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Roxee Medication Guide
Medication reference facts with explicit FDA-approval, off-label, source-limited, and safety context. Roxee does not sell, prescribe, or dispense medications.
Veterinary professional?
Roxee has a partial reference profile for this medication. Some primary facts still need verification.
Sponsor, product, and application records imported from Animal Drugs @ FDA.
openFDA reaction terms and case summaries are supporting evidence, not proof of causality.
Drug type: Generic ingredient • Branded profile • Not FDA-approved for animals
Species: Both
Approval status: Not FDA-approved as an animal drug. No FDA-approved animal-drug application is linked for this record. It may represent extra-label, human-drug, bulk-compounding, export-only, or otherwise unapproved animal-use source data; use only under veterinarian direction.
Merged from the current Roxee medication system with field-level provenance, freshness, and completeness tracking.
Senvelgo (velagliflozin oral solution) is approved in cats for control of hyperglycemia associated with diabetes mellitus. Species commonly shown: Both.
Senvelgo (velagliflozin oral solution) is approved in cats for control of hyperglycemia associated with diabetes mellitus.
Top reported reactions (openFDA): Vomiting, Lethargy (see also Central nervous system depression in 'Neurological'), Diarrhoea, Death by euthanasia, Seizure NOS, Decreased appetite.
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Used for:
Your vet decides this. Here's what owners typically ask/watch for.
Dosing note:
Exact dosing depends on your pet's species, weight, and health status. Use your veterinarian's instructions for the exact dose and schedule.
What to watch for:
When to call the vet:
What to tell or ask your vet today:
A source-aware map of what to know, what is uncertain, and what to verify with your veterinarian.
Roxee has limited cited overview evidence for Glucosamine; use the official documents and your veterinarian's instructions for product-specific decisions.
32 tracked reaction signals; 32 reported cases; 27 serious reports; 2 species groups. These are reporting and label-derived signals for interpretation with a veterinarian.
Adverse-event reports help form a watch list, but they do not prove the medication caused the reaction and they are not a risk ranking between medications.
Official labels, package inserts, and reviewed summaries carry more weight than isolated reports.
Case reports and openFDA terms are useful for pattern awareness, but they are incomplete, can include multiple exposures, and do not estimate an individual pet's probability of harm.
Unsteady walking (ataxia) (1 reports), Loss of appetite (1 reports), Elevated aspartate aminotransferase (1 reports), Elevated alanine aminotransferase (1 reports), Discomfort NOS (1 reports)
Digestive (2), Neurologic (2), Behavior (2), Other (26)
Dog (18 reports), Cat (14 reports)
Retriever - Labrador (2), ['Terrier - Bull - American Pit', 'Dog (unknown)'] (1), Pointer (unspecified) (1), ['Shepherd Dog - German', 'Dog (unknown)'] (1). These are report metadata, not proof that a breed is at higher risk.
Verify whether Glucosamine fits the pet's species, current diagnosis, age, weight, organ status, pregnancy/lactation status, and concurrent medications.
Separate label-backed warnings from adverse-event reports and owner observations before changing the plan.
wobbly/unsteady walking, Loss of appetite, Elevated aspartate aminotransferase
Repeated vomiting or diarrhea. Severe lethargy (hard to wake, very low energy). Collapse or fainting.
Review status / Updated / Sources
Review status: Clinical reviewer not listed
Updated: April 15, 2026, 10:04 AM UTC
Side effects to monitor:
Most reported reactions:
Emergency warning signs:
Source-backed clinical checkpoints for quick review.
Official label facts first, then secondary summaries. Marketing content is separated below.
Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.
Filter stored openFDA reports by pet and report attributes. Counts describe reports in this data set, not risk.
