Roxee Medication Guide
Glucosamine
Medication reference facts with explicit FDA-approval, off-label, source-limited, and safety context. Roxee does not sell, prescribe, or dispense medications.
Veterinary professional?
Data freshness
Roxee has a partial reference profile for this medication. Some primary facts still need verification.
Sponsor, product, and application records imported from Animal Drugs @ FDA.
openFDA reaction terms and case summaries are supporting evidence, not proof of causality.
Source timing details
-
Reference facts:
Source Roxee
| Refreshed Jun 22, 2026, 10:45 AM UTC
The reference fact projection used for browse cards and quick facts.
-
Animal Drug Product Listing Directory (NDC):
Source FDA
| Refreshed Jun 22, 2026, 10:41 AM UTC
Package/product NDCs from FDA’s electronic listing directory (XLS).
- openFDA reaction terms: Source FDA openFDA | Refreshed Jun 22, 2026, 10:45 AM UTC
- openFDA case summaries: Source FDA openFDA | Refreshed Jun 22, 2026, 10:45 AM UTC
Glucosamine
Drug type: Generic ingredient • Branded profile • Not FDA-approved for animals
Species: Both
Approval status: Not FDA-approved as an animal drug. No FDA-approved animal-drug application is linked for this record. It may represent extra-label, human-drug, bulk-compounding, export-only, or otherwise unapproved animal-use source data; use only under veterinarian direction.
Medication Snapshot
Merged from the current Roxee medication system with field-level provenance, freshness, and completeness tracking.
Glucosamine
Senvelgo (velagliflozin oral solution) is approved in cats for control of hyperglycemia associated with diabetes mellitus. Species commonly shown: Both.
Indications / Uses
Senvelgo (velagliflozin oral solution) is approved in cats for control of hyperglycemia associated with diabetes mellitus.
Side Effects
Top reported reactions (openFDA): Vomiting, Lethargy (see also Central nervous system depression in 'Neurological'), Diarrhoea, Death by euthanasia, Seizure NOS, Decreased appetite.
FAQ
Source Transparency
- Verified source: https://www.roxee.ai/meds/
- Verified source: https://animaldrugsatfda.fda.gov
- Verified source: https://animaldrugsatfda.fda.gov/adafda/views/#/search
- Verified source: https://api.fda.gov/animalandveterinary/event.json
- Verified source: https://www.accessdata.fda.gov/spl/data/3bd845a1-a676-432b-acc3-1d0e767a60fe/3bd845a1-a676-432b-acc3-1d0e767a60fe.xml
- Last refreshed: Jun 22, 2026, 10:45 a.m.
- Last verified: Apr 15, 2026, 10:04 a.m.
- Validation status: Incomplete
Add to My Pet's Medications
Choose a pet, confirm current or past, and optionally add reminder notes.
Sign in to save this medication to your pet profile.
Sign in to continuePet Owner Quick Guide
Start here first for the safest next-step summary before the deeper medication detail.
Used for:
Your vet decides this. Here's what owners typically ask/watch for.
Dosing note:
Exact dosing depends on your pet's species, weight, and health status. Use your veterinarian's instructions for the exact dose and schedule.
What to watch for:
- wobbly/unsteady walking (1 reports)
- Heart murmur (1 reports)
- Head shake - behavioural disorder (1 reports)
When to call the vet:
- Repeated vomiting or diarrhea.
- Severe lethargy (hard to wake, very low energy).
- Collapse or fainting.
- Trouble breathing.
- Facial swelling or hives.
- Blood in vomit or stool.
What to tell or ask your vet today:
- Is this medicine the right fit for my pet’s current symptoms?
- Which warning signs mean I should call back right away?
- How should I handle missed doses or refusal to take the medicine?
Medication Research Insights
A source-aware map of what to know, what is uncertain, and what to verify with your veterinarian.
What to know
Roxee has limited cited overview evidence for Glucosamine; use the official documents and your veterinarian's instructions for product-specific decisions.
32 tracked reaction signals; 32 reported cases; 26 serious reports; 2 species groups. These are reporting and label-derived signals for interpretation with a veterinarian.
Adverse-event reports help form a watch list, but they do not prove the medication caused the reaction and they are not a risk ranking between medications.
Evidence tension
Official labels, package inserts, and reviewed summaries carry more weight than isolated reports.
Case reports and openFDA terms are useful for pattern awareness, but they are incomplete, can include multiple exposures, and do not estimate an individual pet's probability of harm.
