move, Seizure NOS • Outcome: Ongoing
- Report ID: USA-USFDACVM-2025-US-075421
- Serious AE: Yes
- Treated For AE: No
- Sex: Female
- Age: 11.00 Year
- Weight: 20.865 Kilogram
- Case-reported brand: MSK
- Case-reported manufacturer: MSK
- Route: Unknown
- Form: Unassigned
- Dose: 200 Milligram per animal
- Frequency: 12 per hour
Reactions Reported:
Vomiting
Not eating
Tiredness (lethargy)
Reluctant to move
Seizure NOS
Outcomes: Ongoing
Cat, Domestic Shorthair, Male, 7 year, 8.618 kilogram • Drug: MSK, Unassigned, Oral • Reactions: Injection site hair loss, Reddening of the skin, Weight loss, Skin lesion NOS, Wound… • Outcome: Ongoing
- Report ID: USA-USFDACVM-2025-US-075379
- Serious AE: Yes
- Treated For AE: Yes
- Sex: Male
- Age: 7.00 Year
- Weight: 8.618 Kilogram
- Case-reported brand: MSK
- Case-reported manufacturer: MSK
- Route: Oral
- Form: Unassigned
Reactions Reported:
Injection site hair loss
Reddening of the skin
Weight loss
Skin lesion NOS
Wound
Abnormal cytology
Discomfort NOS
Skin necrosis
Itching
Facial swelling (possible allergy)
Facial rash
Outcomes: Ongoing
Cat, Siamese, Male, 15 year, 3.88 kilogram • Drug: MSK, Unknown • Reactions: Lack of efficacy - NOS, Urinary tract infection, Behavioral disorder (unspecified), Decreased haematocrit, Oliguria • Outcome: Outcome Unknown
- Report ID: USA-USFDACVM-2025-US-075223
- Serious AE: Yes
- Treated For AE: Yes
- Sex: Male
- Age: 15.00 Year
- Weight: 3.880 Kilogram
- Case-reported brand: MSK
- Case-reported manufacturer: MSK
- Route: Unknown
Reactions Reported:
Lack of efficacy - NOS
Urinary tract infection
Behavioral disorder (unspecified)
Decreased haematocrit
Oliguria
Outcomes: Outcome Unknown
Dog, Siberian Husky, Female, 11 year, 26.58 kilogram • Drug: MSK, Oral, Dose: 200 Milligram per animal • Reactions: Clonic seizure, Biting -aggression, Partial blindness, Seizure NOS, Foaming at the mouth… • Outcome: Ongoing
- Report ID: USA-USFDACVM-2025-US-075044
- Serious AE: Yes
- Treated For AE: Yes
- Sex: Female
- Age: 11.00 Year
- Weight: 26.580 Kilogram
- Case-reported brand: MSK
- Case-reported manufacturer: MSK
- Route: Oral
- Dose: 200 Milligram per animal
Reactions Reported:
Clonic seizure
Biting -aggression
Partial blindness
Seizure NOS
Foaming at the mouth
Oral bleeding
Tiredness (lethargy)
Wobbliness
Unable to focus
Urination
Lateral recumbency
Vocalisation
Balance problem
Staring
Elevated alanine aminotransferase
Elevated serum alkaline phosphatase
Outcomes: Ongoing
Cat, Domestic Shorthair, Female, 11 year, 4.754 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Miliary dermatitis, Excoriation • Outcome: Ongoing
- Report ID: USA-USFDACVM-2025-US-075455
- Serious AE: Yes
- Treated For AE: Yes
- Sex: Female
- Age: 11.00 Year
- Weight: 4.754 Kilogram
- Case-reported brand: MSK
- Case-reported manufacturer: MSK
- Route: Unknown
- Form: Unassigned
Reactions Reported:
Miliary dermatitis
Excoriation
Outcomes: Ongoing
Dog, Bulldog - English, Female, 11.2 year, 29.94 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Urinary incontinence • Outcome: Ongoing
- Report ID: USA-USFDACVM-2025-US-075305
- Serious AE: No
- Treated For AE: No
- Sex: Female
- Age: 11.20 Year
- Weight: 29.940 Kilogram
- Case-reported brand: MSK
- Case-reported manufacturer: MSK
- Route: Unknown
- Form: Unassigned
Reactions Reported:
Urinary incontinence
Outcomes: Ongoing
Dog, Shepherd Dog - German, Female, 10.9 year, 44.45 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Lack of efficacy - NOS, Seizure NOS, Other abnormal test result NOS, Unsteady walking (ataxia), Musculoskeletal disorder NOS… • Outcome: Ongoing
- Report ID: USA-USFDACVM-2025-US-075291
- Serious AE: Yes
- Treated For AE: Yes
- Sex: Female
- Age: 10.90 Year
- Weight: 44.450 Kilogram
- Case-reported brand: MSK
- Case-reported manufacturer: MSK
- Route: Unknown
- Form: Unassigned
Reactions Reported:
Lack of efficacy - NOS
Seizure NOS
Other abnormal test result NOS
Unsteady walking (ataxia)
Musculoskeletal disorder NOS
Elevated serum alkaline phosphatase
Outcomes: Ongoing
Dog, ['Retriever - Golden', 'Beagle', 'Chow Chow'], Male, 11 year, 19.504 kilogram • Drug: MSK, Capsule, Oral • Reactions: Unsteady walking (ataxia), Vestibular disorder NOS, Weight loss, Head tilt - neurological disorder, Low vision… • Outcome: Ongoing
- Report ID: USA-USFDACVM-2025-US-075189
- Serious AE: Yes
- Treated For AE: Yes
- Sex: Male
- Age: 11.00 Year
- Weight: 19.504 Kilogram
- Case-reported brand: MSK
- Case-reported manufacturer: MSK
- Route: Oral
- Form: Capsule
Reactions Reported:
Unsteady walking (ataxia)
Vestibular disorder NOS
Weight loss
Head tilt - neurological disorder
Low vision
Urinary incontinence
Unable to rise
Urinary tract infection
Polydipsia
Horizontal nystagmus
Generalised weakness
Depression
Outcomes: Ongoing
Data source: FDA openFDA Animal & Veterinary adverse event reports.
Overdose Information
Overdose can cause severe sedation, loss of coordination, muscle tremors, and respiratory depression. Emergency care: IV fluids, monitoring.
Storage & Handling
Store at room temperature.
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Medical Disclaimer: The medication details provided on Roxee are for informational purposes only and are not a substitute for professional veterinary advice. Always consult your veterinarian about your pet's specific needs.