Received 2026-03-23 · MSK · MSK
Received 2026-03-16 · MSK · MSK
Received 2025-11-19 · MSK · MSK
Received 2025-10-17 · MSK · MSK
Tap or hover a reaction to see what it means in plain language.
| Reaction | Body system | Cases | Species | Serious cases |
|---|---|---|---|---|
| Neurologic | 1 | Dog | 1 | |
| Digestive | 1 | Dog | 1 | |
| Other | 1 | Cat | 1 | |
| Other | 1 | Cat | 1 | |
| Other | 1 | Dog | 1 | |
| Other | 1 | Dog | 1 | |
| Other | 1 | Dog | 1 | |
| Other | 1 | Dog | 1 |
Species coverage: Dog (18) Cat (14)
| Reaction | Body system | Species | Seriousness | Frequency | Reports |
|---|---|---|---|---|---|
| Neurologic | Dog | Serious | - | 1 | |
| Digestive | Dog | Serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Other | Dog | Non-serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Cat | Non-serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Digestive | Cat | Non-serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Cat | Non-serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Neurologic | Dog | Serious | - | 1 | |
| Other | Cat | Non-serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Behavior | Dog | Serious | - | 1 | |
| Behavior | Cat | Serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Other | Dog | Serious | - | 1 |
The most useful source links appear first; full previews and metadata stay in the veterinary/professional layer.
Use original documents to confirm product-specific warnings, ingredients, and handling details with your veterinarian.
Full source previews and metadata remain in the veterinary/professional layer.
SPL · Structured Product Label
Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.
Quick facts and links to official labeling and safety signals.
Diagnosis-code mappings are not available for this medication yet.
Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.
Normalized identifiers (NDC/NADA/ANADA) and package metadata from regulator listings.
| Package NDC | Product NDC | Form / Route | Status |
|---|---|---|---|
| 16244-1004-1 | 16244 | - | |
| 45732-013-30 | 45732 | - | |
| 45732-013-60 | 45732 | - | |
| 45732-075-10 | 45732 | - | |
| 73309-352-01 | 73309 | - |
Documents are tiered by source trust: Official, Clinical, Manufacturer, Marketing.
Every non-trivial field is expected to include provenance and update timestamps.
Official sponsor/proprietary-name/application-status records linked by active ingredient.
| Product | Sponsor | Application | Status | Published |
|---|
Data source: FDA Animal Drugs @ FDA (public search export).
De-duplicated reaction terms grouped by body system from FDA openFDA reports (not verified; does not prove causation).
Showing top 5 for Digestive.
Showing top 5 for Neurologic.
Showing top 5 for Behavior.
Showing top 5 for Other.
Data source: FDA openFDA Animal & Veterinary adverse event reports.
These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.
Dog, ['Terrier - Bull - American Pit', 'Dog (unknown)'], Female, 12 year, 24.176 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Seizure NOS, Cough, Stiffness NOS, Falling, Clenched jaw… • Outcome: Ongoing
Dog, Pointer (unspecified), Male, 12 year, 27.216 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Vomiting • Outcome: Ongoing
Dog, ['Shepherd Dog - German', 'Dog (unknown)'], Male, 13 year, 31.842 kilogram • Drug: MSK, Unknown • Reactions: Vomiting, Reluctant to move, Unable to rise, Difficulty to rise, Weakness… • Outcome: Ongoing
Cat, Domestic Shorthair, Male, 11 year, 7.529 kilogram • Drug: MSK, Unknown • Reactions: Dilated pupils, Not sleeping, Behavioral disorder (unspecified), Restlessness • Outcome: Outcome Unknown
Dog, Retriever - Labrador, Male, 9 year, 29.483 kilogram • Drug: MSK, Tablet, Oral, Dose: 1 dose per animal • Reactions: Seizure NOS • Outcome: Recovered/Normal
Dog, Shepherd Dog - Australian, Female, 14 year, 25.5 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Lack of efficacy - NOS, Unable to stand, Proprioception deficit, Hind limb paresis, Death… • Outcome: Euthanized
Cat, Domestic Mediumhair, Male, 18 year, 5.761 kilogram • Drug: MSK, Solution/drops, Unknown • Reactions: Impaired vision, Behavioral disorder (unspecified), Gait abnormality, Blindness, Abnormal menace reflex test… • Outcome: Ongoing
Dog, Retriever - Labrador, Female, 16 year, 28.576 kilogram • Drug: MSK, Unassigned, Oral • Reactions: Lameness • Outcome: Outcome Unknown
Data source: FDA openFDA Animal & Veterinary adverse event reports.
No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.
No approved storage guidance is linked yet for this ingredient. Use manufacturer packaging and veterinary guidance for handling/storage.
Let others know your experience or advice regarding this medication.
This medication has not been reviewed by a veterinarian yet.