Reaction signal map
Unsteady walking (ataxia) (1 reports), Heart murmur (1 reports), Head shake - behavioural disorder (1 reports), Head down (1 reports), Falling (1 reports)
Digestive (2), Neurologic (2), Behavior (2), Other (26)
Species and breed lens
Dog (20 reports), Cat (12 reports)
Shih Tzu (2), Domestic Shorthair (2), Retriever - Labrador (1), ['Retriever (unspecified)', 'Dog (unknown)'] (1). These are report metadata, not proof that a breed is at higher risk.
What your vet may verify
Verify whether Glucosamine fits the pet's species, current diagnosis, age, weight, organ status, pregnancy/lactation status, and concurrent medications.
Separate label-backed warnings from adverse-event reports and owner observations before changing the plan.
What to watch next
wobbly/unsteady walking, Heart murmur, Head shake - behavioural disorder
Repeated vomiting or diarrhea. Severe lethargy (hard to wake, very low energy). Collapse or fainting.
Vet source depth
- openFDA case USA-USFDACVM-2025-US-038382 · adverse_reaction · adverse reactions
- Structured Product Label · document · documents
Evidence
Review status / Updated / Sources
Review status: Clinical reviewer not listed
Updated: April 15, 2026, 10:04 AM UTC
- openFDA case USA-USFDACVM-2025-US-038382 · adverse_reaction
- Structured Product Label · document
Safety & side effects
Side effects to monitor:
- wobbly/unsteady walking
- Heart murmur
- Head shake - behavioural disorder
Most reported reactions:
- Unsteady walking (ataxia) (1 reports)
- Heart murmur (1 reports)
- Head shake - behavioural disorder (1 reports)
Emergency warning signs:
- Repeated vomiting or diarrhea.
- Severe lethargy (hard to wake, very low energy).
- Collapse or fainting.
- Trouble breathing.
Vet Fast Scan
Source-backed clinical checkpoints for quick review.
- Novipet SPL SPL
Quick Facts
Official label facts first, then secondary summaries. Marketing content is separated below.
Adverse Reactions
Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.
Reported case explorer
Filter stored openFDA reports by pet and report attributes. Counts describe reports in this data set, not risk.
Tap or hover a reaction to see what it means in plain language.
Grouped by Body System
Most Reported Reactions
| Reaction | Body system | Cases | Species | Serious cases |
|---|---|---|---|---|
| Neurologic | 1 | Dog | 1 | |
| Other | 1 | Cat | 1 | |
| Behavior | 1 | Dog | 1 | |
| Other | 1 | Dog | 1 | |
| Other | 1 | Dog | 1 | |
| Other | 1 | Dog | 1 | |
| Other | 1 | Dog | 1 | |
| Other | 1 | Dog | 1 |
Species coverage: Dog (20) Cat (12)
View detailed reaction table
| Reaction | Body system | Species | Seriousness | Frequency | Reports |
|---|---|---|---|---|---|
| Neurologic | Dog | Serious | - | 1 | |
| Digestive | Cat | Non-serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Behavior | Dog | Serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Other | Dog | Non-serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Digestive | Cat | Non-serious | - | 1 | |
| Other | Cat | Non-serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Cat | Non-serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Neurologic | Dog | Serious | - | 1 | |
| Other | Cat | Non-serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Behavior | Dog | Serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Cat | Serious | - | 1 |
- https://api.fda.gov/animalandveterinary/event.json · adverse_reaction · openFDA case USA-USFDACVM-2025-US-038382
Source Documents
The most useful source links appear first; full previews and metadata stay in the veterinary/professional layer.
Use original documents to confirm product-specific warnings, ingredients, and handling details with your veterinarian.
Full source previews and metadata remain in the veterinary/professional layer.
Owner handouts
0Official label / PI
0SPL
1FOI
0Novipet SPL
SPL · Structured Product Label
- https://www.accessdata.fda.gov/spl/data/3bd845a1-a676-432b-acc3-1d0e767a60fe/3bd845a1-a676-432b-acc3-1d0e767a60fe.xml · document · Structured Product Label
Veterinary reference (advanced)
Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.
At a Glance
Quick facts and links to official labeling and safety signals.
-
Reference facts:
Source Roxee
| Refreshed Jun 22, 2026, 10:45 AM UTC
The reference fact projection used for browse cards and quick facts.
-
Animal Drug Product Listing Directory (NDC):
Source FDA
| Refreshed Jun 22, 2026, 10:41 AM UTC
Package/product NDCs from FDA’s electronic listing directory (XLS).
- openFDA reaction terms: Source FDA openFDA | Refreshed Jun 22, 2026, 10:45 AM UTC
- openFDA case summaries: Source FDA openFDA | Refreshed Jun 22, 2026, 10:45 AM UTC
Diagnosis-code mappings are not available for this medication yet.
Counseling and Monitoring Highlights
Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.
Identifiers & Packages
Normalized identifiers (NDC/NADA/ANADA) and package metadata from regulator listings.
| Package NDC | Product NDC | Form / Route | Status |
|---|---|---|---|
| 16244-1004-1 | 16244 | - | |
| 45732-013-30 | 45732 | - | |
| 45732-013-60 | 45732 | - | |
| 45732-075-10 | 45732 | - | |
| 73309-352-01 | 73309 | - |
Enriched Documents
Documents are tiered by source trust: Official, Clinical, Manufacturer, Marketing.
-
Novipet SPL
• Structured Product Label • Official
FDA Structured Product Label from the electronic animal drug product listing directory.
Data Sources & Change Log
Every non-trivial field is expected to include provenance and update timestamps.
- monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-21)
- monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-20)
- monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-19)
- monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-17)
- monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-16)
- monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-16)
- side_effects: Top reported reactions (openFDA): Vomiting, Lethargy (see also Central nervous system depression in 'Neurological'), Diarrhoea, Death by euthanasia, Seizure NO… (Clinical, 2026-04-11)
- manufacturer_name: Novipet, Inc. (Official, 2026-06-22)
- manufacturer_name: Novipet, Inc. (Official, 2026-06-22)
- manufacturer_name: Novipet, Inc. (Official, 2026-06-21)
- manufacturer_name: Novipet, Inc. (Official, 2026-06-20)
- manufacturer_name: Novipet, Inc. (Official, 2026-06-13)
- manufacturer_name: Novipet, Inc. (Official, 2026-06-12)
- manufacturer_name: Novipet, Inc. (Official, 2026-06-12)
- manufacturer_name: Novipet, Inc. (Official, 2026-06-11)
- manufacturer_name: Novipet, Inc. (Official, 2026-06-11)
- manufacturer_name: Novipet, Inc. (Official, 2026-06-10)
- manufacturer_name: Novipet, Inc. (Official, 2026-06-09)
- manufacturer_name: Novipet, Inc. (Official, 2026-06-08)
- manufacturer_name: Novipet, Inc. (Official, 2026-06-07)
- side_effects updated 2026-06-22 10:45 by etl_backfill • Backfilled from existing medication fields
- side_effects updated 2026-06-22 10:04 by etl_backfill • Backfilled from existing medication fields
- side_effects updated 2026-06-21 05:18 by etl_backfill • Backfilled from existing medication fields
- side_effects updated 2026-06-20 20:58 by etl_backfill • Backfilled from existing medication fields
- side_effects updated 2026-06-13 11:33 by etl_backfill • Backfilled from existing medication fields
- side_effects updated 2026-06-12 10:42 by etl_backfill • Backfilled from existing medication fields
- side_effects updated 2026-06-12 10:04 by etl_backfill • Backfilled from existing medication fields
- side_effects updated 2026-06-11 19:22 by etl_backfill • Backfilled from existing medication fields
- side_effects updated 2026-06-11 18:40 by etl_backfill • Backfilled from existing medication fields
- side_effects updated 2026-06-10 10:05 by etl_backfill • Backfilled from existing medication fields
- side_effects updated 2026-06-08 10:05 by etl_backfill • Backfilled from existing medication fields
- side_effects updated 2026-06-07 10:05 by etl_backfill • Backfilled from existing medication fields
- side_effects updated 2026-06-06 10:05 by etl_backfill • Backfilled from existing medication fields
- side_effects updated 2026-06-05 10:05 by etl_backfill • Backfilled from existing medication fields
- side_effects updated 2026-06-04 10:05 by etl_backfill • Backfilled from existing medication fields
- side_effects updated 2026-06-03 10:05 by etl_backfill • Backfilled from existing medication fields
- side_effects updated 2026-06-02 10:05 by etl_backfill • Backfilled from existing medication fields
- side_effects updated 2026-06-01 10:40 by etl_backfill • Backfilled from existing medication fields
- side_effects updated 2026-06-01 10:05 by etl_backfill • Backfilled from existing medication fields
- side_effects updated 2026-05-31 10:05 by etl_backfill • Backfilled from existing medication fields
FDA Products & Applications (Animal Drugs @ FDA)
Official sponsor/proprietary-name/application-status records linked by active ingredient.
| Product | Sponsor | Application | Status | Published |
|---|
Data source: FDA Animal Drugs @ FDA (public search export).
Top Reported Reactions (openFDA)
De-duplicated reaction terms grouped by body system from FDA openFDA reports (not verified; does not prove causation).
Showing top 5 for Digestive.
Showing top 5 for Neurologic.
Showing top 5 for Behavior.
Show more (21)
Showing top 5 for Other.
Data source: FDA openFDA Animal & Veterinary adverse event reports.
Adverse Event Case Summaries (openFDA)
These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.
Dog, Retriever - Labrador, Male, 5 year, 39.463 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Limb non-weight bearing, Bone and joint disorder NOS, Other abnormal test result NOS, Abnormal radiograph finding, Urinary tract obstruction/blockage… • Outcome: Euthanized
- Report ID: USA-USFDACVM-2025-US-074601
- Serious AE: Yes
- Treated For AE: Yes
- Sex: Male
- Age: 5.00 Year
- Weight: 39.463 Kilogram
- Case-reported brand: MSK
- Case-reported manufacturer: MSK
- Route: Unknown
- Form: Unassigned
Dog, Shih Tzu, Female, 14 year, 6.35 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Malaise, Not himself/herself, Confusion, Sleepiness - systemic disorder, Arched back… • Outcome: Euthanized
- Report ID: USA-USFDACVM-2025-US-072769
- Serious AE: Yes
- Treated For AE: Yes
- Sex: Female
- Age: 14.00 Year
- Weight: 6.350 Kilogram
- Case-reported brand: MSK
- Case-reported manufacturer: MSK
- Route: Unknown
- Form: Unassigned
Dog, Shih Tzu, Male, 14.83 year, 7.076 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Renal failure, Weight loss, Seizure NOS, Vocalisation, Anaemia NOS… • Outcome: Euthanized
- Report ID: USA-USFDACVM-2025-US-072872
- Serious AE: Yes
- Treated For AE: Yes
- Sex: Male
- Age: 14.83 Year
- Weight: 7.076 Kilogram
- Case-reported brand: MSK
- Case-reported manufacturer: MSK
- Route: Unknown
- Form: Unassigned
Dog, ['Retriever (unspecified)', 'Dog (unknown)'], Female, 13 year, 38.555 kilogram • Drug: MSK, Unknown • Reactions: Urinary incontinence • Outcome: Ongoing
- Report ID: USA-USFDACVM-2025-US-070900
- Serious AE: No
- Treated For AE: Yes
- Sex: Female
- Age: 13.00 Year
- Weight: 38.555 Kilogram
- Case-reported brand: MSK
- Case-reported manufacturer: MSK
- Route: Unknown
Cat, Domestic Shorthair, Male, 6 year, 5.352 kilogram • Drug: MSK, Oral, Dose: 1 tablet per animal • Reactions: Chronic kidney disease • Outcome: Outcome Unknown
- Report ID: USA-USFDACVM-2025-US-072139
- Serious AE: No
- Treated For AE: No
- Sex: Male
- Age: 6.00 Year
- Weight: 5.352 Kilogram
- Case-reported brand: MSK
- Case-reported manufacturer: MSK
- Route: Oral
- Dose: 1 tablet per animal
Dog, Dog (unknown), Male, 11 year, 19.3 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Musculoskeletal disorder NOS, Walking difficulty • Outcome: Ongoing
- Report ID: USA-USFDACVM-2025-US-070411
- Serious AE: No
- Treated For AE: No
- Sex: Male
- Age: 11.00 Year
- Weight: 19.300 Kilogram
- Case-reported brand: MSK
- Case-reported manufacturer: MSK
- Route: Unknown
- Form: Unassigned
Cat, Siberian, Female, 15 year, 5.4 kilogram • Drug: MSK, Oral • Reactions: Vomiting, Defect Unknown/Not Specified • Outcome: Recovered/Normal
- Report ID: USA-USFDACVM-2025-US-072611
- Serious AE: No
- Treated For AE: No
- Sex: Female
- Age: 15.00 Year
- Weight: 5.400 Kilogram
- Case-reported brand: MSK
- Case-reported manufacturer: MSK
- Route: Oral
Cat, Domestic Shorthair, Male, 14 year, 5.262 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Localised pain NOS, Wobbliness, Not eating, Anaemia NOS, Elevated alanine aminotransferase… • Outcome: Ongoing
- Report ID: USA-USFDACVM-2025-US-068717
- Serious AE: Yes
- Treated For AE: Yes
- Sex: Male
- Age: 14.00 Year
- Weight: 5.262 Kilogram
- Case-reported brand: MSK
- Case-reported manufacturer: MSK
- Route: Unknown
- Form: Unassigned
Data source: FDA openFDA Animal & Veterinary adverse event reports.
Overdose Information
No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.
Storage & Handling
No approved storage guidance is linked yet for this ingredient. Use manufacturer packaging and veterinary guidance for handling/storage.
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